bims-evares Biomed News
on Evaluation of research
Issue of 2020–06–21
thirty papers selected by
Thomas Krichel, Open Library Society



  1. Zhonghua Yu Fang Yi Xue Za Zhi. 2020 Jun 15. 54(0): E035
      Objective: To analyze the characteristics and citations of articles in Chinese Journal of Preventive Medicine from 2014 to 2017, and discuss the academic level and quality of the journal. Methods: All the literatures published in Chinese Journal of Preventive Medicine from 2014 to 2017 were retrieved through the Chinese Medical Citation index, and the citation frequency data in China's core journals of science and technology from 2014 to 2018 was obtained through Institute of Scientific and Technical Information of China(the cut-off time was October 2018). The citation status of articles published in Chinese Journal of Preventive Medicine was statistically analyzed by the method of literature metrology. The main indicators included the citation rate of articles published in each year, the citation frequency of all articles, the citation status of individual papers and authors, the regional and high-yield institution distribution of cited authors, and the main citation journals. Results: From 2014 to 2017, a total of 929 articles were published in 19 columns of Chinese Journal of Preventive Medicine, and the number of each year was 253 (27.23%), 231 (24.87%), 224 (24.11%) and 221 (23.79%), respectively. The total number of published pages was 3 564, and the average number of articles was 3.45 pages. A total of 28 key topics have been published. The total citation was 3 861 times, with 4.16 times per paper and 1.08 times per page. Among them, 161 papers were not cited, accounting for 17.33%. The maximum citation frequency of a single paper was 68 times. There were good citations in the columns of standard/guide/consensus and methodology introduction. There was no correlation between fund project support and paper citation. But the cited rate (93.67%) and cited frequency of special issue [M (P(25), P(75))=3 (1, 6)] were higher compared with the cited rate (80.42%; χ(2)=16.08, P<0.001) and cited frequency [M (P(25), P(75))=2 (1, 6); Z=2.56, P= 0.010) of free- lance articles. A total of 15 authors were cited more than 25 times, and 15 articles were cited more than 20 times. There were 213 institutions involved in the 768 cited papers, among which 12 institutions were cited more than 50 times. The authors of the cited papers were distributed in 29 provinces (autonomous regions, municipalities directly under the central government). From 2014 to 2018, a total of 281 journals cited papers published in our journal, 12 of which were cited more than 50 times. Conclusion: The quality of the literature in Chinese Journal of Preventive Medicine is high and the journal has a strong influence in the field of preventive medicine and public health in China. The editorial department should adjust the column setting timely, strengthen the planning of key topic selection and the solicitation and publicity of excellent papers, reduce the number of papers cited by zero, and further improve the influence of the magazine.
    Keywords:  Bibliometrics; Periodicals; Preventive Medicine; Statistics
    DOI:  https://doi.org/10.3760/cma.j.cn112150-20200614-00876
  2. J Oral Pathol Med. 2020 Jun 18.
       OBJECTIVES: A systematic bibliometric analysis of the structure of knowledge was performed to investigate the co-word analysis, the co-citation analysis, and the social network analysis regarding Complex Oral Sensitivity Disorder (COSD).
    METHODS: Web of Science database from 1985 to 2018 was systematically searched to identify all relevant articles using the MeSH terms "complex oral sensitivity disorder" and all synonyms used in the literature. We included original articles, review articles, letters to the editor, and book chapters in the English language and in 27 different ISI categories of medical sciences. Several bibliometric indicators were used.
    RESULTS: The co-word analysis identified 741 KeyWords Plus (KWP) grouped into 4 different clusters. The terms "pain", "management", "prevalence", "efficacy" reached the highest centrality, whereas the top 10 KWP had a frequency of 7%-29% in 443 articles. Over a period of 32 years, a complex thematic evolution occurred, going from 2 to 6 different themes, and the KWP migration rate from one cluster to another ranged from 11% to 100%. The co-citation network analysis based on the complete reference list (5932 references) of 443 articles identified only 2 clusters for journals, authors, and articles. The most prominent co-cited journal was "Oral Surgery Oral Medicine Oral Pathology" (centrality: 171.75), the most co-cited author was "Grushka M" (centrality: 330.95), and the most co-cited article was "Grushka M. Oral Surg Oral Med Oral Pathol. 1987;63:30-36" (centrality: 269.79). On the other hand, the direct citation network revealed that "Scala A et al, 2003" reached both the highest global (GCS=231) and local citation score (LCS=161). Lastly, the social network analysis revealed an isolated collaboration among groups of authors, or countries or institutions. The worldwide collaboration analysis indicated that USA-Israel and United Kingdom-Italy were the most collaborative countries.
    CONCLUSIONS: The structure of knowledge of publications on COSD revealed that research in this field has been dominated by few core topics and a limited collaboration among authors and institutions from different countries. More multicenter studies on COSD are warranted in the near future when launching new projects.
    Keywords:  BMS; COSD; bibliometric; complex oral sensitivity disorder; intellectual structure; systematic
    DOI:  https://doi.org/10.1111/jop.13077
  3. Turk J Anaesthesiol Reanim. 2020 Jun;48(3): 235-243
       Objective: Despite the rapid increase in economy and general scientific activities, it is thought that the same increase may not be seen in publication quality. We aimed at evaluating the current scientific performance of our country in the field of anaesthesiology in international journals with a high impact value from 2008 to the present.
    Methods: The list of anaesthesiology journals in the Science Citation Index (SCI) and SCI-Expanded (SCI/SCI-E) index and the ISSN numbers were obtained. The studies published in these journals from Turkey and from 2007 to September 2018 were listed. The year of publication, subject, method and number of citations and the conducting institution of each study were recorded. Institutions with the highest publications and institutions with the highest number of citations were identified.
    Results: A total of 3,486 articles were found. Of them, 583 (16.7%) publications were from Turkey. The highest number of publications was in 2018 (14.4%) and the lowest was in 2015 (5.3%).
    Conclusion: Although there seems to be a significant increase in the number of publications in recent years, the same increase is not reflected in the publication quality evaluation criteria and there is no increase in the number of prospective randomised controlled trials and citations.
    Keywords:  Anaesthesiology; Turkey; bibliometric analysis; impact factor
    DOI:  https://doi.org/10.5152/TJAR.2019.19942
  4. Ann Thorac Surg. 2020 Jun 12. pii: S0003-4975(20)30904-8. [Epub ahead of print]
       BACKGROUND: Altmetric scores are increasingly utilized as non-traditional metrics of scholarly impact that capture article social media attention. This study aims to characterize articles from the Annals of Thoracic Surgery that achieved the greatest online reach over a longitudinal period.
    METHODS: The 50 articles with the highest Altmetric scores published in the Annals of Thoracic Surgery for the years 2013, 2015, and 2017 were identified. Spearman rank correlation coefficient was used to assess correlation of Altmetric scores with citations. Independent predictors of Altmetric scores (≥25) were identified through univariable and multivariable logistic regression analysis.
    RESULTS: Over time, article Altmetric scores increased significantly (2013, 11.9; 2015, 24.8; 2017, 75.3; p<0.001), with more authors on Twitter in recent years to disseminate scholarly work (2013, 10%; 2015, 20%; 2017, 42%; p<0.001). Recent articles attracted greater attention from news outlets (2013, 1.02; 2015, 2.36; 2017, 7.48; p<0.001) and tweets (2013, 1.84; 2015, 6.68; 2017, 27.8; p<0.001), reaching a larger readership via Twitter (2013, 4,210; 2015, 19,300; 2017, 66,800; p<0.001). Log-transformed Altmetric scores were correlated with log-transformed citations for articles published in 2017 (rs=0.40; p=0.02). On multivariable analysis, tweets (OR 1.27 [95%CI 1.01-1.61]; p=0.044) and mentions by news outlets (OR 30.49 [95%CI 4.03-230.16]; p=0.001) were predictive of high Altmetric scores.
    CONCLUSIONS: This longitudinal analysis demonstrates that social media attention related to top performing articles has increased in recent years. Social media is an effective tool to increase article reach and knowledge translation, with Altmetric scores that correlated with citations.
    DOI:  https://doi.org/10.1016/j.athoracsur.2020.04.102
  5. Chem Biol Interact. 2020 Jun 10. pii: S0009-2797(20)30672-4. [Epub ahead of print] 109177
      Since its inception in 1969, Chemico-Biological Interactions (CBI) has persistently published high quality research articles. As part of the journal's golden anniversary (50 years), we performed an electronic search on Scopus to get all publications details. Based on citescore, ranking & percentile, CBI holds 21st position in the top 113 relevant journals (in 2018). CBI also completed publications of 8005 manuscripts in March 2020. The highest documents were articles (6972/87.09%) followed by conference papers (588/7.34%) and reviews (252/3.14%). The maximum number of publications (385) was recorded in 2019, followed by 366 (in 2010) and 336 in 2016. Furthermore, details of the top 50 countries, top 50 authors and top 20 institutes with total publications, h-index, total citations and without selfcitations (WSC) are provided. USA (2371), China (786) and United Kingdom (658) are the top three countries, O'Brien, P.J (48), Maser, E. (45) and Lockridge, O. (35) are the top three authors and Karolinska Institutet (144), Stockholm University (102) & Ministry of Education China (94) are the top three institutes involved in research publications. More than eighty-four thousand 84,000 key words were amassed from scopus and after critical analysis we proposed a common sequence and connectivity. The top 200 articles, 200 reviews and 200 conference papers were analyzed by Vosviewer for various parameters. While, the top three (3) research articles and reviews are briefly described. The bibliometric analyses confirm a noteworthy growth of CBI in research publications and scientometric performance.
    Keywords:  CBI; Scopus; VOSviewer
    DOI:  https://doi.org/10.1016/j.cbi.2020.109177
  6. J Diabetes Metab Disord. 2020 Jun;19(1): 163-177
       Objectives: To introduce bibliometric features of Iranian documents on microbiota and to provide descriptive information about retrieved documents related to the medical sciences and documents utilizing molecular techniques for microbiota detection.
    Methods: This is a descriptive bibliometric study of all Iranian documents on microbiota in any language that were indexed in Scopus before 7 September 2019. We assessed the research performance through statistical analysis of the bibliometric indicators, including number of publications, citations, institutions and journals activities, co-citations and bibliographic couplings, and network analysis of co-authorships, countries' collaborations, terms and keywords.
    Results: We extracted 425 relevant documents, 260 of which pertain to the medical sciences. The most focused microbiota modulating interventions and diseases in 33 clinical trials are 'synbiotics' (n = 8) and 'probiotics' (n = 8), and 'Obesity' (n = 3) and 'non-alcoholic fatty liver disease' (n = 3), respectively. During the last decade, Iranian microbiota publications have increasingly grown with a constant upward slope, particularly in the area of medical sciences after 2016. Citation counting reveals that originals and reviews have been cited 4221 times, with an average 10.76 citations and H-index of 34. The most significant performance in publishing Iranian microbiota documents belongs to 'Tehran University of Medical Sciences' as the active institution (n = 89 publications) and the supporting sponsor (n = 19), 'Microbial Pathogenesis' as the productive journal (n = 12), 'Seidavi A' as the most authorships (n = 19), and 'the United States' as the collaborative country (n = 46).
    Conclusions: The qualitative and quantitative information of this study will be a practical guidance for future study planning and policy-decision making.
    Keywords:  Bibliometrics; Iran; Microbiome; Microbiota; Scientometrics
    DOI:  https://doi.org/10.1007/s40200-020-00488-2
  7. Medicine (Baltimore). 2020 Jun 12. 99(24): e20586
      Like research in general internal medicine, family medicine research can play an important role in improving medical knowledge. We aimed to compare articles published in family medicine journals with articles published in general internal medicine journals. In this bibliometric study, we retrieved 658 randomly selected quantitative articles published in 2016 in 18 high impact factor journals of family medicine and general internal medicine. We extracted the following data: author (gender, number of publications, and place of residence of the first author), paper (number of participants, study design) and journal characteristics (journal discipline, 2015 impact factor). We compared the two groups of articles, using multivariate logistic regressions adjusted for impact factor and intra-cluster correlations. The first author of the articles published in family medicine journals, compared to general internal medicine journals, was more often a woman (OR 2.8 [95%CI 1.8-4.4], P-value < .001), living in the Western world (OR 14.4 [95%CI 6.0-34.4], P-value < .001), and a less experienced researcher (<5 vs >15 publications: OR 2.4 [95%CI 1.5-4.0], P-value .01). In addition, these studies generally included more participants (>1000 vs <100: OR 3.5 [95%CI 1.4-8.6], P-value .02). There was no statistically significant difference in the study design between the two groups of articles (P-value .25). Despite some differences between the two groups of articles, studies published in family medicine journals do not appear to be any less ambitious in terms of study design and sample size than those published in general internal medicine journals.
    DOI:  https://doi.org/10.1097/MD.0000000000020586
  8. Turk J Anaesthesiol Reanim. 2020 Jun;48(3): 223-228
       Objective: To the best of our knowledge, no bibliometric studies have characterised the paediatric anaesthesia research in Ireland. In this study, we aim to analyse the research output from two anaesthetic departments in Irish paediatric hospitals.
    Methods: A Scopus database search was conducted to identify the publications from 2007 to 2018 of the departments of anaesthesia and intensive care medicine in the Children's University Hospital, Temple Street (CUH), and Our Lady's Children's Hospital, Crumlin (OLCHC).
    Results: The Irish publications in paediatric anaesthesia and intensive care included 108 publications. CUH and OLCHC published 37 (34.9%) and 73 (68.8%) documents, respectively, with 6 (5.6%) documents affiliated with both hospitals. The number of original research articles was 28 (75.7%) for CUH versus 46 (63%) for OLCHC. The number of published reviews was 5 (13.5%) for CUH versus 11 (15.1%) for OLCHC. Over the last 2 years (2016, 2017), the number of OLCHC publications was almost double (13 and 14 publications) that of CUH (4 and 6 publications). For CUH, only two publications were in specialised journals. For OLCHC, 18 publications were in specialised journals, in addition to four publications in high-ranked journals. The mean impact factor for CUH publications was 3.78 (standard deviation [SD], 7.19) versus 4.52 (SD, 10.56) for OLCHC. From OLCHC, 20 authors published with a median h-index of 2.00 (interquartile range, 0-4.25), versus 14 authors form CUH with a median h-index of 1.50 (1.00-4.50).
    Conclusion: Anaesthetic publications from the two Irish paediatric hospitals are unexceptional and with limited cooperation between the two hospitals. Research plans should be implemented.
    Keywords:  Bibliometric analysis; Ireland; Irish paediatric hospitals; paediatric anaesthesia; paediatric intensive care
    DOI:  https://doi.org/10.5152/TJAR.2019.06787
  9. Burns. 2020 May 16. pii: S0305-4179(20)30354-5. [Epub ahead of print]
       BACKGROUND: The number of citations an article receives is a reassuring marker for its influence in the academic world.
    OBJECTIVE: We aimed to discover characteristics of dermatology articles that may impact their citation.
    METHODS: This cross-sectional study collected and analyzed articles published between January and June 2013 from ten highest impact dermatology journals. The study included manuscript characteristics i.e. the length of an article, the presence of visual aids, accessibility, originality, and clarity. Citation analysis statistics required multiple tools such as linear regression, point-biserial correlation, Spearman's rank-order correlation, and Kruskal-Wallis to determine the association between these study variables and the number of citations of articles.
    RESULTS: Of 748 articles included in our study, the number of citations ranged from 0 to 814 (median: 18), with weak positive correlations to the length of manuscript (word count: rs 0.3, p<0.001; pages: rs 0.3, p<0.001). Having a structured abstract (rpb -0.15, p<0.001) and increasing number of references (rs -0.26, p<0.001) showed a negative correlation. Studies originating in North America were associated with higher citations, followed by Europe and Asia (p<0.001). Review articles had a higher number of citations (p<0.001).
    CONCLUSIONS: We found that the number of words and the number of pages within a dermatology manuscript had the strongest positive correlation for a higher citation count. The results of this study can benefit authors who may improve the citation of their articles by utilizing this bibliometric study when assembling their manuscript.
    Keywords:  Bibliometrics; Dermatology
    DOI:  https://doi.org/10.1016/j.burns.2020.05.002
  10. J Clin Epidemiol. 2020 Jun 12. pii: S0895-4356(19)30604-3. [Epub ahead of print]
       OBJECTIVE: The objectives of this study were to evaluate the relationship between authorship networking as well as socioeconomic factors with scientific productivity across Latin-America (LATAM).
    METHODS: In a bibliometric analysis of cancer-related Latin-American publications the relationship between authorship network indicators, sociodemographic factors and number of peer reviewed indexed publications per country was explored. A systematic review of the literature for cancer publications between 2000 and 2018 using the Scopus database, limited to Latin-American authors was used for the construction of co-authorship and publication networks and their respective metrics. Sociodemographic variables including percentage of invested GDP in research, population as well as cancer incidence were also estimated. Multiple linear regression models were constructed to determine the relationship between productivity and the aforementioned variables.
    RESULTS: 8528 articles across 9 countries were included. Brazil was the most productive nation with 41.8% of identified references followed by Mexico (16.6%) and Argentina (12.9%). LATAM experienced a 9% growth in number of publications across the studied time frame. After analyzing networking and sociodemographic variables; number of authors in a collaboration network and percentage of invested GDP were associated with high productivity yielding a multiple regression model with an R2 value of 0.983.
    CONCLUSIONS: This study indicates that extensive authorship networking as well as a high investment in research strongly predict cancer related productivity.
    Keywords:  Bibliometrics; Latin America; Neoplasms; Publications; Scholarly Communication
    DOI:  https://doi.org/10.1016/j.jclinepi.2020.05.033
  11. J Med Internet Res. 2020 Jun 16. 22(6): e18457
       BACKGROUND: Studies using Taiwan's National Health Insurance (NHI) claims data have expanded rapidly both in quantity and quality during the first decade following the first study published in 2000. However, some of these studies were criticized for being merely data-dredging studies rather than hypothesis-driven. In addition, the use of claims data without the explicit authorization from individual patients has incurred litigation.
    OBJECTIVE: This study aimed to investigate whether the research output during the second decade after the release of the NHI claims database continues growing, to explore how the emergence of open access mega journals (OAMJs) and lawsuit against the use of this database affect the research topics and publication volume and to discuss the underlying reasons.
    METHODS: PubMed was used to locate publications based on NHI claims data between 1996 and 2017. Concept extraction using MetaMap was employed to mine research topics from article titles. Research trends were analyzed from various aspects, including publication amount, journals, research topics and types, and cooperation between authors.
    RESULTS: A total of 4473 articles were identified. A rapid growth in publications was witnessed from 2000 to 2015, followed by a plateau. Diabetes, stroke, and dementia were the top 3 most popular research topics whereas statin therapy, metformin, and Chinese herbal medicine were the most investigated interventions. Approximately one-third of the articles were published in open access journals. Studies with two or more medical conditions, but without any intervention, were the most common study type. Studies of this type tended to be contributed by prolific authors and published in OAMJs.
    CONCLUSIONS: The growth in publication volume during the second decade after the release of the NHI claims database was different from that during the first decade. OAMJs appeared to provide fertile soil for the rapid growth of research based on NHI claims data, in particular for those studies with two or medical conditions in the article title. A halt in the growth of publication volume was observed after the use of NHI claims data for research purposes had been restricted in response to legal controversy. More efforts are needed to improve the impact of knowledge gained from NHI claims data on medical decisions and policy making.
    Keywords:  National Health Insurance; PubMed; administrative claims data; bibliometric analysis; open access journals; text mining
    DOI:  https://doi.org/10.2196/18457
  12. Ann Med Surg (Lond). 2020 Jul;55 280-286
       Background: Total hip replacement (THR) is one of the most successful surgical treatment for advanced hip osteoarthritis. Some surgical approaches for THR have been established, one of it is Direct Anterior Approach (DAA), which is a relatively new and less commonly used, especially in Asian countries. This review aims to consolidate information from PubMed on the direct anterior approach (DAA) for total hip replacement (THR) in Asian countries.
    Purpose: To collect and consolidate information from PubMed on the total hip replacement (THR) using the direct anterior approach (DAA) in Asian countries.
    Methods: A search on the PubMed was done for DAA for THR. There were 461 search results about the DAA for THR publications obtained in total, and 51 articles meet the criteria were analyzed for details. The details include top countries publishing the topics, number of publications per year, top 5 journal publishing the DAA for THR topics, top 5 first authors publishing the articles on this topic, and top 5 author on all position published this topic.
    Results: The Journal of Arthroplasty was the leading publisher on this topic, with 10 articles published. Author Yasuhiro Homma, Tomonori Baba, and Kazuhiro Oinuma published the most number with 9 articles as one of the authors. Japan is the leading country for the publication on this topic with 34 published journals in total.
    Conclusion: The number of published articles in Asian country per year is still inconsistent, with one year without any publication on this topic. Searching the data on the DAA for THR in PubMed bestow useful information about good sources of publication on this topic.
    Keywords:  Asia; Database search; Direct anterior approach (DAA); Hip; PubMed; Total hip replacement (THR)
    DOI:  https://doi.org/10.1016/j.amsu.2020.06.001
  13. Cancer Immunol Immunother. 2020 Jun 15.
      Cancer immunotherapy is a rapidly growing field that is completely transforming oncology care. Mining this knowledge base for biomedically important information is becoming increasingly challenging, due to the expanding number of scientific publications, and the dynamic evolution of this subject with time. In this study, we have employed a literature-mining approach that was used to analyze the cancer immunotherapy-related publications listed in PubMed and quantify emerging trends. A total of 93,033 publications published in 5055 journals have been retrieved, and 141 meaningful topics have been identified, which were further classified into eight distinct categories. Statistical analysis indicates a mean annual increase in the number of published papers of approximately 8% in the last 20 years. The research topics that exhibited the highest trends included "immune checkpoint inhibitors," "tumor microenvironment," "HPV vaccination," "CAR T-cells," and "gene mutations/tumor profiling." The top identified cancer types included "lung," "colorectal," and "breast cancer," and a shift in popularity from hematological to solid tumors was observed. As regards clinical research, a transition from early phase clinical trials to randomized control trials was recorded, indicating that the field is entering a more advanced phase of development. Overall, this mining approach provided an unbiased analysis of the cancer immunotherapy literature in a time-conserving and scale-efficient manner.
    Keywords:  Cancer immunotherapy; LDA; Literature mining; Topic modeling; Trends analysis
    DOI:  https://doi.org/10.1007/s00262-020-02630-8
  14. Nat Neurosci. 2020 Jun 19.
      Similarly to many scientific disciplines, neuroscience has increasingly attempted to confront pervasive gender imbalances. Although publishing and conference participation are often highlighted, recent research has called attention to the prevalence of gender imbalance in citations. Because of the downstream effects of citations on visibility and career advancement, understanding the role of gender in citation practices is vital for addressing scientific inequity. Here, we investigate whether gendered patterns are present in neuroscience citations. Using data from five top neuroscience journals, we find that reference lists tend to include more papers with men as first and last author than would be expected if gender were unrelated to referencing. Importantly, we show that this imbalance is driven largely by the citation practices of men and is increasing over time as the field diversifies. We assess and discuss possible mechanisms and consider how researchers might approach these issues in their own work.
    DOI:  https://doi.org/10.1038/s41593-020-0658-y
  15. Ir J Med Sci. 2020 Jun 15.
       BACKGROUND: The proportion of abstracts presented at medical conferences that are subsequently published is a potentially useful surrogate for the quality of the material presented. The mean publication percentage for paediatric conference abstracts reported in the literature is 39%. The publication of abstracts presented at the Irish Paediatric Association's (IPA) annual conference have not previously been explored.
    AIM: To identify the subsequent publication proportion for abstracts presented at the IPA annual conference and to identify factors associated with a higher likelihood of publication.
    METHODS: As 95% of publications occur within 5 years of conference presentation, abstracts from the 2008 to 2012 IPA conferences were selected for analysis. A PubMed/Medline search was conducted using the author's names and, if required, abstract keywords. For comparability with previous studies, articles were deemed published if they were full journal articles, contained at least one similar author and reported similar outcomes.
    RESULTS: Over the 5-year study period, 584 IPA abstracts were presented. The percentage of abstracts published was 19.7%. One hundred and fifteen articles were published in 45 different journals; 31 (27%) of these were published in the Irish Medical Journal. The percentage of abstracts published was significantly higher for oral presentations (23% vs. 15%; p = 0.012), university-associated abstracts (31% vs. 16%; p < 0.001) and interventional studies (52% vs. 18%; p < 0.001). On multivariate analysis, only university association and interventional studies remained significantly associated with publication.
    CONCLUSION: The percentage of IPA abstracts that were published was low when compared internationally. Further analysis is required to explore the reasons underpinning this.
    Keywords:  Abstract; Medical conference; Paediatrics; Publishing
    DOI:  https://doi.org/10.1007/s11845-020-02277-5
  16. Elife. 2020 Jun 15. pii: e58807. [Epub ahead of print]9
      The COVID-19 pandemic has resulted in school closures and distancing requirements that have disrupted both work and family life for many. Concerns exist that these disruptions caused by the pandemic may not have influenced men and women researchers equally. Many medical journals have published papers on the pandemic, which were generated by researchers facing the challenges of these disruptions. Here we report the results of an analysis that compared the gender distribution of authors on 1893 medical papers related to the pandemic with that on papers published in the same journals in 2019, for papers with first authors and last authors from the United States. Using mixed-effects regression models, we estimated that the proportion of COVID-19 papers with a woman first author was 19% lower than that for papers published in the same journals in 2019, while our comparisons for last authors and overall proportion of women authors per paper were inconclusive. A closer examination suggested that women's representation as first authors of COVID-19 research was particularly low for papers published in March and April 2020. Our findings are consistent with the idea that the research productivity of women, especially early-career women, has been affected more than the research productivity of men.
    Keywords:  COVID-19; bias; bibliometrics; gender; human; human biology; medicine; meta-research; publishing
    DOI:  https://doi.org/10.7554/eLife.58807
  17. Reg Anesth Pain Med. 2020 Jun 18. pii: rapm-2019-101139. [Epub ahead of print]
       BACKGROUND: Numerous factors are considered in the academic promotion of pain medicine physicians. In this study, we investigated the importance of research productivity, career duration, leadership, and gender on attaining professorship in chronic pain medicine fellowship programs in the USA.
    METHODS: We identified 98 pain fellowship programs in the American Medical Association Fellowship and Residency Electronic Interactive Database. Faculty demographics and institutional characteristics were obtained from institutional websites, and h-index (number of publications (h) cited at least h times) and m-index (h-index divided by research career duration) were calculated from Scopus. A nested mixed effect hierarchical modeling was used to determine factors that were associated with attaining professorship.
    RESULTS: A total of 696 chronic pain medicine faculty members from 98 academic pain fellowship programs were identified, of whom 74.7% were males. For the 15.5% who were full professors, the median h-index was 16.5 (6.0 to 30.0), the median career duration was 20.5 (16.0 to 27.0) years, and the median m-index was 0.7 (0.3 to 1.3). In an adjusted analysis, the top quartile (compared with bottom) h-index (OR 6.27; 95% CI: 2.11 to 18.59), publication citations (OR 1.13; 95% CI: 1.10 to 1.21), division chief position (OR 3.72; 95% CI: 1.62 to 8.50), institutions located in the western region (OR 3.81; 95% CI: 1.52 to 9.57), and graduating from a foreign medical school (OR 1.98; 95% CI: 1.10 to 3.92) were independently associated with attaining professorship (p<0.05), but gender was not (p=0.71).
    CONCLUSIONS: Our study shows that, higher h-index, publication citations, division chief position, affiliation at a lower tier medical school, and location in the Western region were independently associated with full professorship, whereas gender was not. The identified variables for professorship may be considered as factors in faculty promotions.
    Keywords:  clinical pain; education; pain medicine
    DOI:  https://doi.org/10.1136/rapm-2019-101139
  18. JAMA Ophthalmol. 2020 Jun 18.
       Importance: The description of racial and ethnic data in human trials is relatively unregulated, leading to potential confusion with and inconsistent reporting of these data.
    Objective: To determine the frequency and use of racial and ethnic data in the ophthalmology literature in 2019.
    Design, Setting, and Participants: This cross-sectional study included all full-length human studies published between January and December 2019 in the American Journal of Ophthalmology, JAMA Ophthalmology, and Ophthalmology.
    Main Outcomes and Measures: Whether race or ethnicity was included in the data or analysis, how the categorization was described in the methods and results, specific racial and ethnic categories used, and whether and how the categories were determined.
    Results: A total of 547 articles were identified during the study period, 484 (88% ± 2.7%) of which reported background demographic information, including patient age and sex. Only 233 (43% ± 4.1%) reported race and/or ethnicity. Of those articles, 72 (31% ± 5.9%) categorized it as race, 51 (22% ± 5.3%) ethnicity, 56 (24% ± 5.4%) race/ethnicity, 21 (9% ± 3.7%) race and ethnicity, 12 (5% ± 3.0%) descent, 12 (5% ± 2.9%) population, and 5 (2% ± 2.0%) ancestry; in 21 (9% ± 3.8%) it was not defined. Only 30 studies (13% ± 4.4%) described how it was determined in the methods or results, most frequently by self-report (77% ± 3.9%). A total of 78 races and/or ethnicities were defined.
    Conclusions and Relevance: While most articles during the study period reported background demographic information, few included race and ethnicity and only a fraction of those described how these data were determined. The categories used were heterogeneous and often inconsistent. These findings suggest the need for increased and more standardized reporting of ethnic and racial demographic data in the ophthalmology literature.
    DOI:  https://doi.org/10.1001/jamaophthalmol.2020.2107
  19. J Surg Educ. 2020 Jun 16. pii: S1931-7204(20)30136-7. [Epub ahead of print]
       BACKGROUND: The academic productivity of an integrated plastic surgery applicant is strongly considered during the ranking process but is often difficult to assess. The h-index is a tool that provides an objective measure of both the quality and impact of an author's academic works. The goals of this study were to assess whether the h-index of recently matched plastic surgery interns correlates with their home and eventual residency program characteristics.
    METHODS: A database of all 2018 interns in integrated plastic surgery programs was created. The SCOPUS database was queried for the h-indices for each individual.
    RESULTS: In 2018, 77 integrated plastic surgery programs offered a total of 168 PGY1 positions; data was able to be obtained for 131 individuals. The mean h-index was 1.26 (range 0-14), with a mean of 4.22 publications (range 0-58). The h-index increased in concordance with overall number of publications. The h-index of applicants matching at Top 50 NIH Funded institutions had a significantly higher h-index (1.57) compared to those that matched to all other institutions (0.76) (p<0.05). Applicants matching at a "top 20" program as determined by Doximity reputation rankings also had a significantly higher h-index (1.96) compared to those matching at all other programs (0.83) (p< 0.05).
    CONCLUSIONS: The h-index of recently matched integrated plastic surgery interns correlates with several factors including program reputation and level of NIH funding. As applicants become increasingly well-qualified and the number of the publications increases commensurately, programs that place an emphasis on academic productivity may consider incorporating the h-index into their evaluation.
    Keywords:  Integrated plastic surgery; Publication; Residency match; h-Index
    DOI:  https://doi.org/10.1016/j.jsurg.2020.05.001
  20. Value Health. 2020 Jun;pii: S1098-3015(20)30088-7. [Epub ahead of print]23(6): 727-733
       OBJECTIVES: Health technology assessment aims to inform and support healthcare decision making, and trials are part of that process. The purpose of this study was to measure the impact of a sample of trials in a meaningful but robust fashion.
    METHODS: All randomized controlled trials funded and published by the UK National Institute of Health Research in the Health Technology Assessment journal series and other peer-reviewed journals were identified for 2006 to 2015. Citation analysis was performed for all trials, and quantitative content analysis was undertaken on a purposive sample to determine whether impact could be categorized as "instrumental" (ie, having a clear influence on key research and policy publications).
    RESULTS: The search identified 133 relevant trials. The citation rate per trial was 102.97. Of the 133 trials, 129 (98%) were cited in 1 or more systematic reviews or meta-analyses (mean per trial = 7.18, range = 0-44). Where they were cited, the trials were used in some form of synthesis 63% of the time. Ninety-one of the 133 (68%) trials were found to be cited in 1 or more guidance or policy document (mean per trial = 2.75, range = 0-26) and had an instrumental influence 41% of the time. The publication of these trials' results in journals other than the Health Technology Assessment journal appears to enhance the discoverability of the trial data. Altmetric.com proved to be very useful in identifying unique policy and guidance documents.
    CONCLUSION: These trials have impressive citation rates, and a sizeable proportion are certainly being used in key publications in a genuinely instrumental manner.
    Keywords:  health policy; impact; randomized controlled trials; systematic review
    DOI:  https://doi.org/10.1016/j.jval.2020.01.012
  21. Sci Adv. 2020 Jun;6(23): eaaz4868
      Previous research has found that funding disparities are driven by applications' final impact scores and that only a portion of the black/white funding gap can be explained by bibliometrics and topic choice. Using National Institutes of Health R01 applications for council years 2014-2016, we examine assigned reviewers' preliminary overall impact and criterion scores to evaluate whether racial disparities in impact scores can be explained by application and applicant characteristics. We hypothesize that differences in commensuration-the process of combining criterion scores into overall impact scores-disadvantage black applicants. Using multilevel models and matching on key variables including career stage, gender, and area of science, we find little evidence for racial disparities emerging in the process of combining preliminary criterion scores into preliminary overall impact scores. Instead, preliminary criterion scores fully account for racial disparities-yet do not explain all of the variability-in preliminary overall impact scores.
    DOI:  https://doi.org/10.1126/sciadv.aaz4868
  22. OTO Open. 2020 Apr-Jun;4(2):4(2): 2473974X20932497
      This study examines associations among publication number, National Institutes of Health (NIH) funding rank, medical school research rank, and otolaryngology department ranks of otolaryngology applicants during the 2018-2019 match cycle. Information regarding 2018-2019 otolaryngology applicants was collected from Otomatch.com and verified via department websites. Information was also collected regarding 2018 NIH funding rank and 2020 US News & World Report research rank of medical schools and otolaryngology departments. T tests and chi-square analyses were performed. Top 40 NIH funding rank, top 40 medical school research rank, and home institution department rank were separately associated with more publications and higher rates of matching into highly reputed otolaryngology departments (all P < .01). Furthermore, applicants who matched into ranked otolaryngology departments averaged significantly more publications (P < .01). Prospective otolaryngology applicants should take into account NIH funding rank, medical school research rank, and otolaryngology department rank, as they are associated with matching into high-ranking institutions.
    Keywords:  NIH funding; department rank; otolaryngology match; publication number
    DOI:  https://doi.org/10.1177/2473974X20932497
  23. JMIR Med Inform. 2020 Jun 16. 8(6): e16739
       BACKGROUND: Drug development is still a costly and time-consuming process with a low rate of success. Drug repurposing (DR) has attracted significant attention because of its significant advantages over traditional approaches in terms of development time, cost, and safety. Entitymetrics, defined as bibliometric indicators based on biomedical entities (eg, diseases, drugs, and genes) studied in the biomedical literature, make it possible for researchers to measure knowledge evolution and the transfer of drug research.
    OBJECTIVE: The purpose of this study was to understand DR from the perspective of biomedical entities (diseases, drugs, and genes) and their evolution.
    METHODS: In the work reported in this paper, we extended the bibliometric indicators of biomedical entities mentioned in PubMed to detect potential patterns of biomedical entities in various phases of drug research and investigate the factors driving DR. We used aspirin (acetylsalicylic acid) as the subject of the study since it can be repurposed for many applications. We propose 4 easy, transparent measures based on entitymetrics to investigate DR for aspirin: Popularity Index (P1), Promising Index (P2), Prestige Index (P3), and Collaboration Index (CI).
    RESULTS: We found that the maxima of P1, P3, and CI are closely associated with the different repurposing phases of aspirin. These metrics enabled us to observe the way in which biomedical entities interacted with the drug during the various phases of DR and to analyze the potential driving factors for DR at the entity level. P1 and CI were indicative of the dynamic trends of a specific biomedical entity over a long time period, while P2 was more sensitive to immediate changes. P3 reflected the early signs of the practical value of biomedical entities and could be valuable for tracking the research frontiers of a drug.
    CONCLUSIONS: In-depth studies of side effects and mechanisms, fierce market competition, and advanced life science technologies are driving factors for DR. This study showcases the way in which researchers can examine the evolution of DR using entitymetrics, an approach that can be valuable for enhancing decision making in the field of drug discovery and development.
    Keywords:  acetylsalicylic acid; aspirin; bibliometrics; biomedical entities; drug repurposing; entitymetrics
    DOI:  https://doi.org/10.2196/16739
  24. Ann Med Surg (Lond). 2020 Jul;55 260-264
       Background: Recent studies have reported a gender and medical degree disparity for those receiving Research Project Grants in surgical specialties. The aim of the present study is to analyze factors among academics neurosurgeons that correlate to higher amounts of R01 grant monies awarded.
    Materials and methods: The National Institutes of Health Research Portfolio Online Reporting Tools Expenditures and Results database was queried for neurosurgery funding between 2008 and 2018. Grant recipients were categorized among type of degree, secondary degree(s), professorship, gender, and h - index. Statistical analysis was performed.
    Results: The National Institutes of Health awarded 480 R01 grants totaling $182,482,644 to 81 allopathic neurosurgeons between 2008 and 2018. No osteopathic neurosurgeons were awarded an R01 grant during this timeframe. There was a significant difference for type of professorship on the total awarded amount at the p < 0.05 level for the three types of professorship [F (2,78) = 4.85, p < 0.01)]. There was a significant difference for magnitude of h - index on total R01 monies (p < 0.00001). Males accounted for the majority of R01 monies (93.99%); however, no significant difference between average amount awarded and gender was identified (p = 0.86). A secondary degree was without significant difference for R01 amount awarded (p = 0.75).
    Conclusions: The present study establishes a medical degree disparity for academic neurosurgeons who receive an R01 grant. Statistically significant factors found to affect amount of R01 grant monies awarded were limited to type of professorship and magnitude of h - index.
    Keywords:  Academic medicine; Allopathic physician; DO, Doctor of Osteopathic medicine; MA, Master of Arts; MBA, Master of Business Administration; MD, Doctor of Allopathic medicine; MHS, Master of Health Science; MPH, Master of Public Health; MS, Master of Science; Medical education; NIH, National Institutes of Health; Neurosurgery; Osteopathic physician; PhD, Doctor of Philosophy; R01, Research Project Grant
    DOI:  https://doi.org/10.1016/j.amsu.2020.06.002
  25. Gac Sanit. 2020 Jun 16. pii: S0213-9111(20)30122-9. [Epub ahead of print]
      
    DOI:  https://doi.org/10.1016/j.gaceta.2020.03.007
  26. Curr Probl Diagn Radiol. 2020 May 17. pii: S0363-0188(20)30096-7. [Epub ahead of print]
       PURPOSE: To analyse the demographics, academic background, and scholarly activity of Interventional Neuroradiology (INR)/Endovascular Surgical Neuroradiology (ESN) program directors (PDs) in the United States (US) and Canada.
    METHODS: A list of all INR/ESN fellowships was obtained from the Accreditation Council for Graduate Medical Education, the Committee on Advanced Subspecialty Training, maintained by Society of Neurological Surgeons, the NeuroInterventional Training list website maintained by the Society of NeuroInterventional Surgery, and the Neurosurgical Fellowship Training Program Directory website maintained by the American Association of Neurological Surgeons. Online search was performed to identify PDs for these programs. Publicly available sources used to gather information about each PD included the program websites, the HealthGrades and Doximity websites, and Elsevier's Scopus database. Demographic and educational data including age, gender, educational background, subspecialty, appointment age, interval between residency completion and appointment as PD, additional degrees, academic rank, prior leadership positions, and metrics of scholarly activity were recorded. One-way analysis of variance was used to determine differences between the means of different groups.
    RESULTS: A total of 78 PDs from 72 programs were included, of which 72 (92.3%) were male with the mean age of 49.59 years (SD 7.25). Specialty division of PDs was neurosurgery (40, 51.3%), radiology (26, 33.3%), and neurology (10, 12.8%), whereas 2 PDs were dual board-certified in neurology and radiology. Twenty-five (32.1%) PDs attended an international medical school. All PDs received an MD degree or foreign equivalent, with no PD holding a DO degree. Eleven PDs received a PhD degree and 16 PDs received fellowship from a professional medical society. The mean ± SD publications, citations, and h-indexes of PDs were 111.32 ± 121.18, 2985.0 ± 1459.0 and 22.27 ± 15.45, respectively. There was no statistical difference in scholarly activity among PDs when stratified on the basis of specialty, gender, and US region.
    CONCLUSION: INR/ESN PDs are predominantly male, with a majority from neurosurgery background, and thirty percent having graduated from international medical schools.
    DOI:  https://doi.org/10.1067/j.cpradiol.2020.05.001
  27. Cureus. 2020 May 17. 12(5): e8170
       INTRODUCTION: Limited data currently exist regarding the demographics of principal investigators (PIs) in obstetrics and gynecology (OBGYN), who have received an R01 grant from the National Institutes of Health (NIH).
    OBJECTIVE: This study investigated funding differences among gender and advanced degree for PIs in the disciplines of OBGYN.
    METHODS: Retrospective data were collected from the NIH Research Portfolio Online Reporting Tools Expenditures and Results (RePORTER) tool to identify OBGYN PIs who received an R01 grant between 2008 and 2017.  Results: Between 2008 and 2017, the NIH awarded 263 R01 grants totaling $113,326,883 in funding to investigators in OBGYN. Male PIs and PIs holding a non-medical degree were awarded the majority of R01 grants (52.47% and 55.51%, respectively). Zero osteopathic (Doctor of Osteopathic Medicine [DO]) physicians were awarded an R01 grant in OBGYN during this time period. Females were awarded larger dollar amounts than males ($449,556 vs $414,003, p=0.04). Allopathic (Doctor of Medicine [MD]) physicians were awarded larger grants than scientists holding a non-medical degree ($467,849 vs $401,291, p<0.01). Both male and female MD physicians were awarded more dollars per grant as compared with PIs holding a non-medical degree (p=0.01 and p<0.01, respectively).
    CONCLUSIONS: Between 2008 and 2017, a degree disparity was found to exist for investigators who received an NIH R01 grant in OBGYN. Females and investigators holding an MD degree were awarded larger total grants than their male and non-physician counterparts. Further research needs to be undertaken to understand the degree disparity and recent funding trends by the NIH.
    Keywords:  obgyn; osteopathic; r01
    DOI:  https://doi.org/10.7759/cureus.8170
  28. J Clin Epidemiol. 2020 Jun 16. pii: S0895-4356(20)30189-X. [Epub ahead of print]
       OBJECTIVES: To assess female representation in primary studies underpinning recommendations from clinical guidelines and systematic reviews for sepsis treatment in adults.
    STUDY DESIGN AND SETTING: We conducted a bibliometric study.. We removed studies pertaining to sex-specific diseases and included quasi-randomised, randomised clinical trials (RCTs), and observational studies. We analysed the female participation-to-prevalence ratio (PPR).
    RESULTS: We included 277 studies published between 1973 and 2017. For the 246 studies for which sex data were available, the share of female participation was 40%. Females overall were underrepresented relative to their share of the sepsis population (PPR 0.78). Disaggregated results were reported by sex in 57 studies. In univariate analyses, non-ICU setting and consideration of other social health determinants were significantly associated with greater female participation (P<0.001 and P=0.023, respectively). In regression models, studies published in 1996 or later were likely to report sex, whilst RCTs were unlikely to do so (P=0.019 and P<0.001, respectively).
    CONCLUSION: Our study points to female underenrolment in sepsis studies. Primary studies underpinning recommendations for sepsis have poorly reported their findings by sex.
    Keywords:  Clinical guidelines; Gender; Participation-to-prevalence ratio; Sepsis; Sex; Sex-related reporting; Systematic reviews
    DOI:  https://doi.org/10.1016/j.jclinepi.2020.06.014
  29. Int J Environ Res Public Health. 2020 Jun 17. pii: E4354. [Epub ahead of print]17(12):
      The objective of this study was to reveal RULA method applications in terms of the knowledge, country, year and journal categories. The search was performed using the "Web of Science Core Collection". The period from 1993 to April 2019 was selected. Eight hundred nine results were obtained, of which 226 were used. The largest number of publications was determined to be in the fields of industry and health and social assistance, which coincides with the OWAS and Standardized Nordic Questionnaire methods. By country, the USA stands out for its greater number of research studies and categories that are encompassed. By date, 2016 was the year when more studies were carried out, again coinciding with the Standardized Nordic Questionnaire. By journal, "Work-A Journal of Prevention Assessment and Rehabilitation" is highlighted, as it is for the REBA method as well. It was concluded that RULA can be applied to workers in different fields, usually in combination with other methods, while technological advancement provides benefits for its application.
    Keywords:  RULA; applications; biomechanics; ergonomics; musculoskeletal disorders
    DOI:  https://doi.org/10.3390/ijerph17124354