bims-evares Biomed News
on Evaluation of research
Issue of 2022‒10‒30
79 papers selected by
Thomas Krichel
Open Library Society


  1. Scientometrics. 2022 Oct 17. 1-7
      Climate change and global warming have attracted more and more attention from countries all over the world. A recent study published in Scientometrics has evaluated the changing dynamics of climate change-related research publications via a bibliometric analysis and further probed the relationship between climate change-related research output and carbon dioxide emissions. We try to re-evaluate the bibliometric analysis section of the mentioned study and provide three improvement suggestions related to data source, search field and search query respectively. Besides, some new explanations have also been offered for the abnormal increase of research outputs indexed by Web of Science Core Collection in specific years such as 1991. These suggestions and explanations will provide important references for future various bibliometric analyses and research evaluation.
    Keywords:  Bibliometric analysis; Research evaluation; Topic search; Web of Science Core Collection
    DOI:  https://doi.org/10.1007/s11192-022-04540-1
  2. Front Oncol. 2022 ;12 955259
      Background: Small-cell lung cancer (SCLC) is a recalcitrant tumor with a poor prognosis. With the rise of SCLC research in the past decade, this study aims to analyze the foundation and frontiers of SCLC research through bibliometric analysis.Methods: Relevant publications from the Web of Science Core Collection were retrieved on January 3, 2022. R package bibliometrix and EXCEL2019 were used to analyze quantitative variables. Bibliometric mapping was constructed by VOS viewer and CiteSpace software to visualize citation, co-authorship, co-occurrence, and co-citation analysis of countries/regions, organizations, authors, references, and keywords.
    Results: A total of 2,361 publications related to SCLC were identified with the total amount of articles steadily increasing, where China is the most productive country with 859 papers. Scholars and organizations from the United States, China, and Europe are primary sources of this research, among which the University of Texas MD Anderson Cancer Center made the most contribution to the field with 122 papers. Lung Cancer published the highest number of SCLC-related articles with a total of 121, while the Journal of Thoracic Oncology received the most citations totaling 3,098. Rudin, Charles M., and Sage, Julien are the most creative author. Leora, Horn, 2018, New Engl J Med and Rudin, Charles M., Nat Genet, 2012 can be categorized as classic literature owing to their high citations or strong sigma value. "Heterogeneity & Subtypes" and "Immunotherapy" may be the new frontiers in the SCLC domain.
    Conclusion: Research on SCLC showed an upward trend based on the current global situation. Moreover, the current scope of collaboration in SCLC research is chiefly regional, which should further focus on transnational cooperation in the future. More attention should be devoted to "Heterogeneity & Subtypes" and "Immunotherapy", which will be the hotspots in future research.
    Keywords:  bibliometric analysis; hot spots; immunotherapy; research trends; small cell lung cancer
    DOI:  https://doi.org/10.3389/fonc.2022.955259
  3. Front Public Health. 2022 ;10 1020231
      Background: IgA vasculitis Nephritis (IgAVN) is a kidney-damaging disease that occurs during the course of IgA vasculitis (IgAV) and is the most serious complication of IgAV. However, there is a lack of reports of bibliometric analysis of IgAVN in children. The purpose of this study is to conduct a bibliometric analysis of IgAVN in children from 2000 to 2022, to explore the current status and cutting-edge trends in the field of IgAVN in children, and to establish new directions for subsequent research.Methods: Screening the literature in the field of IgAVN in children in the Web of Science Core Collection (WoSCC) from 2000 to 2022. Visual analysis of their annual publications, countries, institutions, authors, journals, keywords, and references were using CiteSpace5.8.R3 and VOSviewer1.6.18.
    Results: A total of 623 publications were included in the study, since the beginning of 2014, there has been an overall increasing trend in the number of articles issued. The most prolific country and institution were China and Zhejiang University. The most frequently cited author was Coppo R, with 331 citations, who has made great contributions to IgAVN. Mao Jianhua, Lee JS and Wyatt Robert J were the most prolific authors, all with 9 articles. Pediatric Nephrology was the most published and cited journal. The highest burst strength keyword is IgA vasculitis, and the highest burst strength reference is Davin JC, 2014.
    Conclusion: The research hotspots and trends predicted by the analysis of this study provide a reference for in-depth research in this field with a view to promoting the development of IgAVN research in children.
    Keywords:  CiteSpace; IgA vasculitis nephritis; VOSviewer; bibliometric analysis; web of science
    DOI:  https://doi.org/10.3389/fpubh.2022.1020231
  4. Evid Based Complement Alternat Med. 2022 ;2022 1989401
      Background: Acupuncture has been confirmed as a suitable therapy for treating polycystic ovary syndrome (PCOS). However, there is no bibliometric analysis of the global use of acupuncture for PCOS. Our study used CiteSpace (5.8.R3) to provide a profile of the current state and trends in this field.Methods: Articles regarding acupuncture therapy for treating PCOS were retrieved from the Web of Science Core Collection. CiteSpace was used to analyze the number of publications, countries, institutions, journals, authors, cited references, and keywords by using standard bibliometric indicators.
    Results: A total of 159 publications were considered for the final analysis. The number of publications has slowly increased with fluctuations between years, and the most active countries, institutions, journals, and authors concerning acupuncture therapy for PCOS were identified. Evidence-Based Complementary and Alternative Medicine was the most productive journal, and Fertil Steril was the most cited. China and Heilongjiang University of Chinese Medicine were considered the most prolific countries and institutions in this field, respectively. Elisabet Stener Victorin became the most influential author and most cited author. Jedel E. published the most cited article. "Polycystic ovary syndrome" was the most frequent keyword, and the top three frontiers mentioned were research method, intervention, and outcome.
    Conclusion: The current status and trends in clinical research of acupuncture therapy on PCOS patients are revealed according to the results of this bibliometric study, which may facilitate researchers to identify hot topics and new directions for future study in this field.
    DOI:  https://doi.org/10.1155/2022/1989401
  5. Front Surg. 2022 ;9 1019985
      Background: Sarcopenia in geriatric hip fractures is attracting increased attention in recent years. This study aimed to explore the bibliometric characteristics and current status of sarcopenia research in hip fractures of older patients.Methods: Publications related to sarcopenia in geriatric hip fracture published between January 2000 and July 2022 were extracted from the Science Citation Index Expanded, and bibliometric and visualized studies were performed by VOSviewer, Citespace, and R.
    Results: The 1,223 articles used in our study were written by 6,326 authors from 1,879 organizations in 60 countries, published in 388 journals, and cited 37,198 references from 5,422 journals. The United States contributed the most publications (288 publications). The journal with the largest number of papers was Osteoporosis International (62 publications), and the Journals of Gerontology Series A - Biological Sciences and Medical Sciences had been more cited than any other journals in this field (3,302 citations). The University of Melbourne published the biggest number of papers (72 publications) focusing on sarcopenia in geriatric hip fractures while the California Pacific Medical Center Research Institute had the largest citations (4,239 citations). Cawthon PM was the most productive and influential author in the field. keywords were classified into 6 clusters: Cluster 1 (sarcopenia in aging), Cluster 2 (osteoporosis), Cluster 3 (bone density), Cluster 4 (body composition), Cluster 5 (physical performance), and Cluster 6 (risk factor).
    Conclusion: Geriatric hip fracture is one of the most significant health issues in the aging society. In the past 20 years, an increasing number of studies were performed to explore the relationship between sarcopenia and hip fracture in older adults. The United States showed the strongest influence in this field, including publication numbers, citations, institutions, funding agencies, and authorship. Sarcopenia in aging, osteoporosis, bone density, body composition, physical performance, and risk factors may become the future hotspots in this field.
    Keywords:  bibliometric study; elderly; hip fracture; sarcopenia; visualized study
    DOI:  https://doi.org/10.3389/fsurg.2022.1019985
  6. Front Neurol. 2022 ;13 991099
      Background: Over the past decade, numerous advances have been made in the research on electrical stimulation of skeletal muscle. However, the developing status and future direction of this field remain unclear. This study aims to visualize the evolution and summarize global research hot topics and trends based on quantitative and qualitative evidence from bibliometrics.Methods: Literature search was based on the Web of Science Core Collection (WoSCC) database from 2011 to 2021. CiteSpace and VOSviewer, typical bibliometric tools, were used to perform analysis and visualization.
    Results: A total of 3,059 documents were identified. The number of literature is on the rise in general. Worldwide, researchers come primarily from North America and Europe, represented by the USA, France, Switzerland, and Canada. The Udice French Research Universities is the most published affiliation. Millet GY and Maffiuletti NA are the most prolific and the most co-cited authors, respectively. Plos One is the most popular journal, and the Journal of Applied Physiology is the top co-cited journal. The main keywords are muscle fatigue, neuromuscular electrical stimulation, spinal cord injury, tissue engineering, and atrophy. Moreover, this study systematically described the hotspots in this field.
    Conclusion: As the first bibliometric analysis of electrical stimulation of skeletal muscle research over the past decade, this study can help scholars recognize hot topics and trends and provide a reference for further exploration in this field.
    Keywords:  bibliometric analysis; electrical stimulation; network analysis; skeletal muscle; visualization
    DOI:  https://doi.org/10.3389/fneur.2022.991099
  7. Environ Sci Pollut Res Int. 2022 Oct 24.
      The concept of resilience is widely used in many specific fields, such as energy. Energy resilience is receiving increasing scientific attention. In the long-term sustainable development of society, energy and resilience policies are the key strategies to achieve international development goals. This paper analyzes the existing energy resilience literature and presents the research hot spots and trends. After extracting 4887 articles from the Science Citation Index Expanded and Social Sciences Citation Index databases, this paper takes the literature data during 1985-2021 through topic search using the keywords of energy resilience and applies bibliometrics to study the development traits of the field. The primary research purposes are to discover the knowledge framework of energy resilience, together with a review of integral development trends, elementary publication characteristics, and an analysis of related leading journals. Aside from analyzing the number of publications, citations, and cooperation types, this study identifies the most prolific researchers from the country-level, institution-level, and author-level in this area, thus providing a longitudinal overview of the dynamic research evolution of energy resilience and the knowledge spread locus in this domain.
    Keywords:  Bibliometric; Energy Resilience; Main path analysis; Strategy diagram
    DOI:  https://doi.org/10.1007/s11356-022-23768-1
  8. Medicine (Baltimore). 2022 Oct 21. 101(42): e31179
      DESIGN: This is a bibliometric analysis. Performed by Scientific Mapping technique. The purpose of the study is to analyze articles on Kyphoplasty. Kyphoplasty is a minimally invasive surgical method. Bibliometrics is the mathematical and statistical quantitative analysis of works. One of the primary uses of bibliometric analysis is scientific mapping.METHOD: To conduct the bibliometric analysis of the subject of Kyphoplasty, the Web of Science Core Collection database was preferred. After the selection of the data set, the data were filtered; as a result, the study was carried out on 2236 articles. Researchers, journals, articles, institutions, and the studies' countries were analyzed.
    RESULTS: According to the number of articles published in Kyphoplasty, China, USA, Germany, Korea, and Italy are among the leading countries. According to the analysis, the authors with the highest h-index value are Yang HL and Hirsch JA. The European Spine Journal and the Spine are the most impactful journals.
    CONCLUSIONS: Our study was carried out with the Science Mapping technique using Bibliometrics software. This type of work has become popular in recent years. Such studies are not common in the field of neurosurgery.
    DOI:  https://doi.org/10.1097/MD.0000000000031179
  9. Aesthetic Plast Surg. 2022 Oct 25.
      BACKGROUND: The number of patients undergoing buttock augmentation surgery has increased rapidly with time, changes in people's aesthetic perceptions, and the increased concern for their shape. The number of publications regarding buttock augmentation has also continued to increase. However, no bibliometric analysis concerning buttock augmentation has been published. This study aimed to provide a qualitative and quantitative evaluation of buttock augmentation-related publications using bibliometric analysis and information on research hotspots and trends in this field.METHODS: The buttock augmentation-related publications published between 1999 and 2021 were extracted from the Web of Science Core Collection (WOSCC) database for analysis. The data were analysed and presented using VOSviewer and Microsoft Excel.
    RESULTS: There were 492 articles in the (WOSCC) database, including 442 (89.84%) original research articles, with the number of publications increasing each year. The USA (208 publications, 42.28%) is the leading contributor in this field and has a high academic reputation. The most productive and co-cited journal on this subject is "Plastic and Reconstructive Surgery" (66 publications, 13.41%, 2200 citations). Cardenas-Camarena (9 publications, 1.83%, 158 citations) was the most published and co-cited author. Research hotspots include the following three topics: experience and technology of buttock augmentation, autologous fat buttock augmentation and its safety, and buttock aesthetics study. There will be more publications in the future, and research trends will focus on silicone implants, safety, satisfaction, and autologous fat grafting.
    CONCLUSION: Buttock augmentation research is rapidly evolving, and this study provides a perspective view of buttock augmentation research in Plastic and Reconstructive Surgery.
    LEVEL OF EVIDENCE III: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
    Keywords:  Autologous fat grafting; Bibliometric analysis; Buttock aesthetics; Buttock augmentation; Buttock implant; Gluteoplasty
    DOI:  https://doi.org/10.1007/s00266-022-03140-x
  10. Nutrients. 2022 Oct 14. pii: 4288. [Epub ahead of print]14(20):
      Numerous studies have covered exercise-induced muscle damage (EIMD) topics, ranging from nutritional strategies to recovery methods, but few attempts have adequately explored and analyzed large volumes of scientific output. The purpose of this study was to assess the scientific output and research activity regarding EIMD and protein intake by conducting a bibliometric and visual analysis. Relevant publications from 1975-2022 were retrieved from the Web of Science Core Collection database. Quantitative and qualitative variables were collected, including the number of publications and citations, H-indexes, journals of citation reports, co-authorship, co-citation, and the co-occurrence of keywords. There were 351 total publications, with the number of annual publications steadily increasing. The United States has the highest total number of publications (26.21% of total publications, centrality 0.44). Institutional cooperation is mostly geographically limited, with few transnational cooperation links. EIMD and protein intake research is concentrated in high-quality journals in the disciplines of Sport Science, Physiology, Nutrition, and Biochemistry & Molecular Biology. The top ten journals in the number of publications are mostly high-quality printed journals, and the top ten journals in centrality have an average impact factor of 13.845. The findings of the co-citation clusters and major keyword co-occurrence reveal that the most discussed research topics are "exercise mode", "nutritional strategies", "beneficial outcomes", and "proposed mechanisms". Finally, we identified the following research frontiers and research directions: developing a comprehensive understanding of new exercise or training models, nutritional strategies, and recovery techniques to alleviate EIMD symptoms and accelerate recovery; applying the concept of hormesis in EIMD to induce muscle hypertrophy; and investigating the underlying mechanisms of muscle fiber and membrane damage.
    Keywords:  bibliometric analysis; delayed-onset muscle soreness; eccentric exercise; inflammation; muscle damage; nutritional strategy; performance; protein intake
    DOI:  https://doi.org/10.3390/nu14204288
  11. J Perinat Med. 2022 Oct 31.
      OBJECTIVES: To apply scientometric methodology to characterize influential articles in the Journal of Perinatal Medicine (JPM).METHODS: We performed a cross-sectional study of all JPM articles indexed in Clarivate Web of Science (WOS), NIH Open Citation Collection, and Altmetric Explorer databases (1973-2022). We identified articles cited ≥100 times in WOS and articles with highest Relative Citation Ratios (RCR, a metric of influence based on citations) and highest Altmetric Attention Scores (AAS, a metric of engagement with social media and public platforms). We performed descriptive analysis to characterize influential articles based on citation rates vs. highest AAS, and quantile regression with bootstrapping to estimate the median differences (95% confidence intervals).
    RESULTS: We identified 4095 JPM articles that were indexed in the WOS, of which 3,959 (96.7%) had RCRs and 939 (22.9%) had AASs. The study cohort included 34 articles cited ≥100 times and the 34 top-RCR and 34 top-AAS articles, representing 83 unique articles. These influential articles had median 67 citations (IQR 17-114), median RCR 3.4 (IQR 1.7-5.0), and median AAS 14 (IQR 3-28). The majority were observational studies and reviews. Compared to top-AAS articles, top-cited articles had higher median citations (117 [IQR 111-147] vs. 13 [IQR 5-62]; median difference 104.0, 95% CI 86.6-121.4) and citations per year (7.3 [IQR 4.9-10.6] vs. 2.3 [0.7-4.6]; median difference 5.5 [95% CI 3.1-7.9]). Results were similar for top-RCR vs. top-AAS articles.
    CONCLUSIONS: We identified influential articles during 50 years of JPM, providing insight into the impact of the journal and providing a template for future studies of academic journals.
    Keywords:  altmetric attention score; bibliometrics; citation analysis; relative citation ratio; scientometrics
    DOI:  https://doi.org/10.1515/jpm-2022-0461
  12. Risk Anal. 2022 Oct 28.
      As the decision-making basis for "safety" in risk management and risk assessment activities, acceptable risk has always been an important topic of risk-related research. Based on the records in the Science Citation Index Expanded database and Social Sciences Citation Index database via the Web of Science Core Collection, 1124 articles or reviews related to acceptable risk in engineering and operations research and management science were retrieved. These documents, published between 1961 and 2021, covered 3056 authors, 75 countries/territories, 1296 institutions, and 323 journals. In this study, bibliometric data such as annual growth trends were analyzed by using descriptive statistics. Through the co-occurrence maps created by CiteSpace and Gephi, the most productive and influential countries/territories, institutions, and authors as well as their cooperation networks were identified. Further analysis was conducted to determine the core publications and publication sources in this field through co-citation analysis. Insights into focus areas and research topics over time were obtained through keyword co-occurrence analysis. This study provides a macroscopic overview of acceptable risk research and may help researchers better understand this research field and predict its dynamic directions.
    Keywords:  CiteSpace; Gephi; acceptable risk; bibliometric analysis; quantitative risk assessment; safety
    DOI:  https://doi.org/10.1111/risa.14049
  13. Eur J Med Chem. 2022 Oct 14. pii: S0223-5234(22)00740-1. [Epub ahead of print]244 114838
      Proteolysis targeting chimera (PROTAC) technology, one of the targeted protein degradation technologies, has drawn marked attention from researchers of both academia and industry in recent years. After over two decades of development, the literature on it has proliferated. In order to better grasp the frontiers and hot spots of PROTAC, this bibliometric analysis was carried out. The articles and reviews regarding PROTAC were culled from the Web of Science Core Collection. General information and the trend of publication outputs, countries/regions, authors, journals, influential papers, and keywords in this field were visually analyzed using CtieSpace, VOSviewer, or Excel software. As a result, a total of 808 publications were included. The number of papers regarding PROTAC significantly increased yearly. These papers mainly come from 45 countries/regions led by the USA and China. 3886 authors were identified participating in these studies, among which Craig M. Crews had the most significant number and influential articles. Journal of Medicinal Chemistry and European Journal of Medicinal Chemistry are the two journals with the most papers. After analysis, the most influential papers were identified in the area, including highly cited papers, references with citation burst, and high co-citated papers. The most common keywords including cancer, E3 ligase, drug discovery, epigenetic, resistance, and so on, represent the current and developing areas of study. BRDs, androgen receptor (AR), HDACs, estrogen receptor (ER), EGFR, CDKs, and KRAS are the most common targets. At last, frontiers and challenges of PROTAC were discussed through the bibliometric analysis. This paper will be helpful for better understanding the frontiers and hotspots of PROTAC.
    Keywords:  Bibliometric; Cancer; CiteSpace; Proteolysis targeting chimera (PROTAC); VOSviewer
    DOI:  https://doi.org/10.1016/j.ejmech.2022.114838
  14. Cureus. 2022 Sep;14(9): e29331
      The current paper explores the mutual impact of psychological factors and cardiac surgery on each other using bibliometric analysis with the help of indicative cited publications, co-cited journals, and collaborations between countries, institutions, and authors. Citation analysis is an attractive methodology because it provides quantitative information that is readily acquired with electronic databases and that can be compared across topic areas. The bibliometric investigation was done using the PubMed database, Scopus, Web of Science, etc. with the help of appropriate MeSH words. Followed by an analysis of data with the help of CiteSpace 5.3.R4, Microsoft Excel 2016, and IBM SPSS Statistics 20.0 software (IBM Corp., Armonk, NY). The software extracts the number of scientific publications, citation frequency, and keyword trends. Relational figures and tables were obtained for data interpretation. The records of 259 articles were analyzed using bibliometric investigation which shows the increasing incidence of psychological consequences linked with coronary artery bypass grafting (CABG) surgery. This indicates that immediate management is required to overcome this. The present bibliometric study emphasizes the need for psychological screening and management of post-CABG patients. This will lay the path for organizing and prioritizing future research on vascular psychiatry and its early management.
    Keywords:  anxiety; bibliometric analysis; coronary artery bypass graft; depression; psychological factors; vascular psychiatry
    DOI:  https://doi.org/10.7759/cureus.29331
  15. Healthcare (Basel). 2022 Oct 03. pii: 1941. [Epub ahead of print]10(10):
      Premature mortality is defined as death that occurs before the average age of death for a particular population. Although premature mortality is a public health problem globally, the literature indicates no bibliometric studies that have made a holistic evaluation of the publications on this issue. This study aims to explore the characteristics of the publications on premature mortality in terms of the number of publications, citations, countries, collaboration, and the author's productivity and to further identify the trending keyword and relevant research topics. All the articles related to premature mortality data were retrieved from the Web of Science (WOS) database using the search terms "premature death," "premature mortality," or "years of life loss." The retrieved articles were downloaded in a BibTeX format file. A Bibliometrix package from R software was used to perform bibliometric analyses. A total of 1060 original research articles and reviews have been published since 1971, with a total of 5499 contributing authors. The number of publications has increased substantially in the past decade. The annual percentage growth rate of publications is 5.08%. The United States is the leading country in this area of research with the highest number of publications (n = 280), the highest total citation (17,378), and the most activity in collaboration. Our thematic map suggests that the cluster for cardiovascular disease became the main research domain in this field, while the cluster for air pollution is an important topic for future research. Additionally, neurodegeneration is another cluster of research that should be developed further and connected with premature mortality. These bibliometric findings hopefully will help scholars better understand the global overview of premature mortality and provide information for potential collaborators, with the information promising attractive areas for future research.
    Keywords:  bibliometric; premature mortality; research productivity; thematic map; trending keywords
    DOI:  https://doi.org/10.3390/healthcare10101941
  16. J Clin Med. 2022 Oct 11. pii: 5987. [Epub ahead of print]11(20):
      The literature on the COVID-19 landscape has rapidly expanded in the pandemic period. The current study undertakes a bibliometric analysis of research in the topic of the clinical and laboratory characteristics of pediatric COVID-19 cases. Our aim is to perform a comprehensive bibliometric review of current research trends and patterns of this research domain. Publications retrieved from the Web of Science Core Collection and VOSviewer were used for analysis and network visualization. We analyzed geographical distribution and temporal trends, collaboration and citation patterns of authors, institutions, and countries, and core research themes from co-occurrence of keywords and terms. The analysis showed that contributions in the research field were from 302 publications, 1104 institutions, 62 countries, and 172 journals. Many publications were authored by American and Chinese authors, and many were published in the Pediatric Infectious Disease Journal, Pediatric Pulmonology, and Frontiers in Pediatrics. The top cited and co-cited journals were the New England Journal of Medicine, Nature, JAMA, Lancet Infectious Diseases, and BMJ. The network visualization maps of keywords and terms offered a global overview of the clinical and laboratory characteristics of pediatric COVID-19 patients. The bibliometric profile of the researched domain, based on analyzing a large collection of publications/data, could (i) enrich the researchers and non-researchers understanding of the field existing patterns and trends, and (ii) be useful in clinical practice (diagnostic and management) and public health policy.
    Keywords:  COVID-19; VOSviewer; bibliometric; clinical; laboratory; symptoms
    DOI:  https://doi.org/10.3390/jcm11205987
  17. Int Wound J. 2022 Oct 23.
      Pathological scar is a classic problem in plastic and reconstructive surgery. Although the researches on pathological scar have been conducted for decades, the way to go to address this thorny problem still remains challenging. To the best of our knowledge, few bibliometric analysis concerning pathological scar have been reported. In this study, we set out to employ bibliometric and visual analysis to offer research status and trends of pathological scar over the period 2001-2021. All publications covering pathological scar during 2001-2021 were retrieved and extracted from the Web of Science database. We applied VOSviewer software to evaluate the keywords and research hotpots, and the online tool (http://bibliometric.com/) was used to carried out the publication trends analysis. A total of 2221 pathological scar-related articles were identified over the period 2001-2021. China is the country which had the largest volume of publications (819, 36.87%), followed by the United States (416, 18.73%), Japan (144, 6.48%), Korea (142, 6.39%), and England (118, 5.31%). Among the institutions and journals, Shanghai Jiao Tong University (167) and Wound Repair and Regeneration (85) accounted for the most papers related to pathological scar, respectively. Professor Bayat A, who had the most citation frequency (2303), made great contribution in pathological scar field. "Fibroblast", "expression", and "proliferation" were identified as the pathological scar research hotspot through analysis of the keywords. In terms of publication, China ranked first all over the world, but the numbers of publication are inconsistent with the citation frequency, ranking first and second, respectively. Shanghai Jiao Tong University and journal Wound Repair and Regeneration stand for the highest level of research in this field to a certain extent. In the early stage, the research focus was mainly on the prevention, treatment, and risk factors for recurrence of pathological scar from cases. In the later stage, the research focus was on the comprehensive management, in which the mechanism research was in-depth to the molecular and gene level.
    Keywords:  bibliometric analysis; hypertrophic scar; keloid; keywords; pathological scar; research hotspots
    DOI:  https://doi.org/10.1111/iwj.13988
  18. Nutrients. 2022 Oct 12. pii: 4262. [Epub ahead of print]14(20):
      Sarcopenia is age-related, pathophysiological muscle atrophy. Research regarding nutrition treatment of sarcopenia has developed rapidly, particularly as populations age. We evaluated the development of trends in this field using a bibliometric analysis. Articles up to July 2022 were searched in the Scopus database. Bibliographic information from the selected publications, such as countries, citations, world maps, institutions, authors, journals, and keywords, were converted and analyzed automatically using the "bibliometrix" package in R environment (version 4.2.0). We identified 368 Scopus articles from 1998-2021. According to citation analyses, 27 documents received more than 100 citations. Bibliometric analysis based on the literature included in this study revealed that South Korea (61 publications), United States (50), Japan (35), China (30), and Italy (20) contributed the most publications. Tehran University of Medical Science (19 records, 2.55% of articles) contributed the most publications. The most productive author was Landi, with eight articles (2.17% of articles). The publications were located in 196 journals, with Nutrients having the most publications (30, 8.15% of articles). The curves representing keywords "sarcopenia" and "aged" were the most apparent. Our analysis suggested that global nutrition and sarcopenia-related research increased rapidly from 2001 to 2021, demonstrating that this was a promising area of future research that could benefit from continued advances. Future research may focus on the effects of age and sex as well as intervention effectiveness, particularly exercise and nutrition supplementation.
    Keywords:  bibliometrics; nutrition; older people; quantitative analyses; sarcopenia
    DOI:  https://doi.org/10.3390/nu14204262
  19. Int J Stroke. 2022 Oct 26. 17474930221136704
      BACKGROUNDTwitter is a social media platform popularly used by health practitioners, a trend that has been followed by medical journals. The impact of Twitter in bibliometrics of stroke-related literature is yet to be determined.AIMSWe aimed to qualitatively assess the usage of Twitter by stroke journals and study the relationship between Twitter activity and citation rates of stroke articles.METHODSWe used Journal Citation Reports to identify stroke journals. We collected the 2021 Impact Factor (IF) and the top 50 articles contributing to each journal IF. Relevant metrics were collected through Twitonomy, Altmetric and Web of Science. The association between Twitter activity and citation rates was tested by a negative binomial regression model adjusted to journal's IF. A bivariate correlation and a log-linear regression model adjusted to journal's IF tested the relationship between number of tweets, tweeters and the number of citations.RESULTSWe collected 450 articles across 9 stroke-dedicated journals, five of which had a Twitter account. Only 95 (21%) articles had no Twitter mentions. The median number of citations in articles with versus without Twitter activity was 19 (10-39) vs 11(7-17) (P<0.001). Twitter activity was associated with higher citation rates controlling for the IF (OR: 2.7, 95%CI 2.12-3.38, P<0.001). We found number of tweets to be predicted by the number of citations controlling for the IF (B=0.33, 95%CI 0.29-0.40, β=0.54, P<0.001).CONCLUSIONSTweeted stroke articles tend to have higher citation rates which can be predicted by the number of tweets.
    Keywords:  Altmetrics; Citations; Impact Factor; Social Media; Stroke; Twitter
    DOI:  https://doi.org/10.1177/17474930221136704
  20. Front Oncol. 2022 ;12 1033683
      Malignant tumor is a disease caused by the imbalance of cell growth and proliferation mechanism, which seriously threatens human health and life safety. However, side effects and drug resistance are the key factors that limit the efficacy of anti-tumor drugs. Therefore, it is urgent and necessary to explore and unearth natural, safe and effective chemosensitizers in tumor researches. Curcumin is the main active ingredient in Curcuma, which has anti-inflammatory, anti-inflammatory and anti-oxidation effects, and has inhibitory effects on a variety of cancers. Bibliometric analysis is a scientific and quantitative method to assess the published articles, which can help researchers to find the development trends and the research hotspots of a specific research field, providing the development of future research for researchers. This study searched the Web Science Core Collection (woscc) for publications related to curcumin and tumors from January 1, 2001 to December 31, 2021. The specific characteristics of 1707 publications were analyzed by using Microsoft Excel software, CiteSpace, Vosviewer and online analysis platform of literature metrology. China had the largest number of published articles, with 579 publications. Aggarwal BB's articles total citations and average citations were the most. PLoS One had the largest number of publications, with 32 publications. The current research focuses on "nanoparticles", "delivery", "micells" and "doxorubicin". At present, nano based drug delivery system to improve the bioavailability of curcumin and thus to treat tumors will be the focus of future research.
    Keywords:  bibliometric analysis; curcumin; hotspots; trends; tumor
    DOI:  https://doi.org/10.3389/fonc.2022.1033683
  21. Front Psychol. 2022 ;13 914401
      Employee creativity is the foundation of organizational competitiveness, and it is also the important theme of creativity research. Based on the knowledge graph theory, this article uses the Citespace software to conduct a bibliometric analysis of 1,168 importance literature from the Web of Science and draws the co-citation and co-word clustering knowledge graph to explore research hotspots and trends of employee creativity. The research found that: First, the research on the connotation, dimensions, and behavior of employee creativity is still in the initial stage; second, the research on the psychological, behavioral, and management factors that affect employee creativity is the key content of common concern; and third, it needs to comprehensively consider relevant factors from the combination of individuals, groups, and organizations about employee creativity research. On this basis, this article proposes the main directions for future research.
    Keywords:  bibliometric analysis; co-word clustering; employee creativity; human resource management; knowledge graph co-citation relationship
    DOI:  https://doi.org/10.3389/fpsyg.2022.914401
  22. Can J Ophthalmol. 2022 Oct 25. pii: S0008-4182(22)00301-5. [Epub ahead of print]
      OBJECTIVE: To assess the impact of ophthalmology resident research and its relationship to subsequent practice.DESIGN: Cross-sectional study.
    PARTICIPANTS: Three hundred and twenty residents of Canadian ophthalmology programs graduating between 2009 and 2020.
    METHODS: Bibliometric data were obtained for each resident from Scopus. Indices of scholarly productivity included number of publications, h-index, m-quotient, and total citations. Demographic and career data were obtained from faculty listings and professional and regulatory web sites. Career outcomes included location and subspecialty of fellowship training and type of ultimate practice (academic vs community).
    RESULTS: In total, 208 of 320 graduates (65%) published at least 1 peer-reviewed article during residency. Bibliometric indices, including numbers of papers, h-index, and total citations, were significantly higher for male residents and residents who pursued academic and subspecialized practices. No significant trends were seen regarding scholarly productivity and fellowship match outcomes (e.g., location and subspecialty of fellowship). The bulk of resident research projects was of lower tiers of evidence, including retrospective studies (n = 111) and case reports (n = 108). Five-year scholarly impact of resident research decreased over time (h-index, m = -0.14; p < 0.01) despite stable publication volumes.
    CONCLUSIONS: Greater scholarly activity in residency corresponds to more academic and subspecialized practices but is not associated with type of fellowship. The impact of resident research declined between 2009 and 2020. Sex-based disparities exist.
    DOI:  https://doi.org/10.1016/j.jcjo.2022.09.005
  23. Front Pharmacol. 2022 ;13 1029020
      Background: Immunotherapy is changing the way we treat cancer. Immunogenic cell death (ICD) has received considerable attention in the treatments of various cancer types, due to the long-lasting antitumor responses elicited in human body. However, to date, no relevant bibliometric research has been reported. Methods: Publications related to ICD in cancer research were collected from the Web of Science Core Collection. Using CiteSpace, VOSviewer and an online platform, the analyses of co-author, co-citation, and co-occurrence of terms retrieved from literatures were carried out. Results: A total of 1,577 publications were included in this study. The global research literatures on ICD in cancer research have been increasing from 2005 to 2021. China, the United States and France dominated in this area and had close collaborations with many countries. Six of the top 10 most contributive institutions were from France. When it comes to author analysis, Kroemer G, Zitvogel L, Kepp O, Garg AD and Galluzzi L were in both the top 10 most productive authors and top 10 most co-cited authors lists. The co-occurring author keywords could be grouped into three clusters: "biomarkers of ICD", "nanoparticles" and "combination therapy". In terms of promising hotspots, keywords (author keywords and KeyWords Plus) with recent citation bursts could be summarized into two aspects: "tumor microenvironment" and "nanoparticles". Conclusion: Increased attention has been paid to ICD in cancer treatment. However, there are still many unresolved domains in the field of ICD, such as clinical application and molecular mechanisms of this cell death process. ICD-inducing modalities combined with nanotechnology could potentiate the current immunotherapies, and will be hotspots for future research.
    Keywords:  bibliometric analysis; cancer immunotherapy; immunogenic cell death; nanotechnology; tumor microenvironment
    DOI:  https://doi.org/10.3389/fphar.2022.1029020
  24. Toxics. 2022 Oct 19. pii: 624. [Epub ahead of print]10(10):
      Plants are susceptible to fungal pathogen infection, threatening plant growth and development. Researchers worldwide have conducted extensive studies to address this issue and have published numerous articles on the subject, but they lack a scientometric evaluation. This study analyzed international research on the topic "Plant resistance to fungal pathogens" between 2008 and 2021, using the core database of the Web of Science (WoS). By searching the subject words "Plants", "Disease Resistance", and "Fungal Pathogens", we received 6687 articles. Bibliometric visualization software analyzes the most published countries, institutions, journals, authors, the most cited articles, and the most common keywords. The results show that the number of articles in the database has increased year by year, with the United States and China occupying the core positions, accounting for 46.16% of the total published articles worldwide. The United States Department of Agriculture (USDA) is the main publishing organization. Wang Guoliang is the author with the most published articles, and the Frontiers in Plant Science ranks first in published articles. The research on plant anti-fungal pathogens is booming, and international exchanges and cooperation need to be further strengthened. This paper summarizes five possible research ideas, from fungal pathogens, gene editing technology, extraction of secondary metabolites from plants as anti-fungal agents, identification of related signal pathways, fungal molecular databases, and development of nanomaterials, to provide data for related research.
    Keywords:  Web of Science; diseases; fungal pathogens; plant resistance
    DOI:  https://doi.org/10.3390/toxics10100624
  25. J Clin Orthop Trauma. 2022 Dec;35 102018
      Background: The dissemination of research and evidence-based medicine is critical to advancing science and improving clinical practice. The purpose of this study was to evaluate the timing and associated factors of the publication process for the most influential orthopaedic surgery research journals.Methods: After analyzing 25 orthopaedic surgery journals with the highest impact factors, 14 journals provided the necessary information for data analysis. A minimum of three consecutive issues per journal from 2021 were collected for review. Within each issue, all articles were included except for reviews, commentaries, replies, letters to the editor, and invited articles. The publication times for received to accepted (RA), received to published in press (RP1), and received to published in print (RP2) were retrieved and compared. Journal impact factor, specialty, and article level of evidence were recorded.
    Results: A total of 1040 articles were included with a mean number of 74.3 ± 38 (range, 35-182) articles analyzed per journal. The mean impact factor for the 14 journals was 3.6 ± 1 (range, 2.5-5.8). The overall median duration of time for RA, RP1, and RP2 were 119 (IQR, 78-165) days, 157 (IQR, 102-216) days, and 291 (IQR, 243-378) days across all 14 journals, respectively. Journal of Arthroplasty demonstrated the shortest median duration of time for RA and RP1, while International Orthopaedics demonstrated the shortest median duration of time for RP2. Clinical Journal of Sport Medicine demonstrated the longest median duration of time for RA and RP2, while the American Journal of Sports Medicine demonstrated the longest median duration of time for RP1. Level three studies, which included retrospective case-control and cohort study designs, demonstrated the shortest publication times, while sports medicine journals demonstrated the longest publication times for all periods.
    Conclusion: There was substantial variation in publication times across orthopaedic surgery journals which may impact accessibility to clinical insights.
    Keywords:  Bibliometric analysis; Impact factor; Level of evidence; Orthopaedic surgery research journal; Publication time
    DOI:  https://doi.org/10.1016/j.jcot.2022.102018
  26. J Clin Orthop Trauma. 2022 Nov;34 102041
      Objectives: This study evaluates the publication output of the Indian authors on the topic of Arthroplasty research from 2002 to 2021, using bibliometric methods.Methods: The Indian publications as listed in the Scopus database were identified by using "Arthroplasty" or "Joint Replacement" in the keyword ("Key") tag.
    Results: India contributed 872 publications on Arthroplasty research, constituting a 1.36% share of global output, in the last two decades. Knee Arthroplasty accounted for the largest share (52.4%) in India's output, followed by Hip (35.7%) and others. 841 authors from 413 organizations participated unevenly in the research on this topic, with IISc-Bangalore contributing the largest number of publications (97), followed by Indraprastha Apollo Hospitals (46), Breach Candy Hospital, Bombay(40), and PGIMER, Chandigarh(38). R. Malhotra contributed the largest number of publications (55), followed by R. Vaishya (35 papers) and G.M. Shetty (23 papers). S. Bhan (31.0 and 3.17), A.B. Mullaji (30,13 and 3.08), N.P. Jain (25.75 and 2.63) and H.Pandit (21.88 and 2.24) registered the highest CPP & RCI. The journals which published the highest number of Arthroplasty articles were the Journal of Arthroplasty (123), followed by the Journal of Clinical Orthopaedics & Trauma (50) and International Orthopaedics (32).
    Conclusion: India's contribution in the field of Arthroplasty-related publication is still low on a global platform, however, has shown a positive and increasing trend in the last two decades. The maximum publications were related to knee and hip arthroplasty and were from institutions in the major Indian cities of Delhi and Mumbai. More international and multicentric collaboration and external funding may help improve the number of arthroplasty publications in the future.
    Keywords:  Arthroplasty; Bibliometrics; Global publications; Indian publications; Joint replacement; Scientometrics
    DOI:  https://doi.org/10.1016/j.jcot.2022.102041
  27. Naunyn Schmiedebergs Arch Pharmacol. 2022 Oct 25.
      Motivated by the 150-year anniversary of the Naunyn-Schmiedeberg's Archives of Pharmacology in 2023, we studied the bibliometric development of the journal. We evaluated data from Editorial Reports, Clarivate, and Springer Nature databases. Several parameters representing the journal's performance, such as the impact factor and social impact, were analyzed over the years. We analyzed the journal's meta-data and wrote an algorithm to retrieve cities and countries of origin. We could see a decrease in publications from Germany and an increase in papers from Brazil, China, Egypt, and Iran during the last years. The decrease in publications from Germany is probably a zeitgeist effect because this country places a strong emphasis on high-impact factor papers for academic promotion and winning grants. Germany was the country with the most publications throughout the 100 most-cited articles. Most of these articles were published between 1970 and 1990, when neurotransmitters were the most published topic. Klaus Starke (Freiburg) and Manfred Göthert (Bonn) were prominent drivers of this field. The most common topics nowadays are "Drugs for the Treatment of Malignant Tumor Diseases" and "Immunopharmacology." The internationality of the journal substantially increased after introduction of English as mandatory language in the 1970s. The journal also experienced substantial COVID-19 pandemic-related effects. This paper is not only of relevance for the field of pharmacology but for science in general in the sense that Naunyn-Schmiedeberg's Archives of Pharmacology is a case study for profound changes in a traditional scientific journal, requiring permanent adjustment by editors, referees, publisher, authors, and readers alike. The development of the journal has been strongly influenced by historic and political developments, cultural attitudes (zeitgeist), language changes, global changes in research topics, and eminent individuals who published many papers in Naunyn-Schmiedeberg's Archives of Pharmacology.
    Keywords:  Bibliometric development; COVID-19 pandemic; Historical development; Meta-data analysis; Research topics ⋅ zeitgeist
    DOI:  https://doi.org/10.1007/s00210-022-02307-2
  28. Clin Exp Pharmacol Physiol. 2022 Oct 27.
      Ferroptosis is a newly characterized form of regulated cell death. This bibliometric analysis identified the scientific output, leading institutions and research teams, current research hotspots, and trends in research on ferroptosis since the origin of the concept. We searched the Science Citation Index Expanded (SCI-expanded) of Web of Science Core Collection (WoSCC) for papers on ferroptosis up to June 03, 2022. The acquired data were analyzed and visualized by Bibliometrix package and VOSviewer. The study ultimately included 3511 relevant papers, and annual production in this field has grown rapidly in recent years. Institutions and scholars from China contributed the most work, but the impact of their research was much less than that of the United States. Prof. Brent R Stockwell's team from Columbia University in the U.S. has a very strong academic influence in the field. FRONT CELL DEV BIOL published the most papers in the field of ferroptosis. As the keywords of the papers in this field changed from the most numerous "oxidative stress", "cell-death", "iron", "expression", and "lipid-peroxidation", to "prognosis", "immunotherapy", "progression", "tumor microenvironment", and "colorectal cancer", the hotspot of ferroptosis research is gradually shifting from basic research to clinical translational research. Especially, the mechanism of tumor formation and treatment will become the frontier in the field of ferroptosis research in the future. This article is protected by copyright. All rights reserved.
    Keywords:  VOSviewer; bibliometrics; bibliometrix; cell death; ferroptosis; oxidative stress
    DOI:  https://doi.org/10.1111/1440-1681.13732
  29. J Multidiscip Healthc. 2022 ;15 2363-2374
      Objective: To examine the developmental characteristics and trends affecting clinical research nurses (CRNs) in China and provide a reference for the training and employment of nursing talents in this specialty.Methods: Literature pertaining to CRNs published from the year in which the database was constructed to 2020 was searched. The databases used were the China National Knowledge Infrastructure, Wanfang, Chinese Biomedical Literature and Weipu, while CiteSpace software was used to conduct a bibliometric analysis of literature quantity, annual distribution, literature journals and regional distribution, literature authors, subject funding status and literature type and keywords. The characteristics and trends affecting CRNs in China were then evaluated using a descriptive analysis.
    Results: A total of 3735 pieces of literature were retrieved, and after deduplication and screening, 199 pieces of literature were retained for this study. Overall, the number of publications increased year-on-year. Of these publications, 17 papers (8.5% of the retained papers) were published in the Chinese Journal of Modern Nursing and 9138 papers (69.3%) were published in the top 10 regions according to the location of the first author (of these, 31 [15.6%] were published in Beijing and 42 [21.1%] were funded by scientific research funds). The research fell mainly in the experience summary category, with 107 articles (53.8%) taking this approach. The top five research hotspots were clinical research, good clinical practice (GCP), research nurses, management and clinical trials. The practice and exploration of CRNs were regionalised, accounting for varying degrees of development. CRNs were found to be at the forefront of developments in oncology specialties.
    Conclusion: In China, CRNs are currently in a period of rapid development. Research into CRNs mainly involves single-centre studies and lacks financial support. In the future, it will be necessary to increase capital investment, strengthen cross-regional cooperation between authors and institutions to narrow the regional development gap, and promote strict and standardised CRN training models and qualification certification to improve the quality of clinical research nursing.
    Keywords:  CRNs; CiteSpace; bibliometric analysis; clinical research nurses; clinical trials; development trends
    DOI:  https://doi.org/10.2147/JMDH.S363741
  30. Healthcare (Basel). 2022 Oct 04. pii: 1942. [Epub ahead of print]10(10):
      Due to COVID-19, people's lives have changed greatly. In accordance with former experience, an efficacious vaccine is the most effective way to curb the pandemic; thus, many researchers have published related publications in the short term. Hence, this study aims at using bibliometric analysis and visualization to document research trends regarding COVID-19 vaccines, and offer some directions and suggestions for future research. Initially, all eligible publications were downloaded from Web of Science on 1 January 2022. Subsequently, some publications published before December 2019 were removed since COVID-19 did not occur before that date. Finally, Microsoft Excel is used for bibliometric analysis to analyze publication date, author, affiliation, country, publication title, publisher, research area, document type, and language, and visualized software (VOSviewer) is used to visualize author, affiliation, country, and keywords. After analyzing a total of 17,392 publications, the results show that the overall research trend was upward. Moreover, the prominent authors, institutions, and countries inclined towards regional cooperation instead of international cooperation. Furthermore, the most popular research areas were immunology and medicine (general and internal). Ultimately, COVID-19, vaccine, and SARS-CoV-2 were the top 3 keywords. In conclusion, this study shows the approximate research trend for COVID-19 vaccine during the completely first two years of the pandemic. The research focuses moved from safety, effectiveness, and immunology at the early stage to the optimal allocation strategies for COVID-19 vaccine, and eventually to public attitudes and acceptance towards COVID-19 vaccination.
    Keywords:  COVID-19; bibliometric analysis; vaccine; visualization
    DOI:  https://doi.org/10.3390/healthcare10101942
  31. Bioengineering (Basel). 2022 Oct 19. pii: 580. [Epub ahead of print]9(10):
      Over the past few decades, more and more articles about platelet-rich plasma (PRP) use in regenerative medicine have been published. The aim of this study was to determine which articles have been most influential in this field by identifying and analyzing the characteristics of the 100 most cited articles. Articles on the use of PRP in regenerative medicine were identified via the Thomson ISI Web of Science database. A majority of the articles originated from the USA (36%). The top journal in terms of number of articles was American Journal of Sports Medicine (12%). Musculoskeletal system and orthopedics (54%) were the most popular fields of applications. Preclinical studies were the most represented study type, from which only 8 from 46 (17.4%) provided a complete numerical description of the injected product. Analysis showed a time-dependent trend of increasing quality of the clinical studies (p = 0.004), although none of them provided a complete biological characterization of the injected PRP. This study demonstrated that the use of PRP in regenerative medicine is a growing and popular area of research, mainly focused on orthopedic applications. Studies on PRP-derived exosomes, biological characterization, and correlation with clinical results might be areas of future trends.
    Keywords:  bibliometric analysis; plasma rich in growth factors; platelet-rich plasma; regenerative medicine
    DOI:  https://doi.org/10.3390/bioengineering9100580
  32. Pathol Res Pract. 2022 Oct 18. pii: S0344-0338(22)00415-0. [Epub ahead of print]240 154171
      BACKGROUND: The development of whole slide image and deep neural network technologies has contributed to the paradigm shift in diagnostic pathology and has received much attention from researchers, with related publications increasing yearly and "exploding" in recent years. However, few studies have systematically reviewed "digital pathology" using bibliometric tools. In this study, we will use multiple approaches to visualize and analyze "digital pathology" to provide a comprehensive and objective picture of the field's historical evolution and future development.METHODS: We use VOSviewer, CiteSpace, Gephi, and R to analyze the authors, institutional and national collaboration networks, keyword co-occurrence, and co-citation analysis to visualize the current status of global digital pathology research.
    RESULTS: Digital pathology-related research is mainly active in "molecular, biological, and immunology" journal groups, "pharmaceutical, medical, and clinical" journal groups, and "psychology, education, and health" journal groups; in addition to "digital pathology," "diagnosis," "deep learning," "histopathology," and "surgical pathology" are also active research topics; the U.S. has significant research results in digital pathology, with the top 10 publishing institutions all coming from the U.S. In the past two decades, global digital pathology-related research can be divided into two major research areas. One is about system verification and optimization of WSI, and the other is about the application and development of artificial intelligence technology in digital pathology. Among them, based on the development of computer technology and the update of the machine learning concept, the research results for deep neural network technologies have been more concentrated in recent years. The robust performance of deep neural networks in feature extraction and image analysis provides a new research direction for improving digital pathology-aided diagnosis systems, which is where the research hotspots have been in recent years.
    CONCLUSIONS: The bibliometric analysis may help better understand the current status of research within the field of digital pathology and provide references and lessons for future related research.
    Keywords:  Data visualization and analysis; Digital pathology; Virtual microscopy; Whole slide image
    DOI:  https://doi.org/10.1016/j.prp.2022.154171
  33. Front Public Health. 2022 ;10 915037
      Cardiovascular diseases (CVD) and frailty are common health problems among the elderly. This research aims to investigate the hotspots and frontiers of the field of CVD with frailty. Data of publications between 2000 and 2021 were collected from the Web of Science Core Collection (WoSCC) and CiteSpace was used for analyzing the hotspots and frontiers of cardiovascular diseases with frailty research from high-impact countries/regions, institutions, authors, cited references, cited journals, high-frequency keywords, and burst keywords. The results showed that the USA, England, and Canada were the leading countries/regions in research on CVD with frailty. Other countries/regions and regions lagged behind these developed countries/regions. There is a need to establish cooperation between developed countries/regions and developing countries/regions. Research hotspots focused on frailty in the elderly with CVD, exercise intervention, assessment for CVD patients with frailty, quality of life, and common diseases related to CVD with frailty. The frontier fields include care and intervention of CVD patients with frailty, social frailty, and validation of CVD with frailty.
    Keywords:  bibliometric analysis; cardiovascular diseases; exercise intervention; frailty; social frailty; the elderly; visualization analysis
    DOI:  https://doi.org/10.3389/fpubh.2022.915037
  34. Front Surg. 2022 ;9 966375
      Background: Skin innervation plays an important role in wound healing by either direct contact with or indirect secretions that impact skin cells. Many studies in this field have been published; however, there is a lack of bibliometric analyses focusing on the effect of skin innervation on skin wound healing. In this study, we aimed to analyse the research trends, status, and hotspots in this field.Methods: Reviews and articles published in English were extracted from the Web of Science Core Collection (WoSCC) database based on subject term searches. Microsoft Office Excel, VOSviewer, and CiteSpace were used to analyse publication date, country or region, institution, author, and author keywords.
    Results: A total of 368 papers published between 1959 and 2022 were included in the analysis. Although there was a pulsation during this period, there was an overall upward trend in studies related to the effect of skin innervation on wound healing. The United States, particularly the University of Washington, and Gibran, Nicole S. from the University of Washington, was the most active in this field. Wound Repair and Regeneration published the most relevant literature, and "Calcitonin gene-related peptide: physiology and pathophysiology" had the highest total number of citations. "Diabetic foot ulcer," "epidermal stem cells," "mesenchymal stem cells," and "mast cells" are current and potential future research hotspots.
    Conclusion: This bibliometric analysis will inform the overall trends in research related to the effect of skin innervation on wound healing, summarise relevant research hotspots, and guide future work.
    Keywords:  Citespace; VOSviewer; WoSCC; bibliometrics; skin innervation; wound healing
    DOI:  https://doi.org/10.3389/fsurg.2022.966375
  35. Front Bioeng Biotechnol. 2022 ;10 998298
      Background: In the biotechnology and applied microbiology sectors, artificial intelligence (AI) has been extensively used in disease diagnostics, drug research and development, functional genomics, biomarker recognition, and medical imaging diagnostics. In our study, from 2000 to 2021, science publications focusing on AI in biotechnology were reviewed, and quantitative, qualitative, and modeling analyses were performed. Methods: On 6 May 2022, the Web of Science Core Collection (WoSCC) was screened for AI applications in biotechnology and applied microbiology; 3,529 studies were identified between 2000 and 2022, and analyzed. The following information was collected: publication, country or region, references, knowledgebase, institution, keywords, journal name, and research hotspots, and examined using VOSviewer and CiteSpace V bibliometric platforms. Results: We showed that 128 countries published articles related to AI in biotechnology and applied microbiology; the United States had the most publications. In addition, 584 global institutions contributed to publications, with the Chinese Academy of Science publishing the most. Reference clusters from studies were categorized into ten headings: deep learning, prediction, support vector machines (SVM), object detection, feature representation, synthetic biology, amyloid, human microRNA precursors, systems biology, and single cell RNA-Sequencing. Research frontier keywords were represented by microRNA (2012-2020) and protein-protein interactions (PPIs) (2012-2020). Conclusion: We systematically, objectively, and comprehensively analyzed AI-related biotechnology and applied microbiology literature, and additionally, identified current hot spots and future trends in this area. Our review provides researchers with a comprehensive overview of the dynamic evolution of AI in biotechnology and applied microbiology and identifies future key research areas.
    Keywords:  applied microbiology; artificial intelligence; bibliometric; biotechnology; deep learning; machine learning
    DOI:  https://doi.org/10.3389/fbioe.2022.998298
  36. Front Immunol. 2022 ;13 967076
      Background: Immunotherapy has shown great potential for the treatment of multiple cancer and has been proven to be closely related to the tumor microenvironment. This article reveals collaborations and interactions among authors, nations, organizations, and periodicals assesses the knowledge base, and discovers hot tendencies and new topics associated with immunotherapy-tumor microenvironment (TME) research.Methods: This article utilized bibliometrics and visual methods to provide a comprehensive overview of immunotherapy-TME research. Our team retrieved the WoSCC for research and reviews associated with immunotherapy and the tumor microenvironment. VOSviewer and Citespace were primarily used for literature measurement and knowledge graph analysis.
    Result: All English articles and reviews on cancer immunotherapy effectiveness were collected, and 1,419 academic journals with 53,773 authors from 7,008 institutions in 92 countries/regions were found. Publications associated with immunotherapy-TME research were stably increasing. Frontiers of Immunology (n = 722) published the most papers on immunotherapy-TME, and Cancer Research (n = 6761) was the top co-cited journal. The published journals and co-cited journals focused on cancer and immunology fields. The League of European Research Universities (n = 978), Harvard University (n = 528), and the University of Texas system (n = 520) were the most productive institutions. Yang Liu (n = 34) and Topalian (n = 1978) ranked first among the top 10 scholars and co-cited scholars. Simultaneously, immunotherapy-TME researchers were involved in active collaborations. Elements of TME, the foundation of immunotherapy, and the application of immunotherapy in cancers represented the three principal aspects of immunotherapy-TME research. The latest hot spots are drug resistance, prognosis prediction, efficacy prediction, and m6A. Nanomedicine and m6A may be future hot topics. Future research in immunotherapy-TME may be directed at discovering how m6A modification affects tumor development by altering the tumor microenvironment and exploring how to enhance response or reduce drug resistance to immunotherapy by reversing or mediating the physicochemical properties of the TME.
    Conclusions: M6A and nanomedicine are also emerging hotspots in time zone diagrams with high centrality, and prognosis prediction using bioinformatics based on the development of prediction technology may be another future research hotspot.
    Keywords:  bibliometric; cancer; immunotherapy; prognosis; tumor microenvironment
    DOI:  https://doi.org/10.3389/fimmu.2022.967076
  37. Heliyon. 2022 Oct 17. e11120
      Objective: To perform a bibliometric analysis of published research related to the use of traditional Chinese medicine (TCM) for the treatment of Coronavirus Disease 2019 (COVID-19).Methods: Research documents related to the use of TCM for prevention and treatment of COVID-19 published up to September 19, 2021, were retrieved from the Web of Science database. Bibliometrix R 4.0 software package was used to analyze data, including countries of publication, research institutions, journals, citations, and keywords. Further analysis was conducted to identify co-occurrence of keywords in the documents, including their titles and abstracts. Cooperative network analyses of authors, institutions, and countries of publication were also conducted. The classification types were statistically analyzed and the research progress of key TCMs was reviewed.
    Results: A total of 417 documents were included in our analysis. Of these, 85.13% originated in China. Of the 417 documents, 148 (35.5%) were published in journals with impact factors in quartile 1 and 164 (39.3%) in journals in quartile 2. The documents were mainly published in journals categorized as Medicine. The results of network analysis showed close cooperation between institutions and countries. Excluding disease- and drug-related keywords, the top four keywords were 'Systematic review', 'Network pharmacology', 'Medicine' and 'Molecular docking'. Keyword co-occurrence analysis showed 4 main keywords association groups. Statistical analysis of the TCM studies showed that Lianhua Qingwen capsule, Qingfei Paidu decoction, Shufeng Jiedu capsules and ReDuNing injection were the most studied Chinese medicines. Lianhua Qingwen capsules, Qingfei Paidu decoction, ReDuNing injection, and Shufeng Jiedu capsules were used in clinical, bioinformatics, and basic research. Toujie Quwen granule, Jinhua Qinggan granule, Shuanghuanglian oral liquid, Tanreqing injection, and Xuanfei Baidu decoction were used in clinical and bioinformatics research, although basic research on their mechanisms of action is lacking.
    Conclusion: Research intensity and recognition, as well as cooperation, in the field of Chinese medicine for the prevention and treatment of COVID-19 has increased. Research types are generally comprehensive, and investigated several TCM formulations that are specifically recommended by Chinese COVID-19 guidelines. However, comprehensive, in-depth research on their molecular mechanisms of action is still lacking. More basic research is thus needed to identify therapeutic mechanisms to standardize and validate the use of TCM in the prevention and treatment of COVID-19.
    Keywords:  Bibliometrics; COVID-19; Coronavirus disease 2019; Prevention; Traditional Chinese medicine; Treatment
    DOI:  https://doi.org/10.1016/j.heliyon.2022.e11120
  38. Environ Sci Pollut Res Int. 2022 Oct 24.
      To assess the status of hotspots and research trends on geographic information system (GIS)-based landslide susceptibility (LS), we analysed 1142 articles from the Thomas Reuters Web of Science Core Collection database published during 2001-2020 by combining bibliometric and content analysis. The paper number, authors, institutions, corporations, publication sources, citations, and keywords are noted as sub/categories for the bibliometric analysis. Thematic LS data, including the study site, landslide inventory, conditioning factors, mapping unit, susceptibility models, and mode fit/prediction performance evaluation, are presented in the content analysis. Then, we reveal the advantages and limitations of the common approaches used in thematic LS data and summarise the development trends. The results indicate that the distribution of articles shows clear clusters of authors, institutions, and countries with high academic activity. The application of remote sensing technology for interpreting landslides provides a more convenient and efficient landslide inventory. In the landslide inventory, most of the sample strategies representing the landslides are point and polygon, and the most frequently used sample subdividing strategy is random sampling. The scale effects, lack of geographic consistency, and no standard are key problems in landslide conditioning factors. Feature selection is used to choose the factors that can improve the model's accuracy. With advances in computing technology and artificial intelligence, LS models are changing from simple qualitative and statistical models to complex machine learning and hybrid models. Finally, five future research opportunities are revealed. This study will help investigators clarify the status of LS research and provide guidance for future research.
    Keywords:  Bibliometric analysis; Content analysis; GIS; Landslide susceptibility; Machine learning; Research trends
    DOI:  https://doi.org/10.1007/s11356-022-23732-z
  39. Indian Dermatol Online J. 2022 Sep-Oct;13(5):13(5): 578-584
      Scientometric indices help rank the impact of an article, an author, and a journal in scientific literature. Additionally, it helps to rank institutions, universities, and countries in the scientific field. There are various author-, article-, and journal-level metrics provided by different service providers. It is important to know the underlying calculation method for an informed comparison between authors, articles, and journals. In this article, we described briefly some of the common author-level metrics (h-index, i10-index, and g-index), article-level metrics (Altmetric, Dimensions, and PlumX), and journal-level metrics (Impact Factor®, CiteScore, SCImago journal ranking, and h5-index).
    Keywords:  Altmetric; CiteScore; Dimensions; PlumX; SCImago; g-index; h-index; h5-index; i10-index; impact factor
    DOI:  https://doi.org/10.4103/idoj.idoj_729_21
  40. Biomolecules. 2022 Oct 12. pii: 1464. [Epub ahead of print]12(10):
      Brain-derived neurotrophic factor (BDNF), as the most widely distributed and widely studied neurotrophic factor in the mammalian brain, plays a key role in depression and the mechanisms of action for antidepressants. Currently, there is a large number of studies on the role of BDNF in the pathogenesis and therapeutic mechanism of depression. The quantity and quality of these studies, however, are unknown. To give beginners a quicker introduction to this research topic, we therefore performed a bibliometric analysis. A total of 5300 publications were included. We obtained the publications on this topic from the Web of Science database, and a variety of bibliographic elements were collected, including annual publications, authors, countries/regions, institutions, journals, and keywords. Moreover, we found that oxidative stress and neuroinflammation are the hotspots in the field in very recent years. Collectively, this study provides a comprehensive summary and analysis on the role of BDNF in depression and its treatment and offers meaningful values for beginners on this topic.
    Keywords:  bibliometric analysis; brain-derived neurotrophic factor; depression; research trends; treatment
    DOI:  https://doi.org/10.3390/biom12101464
  41. Front Reprod Health. 2022 ;4 757143
      Background: Intrauterine adhesionis caused by a variety of reasons, such as damage of the endometrial basal layer, adhesion or occlusion of the uterine cavity or cervix in different degrees. Seriously endangering women's physical and mental health.Objective: The purpose of this paper is to analyze the research development of intrauterine adhesions in recent 15 years, explore the future development direction, and promote the development of this field.
    Methods: With intrauterine adhesions and Ashman's syndrome as the theme, the related literatures from January 2006 to July 2021 in the Web of Science were searched, and the visual atlas was analyzed by CiteSpace software.
    Results: A total of 644 literatures were included. The key words related to intrauterine adhesion mainly include adhesion, pregnancy, expression, intrauterine adhesions, women, adhesion molecule, diagnosis, activation, hysteroscopy and fertility, etc. Six clusters were obtained by keywords analysis, involving hysteroscopy, placenta, office hysteroscopy, uterus and laparoscopy. Co-occurrence of keywords shows that the research focus in recent years is on endometrial repair and regeneration.
    Conclusions: Through the bibliometric analysis of WOS research on intrauterine adhesions in recent 15 years, the comprehensive analysis of countries, institutions, authors and keywords is obtained, which has a clear guiding significance for guiding the future development of intrauterine adhesions.
    Keywords:  Ashman's syndrome; CiteSpace; intrauterine adhesionis; knowledge mapping; visualization analysis
    DOI:  https://doi.org/10.3389/frph.2022.757143
  42. Int J Environ Res Public Health. 2022 Oct 14. pii: 13273. [Epub ahead of print]19(20):
      With increasing environmental regulation (ER), the requirements for green technology innovation (GTI) in enterprises are also rising. However, there are relatively few systematic summaries of the themes of ER-affecting GTI. Adopting the method of bibliometrics and visual analysis, this research discusses the status of research and development trends of ER-affecting GTI and summarizes the research in this field. The paper takes 738 papers from 2001 to 2021 in the core database of Web of Science as the research sample. Based on CiteSpace, this paper makes a visual analysis of the number of published papers, institutions, authors, keywords, countries (regions) and journals. The study found that to some extent, favorable collaboration between authors and institutions in this field needs to be strengthened. Research hotspots in this field include innovation, technology, performance, policy and environmental regulation. Renewable energy consumption, the pollution haven hypothesis, sustainable development, carbon dioxide emission, energy technology and environmental Kuznets curve are the current research frontiers in this field. In terms of the number of published papers, research in this field has been conducted in a national (regional) layout with China as the core force, and Italy, America, Britain, Germany and other European countries as important forces. This field covers three main research areas: enterprise performance, policy instruments and research methods, going through the start-up phase (2001-2011), the growth phase (2012-2018) and the development phase (2019-2021). Future research can further incorporate the digital economy and synergy of multiple environmental regulation policies into this field, which will continuously enrich the theoretical research system in this field. The content, methods and conclusions of research in this field are becoming increasingly diverse.
    Keywords:  CiteSpace; bibliometrics; environmental regulation; green technology innovation
    DOI:  https://doi.org/10.3390/ijerph192013273
  43. Med Educ. 2022 Oct 25.
      INTRODUCTION: The voices of authors who publish medical education literature have a powerful impact on the field's discourses. Researchers have identified a lack of author diversity, which suggests potential epistemic injustice. This study investigates author characteristics to provide an evidence-based starting point for communal discussion with the intent to move medical education towards a future that holds space for, and values, diverse ways of knowing.METHOD: The authors conducted a bibliometric analysis of all articles published in 24 medical education journals published between 2000-2020 to identify author characteristics, with an emphasis on author gender and geographic location and their intersection. Article metadata was downloaded from Web of Science. Genderize.io was used to predict author gender.
    RESULTS: The journals published 37,263 articles authored by 62,708 unique authors. Males were more prevalent across all authorship positions (n=62,828; 55.7%) than females (n=49,975; 44.3%). Authors listed affiliations in 146 countries of which 95 were classified as Global South. Few articles were written by multinational teams (n=3,765; 16.2%). Global South authors accounted for 12,007 (11.4%) author positions of which 3,594 (3.8%) were female.
    DISCUSSION: This study provides an evidence-based starting point to discuss the imbalance of author voices in medical education, especially when considering the intersection of gender and geographical location, which further suggests epistemic injustice in medical education. If the field values a diversity of perspectives, there is considerable opportunity for improvement by engaging the community in discussions about what knowledge matters in medical education, the role of journals in promoting diversity, how to best use this baseline data, and how to continue studying epistemic injustice in medical education.
    DOI:  https://doi.org/10.1111/medu.14959
  44. Sensors (Basel). 2022 Oct 14. pii: 7814. [Epub ahead of print]22(20):
      Geohazard prevention and mitigation are highly complex and remain challenges for researchers and practitioners. Artificial intelligence (AI) has become an effective tool for addressing these challenges. Therefore, for decades, an increasing number of researchers have begun to conduct AI research in the field of geohazards leading to rapid growth in the number of related papers. This has made it difficult for researchers and practitioners to grasp information on cutting-edge developments in the field, thus necessitating a comprehensive review and analysis of the current state of development in the field. In this study, a comprehensive scientometric analysis appraising the state-of-the-art research for geohazard was performed based on 9226 scientometric records from the Web of Science core collection database. Multiple types of scientometric techniques, including coauthor analysis, co-citation analysis, and cluster analysis were employed to identify the most productive researchers, institutions, and hot research topics. The results show that research related to the application of AI in the field of geohazards experienced a period of rapid growth after 2000, with major developments in the field occurring in China, the United States, and Italy. The hot research topics in this field are ground motion, deep learning (DL), and landslides. The commonly used AI algorithms include DL, support vector machine (SVM), and decision tree (DT). The obtained visualization on research networks offers valuable insights and an in-depth understanding of the key researchers, institutions, fundamental articles, and salient topics through animated maps. We believe that this scientometric review offers useful reference points for early-stage researchers and provides valuable in-depth information to experienced researchers and practitioners in the field of geohazard research. This scientometric analysis and visualization are promising for reflecting the global picture of AI-based geohazard research comprehensively and possess potential for the visualization of the emerging trends in other research fields.
    Keywords:  artificial intelligence (AI); geohazard; research cluster; scientometric; visualization
    DOI:  https://doi.org/10.3390/s22207814
  45. J Pers Med. 2022 Sep 24. pii: 1574. [Epub ahead of print]12(10):
      BACKGROUND: Compassion fatigue is a common phenomenon among healthcare professionals and includes several concepts that share a direct relationship with quality of life, with consequences on both physical and emotional well-being but also at the economic and organizational levels.OBJECTIVES: To analyze the profile of scientific publications on compassion fatigue, dissecting trends, and highlighting research opportunities.
    METHOD: Bibliometric analysis based on Donthu's guidelines, data collection from Web of Science (Clarivate Analytics), and analytic techniques (performance analysis and science mapping) with VOSviewer® and CiteSpace®.
    RESULTS: We obtained 1364 articles and found that the concept emerged in 1995 and is frequently associated with areas of general health. Through analysis, we identified the following research frontiers: "vicarious traumatization", "working", "survivor", "mental health", and "impact".
    CONCLUSION: There has been a growing interest in this subject among researchers, with an increase in scientific production related to areas of health such as nursing, providing a solid starting point for further investigation. Registration number from the Open Science Framework: osf.io/b3du8.
    Keywords:  bibliometrics; compassion; compassion fatigue
    DOI:  https://doi.org/10.3390/jpm12101574
  46. Disabil Rehabil Assist Technol. 2022 Oct 28. 1-9
      PURPOSE: This study uses a bibliometric approach to analyse the patterns in research related to mobile and wearable technologies for persons with disabilities to evaluate the current state of relevant research.MATERIALS AND METHODS: A systematic search was done using two strings covering "disability" and "mobile and wearable technologies" in the titles of publications in the Web of Science database. Two researchers independently screened the results for relevant publications. During this process, the inclusion and exclusion criteria were deliberated and refined. An independent researcher checked the screening results against the finalized inclusion and exclusion criteria to ensure that the screening was done consistently.
    RESULTS: A total of 2012 out of the 5990 retrieved publications from 2000 to 2022 were included for further analysis. We observed that publications in this area grew exponentially since 2011, almost doubling every 2 years between 2011 and 2015. Universities in the USA were the most active and prominent in relevant publications. Autism is the most researched disability in relation to mobile and wearable technologies. The publications cover both hardware (engineering, electrical and electronic) and software (computer science, theory and methods) technologies used for improving quality of life for persons with disabilities (rehabilitation).
    CONCLUSIONS: The majority of publications were from high income countries, indicating the need to study the digital divide among high-, low- and middle-income countries in adopting mobile and wearable technologies for persons with disabilities, especially ways of making these technologies more affordable and accessible to the under-privileged members of the community.
    Keywords:  Mobile technologies; bibliometric; disabilities; wearable technologies
    DOI:  https://doi.org/10.1080/17483107.2022.2138996
  47. Ann Plast Surg. 2022 Nov 01. 89(5): 478-486
      BACKGROUND: As more plastic surgery clinicians pursue advanced degrees and strive to become stronger physician-scientists, an objective understanding of how such degrees influence careers becomes important. We hypothesized that having a master's degree is associated with higher scholarly activity, research funding, academic progression, and leadership appointments.METHODS: Accreditation Council for Graduate Medical Education-accredited integrated plastic surgery residency program Web sites were queried to create a data set of current academic plastic surgeons (APSs) and plastic surgery residents (PSRs). Scholarly metrics such as publications, citations, and H-indices were extracted from the Scopus database. National Institutes of Health and Plastic Surgery Foundation funding information was collected through their respective Web sites.
    RESULTS: Our cohort comprised 799 APSs and 922 PSRs, of whom 8% and 7.4%, respectively, had at least one master's degree. Academic plastic surgeons with master's of public health degrees had a significantly higher median number of publications and citations than APSs without a master's of public health. There was no association between any master's degree and academic rank or being a department chairman or program director. Academic plastic surgeons with master of science degrees were more likely to receive National Institutes of Health grants. Among PSRs, master's of science graduates had a higher median number of publications. Other master's degrees did not significantly influence scholarly productivity or funding.
    CONCLUSIONS: Certain master's degrees had an impact on scholarly productivity, with no significant effect on academic rank or leadership positions. The value of master's degrees in programs focusing on healthcare management, leadership skills, and business acumen likely extends beyond the scope of this study.
    DOI:  https://doi.org/10.1097/SAP.0000000000003295
  48. Front Bioeng Biotechnol. 2022 ;10 921092
      Bone regeneration materials (BRMs) bring us new sights into the clinical management bone defects. With advances in BRMs technologies, new strategies are emerging to promote bone regeneration. The aim of this study was to comprehensively assess the existing research and recent progress on BRMs, thus providing useful insights into contemporary research, as well as to explore potential future directions within the scope of bone regeneration therapy. A comprehensive literature review using formal data mining procedures was performed to explore the global trends of selected areas of research for the past 20 years. The study applied bibliometric methods and knowledge visualization techniques to identify and investigate publications based on the publication year (between 2002 and 2021), document type, language, country, institution, author, journal, keywords, and citation number. The most productive countries were China, United States, and Italy. The most prolific journal in the BRM field was Acta Biomaterialia, closely followed by Biomaterials. Moreover, recent investigations have been focused on extracellular matrices (ECMs) (370 publications), hydrogel materials (286 publications), and drug delivery systems (220 publications). Research hotspots related to BRMs and extracellular matrices from 2002 to 2011 were growth factor, bone morphogenetic protein (BMP)-2, and mesenchymal stem cell (MSC), whereas after 2012 were composite scaffolds. Between 2002 and 2011, studies related to BRMs and hydrogels were focused on BMP-2, in vivo, and in vitro investigations, whereas it turned to the exploration of MSCs, mechanical properties, and osteogenic differentiation after 2012. Research hotspots related to BRM and drug delivery were fibroblast growth factor, mesoporous materials, and controlled release during 2002-2011, and electrospinning, antibacterial activity, and in vitro bioactivity after 2012. Overall, composite scaffolds, 3D printing technology, and antibacterial activity were found to have an important intersection within BRM investigations, representing relevant research fields for the future. Taken together, this extensive analysis highlights the existing literature and findings that advance scientific insights into bone tissue engineering and its subsequent applications.
    Keywords:  bibliometric analysis; bone regeneration material; drug delivery; extracellular matrix; hydrogel
    DOI:  https://doi.org/10.3389/fbioe.2022.921092
  49. High Educ (Dordr). 2022 Oct 19. 1-24
      The journal, Higher Education (HE), was established in 1972 and is currently one of the leading international journals in higher education studies. By using bibliometric techniques, a systematic review, and a social network analysis, this review article provides an overview of the main patterns of publications in HE during its history. The findings show that (i) the volume of articles has been continuously increasing, with a particular marked uplift since 2007; (ii) while single-authored articles have dominated the publication pattern, collaborative articles have shown a particular growth over the last decade; (iii) the USA, the UK, and Australia have dominated the journal in terms of the number of articles, international collaboration, and the most prolific authors; (iv) while Chinese authors have become more evident, there has been a near-absence of contributions from Latin America, Eastern Europe, and most of Africa; (v) in the entire history of HE, there has been a gender imbalance (in favour of male authors) across the most cited articles, but this pattern has changed in the last decade and; (vi) both teaching and learning and system policy have been key research themes in the journal although internationalisation and the student experience have recently gained traction. These patterns of publication in HE, with their imbalances and absences, suggest several challenges ahead.Supplementary Information: The online version contains supplementary material available at 10.1007/s10734-022-00924-7.
    Keywords:  Bibliometrics; Higher Education; Review article; Social network analysis; Systematic review
    DOI:  https://doi.org/10.1007/s10734-022-00924-7
  50. Front Psychol. 2022 ;13 865629
      Based on 454 articles related to college students' entrepreneurial intention in the Web of Science Core Collection, this study explores the hotspots and trends of international research on college students' entrepreneurial intention by using a combination of coding and bibliometric analysis. The research hotspots are as follows: the theory of planned behavior is the main theoretical basis of these studies; entrepreneurship education is a more important predictor of college students' entrepreneurial intention, and this relationship is regulated by multiple variables; personal traits, several types of capital theories, social entrepreneurial intention, and quantitative research methods are also common. The research fronts include the following: systematic review of the field, continuous attention to the theory of planned behavior, and in-depth exploration of the differentiated influence of entrepreneurship education on entrepreneurial intention. Finally, we proposed research thinking and prospects related to research on undergraduates' entrepreneurial intention and entrepreneurship education.
    Keywords:  college students; entrepreneurial intention; entrepreneurship education; research fronts; research hotspots
    DOI:  https://doi.org/10.3389/fpsyg.2022.865629
  51. Am J Emerg Med. 2022 Oct 19. pii: S0735-6757(22)00663-5. [Epub ahead of print]63 22-28
      OBJECTIVES: To describe first author gender differences and characteristics in 1) Society for Academic Emergency Medicine (SAEM) Annual Meeting abstracts and 2) resulting manuscript publications.METHODS: We performed cross-sectional evaluation of SAEM abstracts from 1990, 1995, 2000, 2005, 2010, 2015, and 2020, compiling and reviewing a random sample of 100 abstracts for each year (total n = 700 abstracts). We documented abstract characteristics, including first author gender, and used the 2020 SAEM scoring rubric. We then searched PubMed to identify manuscript publications resulting from abstracts from 1990 to 2015 (n = 600). Finally, among abstracts that resulted in manuscript publication, we identified first and last author gender on both the abstracts and the resulting publication.
    RESULTS: Overall, 29% (202/695; n = 5 missing gender) of abstracts had female first authors. Female first authors increased over time (e.g., 17% in 1990 to 35% in 2020). Abstract quality scores were similar (both median [interquartile range] of 11 ([9-12]). Overall, 42% (n = 254/600) of abstracts resulted in a manuscript publication, 39% (n = 65/202) with female and 44% (n = 189/493) with male first authors (p = 0.26). The median time (IQR) from abstract to manuscript publication was longer for abstracts with female first authors vs. those with male first authors (2 [1-3] years and 1 [1, 2] years, p < 0.02); 77% and 78% of publications resulting from abstracts with female and male first authors, respectively, had the same first author. Female first author abstracts more often converted to a male first author manuscript publication (18%, n = 12/65) compared to male first author abstracts converting to female first author publications (7%, n = 14/189).
    CONCLUSIONS: A minority of SAEM abstracts, and manuscript publications resulting from them, had female first authors. Abstracts with female first authors took longer to achieve manuscript publication, and almost a fifth of female first author abstracts resulted in male first author manuscript publication.
    Keywords:  Authorship; Emergency medicine; Gender disparity
    DOI:  https://doi.org/10.1016/j.ajem.2022.10.028
  52. J Dent Sci. 2022 Oct;17(4): 1854-1858
      Scientometric analysis of a disease is often conducted to recognize research trends and study hotspots. In this report, we analyze the scientometric characteristics of oral potentially malignant disorder (OPMD) research in Taiwan and mainland China. There are 324 and 718 articles on OPMD research originating from Taiwan and Mainland between 2006 and 2021, respectively. The most common subtype of OPMD research in Taiwan and Mainland is oral submucous fibrosis and lichen planus, respectively. Based on the list of main keywords extracted from the included articles, areca/betel quid chewing and alcohol use are the distinctive risk factors in Taiwan. Research on cancer screening, fibroblast/myofibroblast, and smooth muscle actin α are distinctive keywords in Taiwan; whereas the research on apoptosis, cytokine, and inflammation are distinctive keywords in Mainland. The distinctive characteristics of OPMD research are analyzed between Taiwan and mainland China, which may reflect the importance and concerned topics of research.
    Keywords:  Bibliometric; Citation analysis; Oral potentially malignant disorder; Oral squamous cell carcinoma; Risk factors
    DOI:  https://doi.org/10.1016/j.jds.2022.06.003
  53. J Educ Perioper Med. 2022 Jul-Sep;24(3):24(3): E689
      Clinical production pressure is a significant problem for faculty of anesthesiology departments who seek to remain involved in research. Lack of protected time to dedicate to research and insufficient external funding add to this long-standing issue. Recent trends in funding to the departments of anesthesiology and their academic output validate these concerns. A 2022 study examining National Institutes of Health (NIH) grant recipients associated with anesthesiology departments across 10 years (2011-2020) outlines total awarded funds at $1,676,482,440, with most of the funds awarded to only 10 departments in the United States. Of note, the total 1-year NIH funding in 2021 for academic internal medicine departments was 3 times higher than the 10-year funding of anesthesiology departments. Additionally, American Board of Anesthesiology (ABA) diplomats represent a minority (37%) of the anesthesiology researchers obtaining grant funding, with a small number of faculty members receiving a prevalence of monies. Overall, the number of publications per academic anesthesiologist across the United States remains modest as does the impact of the scholarly work. Improving environments in which academic anesthesiologists thrive may be paramount to successful academic productivity. In fact, adding to the lack of academic time is the limited bandwidth of senior academic physicians to mentor and support aspiring physician scientists. Given then the challenges for individual departments and notable successes of specialty-specific collaborative efforts (eg Foundation for Anesthesia Education and Research [FAER]), additional pooled-resource approaches may be necessary to successfully support and develop clinician scientists. It is in this spirit that the leadership of Anesthesia and Analgesia and the Journal of Education in Perioperative Medicine, unified with the Association of University Anesthesiologists, aim to sponsor the Introduction to Clinical Research for Academic Anesthesiologists (ICRAA) Course. Directed toward early career academic anesthesiologists who wish to gain competency specifically in the fundamentals of clinical research and receive mentorship to develop an investigative project, the yearlong course will provide participants with the skills necessary to design research initiatives, ethically direct research teams, successfully communicate ideas with data analysts, and write and submit scientific articles. Additionally, the course, articulated in a series of interactive lectures, mentored activities, and workshops, will teach participants to review articles submitted for publication to medical journals and to critically appraise evidence in published research. It is our hope that this initiative will be of interest to junior faculty of academic anesthesiology departments nationally and internationally.
    DOI:  https://doi.org/10.46374/volxxiv_issue3_cavallone
  54. Psychiatr Genet. 2022 Oct 21.
      INTRODUCTION: The distribution pattern and knowledge structure of psychiatric genomics were surveyed based on literature dealing with both psychiatry and genomics/genetics. Coword analysis and bibliographic coupling of the records retrieved from Scopus and PubMed for 2016-2020 revealed the subsurface research aspects.METHOD: The data were analyzed using coword analysis and clustering methods using Sci2 and VOSviewer.
    RESULT: Analysis of ~3800 records showed that psychiatric genomics is, as expectedly, covered largely under biomedical subjects with a visible interest in other disciplines such as humanities and ethics. A coword analysis was done for all the years, followed by a year-wise analysis based on the keywords, and then a bibliographic coupling based on the cited references. This led to the generation of different clusters of prevalent research areas. The centrality values described the position of each component.
    DISCUSSION: 'Schizophrenia', 'depression', 'pharmacogenomics', and 'immunopathogenesis' were the research topics of overarching interest. 'Gut-brain axis' and 'gene-environment interaction' were the emerging topics, whereas certain topics such as 'child and adolescent psychiatry' remained priorities when compared to earlier studies. The keywords and research focus were diverse. They ranged from genetics to transcriptomics and epigenetics to proteomics of psychiatric disorders. We found a stagnation of science communication in the field with only 0.2% of the articles from the entire corpus relevant to it. The research categories identified in this study reflect the current publication and research trends in psychiatric genomics.
    DOI:  https://doi.org/10.1097/YPG.0000000000000325
  55. Healthcare (Basel). 2022 Oct 11. pii: 2000. [Epub ahead of print]10(10):
      The purpose of this study was to determine the 50 most cited articles on shoulder arthroplasty (SA) and their characteristics. The Thomson ISIWeb of Science was searched with the following search terms: "shoulder arthroplasty", "shoulder replacement", "shoulder prosthesis" and "shoulder implant". All papers dealing with SA, including its perioperative and postoperative management, were included in this study. Citations ranged from 797 to 52 for the 50 highest cited papers on SA. According to absolute numbers, the top 10 papers were cited at least 118 times. Overall, 78% (n = 43) were clinical and the remaining articles were basic science research (one anatomic, six biomechanical). The most prevalent level of evidence was IV (72%). The Journal of Shoulder and Elbow Surgery published 40% of the studies. The majority of studies were conducted in the United States and eight other countries. The publication years of the most-cited articles ranged from 1991 to 2020, with the 2000s accounting for the most articles (96%) and the period from 2006 to 2010 with the absolute largest number of articles (17). This article provides a building block in the SA surgery.
    Keywords:  glenohumeral arthritis; humerus fracture; reverse total shoulder arthroplasty; rotator cuff; shoulder arthroplasty; shoulder biomechanics
    DOI:  https://doi.org/10.3390/healthcare10102000
  56. Heliyon. 2022 Oct;8(10): e11047
      This work is mainly aimed at the detection, visualization and description of the scientific collaboration patterns in the Nursing field in Latin America as a response to the lack of evidence on the implications of collaboration and its effects on the scientific influence in the Nursing field. For this purpose, a retrospective quantitative analysis was conducted by including all the publications classified under the code 2900 in All Science Journal Classification Codes of Scopus, corresponding to the field of General Nursing during 2005-2020. A total of 40 countries and 362,354 unique publications were analyzed, although the main subset herein consists of 18,371 unique publications authored by Latin-American institutions. World proportion of Latin-American publications in Nursing is higher than all the publications in the region. This increase is especially remarkable in the latest year of the studied period, which may result from the progressive increase in the numbers of nursing schools, the diversity in the graduate and specialization programs, the creation of scientific societies, and the many conferences carried out recently on Nursing.
    Keywords:  Citation analysis; Collaboration networks; International cooperation; Latin America; Network analysis; Nurse specialists; Quantitative evaluation; Scientific collaboration
    DOI:  https://doi.org/10.1016/j.heliyon.2022.e11047
  57. World J Gastroenterol. 2022 Oct 14. 28(38): 5648-5657
      BACKGROUND: Accurate assessment of the quality of academic journals is of great significance. While Journal Impact Factor (JIF), calculated by Clarivate and based upon the Web of Science literature database, and CiteScore (CS), developed by Elseiver and based upon the Scopus database, have enjoyed high uptake worldwide, efforts continue towards creation of other scientometric indexes that will provide ever-greater qualitative insights into journal impact. Such efforts have yielded the newly-launched Journal Article Influence Index (JAII), which is based on the Reference Citation Analysis (RCA) database, an open multidisciplinary citation analysis database based on artificial intelligence technology.AIM: To evaluate and summarize the similarities and differences between JAII and JIF/CS as journal evaluation indicators, and provide an intuitive method for visual representation of the related data.
    METHODS: We searched the Journal Citation Reports to obtain the 2021 JIF list, downloaded the CS list updated in July on the Scopus website, and collected the comprehensive list of 2022 JAIIs from the RCA database (www.referencecitationanalysis.com).
    RESULTS: Our research results revealed that by breaking through the time limit of mainstream journal evaluation methods, the JAII is able to perform well in data reliability, establishing its benefit as a complementary scientometric index to JIF and CS.
    CONCLUSION: JAII provides comprehensive assessment of the quality and performance of journals.
    Keywords:  CiteScore; Gastroenterology and Hepatology; Journal Article Influence Index; Journal Impact Factor; Scientometric index
    DOI:  https://doi.org/10.3748/wjg.v28.i38.5648
  58. BMJ Open. 2022 Oct 26. 12(10): e064954
      OBJECTIVES: Female physicians in medicine are increasing, but disparities in female authorship exist. The aim of this study was to characterise factors associated with female first (FF) and female senior (SF) authorship in later phase systemic oncological clinical trials in biliary tract cancer (BTC) and identify any changes over time.SETTING: Embase/Medline identified trial publications in BTC (2000-2020) were included. χ2 tests and log regression were used (assessed factors associated with FF and SF authorship, including changes over time (STATA V.16)).
    PRIMARY OUTCOME MEASURE: FF and SF authorship in later phase systemic oncological clinical trials in BTC.
    SECONDARY OUTCOME MEASURE: Any changes over time?
    RESULTS: Of 501 publications, 163 met inclusion criteria. The median percentage of female author representation in publications was 25%; there were no female authors in 13% of publications. Geographic location of the home institution of the first and senior authors was Asia (42%/42%), Europe (29%/29%), USA (24%/22%) and other (4%/6%), respectively. Overall, FF and SF author representation was 20% and 10%, respectively. The median position of the first female author was second in all the publication author lists. The phase of trial, journal-impact factor, industry funding or whether the study met its primary endpoint did not impact FF/SF author representation. More SF authors had home institutions in 'other' geographic locations (40% in 10 trials) (p=0.02) versus Asia (6%), Europe (8%) and USA (14%). There were no significant changes in FF/SF representation over time (p=0.61 and p=0.33 respectively).
    CONCLUSIONS: FF and SF author representation in later phase systemic clinical trial publications in BTC is low and has not changed significantly over time. The underlying reasons for this imbalance need to be better understood and addressed.
    Keywords:  adult oncology; chemotherapy; hepatobiliary tumours
    DOI:  https://doi.org/10.1136/bmjopen-2022-064954
  59. Pharm Nanotechnol. 2022 Oct 19.
      OBJECTIVE: To produce a geo-referenced map of the status of R&D in COVID-related studies in the World Methodology: Spatial mapping of bibliometric data of Cortellis Drug Discovery Intelligence through an spatial bibliometric model with the aid of a GIS (Geographic Information System) called ArcGIS and the software.RESULTS: We show the countries that have most studies related to COV ID-19 and their degree of collaboration. No drug discovery-related activity was found in South America and Africa. A geo-referenced map of the most active countries in COVID research was constructed as well as conceptual maps of the 11 most representative drugs employed for COVID treatment.
    CONCLUSION: The georeferenced conceptual maps produced in the present report allow not only to better understand the leading institutions in R&D in COVID-19 related drugs, but also to visualize their interactions and research relationships. This could offer, in addition to a coherent, organized multinational effort, the possibility of searching for other drugs that have been employed for other diseases and that, in terms of their conceptual relations, could represent some possibilities for treating the coronavirus SARS-2.
    Keywords:  COVID-19; drugs; experimental pharmacology; spatial bibliometric
    DOI:  https://doi.org/10.2174/2211738511666221019154949
  60. Bioengineering (Basel). 2022 Oct 10. pii: 539. [Epub ahead of print]9(10):
      Biodiesel can be produced from vegetable oils, animal fats, frying oils, and from microorganism-synthesized oils. These sources render biodiesel an easily biodegradable fuel. The aim of this work was to perform an advanced bibliometric analysis of primary studies relating to biodiesel production worldwide by identifying the key countries and regions that have shown a strong engagement in this area, and by understanding the dynamics of their collaboration and research outputs. Additionally, an assessment of the main primary feedstocks employed in this research was carried out, along with an analysis of the current and future trends that are expected to define new paths and methodologies to be used in the manufacture of biodegradable and renewable fuels. A total of 4586 academic outputs were selected, including peer-reviewed research articles, conference papers, and literature reviews related to biodiesel production, in the time period spanning from 2010 to 2021. Articles that focused on feedstocks for the production of biodiesel were also included, with a search that returned 330 papers. Lastly, 60 articles relating to biodiesel production via sewage were specifically included to allow for an analysis of this source as a promising feedstock in the future of the biofuel market. Via the geocoding and the document analyses performed, we concluded that China, Malaysia, and India are the largest writers of articles in this area, revealing a great interest in biofuels in Asia. Additionally, it was noted that environmental concerns have caused authors to conduct research on feedstocks that can address the sustainability challenges in the production of biodiesel.
    Keywords:  bibliometric analysis; biodiesel; biofuel; feedstocks; research articles; sustainability
    DOI:  https://doi.org/10.3390/bioengineering9100539
  61. Plast Reconstr Surg Glob Open. 2022 Oct;10(10): e4590
      The literature in scientific journals represents current standards for plastic surgery (PS) and new observations contributed by leaders in the field. Observations of these trends over time define our progress and document our ever-changing specialty. This study aims to assess the racial/ethnic and gender makeup of authors who have published on the topic of diversity in PS, and to define trends over time, as well as geographic and journal representation of these publications.Methods: Existing published literature was queried through PubMed with the search terms "plastic surgery" AND "diversity" from 2008 to 2021. The race/ethnicity and gender of collated authors were adjudicated using NamSor software. Trends over time regarding quantity and topics covered, as well as gender and race of authors of these publications, were identified.
    Results: A total of 208 papers were identified with our search strategy; 74 met inclusion criteria, representing 398 authors. White' non-Hispanic authors represented the majority of first authors (45%) and the majority of senior authors (54%). Black/African American authors comprised 18% first authors and 19% senior authors. Male authorship predominated, with 58% of first authorship and 64% of senior authorship.
    Conclusions: Publications on the topic of diversity have increased in recent years. Trends show a significant shift in authorship, with prevalence of white male contributions rising. Women constitute most authors on the topic of gender diversity. These findings provide important insight into who cares about diversity within our specialty and who shapes its future.
    DOI:  https://doi.org/10.1097/GOX.0000000000004590
  62. J Dent Sci. 2022 Oct;17(4): 1859-1863
      Scientometric analysis of a disease is often conducted to recognize research hotspots and investigate latest trends. In this brief report, we provide a scientometric overview of oral cancer research in Taiwan and mainland China. There were 1924 and 3853 articles on oral cancer research originating from Taiwan and mainland China, respectively. In Taiwan, the risk factors including areca/betel quid chewing, tobacco smoking, and alcohol use were the distinctive keywords. For basic research, genotype, reactive oxygen, p53, mitochondria and caspase-9 were the distinctive keywords. In mainland China, experiment methods such as genetic transfection, gene silencing, colony formation, tumor xenograft were the distinctive keywords. Epithelial mesenchymal transition, long untranslated RNA, protein function, uvomorulin, and Bcl-2 were the distinctive keywords of basic research. Collectively, we hope that these scientometric characteristics will aid clinicians and researchers for obtaining information on oral cancer and can be of guidance for future studies.
    Keywords:  Bibliometric; Citation analysis; Oral squamous cell carcinoma; Research hotspots; Risk factors
    DOI:  https://doi.org/10.1016/j.jds.2022.05.015
  63. J Contextual Behav Sci. 2022 Oct;26 56-62
      Gender, racial, and ethnic disparities persist in the scientific community despite increasing attention to research-related equity. Men publish in biomedical, scientific journals more frequently than women researchers and have more leadership roles (e.g., first authorship) in these submissions. Similar differences in scientific publishing appear among under-represented minority (URM) authors compared to White counterparts. These findings of authorship disparities are not consistent across all journals and may relate to mentorship variables. This study aimed to investigate gender and racial patterns of publishing and research mentorship within the Association for Contextual Behavioral Science (ACBS) community, including in the Journal of Contextual Behavioral Science (JCBS). Two hundred and eighty-two ACT for Professionals listserv members responded to the anonymous 31-item survey. Men reported significantly more publications and more first author manuscripts than women, both in scientific journals generally and in JCBS specifically. White versus URM respondents more frequently reported publishing in JCBS, but not in other scientific journals. There were no differences in the total number of barriers noted between men and women or between White respondents and URM respondents. The top barriers to publishing among all respondents were lack of time, institutional support, and funding. Women more frequently reported lack of adequate research mentorship or collaboration as a barrier to publishing in scientific journals, as well as in JCBS specifically; men more frequently reported experiencing publishing barriers related to embargos and not having research that was appropriate for JCBS. Identifying as the same gender as one's primary research mentor did not relate to any areas of training. However, participants whose race differed from their mentor were significantly more likely to report training in running a study and receiving positive encouragement. Being matched in terms of gender or race with one's mentor did not relate to publishing variables. Findings highlight the continued gender and racial disparities in publishing within the ACBS community and in JCBS. Recommendations for decreasing these differences through research mentorship and structured training efforts are provided.
    Keywords:  disparities; gender; mentorship; publishing; race
    DOI:  https://doi.org/10.1016/j.jcbs.2022.08.009
  64. Braz Dent J. 2022 Sep-Oct;33(5):pii: S0103-64402022000500046. [Epub ahead of print]33(5): 46-54
      This study outlines the profile of research productivity grant holders of the Conselho Nacional de Desenvolvimento Científico e Tecnológico [CNPq (National Council for Scientific and Technological Development)] in the field of pediatric dentistry. A cross-sectional study with data collected from the Brazilian academic curriculum vitae database. The eligibility criterion was being a research productivity grant holder in pediatric dentistry from 2018 to 2020. In the period of interest, 215 individuals were research productivity grant holders in the field of dentistry, 33 of whom had graduate degrees (specialization, master's or doctorate) in pediatric dentistry. The period of scientific production and work concluded of advising of scientific initiation, master, doctoral and post-doctoral degrees was 2010 to 2020. Descriptive analysis was performed and the Kruskal-Wallis test was used to analyze associations (5% significance level) between productivity grant level (2, 1D, 1C, 1B or 1A) and year of obtainment of the doctoral degree. The VOSviewer (version 1.6.17) was used to present graphically the interinstitutional collaborations. The sample was composed of Level 2 researchers (66.7%), women (66.7%), researchers linked to institutions in the southeastern region of Brazil (81.8%), with a doctoral degree concluded prior to 2002 (51.5%), began working as a professor at a higher education institution prior to 2007 (78.8%) and the title of full professor (45.5%). No significant association was found between productivity grant level and year of conclusion of the doctoral degree (p = 0.10). Median (interquartile range) of scientific articles was 119 (37-312). The prevalence of citations (57.52%) and JCR articles (62.76%) was higher among female researchers. In conclusion, CNPq research productivity grant holders in pediatric dentistry are essentially represented by females from the southeast region of the country (UFMG and USP). However, males have proportionally greater productivity.
    DOI:  https://doi.org/10.1590/0103-6440202205016
  65. Children (Basel). 2022 Sep 26. pii: 1471. [Epub ahead of print]9(10):
      This paper utilised bibliometric and scientometric indicators to assess the current state of research in psycholinguistics. A total of 32,586 documents in psycholinguistics were included from Scopus, WOS, and Lens between 1946 and 2022. The collected data were analysed using CiteSpace 5.8.R3 and VOSviewer 1.6.18. The results included tabulation, visualisation, and mapping for the past, present, and future directions of the field of psycholinguistics. We identified key authors, works, journals, and concepts in the existing evidence concerning (children's) language acquisition, production, comprehension, and dissolution. The study contributes to the systematic study of existing scholarship in the field of psycholinguistics by documenting the progress of the field and informing relevant researchers about the current state of the field of psycholinguistics. Having grouped the 32,586 documents in psycholinguistics, 12 clusters were identified. These include (1) examining individual difference in affective norm and familiarity account; (2) examining refractory effect in the role of Broca's area in sentence processing; (3) using eye movement to study bilingual language control and familiarity account; (4) exploring familiarity account through relative clauses; (5) the study of formulaic language and language persistence; (6) examining affective norm and sub-lexical effect in Spanish words; (7) examining lexical persistence in multiplex lexical networks; (8) the study of persistence through cortical dynamics; (9) the study of context effect in language learning and language processing; (10) the study of neurophysiological correlates in semantic context integration; (11) examining persistence as an acquisition norm through naming latencies; and (12) following a cross-linguistic perspective to study aphasic speakers.
    Keywords:  language acquisition; language comprehension; language dissolution; language production; psycholinguistics; scientometric review
    DOI:  https://doi.org/10.3390/children9101471
  66. J Palliat Med. 2022 Oct 27.
      Background: The evidence base to support palliative care clinical practice is inadequate and opportunities to improve the evidence base remain despite the field's rapid growth. Objective: The aim of this study was to examine current National Institutes of Health (NIH) funding of palliative medicine research and trends over time. Design: We sought to identify NIH funding of palliative medicine (2016-2020) in two stages: (1) we searched the NIH grant database, RePORTER, for grants with the keywords, "palliative care," "end-of-life care," "hospice," and "end of life," and (2) identified palliative care researchers likely to have secured NIH funding using three strategies. Methods: We abstracted (1) the first and last authors' names from original investigations published in major palliative medicine journals from 2016 to 2018; (2) names from a PubMed-generated list of original articles published in major medicine, nursing, and subspecialty journals using the above keywords; and (3) palliative medicine journal editorial board members and members of key palliative medicine initiatives. We cross-matched the pooled names against NIH grants funded from 2016 to 2021. Results: A crosswalk analysis of the author search and NIH RePORTER search identified 1658 grants. Of those, 541 were categorized as relevant to palliative medicine, which represented 419 unique principal investigators (mean of 1.34 grants per investigator). Compared with 2011-2015, the number of NIH-funded grants increased by 25%, NIH dollars increased by 35%, and the distribution of grant types remained stable. Conclusions: Despite the challenging NIH funding climate, the number of NIH grants and funding to palliative care have increased. Given the increased funding allocation toward Alzheimer's dementia and related dementia research at the congressional level, this increase in funding reflects this funding allocation and does not represent overall growth. Dedicated federal funding for palliative care research remains critical to grow the evidence base for persons living with serious illnesses and their families.
    Keywords:  NIH; palliative medicine; research funding
    DOI:  https://doi.org/10.1089/jpm.2022.0316
  67. Int J Radiat Oncol Biol Phys. 2022 Jun 15. pii: S0360-3016(22)00597-1. [Epub ahead of print]
      PURPOSE: The Association of Residents in Radiation Oncology (ARRO) present the Educator of the Year Award to outstanding faculty members at each participating institution every year. The aim of this study was to characterize the recipients of this award.METHODS AND MATERIALS: The recipients of the annual ARRO Educator of the Year Award were identified from the years 2008-2019. Publicly available website domains were accessed to obtain data regarding clinical treatment site, number of sites treated, whether they were at the same institution where they trained, academic rank, gender, ASTRO fellow status, repeat awardee status during the time period and number of years since board certification. H- and m-indices were obtained from Scopus and calculated based on the time of the award. General workforce data was obtained from ASTRO and recently published articles. The authors performed correlative analyses stratified by gender and logistic regression to determine predictors of repeat awardee.
    RESULTS: There were a total of 607 ARRO educator awards from the years 2008-2019. The majority of recipients were male (77.6%) and assistant professors (39.0%). The median number of years from board certification was 7 (IQR 3-17) and the median h- and m-indices were 14 and 1, respectively. When stratified by gender, publication metrics were significantly higher for men (p<0.05) and men were more likely to be repeat awardees (p<0.001) and have higher academic rank (p=0.007). On multivariate analysis, those of higher rank were more likely to be repeat awardees (associate OR 3.55, p<0.001; full professor OR 2.04, p=0.046) and less likely to be women (OR 0.41; p=0.002), while h- and m-indices were not associated with repeat awardee status.
    CONCLUSIONS: Recipients of the ARRO educator award appear to be diverse in rank and experience however, associate professor rank and gender was associated with continued recognition of educational excellence.
    Keywords:  academic promotion; radiation oncology; resident education; teaching award
    DOI:  https://doi.org/10.1016/j.ijrobp.2022.05.049
  68. Heliyon. 2022 Oct;8(10): e10874
      Background: Rosacea is a common and complex chronic inflammatory skin disorder, the pathophysiology and etiology of which remain unclear. Recently, significant new insights into rosacea pathogenesis have enriched and reshaped our understanding of the disorder. A systematic analysis based on current studies will facilitate further research on rosacea pathogenesis.Objective: To establish an international core outcome and knowledge system of rosacea pathogenesis and develop a challenge, trend and hot spot analysis set for research and clinical studies on rosacea using bibliometric analysis and data mining.
    Methods: A search of the WoS, and PubMed, MEDLINE, Embase and Cochrane collaboration databases was conducted to perform visual bibliometric and data analysis.
    Results: A total of 2,654 studies were used for the visualization and 302 of the 6,769 outcomes for data analysis. It reveals an increased trend line in the field of rosacea, in which its fast-growing pathogenesis attracted attention closely related to risk, comorbidity and therapeutic strategies. The rosacea pathogenesis has undergone the great development on immunology, microorganisms, genes, skin barriers and neurogenetics. The major of studies have focused on immune and microorganisms. And keyword visualization and data analyses demonstrated the cross-talk between cells or each aspect of pathogenesis, such as gene-gene or gene-environment interactions, and neurological mechanisms associated with the rosacea phenotype warrant further research.
    Limitations: Inherent limitations of bibliometrics; and reliance on research and retrospective studies.
    Conclusions: The understanding of rosacea's pathogenesis has been significantly enhanced with the improved technology and multidisciplinary integration, but high-quality, strong evidence in favor of genomic and neurogenic requires further research combined with a better understanding of risks and comorbidities to guide clinical practice.
    Keywords:  Bibliometric analysis; Comorbidity; Data mining study; Pathogenesis; Risk factors; Rosacea; Treatment
    DOI:  https://doi.org/10.1016/j.heliyon.2022.e10874
  69. Nutrients. 2022 Oct 14. pii: 4275. [Epub ahead of print]14(20):
      The current bibliometric review evaluated recent papers that researched dietary protein sources to generate antidiabetic bioactive peptides/hydrolysates for the management of diabetes. Scopus and PubMed databases were searched to extract bibliometric data and, after a systematic four-step process was performed to select the articles, 75 papers were included in this review. The countries of origin of the authors who published the most were China (67%); Ireland (59%); and Spain (37%). The journals that published most articles on the subject were Food Chemistry (n = 12); Food & Function (n = 8); and Food Research International (n = 6). The most used keywords were 'bioactive peptides' (occurrence 28) and 'antidiabetic' (occurrence 10). The most used enzymes were Alcalase® (17%), Trypsin (17%), Pepsin, and Flavourzyme® (15% each). It was found that different sources of protein have been used to generate dipeptidyl peptidase IV (DPP-IV), α-amylase, and α-glucosidase inhibitory peptides. In addition to antidiabetic properties, some articles (n = 30) carried out studies on multifunctional bioactive peptides, and the most cited were reported to have antioxidant and antihypertensive activities (n = 19 and 17, respectively). The present review intended to offer bibliometric data on the most recent research on the production of antidiabetic peptides from dietary proteins to those interested in their obtention to act as hypoglycemic functional ingredients. The studies available in this period, compiled, are not yet enough to point out the best strategies for the production of antidiabetic peptides from food proteins and a more systematic effort in this direction is necessary to allow a future scale-up for the production of these possible functional ingredients.
    Keywords:  DPP-IV; hypoglycemic bioactive peptides; inhibitory peptides; protein hydrolysis; α-amylase; α-glucosidase
    DOI:  https://doi.org/10.3390/nu14204275
  70. Braz Oral Res. 2022 ;pii: S1806-83242022000100299. [Epub ahead of print]36 e0116
      This was a retrospective cohort study to investigate the impact of COVID-19 pandemic on the gender gap in articles submitted to three international dental journals based in Brazil. All submissions performed to Brazilian Dental Journal, Brazilian Oral Research, and Journal of Applied Oral Science before (2019) and during the pandemic (2020) were assessed. Gender of the first, last, and corresponding authors were collected. Other variables collected were journal, continent studied by authors and stage of their careers (classified according to authors' highest degree), and final decision reached in the article. Absolute and relative frequencies with 95% confidence intervals, Pearson's Chi-square tests, and Fisher's Exact test were used (α = 0.05). In total, 4,726 unique submissions were analyzed. A higher proportion of early-career authors was observed during the pandemic (44.8% to 49.3%, p = 0.021). Most articles were rejected but without association with gender. Increased proportion of male first authors from before to during the pandemic was observed (39% to 42.1%, p = 0.034). Drop in the proportion of articles with women as first authors was observed for researchers in their early- (65.9% to 58.8%, p = 0.02) and mid-career stages (63% to 55.8%, p = 0.014). Reduction in women as first authors was observed during the pandemic in South and Central Americas (66.7% to 61.5%, p = 0.010), and when the last author was a female, or the corresponding author was a male. In conclusion, a disproportionate impact on female dental researchers in submitting articles in the period from before to during the pandemic was observed when considering first authorship, suggesting that the COVID-19 may have increased the gender inequality in dental science.
    DOI:  https://doi.org/10.1590/1807-3107bor-2022.vol36.0116
  71. Einstein (Sao Paulo). 2022 ;pii: S1679-45082022000100408. [Epub ahead of print]20 eRW0113
      INTRODUCTION: Pulmonary neuroendocrine tumors account for approximately 20% of all primary lung tumors. Few studies summarize the current body of pulmonary neuroendocrine tumors studies worldwide.OBJECTIVE: A quantitative scientometric analysis was conducted to evaluate the development of applications and innovations and to analyze their contribution to various areas of improvement in treatment and diagnosis of pulmonary neuroendocrine tumors.
    METHODS: We searched for studies published in the last 20 years in the databases United States National Library of Medicine (PubMed), Scientific Electronic Library Online (SciELO), Scopus, and Web of Science, using the terms 'pulmonary neuroendocrine tumors', 'bronchial neuroendocrine tumors', 'bronchial carcinoid tumors', 'pulmonary carcinoid', 'typical pulmonary carcinoid', 'atypical pulmonary carcinoid', 'pulmonary carcinoid and diagnosis', 'pulmonary carcinoid and treatment', 'pulmonary carcinoid and epidemiology' and 'pulmonary carcinoid and prognosis'.
    RESULTS: Our results showed the number of publications increased significantly over the study period and was strongly associated with the economic or financial situation of the publications' countries of origin. We observed a predominance of studies on histological diagnosis compared to treatment, and among the studies related to treatment, a predominance of retrospective studies relative to prospective studies was found.
    CONCLUSION: Based on the published literature, we concluded research on pulmonary neuroendocrine tumors still seems to be incipient, because it favors studies related to histological characterization of the disease, and therapeutic studies are still predominantly of a retrospective nature.
    DOI:  https://doi.org/10.31744/einstein_journal/2022RW0113
  72. PLoS One. 2022 ;17(10): e0276616
      Openings for an assistant professor often attract a hundred or more applicants. This allows hiring committees to select highly productive candidates based on their number of publications. Applicants with more rapid publication would be hired with little or no postgraduate experience, but those with slower rates of publication would need more postgraduate experience. Our results show an association of more postgraduate experience, slower rates of publication, a smaller research group, and slower promotion when years are measured from PhD granting; conversely little or no postgraduate experience is generally associated with more rapid publication, a larger research group, and faster promotion. These results suggest the unexpected result that the number and rate of publication have opposite effects on the years from PhD granting to promotion which parametric survival analysis using a log-logistic distribution with gamma frailty confirmed. Statistical analysis revealed that number and rate of publication are reciprocal suppressor variables which were individually weaker predictors of years to promotion, but much more powerful when combined. Intuitively, this is probably because number and rate of publication contain information about other variables with: (1) number of publications being associated with more postgraduate experience, a smaller research group, and slower rates of publication; and (2) rate of publication being associated with a larger research group, and less postgraduate experience. Further, we found that promotion committees closely follow institutional tenure policy requiring promotion a fixed number of years after hiring as an assistant professor which may partially explain why promotion committees fail adjust the number and rate of publication for research group size as fairness in promotion might favor. Our results suggest that both postgraduate experience and research group size influence a professor's career.
    DOI:  https://doi.org/10.1371/journal.pone.0276616
  73. Vox Sang. 2022 Oct 25.
      BACKGROUND AND OBJECTIVES: A 2019 study highlighted significant gender inequities among blood banking and transfusion medicine (BBTM) journal editorial boards. We sought to assess if the representation of women has improved in the intervening 3 years.MATERIALS AND METHODS: We analysed the gender composition of nine BBTM journal editorial boards as of 13 September 2022, including the seven journals studied in 2019. We compared this to the proportion of females (term used by authors) on seven BBTM journal editorial boards in 2019 to assess change in the editorial board composition. We also assessed gender composition by editorial position (editor-in-chief [EIC], associate/assistant/titled editors and editorial board members).
    RESULTS: Nine BBTM journals have a total of 398 editorial positions and comprise significantly more men than women (68.8%, 274/398 vs. 31.2%, 124/398; p < 0.001). Among the seven journals analysed in 2019, the proportion of women on these seven editorial boards has remained unchanged (2019: 30.1%, 81/269 vs. 2022: 31.9%, 103/323; p = 0.66) despite the addition of 54 editorial positions.
    CONCLUSION: Women remain inequitably represented on journal editorial boards among all journal editorial positions. Although advocacy efforts are increasing, there has been limited improvement in gender equity in 3 years, despite a 20% increase in editorial positions.
    Keywords:  biomedical journals; diversity; editorial boards; gender equity; inclusion; transfusion medicine
    DOI:  https://doi.org/10.1111/vox.13371
  74. Healthcare (Basel). 2022 Oct 20. pii: 2098. [Epub ahead of print]10(10):
      Prospect Theory (PT) is an alternative, dynamic explanation of the phenomenon of risky decision making. This research presents an overview of PT's history in health fields, including advancements, limitations, and bibliometric data. A systematic and bibliometric review of the scientific literature included in the psychological categories of Web of Science (WoS) was performed following the PRISMA 2020 statement for systematic reviews. A total of 37 studies (10 non-empirical and 27 empirical) were included in the sample. Bibliometric results showed thematic variability and heterogeneity regarding the production, researchers, and methodologies that are used to study PT. The systematic results highlight three main fields of PT research: preventive and screening behaviors, promotion of healthy habits, and COVID-related decision making. Personal and contextual factors which alter the usual pattern specified by PT are also described. To conclude, PT currently has an interdisciplinary character suitable for health promotion, with recent studies broadening its applicability.
    Keywords:  applied psychology; behavior; decision making; health; prevention; prospect theory
    DOI:  https://doi.org/10.3390/healthcare10102098
  75. Scientometrics. 2022 Oct 17. 1-34
      Reporting guidelines are tools to help improve the transparency, completeness, and clarity of published articles in health research. Specifically, the CONSORT (Consolidated Standards of Reporting Trials) and SPIRIT (Standard Protocol Items: Recommendations for Interventional Trials) statements provide evidence-based guidance on what to include in randomised trial articles and protocols to guarantee the efficacy of interventions. These guidelines are subsequently described and discussed in journal articles and used to produce checklists. Determining the online impact (i.e., number and type of links received) of these articles can provide insights into the dissemination of reporting guidelines in broader environments (web-at-large) than simply that of the scientific publications that cite them. To address the technical limitations of link analysis, here the Debug-Validate-Access-Find (DVAF) method is designed and implemented to measure different facets of the guidelines' online impact. A total of 65 articles related to 38 reporting guidelines are taken as a baseline, providing 240,128 URL citations, which are then refined, analysed, and categorised using the DVAF method. A total of 15,582 links to journal articles related to the CONSORT and SPIRIT initiatives were identified. CONSORT 2010 and SPIRIT 2013 were the reporting guidelines that received most links (URL citations) from other online objects (5328 and 2190, respectively). Overall, the online impact obtained is scattered (URL citations are received by different article URL IDs, mainly from link-based DOIs), narrow (limited number of linking domain names, half of articles are linked from fewer than 29 domain names), concentrated (links come from just a few academic publishers, around 60% from publishers), non-reputed (84% of links come from dubious websites and fake domain names) and highly decayed (89% of linking domain names were not accessible at the time of the analysis). In light of these results, it is concluded that the online impact of these guidelines could be improved, and a set of recommendations are proposed to this end.Supplementary Information: The online version contains supplementary material available at 10.1007/s11192-022-04542-z.
    Keywords:  Altmetrics; Article-level metrics; CONSORT; Clinical trials; Link analysis; Online impact; Reporting guidelines; SPIRIT; Scientific impact; Webometrics
    DOI:  https://doi.org/10.1007/s11192-022-04542-z
  76. Medicina (Kaunas). 2022 Oct 13. pii: 1449. [Epub ahead of print]58(10):
      Introduction: Cutaneous squamous cell carcinoma (cSCC) is one of the most frequently occurring types of cancer in humans. Scientometric research is an innovative method for analyzing the research trends in various domains, with great implications in the field of medicine. Materials and Methods: We searched the Web of Science database with the following established query terms: "Squamous cell carcinoma", "skin", and "immunohistochemistry". After applying the inclusion and exclusion criteria, a total of 76 articles were selected. The present study aims to analyze, based on the frequency of use of keywords with scientometric algorithms and map-based distributions, the trends of the research concerning cSCCs in 2017-2022. Results: A graphical representation based on 11 scientometric maps presented the division of the keywords into seven clusters, from which seven categories of research interest were defined. The clusters represent a multidisciplinary approach to the diagnosis and treatment of cSCCs, cancer diagnostics, patient outcomes, histopathological importance, management of cSCCs, role of progression, and adequate treatment of and importance of immunohistochemistry for cSCCs. The distribution of the citations shows the importance of the available research on cSCCs by analyzing the first five most-cited articles included in our study in direct concordance with the seven defined clusters. Conclusion: The scientometric research method reveals the interest of research in the multidisciplinary approach used to obtain the best outcomes for the patient, including a targeted investigation, as well as diagnostic and treatment options. The trends in the research reveal that histopathological diagnostics and immunohistochemistry, combined with molecular techniques, are the most important tools used to establish a personalized diagnosis, thus increasing the quality of life and life expectancy for patients with cSCCs.
    Keywords:  dermatology; histopathology; immunohistochemistry; scientometry; squamous cell carcinoma
    DOI:  https://doi.org/10.3390/medicina58101449
  77. JAMA Netw Open. 2022 Oct 03. 5(10): e2238520
      Importance: Diverse research teams are critical to solving complex health problems and producing high-quality medical research.Objective: To examine the associations of student sex and racial and ethnic identity with publication rates during medical school.
    Design, Setting, and Participants: This cohort study assessed individual-level data of US MD graduates from medical school who matriculated in academic years 2014 to 2015 and 2015 to 2016. Data were obtained from the Association of American Medical Colleges and analyzed from October 2021 to January 2022.
    Main Outcomes and Measures: Outcomes of interest included students' self-reported participation in unique research experiences, number of publications, and computed publications per research experience. Poisson regressions were constructed to determine the association of sex and racial and ethnic identity with research outcomes using adjusted rate ratios (aRRs).
    Results: Among 31 474 graduates, 15 159 (48.2%) identified as women and 4344 (13.8%) identified as underrepresented in medicine by race and ethnicity (URIM; including American Indian, Alaska Native, Black, Hawaiian Native, Hispanic/Latinx, and Pacific Islander individuals). Students who attended National Institutes of Health (NIH) top 40 research-ranked schools reported higher number of research experiences and publication counts, resulting in a higher publication rate compared with students from non-top 40 schools (median [IQR] 1.60 [1.00-3.00] vs 1.25 [0.50-2.33]; P < .001). Women reported a higher number of research experiences than men but a significantly lower number of publications (top 40 schools: aRR, 0.89; 95% CI, 0.87-0.90; non-top 40 schools: aRR, 0.93; 95% CI, 0.92-0.95). This resulted in a significantly lower publication rate among women (top 40 schools: aRR, 0.85; 95% CI, 0.83-0.86; non-top 40 schools: aRR, 0.91; 95% CI, 0.90-0.92). Compared with White students, Asian students had higher publication rates at both NIH top 40 schools (aRR, 1.10; 95% CI, 1.08-1.12) and non-top 40 schools (aRR, 1.07; 95% CI, 1.05-1.08), while lower publication rates were reported among Black students (top 40 schools: aRR, 0.83; 95% CI, 0.80-0.86; non-top 40 schools: aRR, 0.88; 95% CI, 0.85-0.95) and Hispanic students attending non-top 40 schools (aRR, 0.93; 95% CI, 0.90-0.95).
    Conclusions and Relevance: These findings illustrate that inequities in the physician-scientist workforce began early in training and highlight key areas for intervention, such as funding support and mentorship training during undergraduate medical education, that may promote the future success of a diverse physician-scientist workforce.
    DOI:  https://doi.org/10.1001/jamanetworkopen.2022.38520
  78. PLoS One. 2022 ;17(10): e0270618
      The present processes of research assessment, i.e. focusing on one or a few, related, scientometrics, foster questionable authorship practices, like gifting authorship to non-contributing people. An especially harmful one of these unethical practices is the formation of publication cartels, where authors offer gift authorship to each other reciprocally. Here, by developing a simple model and a simulation of the publication process I investigate how beneficial cartels can be and what measure can be used to restrict them. My results indicate that publication cartels can significantly boost members' productivity even if paper counts are weighted by the inverse of author number (the 1/n rule). Nevertheless, applying the 1/n rule generates conflicts of interest both among cartel members themselves and between cartel members and non-members which might lead to the self-purification of the academic publishing industry.
    DOI:  https://doi.org/10.1371/journal.pone.0270618