bims-evares Biomed News
on Evaluation of research
Issue of 2022‒11‒20
58 papers selected by
Thomas Krichel
Open Library Society
  1. Research Hotspots and Emerging Trends of Facial Rejuvenation: A Bibliometric Analysis.
  2. Trends in the Extracorporeal Membrane Oxygenation Literature: A Bibliometric Analysis in the COVID-19 Era.
  3. Mapping knowledge structure and research trends of knee osteoarthritis with meniscus in two decades: A bibliometric analysis.
  4. Trends in immune-related adverse events for colorectal cancer: A bibliometric analysis.
  5. Estimates of global research productivity in primary ovarian insufficiency from 2000 to 2021: Bibliometric analysis.
  6. The application of tranexamic acid in joint arthroplasty: A 20-year bibliometric analysis.
  7. Knowledge mapping and current trends of immunotherapy for prostate cancer: A bibliometric study.
  8. Bibliometric analysis of tumor necrosis factor in post-stroke neuroinflammation from 2003 to 2021.
  9. A Bibliometric Analysis of the Top 100 Most Influential Articles on Cerebral Cavernous Malformations.
  10. Treatment on patients with spastic cerebral palsy in the past 30 years: A systematic review and bibliometric analysis.
  11. A worldwide bibliometric analysis of triptolide research from 1997 to 2021.
  12. Research trends in the field of retinitis pigmentosa from 2002 to 2021: a 20 years bibliometric analysis.
  13. Trends in authorship characteristics and collaboration in pharmacy practice publications: 2011-2020.
  14. The Hirsch-index in self-citation rates with articles in Medicine (Baltimore): Bibliometric analysis of publications in two stages from 2018 to 2021.
  15. Research trends and hotspots in the relationship between outdoor activities and myopia: A bibliometric analysis based on the web of science database from 2006 to 2021.
  16. Trends and frontiers in natural products for arthritis, 2000-2021: A bibliometric analysis.
  17. The top-100 cited articles on post-traumatic stress disorder: a historical bibliometric analysis.
  18. Bibliometric analysis of contributions to COVID-19 research in Malaysia.
  19. Dynamic structures and emerging trends in the management of major trauma: A bibliometric analysis of publications between 2012 and 2021.
  20. A bibliometric analysis of PIN1 and cell death.
  21. A bibliometric review on the top 20 cited articles in the Jackson heart study.
  22. Research trends and frontiers on antiphospholipid syndrome: A 10-year bibliometric analysis (2012-2021).
  23. Bibliometric and visual analysis of mesenchymal stem cells in the treatment of osteoporosis based on CiteSpace software.
  24. Trends in research related to menopausal hormone therapy from 2000 to 2021: A bibliometric analysis.
  25. Knowledge mapping of the links between the microbiota and allergic diseases: A bibliometric analysis (2002-2021).
  26. The use of radar plots with the Yk-index to identify which authors contributed the most to the journal of Medicine in 2020 and 2021: A bibliometric analysis.
  27. Contributions toward sustainable development: a bibliometric analysis of sustainability reporting research.
  28. Nutrition and sarcopenia: Current knowledge domain and emerging trends.
  29. Bibliometric analysis of research on gene expression in spinal cord injury.
  30. Knowledge mapping of copper-induced cell death: A bibliometric study from 2012 to 2022.
  31. A retrospective analysis of schistosomiasis related literature from 2011-2020: focusing on the next decade.
  32. Journal of family medicine and primary care- A five year bibliometric analysis from 2016 to 2020.
  33. Health research in the state of Odisha, India: A decadal bibliometric analysis (2011-2020).
  34. Global academic output on COVID-19 and Guillain-Barre Syndrome: A bibliometric analysis.
  35. In Search of an Academic "Greatest Hits" Album: An Examination of Bibliometrics and Bibliometric Web Platforms.
  36. Emerging trends and focus of giant cell tumor of bone research from 2001-2021: A visualization research.
  37. Cancer research activity in the Arab world: a 15-year bibliometric analysis.
  38. Systematic bibliometric and visualized analysis of research hotspots and trends on the application of artificial intelligence in diabetic retinopathy.
  39. Knowledge domain and hotspot trends in coal and gas outburst: a scientometric review based on CiteSpace analysis.
  40. Trends in metabolic signaling pathways of tumor drug resistance: A scientometric analysis.
  41. Bibliometric analysis of COVID-19 publications shows the importance of telemedicine and equitable access to the internet during the pandemic and beyond.
  42. Dynamics of Acute Postsurgical Pain over the Last Decade: A Bibliometric Analysis.
  43. Hotspots and trends of biological water treatment based on bibliometric review and patents analysis.
  44. From Deutsche Zeitschrift to International Journal of Legal Medicine-100 years of legal medicine through the lens of journal articles : Part 2: Deutsche Zeitschrift für die gesamte gerichtliche Medizin from 1948 to 1969.
  45. Malaysian Disaster Medicine Research: A Bibliographic Study of Publication Trends.
  46. Corrigendum: Global tendency and frontiers of research on myopia from 1900 to 2020: A bibliometrics analysis.
  47. Gender and Ethnic Diversity in Academic Facial Plastic Surgery.
  48. Is novel research worth doing? Evidence from peer review at 49 journals.
  49. Bibliometric analysis of an important diagnostic technique for the treatment of breast cancer.
  50. Topic Analysis and Mapping of Tuberculosis Research Using Text Mining and Co-Word Analysis.
  51. Analyzing and mapping the research status, hotspots, and frontiers of biological wound dressings: An in-depth data-driven assessment.
  52. Contextualizing Gender Disparity in Editorship in Psychological Science.
  53. Beyond the Citation Counts: An Insight into Altmetrics.
  54. Cassava starch films for food packaging: Trends over the last decade and future research.
  55. [PUBLICATION LANDSCAPE OF THE MOSCOW MEDICINE SCIENCE].
  56. Selected Trends in Psychotherapy Research: An Index Analysis of RCTs.
  57. Correction: Trends and focuses of hantavirus researches: a global bibliometric analysis and visualization from 1980 to 2020.
  58. A decade of population genetics studies of scleractinian corals: A systematic review.
  1. Aesthetic Plast Surg. 2022 Nov 14.
    Research Hotspots and Emerging Trends of Facial Rejuvenation: A Bibliometric Analysis.
    JiaXin Mao, CholSik Ri, Bo Li, XiaoYu Zhu, MuXin Zhao.
      BACKGROUND: In recent years, the demand for facial rejuvenation is increasing year by year. This study aims to use bibliometric analysis to construct a visualization map of the facial rejuvenation research and provide the research hotspots and trend frontiers in the field.METHODS: Publications on facial rejuvenation research were extracted from the Web of Science Core Collection database. VOSviewer 1.6.18 was used to analyze the co-authorship, the citations of countries, institutions, and authors, the co-occurrence of keywords, and the journals in which the studies were published.
    RESULTS: In total, 6,196 records of facial rejuvenation research published between 2000 and 2021 were collected. The USA had published the most publications in this field (2,647), and its main partners were Canada, Germany, and China. University of California, Los Angeles, was the institution with the greatest contribution (127 publications). Plastic and Reconstructive Surgery (623 publications) published the most research in this field and was also the most frequently co-cited journal (17,349 citations, total link strength: 586,955). Rohrich RJ (70 publications) was the most prolific and most frequently co-cited author (1,230 citations, TLS: 26,603). Among the 100 most cited articles, 57 articles are amenable to grading level of evidence, and most papers presented their findings utilizing level IV evidence.
    CONCLUSIONS: At present, the research hotspots in this field included the following six aspects: facial photoelectric therapy, aging manifestation and treatment in the middle of the face, the application of autologous fat transfer in facial rejuvenation, facial plastic surgery, facial injection cosmetology, and rhytidectomy and related anatomy. According to the analysis of the timing diagram, the research trends were esthetic medicine, mesenchymal stem cells, laser therapy, the application of platelet-rich plasma, and platelet-rich fibrin. This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.
    LEVEL OF EVIDENCE III: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
    Keywords:  Bibliometric Analysis; Facial Aging; Facial Rejuvenation; Hotspots; Trends
    DOI:  https://doi.org/10.1007/s00266-022-03099-9
  2. J Extra Corpor Technol. 2022 Mar;54(1): 19-28
    Trends in the Extracorporeal Membrane Oxygenation Literature: A Bibliometric Analysis in the COVID-19 Era.
    Aashray K Gupta, Lachlan D Kerr, Brandon Stretton, Joshua G Kovoor, Christopher D Ovenden, Joseph N Hewitt, Justin C Y Chan.
      Extracorporeal Membrane Oxygenation (ECMO) was first used in the 1970s. Its use is increasingly common in critical care and perioperative settings and has gained newfound prominence during COVID-19. To guide future research, we conducted a bibliometric analysis of ECMO literature. Thomson Reuters Web of Science was searched to March 7, 2021. Articles were ranked by total number of citations. Data was extracted from the 100 most cited papers relevant to ECMO for study design, topic, author, year, and institution. Journal impact factor for 2019 and Eigenfactor scores were also recorded. Our search retrieved a total of 18,802 articles. Median number of citations for the top 100 articles was 220 (range 157-1,819). These were published in 34 journals, with first authors originating from 15 countries. The Annals of Thoracic Surgery had the highest number of articles (n = 9) while Lancet publications had the most citations (n = 3,191). Use of ECMO was most commonly observed in cardiogenic shock or acute respiratory distress syndrome. United States had the greatest article output (n = 49). With 10 publications, 2013 was the most prolific year. Using linear regression, when controlled for time since publication, there was no statistically significant relationship between 2019 journal impact factor and number of article citations (p = .09). Top articles in the ECMO literature are of considerable impact and quality. As the United States produced the bulk of the prominent evidence base, and most data were regarding respiratory issues, outsized advances in ECMO may be possible within the United States during the COVID-19 era.
    Keywords:  COVID-19; bibliometric analysis; extracorporeal membrane oxygenation; mortality.; outcomes
    DOI:  https://doi.org/10.1182/ject-19-28
  3. Front Surg. 2022 ;9 939003
    Mapping knowledge structure and research trends of knee osteoarthritis with meniscus in two decades: A bibliometric analysis.
    Weijian Chen, Yaqin Yang, Gangjian Tang.
      Background: Knee osteoarthritis (KOA) is a chronic degenerative disease that is closely related to the meniscus. Currently, no bibliometric studies have jointly analyzed KOA and the meniscus. This study aimed to provide a comprehensive analysis of the knowledge structure of KOA and the meniscus across two decades and to identify the emerging research trends from a bibliometric perspective.Methods: All articles reporting KOA and the meniscus from 2001 to 2021 were obtained from the Web of Science Core Collection. R software, CiteSpace, VOS Viewer, and Microsoft Excel were used to analyze the publications including the authors, cited authors, journals, cited journals, country of research, institutions, and research focus. These data were used to generate visual knowledge maps of the outputs.
    Results: A total of 3,218 articles were retrieved. Guermazi was identified as the author who had contributed the most to the field and Osteoarthritis and Cartilage was identified as the most productive research journal. The United States is the global leader in the field and the center for international cooperation with less international collaboration occurring in Eastern Asia. Boston University was the most prolific institution. According to the data, "articular-cartilage," "meniscectomy," "follow-up," "anterior cruciate ligament," and "cartilage" were identified as research hotspots in the field. "Consequences," "prognostic-factors," and "receptor" were predicted as future hot topics of research.
    Conclusions: This study is the first comprehensive bibliometric study to jointly analyze KOA and the meniscus. Our data enable a better understanding of research trends and identify research hotspots and gaps in knowledge across the field. Our findings provide practical information for researchers to better understand the key research areas and identify the research frontiers and future hot topics.
    Keywords:  bibliometrics [MeSH]; knee osteoarthritis (KOA); meniscus; research trends; visualized study
    DOI:  https://doi.org/10.3389/fsurg.2022.939003
  4. Front Oncol. 2022 ;12 1024321
    Trends in immune-related adverse events for colorectal cancer: A bibliometric analysis.
    Jin Cui, Ying Xiong, Min Sun, Xinyue Gu, Yuting Liu, Luhui Zhong, Xiaohua Hong, Li Liu.
      Purpose: We used bibliometric methods to assess the global scientific output on the IRAEs for colorectal cancer and to explore the current status and trends in the field over the last three decades.Methods: Studies on immune-related adverse events for colorectal cancer published from 1996 to 2022 were retrieved from the Web of Science. For quantitative and qualitative assessments of publication outputs and author contributions, the R bibliometrix package was used. VOSviewer was used to construct networks based on the co-authorship of countries/institutions/authors, co-citation analysis of journals/references, citation analysis of documents, and co-occurrence of keywords.
    Results: A total of 237 relevant articles were included in the final analysis. The number of publications has increased significantly over time. The countries and institutions that contributed most to the field were the USA and the University of Texas MD Anderson Cancer Center. Jefferey Schlom was the most productive author, ranking first in cited authors. The most cited document was Topalian et al. in The New England Journal of Medicine (2012). The journals with the highest number of selected articles and citations were The New England Journal of Medicine and the Journal of Clinical Oncology, respectively. Co-occurrence analysis showed that IRAEs for colorectal cancer were associated with immunotherapy, open-label, chemotherapy, nivolumab, and PD-1. Trend analysis showed that immune checkpoint inhibitors, gut-microbiota, inflammatory-bowel disease, and PD-1has been on the rise in recent years to IRAEs for colorectal cancer.
    Conclusion: Our bibliometric analysis showed that studying IRAEs for colorectal cancer is increasingly a hot topic. The focus of the research had evolved from traditional treatment modalities such as targeted therapy to gut microbiota. Inflammatory bowel disease may be a future research hotspot of IRAEs for colorectal cancer.
    Keywords:  adverse events; bibliometric analysis; co-occurrence; colorectal cancer; immune
    DOI:  https://doi.org/10.3389/fonc.2022.1024321
  5. Front Endocrinol (Lausanne). 2022 ;13 959905
    Estimates of global research productivity in primary ovarian insufficiency from 2000 to 2021: Bibliometric analysis.
    Xudong Zhang, Yimeng Lu, Shanshan Wu, Xinyang Zhao, Shuyu Li, Siwen Zhang, Jichun Tan.
      Background: Primary ovarian insufficiency (POI) is a heterogeneous disease with diverse clinical phenotypes and etiologies, which is defined as ovarian dysfunction under the age of 40 years. The global prevalence of POI is approximately about 1.1%, and it severely affects female fertility. Nevertheless, bibliometric analysis in this field is extremely limited. We aimed to visualize the research hotspots and trends of POI using bibliometric analysis and tried to predict the future development of this field.Methods: The original articles regarding POI were culled from the Web of Science Core Collection. Countries, institutions, journals, authors, and keywords in this field were visually analyzed by employing CiteSpace software and Microsoft Excel 2021 software.
    Results: A total of 2,999 publications were included for further bibliometric analysis after screening the titles and abstracts stringently. The number of literature regarding POI significantly increased yearly. These publications come from 78 countries. The USA was dominant in the field of POI in terms of the number of publications (865), average citations per item (57.36), and h-index (112). The Institut National De La Sante Et De La Recherche Medicale Inserm is the most high-yield institution in this field with 351 publications. Fertility and Sterility ranked first with the highest number of publications (152), followed by Human Reproduction (138). According to the keyword cluster analysis from 2000 to 2021, the eight keyword clusters encountered frequently were apoptosis, osteoporosis, fertility preservation, mutation, fragile x syndrome, adrenal insufficiency, DNA repair, ovarian reserve. Keyword citation burst analysis revealed that whole-exome sequencing, ovarian tissue cryopreservation, and DNA repair had a citation burst until 2021.
    Conclusions: Great progress has been made in POI research over the past 20 years, which is widely researched but unevenly developed in the world. In terms of influence, the United States may be in the lead. The research hotspots in POI are mainly pathogenesis and treatment, including genetic mutation, hormone therapy, fertility preservation, and stem cell transplantation.
    Keywords:  Citespace; POF; POI; genetic mutation; premature ovarian insufficiency; stem cell transplantation
    DOI:  https://doi.org/10.3389/fendo.2022.959905
  6. Front Public Health. 2022 ;10 1013461
    The application of tranexamic acid in joint arthroplasty: A 20-year bibliometric analysis.
    Jun Zhang, Runhan Zhao, Yanran Huang, Chuang Xiong, Hao Liang, Habu Jiwa, Xiaoji Luo.
      Background: With the arrival of the era of the aging population, the amount of joint arthroplasty surgery keeps rising, and the articles related to the application of tranexamic acid (TXA) in joint arthroplasty (we called the application of tranexamic acid in joint arthroplasty as TIA in this study) also show a blowout growth. Therefore, we conducted a bibliometric analysis of TIA-related publications to identify the main research trends and hot spots in this field in the last 20 years.Methods: In this study, publications in the field of TIA from January 1, 2002 to December 31, 2021 were searched in the Web of Science Core Collection (WoSCC). A total of 1,013 publications were evaluated for specific characteristics with Microsoft Excel software, CiteSpace, VOSviewer, and Online Analysis Platform of Literature Metrology (http://bibliometric.com/).
    Results: A total of 1,013 TIA-related articles were included in this study, and the number of articles in this field has increased yearly over the past 20 years. The USA and China dominated in the field of TIA. The Sichuan University published the most TIA-related articles among all the institutions. Of all the authors, Professor Pei was the most productive author with 64 articles. The lack of international cooperation was a significant problem in this field during the past 20 years. Furthermore, the results of the co-citation analysis and citation bursts analysis revealed that the safety and effectiveness of TIA and the optimal use strategy were the main trends and hotspots for the current and future.
    Conclusion: This bibliometric study reviewed the evolution trend of TIA research, and identified the countries, institutions, authors and journals that have made significant contributions to this field in the past 20 years, as well as the limitations and deficiencies in this field. In addition, this study revealed that the effectiveness and safety of TIA and the optimal use strategy was the current or future research trend and hotspot in this field.
    Keywords:  bibliometric approach; hotspots; joint arthroplasty; tranexamic acid; trends
    DOI:  https://doi.org/10.3389/fpubh.2022.1013461
  7. Front Immunol. 2022 ;13 1014981
    Knowledge mapping and current trends of immunotherapy for prostate cancer: A bibliometric study.
    Weibo Zhong, Zefeng Shen, Yongxin Wu, Xiangming Mao, Jianqiu Kong, Weixia Wu.
      Background: Prostate cancer (PCa) is the second most common malignancy in men worldwide. Growing evidence substantiates the important role of immunotherapy in human tumors. Given that immunotherapy is often unsatisfactory on PCa, many studies have been conducted on PCa immunotherapy to improve treatment efficacy. However, no relevant bibliometric study of PCa immunotherapy has hitherto been reported. A bibliometric analysis was performed to evaluate the global scientific production of PCa immunotherapy research and characterize the development trends for future studies in this article.Methods: The publications related to PCa immunotherapy were extracted from the Web of Science Core Collection. The contribution and co-occurrence relationships of countries/regions, institutions, journals, references, authors, and keywords were assessed and visualized by VOSviewer and CiteSpace to identify research hotspots and potential future trends.
    Results: A total of 3,583 publications related to PCa immunotherapy from 1999 to 2021 were collected. The results of annual publications and citations exhibited a steady increase over the past 22 years. The National Cancer Institute in the USA published far more papers during the study than any institute. Accordingly, the USA had the most publications (n = 1,954, 54.54%). Gulley, James L. had the most number of published papers, and Small, Eric J. was the most co-cited authors in this field. Cancer Immunology Immunotherapy was the most productive journal, with 145 publications on PCa immunotherapy. Keyword cluster and keyword burst analyses showed that research in PCa immunotherapy shifted from "t cell infiltration" and "sipuleucel t" to "immune checkpoint inhibitor", "CTLA-4", and "PD-L1 expression".
    Conclusion: PCa immunotherapy has attracted much attention, reflected by the increasing number of annual publications and citations. Much emphasis has been placed on exploring the complex immunogenicity and tumor microenvironment for PCa and identifying the patient population who can benefit from immunotherapy. Combining immune checkpoint inhibitors with other therapeutic options and cancer vaccines represents the future development trends in PCa immunotherapy.
    Keywords:  bibliometric analysis; immune check inhibitor; immunotherapy; prostate cancer; sipuleucel-T
    DOI:  https://doi.org/10.3389/fimmu.2022.1014981
  8. Front Immunol. 2022 ;13 1040686
    Bibliometric analysis of tumor necrosis factor in post-stroke neuroinflammation from 2003 to 2021.
    Yang Zhao, Qihan Zhu, Chen Bi, Jichao Yuan, Yujie Chen, Xiaofei Hu.
      Objective: Tumor necrosis factor (TNF), a crucial cytokine, has important research value in post-stroke neuroinflammation (PSN). We analyzed the studies that have been conducted in this area and used bibliometric methods to predict research hotspots and identify trends regarding TNF in PSN.Methods: Publications were accessed at the Science Citation Index Expanded 1975-2021 (SCI expanded), Web of Science Core Collection (WoSCC), on May 1, 2022. Additionally, software such as CiteSpace and VOSviewer were utilized for bibliometric analyses.
    Results: In total, 1391 original articles and reviews on TNF in PSN published from 2003 to 2021 were identified. An upward trend was observed in the number of publications on TNF in PSN. These publications were primarily from 57 countries and 1446 institutions, led by China and the United States with China leading the number of publications (NP) and the US with the number of citations (NC). The League of European Research Universities (LERU) and Journal of Neuroinflammation, respectively were the most prolific branches and journals. Zhang, John H. published the most papers and Finsen, Bente had the most cited papers. One paper by Kettenmann, H. published in 2011 reached the highest level of Global Citation Score (GCS). The keyword co-occurrence and reference co-citation analyses suggest that poststroke therapy and potential mechanistic pathways are important topics related to PSN in recent years. Reference burst detection suggests new burst hotspots after 2015, focusing on pathway modulation and discovery of therapeutic targets, suggesting a substantial development in the study of TNF in PSN research.
    Conclusion: The present bibliometric analysis shows a continuous trend of increasing literature related to TNF in PSN, and shows that TNF plays an important role in PSN involves multiple immune mechanisms and may contribute as a potential target for neuroprotective therapeutics after stroke. Prior to 2011, most of the research was focused on discovering the specific role of TNF in PSN, and in recent years studies have mainly targeted the exploration of the signaling pathways. Future research prospects may lie in finding key therapeutic targets in pathway of TNF in PSN.
    Keywords:  CiteSpace; TNF; VOSviewer; bibliometric analysis; neuroinflammation; stroke
    DOI:  https://doi.org/10.3389/fimmu.2022.1040686
  9. World Neurosurg. 2022 Nov 14. pii: S1878-8750(22)01594-7. [Epub ahead of print]
    A Bibliometric Analysis of the Top 100 Most Influential Articles on Cerebral Cavernous Malformations.
    Lane Fry, Cody Heskett, Frank A De Stefano, Catherine Lei, Aaron Brake, Kevin Chatley, Koji Ebersole, Jeremy Peterson.
      OBJECTIVE: Cerebral cavernous malformations (CCM), or cavernomas, are low-flow sinusoidal vascular anomalies of the central nervous system comprised of capillary networks filled with blood in various stages of thrombosis. This bibliometric analysis summarizes the most-cited articles on CCM and highlights the contributing articles to today's evidence-based practice.METHODS: In the execution of this bibliometric-based review article, the Scopus database was used to perform a title-specific, keyword-based search for all publications until June 2022. The keyword "cerebral cavernous malformations" OR "cerebral cavernous hemangioma" OR "cerebral cavernous angioma" OR "cerebral cavernoma." was used. Our results were arranged in descending order based on the article's citation count. The 100 most-cited articles were selected for analysis. Parameters included the following: title, citation count, citations per year, authors, specialty of first author, institution, country of origin, publishing journal, Source Normalized Impact Per Paper (SNIP), and Hirsch index were collected.
    RESULTS: The keyword-based search showed that 806 articles were published between 1974 and 2022 on CCMs. The top 100 articles were published between 1980 and 2018. The top 100 most cited articles collected a total of 12,928 citations with an average of 129.3 citations per paper. The rate of self-citations accounted for an average of 2.79% of the total number of citations.
    CONCLUSION: The bibliometric analysis provides a quantitative overview of how medical topics and interventions are analyzed in academic medicine. In the present study, we evaluated the global trends in CCMs by analyzing the top 100 most cited papers.
    Keywords:  Carotid cavernous fistula; bibliometric analysis; neurosurgery
    DOI:  https://doi.org/10.1016/j.wneu.2022.11.042
  10. Medicine (Baltimore). 2022 Nov 11. 101(45): e30535
    Treatment on patients with spastic cerebral palsy in the past 30 years: A systematic review and bibliometric analysis.
    Dingfang Chen, Yuefeng Wu, HaiYing Li, Xue Pan, Jin Zhou.
      BACKGROUND: Over the past 30 years, treatments from different disciplines have been applied to spastic cerebral palsy (SCP). However, few bibliometric studies have been conducted to date. This study explored the knowledge base, emerging hotspots, and future trends related to SCP treatment research using bibliometric analysis.METHODS: Publications on SCP treatment included in the Web of Science Core Collection database between 1990 and 2020 were retrieved, and Medical Subject Headings terms were extracted from PubMed. Online bibliometric analysis website (http://bibliometric.com/), 2 pieces of software called "CiteSpace" and "VOSViewer" were used for quantitative analysis and knowledge map establishment.
    RESULTS: A total of 1668 papers were retrieved from 1990 to 2020. The number of publications has increased annually. Developmental Medicine and Child Neurology is the most productive and the highest co-cited journal. The United States has been the largest contributor. Vrije Universiteit Amsterdam ranked first in the number of papers published among institutions that have conducted correlational research. Becher JG and Graham HK should be considered scholars who have made outstanding contributions. The knowledge base of the SCP treatment research field is thoughtfully constructed to promote understanding of the field.
    CONCLUSION: This bibliometric study identified global achievements, research hotspots, and trends of SCP treatment. They provide insights into the research field and valuable information for future scientific research and clinical treatment.
    DOI:  https://doi.org/10.1097/MD.0000000000030535
  11. Am J Transl Res. 2022 ;14(10): 7290-7307
    A worldwide bibliometric analysis of triptolide research from 1997 to 2021.
    Bingzhou Ji, Zijun Cai, Di Liu, Yilan Ding, Yueyao Zhang, Shinen Naranmandakh, Cheng Huang, Wenfeng Xiao, Yusheng Li.
      OBJECTIVES: In recent years, triptolide has received much attention due to its wide range of pharmacological activities. However, no bibliometric studies have been published on triptolide. This study conducted a bibliometric study to provide scientific and insightful information for further research.METHODS: This study performed a bibliometric study of articles published in the Web of Science database from 1997 to 2021. Based on the keywords used in relation to the title of the article containing the word triptolide, 970 publications were searched for further analysis. We used Microsoft Excel for frequency analysis, VOSviewer and CiteSpace for data visualization, and Rstudio for citation metrics and analysis.
    RESULTS: After analysis, standard bibliometric indicators such as the growth of publications, prolific authors and coauthorship, country distributions, preferred journals, most influential institutions and top cited documents were presented in this study.
    CONCLUSIONS: According to our findings, the number of triptolide-related publications has been increasing since 2009. China was the largest contributor to triptolide research, followed by the USA. Biomedicine & Pharmacotherapy was the leading journal related to triptolide research. The most productive authors were Zhang LY (China Pharmaceut Univ) and Jiang ZZ (China Pharmaceut Univ). China Pharmaceutical University was the most influential institution in the field of triptolide research. Our findings suggest that the effective use of triptolide in cancer therapy as well as overcoming its multiorgan toxicity to promote its widespread clinical applications are expected to be hot research topics in the future.
    Keywords:  Bibliometric analysis; CiteSpace; Rstudio; VOSviewer; triptolide
  12. Int Ophthalmol. 2022 Nov 19.
    Research trends in the field of retinitis pigmentosa from 2002 to 2021: a 20 years bibliometric analysis.
    Feng Lin, Minyue Xie, Xiaonan Sheng, Lingxi Guo, Jinchao Jia, Yimin Wang.
      PURPOSE: To analyze publication trends for the past 20 years and identify potential research trends in the retinitis pigmentosa (RP) research field.METHODS: We extracted data from the Web of Science Core Collection and conducted a bibliometric analysis. All records related to RP from 2002 to 2021 were analyzed. The co-occurrence maps of keywords were generated by VOSviewer v.1.6.17 to identify knowledge structure and research trends in the RP research field.
    RESULTS: Totally 1976 publications from 2002 to 2021 were included in this study. The United States ranked first in the number of publications, citations and H-index. INVESTIGATIVE OPHTHALMOLOGY VISUAL SCIENCE was the most prolific journal in the RP research field. LEAGUE OF EUROPEAN RESEARCH UNIVERSITIES LERU had the greatest output in the RP research field. Tsang SH contributed to the highest number of publications in the RP research field. All keywords were divided into three clusters: (1) gene mutations, (2) pathophysiological changes, and (3) diagnosis and management in the RP research field. Average appearing years of keywords were evaluated and most of the recently appearing keywords focused on the pathophysiological changes.
    CONCLUSIONS: By bibliometric analysis, the knowledge structure of RP research field was identified. It may help clinicians to comprehensively understand the hotspots and guide the research trends in the RP research field.
    Keywords:  Bibliometric analysis; Knowledge structure; Retinitis pigmentosa (RP); VOSviewer
    DOI:  https://doi.org/10.1007/s10792-022-02581-2
  13. Res Social Adm Pharm. 2022 Nov 08. pii: S1551-7411(22)00391-6. [Epub ahead of print]
    Trends in authorship characteristics and collaboration in pharmacy practice publications: 2011-2020.
    Samuel Olusegun Adeosun.
      BACKGROUND: Research and scholarly publications are core expectations in academia that often require collaboration. While the number of authors per document (NAPD) has increased in every discipline, co-authorship culture and collaboration patterns vary among disciplines and countries.OBJECTIVES: To determine the trends in the patterns and characteristics of authorship and collaborations in United States' pharmacy practice faculty publications from 2011 to 2020.
    METHODS: Seven pharmacy practice journals were selected based on previous studies and data from Scimago Journal and Country Rank. Articles and reviews (document types) published during the decade were obtained from the Scopus database. Data cleaning and analysis were done using Microsoft Excel, R programming language packages, and VOSviewer. The Mann-Kendall trend test was used to determine the presence of (positive/negative) monotonic trends.
    RESULTS: Eight thousand and fifty-nine documents published in the selected journals (82.7% articles; 17.3% reviews) by 18,575 unique authors during the decade were analyzed. In most documents (69.3-78.7%), senior/corresponding authors were first authors. There were statistically significant upward trends in the mean NAPD (3.8 ± 2.2 to 4.7 ± 2.4), median NAPD, and related bibliometric indices (degree of collaboration, collaborative index, and collaborative coefficient). Conversely, productivity (document per unique author) significantly trended downward and had a strong, negative correlation with mean NAPD. The proportion of one-author publications also trended downward (12.2%-3.6%). Evidence also supports a downward trend in institutional collaboration and an upward trend in international collaboration.
    CONCLUSIONS: The assumption that last authors are senior authors does not hold in pharmacy practice publications. The increase in NAPD is not considered as authorship inflation, but rather an authorship "upcreep" that is driven by a survival strategy to publish together, predominantly within institutions rather than across institutions or countries. Therefore, faculty publication benchmarks should be crafted to mitigate the inverse relationship between collaboration and productivity, without discouraging collaboration.
    Keywords:  Authorship; Bibliometric; Collaboration; Pharmacy practice; Productivity; VOSviewer
    DOI:  https://doi.org/10.1016/j.sapharm.2022.11.002
  14. Medicine (Baltimore). 2022 Nov 11. 101(45): e31609
    The Hirsch-index in self-citation rates with articles in Medicine (Baltimore): Bibliometric analysis of publications in two stages from 2018 to 2021.
    Mei-Yuan Liu, Tsair-Wei Chien, Willy Chou.
      BACKGROUND: The Hirsch-index (h-index) is a measure of academic productivity that incorporates both the quantity and quality of an author's output. However, it is still affected by self-citation behaviors. This study aims to determine the research output and self-citation rates (SCRs) in the Journal of Medicine (Baltimore), establishing a benchmark for bibliometrics, in addition to identifying significant differences between stages from 2018 to 2021.METHODS: We searched the PubMed database to obtain 17,912 articles published between 2018 and 2021 in Medicine (Baltimore). Two parts were carried out to conduct this study: the categories were clustered according to the medical subject headings (denoted by midical subject headings [MeSH] terms) using social network analysis; 3 visualizations were used (choropleth map, forest plot, and Sankey diagram) to identify dominant entities (e.g., years, countries, regions, institutes, authors, categories, and document types); 2-way analysis of variance (ANOVA) was performed to differentiate outputs between entities and stages, and the SCR with articles in Medicine (Baltimore) was examined. SCR, as well as the proportion of self-citation (SC) in the previous 2 years in comparison to SC were computed.
    RESULTS: We found that South Korea, Sichuan (China), and Beijing (China) accounted for the majority of articles in Medicine (Baltimore); ten categories were clustered and led by 3 MeSh terms: methods, drug therapy, and complications; and more articles (52%) were in the recent stage (2020-2021); no significant difference in counts was observed between the 2 stages based on the top ten entities using the forest plot (Z = 0.05, P = .962) and 2-way ANOVA (F = 0.09, P = .76); the SCR was 5.69% (<15%); the h-index did not differ between the 2 collections of self-citation inclusion and exclusion; and the SC in the previous 2 years accounted for 70% of the self-citation exclusion.
    CONCLUSION: By visualizing the characteristics of a given journal, a breakthrough was made. Subject categories can be classified using MeSH terms. Future bibliographical studies are recommended to perform the 2-way ANOVA and then compare the outputs from 2 stages as well as the changes in h-indexes between 2 sets of self-citation inclusion and exclusion.
    DOI:  https://doi.org/10.1097/MD.0000000000031609
  15. Front Public Health. 2022 ;10 1047116
    Research trends and hotspots in the relationship between outdoor activities and myopia: A bibliometric analysis based on the web of science database from 2006 to 2021.
    Jingfeng Mu, Haoxi Zhong, Dan Zeng, Jingjie Fan, Mingjie Jiang, Meizhou Liu, Xinyi Shuai, Yanjie Chen, Shaochong Zhang.
      Objectives: This study aimed to explore the current status, hotspots, and emerging research trends regarding the relationship between outdoor activities and myopia.Methods: Publications on the relationship between outdoor activities and myopia from 2006 to 2021 were collected from the Web of Science Core Collection database. CiteSpace (version 6.1.R2) was used to performed a bibliometric analysis, and R software (version 4.1.0) was used to visualize the trends and hot map of publications.
    Results: A total of 640 publications were collected and analyzed in the present study. China was the major contributor (n = 204), followed by the United States of America (n = 181) and Australia (n = 137). The United States of America had the most extensive foreign cooperation (centrality = 0.25), followed by Australia (centrality = 0.20). The National University of Singapore contributed the largest number of publications (n = 48), followed by Sun Yat-Sen University (n = 41) and the Australian National University (n = 41). Among institutions, Cardiff University in the United Kingdom had the most extensive foreign cooperation (centrality = 0.12), followed by the National University of Singapore (centrality = 0.11). Saw S from Singapore had the largest number of publications (n = 39), followed by Morgan I from Australia (n = 27) and Jonas J from Germany (n = 23). Investigative ophthalmology & visual science is the most important journal to study the relationship between outdoor activities and myopia. "Global Prevalence of Myopia and High Myopia and Temporal Trends from 2000 through 2050" published by Holden BA was the most cited paper in this field with 177 citations. Co-occurrence and burst analyses of keywords showed that research trends and hotspots in this field focused mainly on "risk," "prevention" and "school".
    Conclusions: The influence of outdoor activities on myopia remains a concern. In the future, deeper cooperation between countries or institutions is required to explore the effects of outdoor activities on myopia. Outdoor activities for the prevention of myopia and reduction of the risk of myopia among school students may be the focus of future research.
    Keywords:  CiteSpace; bibliometrics; data visualization; myopia; outdoor activities
    DOI:  https://doi.org/10.3389/fpubh.2022.1047116
  16. Medicine (Baltimore). 2022 Nov 11. 101(45): e30996
    Trends and frontiers in natural products for arthritis, 2000-2021: A bibliometric analysis.
    Junying Pan, Haoyu Wang, Yinghua Chen.
      BACKGROUND: Arthritis has become one of the trouble diseases that upsets people. A growing number of studies have shown that natural products have great potential for the treatment of arthritis. However, few bibliometrics have been systematically studied in this area. This paper analyzes the literature data of natural products on the arthritis research, and the research hot spots and future research directions of the treatment of arthritis by natural products were explored.METHOD: Through CiteSpace, VOSviewer software and Bibliometricx under the R language environment, the article and review literatures on the treatment of arthritis with natural drugs in the Web of Science core collection database were analyzed by bibliometric analysis.
    RESULTS: On December 28, 2021, a total of 2102 records were retrieved, 81.69% publications were issued in 2012 to 2021, mainly in China-dominated Asian countries, with cooperation among countries. The analysis of the number of articles published by institutions shows that the number of articles published by China Academy of Chinese Medical Sciences is up to 82. Lu, Aiping and Smolen, JS are the authors with the highest citation frequency and co-citation frequency. Keywords analysis showed that the research of natural drugs mainly focused on gene expression, anti-inflammatory and other mechanisms and signaling pathways. With the progress of science and technology and the integration of multi-disciplines, the research on natural drugs for arthritis will be more in-depth and specific.
    CONCLUSION: In this study, literature metrology analysis was conducted on natural products in the treatment of arthritis, in order to grasp the background, trends and frontiers of the research, and predict possible research hotspots in the future. It is expected to provide some reference value and direction for future scholars in this field.
    DOI:  https://doi.org/10.1097/MD.0000000000030996
  17. Psychol Health Med. 2022 Nov 18. 1-20
    The top-100 cited articles on post-traumatic stress disorder: a historical bibliometric analysis.
    Mauro Vitor Mendlowicz, Márcio Gekker, Alexandre Xavier Gomes de Araújo, Letícia de Oliveira, Mirtes Garcia Pereira, William Berger, Mariana Pires da Luz, Liliane Maria Pereira Vilete, Carla Marques-Portella, Ivan Figueira, Taylor Reis da Silva Junior.
      This is a bibliometric analysis of the most-cited articles on post-traumatic stress disorder (PTSD) with the objective of identifying citation patterns for researchers, journals, centers, periods, topics, and nations. A search was conducted in Thomson Reuters' WoS Core Collection employing the expression TI = (posttraumatic stress disorder OR post-traumatic stress disorder OR PTSD). The 100 most-cited articles were downloaded, and the relevant data were extracted and analyzed. These studies had a total of 69,649 citations, ranging from a minimum of 360 to a maximum of 6029 citations, with an average of 696.49, a standard deviation of 720.92, mode of 369, and a median of 512. Eighty-eight percent of the most-cited articles on PTSD originated from the USA, with just six cities accounting for 52% of the publications and the Boston area alone responsible for almost one-fifth of the total output. The universities of Yale and Harvard headed the ranking of institutions with larger numbers of highly-cited articles. Female researchers represented 42.3% of all authors, 51% of the first authors, and 48% of the corresponding authors. The proportion of M.D. authors decreased significantly between the 1980-1999 (42%) and the 2000-2019 (27.2%) periods while that of Ph.D. authors increased from 44% to 57.4%. The most studied population was military veterans (28%). Female victims of sexual or physical violence, traumatized children, and adult survivors of childhood abuse were assessed in only 6-7% of the most-cited publications. Ten clinical trials evaluated psychological interventions but only three investigated pharmacotherapy. We concluded that influential research on PTSD remains centralized in the USA. A balanced gender representation in publications was found. There was a heavy reliance on combat veterans as the study population. Few highly-cited studies on the pharmacotherapy for PTSD were identified. Focused efforts are needed to address these challenges.
    Keywords:  PTSD; Post-traumatic stress disorder; bibliometric analysis; bibliometrics; researchers; sexism
    DOI:  https://doi.org/10.1080/13548506.2022.2147555
  18. Ann Med Surg (Lond). 2022 Dec;84 104823
    Bibliometric analysis of contributions to COVID-19 research in Malaysia.
    Temitope Folashade Aroyewun, Sefiu Olalekan Olaleye, Yusuff Adebayo Adebisi, Asma Perveen.
      Introduction: The advent of COVID-19 has led to an exponential rise in related publications to provide a knowledge driven approach to tame the tide of infection and impact in all spheres. This study gives an insight into COVID-19 research publication pattern in Malaysia using bibliometric analysis.Method: COVID-19 publications on Scopus database between January 1, 2020, and August 26, 2022, were extracted using predetermined search strings. Inclusion and exclusion criteria were set, and data was extracted from the database. Descriptive statistics was used to summarize our findings.
    Results: A total of 3,553 COVID-19 related papers were retrieved out of global count of 392,613 and 16,466 for Southeast Asia (SEA). This implies that 0.9% and 21.6% is contributed globally and SEA respectively. Indonesia, Malaysia and Singapore are the three top countries with highest research outputs in the region. This may be correlated to high GDP per capita, research and development, and research and development expenditure. Most of the publications are article/original research (n = 2832, 67%). Ministry of Higher education is the top funding sponsor and Universiti Malaya is the highest contributor and the most cited (n = 466, 4920 citations). The majority of publications are from physical sciences (30.3%), but medicine subcategory produced the highest number of papers (1,586). The top journal was International Journal of Environmental and Public Health (n = 96 publications). Most active collaborating country was the United Kingdom and most active author was from Monash University.
    Conclusion: Malaysian institutions have made profound contributions to COVID-19 research globally and in SEA. However, there is a need for continuous efforts to improve research outputs on the topic.
    Keywords:  Active collaborator; Bibliometric analysis; COVID-19 publications; Malaysia; Research outputs
    DOI:  https://doi.org/10.1016/j.amsu.2022.104823
  19. Front Public Health. 2022 ;10 1017817
    Dynamic structures and emerging trends in the management of major trauma: A bibliometric analysis of publications between 2012 and 2021.
    Zhe Du, Zhenzhou Wang, Fuzheng Guo, Tianbing Wang.
      Objective: Major trauma is currently a global public health issue with a massive impact on health at both the individual and population levels. However, there are limited bibliometric analyses on the management of major trauma. Thus, in this study we aimed to identify global research trends, dynamic structures, and scientific frontiers in the management of major trauma between 2012 and 2021.Methods: We searched the Web of Science Core Collection to access articles and reviews concerning the management of major traumas and conducted a bibliometric analysis using CiteSpace.
    Results: Overall, 2,585 studies were screened and published by 403 institutions from 110 countries/regions. The most productive country and institution in this field of research were the USA and Monash University, respectively. Rolf Lefering was the most prolific researcher and Holcomb JB had the most co-citations. Injury published the highest number of articles, and the Journal of Trauma was the most co-cited journal. A dual-map overlay of the literature showed that the articles of most publications were confined to the areas of medicine/medical/clinical and neurology/sports/ophthalmology. Document clustering indicated severe traumatic brain injury, traumatic coagulopathy, and resuscitative endovascular balloon occlusion as the recent hot topics. The most recent burst keywords were "trauma management," "neurocritical care," "injury severity," and "emergency medical services."
    Conclusion: The dynamic structures and emerging trends in the management of major trauma were extensively analyzed using CiteSpace, a visualization software. Based on the analysis, the following research hotspots emerged: management of severe traumatic brain injury and massive hemorrhage, neurocritical care, injury severity, and emergency medical service. Our findings provide pertinent information for future research and contribute toward policy making in this field.
    Keywords:  CiteSpace; bibliometric analysis; major trauma; management; visualization
    DOI:  https://doi.org/10.3389/fpubh.2022.1017817
  20. Front Cell Dev Biol. 2022 ;10 1043725
    A bibliometric analysis of PIN1 and cell death.
    Jia-Heng Zhang, Shi-Yu Ni, Ya-Ting Tan, Jia Luo, Shu-Chao Wang.
      Background: Regulation of cell death plays a key role in numerous diseases. As a proline isomerase, prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) is important for the regulation of signaling pathways. An in-depth understanding of how Pin1 participates in the process of cell death, which affects the occurrence and development of diseases, will aid in the discovery of new disease mechanisms and therapeutic methods. Thus, the purpose of our study was to discover the research trends and hotspots of Pin1 and cell death through bibliometric analyses and to provide insights for understanding the future development of basic research and treatment of diseases. Methods: Documents were extracted from the Web of Science Core Collection on 7 May 2022. We selected articles and reviews published in English from 2000 to 2021, and visual and statistical analyses of countries, institutions, authors, references and keywords were performed using VOSviewer 1.6.18 and CiteSpace 5.8. Results: A total of 395 articles and reviews were selected. Since 2001, the number of articles on Pin1 and cell death has increased annually. Publications come from 43 countries, with the US having the most publications and citations. We identified 510 authors, with Giannino Del Sal having the most articles and Paola Zacchi having the most co-citations. The Journal of Biological Chemistry is the most researched journal, and Nature and its subjournals are the most cited journals. Apoptosis, phosphorylation, and breast cancer were the three most common keywords. Conclusion: The number of documents showed an increasing trend from 2001 to 2014. Stagnant growth after 2014 may be related to the absence of new research hotspots. Cooperative links between core institutions need to be strengthened, and the institution with the highest citation count in recent years is Fujian Medical University in China. The role of Pin1 in cell death requires further research to discover new research hotspots. Before breakthroughs in molecular mechanism or signaling pathway research, future research will focus more on the treatment of diseases represented by Pin1 inhibitors.
    Keywords:  CiteSpace; Pin1; VOSviewer; apoptosis; autophagy; bibliometric analysis; cell death; necrosis
    DOI:  https://doi.org/10.3389/fcell.2022.1043725
  21. J Family Med Prim Care. 2022 Jul;11(7): 3967-3970
    A bibliometric review on the top 20 cited articles in the Jackson heart study.
    Mohammad Abrar Shareef, Abdulhadi A AlAmodi.
      Background: Cardiovascular diseases are higher in African American population, and in the past three decades, less decline in mortality was observed in African Americans compared with white Americans American health disparities resulted in establishing one of the largest single-site investigations to examine causes of cardiovascular diseases in African American population, namely the Jackson Heart Study (JHS).Methods: In January 2020, we used the jacksonheartstudy.org website to obtain the list of publications produced by the JHS from 1999 to 2018. The citation's frequency was obtained for 455 articles using the search engine "google.com". The top 20 cited articles were characterized based on the first author's name, the month and year of publication, and the journal's name and its impact factor.
    Results: The frequency of citations for the 20 most-cited articles in the Jackson heart study ranged from 282 to 5545. The average number of citations was 1045.60. The top 20 articles were represented in 8 different peer-reviewed journals.
    Conclusion: The top 20 cited articles in the JHS were in the genetics field and were all observational in type. Future direction of the JHS should be directed toward well established interventional studies.
    Keywords:  Cardiovascular diseases; Jackson heart study; citations
    DOI:  https://doi.org/10.4103/jfmpc.jfmpc_537_20
  22. Front Pharmacol. 2022 ;13 1035229
    Research trends and frontiers on antiphospholipid syndrome: A 10-year bibliometric analysis (2012-2021).
    Teng Wu, Wei Huang, Jiaping Qi, Yixuan Li, Yuan Zhang, Huan Jiang, Jing Wang, Ju Zhang, Zhaoyu Jiang, Lin Chen, Zhenhua Ying.
      Objectives: A growing body of studies related to antiphospholipid syndrome (APS) have been published in recent years. Nevertheless, there is a lack of visualized and systematic analysis in the literature on APS. Hence, this study sought to conduct a bibliometric analysis to identify research status and discover frontiers in the field. Methods: Articles and reviews concerning APS were acquired from the Web of Science Core Collection (WoSCC) database. CiteSpace, VOSviewer and a bibliometric online analysis platform were employed to conduct a visualization and knowledge-map analysis. Results: A total of 1,390 publications regarding APS were identified. Globally, Italy contributed the most publications. The University of Padua was the most productive institution. Lupus ranked first in both the most published and most co-cited journals. Savino Sciascia and Spiros Miyakis were the most prolific and most co-cited authors, respectively. "Vitamin K antagonists (VKA)" and "immunoglobulin A (IgA)" were current research foci. Burst analysis of keywords suggested that "neutrophil extracellular trap (NET)," "direct oral anticoagulant (DOAC)," "open label," "outcome," "hydroxychloroquine (HCQ)," and "arterial thrombosis (AT)" were significant future research frontiers. Conclusion: The scientific literature on APS has increased steadily in the past 10 years. The clinical studies on the treatment and mechanism research of APS are recognized as promising research hotspots in the domain of APS. The research status and trends of APS publications from the bibliometric perspective can provide a practical guide and important reference for subsequent studies by researchers and physicians in the domain.
    Keywords:  CiteSpace; VOSviewer; antiphospholipid syndrome; bibliometric; hotspots
    DOI:  https://doi.org/10.3389/fphar.2022.1035229
  23. Medicine (Baltimore). 2022 Nov 18. 101(46): e31859
    Bibliometric and visual analysis of mesenchymal stem cells in the treatment of osteoporosis based on CiteSpace software.
    Runfang Wang, Yueying Wang, Weiyi Zai, Ning Xu.
      BACKGROUND: The focus of research in the treatment of osteoporosis (OP) has evolved from promoting bone formation and inhibiting bone resorption to current stem cell therapy. Due to their multipotent differentiation properties, mesenchymal stem cells (MSCs) can repair degenerated bones through transplantation, and have become a new method for the treatment of OP.METHODS: Relevant literatures included in the Web of Science database core collection database from 2012 to 2021 were retrieved. CiteSpace software was used to analyze the cooperative relationship among authors, journals, institutions, and countries, and to analyze the co-citation situation of the literature. And performed co-occurrence analysis, cluster analysis and burst analysis of keywords, draw visual maps and analyzed the results.
    RESULTS: A total of 2100 papers were included, and the number of papers published from 2012 to 2021 was on the rise. A total of 484 authors were included, and 176 authors published more than 3 papers. The high-yield authors were mainly represented by YAN JIN and BO GAO. A total of 99 journals were included, and the journal with the most publications was J BONE MINER RES. A total of 787 institutions were included, and the institution with the largest number of publications was Shanghai Jiao Tong University. A total of 65 countries were included. The country with the largest number of publications was China, and the United States had the highest centrality. The co-citation analysis of the literature found 2 articles with high citation frequency and high centrality. The main research direction was the mechanism of MSCs in the treatment of osteoporosis. A total of 133 keywords were included, and the hot keywords were osteogenic differentiation, expression, proliferation, bone marrow, etc.
    CONCLUSIONS: The research hotspots in this field mainly focused on the mechanism of bone regeneration, proliferation and osteogenic differentiation of bone marrow MSCs, and the expression of osteogenic-related genes. The future research trends in this field are predicted to be the mechanism of action of microRNA and long non-coding RNA on MSCs and their relationship with OP, the mechanism of MSCs adipogenic and osteogenic differentiation, and tissue engineering scaffolds applications.
    DOI:  https://doi.org/10.1097/MD.0000000000031859
  24. Front Med (Lausanne). 2022 ;9 952487
    Trends in research related to menopausal hormone therapy from 2000 to 2021: A bibliometric analysis.
    Jing Li, Zhipeng Wei, Jingxi Wu, Kaili Min, Xiao Li, Yuan Yao, Yao Li, Ningning Zhang, Anya Shi, Jiani Han, Chengdong Qiao, Kehu Yang.
      We conducted the present bibliometric analysis to explore menopausal hormone therapy (MHT)-related research trends between 2000 and 2021. The Web of Science database was systematically searched from 2000 to 2021 to retrieve MHT-related publications. Visualization mapping and keyword cluster graphs were utilized to illustrate the research topics and hotpots. We included 11,616 MHT-related publications for this bibliometric analysis. The results showed that (1) MHT-related research had a very slow increase in the past 22 years, and the trend fluctuated. Sum of times cited and average citations per item had the same trend: a sharp decline from 2002 to 2003, and a rapid increase from 2003 to 2006, reaching the peak in 2006, then following a downward trend. The average H-index was 57, peaking in 2001; (2) the USA, the League of European Research Universities, and Dr. JoAann Manson from Harvard University contributed the most; (3) Menopause: The Journal of The North American Menopause Society had the most significant number of MHT-related publications; (4) the research hotpots primarily focused on MHT for treating menopausal symptoms and the impact of MHT on women's health. According to previous studies, MHT was the most effective treatment for managing vasomotor symptoms of menopause, but results from the clinical trials and observational studies regarding MHT adverse events remain inconsistent. Mechanisms are fundamental when clinical studies give conflicting results. Therefore, future studies should focus on adverse events and their mechanisms.
    Keywords:  adverse events; bibliometric analysis; menopausal hormone therapy; menopausal women; treatment
    DOI:  https://doi.org/10.3389/fmed.2022.952487
  25. Front Immunol. 2022 ;13 1045795
    Knowledge mapping of the links between the microbiota and allergic diseases: A bibliometric analysis (2002-2021).
    Hao Lv, Yunfei Wang, Ziang Gao, Peiqiang Liu, Danxue Qin, Qingquan Hua, Yu Xu.
      Background: In recent decades, dramatic changes in modern environmental exposures and lifestyles have resulted in a steep rise in the prevalence of allergic diseases such as asthma, allergic rhinitis, atopic dermatitis and food allergies. Evidence is mounting that the microbiota plays a crucial role in allergic disorder development and evolution. Therefore, a better understanding of allergic diseases within the context of the microbiota is urgently needed. This work aimed to comprehensively outline general characteristics, research hotspots, evolution routes, and emerging trends in this area.Methods: Relevant publications from January 2002 to December 2021 were obtained from the Web of Science Core Collection on 5 August 2022. Bibliometric and visual analyses were performed using CiteSpace; VOSviewer; an online bibliometric platform; and Microsoft Excel 2019.
    Results: In total, 2535 documents met the requirements. The annual number of publications has shown rapid growth in the last two decades. The USA, University of California System, and Isolauri E of the University of Turku were the most productive and influential country, institution, and author, respectively. The Journal of Allergy and Clinical Immunology was the most prolific and most cocited journal. High-frequency keywords included "gut microbiota", "asthma", "atopic dermatitis", "children", and "probiotics". Recent studies have focused on "atopic dermatitis", "skin", "asthma", and "probiotics", according to the cocitation analysis of references. Burst detection analysis of keywords showed that "community", "skin microbiome", "microbiome", "Staphylococcus aureus", and "chain fatty acid" were emerging research frontiers, which currently have ongoing bursts.
    Conclusion: In the last 20 years, studies of the microbiota in allergic diseases have been flourishing, and the themes have been increasing in depth. These findings provide valuable references on the current research hotspots and gaps and development trends in the link between the microbiota and allergic diseases.
    Keywords:  allergic diseases; bibliometric analysis; developing trends; microbiota; visual analysis
    DOI:  https://doi.org/10.3389/fimmu.2022.1045795
  26. Medicine (Baltimore). 2022 Nov 11. 101(45): e31033
    The use of radar plots with the Yk-index to identify which authors contributed the most to the journal of Medicine in 2020 and 2021: A bibliometric analysis.
    Yang Shao, Tsair-Wei Chien, Fong-Lin Jang.
      BACKGROUND: A consensus exists that the first author and corresponding author make the most contribution to the publication of an article. The Y-index has been proposed to assess the scientific achievements of authors, institutions, and countries/regions (AIC/R for short) based on the number of first-author publications (FPs) and corresponding-author publications (RPs). Nonetheless, the Y-index is defined in terms of count and radian (represented by j and h) instead of using the relative radius and angle degree to simplify understanding. In the literature, a method for drawing radar diagrams online with the Y-index is also lacking. This study was conducted to enhance the Y-index with an additional relative radius denoted by k and the angle degree represented by h* (named Yk-index), include easy-to-use features (e.g., copying and pasting) for the delivery of the online Radar-Yk, and identify which one of AIC/R contributed the most to a scientific journal.METHODS: From the Web of Science (WoS) database, we downloaded 9498 abstracts of articles published in the journal of Medicine (Baltimore) in 2020 and 2021. Three visual representations were used, including a Sankey diagram, a choropleth map, and a radar diagram, to identify the characteristics of contributions by AIC/R to Medicine (Baltimore) using the Yk-index (j, k, h*). A demonstration of Rada-Yk with easy-to-use features was given using the copy-and-paste technique.
    RESULTS: We found that Qiu Chen (China), Sichuan University (China), China, and South Korea (based on regions, e.g., provinces/metropolitan areas in China) were the most productive AIC/R, with their Yk equal to 27,715, 12415.1, and 2045, respectively; a total of 85.6% of the published articles in Medicine (Baltimore) came from the 3 countries (China, South Korea, and Japan); and this method of drawing the Radar-Yk online was provided and successfully demonstrated.
    CONCLUSION: A breakthrough was achieved by developing the online Radar-Yk to show the most contributions to Medicine (Baltimore). Visualization of Radar-Yk could be replicated for future academic research and applications on other topics in future bibliographical studies.
    DOI:  https://doi.org/10.1097/MD.0000000000031033
  27. Environ Sci Pollut Res Int. 2022 Nov 15.
    Contributions toward sustainable development: a bibliometric analysis of sustainability reporting research.
    Nana Adwoa Anokye Effah, Qinggang Wang, Godfred Matthew Yaw Owusu, Octavia Ama Serwaa Otchere, Bright Owusu.
      The study determines the development of the sustainability reporting domain using a dataset of publications extracted from the Web of Science (WoS) core database and visualized with CiteSpace. This paper employs a bibliometric approach to review extant studies to present and describe the publication patterns from 2004 to 2021. The top 3 contributing journals are the Journal of Cleaner Production, Sustainability, and Accounting, Auditing, and Accountability Journal, whereas the author network depicts a low collaboration among authors. Many authors have autonomously conducted their research, and the regional contributions to the research domain have been uneven. The paper accentuates the need to bridge the uneven institutional and regional contributions toward the sustainability reporting domain, so more light is shed on environmental sustainability across regions through firm and institutional levels. The results will trigger the need for future studies and actions needed to improve reporting quality through extensive social, environmental, and governance disclosures.
    Keywords:  Bibliometric analysis; CSR; Citations; SDGs; Sustainability reporting; Sustainable development
    DOI:  https://doi.org/10.1007/s11356-022-24010-8
  28. Front Med (Lausanne). 2022 ;9 968814
    Nutrition and sarcopenia: Current knowledge domain and emerging trends.
    Huanhuan Huang, Zhiyu Chen, Lijuan Chen, Songmei Cao, Dingqun Bai, Qian Xiao, Mingzhao Xiao, Qinghua Zhao.
      Objective: Non-pharmacological management like nutrient supplements has shown positive impacts on muscle mass and strength, which has burgeoned clinical and research interest internationally. The aim of this study was to analyze the current knowledge domain and emerging trends of nutrition-related research in sarcopenia and provide implications for future research and strategies to prevent or manage sarcopenia in the context of aging societies.Materials and methods: Nutrition- and sarcopenia-related research were obtained from the Web of Science Core Collection (WoSCC) database from its inception to April 1, 2022. Performance analysis, science mapping, and thematic clustering were performed by using the software VOSviewer and R package "bibliometrix." Bibliometric analysis (BA) guideline was applied in this study.
    Results: A total of 8,110 publications were extracted and only 7,510 (92.60%) were selected for final analysis. The production trend in nutrition and sarcopenia research was promising, and 1,357 journals, 107 countries, 6,668 institutions, and 31,289 authors were identified in this field till 2021. Stable cooperation networks have formed in the field, but they are mostly divided by region and research topics. Health and sarcopenia, metabolism and nutrition, nutrition and exercise, body compositions, and physical performance were the main search themes.
    Conclusions: This study provides health providers and scholars mapped out a comprehensive basic knowledge structure in the research in the field of nutrition and sarcopenia over the past 30 years. This study could help them quickly grasp research hotspots and choose future research projects.
    Keywords:  VOSviewer; bibliometric analysis; co-words; nutrition; sarcopenia
    DOI:  https://doi.org/10.3389/fmed.2022.968814
  29. Front Mol Neurosci. 2022 ;15 1023692
    Bibliometric analysis of research on gene expression in spinal cord injury.
    Siqiao Wang, Weijin Qian, Shaofeng Chen, Shuyuan Xian, Minghao Jin, Yifan Liu, Hao Zhang, Hengwei Qin, Xinkun Zhang, Jiwen Zhu, Xi Yue, Chaofeng Shi, Penghui Yan, Runzhi Huang, Zongqiang Huang.
      Background: Spinal cord injury (SCI) is a severe disease with motor and sensory function being destroyed, which leads to a poor prognosis and a serious financial burden. It is urgent to figure out the molecular and pathological mechanisms of SCI to develop feasible therapeutic strategies. This article aims to review documents focused on gene expression in SCI and summarize research hotspots and the development process in this field.Methods: Publications of SCI-related studies from 2000 to 2022 were retrieved from the Web of Science Core Collection database. Biblioshiny was used to evaluate the research performance, core authors, journals and contributed countries, together with trend topics, hotspots in the field, and keyword co-occurrence analysis. Visualized images were obtained to help comprehension.
    Results: Among 351 documents, it was found that the number of annual publications increased in general. The most productive country was China, followed by the United States with the highest influence and the most international cooperation. Plos One was the journal of the maximum publications, while Journal of Neuroscience was the most influential one. According to keyword co-occurrence and trend topics analysis, these articles mainly focused on molecular and pathological mechanisms as well as novel therapies for SCI. Neuropathic pain, axonal regeneration and messenger RNA are significant and promising research areas.
    Conclusion: As the first bibliometric study focused on gene expression in SCI, we demonstrated the evolution of the field and provided future research directions like mechanisms and treatments of SCI with great innovativeness and clinical value. Further studies are recommended to develop more viable therapeutic methods for SCI.
    Keywords:  gene expression; mechanism; microarray; sequencing; spinal cord injury
    DOI:  https://doi.org/10.3389/fnmol.2022.1023692
  30. Medicine (Baltimore). 2022 Nov 11. 101(45): e31133
    Knowledge mapping of copper-induced cell death: A bibliometric study from 2012 to 2022.
    Xue Ren, Ciming Pan, Zimeng Pan, Shanshan Zhao, Chen Wu, Wan Chen, Mengchen Liu, Xingyue Han, Hongying Kuang, Miao Qu.
      BACKGROUND: The recent article Copper induces cell death by targeting lipoylated TCA cycle proteins has attracted much attention. Although copper-induced cell death has only recently been formally proposed, it has been studied much earlier. This study aims to undertake a bibliometric analysis of the literature on copper-induced cell death to understand the development of copper-induced cell death better and identify potential new research directions.METHODS: With the help of Cite Space software, visual analysis is carried out on the annual number of published papers, countries/regions and institutions, journals co-citation, literature co-citation and reference burst, keywords co-occurrence, clustering, and burst.
    RESULTS: A search of 770 articles published in English over the last ten years showed a fluctuating trend of increasing numbers of articles. China had the highest number of articles (190% or 24.68%), followed by the USA and India. Inflammation, biological evaluation, nanoparticle, and cu(ii) have been popular research themes in the last 4 years. The keyword clusters are summarized in 8 categories, including exposure, complexe, er stress, cleavage, paraptosis, cancer, glutamate, reactive oxygen species (ROS), expression. The hot topics are mainly focused on the exploration of mechanisms and related diseases, including induced apoptosis, aggregation, autophagy, endoplasmic reticulum stress, induced oxidative stress, and inflammation. Parkinson's disease and cancer are 2 diseases that are closely related to copper-induced cell death.
    CONCLUSION: This study provides a visual analysis of copper-induced cell death trends and provides some hidden potentially useful information for future research directions.
    DOI:  https://doi.org/10.1097/MD.0000000000031133
  31. Acta Trop. 2022 Nov 10. pii: S0001-706X(22)00442-9. [Epub ahead of print] 106750
    A retrospective analysis of schistosomiasis related literature from 2011-2020: focusing on the next decade.
    Qingkai Xue, Yao Deng, Yiyun Liu, Yuyan Wang, Wenjun Hu, Yuzheng Huang, Kun Yang.
      BACKGROUND: Schistosomiasis, an ancient and neglected tropical disease, which poses a huge threat to over 200 million people globally. It is necessary to have a general summary of schistosomiasis research after the new roadmap 2021-2030 issued by WHO. This study analyzes the current status of schistosomiasis research from the perspective of the One Health concept by analyzing important research literature published from 2011 to 2020, while further highlighting research priorities, difficulties, and research directions in order to propose suggestions for tropical disease studies research.METHODS: Published literature related to schistosomiasis was searched from the Web of Science Core Collection (WoSCC) database. Focusing on a visual analysis of the main research literature in the field of schistosomiasis, CiteSpace software was used to conduct co-occurrence analysis with keywords, countries, institutions, and authors. Moreover, clustering and burst analyses of keywords and co-citation analysis of authors, publications, and journals were performed.
    RESULTS: A total of 6638 schistosomiasis-related articles were published from 2011 to 2020, all of which can be sourced from the WoSCC database. The publication of schistosomiasis research has remained stable over the past 10 years, and contains studies in the area of human epidemiology, animal surveillance and the environment. The top five high-frequency keywords included Schistosoma mansoni, schistosomiasis, infection, praziquantel, and Schistosoma japonicum. The keywords formed nine clusters, including praziquantel, epidemiology, Schistosoma japonicum, helminths, protein, diagnosis, schistosomiasis, response, and haematobium. In recent years, most research studies focused on the mechanism of liver fibrosis, eliminating schistosomiasis, controlling risk factors, and the relationship between schistosomiasis infection and host immunity. The most productive countries include the United States, China, and Brazil, and the most productive institutions are the University of Basel, the Swiss Tropical and Public Health Institute, and the University of São Paulo. Highly productive authors include Jürg Utzinger and Donald P. McManus. At the time of writing, the author with the highest co-citation frequency (993 times) was Peter Hotez, and the journal with the highest co-citation frequency (3,720 times) was PLoS Neglected Tropical Diseases. Human schistosomiasis, published by Colley et al. (2014), was the most frequently co-cited publication (494 times).
    CONCLUSIONS: This study provides a preliminary description of the current status of schistosomiasis research and an initial exploration of future research directions. The One Health concept was applied in the field of schistosomiasis control, as confirmed by this bibliometric analysis. Our study provides guidance for the development of research on schistosomiasis and other neglected tropical diseases.
    Keywords:  Bibliometrics; CiteSpace; One Health; Schistosomiasis; World Health Organization NTD roadmap
    DOI:  https://doi.org/10.1016/j.actatropica.2022.106750
  32. J Family Med Prim Care. 2022 Jul;11(7): 3613-3621
    Journal of family medicine and primary care- A five year bibliometric analysis from 2016 to 2020.
    Sumit Mohan, Jyoti Thakur, Chander Mohan, Sakshi Agarwal, Richa Tirkey.
      Aim: To conduct a five-year bibliometric analysis of the Journal of Family Medicine and Primary Care (J Family Med Prim Care) between 2016 and 2020.Setting and Design: This retrospective secondary data analysis was conducted in the Department of Conservative, Endodontics and Aesthetic Dentistry, Dental Institute, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand and Rohilkhand Medical College and Hospital, Bareilly, UP.
    Material and Methods: The data of publications including research articles, review and case reports excluding editorials and letters to the editor, commentaries and invited articles published in the J Family Med Prim Care between 2016 and 2020 were downloaded from the journal website and analysed in terms of the bibliometric parameters.
    Results: The results revealed that the journal gave equal weightage to all types of articles. The total number of articles published between 2016 and 2020 was 2,426 out of which 1,666 articles were published from India and the remaining from other parts of the world. In India, the state of Delhi had the maximum publications while speciality Preventive and Social Medicine (22.42%) and General Medicine (23.12%) had the maximum articles. Moreover, between 2016 and 2020, J Family Med Prim Care had 2,132 citations of published articles and had 65 publications in 2020 about the Corona Virus Disease (COVID-19) pandemic.
    Conclusion: The issue numbers per year for J Family Med Prim Care has gradually increased over time. The publication is open for all fields of medical, dental sciences and allied sciences.
    Keywords:  Articles; bibliometric analysis; journal; publication
    DOI:  https://doi.org/10.4103/jfmpc.jfmpc_2086_21
  33. J Family Med Prim Care. 2022 Jul;11(7): 3771-3776
    Health research in the state of Odisha, India: A decadal bibliometric analysis (2011-2020).
    Jaya S Kshatri, Parmeshwar Satpathy, Sumita Sharma, Trilochan Bhoi, Smruti P Mishra, Soumya S Sahoo.
      Background: Bibliometric analyses are an important tool for evaluating health research outputs in terms of their distribution, trends, contributors, focus, and funding sources. The transition from millennium to sustainable development goals has led to a gradual shift in the health policy, and possibly, research priorities of low-income settings in the Empowered Action Group (EAG) states lagging in socioeconomic and health parameters, and also ranking low on innovations and research. In this study, we depict the recent trends, quantity, type, focus, and sources of health-related research in the EAG state of Odisha, India.Methods: Peer-reviewed published original research articles related to human health published between 1 January, 2011 and 31 December, 2020 and where the study population was the residents of Odisha, or the study site was in Odisha, exclusively or partially, were analyzed. The publication characteristics were tabulated, including the title, journal name, open access, date of publication, number of authors, designation of the authors, number of institutes involved, and name of the institute of the first author. The details of the study setting, study site, ethical clearance, and funding source were also analyzed.
    Results: The study identified 2,285 articles from database searches and included 666 articles after screening for bibliometric analysis. Most of the manuscripts had between three and six authors (43.5%). Two institutes from the state, the Regional Medical Research Center (ICMR-RMRC) and Kalinga Institute of Industrial Technology (KIIT), together contributed to 22.4% of the published manuscripts. Nearly 45.9% of the studies were community-based while 45.3% were hospital-based. While most of the published work was on infectious diseases, the proportion came down with time. An overwhelming majority of the studies were observational and less than 10% were experimental in design.
    Conclusions: The analysis shows a substantial increase in the number of publications in this decade. Priority setting of healthcare problems, increased funding, and capacity-building can give a much-necessitated impetus to more quality- and evidence-based research for aiding policy implementation and improvement of the overall health.
    Keywords:  Bibliometric analysis; Odisha; health research; publication trends
    DOI:  https://doi.org/10.4103/jfmpc.jfmpc_2192_21
  34. Heliyon. 2022 Nov;8(11): e11354
    Global academic output on COVID-19 and Guillain-Barre Syndrome: A bibliometric analysis.
    Carlos Quispe-Vicuña, Miguel Cabanillas-Lazo, Maria Eugenia Guerrero, Franco Mauricio, John Barja-Ore, Frank Mayta-Tovalino.
      The purpose of this study was to bibliometrically analyze scientific publications on Guillain-Barré syndrome (GBS) related to COVID-19. A specialized search of the Scopus was used (December 2019 to February 2022). Collected publications were evaluated in Scival (Elsevier). The results were arranged in tables for presentation. We found 959 papers that were collected and the highest percentage of these belonged to the area of Neurology. Josef Finsterer was the author with the highest academic production, but Benedict Michael was the one with the highest impact worldwide. Although the Universidade Federal de São Paulo (Brazil) was the college with the highest scientific production, it was King's College London that reported the highest impact. Regarding the journals, the Journal of Neurology is the one with the highest worldwide production. In addition, an increase in first quartile publication and articles with national collaboration was reported. Scholarly output on COVID-19 and GBS have been increasing. Although national collaboration has the highest proportion of manuscripts, it is the international type that reported a greater impact, this would show a great interest on the part of researchers from all over the world regarding this topic.
    Keywords:  Bibliometrics; COVID-19; Guillain-Barre syndrome
    DOI:  https://doi.org/10.1016/j.heliyon.2022.e11354
  35. Innov High Educ. 2022 Nov 05. 1-17
    In Search of an Academic "Greatest Hits" Album: An Examination of Bibliometrics and Bibliometric Web Platforms.
    Christopher R Marsicano, Alexander R K Nichols.
      Despite the relative youth of bibliometric web platforms (Google Scholar was released in 2004), they play an increasingly significant role in the assessment of the impact of scholars and the research they produce. This scholarly essay provides a thorough review of the literature on bibliometric platforms, the extent to which they make available relevant manuscripts for inclusion in research, and their use for the assessment of scholarly work. We describe the metrics found on common bibliometric platforms, proposed metrics not commonly found in platforms, and how those metrics may differ based on scholar race and gender. We identify pitfalls of citation metrics present on bibliometric platforms. Finally, we identify areas for expansion of the research on bibliometric platforms and development of new metrics.
    Keywords:  Bibliometric platforms; Citation disparities; Google Scholar
    DOI:  https://doi.org/10.1007/s10755-022-09631-8
  36. Front Oncol. 2022 ;12 1025876
    Emerging trends and focus of giant cell tumor of bone research from 2001-2021: A visualization research.
    Ying-Song Han, Yi-Fan Yang, Gang Chen, Hai-Liang Yu, Zhi-Guo Zhang, Bin Zhou.
      Giant cell tumor of bone is a highly invasive benign tumor with a high postoperative recurrence rate.OBJECTIVE: This study aims to analyze the research hotspots and trends of global research on giant cell tumor of bone in the past 20 years, to provide a reference for relevant personnel in this field to carry out academic research.
    METHODS: The literature related to giant cell tumor of bone from 2001 to 2021 was retrieved from the Web of Science. The bibliometrics research method and VOS Viewer were used to extract and analyze the keywords of the journal authors' research institutions, and the research status and development direction in the recent 20 years were visualized.
    RESULTS: A total of 2063 articles were included. The number of global publications is increasing every year. The United States contributes the most to global research, with the most citations and the highest H-index. The journal Clinical Orthopaedics and Related Research published the most articles on this issue. "Denosumab" and "h3f3a" will get more attention and be the next popular hotspot in the future.
    CONCLUSION: The study of giant cell tumor of bone is a hot spot of continuous development and has an important contribution to human health.
    Keywords:  bibliometrics; giant cell tumor of bone; global trend; research focus; visualized study
    DOI:  https://doi.org/10.3389/fonc.2022.1025876
  37. J Egypt Public Health Assoc. 2022 Nov 17. 97(1): 26
    Cancer research activity in the Arab world: a 15-year bibliometric analysis.
    Marc Machaalani, Jad El Masri, Lemir Majed El Ayoubi, Bassam Matar.
      BACKGROUND: The Arab region comprises 22 countries located in the Middle East and North Africa, sharing cultural and linguistic ties. Arab countries have continued to lag in terms of biomedical research compared to other nations for several past decades. Cancer is a major public health concern, being the second leading cause of death globally. Given that high research activity on cancer reflects positively on screening programs, awareness, and clinical practice, this article aimed to examine the activity and trend of cancer research in the Arab world between 2005 and 2019.METHODS: Between 2005 and 2019, the number of cancer-related articles published by each Arab country, and regarding 27 different types, was assessed using the PubMed database. Numbers were normalized with respect to each country's average population and average Gross Domestic Product (GDP).
    RESULTS: Arab countries contributed to 1.52% of total cancer publications. The number of cancer publications has steadily grown since 2005, with the last 7 years alone witnessing 75.69% of the total Arab cancer-related publications. In terms of publications per million persons, Qatar ranked first (393.74 per million persons), while in terms of publications per national GDP, Egypt ranked first (464.27 per billion US dollars). Breast, liver, and colorectal cancers had the highest numbers of all Arab cancer-related publications, while testicular, vulvar, and gallbladder cancers had the least.
    CONCLUSIONS: This paper pools information and insight for scientists, clinicians, funders, and decision-makers on the actualities and developments of cancer research in the Arab world. Addressing the barriers facing cancer research remains a cornerstone in the plan to improve the Arab world's output and contribution to the field of oncology.
    Keywords:  Arab countries; Bibliometric analysis; Cancer; Research productivity
    DOI:  https://doi.org/10.1186/s42506-022-00120-6
  38. Front Endocrinol (Lausanne). 2022 ;13 1036426
    Systematic bibliometric and visualized analysis of research hotspots and trends on the application of artificial intelligence in diabetic retinopathy.
    Ruoyu Wang, Guangxi Zuo, Kunke Li, Wangting Li, Zhiqiang Xuan, Yongzhao Han, Weihua Yang.
      Background: Artificial intelligence (AI), which has been used to diagnose diabetic retinopathy (DR), may impact future medical and ophthalmic practices. Therefore, this study explored AI's general applications and research frontiers in the detection and gradation of DR.Methods: Citation data were obtained from the Web of Science Core Collection database (WoSCC) to assess the application of AI in diagnosing DR in the literature published from January 1, 2012, to June 30, 2022. These data were processed by CiteSpace 6.1.R3 software.
    Results: Overall, 858 publications from 77 countries and regions were examined, with the United States considered the leading country in this domain. The largest cluster labeled "automated detection" was employed in the generating stage from 2007 to 2014. The burst keywords from 2020 to 2022 were artificial intelligence and transfer learning.
    Conclusion: Initial research focused on the study of intelligent algorithms used to localize or recognize lesions on fundus images to assist in diagnosing DR. Presently, the focus of research has changed from upgrading the accuracy and efficiency of DR lesion detection and classification to research on DR diagnostic systems. However, further studies on DR and computer engineering are required.
    Keywords:  CiteSpace; artificial intelligence; bibliometric; diabetic retinopathy; systematic analysis
    DOI:  https://doi.org/10.3389/fendo.2022.1036426
  39. Environ Sci Pollut Res Int. 2022 Nov 19.
    Knowledge domain and hotspot trends in coal and gas outburst: a scientometric review based on CiteSpace analysis.
    Chao Xu, Tong Yang, Kai Wang, Lin Guo, Xiaomin Li.
      Coal and gas outburst is one of the main dynamic disasters in coal mine production. In order to deeply understand the overall research progress in the field of coal and gas outburst, the Web of Science (WOS) database is used as the sample source, and the bibliometric analysis of the literature in the field of coal and gas outburst from 2000 to 2021 is carried out by CiteSpace software. The knowledge maps of the publication quantity, country, institution, and keyword cluster are drawn. The results show that the time distribution has gone through three stages of germination period, development period, and growth period. In terms of the cooperation network, China, Australia, and the USA are the main core research countries, while China University of Mining and Technology, Chongqing University, and Henan Polytechnic University are the main core research institutions, and the main core journals are IGCG, IGRMM, and Fuel. By drawing the knowledge map of keywords timeline, the evolution law of keywords in the field of coal and gas outburst with time is obtained. Taking keywords as the object, cluster labels with gas outburst, gas extraction, gas control, and pore structure as the core are presented. On this basis, from a new perspective, this paper outlines the "scientific research landscape map" in the field of coal and gas outburst, in order to provide a scientific reference for coal and gas outburst research.
    Keywords:  CiteSpace; Coal and gas outburst; Keyword cluster; Knowledge map
    DOI:  https://doi.org/10.1007/s11356-022-23879-9
  40. Front Oncol. 2022 ;12 981406
    Trends in metabolic signaling pathways of tumor drug resistance: A scientometric analysis.
    Ruiqi Jiang, Mingnan Cao, Shenghui Mei, Shanshan Guo, Wei Zhang, Nan Ji, Zhigang Zhao.
      Background: Cancer chemotherapy resistance is one of the most critical obstacles in cancer therapy. Since Warburg O first observed alterations in cancer metabolism in the 1950s, people gradually found tumor metabolism pathways play a fundamental role in regulating the response to chemotherapeutic drugs, and the attempts of targeting tumor energetics have shown promising preclinical outcomes in recent years. This study aimed to summarize the knowledge structure and identify emerging trends and potential hotspots in metabolic signaling pathways of tumor drug resistance research.Methods: Publications related to metabolic signaling pathways of tumor drug resistance published from 1992 to 2022 were retrieved from the Web of Science Core Collection database. The document type was set to articles or reviews with language restriction to English. Two different scientometric software including Citespace and VOS viewer were used to conduct this scientometric analysis.
    Results: A total of 2,537 publications including 1,704 articles and 833 reviews were retrieved in the final analysis. The USA made the most contributions to this field. The leading institution was the University of Texas MD Anderson Cancer Center. Avan A was the most productive author, and Hanahan D was the key researcher with the most co-citations, but there is no leader in this field yet. Cancers was the most influential academic journal, and Oncology was the most popular research field. Based on keywords occurrence analysis, these selected keywords could be roughly divided into five main topics: cluster 1 (study of cancer cell apoptosis pathway); cluster 2 (study of resistance mechanisms of different cancer types); cluster 3 (study of cancer stem cells); cluster 4 (study of tumor oxidative stress and inflammation signaling pathways); and cluster 5 (study of autophagy). The keywords burst detection identified several keywords as new research hotspots, including "tumor microenvironment," "invasion," and "target".
    Conclusion: Tumor metabolic reprogramming of drug resistance research is advancing rapidly. This study serves as a starting point, providing a thorough overview, the development landscape, and future opportunities in this field.
    Keywords:  drug resistance; metabolism; scientometrics; signaling pathways; tumor
    DOI:  https://doi.org/10.3389/fonc.2022.981406
  41. Health Info Libr J. 2022 Nov 13.
    Bibliometric analysis of COVID-19 publications shows the importance of telemedicine and equitable access to the internet during the pandemic and beyond.
    Mahnaz Samadeik, Peivand Bastani, Farhad Fatehi.
      BACKGROUND: Pandemics highlight the increasing role of information and communications technology for improving access to health care. This study aimed to present a bibliometric analysis of the concept of digital divide reported in the published articles concerning the coronavirus disease 2019 (COVID-19) pandemic.METHODS: To conduct this bibliometric analysis of research topics and trends, we used VOSviewer software. We developed a search strategy to retrieve peer-reviewed publications related to 'digital divide in the COVID-19 era' from the Scopus database.
    RESULTS: In total, 241 publications on the topic of digital divide and COVID-19 were retrieved from Scopus database between 2020 and 2021. The analysis of keywords co-occurrence of research topics revealed four main clusters including: 'telemedicine', 'Internet access and Internet use', 'e-learning' and 'epidemiology'. Seven characteristic categories were examined in these research topics, including: sociodemographic, economic, social, cultural, personal, material and motivational.
    CONCLUSION: 'Telemedicine' and 'Internet access and Internet use' as the largest clusters are connected to topics addressing inequalities in online health care access. Thus, policymakers should develop or modify policies in more egalitarian Internet access for all community members not only during a pandemic like the COVID-19 but also at regular times.
    Keywords:  digital divide; health literacy; information literacy; information need; internet access; pandemic; telemedicine
    DOI:  https://doi.org/10.1111/hir.12465
  42. Pain Res Manag. 2022 ;2022 8090209
    Dynamics of Acute Postsurgical Pain over the Last Decade: A Bibliometric Analysis.
    Zhimin Tan, Yanjie Dong, Qian Li.
      Objective: Minimizing acute postsurgical pain (APSP) remains a challenge, despite extensive research about it. This study comprehensively analyzed the literature on APSP to assess how the field has developed and where it may go in the future.Methods: Studies on APSP indexed in the Web of Science Core Collection and published from 2012 to 2021 were assessed for eligibility. Data from included studies were analyzed using CiteSpace, Python, and Microsoft.
    Results: Analysis of 5,236 publications on APSP showed that the number of articles per year has increased linearly. The United States leads other countries in terms of the number and centrality of publications. Cocitation analysis suggests that the field focused earlier on the incidence and risk factors of APSP, shifting later to a focus on the reduction and management of adverse outcomes due to APSP. The top-ranked keyword cluster during the study period was "short-term outcomes" (#0), followed by "risk factors" (#1). The strongest burst occurred for the keyword "combination," followed by "multimodal analgesia." The most recent burst occurred for the keywords "regional analgesia," "opioid use," "erector spinae plane block," and "infiltration."
    Conclusions: Hotspots in APSP research since 2012 have been incidence, risk factors, and control of negative outcomes. Future research is likely to concentrate on the use of opioids and technological innovations in regional anesthesia. Our findings may help APSP researchers and clinicians understand their field, optimize clinical practice, and plan future research.
    DOI:  https://doi.org/10.1155/2022/8090209
  43. J Environ Sci (China). 2023 Mar;pii: S1001-0742(22)00157-7. [Epub ahead of print]125 774-785
    Hotspots and trends of biological water treatment based on bibliometric review and patents analysis.
    Lili Jin, Xiangzhou Sun, Hongqiang Ren, Hui Huang.
      In order to reveal the hotspots and trends of biological water treatment from the perspectives of scientific and technological innovation, both of the bibliometric review and patents analysis were performed in this study. The Web of Science Core Collection database and Derwent Innovation Index database recorded 30023 SCI papers and 50326 patents, respectively were analyzed via information visualization technology. The results showed that China ranked the first in both papers and patents, while the United States and Japan had advantages in papers and patents, respectively. It was concluded through literature metrology analysis that microbial population characteristics, biodegradation mechanism, toxicity analysis, nitrogen and phosphorus removal and biological treatment of micro-polluted wastewater were the research hotspots of SCI papers. Activated sludge process and anaerobic-aerobic combined process were the two mainstream technologies on the basis of patent technology classification analysis. Technology evolution path of biological water treatment was also elucidated in three stages based on the citation network analysis. Furthermore, the future directions including research on the law of interaction and regulation of biological phases and pollutants and the technology innovations towards the targeted biotransformation or selective biodegradation of pollutants and resource reuse of wastewater were prospected.
    Keywords:  Bibliometric review; Biological water treatment; Patent analysis; Technology evolution path
    DOI:  https://doi.org/10.1016/j.jes.2022.03.037
  44. Int J Legal Med. 2022 Nov 14.
    From Deutsche Zeitschrift to International Journal of Legal Medicine-100 years of legal medicine through the lens of journal articles : Part 2: Deutsche Zeitschrift für die gesamte gerichtliche Medizin from 1948 to 1969.
    Ingo Wirth, Tony Fracasso, Heidi Pfeiffer, Andreas Schmeling.
      The interruption of the publication of the Deutsche Zeitschrift für die gesamte gerichtliche Medizin due to the war ended with volume 39 for the years 1948/1949. Until volume 66/1969, the journal appeared unchanged under the historical title. The 912 publications contained in the 28 volumes of these two decades cover topics from the main fields of forensic medicine, but also from related and unrelated disciplines. The topic-specific analysis of the publications shows a shift of the research focus in the German institutes since the post-war period. This is most evident in the decline in the number of publications from the fields of scientific and technical criminalistics as well as forensic psychiatry and psychology. An opposite trend with a significant increase in scientific papers was observed in alcohology, forensic genetics and traffic medicine. While the evaluated publications on most topics contain new findings that are still valid today, the use of blood group characteristics for forensic purposes came to an end as a result of the introduction of DNA analysis.
    Keywords:  Academic articles; History of legal medicine; Official publications
    DOI:  https://doi.org/10.1007/s00414-022-02912-z
  45. Prehosp Disaster Med. 2022 Nov 14. 1-7
    Malaysian Disaster Medicine Research: A Bibliographic Study of Publication Trends.
    Mohd Syafwan Bin Adnan, Alexander Hart, Attila J Hertelendy, Derrick Tin, Sally-Mae Abelanes, Fadi Issa, Gregory R Ciottone.
      INTRODUCTION: Despite the increasing risks and complexity of disasters, education for Malaysian health care providers in this domain is limited. This study aims to assess scholarly publications by Malaysian scholars on Disaster Medicine (DM)-related topics.METHODOLOGY: An electronic search of five selected journals from 1991 through 2021 utilizing multiple keywords relevant to DM was conducted for review and analysis.
    RESULTS: A total of 154 articles were included for analysis. The mean number of publications per year from 1991 through 2021 was 5.1 publications. Short reports were the most common research type (53.2%), followed by original research (32.4%) and case reports (12.3%). Mean citations among the included articles were 12.4 citations. Most author collaborations were within the same agency or institution, and there was no correlation between the type of collaboration and the number of citations (P = .942). While a few clusters of scholars could build a strong network across institutions, most research currently conducted in DM was within small, isolated clusters.
    CONCLUSION: Disaster Medicine in Malaysia is a growing medical subspecialty with a significant recent surge in research activity, likely due to the SARS-CoV-2/coronavirus disease 2019 (COVID-19) global pandemic. Since most publications in DM have been on infectious diseases, the need to expand DM-related research on other topics is essential.
    Keywords:  Malaysia; disaster; disaster education; disaster medicine; disaster research; disaster training; emergency medicine; prehospital care
    DOI:  https://doi.org/10.1017/S1049023X22002187
  46. Front Public Health. 2022 ;10 1063615
    Corrigendum: Global tendency and frontiers of research on myopia from 1900 to 2020: A bibliometrics analysis.
    Mengyuan Shan, Yi Dong, Jingyi Chen, Qing Su, Yan Wang.
      [This corrects the article DOI: 10.3389/fpubh.2022.846601.].
    Keywords:  CitNetExplorer; bibliometric analysis; global trends; myopia; myopia control; public health; refractive surgery
    DOI:  https://doi.org/10.3389/fpubh.2022.1063615
  47. Laryngoscope. 2022 Nov 16.
    Gender and Ethnic Diversity in Academic Facial Plastic Surgery.
    David W Chou, Eleanor Layfield, Karthik Prasad, Charles Shih, Kathleyn Brandstetter.
      OBJECTIVE: Characterize academic facial plastic surgeons by demographics, time in practice, academic productivity, and faculty position.STUDY TYPE: Cross-sectional study.
    METHODS: Facial plastic surgery faculty in US otolaryngology residencies with a title of assistant professor, associate professor, or professor were identified. Demographics and academic data were obtained from public profiles and Scopus.
    RESULTS: One hundred sixty-eight surgeons were identified. Females comprised 25.6%. Most surgeons were White (69.6%), followed by Asian (25%), Hispanic (3.6%), and Black (1.8%). Mean h-index was similar between sexes when controlling for years in practice (1.13 vs. 1.14, p = 0.575). Female representation was greater among early-career surgeons (41%) than among mid- or late-career surgeons (24% and 13%, respectively) (p = 0.006). The correlation of years in practice with academic title was similar between sexes. There was no difference in h-index (p = 0.384) or distribution of academic positions (p = 0.658) between White and non-White surgeons. There was no statistical difference in full professorship (p = 1.0) or research productivity (p = 0.974) between late-career White and non-White academic facial plastic surgeons. There was no statistical difference in promotion from assistant professorship (p = 0.506) or research productivity (p = 0.857) between White and non-White surgeons in practice for over 5 years.
    CONCLUSION: Female representation in academic facial plastic surgery is low, though greater gender parity among younger surgeons suggests an improving trend. Hispanic and Black surgeons remain significantly underrepresented in the field. Although increased diversity is needed in academic facial plastic surgery, established minority surgeons have experienced similar research productivity and advancement through academic ranks as their majority counterparts.
    LEVEL OF EVIDENCE: N/A Laryngoscope, 2022.
    Keywords:  diversity; ethnicity; facial plastic surgery; gender; race
    DOI:  https://doi.org/10.1002/lary.30478
  48. Proc Natl Acad Sci U S A. 2022 Nov 22. 119(47): e2118046119
    Is novel research worth doing? Evidence from peer review at 49 journals.
    Misha Teplitskiy, Hao Peng, Andrea Blasco, Karim R Lakhani.
      There are long-standing concerns that peer review, which is foundational to scientific institutions like journals and funding agencies, favors conservative ideas over novel ones. We investigate the association between novelty and the acceptance of manuscripts submitted to a large sample of scientific journals. The data cover 20,538 manuscripts submitted between 2013 and 2018 to the journals Cell and Cell Reports and 6,785 manuscripts submitted in 2018 to 47 journals published by the Institute of Physics Publishing. Following previous work that found that a balance of novel and conventional ideas predicts citation impact, we measure the novelty and conventionality of manuscripts by the atypicality of combinations of journals in their reference lists, taking the 90th percentile most atypical combination as "novelty" and the 50th percentile as "conventionality." We find that higher novelty is consistently associated with higher acceptance; submissions in the top novelty quintile are 6.5 percentage points more likely than bottom quintile ones to get accepted. Higher conventionality is also associated with acceptance (+16.3% top-bottom quintile difference). Disagreement among peer reviewers was not systematically related to submission novelty or conventionality, and editors select strongly for novelty even conditional on reviewers' recommendations (+7.0% top-bottom quintile difference). Manuscripts exhibiting higher novelty were more highly cited. Overall, the findings suggest that journal peer review favors novel research that is well situated in the existing literature, incentivizing exploration in science and challenging the view that peer review is inherently antinovelty.
    Keywords:  bias; novelty; peer review; publishing
    DOI:  https://doi.org/10.1073/pnas.2118046119
  49. Transl Cancer Res. 2022 Oct;11(10): 3440-3442
    Bibliometric analysis of an important diagnostic technique for the treatment of breast cancer.
    Ramon Handerson Gomes Teles, Camila Tamy Hiroki, Vanessa Morais Freitas.
      
    DOI:  https://doi.org/10.21037/tcr-22-2120
  50. Tuberc Res Treat. 2022 ;2022 8039046
    Topic Analysis and Mapping of Tuberculosis Research Using Text Mining and Co-Word Analysis.
    Meisam Dastani, Alireza Mohammadzadeh, Jalal Mardaneh, Reza Ahmadi.
      Tuberculosis is still one of the most severe progressive diseases; it severely limits the social and economic development of many countries. In the present study, the topic trend of scientific publications on tuberculosis has been examined using text mining techniques and co-word analysis with an analytical approach. The statistical population of the study is all global publications related to tuberculosis. In order to extract the data, the Scopus citation database was used for the period 1900 to 2022. The main keywords for the search strategy were chosen through consultation with thematic specialists and using MESH. Python programming language and VOSviewer software were applied to analyze data. The results showed four main topics as follows: "Clinical symptoms" (41.8%), "Diagnosis and treatment" (28.1%), "Bacterial structure, pathogenicity and genetics" (22.3%), and "Prevention" (7.84%). The results of this study can be helpful in the decision of this organization and knowledge of the process of studies on tuberculosis and investment and development of programs and guidelines against this disease.
    DOI:  https://doi.org/10.1155/2022/8039046
  51. Int J Pharm. 2022 Nov 12. pii: S0378-5173(22)00940-1. [Epub ahead of print]629 122385
    Analyzing and mapping the research status, hotspots, and frontiers of biological wound dressings: An in-depth data-driven assessment.
    Shenghai Shen, Langrun Deng, Yiheng Du, Jingjing Gao, Chuanhao Zhang, Yueduo Wang, Zhewen Shen, Yixuan Li, Xiaowen Chen, Hao Chen.
      Wound dressings can be applied over the wound sites to provide long-lasting wound management and improve wound healing. Biological wound dressings are superior to synthetic materials due to biodegradability and biocompatibility. These biomaterials have demonstrated huge potential in the field of wound dressings. Applying bibliometric analysis combined with results-based descriptions to characterize the research status, hotspots, and cutting-edge topics, this study is the first in-depth qualitative, quantitative, data-driven overview of biological wound dressings research in recent decades. Filtered data were used to construct co-citation, heatmaps, bi-clustering, strategy maps, and other analyses and visualization. The results show that research on biological wound dressings has progressed considerably in the last 5 years with extensive global collaboration. A clear knowledge base has been developed. Chitosan hydrogels, bacterial cellulose, active agents (silver nanoparticles, growth factors, curcumin, etc.), and electrospinning fibers stand out as research hotspots. The research frontiers include novel starting materials, precise and controlled release systems, and clinical and regenerative medicine applications. We interpreted an overview of the excavated topics and expected the findings here to provide a guide and inspire innovations for developing the next generation wound dressings.
    Keywords:  Antibacterial; Biomaterials; Drug delivery; Regenerative medicine; Wound healing
    DOI:  https://doi.org/10.1016/j.ijpharm.2022.122385
  52. Perspect Psychol Sci. 2022 Nov 14. 17456916221117159
    Contextualizing Gender Disparity in Editorship in Psychological Science.
    Zhicheng Lin, Ningxi Li.
      Discourse on gender diversity tends to overlook differences across levels of hierarchy (e.g., students, faculty, and editors) and critical dimensions (e.g., subdisciplines and geographical locations). Further ignored is its intersection with global diversity-representation from different countries. Here we document and contextualize gender disparity from perspectives of equal versus expected representation in journal editorship, by analyzing 68 top psychology journals in 10 subdisciplines. First, relative to ratios as students and faculty, women are underrepresented as editorial-board members (41%) and-unlike previous results based on one subfield-as editors-in-chief (34%) as well. Second, female ratios in editorship vary substantially across subdisciplines, genres of scholarship (higher in empirical and review journals than in method journals), continents/countries/regions (e.g., higher in North America than in Europe), and journal countries of origin (e.g., higher in American journals than in European journals). Third, under female (vs. male) editors-in-chief, women are much better represented as editorial-board members (47% vs. 36%), but the geographical diversity of editorial-board members and authorship decreases. These results reveal new local and broad contexts of gender diversity in editorship in psychology, with policy implications. Our approach also offers a methodological guideline for similar disparity research in other fields.
    Keywords:  editorship; gender diversity; global diversity; policy; psychology
    DOI:  https://doi.org/10.1177/17456916221117159
  53. J Coll Physicians Surg Pak. 2022 Nov;32(11): 1379-1380
    Beyond the Citation Counts: An Insight into Altmetrics.
    Muhammed Mubarak, Shabana Seemee.
      Null.
    DOI:  https://doi.org/10.29271/jcpsp.2022.11.1379
  54. Int J Biol Macromol. 2022 Nov 14. pii: S0141-8130(22)02689-7. [Epub ahead of print]
    Cassava starch films for food packaging: Trends over the last decade and future research.
    Julia Rabelo Vaz Matheus, Patrícia Marques de Farias, Juliana Martins Satoriva, Cristiano José de Andrade, Ana Elizabeth Cavalcante Fai.
      Cassava starch is one of the most available and cost-effective biopolymers. This work aimed to apply a bibliometric methodology to identify the most impactful scientific data on cassava starch and its residues for food packaging in the last ten years. As a result, an increasing interest in this subject has been observed, mainly in the past five years. Among the 85 selected scientific publications, Brazil and China have been leading the research on starch-based films, accounting for 39 % of the total. The International Journal of Biological Macromolecules was the main scientific source of information. Besides cassava starch, 41.18 % of these studies added other biopolymers, 5.88 % added synthetic polymers, and 4.71 % added a combination of both. Studies analyzed suggested that different modifications in starch can improve films' mechanical and barrier properties. In addition, 52.94 % of articles evaluated the film's bioactivity. Still, only 37.65 % assessed the performance of those films as food packaging, suggesting that more studies should be conducted on assessing the potential of these alternative packages. Future research should consider scale-up methods for film production, including cost analysis, assessment life cycle, and the impact on the safety and quality of a broader range of foods.
    Keywords:  Agro-industrial waste; Biodegradable film; Biopolymers
    DOI:  https://doi.org/10.1016/j.ijbiomac.2022.11.129
  55. Probl Sotsialnoi Gig Zdravookhranenniiai Istor Med. 2022 Dec 15. 30(s1): 1121-1126
    [PUBLICATION LANDSCAPE OF THE MOSCOW MEDICINE SCIENCE].
    O A Stepanova, E A Chernova, K Y Tarkhov.
      The paper presents the results of a scientometric analytical research on the study of the publication landscape formed by research institutes and scientific-practical centers subordinate to the Moscow Healthcare Department. The study was conducted using the analytical platform SciVal, the data source for which is the database Scopus, the time period was 5 years - from 2017 to 2021. The results obtained in the course of the study indicate a steady growth and positive dynamics of changes in the selected scientometric indicators, as well as a significant contribution of Moscow research institutes and scientific-practical centers to the publication flow of the Moscow Healthcare Department. For the publishing landscape of Moscow medical science, there is a wide variety of subject areas in which its publications are distributed, a significant part of which belongs to highly relevant topic clusters.
    Keywords:  Moscow Healthcare Department; Moscow research institutes and scientific-practical centers; SciVal; collaboration; publication activity; ranking; scientometrics; subject area
    DOI:  https://doi.org/10.32687/0869-866X-2022-30-s1-1121-1126
  56. Clin Psychol Eur. 2022 Jun;4(2): e7921
    Selected Trends in Psychotherapy Research: An Index Analysis of RCTs.
    Winfried Rief, Melina Kopp, Roya Awarzamani, Cornelia Weise.
      Background: We wanted to analyze trends in psychotherapy research during the last decade. We used published randomized clinical trials (RCTs) that are cited in Web of Science (WoS) as an index for these activities.Method: We searched for RCTs published between the years 2010 and 2019. Search criteria included cognitive-behavioral treatments (CBT), e-mental health, Acceptance and Commitment Therapy (ACT), psychodynamic treatments, interpersonal therapy (IPT), schema therapy, systemic therapy, mindfulness treatments, and emotion-focused therapy (EFT). The numbers of publications for each treatment approach were accumulated for 5-year blocks (2010 to 2014; 2015 to 2019).
    Results: The search revealed 4,523 hits for the selected treatment options, of which 1,605 were finally included in the analysis. There was a continuous increase in published RCTs, with 68% more trials during the second five-year block. CBT (68%) and eHealth interventions (18%) show an increase in the number of studies, but there were no significant changes in its percentage in relation to all published RCTs. The next frequent treatments were ACT (4%), psychodynamic treatments (2%), IPT (2%), and mindfulness interventions (2%). We found a significant increase of the percentage of mindfulness (p = .008) and a significant decrease of the percentage of psychodynamic treatments (p = .02). Systemic (1.1%), emotion-focused (0.7%) and schema therapy (0.6%) represented smaller parts of published RCTs.
    Conclusion: A continuous increase of published RCTs underlines an active field of research on psychological interventions. Third wave treatments such as mindfulness increased their representation in research, while the part of psychodynamic treatments decreased.
    Keywords:  ACT; CBT; eHealth; mental health care; mindfulness; psychodynamic treatments; psychotherapy research; randomized clinical trials RCT; schema therapy; systemic therapy
    DOI:  https://doi.org/10.32872/cpe.7921
  57. Arch Public Health. 2022 Nov 17. 80(1): 236
    Correction: Trends and focuses of hantavirus researches: a global bibliometric analysis and visualization from 1980 to 2020.
    Xiao Wei, Xinlou Li, Shuxuan Song, Xiaohui Wen, Tiezhi Jin, Chenxi Zhao, Xubin Wu, Kun Liu, Zhongjun Shao.
      
    DOI:  https://doi.org/10.1186/s13690-022-00989-x
  58. Mar Environ Res. 2022 Oct 23. pii: S0141-1136(22)00226-4. [Epub ahead of print]183 105781
    A decade of population genetics studies of scleractinian corals: A systematic review.
    Viridiana Alvarado-Cerón, Aarón Israel Muñiz-Castillo, María Geovana León-Pech, Carlos Prada, Jesús Ernesto Arias-González.
      Coral reefs are the most diverse marine ecosystems. However, coral cover has decreased worldwide due to natural disturbances, climate change, and local anthropogenic drivers. In recent decades, various genetic methods and molecular markers have been developed to assess genetic diversity, structure, and connectivity in different coral species to determine the vulnerability of their populations. This review aims to identify population genetic studies of scleractinian corals in the last decade (2010-2020), and the techniques and molecular markers used. Bibliometric analysis was conducted to identify journals and authors working in this field. We then calculated the number of genetic studies by species and ecoregion based on data obtained from 178 studies found in Scopus and Web of Science. Coral Reefs and Molecular Ecology were the main journals published population genetics studies, and microsatellites are the most widely used molecular markers. The Caribbean, Australian Barrier Reef, and South Kuroshio in Japan are among the ecoregions with the most population genetics data. In contrast, we found limited information about the Coral Triangle, a region with the highest biodiversity and key to coral reef conservation. Notably, only 117 (out of 1500 described) scleractinian coral species have genetic studies. This review emphasizes which coral species have been studied and highlights remaining gaps and locations where such data is critical for coral conservation.
    Keywords:  Bibliometric analysis; Life-history; Marine ecoregion; Molecular markers; Population genetics; Scleractinian corals
    DOI:  https://doi.org/10.1016/j.marenvres.2022.105781
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