bims-evares Biomed News
on Evaluation of research
Issue of 2023‒01‒01
forty-four papers selected by
Thomas Krichel
Open Library Society


  1. Eur J Med Chem. 2022 Dec 21. pii: S0223-5234(22)00943-6. [Epub ahead of print]247 115041
      European Journal of Medicinal Chemistry (EJMC) has been around for a long time and has gained broad interest from the various individuals working in the field. However, there is no bibliometric analysis on the publications of EJMC to thoroughly assess the scientific output and current status systematically. Therefore, the study was conducted to analyze the various publications of EJMC from 1987 to 2022 to improve their quality. A total of 13,386 papers were retrieved, with the number of publications increasing yearly. Based on the multiple indicators of bibliometrics, the highest impact countries, institutions, authors and representative literature were identified, and visualization networks were constructed using VOSviewer. Keyword co-occurrence analysis reveals a gradual shift from phenotypic drug discovery to target-based drug discovery in the EJMC theme change. Moreover, further discussion of the keyword clustering results is provided to support researchers in defining the scope of their research topics and planning their research directions. At this stage, there is a greater focus on developing antitumor and oxidative stress-related drugs than on the earlier anti-infective activities. In future studies, the main research directions are tumor multidrug resistance, oxidative stress, and dual inhibitors.
    Keywords:  Bibliometric analysis; Citation analysis; Co-citation network; Research trends; VOSviewer
    DOI:  https://doi.org/10.1016/j.ejmech.2022.115041
  2. Front Med (Lausanne). 2022 ;9 944444
      Background: Bibliometric analysis was designed to investigate a systematic understanding of developments in exercise and osteoporosis research over the past 20 years.Methods: Relevant publications from the Web of Science Core Collection were downloaded on April 26, 2022. CiteSpace, VOSviewer, and the online bibliometric analysis platform were used to conduct this scientometric study.
    Results: A total of 5518 publications were in 1202 academic journals with 137405 co-cited references in by 5637 institutions from 98 countries/regions. The country leading the research was the USA. The University of Melbourne was the most active institution. Osteoporosis International was the most productive journal concerning exercise and osteoporosis research. According to the burst references, "low-level vibration," "high-frequency" and "resistance exercise" have been recognized as the hotspots research in the domain. The keywords co-occurrence analysis identified "skeletal muscle," "sarcopenia" and "mesenchymal stem cell" as the important future research directions.
    Conclusion: This study was the first comprehensive metrological and statistical analysis of exercise and osteoporosis research over the past 20 years. Our findings would provide guidance to understand the research frontiers and hot directions in the near future.
    Keywords:  VOSviewer; bibliometrics; citespace; exercise; osteoporosis; visualization analysis
    DOI:  https://doi.org/10.3389/fmed.2022.944444
  3. Front Neurol. 2022 ;13 1047162
      Glioma-associated macrophage/microglia (GAM) represents a key player in shaping a unique glioma ecosystem to facilitate tumor progression and therapeutic resistance. Numerous studies have been published concerning GAM, but no relevant bibliometric study has been performed yet. Our bibliometric study aimed to comprehensively summarize and analyze the global scientific output, research hotspots, and trendy topics of publications on GAM over time. Data on publications on GAM were collected using the Web of Science (WoS). The search date was 16 January 2022, and the publications were collected from 2002 to 2021. Totally, 1,224 articles and reviews were incorporated and analyzed in the current study. It showed that the annual publications concerning GAM kept increasing over the past 20 years. The United States had the largest number of publications and total citations. Holland, Kettenmann, and Gutmann were the top three authors in terms of citation frequency. Neuro-oncology represented the most influential journal in GAM studies, with the highest H-index, total citations, and publication numbers. The paper published by Hambardzumyan in 2016 had the highest local citations. Additionally, the analysis of keywords implied that "prognosis," "tumor microenvironment," and "immunotherapy" might become research hotspots. Furthermore, trendy topics in GAM studies suggested that "immune infiltration," "immune microenvironment," "bioinformatics," "prognosis," and "immunotherapy" deserved additional attention. In conclusion, this bibliometric study comprehensively analyzed the publication trend of GAM studies for the past 20 years, in which the research hotspots and trendy topics were also uncovered. This information offered scholars critical references for conducting in-depth studies on GAM in the future.
    Keywords:  bibliometrics; glioblastoma; glioma; macrophage; microglia
    DOI:  https://doi.org/10.3389/fneur.2022.1047162
  4. Saudi Dent J. 2022 Dec;34(8): 681-688
      Purpose: This study aimed to investigate the current state of research on tooth extraction socket preservation. The main aim of this study was to consolidate the research published on extraction socket preservation from 1968 to 2020 in Scopus indexed journals.Methodology: The bibliometric method, a quantitative analysis investigating publishing trends and patterns, was used. Scopus database was used to retrieve the bibliographic records of published scholarly output. The analysis was performed using software and visualization tools like MS Excel, VOSviewer, Cite Space, Biblioshiny (RStudio), and BibExcel.
    Results: The result showed a gradual increase in research, whereby a substantial increase was observed from 2005 to 2006. Six hundred nineteen articles were published in 173 journals with total citations of 12091. Most published articles were from the USA, Italy, Germany, and China. The authorship pattern showed an interdisciplinary and collaborative approach among researchers.
    Conclusion: This bibliometric analysis can guide researchers, funding agencies, industry, and institutions.
    Keywords:  Alveolar ridge preservation; Authorship pattern; Bibliometric analysis; Citation bursts; Dental socket preservation; Research collaboration; Research trends; Scopus research mapping
    DOI:  https://doi.org/10.1016/j.sdentj.2022.09.003
  5. Eur Radiol. 2022 Dec 26.
      OBJECTIVES: The pandemic caused by SARS-CoV-2 has led to the rapid publication of numerous radiology articles, primarily focused on disease diagnosis. The objective of this study is to analyze the intellectual structure of radiology research on COVID-19 using a citation and co-citation analysis.METHODS: We identified all documents about COVID-19 published in radiology journals included in the Web of Science in the period 2020-2021, conducting a citation analysis. Then we identified all bibliographic references that were cited by these documents, generating a co-citation matrix that was used to perform a co-citation network.
    RESULTS: Of the 3418 documents indexed in WoS, 857 were initially "Early Access," 2223 had citations, 393 had more than 20 citations, and 83 had more than 100 citations. The USA had the highest number of publications (32.62%) and China had the highest rate of funded studies (45.38%). The three authors with the most publications were affiliated with Italian institutions, while the five most cited authors were Chinese. A total of 647 publications were co-cited at least 12 times and were published in 206 different journals, with 49% of the documents found in radiology journals. The institutions with the greatest presence among these co-cited articles were Chinese and American.
    CONCLUSION: This co-citation analysis is the first to focus exclusively on radiology articles on COVID-19. Our study confirms the existence of interrelated thematic clusters with different specific weights.
    KEY POINTS: • As the pandemic caused by SARS-Cov-2 has led to the rapid publication of numerous radiology studies in a short time period, a bibliometric review based on citation and co-citation analysis has been conducted. • The co-citation analysis supported the identification of key themes in the study of COVID-19 in radiology publications. • Many of the most co-cited articles belong to a heterogeneous group of publications, with authors from countries that are far apart and even from different disciplines.
    Keywords:  Bibliometrics; Co-citation; Radiology; SARS-CoV-2
    DOI:  https://doi.org/10.1007/s00330-022-09340-y
  6. Cureus. 2022 Dec;14(12): e32903
      OBJECTIVE: In the current study, we analyzed the 100 most cited articles with the topic, title, and keywords of polycystic ovary syndrome (PCOS) published in all journals in terms of traditional metrics and the altmetric score (AS).METHODS: The term "polycystic ovary syndrome (PCOS)" was searched in the Web of Science (WoS) database and filtered for articles published in all journals. Bibliographic data and AS were obtained for 100 highly cited papers from January 2012 to July 2022. Descriptive statistics were reported and correlation analysis between traditional bibliographies and the AS was performed.
    RESULTS: The Journal of Clinical Endocrinology & Metabolism, with 14 articles, had the most publications on the Top 100 list. When the studies were classified according to subtypes, 56 papers were original scientific papers with mean AS of 32.5 (15.3-52.7), whereas 44 papers were reviews and meta-analyses with AS of 16.0 (8.6-43.2). The AS was positively correlated with H-index, total WoS citation number of article and Q category. There were no correlations with impact factor (IF), five-year IF, journal impact factor (JIF) percentile and journal citation indicator (JCI) value.
    CONCLUSION: Our results suggest that the AS is related with article total WoS citation number, journal Q category, and journal H-index. Effective communication on social media can promote scientific productivity and have a positive impact on society.
    Keywords:  altmetric score; pcos; social media; traditional metrics; trend topics
    DOI:  https://doi.org/10.7759/cureus.32903
  7. Orthop J Sports Med. 2022 Dec;10(12): 23259671221141089
      Background: Bibliometric citation analyses have been widely used in medicine to help researchers gain foundational knowledge about a topic and identify subtopics of popular interest for further investigations.Purpose: To identify the 50 most cited research publications related to American football.
    Study Design: Cross-sectional study.
    Methods: The Clarivate Analytics Web of Science database was used to generate a list of publications relating to football. Articles were filtered by the total number of citations, and the top 50 most cited articles studying the sport of football were selected for this analysis. Articles were analyzed by author, publication year, country of origin, institution affiliation, journal, article type, main research topic area, competitive level, and the level of evidence. A total of 247 articles were reviewed to reach the top 50 articles.
    Results: The most studied topic within the top 50 articles was concussion/chronic traumatic encephalopathy (n = 40). Collegiate football was the most studied level of competition (n = 25). The journal publishing the greatest number of top articles was Neurosurgery. Two institutions, the University of North Carolina at Chapel Hill and Boston University School of Medicine, produced over one-third of top 50 articles (n = 18).
    Conclusion: Our analysis indicated that most of the top 50 publications related to the sport of football focused on concussion and CTE, were observational, and were published during or after 2000. The most studied level of competition was collegiate football.
    Keywords:  American football; bibliometric analysis; citation analysis; top-cited articles
    DOI:  https://doi.org/10.1177/23259671221141089
  8. Arq Neuropsiquiatr. 2022 Dec;80(12): 1189-1195
      BACKGROUND:  The impact of a literature report on a particular subject can be measured by its number of citations.OBJECTIVE:  The purpose of this study was to evaluate the characteristics of the literature reports in the field of endovascular treatment of intracranial aneurysms (IAs) by analyzing the top 100 most cited articles. It should be noted that the focus of this study is to describe the bibliometric characteristics.
    METHODS:  This bibliometric analysis dedicated only to endovascular treatment of IAs in our study. We searched the top 100 most cited articles in the field of endovascular treatment of IAs using the search tool of the Web of Science (WOS). We evaluated the characteristics of these high-impact publications, including publication year, category, journal, author's country, etc. RESULTS:  The top 100 most cited articles were cited 281.3 times, on average. The United States has published the most articles every year compared with other countries. These highly cited articles are mostly published in the Journal of Neurosurgery. Eighty-six of the top 100 most cited articles were clinical studies.
    CONCLUSION:  The bibliometric analysis provides insight over the development and the growing trend in endovascular treatment of IAs. This study can help researchers better understand the global overview of this field, and it also provides leads about promising areas of future research and potential collaborations.
    DOI:  https://doi.org/10.1055/s-0042-1758650
  9. Front Neurol. 2022 ;13 1073224
      Background: The establishment of rodent models, such as rat and mouse models, plays a critical role in the study of diabetic associated cognitive decline. With the continuous growth of relevant literature information, it is difficult for researchers to accurately and timely capture the topics in this field. Therefore, this study aims to explore the current status and frontier trends of diabetic associated cognitive decline research based on rat and mouse models through a bibliometric analysis.Methods: We collected 701 original articles on this subject from the Science Citation Index Expanded of the Web of Science Core Collection from 2012 to 2021. Then we utilized CiteSpace and VOSviewer for plotting knowledge maps and evaluating hotpots and trends.
    Results: During this decade, except for a slight decline in 2020, the number of annual outputs on diabetes associated cognitive decline research using rat and mouse models increased every year. China (country), China Pharmaceutical University (institution), Gao, Hongchang (the author from the School of Pharmacy of Wenzhou Medical University, China), and Metabolic Brain Disease (journal) published the most papers in this research field. The analysis results of co-cited references and co-occurrence keywords indicated that "mechanisms and prevention and treatment methods", especially "oxidative stress", "potential association with Alzheimer's disease" and "spatial memory" are research focuses in this subject area. The bursts detection of references and keywords implied that "cognitive impairment of type 1 diabetes" and "autophagy and diabetes associated cognitive decline" will be potential directions for future research in this subject area.
    Conclusion: This study systematically assessed general information, current status and emerging trends of diabetic associated cognitive decline research using rat and mouse models in the past decade based on a bibliometric analysis. The number of publications was annually increasing although a slight decline was observed in 2020. Contributions from different countries/regions, institutions, authors, co-cited authors, journals and co-cited journals were evaluated, which may also be used to guide future research. Through the analysis of references and keywords, we predicted the future research hotspots and trends in this field.
    Keywords:  autophagy; bibliometric; cognitive impairment of type 1 diabetes; diabetic associated cognitive decline; models
    DOI:  https://doi.org/10.3389/fneur.2022.1073224
  10. Heliyon. 2022 Dec;8(12): e12165
      The objective of this scientometric study was to assess the global trends and characteristics of published occupational health research from 2016 to 2020. The SciVal tool (Elsevier) was used to perform the corresponding bibliometric analyses such as the Field-Weighted Citation Impact (FWCI), Source Normalized Impact per Paper (SNIP), CiteScore, and SCImago Journal Rank (SJR). Most of the manuscripts (46.5%) had national collaboration, with an average of 6.1 citations per paper. However, only 71 manuscripts (5.4%) presented single authorship (without collaboration). It was found that 486 manuscripts related to occupational health were published in Q2 journals (top 26-50%). Scientific publications on occupational health have increased remarkably worldwide, especially in Europe, and have mainly been published in Q1 and Q2 journals with a total of 292 and 289 scientific manuscripts in 2019 and 2020, respectively.
    Keywords:  Occupational health; Scientific publications; Scientometrics
    DOI:  https://doi.org/10.1016/j.heliyon.2022.e12165
  11. Environ Sci Pollut Res Int. 2022 Dec 26.
      The emergence of the underlying blockchain technology of bitcoin has gained extensive attention from researchers and practitioners. As distributed ledger technology, blockchain widely finds its applications in the supply chain to mitigate issues related to transparency, information sharing, process efficiency, and traceability. This study employed a knowledge-based visualization technique to create a vision beyond other review studies on the blockchain-based supply chain. We used bibliometric and network analysis to synthesize the previous literature. In total, 431 articles in the timespan of 2017 to April 2022 from Scopus and Web of Science (WOS) databases were analyzed after applying search string, inclusion, and exclusion criteria. Basic information was extracted from initial data screening; then, data was analyzed on the grounds of co-occurrence, bibliographic coupling, citation, co-authorship, and co-citation analysis. In addition, thematic analysis was performed to analyze the content of the previous studies, adopted research methods, and dynamic industries in the literature. Besides all these, we identified various research gaps and proposed research directions for future study. We believe that this study provides adequate knowledge to academic scholars and supply chain practitioners to fast-track the current research in the supply chain domain using blockchain technology.
    Keywords:  Bibliometric analysis; Blockchain; Dynamic industries; Research methodology; Supply chain; Theme analysis
    DOI:  https://doi.org/10.1007/s11356-022-24844-2
  12. Front Cell Infect Microbiol. 2022 ;12 1060031
      Introduction: To analyze the current state, hotspots, and cutting-edge trends of genomics research on the outbreak of Corona Virus Disease 2019 (COVID-19) from 2019 to the present (March 2022).Methods: Statistical and visual analysis of COVID-19 genomics results published in the 2019-2022 Web of Science Core Collection Database (WOSCC) was performed using CiteSpace software, including data on countries, institutions, authors, journals, co-citations, keywords, etc.
    Results: A total of 9133 English literature were included. The number of publications has significantly increased in 2021, and it is expected that this upward trend will last into the future. The research hotspots of COVID-19 revolve around quarantine, biological management, angiotensin-converting enzyme-2, RNA-dependent RNA polymerase, etc. Research frontiers and trends focus on molecular docking, messenger RNA, functional receptor, etc.
    Conclusion: The last two years have seen a significant increase in research interest in the field of novel coronavirus pneumonia genomics.
    Keywords:  COVID-19; CiteSpace software; bibliometric analysis; genomics; research hotspots; visual analysis
    DOI:  https://doi.org/10.3389/fcimb.2022.1060031
  13. World Neurosurg. 2022 Dec 22. pii: S1878-8750(22)01793-4. [Epub ahead of print]
      BACKGROUND: Artificial intelligence (AI) has the potential to augment clinicians' diagnostic and decision-making capabilities. It is well suited to identify patterns and correlations within datasets and may be applied to identify elements of importance in complex and data laden areas such as patient selection, diagnostics, treatment, and outcome prediction. The development of modern neurosurgery has been dependent on major technological advances. In line with this, a growing interest is seen in the use of AI to assist in neurosurgical research and enhance neurosurgical practices.METHODS: A bibliometric analysis of the 50 most cited articles alluding to the use of AI in neurosurgery, from inception until July of 2022, was undertaken using the Web of Science database. Statistical analyses were performed on R.
    RESULTS: The citation count ranged from 29 to 159 (mean: 51.9, SD: 24.8), and the top-cited article was a 2018 systematic review published in World Neurosurgery. Most articles were published after 2015 (85%). The United States was the largest contributing country on the list with 22 articles. Four first and last authors, each, had two or more publications. Female first and last authorship was attributed to 18% and 0% of the articles, respectively.
    CONCLUSIONS: This review highlights the most impactful articles pertaining to AI in the field of neurosurgery. Although female authors were significantly underrepresented on the list, their work was at least as impactful as their male peers. Finally, the striking dominance of articles originating from the developed world raises concerns as to the future of AI in attending to the global health crisis.
    Keywords:  artificial intelligence; bibliometric analysis; gender gap; neurosurgery; women in neurosurgery
    DOI:  https://doi.org/10.1016/j.wneu.2022.12.087
  14. Front Cardiovasc Med. 2022 ;9 1006213
      Background: Maladaptive inflammation is implicated in the development of diabetic cardiomyopathy (DCM). This study aimed to visually analyze the global scientific output over the past two decades regarding research on inflammation associated with DCM.Methods: All relevant articles and reviews were retrieved in the Web of Science (WOS) Core Collection (limited to SCIE) using "inflammation" and "diabetic cardiomyopathy" as search terms. Articles and reviews published from 1 January 2001 to 28 February 2021 were collected. Visualization analysis and statistical analysis were conducted by Microsoft 365 Excel and VOSviewer 1.6.18.
    Results: A total of 578 documents were finally selected for further analysis. The publications regarding inflammation and DCM increased gradually over approximately 20 years. The most prolific country was China, with 296 documents and the most citations (9,366). The most influential author groups were Lu Cai and Yihui Tan who were from the United States. The bibliometric analysis of co-occurrence keywords showed that inflammation in DCM is composed of numerous molecules (NF-κB, NLRP3 inflammasome, Nrf-2, TNF-α, protein kinase C, PPARα, TLR4, p38 mitogen-activated protein kinase, TGF-β, Sirt1, and AKT), a variety of cardiac cell types (stem cell, fibroblast, and cardiomyocyte), physiological processes (apoptosis, oxidative stress, autophagy, endoplasmic reticulum stress, hypertrophy, mitochondrion dysfunction, and proliferation), and drugs (sulforaphane, metformin, empagliflozin, and rosuvastatin).
    Conclusion: Our bibliometric analysis presents the characteristics and trends of inflammation in DCM and shows that research on inflammation in DCM will continue to be a hotspot.
    Keywords:  VOSviewer; Web of Science; bibliometric analysis; diabetic cardiomyopathy; inflammation
    DOI:  https://doi.org/10.3389/fcvm.2022.1006213
  15. Eur J Med Res. 2022 Dec 27. 27(1): 309
      BACKGROUND: Chronic subdural hematoma (CSDH) is a common disease that forms between the dura and arachnoid membranes of the brain. With the development of medications and surgery, significant progress has been made in the diagnosis and treatment of CSDH. However, there is no comprehensive analysis available on CSDH-related studies published in the literature. This study aimed to collect and analyze CSDH-related studies published since the twenty-first century using bibliometric analysis and to summarize the current status of research in this field for the sake of providing systematic data for further study of CSDH.METHODS: CSDH-related studies were searched in the Web of Science Core Collection (WoSCC) database using the Medical Subject Heading (MeSH) term 'chronic subdural hematoma'. Data analysis and visualization were performed by R and CiteSpace software.
    RESULTS: This study retrieved 1424 CSDH-related articles published since the beginning of the twenty-first century. There was a general increase in both the number of published articles and the mean number of citations. The authors, institutions and journals that contributed the most to the field of CSDH were Jianning Zhang, Tianjin Medical University, and world neurosurgery, respectively. The reference co-citation network identified 13 clusters with significant modularity Q scores and silhouette scores (Q = 0.7124, S = 0.8536). The major research categories were (1) evolution of the therapeutic method and (2) the etiology and pathology of CSDH. Keyword analysis revealed that 'middle meningeal artery embolization' was the latest burst keyword.
    CONCLUSIONS: This study identified the most influential countries, authors, institutions and journals contributing to CSDH research and discussed the hotspots and the latest subjects of CSDH research.
    Keywords:  Bibliometric analysis; Chronic subdural hematoma; CiteSpace; Medication; Middle meningeal artery embolization; Surgical treatment
    DOI:  https://doi.org/10.1186/s40001-022-00959-7
  16. Zhen Ci Yan Jiu. 2022 Dec 25. 47(12): 1123-9
      OBJECTIVE: To compare the diversities in the literature characteristics of animal experiments with acupuncture and moxibustion (acu-moxibustion) published in both Chinese and English, so as to summarize the similarities and differences in the reporting content for the animal experiment research with acu-moxibustion in the journals at home and abroad.METHODS: The articles of animal experiments with acu-moxibustion published from 2016 to 2018 were searched from CNKI, Wanfang, SinoMed, PubMed and Web of Science databases. The articles were screened according to the inclusion and exclusion criteria, and the database was established by importing the essential information, e.g. title, author, journal, impact factor, country, year of publication, citation frequency, funding, disease type, as well as the number of observation indicators and charts. The diversity was initially summarized among this type of articles between China and foreign countries.
    RESULTS: A total of 7 515 articles of animal experiments with acu-moxibustion were retrieved and 2 458 articles were eligible in compliance with the inclusion and exclusion criteria. Of them, there were 1 827 articles in Chinese and 631 in English. (1) Among those of Chinese-version, 169 articles (9.25%) were published in Acupuncture Research, listed the first of the article publications. Regarding the impact factor of published journal, Acupuncture Research was ranked the highest (3.187). For those published in English, 78 articles (12.36%) were published in Evidence-based Complementary and Alternative Medicine, listed the top of the article publications. Gastroenterology occupied the highest in terms of the impact factor (17.373) of published journal. (2) The first authors of Chinese-version articles were all from China, distributing in 461 institutions; of which, Beijing University of Chinese Medicine occupied the top for article publications (142 articles, 7.77%). For the English articles, 16 countries were involved regarding the first authors, and the most of them were from China (523 articles, 82.88%), followed by South Korea, Brazil, the United States and Japan. (3) The frequency of citations of Chinese articles was 7.50, which was significantly higher than that of English ones (4.61). (4) The funding supported Chinese and English articles were 1 680 (91.95%) and 569 (90.17%) respectively. (5) In the aspects of disease name and animal model, 135 and 220 diseases were included in Chinese and English articles respectively. The common top 10 diseases referred to 8 categories, i.e. stroke-related diseases, arthritis, Alzheimer's disease, depression, diabetes, spinal cord injury, hypertension and obesity. (6) In terms of the number of indicators, the maximum number was 6 for Chinese-version articles, averagely 2.46, while, it was 12 for English-version ones, 4.02 in average. (7) Among the articles of Chinese-version, the maximum number of charts was 17, and 1 028 articles had 2 to 4 charts, accounting the largest proportion (56.27%). Among those of English-version, the top number of charts was 27, and 347 articles had 4 to 6 charts, occupying the largest proportion (54.99%).
    CONCLUSION: The number of Chinese-version articles for acu-moxibustion experiment research is much higher than that of the English ones, the authorship is led by Chinese and most of the researches are supported by funds. There is less difference in the disease types between Chinese and English articles, but the frequency citation of Chinese articles is obviously higher than that of English ones; while, the numbers of observation indicators and charts in English articles are much more than those of Chinese ones. It is suggested that the great attention has been drawn on the acu-moxibustion experiment researches published in Chinese journals, and the reports of the researches are more complete in English journals.
    Keywords:  Acupuncture and moxibustion; Animal experiment; Bibliometrics
    DOI:  https://doi.org/10.13702/j.1000-0607.20220766
  17. Front Endocrinol (Lausanne). 2022 ;13 1091999
      Introduction: Diabetic erectile dysfunction (DMED) refers to erectile dysfunction secondary to diabetes. Erectile dysfunction is characterized by a persistent inability to achieve and maintain an erection sufficient to permit satisfactory sexual activity.Methods: Based on the Web of Science core collection database, we firstly analyzed the quantity and quality of publications in the field of DMED, secondly profiled the publishing groups in terms of country, institution, author's publication and cooperation network, and finally sorted out and summarized the hot topics of research.
    Results: From 2001 to 2022, a total of 1,403 articles relating to this topic were published in 359 journals. They represent the global research status, potential hotspots, and future research directions. The number of DMED-related publications and citations has steadily increased over the few past decades. Academic institutions from Europe and the United States have played a leading role in DMED research. The country, institution, journal, and author with the most publications were the United States (294), INHA University (39), the Journal of Sexual Medicine (156), and Ryu, Ji-Kan (29), respectively. The most common keywords were erectile dysfunction (796), men (256), diabetes (254), diabetes mellitus (239), prevalence (180), corpus cavernosum (171), dysfunction (155), mellitus (154), nitric-oxide synthase (153), and expression (140). The main keyword-based research topics and hotspots in the DMED field were oral sildenafil, smooth muscle relaxation, nitric oxide synthase, gene therapy, metabolic syndrome, cavernous nerve injury, stem cell, and penile prosthesis.
    Discussion: The terms oral sildenafil, smooth muscle relaxation, nitric oxide synthase, gene therapy, metabolic syndrome, cavernous nerve injury, stem cell, and penile prosthesis will be at the forefront of DMED-related research.
    Keywords:  CiteSpace; VOSviewer; bibliometric analysis; diabetic erectile dysfunction; visualization
    DOI:  https://doi.org/10.3389/fendo.2022.1091999
  18. Eval Program Plann. 2022 Dec 20. pii: S0149-7189(22)00169-0. [Epub ahead of print]97 102215
      Information and communication technologies (ICTs) play an ever-increasing role in improving the efficiency, profitability, and sustainability of microfinance institutions. This paper aims to assess the role of ICTs in the microfinance industry by systematically reviewing the literature with bibliometric methods. In this research, a total of 347 samples (from 1998 to 2021) were selected from the Web of Science database according to the guideline of the systematic review. By performing descriptive statistical analysis, the contributing institutions, countries, journals, authors, as well as influential publications were identified. In the co-citation and co-word analysis section, three primary types of visualization-cluster views, timezone views and timeline viewswere all presented through CiteSpace. It turns out that crowdfunding, P2P lending and mobile banking have been the favorite topics. A central issue is the role of these platforms in entrepreneurship. We also proposed that applying fintech, especially blockchain and other emerging technologies, to promote financial inclusion is one of the future research trends. The findings of this study will be of interest to researchers, managers, policymakers, and evaluators and facilitate them to make well-informed decisions in their respective domains.
    Keywords:  Bibliometric analysis; Information and communication technologies (ICTs); Microfinance; Systematic review
    DOI:  https://doi.org/10.1016/j.evalprogplan.2022.102215
  19. Front Public Health. 2022 ;10 1022810
      Background: The global community has been affected by the coronavirus disease 2019 (COVID-19), which emerged in December 2019. Since then, many studies have been conducted on cardiovascular diseases (CVDs) and COVID-19. The aim of this study was to perform a bibliometric and visual analysis of the published relationship between CVDs and COVID-19.Methods: 1,890 publications were retrieved from the Web of Science Core Collection database on January 5, 2022. Microsoft Office Excel and CiteSpace were then used to carry out scientometric analysis on the relevant literature according to seven aspects: document type, countries/regions, institutions, authors, journals, references, and keywords.
    Results: The research on CVDs and COVID-19 is currently in a period of rapid development, with China, USA, England, and Italy leading the field. There is active cooperation between most countries and institutions. Harvard Medical School stands out among the many institutions not only for the largest number of publications, but also for their high quality. Banerjee A, Solomon SD and Narula J are three representative authors in this field. Frontiers in Cardiovascular Medicine was the journal with the highest number of published studies, and The Lancet was the most cited journal. Two documents with a high degree of significance in this field were identified. Popular research topics in this field are specific diseases, such as acute coronary syndrome and heart failure; pathogenesis related to ACE2, insulin resistance and pericyte; the specific therapeutic drug chloroquine; and clinical characteristics, physical activity, and mental health. ACE2 and NF-κB will be the focus of future research.
    Conclusions: This study provides useful information for the research of CVDs and COVID-19, including potential collaborators, popular research topics, and a reference for more extensive and in-depth research in the future.
    Keywords:  COVID-19; CiteSpace; bibliometrics; cardiovascular diseases; visualization
    DOI:  https://doi.org/10.3389/fpubh.2022.1022810
  20. J Korean Med Sci. 2022 Dec 26. 37(50): e348
      BACKGROUND: The Journal of Korean Medical Science (JKMS) is a weekly periodical published by the Korean Academy of Medical Sciences. JKMS invites global researchers to submit articles covering various areas in general medicine. The present article's aim was to analyze citations of JKMS articles in 2011-2020 for updating editorial policies.METHODS: Citation records of JKMS articles were tracked in Web of Science (WoS), Clarivate® from August 2021 to June 2022.
    RESULTS: In 2011-2020, JKMS published 2,880 articles, including 2,757 (96.0%) ever cited. All reviews (57/57) and 96% of original research reports (2,184 out of 2,264) received at least one citation. Brief communications, opinions, and images were least cited items. Of 36 subject categories covered by JKMS, only biomedical engineering was significantly less advantageous citation-wise. Five articles published in 2012-2017 attracted more than 100 citations. Most other articles were cited less than 50 times. Article categories of nationwide epidemiology, disease or patient registries, clinical trials, and infectious diseases were distinguished as well cited. Of 378 articles published in 2020, 10 were cited at least 100 times; all these ten items were related to severe acute respiratory syndrome coronavirus 2 and coronavirus disease 2019. In the past 5 years, studies on health care laws, management, and some specific topics in clinical specialties were not cited. The citation trends in WoS, Crossref, and Scopus were similar while PubMed Central records were roughly twice less.
    CONCLUSION: Most of JKMS articles are cited during 5 years post publication, with 1.4% non-citation rate. The obtained results suggest that inviting review articles in clinical sciences, research reports on hot medical topics, and nationwide database analyses may attract more author interest and related citations.
    Keywords:  Citation; Crossref, Scopus; Journal of Korean Medical Science; Web of Science
    DOI:  https://doi.org/10.3346/jkms.2022.37.e348
  21. Ann Palliat Med. 2022 Dec 14. pii: apm-22-1111. [Epub ahead of print]
      BACKGROUND: To compare the research hotspots of infections with the Delta and Omicron variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during the coronavirus disease 2019 (COVID-19) pandemic and to identify future research trends.METHODS: Studies about Delta and Omicron variant infections published over the last 3 years were retrieved from the Web of Science (WoS) database. A comparative bibliometric analysis was conducted through machine learning and visualization tools, including VOSviewer, Bibliographic Item Co-Occurrence Matrix Builder, and Graphical Clustering Toolkit. Research hotspots and trends in the field were analyzed, and the contributions and collaborations of countries, institutions, and authors were documented. A cross-sectional analysis of the relevant studies registered at ClinicalTrials.gov was also performed to clarify the direction of future research.
    RESULTS: A total of 1,787 articles distributed in 107 countries and 374 publications from 77 countries focused on the Delta and Omicron variants were included in our bibliometric analysis. The top five productive countries in both variants were the USA, China, the UK, India, and Germany. In 5,999 and 1,107 keywords identified from articles on the Delta and Omicron, the top two frequent keywords were the same: "COVID-19" (occurrence: 713, total link strength: 1,525 in Delta; occurrence: 137, total link strength: 354 in Omicron), followed by "SARS-CoV-2" (occurrence: 553, total link strength: 1,478 in Delta; occurrences 132, total link strength: 395 in Omicron). Five theme clusters from articles on Delta variant were identified: transmission, molecular structure, activation mode, epidemiology, and co-infection. While other three theme clusters were recognized for the Omicron variant: vaccine, human immune response, and infection control. Meanwhile, 21 interventional studies had been registered up to April 2022, most of which aimed to evaluate the immunogenicity and safety of different kinds of vaccines in various populations.
    CONCLUSIONS: Publications and clinical trials related to COVID-19 increased annually. As the first comparative bibliometric analysis for Delta and Omicron variants, we noticed that the relevant research trends have shifted from vaccine development to infection control and management of complications. The ongoing clinical studies will verify the safety and efficacy of promising drugs.
    Keywords:  Bibliometric analysis; Delta variant; Omicron variant; coronavirus disease (COVID); research trends
    DOI:  https://doi.org/10.21037/apm-22-1111
  22. Front Med (Lausanne). 2022 ;9 1071707
      Background: Cesarean section (CS) has become an effective means to solve dystocia and some obstetric complications, and to save the lives of women and perinatal women. Disparities in quality obstetric care and rehabilitation in CS result from differences in health care systems across regions, and more scientific and reasonable rehabilitation programmes and management measures will benefit more parturient and newborns worldwide who must take CS. In this study, we performed a bibliometric analysis to collect a graphical representation of the CS recovery.Methods: A total of 995 documents of CS recovery were retrieved from the Web of Science Core Collection (WOSCC) on December 31, 2021, and then VOS viewer 1.6.18 was used for visual analysis.
    Results: Over the last 20 years, the researches of CS recovery have gradually increased and it will continue to grow in the next period. Anesthesia and Analgesia is the most popular journal in CS recovery. Most of the representative achievements are concentrated in the relevant institutions of European and American countries, Brendan Carvalho and Ian J. Wrench are among the outstanding scholars in this field, but the overall outcome is limited by limited regional work and lack of broad cooperation and representation. "CS," "surgery," "management," "recovery," "enhanced recovery," and "risk factors" are high frequency keywords, and there is a close relationship between "management" and "enhanced recovery" around the CS and they also become one of the key factors to regulate the condition of patients.
    Conclusion: This work firstly analyzed the research condition of CS recovery by a bibliometric analysis. According to the practice guideline, it produces some outstanding representative productions, which involves enhanced recovery after surgery (ERAS) and will continue to be the focus of researchers. More substantive research articles and large-scale clinical studies may greatly enhance the scientific value, and it is necessary to strengthen the ERAS guideline and cooperation between researchers, generate broader consensus and results, and ultimately provide help for CS recovery.
    Keywords:  Web of Science; bibliometric analysis; cesarean section (CS); enhanced recovery after surgery (ERAS); recovery
    DOI:  https://doi.org/10.3389/fmed.2022.1071707
  23. World Neurosurg. 2022 Dec 27. pii: S1878-8750(22)01809-5. [Epub ahead of print]
      BACKGROUND: Bibliometric analyses of the scientific literature have grown increasingly popular in the past few decades. However, patent bibliometric studies - evaluation of technological literature, have not yet been applied in neurosurgery.OBJECTIVE: To perform a pilot patent bibliometric analysis of the top 100 most cited patents in cranial neurosurgery.
    METHODS: The Lens was used to query multiple databases, to select the top 100 cranial neurosurgical patents based upon forward patent citations. These were organized into 9 categories based on technological descriptors and were evaluated based on the earliest priority date, year issued, and expiration status, among others.
    RESULTS: The top 100 most cited patents included technology underlying 3D navigation (n=31), pharmacology and implants (n=20), vascular occlusion (n=5), craniotomy closure (n=9), focal lesioning and tissue resection (n=8), brain and systemic cooling (n=5), neuroendoscopy (n=8), neuromonitoring and stimulation (6), and technologies improving surgeon performance (n=8). 96 patents were filed in the United States, 72 were expired, 19 are still active, and 9 were listed as inactive. The highest number of patents were applied for from the mid-1990s to the mid-2000s. Demonstrated trends showed no meaningful correlation between patent rank and earliest priority date (linear trendline y=0.7107x-1367.5; R2 = 0.0671), while a very strong correlation was found between patent rank and citations per year (power trendline y=127.93x-1.094; R2=0.8579).
    CONCLUSION: Patent bibliometrics allow evaluation of neurosurgical advancements from the past and enable subsequent development of cutting-edge technology in the future. The described method is a reproducible and reliable technique for evaluating our field's patent literature.
    Keywords:  Bibliometrics; Brain Surgery; Patent; Relevancy
    DOI:  https://doi.org/10.1016/j.wneu.2022.12.103
  24. Scientometrics. 2022 Dec 21. 1-8
      A well-written and interesting article was published on November 21, 2021. Future relevant studies, however, may be improved by implementing (1) a framework that outlines the overall research; (2) an author-weighted scheme (AWS) that accurately quantifies the contributions of entities to articles; and (3) a more appropriate size for the nodes representing the proportional counts for each entity in social network analysis (SNA). VOSviewer was used to construct and visualize the scientometric networks and the relation-based analyses included three categories: (1) citation relations, (2) word cooccurrences, and (3) coauthorship relations. Nevertheless, the counts for each topical entity have not been consistently integrated. As a result, the nodes of the keyword co-occurrence network are large when compared to the number of connections between the entities or terms (i.e., the total number of relationships between co-occurring terms or entities). Additionally, all weighted counts in keywords (or the total link strength of a country/region) should equal the total number of documents (e.g., n = 9954 in that article). This would lead to biases in the calculation of publications (or citations) for entities, as is common in traditional SNA. This node illustrates a study framework and a couple of AWSs (i.e., equal and nonequal AWSs) to improve the article, and discusses the need to understand the requirement that the total centrality degree in SNA equals the total number of documents (or citations).
    Keywords:  Author-weighted scheme; Citation; Publication; Social network analysis; Study framework; VOSviewer
    DOI:  https://doi.org/10.1007/s11192-022-04600-6
  25. Yakugaku Zasshi. 2022 Dec 27.
      Since the early 2000s, Japan has been frequently noted as being the only country among about 20 major countries where the publication of academic papers has stagnated. During this period, there have been major changes especially with regards to the Japanese pharmacy schools, such as the shift to a six-year schooling system and the rapid increase in the number of private pharmacy schools. However, few studies have focused on academic productivity specifically among pharmacy schools. Therefore, this study analyzed the outputs associated with the publication of peer-reviewed scholarly articles in Scopus search engine per faculty member in pharmacy schools nationwide in 2020. Professors, associate professors, and lecturers were considered as faculty members. The average number of papers published per the faculty member was 3.13 for national and public universities and 1.15 for private universities, with a significant difference between these universities. Dividing the pharmacy schools of private universities into schools established after 2003 and schools established before that, the production coefficient of the former was 0.98 and that of the latter was 1.33. Newly established pharmacy schools were thus found to be slightly less productive in terms of published papers than traditional schools. The paper productivity of private university pharmacy schools is stagnant; the increase in the number of private schools that have adopted a six-year schooling system has contributed to large extent to the creation of clinically competent pharmacists, but it has also brought to light concerns related to the decline in basic research capabilities of Japanese pharmaceutical academia.
    Keywords:  academic paper; newly established school; pharmacy school; research productivity
    DOI:  https://doi.org/10.1248/yakushi.22-00149
  26. Acad Med. 2023 Jan 01. 98(1): 75-79
      PURPOSE: There continues to be a disparity in the representation of women across medicine, including in editor positions at major medical journals. The authors repeated a study they had conducted in 2011 to compare the representation of women in editor-in-chief and editorial board member positions in 2011 and 2021.METHOD: The authors included in their analysis the 60 journals from their original 2011 study and the top 5 ranked journals by Journal Impact Factor in each of 12 disciplines in 2021. This led to the inclusion of 86 journals. The authors collected the names and genders of the editors-in-chief and editorial board members at these journals, using information provided by the journals and a Google search for the photos and/or pronouns of the remaining editors. They compared results across years (2021 vs 2011), editor positions, disciplines, Journal Impact Factors, and ranks.
    RESULTS: Twenty-two of the 90 editors-in-chief (24.4%) were women in 2021 compared with 10 of 63 (15.9%) in 2011, an increase of 8.5%. Of the 6,285 editorial board members, 1,756 were women (27.9%) in 2021 compared with 719 of 4,112 (17.5%) in 2011, an increase of 10.4%. Journals with women editors-in-chief gained 3.5 ranks and 9.1 points in Journal Impact Factor on average over this 10-year period, compared with no gain in rank and an increase of 4.7 points in Journal Impact Factor for journals with men editors-in-chief; both are statistically significant differences (P = .045 and P = .016, respectively).
    CONCLUSIONS: In almost all evaluated disciplines and editor positions, there was an increase in the percentage of women at top-ranked medical journals over a 10-year period. Despite this increase, improvements are still needed to accelerate the currently slow rate of change in these positions to enhance diversity, equity, and inclusion for women in medicine.
    DOI:  https://doi.org/10.1097/ACM.0000000000004964
  27. Health Commun. 2022 Dec 29. 1-15
      As an emerging form of health care with accelerated growth in recent years, online medical consultation (OMC) has received extensive attention worldwide. Although the number of studies on OMC has increased substantially, few provide a comprehensive and up-to-date review of OMC's research constituents, themes, and trends. This study, therefore, extracted 1,801 OMC-related articles published in English from the Web of Science (WoS) Core Collection database during the past 30 years and employed a bibliometric analysis of WoS and CiteSpace to examine major constituents' distribution, collaboration relationships, themes, and trends. The results indicate that the United States, England, and China contributed the most to the proliferation of OMC studies. The United States had the greatest academic influence and the most collaborative connections, while China demonstrated the sharpest increase and most active development in recent years. However, there is a lack of substantial and close collaboration between researchers worldwide. The main themes of OMC research were Internet hospitals, COVID-19, mixed methods, online health community, and information technology. Researchers have recently shifted their attention to social media, management, efficacy, word of mouth, mental health, and anxiety. This review paper provides researchers and practitioners with a holistic and clear understanding of the features and trends of OMC research. It also identifies potential areas for future OMC research and sheds light on OMC practices.
    DOI:  https://doi.org/10.1080/10410236.2022.2163108
  28. Aesthetic Plast Surg. 2022 Dec 29.
      BACKGROUND: Understanding country differences in production and human capital in plastic surgery research is crucial in identifying current and future leaders in the field. In this study, we document each country's human capital and productivity in plastic surgery research.METHODS: A web scraping algorithm was deployed on PubMed to retrieve information on every publication and every first author in 10 major research outlets in plastic surgery between 2015 and 2021. Each country's human capital in the field is proxied by the number of first authors affiliated with that country. We compare aggregate patterns and volume trajectories of publications affiliated with 110 countries in the context of their human capital.
    RESULTS: We find that over the studied period, two countries, the USA and China, are represented in roughly 50% and 45% of global research output and first authors, respectively, in plastic surgery. Specifically in the USA, California has the highest number of affiliated first authors and publications compared with other States.
    CONCLUSIONS: Our findings reveal the clear dominance of the USA in plastic surgery research production. No specific US State stands out in the nation as much as the USA does in the global ranking of plastic surgery publications. This suggests that US plastic surgeons across the nation aim to publish. Our global analysis also suggests that countries with a higher share of first authors relative to their research output may have greater capacity to expand their research output in the future.
    LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
    Keywords:  First authors; Human capital; Plastic surgery; Publications; Research productivity; Web scraping
    DOI:  https://doi.org/10.1007/s00266-022-03223-9
  29. Front Oncol. 2022 ;12 995639
      Background: Patients with glioma present with complex palliative care needs throughout their disease trajectory. A scientometric analysis is effective and widely used to summarize the most influential studies within a certain field. We present the first scientometric analysis of palliative care for patients with glioma.Methods: Based on a Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) principle, we conducted a generalized search for articles on palliative care for glioma in the Web of Science database and evaluated the top 100 most frequently cited articles among 2,542 articles.
    Results: The number of citations for the top 100 cited articles on palliative care for glioma ranged from 10 to 223. We have a narrative conclusion, as follows: most of these articles were published in oncology-specific journals (n = 53) and palliative-specific journals (n = 22). The United States, Australia, and the Netherlands were the top three countries contributing most of the articles (n = 59). Most of the research methods were quantitative analyses, qualitative analyses, and systematic reviews and meta-analyses (n = 70). In quantitative studies, 66 scales were used, and the top three scales used included the following: the Distress Thermometer, Functional Assessment of Cancer Therapy-Brain Index (FACT-Br), and Karnofsky Performance Scale (KPS). The articles were classified into six major categories based on research subjects, including patients (n = 44), caregivers (n = 16), patients and caregivers (n = 20), literature (n = 19), and healthcare providers (n = 1). Articles were classified into seven major categories based on research themes: quality of life (n = 11); end-of-life symptoms and care (n = 16); palliative and supportive care needs (n = 35); advance care planning and decision making (n = 4); psychological, social, and spiritual needs (n = 12); hospice utilization and referral (n = 3); and others (n = 19). The studies of the primary topic are correlated with the number of citations.
    Conclusions: The results of the analysis indicated that patients diagnosed with glioma present a high variety of palliative care needs, including physical, psychological, social, and spiritual needs. The caregiver's burden and needs are important as well. The proportion of quantitative analyses, qualitative analyses, and systematic reviews and meta-analyses is relatively high, but the number of randomized controlled trials (RCTs) was low. End-of-life care and supportive care needs appeared frequently. Thus, palliative care is an urgent need to be addressed in glioma management. The appropriate scales should be selected for patients with glioma and meet their palliative needs.
    Keywords:  citation classics; citations; glioma; hospice care; palliative care; scientometric analysis
    DOI:  https://doi.org/10.3389/fonc.2022.995639
  30. Int J Dev Disabil. 2022 ;68(6): 809-823
      Special education is a natural yardstick to measure a country's educational level and the whole civilization. China has a massive special education undertaking that develops rapidly and forms a unique system. This study used bibliometric methods to conduct a macroscopic comparative analysis of Chinese and global literature, discuss the existing problems of China's special education, and put forward relevant recommendations accordingly. The CiteSpace V visual analysis software was used to draw the scientific knowledge map of the Chinese local database CSSCI and the global database SSCI, and the results of the map were discussed. Research conclusions: Firstly, China's research institutions lack a macro-level cooperation network. Second, there are differences in the focus of special education objects between China and the world. This difference is mainly caused by the definition of special education objects, which may be influenced by the formulation of educational concepts and policies. Thirdly, in the reference co-citation analysis, the focus of Chinese research is narrow and generally focuses on special education teachers. This article provides implications for solving special education problems in China, and its research method provides a reference for future related research for other countries.
    Keywords:  Special education; burst phrases; co-occurrence; mapping knowledge domains; reference co citation; research hotspots
    DOI:  https://doi.org/10.1080/20473869.2021.1895697
  31. Front Psychol. 2022 ;13 1072494
      Introduction: I investigated the authorship gender gap in research on political psychology.Methods: The material comprises 1,166 articles published in the field's flagship journal Political Psychology between 1997 and 2021. These were rated for author gender, methodology, purpose, and topic.
    Results: Women were underrepresented as authors (37.1% women), single authors (33.5% women), and lead authors (35.1% women). There were disproportionately many women lead authors in papers employing interviews or qualitative methodology, and in research with an applied purpose (these were all less cited). In contrast, men were overrepresented as authors of papers employing quantitative methods. Regarding topics, women were overrepresented as authors on Gender, Identity, Culture and Language, and Religion, and men were overrepresented as authors on Neuroscience and Evolutionary Psychology.
    Discussion: The (denigrated) methods, purposes, and topics of women doing research on politics correspond to the (denigrated) "feminine style" of women doing politics grounding knowledge in the concrete, lived reality of others; listening and giving voice to marginalized groups' subjective experiences; and yielding power to get things done for others.
    Keywords:  authorship; gender differences; gender gap; political psychology; research profession
    DOI:  https://doi.org/10.3389/fpsyg.2022.1072494
  32. J Neurosurg. 2022 Dec 30. 1-11
      OBJECTIVE: The Neurosurgery Research and Education Foundation (NREF) provides diverse funding opportunities for in-training and early-career neurosurgeon-scientists. The authors analyzed the impact of NREF funding on the subsequent career success of neurosurgeons in obtaining research funding and academic achievements.METHODS: The NREF database was queried to identify NREF winners from 2000 to 2015. The award recipients were surveyed to obtain information about their demographic characteristics, academic career, and research funding. Only subsequent research support with an annual funding amount of $50,000 or greater was included. The primary outcome was the NREF impact ratio, defined as the ratio between NREF award research dollars and subsequent grant funding dollars. The secondary outcomes were time to subsequent grant funding as principal investigator (PI), clinical practice settings, and final academic position achieved.
    RESULTS: From 2000 to 2015, 158 neurosurgeons received 164 NREF awards totaling $8.3 million (M), with $1.7 M awarded to 46 Young Clinician Investigators (YCIs), $1.5 M to 18 Van Wagenen Fellows (VWFs), and $5.1 M to 100 resident Research Fellowship Grant (RFG) awardees. Of all awardees, 73% have current academic appointments, and the mean ± SD number of publications and H-index were 71 ± 82 and 20 ± 15, respectively. The overall response rate to our survey was 70%, and these respondents became the cohort for our analysis. In total, respondents cumulatively obtained $776 M in post-NREF award grant funding, with the most common sources of funding including the National Institutes of Health ($327 M) and foundational awards ($306 M). The NREF impact ratios for awardees were $1:$381 for YCI, $1:$113 for VWF, and $1:$41 for resident RFG. Awardees with NREF projects in functional neurosurgery, pediatric neurosurgery, and neuro-oncology had the highest NREF impact ratios of $1:$194, $1:$185, and $1:$162, respectively. Of respondents, 9% became department chairs, 26% became full professors, 82% received at least 1 subsequent research grant, and 66% served as PI on a subsequent research grant after receiving their NREF awards.
    CONCLUSIONS: In-training and early-career neurosurgeons who were awarded NREF funding had significant success in acquiring subsequent grant support, research productivity, and achievements of academic rank. NREF grants provide a tremendous return on investment across various career stages and subspecialities. They also appeared to have a broader impact on trajectory of research and innovation within the field of neurosurgery.
    Keywords:  AANS; NREF; academic neurosurgery; career outcomes; physician-scientist; research funding
    DOI:  https://doi.org/10.3171/2022.11.JNS221391
  33. Front Psychol. 2022 ;13 977130
      Executives' unethical behaviour is a common phenomenon in business practice and a hot topic for academic research, which has a profound negative impact on the healthy development of our economy and society. In the past two decades, several scholars from different disciplines con-ducted theoretical research and practical explorations on the issue of senior executives' (un)ethical behaviour and achieved certain research results. However, the existing research in this field still has problems, such as a lack of systematic integration of research results, unclear research hotspots and unclear development directions. Thus, the present study through a bibliometric analysis, conducted a content coding of these 428 papers identified from 2000 to 2020, constructed a theoretical framework by inductively identifying the corresponding concepts. By reviewing the progress of existing research topics, this study summarised a research framework of executives' unethical behaviour from the perspectives of the antecedents, the behaviour itself and the consequences of unethical behaviour. The study further proposed future research trends and recommendations for conducting research on executives' unethical behaviour under emerging market scenarios. The research results provide new ideas for developing the theory of executives' unethical behaviour and promote the in-depth development of the research on executives' unethical behaviour in the context of emerging markets.
    Keywords:  emerging markets; executives’ unethical behaviour; immoral activity; literature research; theoretical framework
    DOI:  https://doi.org/10.3389/fpsyg.2022.977130
  34. J Surg Educ. 2022 Dec 27. pii: S1931-7204(22)00337-3. [Epub ahead of print]
      OBJECTIVE: Better understanding the research productivity of Canadian general surgery residents and factors associated with success would provide a valuable reference and help inform actions to enable success. We aimed to characterize the research productivity of Canadian general surgery residents and to evaluate factors associated with residents' research quantity and impact.DESIGN: A cross-sectional, observational study was performed using publicly available data evaluating Canadian General Surgery resident research productivity. Research productivity was characterized using measures including publications per postgraduate year (PGY) and CiteScore among others. Residency programs were then comparatively assessed using a multivariable logistic regression to evaluate program and resident factors associated with achieving >50th percentile research productivity.
    SETTING AND PARTICIPANTS: All General Surgery residents from English speaking Canadian training programs were included in this study, which was completed at the University of Alberta, a tertiary level academic center in Edmonton, Canada.
    RESULTS: A wide range of resident research productivity was observed across Canada with the median publications per PGY of 0.29, and the median sum of a resident's publication CiteScores of 2.05. The median h-index was 0.90. Graduate degree completion and publication experience prior to residency were significantly associated with higher publications per PGY (OR 2.94 and OR 2.10, respectively), as well as higher mean CiteScore (OR 3.42 and 2.24). The program factors that were assessed, including program size, research blocks, mandatory projects, or higher staff research productivity, did not show significant association with increased research output.
    CONCLUSIONS: There is a wide range in research output by general surgery residents across the country. Successful completion of graduate degrees and the experience of publication prior to residency are associated with higher research productivity and impact.
    Keywords:  Research Productivity; Residency Programming; Surgical Education; Surgical Research
    DOI:  https://doi.org/10.1016/j.jsurg.2022.12.005
  35. Heliyon. 2022 Dec;8(12): e12253
      Antibiotic resistance genes (ARGs) and Mobile genetic elements (MGEs) are major global emerging pollutants of the environment and water nexus which various investigators of related studies have reported. Observing ARGs and MGEs in water bodies, wastewater treatment systems, and estuaries is indicative of relevant risk, resistant bacteria/ARGs spread or potential health concern and may result environmental pathogen bloom if appropriate research-based strategies are not implemented to remove these lethal genetic materials. Despite reports and knowledge-based strategies for removal, the challenge yet persists. This study aims to appraise the impact/contribution of related studies and emphasize the necessity for applying combined research-based/practitioners approach in addressing the expanding challenge of ARGs/MGEs in wastewater/waterbodies. The study describes a bibliometric assessment of antibiotic resistance determinants annual scientific publications on the Web of Science, an annual growth rate of related articles, top articles per citations with search topics and content-review analysis to evaluate the methods of removal of ARGs/MGEs. A total of 1301 articles of wastewater treatment systems were retrieved with date range of 1997-2019. A description of the study Annual Growth Rate of 37.82% at R2 of 0.7863 was observed with an increasing article publication and a decreasing total citation rate indicating persistent reports of dispersion on ARGs/MGEs studies in the water bodies and environment. Although there abound extensive studies and reports of ARGs and MGEs in water nexus and wastewater release with research based removal strategies, the impact of such reports have not been fully actualized amongst wastewater system practitioners. A lucid drive towards implementing ARGs/MGEs removal strategies from the environment by applying affirmed research-based methods are suggestive.
    Keywords:  Antibiotic resistant genes (ARGs); Articles citation; Mobile genetic elements (MGEs); Research assessment; Wastewater treatment systems; Water environments
    DOI:  https://doi.org/10.1016/j.heliyon.2022.e12253
  36. Reumatismo. 2022 Dec 29. 74(3):
      Rheumatology is a field in which diagnostic, pathophysiological, and therapeutic advancements occur daily. These developments are the result of research in basic sciences, translational sciences, and clinical sciences. Physical and financial support, provided by individuals and institutions, is essential for all types of research. The political and economic instability in the Arab world has impacted the advancement of healthcare and the output of research. This review seeks to evaluate the quantity and quality of rheumatology-related research conducted in the Arab world. This review examined the number of rheumatological clinical publications produced by Arab countries between 2017 and 2021 and cited by PubMed/MEDLINE. Publications with authors from multiple nations were disqualified. Publications were then categorized by type, including randomized controlled trials (RCTs), cohort studies, cross-sectional studies, systematic reviews, narrative reviews, and case reports. Publications were also organized according to the regions of the Arab world: North and East Africa, the Middle East, and the Arabian Peninsula. The review also used data from the world bank to evaluate the gross domestic product (GDP) and total population of Arabian nations in order to calculate a ratio of publications to GDP and publications to population. Egypt had the highest number of publications among north and east African countries and Arab countries in general, with 261 publications, including the highest number of RCTs, which were 23. With 81 publications, Saudi Arabia had the highest number of publications on the Arabian peninsula. However, no individual country on the Arabian peninsula published an RCT. Lebanon had the most publications in the Middle East, but the majority were reviews and case reports. Tunisia had the highest ratio of publications to GDP. Notably, the number of publications increased during the coronavirus disease 2019 era in some countries. The Arab world is still able to produce clinical rheumatology publications despite its political instability and lack of resources. The influence of such publications on the daily practice of rheumatology is still debatable.
    DOI:  https://doi.org/10.4081/reumatismo.2022.1520
  37. Sustain Cities Soc. 2021 Oct;73 103126
      This paper presents the results of a bibliometric analysis of academic research dealing with COVID-19 in the area of city destination development from 1 December 2019 to 31 March 2021. Particularly, by means of SciMAT software, it identifies, quantifies, and visually displays the main research clusters, thematic structure and emerging trends that city and tourism planners will face in the new normal. The search revealed that social media and smart tourism are the themes with the greatest potential; sustainable cities, local destination development, changes in tourist behavior, and tourists' risk perception are underdeveloped streams with enormous relevance and growth in the new normal. Research on the effects of COVID-19 on citizen health and its economic impact on the tourism industry and cities are intersectional and highly developed topics, although of little relevance. The current study also identifies the challenges of destination research for planners and proposes future research directions. Consequently, this paper contributes to the existing literature on COVID-19 and sustainable cities, as it develops a critical examination of the extant research and points out the research gaps that must be filled by future studies.
    Keywords:  COVID-19; Co-word analysis; Local development; Smart cities; Sustainable cities; Tourism industry
    DOI:  https://doi.org/10.1016/j.scs.2021.103126
  38. East Mediterr Health J. 2022 Dec 21. 28(12): 863-871
      Background: Multiple sclerosis is a complex and intractable neurological disease associated with substantial morbidity, healthcare utilization, management cost, and loss of productivity. There has been an alarming increase in the number of multiple sclerosis cases in Arab countries in recent years, which has spurred an increase in local research.Aims: To analyse the multiple sclerosis research profile in Arab countries.
    Methods: A total of 781 publications focusing on multiple sclerosis research in Arab countries from 1983 to 2021 were extracted from the Web of Science database and analysed using bibliometric techniques.
    Results: Publication on multiple sclerosis research increased sharply in the last decade, globally and in the Arab countries. However, Arab countries have only contributed 0.8% of the overall number of publications. Keyword pattern analysis showed that magnetic resonance imaging, optical coherence tomography, expanded disability status, demyelination, and epidemiology were the major themes of multiple sclerosis research in Arab countries. Case-control, cohort, and descriptive studies were the most prevalent study designs. However, there was a notable paucity of meta-analyses, randomized controlled trials, and clinical trials.
    Conclusion: Arab countries can improve their regional expertise and add a wealth of knowledge to global multiple sclerosis resources by diversifying their current research initiatives, and tracking recent advances in pathogenesis, diagnosis, and management of multiple sclerosis.
    Keywords:  Arab countries; Web of Science; neurology; research; scientometrics; sclerosis
    DOI:  https://doi.org/10.26719/emhj.22.092
  39. Behav Sci Law. 2022 Dec 29.
      Misinformation is widespread in political discourse, mental health literature, and hard science. This article describes recurrent publication of the same misinformation regarding parental alienation (PA), that is, variations of the statement: "PA theory assumes that the favored parent has caused PA in the child simply because the child refuses to have a relationship with the rejected parent, without identifying or proving alienating behaviors by the favored parent." Ninety-four examples of the same misinformation were identified and subjected to citation analysis using Gephi software, which displays the links between citing material and cited material. The recurrent misinformation reported here is not trivial; these statements are significant misrepresentations of PA theory. Plausible explanations for this trail of misinformation are the psychological mindset of the authors (i.e., confirmation bias) and the authors' writing skills (e.g., sloppy research practices such as persistent use of secondary sources for their information). The authors of this article recommend that publications containing significant misinformation should be corrected or retracted.
    Keywords:  citation analysis; disinformation; misinformation; parental alienation theory; retraction
    DOI:  https://doi.org/10.1002/bsl.2605
  40. Scientometrics. 2022 Dec 17. 1-25
      Keeping track of translational research is essential to evaluating the performance of programs on translational medicine. Despite several indicators in previous studies, a consensus measure is still needed to represent the translational features of biomedical research at the article level. In this study, we first trained semantic representations of biomedical entities and documents (i.e., bio-entity2vec and bio-doc2vec) based on over 30 million PubMed articles. With these vectors, we then developed a new measure called Translational Progression (TP) for tracking biomedical articles along the translational continuum. We validated the effectiveness of TP from two perspectives (Clinical trial phase identification and ACH classification), which showed excellent consistency between TP and other indicators. Meanwhile, TP has several advantages. First, it can track the degree of translation of biomedical research dynamically and in real-time. Second, it is straightforward to interpret and operationalize. Third, it doesn't require labor-intensive MeSH labeling and it is suitable for big scholarly data as well as papers that are not indexed in PubMed. In addition, we examined the translational progressions of biomedical research from three dimensions (including overall distribution, time, and research topic), which revealed three significant findings. The proposed measure in this study could be used by policymakers to monitor biomedical research with high translational potential in real-time and make better decisions. It can also be adopted and improved for other domains, such as physics or computer science, to assess the application value of scientific discoveries.
    Keywords:  Bibliometrics; Biomedical knowledge representation; Indicator; Research evaluation; Translational Progression
    DOI:  https://doi.org/10.1007/s11192-022-04607-z
  41. Arthrosc Sports Med Rehabil. 2022 Dec;4(6): e2035-e2042
      Purpose: To investigate the characteristics of shoulder and elbow fellowship directors (FDs).Methods: FDs for shoulder and elbow fellowship programs in the United States were identified. Demographic, educational, and professional background data were collected from available curricula vitarum, institutional biographies, and the Scopus database. Data collected included age, sex, race/ethnicity, training locations, graduation years, advanced degrees, current institutional information, and personal research H-index.
    Results: Thirty current orthopaedic shoulder and elbow FDs were identified. The mean Scopus H-index was 25.5. The mean age of FDs was 52.1 years. In total, 29 FDs (96.7%) were male and 1 (3.3%) was female. In addition, 25 of the 30 (83.3%) were White (83.3%), 4 were Asian, and 1 (3.3%) was Hispanic. Two (6.7%) had a military affiliation. Mean time from fellowship training graduation to FD appointment was 13.5 years. Mean number of years as FD was 6.1 years, whereas the number of years tenure with an FD-affiliated institution was 13.0 years. Mean calendar years for completion of orthopaedic residency training and fellowship training were 1998 and 2000, respectively. The residencies that produced the most future FDs were Hospital of the University of Pennsylvania (n = 2) and University of Nebraska Medical Center/Creighton University Health Foundation (n = 2). The fellowship that produced the most future FDs was Columbia University (n = 6). Moderate correlation was found between age and Scopus H-index (r = 0.48; P = .04) and years as FD and Scopus H-index (r = 0.42; P = .03).
    Conclusions: Women and minorities are under-represented in leadership positions in shoulder and elbow surgery. Shoulder and elbow FDs have the highest H-index of any subspecialty reported in the orthopaedic literature. Research productivity is an important qualification when considering the characteristics of shoulder and elbow FDs.
    Clinical Relevance: Fellowship directors can have a profound influence on current and future orthopaedic surgeons. It is important to identify the traits that characterize current fellowship directors to have a better understanding of who we choose as leaders in our field.
    DOI:  https://doi.org/10.1016/j.asmr.2022.08.011
  42. Front Immunol. 2022 ;13 1098082
      [This corrects the article DOI: 10.3389/fimmu.2022.1025861.].
    Keywords:  CiteSpace; NETs; VOSviewer; neutrophil; visual analysis
    DOI:  https://doi.org/10.3389/fimmu.2022.1098082