bims-evares Biomed News
on Evaluation of research
Issue of 2023‒01‒08
fifty-two papers selected by
Thomas Krichel
Open Library Society


  1. Rom J Ophthalmol. 2022 Oct-Dec;66(4):66(4): 326-336
      Objective: The number of citations is used for the scholarly impact of a published article, but it does not always correlate with higher-quality research. Behçet's disease (BD) is a debilitating-blinding disorder with a significant volume of published articles in literature. Our aim was to investigate the references of the 50 most-cited Behçet articles and to evaluate the relationship between altmetric attention score (AAS) and additional metrics. Methods: The Web of Science (WoS) core collection was used to search for the 50 most-cited Behçet articles. Additional metrics and AAS of the reviewed articles and the journals in which the articles were published, were evaluated. Results: A total of 11.372 published articles on BD, between 1975 and 2022, were found. The citation range of 50 highly-cited articles was between 172 and 1322. The "top 50 list" articles were published between 1988 and 2018, and the average age of the article since publication was 18.86 ± 6.08 years. Rheumatology journals were the most published category with 21 articles. There was a weak-to-moderate correlation between AAS and additional metrics. Conclusions: This is the first analysis regarding the AAS of the 50 most-cited articles on BD, which provides useful information about the social impact and characteristics in the academic community. AAS correlates weakly with citation-based quality indexes, and moderately with immediacy index, which evaluates speed. The publication year should be considered when comparing or evaluating the AAS of articles. AAS could be evaluated in a secondary plan for scientific impact analysis.
    Keywords:  Behçet; altmetric attention score; eigenfactor score; immediacy index; impact factor
    DOI:  https://doi.org/10.22336/rjo.2022.59
  2. Front Endocrinol (Lausanne). 2022 ;13 1032144
      Purpose: To comprehensively analyze and discuss the publications on machine learning (ML) in diabetic retinopathy (DR) following a bibliometric approach.Methods: The global publications on ML in DR from 2011 to 2021 were retrieved from the Web of Science Core Collection (WoSCC) database. We analyzed the publication and citation trend over time and identified highly-cited articles, prolific countries, institutions, journals and the most relevant research domains. VOSviewer and Wordcloud are used to visualize the mainstream research topics and evolution of subtopics in the form of co-occurrence maps of keywords.
    Results: By analyzing a total of 1147 relevant publications, this study found a rapid increase in the number of annual publications, with an average growth rate of 42.68%. India and China were the most productive countries. IEEE Access was the most productive journal in this field. In addition, some notable common points were found in the highly-cited articles. The keywords analysis showed that "diabetic retinopathy", "classification", and "fundus images" were the most frequent keywords for the entire period, as automatic diagnosis of DR was always the mainstream topic in the relevant field. The evolution of keywords highlighted some breakthroughs, including "deep learning" and "optical coherence tomography", indicating the advance in technologies and changes in the research attention.
    Conclusions: As new research topics have emerged and evolved, studies are becoming increasingly diverse and extensive. Multiple modalities of medical data, new ML techniques and constantly optimized algorithms are the future trends in this multidisciplinary field.
    Keywords:  bibliometric analysis; diabetic retinopathy; global publication trend; machine learning; topic analysis
    DOI:  https://doi.org/10.3389/fendo.2022.1032144
  3. Medicine (Baltimore). 2022 Dec 30. 101(52): e32513
      BACKGROUND: Cryoablation is an interdisciplinary, widely used treatment approach for several types of solid tumors, making it difficult to obtain a comprehensive picture of its current status and popular research topics. This study aimed to use a bibliometric approach to understand important research themes and trends in cryoablation and oncology.METHODS: Literature studies on cryoablation and oncology from 2001 to 2020 were extracted from the Web of Science. A bibliometric analysis was performed based on the annual publication volume, several journal articles and local citation score, and distribution of keywords and trends in the literature using tools such as COOC version 9.94, VOSviewer version 1.6.17, and the bibliometrix version 3.1.3 R package.
    RESULTS: This study included 2793 publications. Total yearly publications have plateaued over the last 20 years. Five research themes were presented in the keyword network, including clinical applications of cryoablation in liver, lung, kidney, prostate, and skin cancers and comparison of cryoablation with other energy ablations. After 2012, 2 new research topics emerged: synergy between cryoablation and immunotherapy in tumors and cryoablation of Barrett esophagus. The high cited literatures are dominated by studies related to cryoablation for renal and prostate cancer treatment, but they also reflect the recent increasing interest in immunotherapy and bone metastases. Twenty important journals were identified, with Cryobiology publishing the most articles.
    CONCLUSION: Bibliometric analysis of studies related to tumor cryoablation can help researchers rapidly comprehend popular topics and determine future trends, guiding future research directions.
    DOI:  https://doi.org/10.1097/MD.0000000000032513
  4. Neurospine. 2022 Dec;19(4): 1093-1107
      OBJECTIVE: With the advancement of minimally invasive spine surgery, endoscopic discectomy (ED) has become a common technique for degenerative disease of the spine. The present study aimed to explore the knowledge structure, emerging trends, and future research hotspots in this field.METHODS: All relevant publications on ED from 2002 to 2021 were extracted from the Web of Science databases. Key bibliometric indicators, including countries/regions, institutions, authors, journals, references, and keywords were calculated and evaluated using VOSviewer and CiteSpace software.
    RESULTS: A total of 1,196 articles and reviews were included for analysis. The number of publications regarding ED increased yearly. From the quality and quantity viewpoint, China, South Korea, and the United States were the major contributors in this field. The most influential institution in the field of ED was Wooridul Spine Hospital. We identified 3,488 authors, among which Lee SH had the most significant number of papers, and Ruetten S was cocited most often. <World Neurosurgery was the journal with the most papers, and Spine was the most commonly cocited journal. Keywords were stratified into 4 clusters by VOSviewer software: cluster 1 (clinical outcomes of ED in the treatment of lumbar disc herniation); cluster 2 (surgical technique of percutaneous endoscopic lumbar discectomy); cluster 3 (clinical outcomes of ED in the treatment of lumbar spinal stenosis); and cluster 4 (clinical outcomes of percutaneous endoscopic cervical discectomy). Several topics including lateral recess stenosis, spinal stenosis, and reoperation were considered as the next hotspot in ED research.
    CONCLUSION: ED research has gained considerable attention over the last 2 decades. Our bibliometric findings illuminate the publication trends and research hotspots of the ED field, which may provide useful references for scholars and decision-makers interested in this field.
    Keywords:  Bibliometric; CiteSpace; Endoscopic discectomy; VOSviewer
    DOI:  https://doi.org/10.14245/ns.2244574.287
  5. Front Public Health. 2022 ;10 1019691
      Background: Osteoarthritis has the characteristics of degenerative changes in articular cartilage and secondary osteoporosis, and it is a common chronic irreversible joint disease. In addition to affecting articular cartilage, subchondral bone, joint capsule and synovial membrane also undergo pathological changes during the development of the disease. Multiple studies have revealed that patients with osteoarthritis were found to have a significantly increased risk of osteoporosis, which also contributes to the progression of osteoarthritis. However, in the current existing studies, we found that no scholars have used bibliometric analysis in the study of the relationship between osteoarthritis and osteoporosis. From the perspective of bibliometrics, this study summarizes in detail the degree of cooperation between countries, research institutions, authors, and related journals in the field of osteoarthritis and osteoporosis research and their respective influence. In this way, the evolution of knowledge structure, the change of research focus and the hot topics with research potential in the future can be further visualized and analyzed.Methods: Search the Web of Science core collection in Science Citation Index Expanded for articles and reviews of research on osteoarthritis and osteoporosis from 1998 to 2021. Bibliometric tools such as VOSviewer, CiteSpace, were be frequently used in our study. They are mainly used to analyze collaborations between countries, research institutions, and publication authors. Meantime, co-citation analysis of journals, co-occurrence analysis of keywords and subject categories will also be reflected in the study.
    Results: According to the search strategy, 1,078 publications were included during the period 1998-2021. And the number of annual publications on the relationship between osteoarthritis and osteoporosis is on the rise. The United States has achieved the most and contributed the most in this field and the Boston University was the most prolific institution. For the statistical analysis of published publications, Reginster JY had the highest number of publications, while Felson DT had the highest co-citation frequency. Respectively, Osteoarthritis And Cartilage was the most productive journal in this area of research. The keywords "inflammation," "expression," and "mesenchymal stem cells" may also be the development trend and research hotspot of the future research direction in this field.
    Conclusions: In our study, the relationship between osteoarthritis and osteoporosis was analyzed by using literature measurement. These analysis results can lead researchers to learn more directly about the trend in this area and provide guidance for determining popular research directions.
    Keywords:  CiteSpace; VOSviewer; bibliometric analysis; osteoarthritis; osteoporosis; visualization
    DOI:  https://doi.org/10.3389/fpubh.2022.1019691
  6. Front Cardiovasc Med. 2022 ;9 1054816
      Background: Blood-derived exosomes are involved in developing multiple pathological processes, with platelets being the most well-known source. Related studies have become an area of research with significant value and potential. However, no bibliometric studies in this field have yet been identified. We aimed to analyze the hotspots and academic trends of platelet exosome research through bibliometric visualization to actively grasp the research base in this field and track its developmental orientation.Methods: From 2000 to 2022, we screened all relevant publications on platelet exosome-related research from the Web of Science database, generated knowledge maps using VOSviewer and CiteSpace software, and analyzed research trends in the field.
    Results: A total of 722 articles were screened for inclusion based on the search strategy. The number of articles on exosome studies in platelets has expanded vastly. The USA and the People's Republic of China contributed substantially among 69 countries or regions. Amsterdam University and Semmelweis University are the research institutions with the most publications. The most studied and co-cited journals were the International Journal of Molecular Sciences and the Journal of Extracellular Vesicles. We identified 4,598 authors, with Nieuwland Rienk having the highest number of articles and Bruno Stefania having the most cited publications. Keywords of great interest include "thrombosis," "anti-inflammatory," "anti-apoptosis," "angiogenesis," "microparticles," "miRNAs," "stem cells," and "biomarkers," which are key research areas for future development.
    Conclusion: We used bibliometric and visualization methods to identify hotspots and trends in platelet exosome research. Platelet exosome research is widely expanding. Future research will most likely focus on "thrombosis," "anti-inflammatory," "anti-apoptosis," "angiogenesis," "microparticles," "miRNAs," "stem cells," and "biomarkers."
    Keywords:  CiteSpace; VOSviewer; bibliometrics; exosomes; platelets
    DOI:  https://doi.org/10.3389/fcvm.2022.1054816
  7. Environ Sci Pollut Res Int. 2023 Jan 06.
      Cobalt is a strategic and critical mineral whose demand is expected to grow rapidly. This study aims to provide a comprehensive summary of cobalt extraction and recovery research from 2012 to 2021 in the form of bibliometric analysis. The work was based on the Science Citation Index Expanded (Web of Science) and carried out using the InCites of Clarivate for bibliometric data analysis and the software VOSviewer for science mapping. By analyzing a dataset of 4967 publications, the most influential journals, countries, authors, institutions, and publications were identified, and the keyword co-occurrence networks were mapped. The China mainland produced the most publications, while the USA had the highest average number of citations per publication and the UK was the most collaborative with other countries. The keyword analysis shows that the research hotspots gradually shifted over time from early means and methods for determination of cobalt in solution to recovery of cobalt from spent lithium batteries, smelting slag, copper-cobalt ore, etc. The research will be focused on further improvement and optimization of the separation, extraction, and recovery processes of cobalt from spent batteries in recent and future years, and three approaches were promoted to facilitate economization and industrialization of the processes in this field.
    Keywords:  Bibliometric analysis; Cobalt; Extraction; Recovery; Spent batteries; VOSviewer
    DOI:  https://doi.org/10.1007/s11356-022-24727-6
  8. Pancreas. 2022 Sep 01. 51(8): 957-965
      OBJECTIVES: Bibliometric analysis has not comprehensively summarized studies of acute pancreatitis (AP)-associated intestinal diseases. This work aimed to evaluate cooperative networks of authors, countries, and institutions and explore the field's developing trends and hot topics.METHODS: Original articles and reviews of AP-associated intestinal diseases were obtained from the Web of Science Core Collection on October 11, 2021. VOSviewer and CiteSpace software were used to perform co-occurrence analyses for authors, countries, and institutions and detect the highest citation burst.
    RESULTS: A total of 1634 articles on the intestine associated with AP were identified. The United States, the University of Auckland, and Roland Andersson are the most influential country, research institute, and scholar, respectively. The World Journal of Gastroenterology (73 articles) has the highest number of publications, and Gastroenterology was the most co-cited journal. The top 5 key words are "acute pancreatitis," "bacterial translocation," "management," "gut," and "inflammatory bowel disease." We find that several emergent key words like "gut microbiota," "pathway," "gut barrier," "risk," and "oxidative stress" experienced a continuous and rapid development as new research directions.
    CONCLUSIONS: This bibliometric study summarizes current important perspectives and offers comprehensive guidance on the AP-associated intestinal diseases, which may help researchers choose the most appropriate research directions.
    DOI:  https://doi.org/10.1097/MPA.0000000000002140
  9. Front Immunol. 2022 ;13 1092575
      Background: Autophagy refers to the process in which cells wrap their damaged organelles or unwanted proteins into a double-membrane structure and direct them to lysosomes for degradation. Autophagy can regulate many lung diseases such as pulmonary hypertension, acute lung injury, and lung cancer. However, few bibliometric studies on autophagy are available. The aim of the present study was to clarify the role of autophagy in lung diseases by bibliometric analysis.Methods: Publications were retrieved from the 2012-2021 Science Citation Index Expanded of Web of Science Core Collection on 20 September 2022. Bibliometrix package in R software was used for data retrieval. VOSviewer and CiteSpace were used to visualize the research focus and trend regarding the effect of autophagy on lung disease.
    Results: A total of 4,522 original articles and reviews on autophagy in lung diseases published between 2012 and 2021 were identified. China had the largest number of published papers and citations, whereas the United States (US) ranked first in the H-index and G-index. Moreover, cooperation network analysis showed close cooperation between the US, China, and some European countries, and the top 10 affiliates were all from these countries and regions. Bibliometric analysis showed that "autophagy" and "apoptosis" were the keywords with the highest frequency. During the past decade, most studies were concerned with basic research on pathways related to the regulatory role of autophagy in the inhibition and attenuation of lung diseases.
    Conclusion: The study of autophagy in lung diseases is still in the development stage. The information published in these articles has helped researchers understand further the hot spots and development trends in the field more and learn about the collaboration network information regarding authors, countries, and institutions, as well as the paper citation correlation. More studies have been performed to gain deeper insights into the pathogenesis of autophagy by focusing on the links and effects between various diseases. More recently, research in this field has paid increasing attention to the function of autophagy in COVID-19-related lung diseases.
    Keywords:  VOSviewer; autophagy; bibliometrics; bibliometrix; citespace; lung
    DOI:  https://doi.org/10.3389/fimmu.2022.1092575
  10. Front Oncol. 2022 ;12 1037145
      Introduction: Over the past decade, several studies on the microvascular invasion (MVI) of hepatocellular carcinoma (HCC) have been published. However, they have not quantitatively analyzed the remarkable impact of MVI. Therefore, a more comprehensive understanding of the field is now needed. This study aims to analyze the evolution of HCC-MVI research and to systematically evaluate the scientific outputs using bibliometric citation analysis.Methods: A systematic search was conducted on the Web of Science Core Collection on 2 May 2022 to retrieve studies on HCC-MVI published between 2013 and 2022. Then, a bibliometric analysis of the publications was performed using CiteSpace, VOSviewer, and other visualization tools.
    Results: A total of 1,208 articles on HCC MVI were identified. Of these, China (n = 518) was the most prolific country, and Fudan University (n = 90) was the most notable institution. Furthermore, we observed that Lau Wan Yee participated in most studies (n = 26), and Frontiers in Oncology (IF2020:6.24) published the highest number of documents (n = 49) on this subject, with 138 publications. The paper "Bray F, 2018, CA-CANCER J CLIN, V68, P394" has the highest number of co-cited references, with 119 citations. In addition, the top three keywords were "survival", "recurrence", and "microvascular invasion". Moreover, the research hot spots and frontiers of HCC-MVI for the last 3 years included imaging characteristics and transarterial chemoembolization (TACE) therapy studies.
    Conclusions: This study comprehensively summarized the most significant HCC-MVI documents from past literature and highlighted key contributions made to the advancement of this subject and the advancement of this field over the past decade. The trend of MVI research will gradually shift from risk factors and prognosis studies to imaging characteristics and TACE therapy studies.
    Keywords:  bibliometric analysis; hepatocellular carcinoma; microvascular invasion; prognosis; treatment
    DOI:  https://doi.org/10.3389/fonc.2022.1037145
  11. Medicine (Baltimore). 2022 Dec 30. 101(52): e32599
      Lipidomics has shaped our knowledge of how lipids play a central role in cardiovascular diseases (CVD), whereas there is a lack of a summary of existing research findings. This study performed a bibliometric analysis of lipidomics research in cardiovascular medicine to reveal the core countries, institutions, key researchers, important references, major journals, research hotspots and frontiers in this field. From 2012 to 2021, a total of 761 articles were obtained from the Web of Science Core Collection database. There is a steady increase of publications yearly. The United States and China are on the top of the list regarding article output. The institutions with the most publications were the Baker Heart and Diabetes Institute, the Chinese Academy of Sciences and Harvard Medical School. Peter J Meikle was both the most published and most co-cited author. The major journal in this field is Journal of lipid research. Keyword co-occurrence analysis indicated that coronary heart disease, mass spectrometry, risk, fatty acid, and insulin resistance have become hot topics in this field and keyword burst detection suggests that metabolomics, activation, liver, low density lipoprotein are the frontiers of research in recent years. Collectively, lipidomics in CVD is still in its infancy with a steady increase yearly. More in-depth studies in this area are warranted in the future.
    DOI:  https://doi.org/10.1097/MD.0000000000032599
  12. Front Neurol. 2022 ;13 1015546
      Objectives: This study aims to review the documents on dysphagia, summarize the research direction, analyze the research hot spots and frontiers, report the research trends, and provide new ideas for future development in the field via CiteSpace.Methods: We retrieved articles on dysphagia published between 2012 and 2021 from the Web of Science Core Collection database. We downloaded the entire data and utilized CiteSpace version 5.8.R3 (64-bit) to analyze the number of publications annually, cited journals, countries, institutions, authors, cited authors, cited references, and keywords. We visualized the data with a knowledge map, collaborative network analysis, cluster analysis, and strongest citation burst analysis.
    Results: We obtained 14,007 papers with a continually increasing trend over time. The most productive country and institute in this field were the United States (4,308) and Northwestern University (236), respectively. Dysphagia (5,062) and Laryngoscope (2,812) were the most productive journals, Elizabeth Ward had the highest number of publications (84), and Logeman et al.'s article (centrality: 0.02) was the most referenced. The most common keywords were dysphagia, management, quality of life, deglutition disorder, diagnosis, aspiration, prevalence, children, outcome, and oropharyngeal dysphagia.
    Conclusion: This study analyzed the current literature on dysphagia via CiteSpace and identified its research hot spots and frontiers. The prevalent global trends in dysphagia research and the growing public awareness about healthcare and quality of life suggest that research on dysphagia will gain popularity with further breakthroughs.
    Keywords:  Web of Science; research trend; scientometric review; swallowing disorder; visualization
    DOI:  https://doi.org/10.3389/fneur.2022.1015546
  13. Jpn J Radiol. 2023 Jan 06.
      PURPOSE: Breast cancer is the most common malignant tumor in women. Radiotherapy (RT) is an important adjunctive therapy for breast cancer, but the current international research trend of RT in breast cancer treatment and management is unclear. This bibliometric analysis was conducted to investigate the current trends and hot topics in this area.MATERIALS AND METHODS: The Web of Science Core Collection (WoSCC; Clarivate) database was searched, VOSviewer 1.6.18 and CiteSpace 6.1.R2 software were employed for the quantitative and qualitative analysis.
    RESULTS: 12,268 publications were included in this bibliometric analysis. There was an increasing trend of publications and international collaborations in the topic. The United States and The University of Texas MD Anderson Cancer Center were the most productive countries and institutions, respectively. The analysis of journals showed researches focused on both basic and clinical medicine on breast cancer RT. Park Won published the most papers and Fisher B had the most co-citations. The most co-cited paper was published in the Lancet. Survival, risk, chemotherapy, mastectomy, and surgery were regarded as current research hotspots through the analysis of keywords.
    CONCLUSION: Through quantitative and qualitative bibliometric analyses, this study provides insights into the research trends and potential research hotspots on breast cancer RT.
    Keywords:  Bibliometric analysis; Breast cancer; Radiotherapy; Research trends
    DOI:  https://doi.org/10.1007/s11604-022-01383-x
  14. Front Psychol. 2022 ;13 901668
      Objective: This study applied the bibliometric method to analyze the hotspots and frontiers in the field of postpartum depression research from 2017 to 2021.Methods: A computer-based search for studies related to postpartum depression (PPD) was conducted in the Web of Science Core Collection from 2017 to 2021. Using CiteSpace 5.8. R3 visualization software, this paper analyzed the hot spots and frontiers of postpartum depression research from countries, institutions, authors, cited references and keywords, and drew corresponding knowledge maps.
    Results: A total of 3,789 articles were retrieved, and the annual publication volume showed a steady increase. The countries and institutions with the most publications were the United States and the University of Toronto, respectively. Cindylee Dennis was the most productive author. The most frequently cited and centrally cited articles were meta-analyses on risk factors associated with antenatal depression or anxiety and meta-analyses on the prevalence of antenatal or postnatal anxiety, respectively. The research hotspots in the field of postpartum depression in the past 5 years mainly focused on the risk factors for PPD, and the impact of the COVID-19 epidemic on PPD. Providing various aspects of social and family support to women with PPD may be a research trend in this field.
    Conclusion: This study provides a trend and frontier in the field of postpartum depression, and valuable information for researchers to find potential partners and partner countries, and a reference for future research topics and development directions.
    Keywords:  CiteSpace; bibliometric; postpartum depression; review; visualization
    DOI:  https://doi.org/10.3389/fpsyg.2022.901668
  15. Medicine (Baltimore). 2022 Dec 30. 101(52): e32392
      BACKGROUND: We selected authors from mainland China, Hong Kong, and Taiwan (CHT) to examine citation trends on articles and keywords. The existence of suitable temporal bar graphs (TBGs) for displaying citation trends is unknown. It is necessary to enhance the traditional TBGs to provide readers with more information about the citation trend. The purpose of this study was to propose an advanced TBG that can be applied to understand the most worth-reading articles by ophthalmology authors in the CHT.METHODS: Using the search engine of the Web of Science core collection, we conducted bibliometric analyses to examine the article citation trends of ophthalmology authors in CHT since 2013. A total of 6695 metadata was collected from articles and review articles. Using radar plots, the Y-index, and the combining the Y-index with the CJAL scores (CJAL) scores, we could determine the dominance of publications by year, region, institute, journal, department, and author. A choropleth map, a dot plot, and a 4-quadrant radar plot were used to visualize the results. A TBG was designed and provided for readers to display citation trends on articles and keywords.
    RESULTS: We found that the majority of publications were published in 2017 (2275), Shanghai city (935), Sun Yat-Sen University (China) (689), the international journal Ophthalmology (1399), the Department of Ophthalmology (3035), and the author Peizeng Yang (Chongqing) (65); the highest CAJL scores were also from Guangdong (2767.22), Sun Yat-Sen University (China) (2147.35), and the Ophthalmology Department (7130.96); the author Peizeng Yang (Chongqing) (170.16) had the highest CAJL; and the enhanced TBG features maximum counts and recent growth trends that are not included in traditional TBGs.
    CONCLUSION: Using the Y-index and the CJAL score compared with research achievements of ophthalmology authors in CHT, a 4-quadrant radar plot was provided. The enhanced TBGs and the CJAL scores are recommended for future bibliographical studies.
    DOI:  https://doi.org/10.1097/MD.0000000000032392
  16. Front Immunol. 2022 ;13 1096806
      Background: Despite providing clinical benefit, immune checkpoint inhibitors (ICIs) can cause immune-related adverse events (irAEs) in a number of patients. This study explored the development pattern in irAEs research from a bibliometric perspective.Methods: We obtained articles and reviews related to irAEs from the Web of Science Core Collection (WoSCC) (retrieved on September 13, 2022). Using the R package "Bibliometrix", the main bibliometric features were calculated, and a three-filed plot was generated to show the relationship between authors, institutions, and topics. VOSviewer was used for co-authorship and keyword co-occurrence analysis and visualization. CiteSpace was used to detect burst references and keywords.
    Results: A total of 3995 publications on irAEs were included. The United States (US), Japan, and China had the highest publications. The Journal for ImmunoTherapy of Cancer had the highest number of publications. In addition to "immune-related adverse events", "immune checkpoint inhibitors", "immunotherapy", and "nivolumab" were the most frequently used keywords.
    Conclusions: A bibliometric analysis of 17 years of irAEs research was conducted to map a basic knowledge structure including countries, institutions, authors, journals, and publications. The findings provided a comprehensive perspective on the broad future of this research area.
    Keywords:  VOSviewer; bibliometrics; citespace; frontiers; immune-related adverse events
    DOI:  https://doi.org/10.3389/fimmu.2022.1096806
  17. Pain Physician. 2022 Dec;25(9): E1433-E1445
      BACKGROUND: Ultrasound imaging is shown to be superior to other imaging tools for the evaluation of shoulder disorders in a primary care settings. In addition to its diagnostic utility, ultrasound diathermy is useful as a deep heat modality for the management of shoulder pain.OBJECTIVE AND STUDY DESIGN: In this study, we analyzed the bibliometric data of publications that have focused on ultrasound imaging/therapy for shoulder-related pain syndrome.
    METHODS: We searched the Web of Science (WoS) database for articles published between January 1, 1976, and June 24, 2022. The CiteSpace Version 6.1R2 software was used to analyze publication output, authoritative journals/countries/institutions/authors, keywords, references, and citations.
    RESULTS: We analyzed 1185 articles in this study and observed a significant trend of an increase in publications per year (beta coefficient 1.8165, R2 = 0.7519, P < 0.001). The maximum number of relevant citations was identified in 2009, and these declined in subsequent years. The Journal of Ultrasound in Medicine, the United States of America, and the League of European Research Universities were identified as the journal, country, and institution with the highest number of publications, respectively. Keyword analysis revealed that "ultrasonography" showed the strongest citation bursts, followed by "arthroscopic findings" and "painful shoulders."
    LIMITATIONS: We only analyzed publications indexed in the WoS because most indicators required for bibliometric analysis can be efficiently extracted from its website.
    CONCLUSION: This study highlights a significant trend of an increase in the number of publications focused on ultrasound imaging for shoulder-related pain syndrome. Ultrasound was shown to be a highly popular imaging modality among health care practitioners for the evaluation of shoulder disorders. Randomized controlled trials and state-of-the-art reviews are warranted to boost the citation count and conclusively establish the role of ultrasound applications in patients with shoulder pain syndrome.
    Keywords:   imaging; pain; shoulder; ultrasonography ; Bibliometric
  18. Front Microbiol. 2022 ;13 1018594
      Background: There are trillions of microbiota in our intestinal tract, and they play a significant role in health and disease via interacting with the host in metabolic, immune, neural, and endocrine pathways. Over the past decades, numerous studies have been published in the field of gut microbiome and disease. Although there are narrative reviews of gut microbiome and certain diseases, the whole field is lack of systematic and quantitative analysis. Therefore, we outline research status of the gut microbiome and disease, and present insights into developments and characteristics of this field to provide a holistic grasp and future research directions.Methods: An advanced search was carried out in the Web of Science Core Collection (WoSCC), basing on the term "gut microbiome" and its synonyms. The current status and developing trends of this scientific domain were evaluated by bibliometric methodology. CiteSpace was used to perform collaboration network analysis, co-citation analysis and citation burst detection.
    Results: A total of 29,870 articles and 13,311 reviews were retrieved from the database, which involve 42,900 keywords, 176 countries/regions, 19,065 institutions, 147,225 authors and 4,251 journals. The gut microbiome and disease research is active and has received increasing attention. Co-cited reference analysis revealed the landmark articles in the field. The United States had the largest number of publications and close cooperation with other countries. The current research mainly focuses on gastrointestinal diseases, such as inflammatory bowel disease (IBD), ulcerative colitis (UC) and Crohn's disease (CD), while extra-intestinal diseases are also rising, such as obesity, diabetes, cardiovascular disease, Alzheimer's disease, Parkinson's disease. Omics technologies, fecal microbiota transplantation (FMT) and metabolites linked to mechanism would be more concerned in the future.
    Conclusion: The gut microbiome and disease has been a booming field of research, and the trend is expected to continue. Overall, this research field shows a multitude of challenges and great opportunities.
    Keywords:  gut microbiota; hot topics and frontiers; human health and disease; research trend; visualized analysis
    DOI:  https://doi.org/10.3389/fmicb.2022.1018594
  19. Front Oncol. 2022 ;12 1068805
      Background: As a processing method of RNA precursors, alternative splicing (AS) is critical to normal cellular activities. Aberrant AS events are associated with cancer development and can be promising targets to treat cancer. However, no detailed and unbiased study describes the current state of AS of cancer research. We aim to measure and recognize the current state and trends of AS cancer research in this study.Methods: The Web of Science Core Collection was used to acquire the articles. Utilizing three bibliometric tools (CiteSpace, VOSviewer, R-bibliometrix), we were able to measure and recognize the influence and collaboration data of individual articles, journals, and co-citations. Analysis of co-occurrence and burst information helped us identify the trending research areas related to AS of cancer.
    Results: From 2012 to 2021, the total number of papers on AS of cancer published in 766 academic journals was 3,507, authored by 20,406 researchers in 405 institutions from 80 countries/regions. Research involving AS of cancer genes was primarily conducted in the United States and China; simultaneously, the Chinese Academy of Sciences, Fudan University, and National Cancer Institute were the institutions with strong research capabilities. Scorilas Andreas is the scholar with the most publications, while the most co-citations were generated by Wang, Eric T. Plos One published the most papers on AS of cancer, while J Biol Chem was the most co-cited academic journal in this field. The results of keyword co-occurrence analysis can be divided into three types: molecular (P53, CD44, androgen receptor, srsf3, esrp1), pathological process (apoptosis, EMT, metastasis, angiogenesis, proliferation), and disease (breast cancer, colorectal cancer, prostate cancer, hepatocellular carcinoma, gastric cancer).
    Conclusion: Research on AS of cancer has been increasing in intensity over the past decade. Current AS of cancer studies focused on the hallmarks of AS in cancer and AS signatures including diagnostic and therapeutic targets. Among them, the current trends are splicing factors regulating epithelial-mesenchymal transition and other hallmarks, aberrant splicing events in tumors, and further mechanisms. These might give researchers interested in this field a forward-looking perspective and inform further research.
    Keywords:  CiteSpace; R-bibliometrix; VOSviewer; alternative splicing; bibliometric; cancer
    DOI:  https://doi.org/10.3389/fonc.2022.1068805
  20. J Cutan Pathol. 2023 Jan 06.
      BACKGROUND: Both Dermatopathology and Dermatology are highly visual medical specialties. We performed a bibliometric literature survey of the visual arts in reference to either discipline to better understand how medical literature approaches art within the context of the two specialties.MATERIALS AND METHODS: We performed a bibliometric analysis of publications found via multiple medical search engines and selected keywords meant to capture art-related publications in dermatopathology and dermatology. Keywords (art, portrait, painting, dermatology, dermatopathology, etc.) and keyword combinations were entered into the search engines PubMed, Google Scholar, Science Direct, Pubs Hub, and Scopus. Topics of articles, years of publication, countries of origin, and contributing journals were compiled and analyzed.
    RESULTS: 80 publications were retrieved between January 1903 and August 2021. The highest number of articles were found in both PubMed and Google Scholar (n=55), and the top publication year was 2020 (n =11). Geographically, the United States of America (n=38) had the greatest number of articles. The dermatology and art keyword combination yielded the most journal articles (n=36), and the maximum number of publications were retrieved from JAMA Dermatology (n= 14) followed by the American Journal of Dermatopathology (AJDP) (n=10).
    CONCLUSION: Our survey showed an increasing number of publications related to the visual arts and dermatopathology/dermatology during the examined period, and a transition from observational case studies (often relating to art history) to articles examining the incorporation of the visual arts into medical training programs or professional societies.
    Keywords:  art; dermatology; dermatopathology; diagram; images; pathology; pictures; portraits; sculpture; skin
    DOI:  https://doi.org/10.1111/cup.14382
  21. Glob Ment Health (Camb). 2022 ;9 366-374
      Background: The COVID-19 pandemic has captured the mental health discussion worldwide. Examining countries' representation in this discussion could prove instrumental in identifying potential gaps in terms of ensuring a truly global conversation in times of global crisis.Methods: We collected mental health and COVID-19-related journal articles published in PubMed in 2020. We focused on the corresponding authors' countries of affiliation to explore countries' representation. We also examined these articles' academic impact and correlations with their corresponding authors' countries of affiliation. Additional journals and countries' indicators were collected from the Web of Science and World Bank websites, respectively. Data were analyzed using the IBM SPSS Statistics and the VOSviewer software.
    Results: In total, 3492 publications were analyzed. Based on the corresponding author, high-income countries produced 61.9% of these publications. Corresponding authors from Africa, Latin America and the Caribbean, and the Middle East combined accounted for 11.8% of the publications. Europe hosted corresponding authors with the most publications and citations, and corresponding authors from North America had the largest mean journal impact factor.
    Conclusions: The global scientific discussion during the COVID-19 pandemic saw an increased contribution of academics from developing countries. However, authors from high-income countries have continued to shape this discussion. It is imperative to ensure the active participation of low- and middle-income countries in setting up the global mental health research agenda, particularly in situations of global crisis, such as the ongoing pandemic.
    Keywords:  Bibliometrics; PubMed; global health; mental health; publishing
    DOI:  https://doi.org/10.1017/gmh.2022.37
  22. Front Psychol. 2022 ;13 1009216
      As a result of the trend toward economic globalization, the vigorous development of cross-border e-commerce has attracted many scholars to study this field, involving many related fields, such as consumer behavior, advertising, information systems, and supply chain management. Throughout the existing literature, it can be found that most of the research focuses on certain influencing factors of the development of cross-border e-commerce, and there is no systematic and macro- overview of the development trend of research in this field in recent years, nor the integration and analysis of keywords. Given that the research in the field of cross-border e-commerce is fragmented to a large extent, to effectively explore the research trend in this field, we must understand the current situation of cross-border e-commerce. Systematic bibliometric analysis can solve this problem by providing publishing trends and information on various topics. Therefore, based on the scientific database web, this study collected 198 references related to cross-border e-commerce from 2016 to 2021, briefly introduced the current situation and development trend of cross-border e-commerce, visually analyzed and refined the journals, authors, research institutions, countries, publication years, keywords, citations of academic publications in this field, and other key information, and summarized the development trend and path of CEBC in the existing research. It is helpful for researchers to solve the current research gap, understand the future research direction in this field, and help academia establish a strict knowledge system.
    Keywords:  bibliometric analysis; cross-border e-commerce; knowledge graph; mixed research; trend of development
    DOI:  https://doi.org/10.3389/fpsyg.2022.1009216
  23. Clin Rheumatol. 2023 Jan 05.
      BACKGROUND: Antiphospholipid syndrome is an autoimmune disorder characterized by recurrent vascular thrombosis and pregnancy losses in the presence of persistently positive antiphospholipid antibodies. Bibliometric analysis and altmetric analysis are methods of analyzing academic productivity and influence. Currently, the assessment of antiphospholipid syndrome through the above analyses is lacking. This study investigated the quantity and quality of studies in the field of antiphospholipid syndrome and revealed the characteristics of worldwide productivity on this disease by the bibliometric analysis and altmetric analysis.METHODS: The terms "APS," "antiphospholipid syndrome," "antiphospholipid-antibody syndrome," and "Hughes syndrome" were searched on the Web of Science Core Collection from January 1, 2011, to December 31, 2021. Original articles and reviews were selected. We set the filters as "English."
    RESULTS AND CONCLUSION: A total of 1818 articles were retrieved from 68 countries, of which 20 met the criteria of major active countries. High-income countries contributed 1341 articles (73.48%). The number of articles annually increased significantly in the 10-year period (P < 0.001). The USA (253, 13.91%) was the most productive country. Adjusted by population, Serbia was top of the list. According to the gross domestic product analysis, Serbia ranked first. The most used keywords such as thrombosis and antiphospholipid antibodies were presented by keywords analyses. A content analysis found antithrombotic and anticoagulant therapy as research hotspots. A significant correlation was detected between average citations and altmetric attention scores (P = 0.002) and Mendeley readers count (P < 0.001). From 2011 to 2021, the number of global articles increased rapidly. Most papers came from high-income countries. The relationship between the bibliometric and altmetric analyses were basically consistent; therefore the two can prove/complement each other. Key points • We revealed the global productivity characteristics of the papers related to antiphospholipid syndrome by using the methods of bibliometric analysis and altmetric analysis. • We found the most selected articles that describe the treatment of antiphospholipid syndrome, especially antithrombotic and anticoagulant treatments, which may be the current research hotspot.
    Keywords:  Altmetric attention scores; Antiphospholipid syndrome; Antiphospholipid-antibody syndrome; Bibliometric analysis; Web of Science
    DOI:  https://doi.org/10.1007/s10067-022-06485-5
  24. Front Pharmacol. 2022 ;13 1062249
      Background: Lecithin cholesterol acyltransferase (LCAT) is an important enzyme responsible for free cholesterol (FC) esterification, which is critical for high density lipoprotein (HDL) maturation and the completion of the reverse cholesterol transport (RCT) process. Plasma LCAT activity and concentration showed various patterns under different physiological and pathological conditions. Research on LCAT has grown rapidly over the past 50 years, but there are no bibliometric studies summarizing this field as a whole. This study aimed to use the bibliometric analysis to demonstrate the trends in LCAT publications, thus offering a brief perspective with regard to future developments in this field. Methods: We used the Web of Science Core Collection to retrieve LCAT-related studies published from 1975 to 2020. The data were further analyzed in the number of studies, the journal which published the most LCAT-related studies, co-authorship network, co-country network, co-institute network, co-reference and the keywords burst by CiteSpace V 5.7. Results: 2584 publications contained 55,311 references were used to analyzed. The number of included articles fluctuated in each year. We found that Journal of lipid research published the most LCAT-related studies. Among all the authors who work on LCAT, they tend to collaborate with a relatively stable group of collaborators to generate several major authors clusters which Albers, J. published the most studies (n = 53). The United States of America contributed the greatest proportion (n = 1036) of LCAT-related studies. The LCAT-related studies have been focused on the vascular disease, lecithin-cholesterol acyltransferase reaction, phospholipid, cholesterol efflux, chronic kidney disease, milk fever, nephrotic syndrome, platelet-activating factor acetylhydrolase, reconstituted lpa-i, reverse cholesterol transport. Four main research frontiers in terms of burst strength for LCAT-related studies including "transgenic mice", "oxidative stress", "risk", and "cholesterol metabolism "need more attention. Conclusion: This is the first study that demonstrated the trends and future development in LCAT publications. Further studies should focus on the accurate metabolic process of LCAT dependent or independent of RCT using metabolic marker tracking techniques. It was also well worth to further studying the possibility that LCAT may qualify as a biomarker for risk prediction and clinical treatment.
    Keywords:  bibliometrics; emerging trends; lecithin cholesterol acyltransferase; physiological; risk
    DOI:  https://doi.org/10.3389/fphar.2022.1062249
  25. Adv Radiat Oncol. 2023 Mar-Apr;8(2):8(2): 101135
      Purpose: It is well-documented that gender disparities exist in academic radiation oncology departments. The purpose of this study was to analyze gender differences in research productivity during residency among recent graduates of radiation oncology training programs in the United States (US).Methods and Materials: We used several publicly available sources to create a database of US radiation oncology residents who graduated between 2015 and 2019. We systematically collected gender information from the National Plan and Provider Enumeration System National Provider Identifier Registry and Medicare claims registry. Postresidency employment information was collected using several publicly available sources. PubMed was queried to identify first-author publications of residents. A secondary analysis of metadata including impact factor, number of citations, modified Hirsch index (h index), and type of publication was performed. A multivariable linear regression was performed to evaluate the effect of gender on research productivity during residency.
    Results: There were 910 total graduates identified during this period and who were entered into this database, of whom all had available gender information. Female trainees comprised 29.0% (n = 264) of RO residents and had fewer first-author publications and citations, had lower mean modified h index, and were published in journals with lower impact factors. On multivariable linear regression analysis, female gender was independently associated with decreased total number of publications (P = .005), mean number of citations (P < .001), and modified h index (P = .001) when controlling for residency size and advanced (PhD or master's) degrees.
    Conclusions: In the US, female RO trainees had lower research productivity, which was not explained by advanced degrees or residency size. A significant gender gap in trainee research productivity persists, which has known implications in terms of academic achievement, promotions, and career trajectory. Future interventions to improve resident research productivity and mentorship are warranted.
    DOI:  https://doi.org/10.1016/j.adro.2022.101135
  26. J Vasc Surg. 2023 Jan 02. pii: S0741-5214(22)02717-3. [Epub ahead of print]
      OBJECTIVE: The demand for vascular surgeons in the United States (US) stands to far exceed the current supply. International Medical Graduates (IMGs) are not only vital to meeting the country's growing healthcare needs, but also help to advance clinical research and medical education in the field of vascular surgery. Nearly 17% of practicing vascular surgeons in the U.S. are IMGs, yet little is known about their relative contributions to academic vascular surgery. Our study aims to compare the academic profiles and funding support for IMG vascular surgeons to that of their US medical graduate (USMG) counterparts.METHODS: A cross-sectional study was performed on all IMG and USMG academic vascular surgeons practicing in U.S.-based hospitals with vascular surgery residency and/or fellowship programs. In addition to the baseline surgeon characteristics, academic profiles and research output were also collected. Furthermore, the National Institutes of Health (NIH) research reporting tool and open payments database were queried for any funding/payments to surgeons in both groups. Matching for year of vascular surgery training program graduation was performed where appropriate.
    RESULTS: A total of 908 academic vascular surgeons were included, 759 (83.6%) were USMGs, while 149 (16.4%) were IMGs. The median year of graduation was comparable between the two groups, but USMGs had a significantly higher proportion of female surgeons (23.6% vs. 10.7%; P = .0003). There were no significant differences in the academic profiles and leadership positions between the two groups. While research productivity is similar between the two groups, IMG surgeons were more likely to have first or senior-authorship papers (47.1% vs. 37.5%; P<.001). Additionally, faculty departments chaired/cheifed by a USMG were less likely to be staffed with IMG vascular surgeons (1.6 vs. 3.1 surgeons; P<.0001). Following grant analysis, USMG surgeons were more likely to receive NIH R01 grants (5.7% vs. 1.3%; P=.026). R01-funded surgeons had significantly greater research output by number of publications (121 vs. 47.5), citations (3872 vs. 938), H-index (32 vs. 17.5) and average journal impact factor (Journal IF>10: 86.7% vs. 33.3%) (all P<.001).
    CONCLUSIONS: The efforts to further diversify vascular surgery are vital to better serving an increasingly diverse US population, amidst growing disparities in healthcare. Though IMGs account for a minority of academic vascular surgeons, and they contribute significantly to published research, they are less likely to receive NIH R01 funding, warranting further investigation.
    Keywords:  IMG; r01 grant; research productivity; vascular surgeons
    DOI:  https://doi.org/10.1016/j.jvs.2022.12.038
  27. J Surg Orthop Adv. 2022 ;31(4): 263-267
      The purpose of this study is to investigate the association between Hirsch index (h-index) and academic rank among foot and ankle surgeons affiliated with American Orthopaedic Foot and Ankle Society (AOFAS) fellowship programs. The total number of publications, academic rank, years in practice, fellowship training pedigree, and h-indices of 176 foot and ankle surgeons from 48 AOFAS fellowship programs were recorded, and statistical analysis was performed. We found a strong association between total number of publications and h-index. Number of publications, h-index and training program affiliation were associated with higher academic rank, except at the chair/director position. Overall, h-index is a stronger predictor of academic rank than number of publications. The results of this study suggest that h-index and total number of publications are associated with a higher academic rank for full-time foot and ankle fellowship affiliated surgeons. (Journal of Surgical Orthopaedic Advances 31(4):263-267, 2022).
  28. Front Endocrinol (Lausanne). 2022 ;13 963213
      Introduction: To map publication trends and explore research hotspots of insulin resistance (IR) in polycystic ovary syndrome (PCOS) study.Methods: With the theme of "Polycystic ovary syndrome" AND "Insulin Resistance", the key data set of Science Core Literature Collection (WoSCC) web from 2017 to 2021 was extracted and bibliometric analysis was performed. Through VOSviewer v1.6.10 software, the research trend in this field is analyzed visually.
    Results: 2080 literatures about IR in PCOS from 2017 to 2021 were downloaded. The following basic information was collected for each article: country, author, institution, journal, references. The key words are divided into six categories: (1) The interaction between insulin resistance and chronic inflammation; (2) The relationship between insulin resistance and metabolic syndrome and nonalcoholic fatty liver disease; (3) The interaction between insulin resistance and hyperandrogenemia; (4) The relationship between insulin resistance and dyslipidemia; (5) Metformin may regulate insulin resistance in the treatment of PCOS; (6) The study of serum biomarkers in PCOS patients with insulin resistance.
    Discussion: The six key words extracted can provide an in-depth perspective for the study of IR in PCOS, and provide valuable information to help researchers identify potential research directions, collaborators and cooperative institutions.
    Keywords:  VOSviewer; bibliometrics; insulin resistance; polycystic ovary syndrome; visual analysis
    DOI:  https://doi.org/10.3389/fendo.2022.963213
  29. Chemosphere. 2022 Dec 28. pii: S0045-6535(22)04171-6. [Epub ahead of print]314 137678
      Desulfurization wastewater in coal-fired power plants (CFPPs) is a great environmental challenge. This study aimed at the current status and future research trends of desulfurization wastewater by bibliometric analysis. The desulfurization wastewater featured with high sulfate (8000 mg/L), chlorite (8505 mg/L), magnesium (2882 mg/L) and calcium (969 mg/L) but low sodium (801.82 mg/L), and the concentrations of the main contaminants were critically summarized. There was an increasing trend in the annual publications of desulfurization wastewater in the period from 1991 to 2021, with an average growth rate of 15%. Water Science and Technology, Desalination and Water Treatment, Energy & Fuels, Chemosphere, and Journal of Hazardous Materials are the top 5 journals in this field. China was the most productive country (58.3% of global output) and the core country in the international cooperation network. Wordcloud analysis and keyword topic trend demonstrated that removal/treatment of pollutants dominated the global research in the field of desulfurization wastewater. The primary technologies for desulfurization wastewater treatment were systematically evaluated. The physicochemical treatment technologies occupied half of the total treatment methods, while membrane-based integrated processes showed potential applications for beneficial reuse. The challenges and outlook on desulfurization wastewater treatment for achieving zero liquid discharge are summarized.
    Keywords:  Bibliometric analysis; Co-occurrence; Desulfurization wastewater; Wastewater quality; Zero liquid discharge
    DOI:  https://doi.org/10.1016/j.chemosphere.2022.137678
  30. Evid Based Complement Alternat Med. 2022 ;2022 3971967
      Background: Marine traditional Chinese medicine (MTCM) is a class of traditional medicine that has antitumor, anti-inflammatory, and antiviral properties. Bibliometric approaches were used in this study to conduct systematic research in order to gain a complete picture of MTCM research around the world.Methods: CiteSpace and NoteExpress software were utilized as tools to examine the information about authors, sources, keywords, etc. Chinese publications were collected from the CNKI, VIP, and WANFANG databases; English publications were collected from the Web of Science database.
    Results: A total of 10080 publications were screened, and the search volume of Chinese literature is greater than that of English literature; Nanjing University of Chinese Medicine, China, and Jeju National University, South Korea, published a greater number of articles than other institutions; the scholars Zhaohui-Zhang and Youjin-Jeon have published the highest number of articles in the world. MTCM of shells was often researched for inorganic elements, and data mining methods were applied frequently; MTCM of animals was commonly used for antifatigue and was taken authenticity identification owing to the scarcity of resources; scholars conducted the most research on MTCM of plants, this category usually for antitumor, anti-inflammatory, and antioxidant purposes, and the mechanisms of action were studied in depth. The Chinese literature has undertaken a multifaceted research study based on the theories of processing and the nature of TCM. In the English literature, in-depth studies have been done from the perspectives of the mechanism of action, the extraction and purification of active substances, etc.
    Conclusions: According to the analysis of keywords, different medicinal parts present their own special research directions, and different research hotspots have also emerged under different medical theories. The development of MTCM is moving in the direction of standardization and modernization, thanks to the development of cross-disciplinary research as well as the use of several new technologies and statistical techniques.
    DOI:  https://doi.org/10.1155/2022/3971967
  31. J Surg Orthop Adv. 2022 ;31(4): 205-208
      This study aims to evaluate the research productivity trends in orthopaedic residents who were selected for shoulder and elbow fellowships from 2010 to 2019. We hypothesize that residents matching into orthopaedic shoulder and elbow fellowships are increasing both their publication number and publication quality from 2010 to 2019. Fellows of orthopaedic shoulder and elbow programs from 2010 to 2019 were identified through publicly accessible information on fellowship programs. Each fellow's publication data during their residency was collected via publicly available search engines, and analyzed to include: fellowship year, residency years, fellowship program and location, total publications, number of publications in high-impact general orthopaedic and shoulder and elbow journals, and authorship position. A total of 176 orthopaedic shoulder and elbow fellows from 17 different programs were identified and included in the study. The fellows produced a total of 668 publications, published 172 articles in high impact journals, and had first authorship on 49% of the studies. On average, there were 3.8 publications per fellow per year from 2010 to 2019. There were 5.7 publications produced per fellow in 2018-2019, compared to just 2.92 publications per fellow in 2010-2011. Overall, there was an increasing trend in publications, publications in high impact journals, and first authorship publications per applicant matching into shoulder and elbow fellowship from 2010 to 2019. (Journal of Surgical Orthopaedic Advances 31(4):205-208, 2022).
  32. Res Dev Disabil. 2022 Dec 30. pii: S0891-4222(22)00225-6. [Epub ahead of print]133 104395
      BACKGROUND: Developmental disabilities are disproportionately more investigated in higher-income countries. However, global prevalence of developmental disabilities indicate that a large proportion of individuals with disabilities reside in low- and middle-income nations.AIMS: The present work therefore aims to conduct a scientometric review to survey available literature on developmental disabilities in low- and middle-income countries belonging to the continent of Africa.
    METHODS AND PROCEDURES: A literature search was conducted on Scopus, where a total of 1720 relevant publications (and an accompanying 66 thousand references) were found, representing research conducted between 1950 to 2022. Then, document co-citation analysis was performed to chart significant co-citation relationships between relevant articles and their cited references.
    OUTCOMES AND RESULTS: The generated network based on document co-citation analysis revealed a total of 14 distinct thematic research clusters and 12 significant documents that have been frequently cited in the literature on developmental disabilities in Africa.
    CONCLUSIONS AND IMPLICATIONS: The scientometric review revealed a trend of broadening research towards systems of care, away from a medical model of disease. It is projected that future research will continue to capitalise on inter-disciplinary strengths to arrive at a more nuanced understanding of developmental disability from all levels - individuals, families, to communities.
    Keywords:  Africa; Autism; CiteSpace; Developmental disabilities; Document co-citation analysis; Low- and middle-income countries
    DOI:  https://doi.org/10.1016/j.ridd.2022.104395
  33. PLoS One. 2023 ;18(1): e0279314
      Scientific literature, as the major medium that carries knowledge between scientists, exhibits explosive growth in the last century. Despite the frequent use of many tangible measures, to quantify the influence of literature from different perspectives, it remains unclear how knowledge is embodied and measured among tremendous scientific productivity, as knowledge underlying scientific literature is abstract and difficult to concretize. In this regard, there has laid a vacancy in the theoretical embodiment of knowledge for their evaluation and excavation. Here, for the first time, we quantify the knowledge from the perspective of information structurization and define a new measure of knowledge quantification index (KQI) that leverages the extent of disorder difference caused by hierarchical structure in the citation network to represent knowledge production in the literature. Built upon 214 million articles, published from 1800 to 2021, KQI is demonstrated for mining influential classics and laureates that are omitted by traditional metrics, thanks to in-depth utilization of structure. Due to the additivity of entropy and the interconnectivity of the network, KQI assembles numerous scientific impact metrics into one and gains interpretability and resistance to manipulation. In addition, KQI explores a new perspective regarding knowledge measurement through entropy and structure, utilizing structure rather than semantics to avoid ambiguity and attain applicability.
    DOI:  https://doi.org/10.1371/journal.pone.0279314
  34. Medicine (Baltimore). 2022 Dec 23. 101(51): e32400
      Very low proportions of publications from low- and middle-income countries (LAMIC) have been proved in multiple fields. Some researchers from these countries believe that there is a biased attitude of editors against their studies. Under-representation of editorial board members from LAMIC were revealed in many research fields. However, it has not been investigated in the field of foot and ankle surgery. The current study aimed to analyze the composition of the editorial board members in leading foot and ankle journals, and to provide the international representation of editorial boards in the field of foot and ankle surgery. Five leading journals in the field of foot and ankle surgery were included. The editorial board members were collected from the official websites of these journals. The countries of board members were classified based on World Bank. The board compositions of the journals were analyzed. In total, 229 editorial board members were identified. These editors were from 29 countries. The United States (29.69%) had the greatest number of editors, followed by the United Kingdom (20.52%), Australia (8.30%), Italy (6.11%), and Germany (5.68%). When the editors were classified by regions, 49.34% of board members were from Europe & Central Asia, followed by North America (31.44%), East Asia & Pacific (14.41%), Latin America & Caribbean (2.62%), and Middle East & North Africa (2.18%). No editors were from South Asia and Sub-Saharan Africa. A total of 217 editors (94.76%) were from high-income countries, followed by upper-middle-income countries (3.06%), and lower-middle-income countries (2.18%). No members were from low-income countries. There is a lack of international representation on editorial boards of leading foot and ankle journals. Editorial board members in the field of foot and ankle surgery are largely composed by editors from high-income countries with sever under-representation of LAMIC.
    DOI:  https://doi.org/10.1097/MD.0000000000032400
  35. J Speech Lang Hear Res. 2023 Jan 04. 1-10
      PURPOSE: This study examined the effect of open access (OA) status on scholarly and societal metrics of impact (citation counts and altmetric scores, respectively) across manuscripts published in the American Speech-Language-Hearing Association (ASHA) Journals.METHOD: Three thousand four hundred nineteen manuscripts published in four active ASHA Journals were grouped across three access statuses based on their availability to the public: Gold OA, Green OA, and Closed Access. Two linear mixed-effects models tested the effects of OA status on citation counts and altmetric scores of the manuscripts.
    RESULTS: Both Green OA and Gold OA significantly predicted a 2.70 and 5.21 respective increase in citation counts compared with Closed Access manuscripts (p < .001). Gold OA was estimated to predict a 25.7-point significant increase in altmetric scores (p < .001), but Green OA was only marginally significant (p = .68) in predicting a 1.44 increase in altmetric scores relative to Closed Access manuscripts.
    DISCUSSION: Communication sciences and disorders (CSD) research that is fully open receives more online attention and, overall, more scientific attention than research that is paywalled or available through Green OA methods. Additional research is needed to understand secondary variables affecting these and other scholarly and societal metrics of impact across studies in CSD. Ongoing support and incentives to reduce the inequities of OA publishing are critical for continued scientific advancement. Open Science Form: https://doi.org/10.23641/asha.21766919.
    DOI:  https://doi.org/10.1044/2022_JSLHR-22-00315
  36. Women Health. 2023 Jan 02. 1-7
      Despite efforts toward equity, diversity, and inclusion in academic ophthalmology faculties, gender disparity continues to exist. Current evidence indicates that female ophthalmologists consistently hold lower academic ranks and receive less funding from the National Institutes of Health compared to their male colleagues. The extent of this disparity is unknown in the Canadian context. We sought to characterize the gender gap in Canadian Institutes of Health Research funding among ophthalmologists. From inception, funding decision data were collected from the official Canadian Institutes of Health Research website database hosted by the Government of Canada. Measures including gender, number of grants held over the study period, number of simultaneous grants, and total funding were collected. Female ophthalmologists were consistently awarded fewer grants (21.43 percent) compared to male counterparts and were less likely to hold multiple grants since 2008. An over five-fold disparity was found in total funding for female compared to male ophthalmologists. As well, females were less likely than males to hold a grant in each particular year except in 2020. Female ophthalmologists continue to face barriers to attaining academic support from Canadian Institute of Health Research funds. Continued action to mitigate this gender gap may improve gender-based parity in federal research funding.
    Keywords:  CIHR; equity; funding; gender; ophthalmology
    DOI:  https://doi.org/10.1080/03630242.2022.2164113
  37. World J Surg. 2023 Jan 01.
      BACKGROUND: Inequitable representation in journal editorial boards may impact women's career progression across surgical, anesthesia, and obstetric (SAO) specialties. However, data from Latin America are lacking. We evaluated women's representation on editorial boards of Latin America SAO journals in 2021.METHODS: We conducted a cross-sectional analysis, retrieving journals through Scimago Journal and Country Rank 2020. Journals were included if active, focused on SAO topics, and publicly provided information on editorial board staff. Editorial board member names and positions were extracted from journals' websites. Members were classified into senior (e.g., editor-in-chief), academic (e.g., reviewer), and non-academic roles (e.g., administrative office). Women's representation was predicted from first names using Genderize.io. The number of women SAO physicians per country was obtained from articles and governmental reports.
    RESULTS: We included 19 of 25 identified journals and analyzed 1,318 names. Three anesthesiology, seven obstetric, and nine surgical journals represented five Latin American countries. Women held 17% (224/1,318) of board positions [p < 0.0001; 95% CI(0.14, 0.19)]. Women held fewer academic roles (14.3%, 155/1,084) compared to senior [28.9%, 64/221 (p < 0.001)] and non-academic roles [38.4%, 5/13 (p = 0.042)]. Surgical journals had fewer women (7.7%, 58/752) compared to anesthesia [25.5%, 52/204 (p = 0.006)] and obstetrics [31.5%, 114/362 (p < 0.001)]. Women's proportion on editorial boards increased according to the number of women SAO physicians per country (p < 0.001).
    CONCLUSIONS: Our study assessed the composition of editorial boards from Latin America SAO journals and demonstrated that women remain underrepresented. Our findings highlight the need for regional strategies to advance women's careers across SAO specialties.
    DOI:  https://doi.org/10.1007/s00268-022-06872-8
  38. Environ Sci Pollut Res Int. 2023 Jan 05.
      This study aims to assess the performance of thermophysical materials in the construction and building industry to establish the necessary academic basis for the interpretation of trends, developments, and status in this research field. The Scopus database contains 159 papers on this topic, which were published between 1968 and 2021 and originated in 60 countries. The International Organization for Standardization published significant information on thermal insulating materials, merchandize, elements, and applications. Several forms of insulation currently exist: (i) solid-state foam insulation composed of fibers, grains, and matrix; (ii) liquid-state insulation that encloses humidity within the filling; and (iii) gasifier form, which incorporates air, steam, or alternative gases. To reduce the amount of energy demanded, thermal insulation materials must be extended, current solutions must be modified, and new materials must be developed. Because high-temperature thermal insulation materials have more complex working conditions than alternative materials, their application requires further consideration.
    Keywords:  Bibliometric analysis; Energy and building; Thermal insulation materials; Thermal properties
    DOI:  https://doi.org/10.1007/s11356-022-25103-0
  39. Zhongguo Zhong Yao Za Zhi. 2022 Dec;47(23): 6505-6513
      This study aims to analyze the current status and development trend of the prevention and treatment of pulmonary nodules(PN) with traditional Chinese medicine(TCM) based on knowledge map and to provide both references and suggestions for future research directions. CNKI, Wanfang, VIP, and SinoMed were searched for relevant papers from the inception to December 31, 2021. Eligible articles were included according to the inclusion and exclusion criteria. The line chart was drawn based on the annual publication volume of articles, and the research interests of this field were learned. The knowledge maps of prevention and treatment of PN with TCM were drawn in CiteSpace 5.8.R1, and the authors, institutions, contents, and hotspots were analyzed. A total of 122 articles were included and the line chart demonstrated that the annual publication volume has been rising since 2018. According to the knowledge maps, the most prolific author was ZHANG Xiao-mei and there were four main research teams. Beijing University of Chinese Medicine and its affiliated hospitals were in a leading position in this field. The main research contents were disease, pathogenesis, and treatment, and the hotspots were data mining and TCM syndrome. The research on prevention and treatment of PN with TCM has become an increasing field of interest in recent years. In the future, the cross-regional cooperation and communication between research teams and institutions should be strengthened for more real-world studies and basic studies about the prevention and treatment of PN with TCM, so that the high-level evidence can be obtained and the underlying mechanisms of TCM formulae in the treatment of PN be clarified.
    Keywords:  CiteSpace; knowledge map; pulmonary nodules; traditional Chinese medicine; visualized analysis
    DOI:  https://doi.org/10.19540/j.cnki.cjcmm.20220829.501
  40. Health Serv Manage Res. 2023 Jan 04. 9514848221115089
      This study was conducted to determine the variables that play a role in the efficiency of Health Management departments in Turkey and the ranking of them in order of importance. These variables were determined by systematic analysis. The Prisma method was used in the systematic analysis approach. Input and output variables used in studies assessing the efficiency of higher education institutions in the literature were listed. The ranking of these variables was determined by Analytical Hierarchy Process (AHP) method. The questionnaire used for the AHP analysis and the judgments of 127 academicians working in Health Management Departments in universities in Turkey were assessed. The first three input variables found as a result of the AHP were "the number of registered undergraduate students per faculty member", "the number of faculty members", and "the number of other academic staff". The most important three output variables included "the number of articles searched on SCI, SSCI, SCI-E", "the number of papers presented in international congresses", and "the count of publications published in international peer-reviewed journals". To achieve positive developments in the efficiency of Health Management Departments, it is recommended to carry out studies to increase the number of qualified publications.
    Keywords:  analytical hierarchy process; efficiency; health management; systematic analysis
    DOI:  https://doi.org/10.1177/09514848221115089
  41. NPJ Digit Med. 2023 Jan 03. 6(1): 1
      When implemented in practice, digital technologies have shown improvements in morbidity and mortality outcomes in patients with cardiovascular disease (CVD). For scholars, research into digital technologies in cardiovascular care has been relatively recent, thus it is important to understand the history of digital health technology in cardiovascular research-its emergence, rate of growth, hot topics, and its temporal evolution. The aim of this study was to analyse more than 16,000 articles in this domain based on their scientometric indicators. Web of Science (WoS) Core Collection was accessed and searched at several levels, including titles, abstracts, keywords, authors, sources and individual articles. Analysis examined the temporal shifts in research and scholarly focus based on keywords, networks of collaboration, topical divisions in relation to digital technologies, and influential publications. Findings showed this research area is growing exponentially. Co-citation analysis revealed twenty prominent research streams and identified variation in the magnitude of activities in each stream. A recent emergence of research activities in digital technology in cardiovascular rehabilitation (CR), out-of-hospital cardiac arrest (OHCA), and arrythmia research was also demonstrated. Conversely, wearable technologies, activity tracking and electronic medical records research are now past their peak of reported research activity. With increasing amounts of novel technologies becoming available and more patients taking part in remote health care monitoring, further evaluation and research into digital technologies, including their long-term effectiveness, is needed. Furthermore, emerging technologies, which are evaluated and/or validated should be considered for implementation into clinical practice as treatment and prevention modalities for CVD.
    DOI:  https://doi.org/10.1038/s41746-022-00734-2
  42. Medicine (Baltimore). 2022 Dec 30. 101(52): e32369
      BACKGROUND: Spine trauma, vertebral metastases, and osteoporosis (SVO) can result in serious health problems. If the diagnosis of SVO is delayed, the prognosis may be deteriorated. The use of artificial intelligence (AI) is an essential method for minimizing the diagnostic errors associated with SVO. research achievements (RAs) of SVO on AI are required as a result of the greatest number of studies on AI solutions reported. The study aimed to: classify article themes using visualizations, illustrate the characteristics of SVO on AI recently, compare RAs of SVO on AI between entities (e.g., countries, institutes, departments, and authors), and determine whether the mean citations of keywords can be used to predict article citations.METHODS: A total of 31 articles from SVO on AI (denoted by T31SVOAI) have been found in Web of Science since 2018. The dominant entities were analyzed using the CJAL score and the Y-index. Five visualizations were applied to report: the themes of T31SVOAI and their RAs in comparison for article entities and verification of the hypothesis that the mean citations of keywords can predict article citations, including: network diagrams, chord diagrams, dot plots, a Kano diagram, and radar plots.
    RESULTS: There were five themes classified (osteoporosis, personalized medicine, fracture, deformity, and cervical spine) by a chord diagram. The dominant entities with the highest CJAL scores were the United States (22.05), the University of Pennsylvania (5.72), Radiology (6.12), and Nithin Kolanu (Australia) (9.88). The majority of articles were published in Bone, J. Bone Miner. Res., and Arch. Osteoporos., with an equal count (=3). There was a significant correlation between the number of article citations and the number of weighted keywords (F = 392.05; P < .0001).
    CONCLUSION: A breakthrough was achieved by displaying the characteristics of T31SVOAI using the CJAL score, the Y-index, and the chord diagram. Weighted keywords can be used to predict article citations. The five visualizations employed in this study may be used in future bibliographical studies.
    DOI:  https://doi.org/10.1097/MD.0000000000032369
  43. Nature. 2023 Jan;613(7942): 138-144
      Theories of scientific and technological change view discovery and invention as endogenous processes1,2, wherein previous accumulated knowledge enables future progress by allowing researchers to, in Newton's words, 'stand on the shoulders of giants'3-7. Recent decades have witnessed exponential growth in the volume of new scientific and technological knowledge, thereby creating conditions that should be ripe for major advances8,9. Yet contrary to this view, studies suggest that progress is slowing in several major fields10,11. Here, we analyse these claims at scale across six decades, using data on 45 million papers and 3.9 million patents from six large-scale datasets, together with a new quantitative metric-the CD index12-that characterizes how papers and patents change networks of citations in science and technology. We find that papers and patents are increasingly less likely to break with the past in ways that push science and technology in new directions. This pattern holds universally across fields and is robust across multiple different citation- and text-based metrics1,13-17. Subsequently, we link this decline in disruptiveness to a narrowing in the use of previous knowledge, allowing us to reconcile the patterns we observe with the 'shoulders of giants' view. We find that the observed declines are unlikely to be driven by changes in the quality of published science, citation practices or field-specific factors. Overall, our results suggest that slowing rates of disruption may reflect a fundamental shift in the nature of science and technology.
    DOI:  https://doi.org/10.1038/s41586-022-05543-x
  44. Res Policy. 2023 Jan;52(1): 104630
      Regional scientific integration is a critical pathway for the development of an integrated African research area and knowledge-based society. On the African continent, progress in scientific production and integration has remained limited, mostly led by a global or international agenda, and bound to a few top publishing nations. The high-level policy commitments and the accumulated policies and strategies developed and pursued under the various intertwined sub-regional economic groupings have, to date, only diversely contributed to policy alignment and coordination in the area of science, technology, and innovation (STI) across Africa. In this context, this paper provides a first and hence original assessment of the role of region-specific factors in shaping scientific collaboration on the continent. For this purpose, our study builds upon the proximity approach to analyse the determinants of scientific collaboration between African countries, using co-publications data from Thomson Reuters' Web of Science database as a proxy of such collaboration. Our results suggest that the majority of African regional economic communities (RECs) have not yet had a significant effect on scientific co-publication. Nevertheless, some important region-specific factors do seem to be at play, such as a shared ethnical language, membership in the African and Malagasy Council for Higher Education (CAMES), and the presence of a common European partner as a third partner in co-publication. Existing policies aimed at the development of an Africa-wide research area should aim to leverage existing and emerging regional excellence networks and novel coordination models to accelerate the process of scientific integration in Africa.
    Keywords:  African countries; Bibliometrics; Gravity model; Publications; Regional economic communities; Scientific collaborations
    DOI:  https://doi.org/10.1016/j.respol.2022.104630
  45. J Shanghai Jiaotong Univ Sci. 2022 Dec 26. 1-11
      Research in Information Science and interdisciplinary areas suggested the formation of a growing network of international research collaboration. The massive transmission of COVID-19 worldwide especially after the identification of the Omicron variant could fundamentally alter the factors shaping the network's development. This study employs network analysis methods to analyze the structure of the COVID-19 research collaboration from 2020 to 2022, using two major academic publication databases and the VOSviewer software. A novel temporal view is added by examining the dynamic changes of the network, and a fractional counting method is adopted as methodological improvements to previous research. Analysis reveals that the COVID-19 research network structure has undergone substantial changes over time, as collaborating countries and regions form and re-form new clusters. Transformations in the network can be partly explained by key developments in the pandemic and other social-political events. China as one of the largest pivots in the network formed a relatively distinct cluster, with potential to develop a larger Asia-Pacific collaboration cluster based on its research impact.
    Keywords:  COVID-19; high interdisciplinary research; international research collaboration; network analysis
    DOI:  https://doi.org/10.1007/s12204-022-2558-7
  46. Sci Total Environ. 2023 Jan 02. pii: S0048-9697(22)08418-2. [Epub ahead of print] 161314
      Greenhouse gas (GHG) concentrations have continued to increase in the atmosphere and unequivocally warmed the climate system, and human activities contribute significantly to the growth impact. Various research puzzles and potential mitigation evidence involving GHG related research (GRR) need to be explored and deciphered from large-scale literature records to provide a whole picture and clear scientific view on the current state of GRR to promoting action on climate change. By combining Bibexcel-based bibliometrics with Pajek's social network analysis, we explore the literature statistics and interdisciplinary characteristics of GRR, and identify frequently debated topics in interdisciplinary by going deep into the texts of those classical literature. We found the trend of GRR's publications in the Environmental/Ecology group increased exponentially with an annual growth rate of 47.3 % and continue to expand in 13 subject categories. There are four types of relationships in the author cooperation, which gradually promote the cross-study of GHG in different subject categories, and the regional cooperation relations are relatively stable involving North America, Asia, Europe, Oceania, and South America. Those classical literature are widely distributed in six interdisciplinary categories, specifically 'Agronomy, Forestry and Zoology', 'Biodiversity Conservation and Ecology', 'Engineering, Environmental and Green & Sustainable Science & Technology', 'Geography and Remote Sensing', 'Limnology, Marine & Freshwater Biology and Water Resources', and 'Public, Environmental & Occupational Health'.
    Keywords:  Bibliometrics; GHG-related research; Interdisciplinary; Social network analysis; Subject categories
    DOI:  https://doi.org/10.1016/j.scitotenv.2022.161314
  47. J Palliat Med. 2023 Jan;26(1): 13-16
      The Journal of Palliative Medicine (JPM) is globally recognized as a leading interdisciplinary peer-reviewed palliative care journal providing balanced information that informs and improves the practice of palliative care. JPM shapes the values, integrity, and standards of the subspecialty of palliative medicine by what it chooses to publish. The global JPM readership chooses to download the articles that are of most relevance and utility to them. Utilizing machine learning methods, the top 100 most downloaded articles in JPM were analyzed to gain a better understanding of any latent trends and patterns in the topics between 1999 and 2018. The top five topic themes identified in the first decade were different from the ones identified in the second decade of publication. There is evidence of differentiation and maturation of the field in the context of comprehensive health care. Although noncancer serious illnesses have still not risen to the same prominence as cancer palliation, there is a directional quality to the emerging evidence as it pertains to cardiac, respiratory, neurological, renal, and other etiologies. Across both decades under study, there was persistent evidence of the importance of understanding and managing the mental health care needs of seriously ill patients and their families. A cause for concern is that the word "spirituality" was prominent in the first decade and was lacking in the second. Future palliative care clinical and research initiatives should focus on its development as an essential interprofessional and medical subspecialty germane to all types of serious illnesses and across all venues.
    Keywords:  artificial intelligence; latent Dirichlet allocation; machine learning methods; palliative care; topic modeling
    DOI:  https://doi.org/10.1089/jpm.2022.0574
  48. Nature. 2023 Jan 04.
      
    Keywords:  Authorship; Publishing; Research data; Scientific community
    DOI:  https://doi.org/10.1038/d41586-022-04577-5
  49. Front Public Health. 2022 ;10 1050035
      This study quantitatively analyzed healthcare administration studies in Japan using text mining, focusing on articles published during 1994-2021 in the Journal of the Japan Society for Healthcare Administration (prior to 2008, the journal was called Hospital Administration). Both the co-occurrence network and the correspondence analysis (these are extracted words that refer to the two systems) demonstrate two major changes: (1) the introduction of the long-term care insurance system, which was enacted in 1997 and came into effect in 2000, and (2) the introduction of the late-stage medical care system for the elderly in 2008, both of which had a significant impact on the Japanese public health and welfare system. Co-occurrence network and correspondence analysis were conducted to understand changes in research interests. The analysis used two time periods following a change in the journal's name in 2008. To readily comprehend changing research trends, 10-year segments were considered, resulting in three time periods. The research features and trends during the aforementioned periods were examined using correspondence analysis. Configuration figures derived from this analysis plotted time transition (first dimension) against certain abstract/concrete situations (second dimension). The extracted words displayed in the configuration maps at the axes' intersection were patient, survey, and evaluation. They revealed no distinctive features compared with other words and were commonly used in article titles within this journal during each period. The following results were obtained from the correspondence analysis: first, changes in the geriatric care system of public medical insurance and the introduction of the long-term care insurance system in 2000 were expressed in the characteristics of the extracted words; second, in the 14 years after the journal's name changed, published studies frequently referred to the roles of doctors, nurses, and other healthcare professionals. A chi-squared test on these extracted words and the period classification confirmed a statistically significant relationship between them.
    Keywords:  Japan; content analysis; correspondence analysis; healthcare administration; hospitals; public medical insurance; research trends
    DOI:  https://doi.org/10.3389/fpubh.2022.1050035
  50. Environ Geochem Health. 2023 Jan 04.
      Microplastics (MPs) have become increasingly serious global problems due to their wide distribution and complicated impacts on living organisms. To obtain a comprehensive overview of the latest research progress on MPs, we conducted a bibliometric analysis combined with a literature review. The results showed that the number of studies on MPs has grown exponentially since 2010. Recently, the hotspot on MPs has shifted to terrestrial ecosystems and biological health risks, including human health risks. In addition, the toxic effects, identification and quantification of MPs are relatively new research hotspots. We subsequently provide a review of MPs studies related to health risks to terrestrial higher mammals and, in particular, to humans, including detection methods and potential toxicities based on current studies. Currently, MPs have been found existing in human feces, blood, colon, placenta and lung, but it is still unclear whether this is associated with related systemic diseases. In vivo and in vitro studies have demonstrated that MPs cause intestinal toxicity, metabolic disruption, reproductive toxicity, neurotoxicity, immunotoxicity through oxidative stress, apoptosis and specific pathways, etc. Notably, in terms of combined effects with pollutants and neurotoxicity, the effects of MPs are still controversial. Future attention should be paid to the detection and quantification of MPs in human tissues, exploring the combined effects and related mechanisms of MPs with other pollutants and clarifying the association between MPs and the development of pre-existing diseases. Our work enhances further understanding of the potential health risks of MPs to terrestrial higher mammals.
    Keywords:  Bibliometrics; Detection methods; Microplastics; Research trend; Terrestrial higher mammals; Toxicity
    DOI:  https://doi.org/10.1007/s10653-022-01458-8
  51. Front Med (Lausanne). 2022 ;9 1071254
      Thoracic surgery has increased drastically in recent years, especially in light of the severe outbreak of the 2019 novel coronavirus disease (COVID-19). Routine "passive" chest computed tomography (CT) screening of inpatients detects some pulmonary diseases requiring thoracic surgeries timely. As an essential device for thoracic anesthesia, the double-lumen tube (DLT) is particularly important for anesthesia and surgery. With the continuous upgrading of the DLTs and the widespread use of fiberoptic bronchoscopy (FOB), the position of DLT in thoracic surgery is gradually becoming more stable and easier to observe or adjust. However, DLT malposition still occurs during transferring patients from a supine to the lateral position in thoracic surgery, which leads to lung isolation failure and hypoxemia during one-lung ventilation (OLV). Recently, some innovative DLTs or improved intervention methods have shown good results in reducing the incidence of DLT malposition. This review aims to summarize the recent studies of the incidence of left-sided DLT malposition, the reasons and effects of malposition, and summarize current methods for reducing DLT malposition and prospects for possible approaches. Meanwhile, we use bibliometric analysis to summarize the research trends and hot spots of the DLT research.
    Keywords:  airway management; bibliometric analysis; double lumen tube; fiberoptic bronchoscopy; malposition; one-lung ventilation; thoracic surgery
    DOI:  https://doi.org/10.3389/fmed.2022.1071254