bims-evares Biomed News
on Evaluation of research
Issue of 2023‒10‒29
seventy papers selected by
Thomas Krichel, Open Library Society



  1. Arch Bone Jt Surg. 2023 ;11(9): 545-555
      Objectives: Bibliometric analysis is one of the most prevalent methods for analyzing and predicting the research trends of particular subjects. Through a bibliometric analysis, this study sought to look into and depict the hotspots and research trends in knee arthroplasty research over the previous five years.Methods: The Web of Science Core Collection database was used to find research articles on knee arthroplasty published between 2018 and 2022. The VOS viewer, Cite Space, and Bibliometrix were used to carry out the bibliometric study and network visualization.
    Results: During the previous five years, 7,422 included knee arthroplasty publications were cited 57,087 times. The United States and the Journal of Arthroplasty were the top countries and journals regarding the number of articles. The top 10 global high-impact documents were determined using the citation ranking and citation burst. The most frequently referenced article revealed that the epidemiological characteristics of knee arthroplasty, perioperative care in knee arthroplasty, prosthetic joint infections, and opioid medications were the hot topics in knee arthroplasty research. Keyword burst analysis showed that the research trends in knee arthroplasty through 2022 were racial disparity, limb alignment, tibial slope, and meniscectomy. The analysis of the subject areas revealed the close connections and relationships between different subject areas, as demonstrated by the figures.
    Conclusion: The knee arthroplasty research community is highly productive and centralized. Recent hotspots in knee arthroplasty research were unicompartmental knee arthroplasty, periprosthetic joint infection, kinematic alignment, outpatient total knee arthroplasty (TKA), bariatric surgery, payment model, tranexamic acid, Robotic-Assisted TKA, patient-reported outcome measures, metaphyseal cone, opioid use, and patient-specific instrumentation. Research trends in knee arthroplasty research were racial disparity, limb alignment, tibial slope, and meniscectomy.
    Keywords:  Bibliometric analysis; Knee arthroplasty; Knee replacement; Trends; Visualization
    DOI:  https://doi.org/10.22038/ABJS.2023.70791.331
  2. Quant Imaging Med Surg. 2023 Oct 01. 13(10): 6801-6813
      Background: Dual-energy computed tomography (DECT) has received extensive attention in clinical practice; however, a quantitative assessment of published literature in this domain is presently lacking. This study thus aimed to characterize the application conditions, developmental trends, and research hot spots of DECT using bibliometric analysis.Methods: All literature on DECT was retrieved from the Web of Science Core Collection (WoSCC) on January 22, 2023. The co-occurrence, cooperation network, and co-citation of countries, institutions, references, authors, journals, and keywords were analyzed using CiteSpace, VOSviewer, and R-bibliometrix software.
    Results: In total, 4,720 original articles and reviews were included. The number of publications related to DECT has rapidly increased since 2006. The USA (n=1,662) and Mayo Clinic (n=178) were found to be the most productive country and institution, respectively. The most cited article was published by Johnson TRC et al., while the article published by McCollough CH et al. in 2015 had the most co-citations. Schoepf UJ ranked first with most articles among 16,838 authors. The journal with the most published articles was European Radiology, with 411 publications. The timeline analysis indicated that material decomposition was the most recent topic, followed by gout, radiomics, proton therapy, and bone marrow edema.
    Conclusions: An increasing number of researchers are committed to researching DECT, with the USA making the most significant contributions in this area. Prior studies have primarily concentrated on cardiovascular diseases, and contemporary hot spots include expansion into to other fields, such as iodine quantification, deep learning, and bone marrow edema.
    Keywords:  Dual-energy computed tomography (DECT); bibliometrics; cocitation
    DOI:  https://doi.org/10.21037/qims-23-467
  3. Quant Imaging Med Surg. 2023 Oct 01. 13(10): 6911-6928
      Background: As a noninvasive diagnostic tool, fluorine-18-labelled sodium fluoride positron emission tomography ([18F]NaF PET) has been increasingly applied in clinical practice due to its excellent imaging performance, attracting more attention from clinical practitioners. However, with the continuous development of technology and growth of knowledge, the field of [18F]NaF PET is changing. Nevertheless, few studies have conducted quantitative analyses of the literature in this field. Therefore, in this study, we used bibliometric methods to analyze the trends, content distribution, and frontiers of this field from multiple perspectives, including social and international structure, conceptual structure, and intellectual structure.Methods: This study used the Web of Science (WOS) core database as the data source and retrieved literature related to [18F]NaF PET between 2008 and 2022. CiteSpace and VOSviewer software were then employed for bibliometric analysis. This study performed co-occurrence analysis and citation analysis to investigate the characteristics of [18F]NaF PET in 3 aspects.
    Results: A total of 682 articles related to [18F]NaF PET were collected during the period from 2008 to 2022. The author, Alavi, had the highest number of publications (67 articles). In terms of institutions, the University of Edinburgh had the highest number of publications (64 articles). The United States (300 articles) was the country with the highest number of published articles. Keyword co-occurrence analysis revealed that [18F]NaF PET-related technologies, bone metastasis (prostate cancer and breast cancer), and atherosclerosis were prominent research directions in this field. In terms of highly cited authors, Even-Sapir had the highest citation count (188 citations). Regarding highly cited journals, the Journal of Nuclear Medicine ranked as the most highly cited journal. The literature co-citation clustering and timeline graph showed that atherosclerotic plaques, bone metastasis, and the clinical applications of [18F]NaF PET were topics of active research in this field.
    Conclusions: There has been an increase in the literature published in the field of [18F]NaF PET from 2008 to 2022. The United States holds a prominent position in the field of [18F]NaF PET. Arteriosclerosis and bone metastasis are the main topics in this field and at the forefront of research.
    Keywords:  CiteSpace; Fluorine-18-labelled sodium fluoride positron emission tomography ([18F]NaF PET); VOSviewer; bibliometrics
    DOI:  https://doi.org/10.21037/qims-23-703
  4. Clin Exp Optom. 2023 Oct 24. 1-8
      CLINICAL RELEVANCE: A bibliometric analysis is a quantitative study that utilises methods such as citation analysis to evaluate research performance. A bibliometric analysis could provide a valuable reference for ophthalmic researchers to understand the trends in epigenetics research.BACKGROUND: The number of studies on epigenetics in eye diseases has exceeded 5,000, but the progress and scope of epigenetic research on eye diseases remain unclear. The study aimed to bibliometrically analyse epigenetic research conducted in eye diseases.
    METHODS: Studies concerning epigenetic research on eye diseases from 2000-2023 were searched using the Web of Science Core Collection. Following this, the included studies were analysed for citations, journals, keywords, authors, and countries, using the Bibliometrix package in R Studio.
    RESULTS: In total, 3758 studies were included in the analysis, including 3099 original articles, 599 reviews, 11 editorials, and 49 early access articles. Investigative Ophthalmology & Visual Science was the most published journal with 185 articles, and Proceedings of the National Academy of Sciences of the United States of America was the most cited journal, with 8727 citations. The journal with the highest h-index was Oncogene (h-index = 38).Renu A Kowluru from the Kresge Eye Institute, Wayne State University, Detroit, USA, had the most citations with 1,690 and the highest h-index (h-index = 23). China and the USA were the countries with the highest number of publications (1739) and total citations (40533), respectively. Furthermore, from 2000-2023, the top five frequent research topics were diabetic retinopathy, 522; microribonucleic acid, 469; retinoblastoma, 370; apoptosis, 268; and epigenetics, 206.
    CONCLUSIONS: The results of this bibliometric study provide the current status and trends of epigenetic research in eye diseases and will help researchers identify areas of current interest in the field, which should help highlight new research directions.
    Keywords:  Bibliometrics; diabetic retinopathy; epigenetics; eye diseases; ocular surface; ophthalmic research
    DOI:  https://doi.org/10.1080/08164622.2023.2261929
  5. Nanotechnology. 2023 Oct 25.
      OBJECTIVE: 
Aptamer-conjugated nanoparticles for diagnosis have recently gained increasing attention. Here, we performed a bibliometric analysis to provide an overview of this field over the past two decades.
Methods:
The terms "aptamer, nanoparticles, and diagnosis" were used to search for relevant original articles published in English from 2003 to 2022 in the Web of Science database. VOSviewer and CiteSpace software were employed to analyze the development process, knowledge structure, research hotspots, and potential trends in the field of aptamer-conjugated nanoparticles for diagnosis.
Results:
A total of 1,076 original articles were retrieved, with a rapid increase in the annual output and citation. The journal "Biosensors & Bioelectronics" has contributed the most in this field, and the most influential researcher, institution and country were Weihong Tan, the Chinese Academy of Sciences, China, respectively. Gold nanoparticles and quantum dots were the most used, but in the past three years, research hotspots focused on carbon dots and graphene quantum dots. Diagnostic directions primarily focused on cancer. The most used strategy was label-free electrochemical detection, but in the past two years, colorimetric analysis and fluorescence imaging emerged as hot topics.
Conclusion:
The bibliometric analysis reveals a rapid increase in the research on aptamer-conjugated nanoparticles for diagnosis, major contributors at the levels of journals, authors, institutions, and countries, and research preferences in diagnostic objects, nanoparticle types, and detection methods, as well as the evolution of research hotspots and future trends.&#xD.
    Keywords:  aptamer; bibliometric analysis; diagnosis; nanoparticles; publication
    DOI:  https://doi.org/10.1088/1361-6528/ad06d5
  6. J Clin Nurs. 2023 Oct 25.
      No Patient or Public Contribution, because the relevant data of this article comes from the literature database.PURPOSE: The present study aimed to investigate the trends and research status of sexual healthcare.
    METHODS: We searched the Web of Science database for relevant articles concerning sexual healthcare, published between 2009 and 31 December 2022. Data collected include: the number of publications, authors, journals, countries, institutions, keywords. VOSviewer and CiteSpace were used to conduct the bibliometric study and visualise the analysis.
    RESULTS: A total of 1450 publications were included. The number of publications on sexual healthcare shows a fluctuating upward trend, and a stable core group of authors has been formed. The Journal of Clinical Nursing published the most articles on sexual healthcare (140 publications). The United States of America published the most articles (723, 49.86%). The research institution with the highest number of publications is the University of São Paulo. According to the keyword, timeline view and prominence mapping analysis, we believe that 'Female sexual health', 'HIV', 'LGBT' and 'Sexual Healthcare Services' may be new research hotspots in the field of sexual healthcare.
    CONCLUSION: This study describes the research status of sexual healthcare research over the past 14 years. The findings of this study can provide helpful reference and guidance for the development trend and research direction of sexual healthcare.
    Keywords:  bibliometric analysis; global trends; sexual healthcare; visualized analysis
    DOI:  https://doi.org/10.1111/jocn.16915
  7. Iran J Parasitol. 2023 Jul-Sep;18(3):18(3): 369-381
      Background: Paragonimus is a genus of parasitic flatworms known as lung flukes that cause the parasitic disease paragonimiasis in humans and other mammals. We aimed to use bibliometric analysis to identify the global characteristics and temporal trends of published literature about paragonimiasis.Methods: Using the Web of Science database, we identified all original articles on paragonimiasis 1997 to 2022. After collecting the bibliographic and citation data, keywords, citation networks, and co-citations pertaining to paragonimiasis was carried out using the VOSviewer program.
    Results: The study identified 563 paragonimiasis articles published in 250 journals. Publications in paragonimiasis research have been cited 6190 times and 2803 times without self-citations. The years with the most publications were 2013, 2016, and 2021. The minimal threshold for analysis was met by 19 of the 52 countries investigated. The study included 19 items, yielding 170 links between countries. The total strength of these links was discovered to be 104772. The journal with the most publications in this category was Parasitology Research (n=31). The most frequently used terms in paragonimiasis study were "paragonimiasis", "Paragonimus westermanii", and "lung-fluke."
    Conclusion: The study concluded by providing an overview of the paragonimiasis research field, including current trends, development, and researcher collaboration. By addressing gaps in this bibliometric analysis and increasing collaboration, stake-holders could strengthen their strategies to effectively combat paragonimiasis and improve public health outcomes.
    Keywords:  Bibliometric; Paragonimiasis; Paragonimus westermanii
    DOI:  https://doi.org/10.18502/ijpa.v18i3.13760
  8. Curr Oncol. 2023 Oct 05. 30(10): 9004-9018
      The research domain investigating bacterial factors in the development of oral cancer from January 2013 to December 2022 was examined with a bibliometric analysis. A bibliometric analysis is a mathematical and statistical method used to examine extensive datasets. It assesses the connections between prolific authors, journals, institutions, and countries while also identifying commonly used keywords. A comprehensive search strategy identified 167 relevant articles, revealing a progressive increase in publications and citations over time. China and the United States were the leading countries in research productivity, while Harvard University and the University of Helsinki were prominent affiliations. Prolific authors such as Nezar Al-Hebshi, Tsute Chen, and Yaping Pan were identified. The analysis also highlights the contributions of different journals and identifies the top 10 most cited articles in the field, all of which focus primarily on molecular research. The article of the highest citation explored the role of a Fusobacterium nucleatum surface protein in tumor immune evasion. Other top-cited articles investigated the correlation between the oral bacteriome and cancer using 16S rRNA amplicon sequencing, showing microbial shifts associated with oral cancer development. The functional prediction analysis used by recent studies has further revealed an inflammatory bacteriome associated with carcinogenesis. Furthermore, a keyword analysis reveals four distinct research themes: cancer mechanisms, periodontitis and microbiome, inflammation and Fusobacterium, and risk factors. This analysis provides an objective assessment of the research landscape, offers valuable information, and serves as a resource for researchers to advance knowledge and collaboration in the search for the influence of bacteria on the prevention, diagnosis, and treatment of oral cancer.
    Keywords:  bacteria; bibliographic; bibliometrics; databases; mouth neoplasms
    DOI:  https://doi.org/10.3390/curroncol30100650
  9. J Anal Toxicol. 2023 Oct 27. pii: bkad080. [Epub ahead of print]
      Soon approaching its 50th anniversary, Journal of Analytical Toxicology (JAT) is an international scholarly publication specializing in analytical and forensic aspects of toxicology. Science Citation Index (SCI) and Journal Citation Reports (JCR), both of which are part of the Web-of-Science (WOS) database, were used to make a bibliometric evaluation of JAT articles. Between 1977 (volume 1) and 2023 (volume 47), a total of = n = 4,785 items were published in JAT; the top-ten most highly cited articles and the most prolific authors were identified. Changes in the journal impact factor (JIF) were studied between 1997 and 2022 and this metric varied from a low of 1.24 (2006) to a high of 3.36 (2020).The most recent JIF (2022) dropped to 2.5 and the corresponding 5-year JIF was 2.6. JAT's most highly article (590 cites) was a working group (SWTOX) report dealing with methods recommended for the validation analytical methods used in forensic toxicology laboratories. JAT published 62 articles each of which were cited over 100 times and the H-index for JAT was 89. The most prolific author of JAT articles was credited with 119 items, the first in 1980 (volume 4) and the latest in 2023 (volume 47). JAT articles were cited 4,537 times in 2022 by all journals in the JCR database, although 520 of these were self-citations (11.5%). Bibliometric methods are increasingly used to evaluate the published work of individual scientists, university departments, entire universities, and whole countries. Highly cited articles are considered more influential and authoritative compared with papers that are seldom or never cited.
    Keywords:  Analytical toxicology; Authorship; Bibliometrics; Citation analysis; Forensic Toxicology; Journal impact factor; Science citation index
    DOI:  https://doi.org/10.1093/jat/bkad080
  10. Nutrients. 2023 Oct 10. pii: 4320. [Epub ahead of print]15(20):
      In the last few decades, numerous studies pertaining to research groups worldwide have investigated the effects of oral caffeine intake on fat oxidation at rest, during exercise, and after exercise. However, there is no bibliometric analysis to assess the large volume of scientific output associated with this topic. A bibliometric analysis of this topic may be used by researchers to assess the current scientific interest in the application of caffeine as a nutritional strategy to augment fat oxidation, the journals with more interest in this type of publication, and to draw international collaborations between groups working in the same area. For these reasons, the purpose of this study was to assess the research activity regarding oral caffeine intake and fat oxidation rate in the last few decades by conducting a bibliometric and visual analysis. Relevant publications from 1992 to 2022 were retrieved from the Web of Science (WoS) Core Collection database. Quantitative and qualitative variables were collected, including the number of publications and citations, H-indexes, journals of citation reports, co-authorship, co-citation, and the co-occurrence of keywords. There were 182 total publications, while the number of annual publications is saw-shaped with a modest increase of 11.3% from 2000 to 2009 to 2010 to 2019. The United States was the country with the highest number of publications (24.17% of the total number of articles), followed by the Netherlands (17.03%). According to citation analyses, the average number of citations per document is 130, although there are 21 documents that have received more than 100 citations; the most cited document reached 644 citations. These citation data support the overall relevance of this topic in the fields of nutrition and dietetics and sport sciences that when combined harbored 85.71% of all articles published in the WoS. The most productive author was Westerterp-Plantenga with 16 articles (8.79% of the total number of articles). Nutrients was the journal that published the largest number of articles on this topic (6.59% of the total number of articles). Last, there is a tendency to include keywords such as "performance", "carbohydrate", and "ergogenic aid" in the newer articles, while "obesity", "thermogenic", and "tea" are the keywords more commonly included in older documents. Although research into the role of caffeine on fat oxidation has existed since the 1970s, our analysis suggests that the scientific output associated with this topic has progressively increased since 1992, demonstrating that this is a nutritional research area with a strong foundational base of scientific evidence. Based on the findings of this bibliometric analysis, future investigation may consider focusing on the effects of sex and tolerance to caffeine to widen the assessment of the effectiveness of oral caffeine intake as a nutritional strategy to augment the use of fat as a fuel, as these terms rarely appear in the studies included in this analysis. Additionally, more translational research is necessary as the studies that investigate the effect of oral caffeine intake in ecologically valid contexts (i.e., exercise training programs for individuals with excessive adiposity) are only a minor part of the studies on this topic.
    Keywords:  bibliometric analysis; caffeine effects; coffee; dietary supplement; fat loss; weight loss
    DOI:  https://doi.org/10.3390/nu15204320
  11. Bioengineering (Basel). 2023 Sep 28. pii: 1138. [Epub ahead of print]10(10):
      This study aims to highlight recent research work on topics around prosthetic feet through a scientometric analysis and historical review. The most cited publications from the Clarivate Analytics Web of Science Core Collection database were identified and analyzed from 1 January 2000 to 31 October 2022. Original articles, reviews with full manuscripts, conference proceedings, early access documents, and meeting abstracts were included. A scientometric visualization analysis of the bibliometric information related to the publications, including the countries, institutions, journals, references, and keywords, was conducted. A total of 1827 publications met the search criteria in this study. The related publications grouped by year show an overall trend of increase during the two decades from 2000 to 2022. The United States is ranked first in terms of overall influence in this field (n = 774). The Northwestern University has published the most papers on prosthetic feet (n = 84). Prosthetics and Orthotics International has published the largest number of studies on prosthetic feet (n = 151). During recent years, a number of studies with citation bursts and burst keywords (e.g., diabetes, gait, pain, and sensor) have provided clues on the hotspots of prosthetic feet and prosthetic foot trends. The findings of this study are based on a comprehensive analysis of the literature and highlight the research topics on prosthetic feet that have been primarily explored. The data provide guidance to clinicians and researchers to further studies in this field.
    Keywords:  bibliometric analysis; lower-extremity amputation; prosthetic foot; scientometric analysis; visualization
    DOI:  https://doi.org/10.3390/bioengineering10101138
  12. Int J Mol Sci. 2023 Oct 19. pii: 15377. [Epub ahead of print]24(20):
      Glaucoma is similar to a neurodegenerative disorder and leads to global irreversible loss of vision. Despite extensive research, the pathophysiological mechanisms of glaucoma remain unclear, and no complete cure has yet been identified for glaucoma. Recent studies have shown that microRNAs can serve as diagnostic biomarkers or therapeutic targets for glaucoma; however, there are few bibliometric studies that focus on using microRNAs in glaucoma research. Here, we have adopted a bibliometric analysis in the field of microRNAs in glaucoma research to manifest the current tendencies and research hotspots and to present a visual map of the past and emerging tendencies in this field. In this study, we retrieved publications in the Web of Science database that centered on this field between 2007 and 2022. Next, we used VOSviewer, CiteSpace, Scimago Graphica, and Microsoft Excel to present visual representations of a co-occurrence analysis, co-citation analysis, tendencies, hotspots, and the contributions of authors, institutions, journals, and countries/regions. The United States was the main contributor. Investigative Ophthalmology and Visual Science has published the most articles in this field. Over the past 15 years, there has been exponential growth in the number of publications and citations in this field across various countries, organizations, and authors. Thus, this study illustrates the current trends, hotspots, and emerging frontiers and provides new insight and guidance for searching for new diagnostic biomarkers and clinical trials for glaucoma in the future. Furthermore, international collaborations can also be used to broaden and deepen the field of microRNAs in glaucoma research.
    Keywords:  CiteSpace; VOSviewer; bibliometric analysis; collaboration network; glaucoma; microRNAs
    DOI:  https://doi.org/10.3390/ijms242015377
  13. Front Endocrinol (Lausanne). 2023 ;14 1273634
      Background: Glioma is a prevalent and lethal brain malignancy; despite current treatment options, the prognosis remains poor. Therefore, immunotherapy has emerged as a promising therapeutic strategy. However, research trends and hotspots in glioma immunotherapy have not been systematically analyzed. This study aimed to elucidate global research trends and knowledge structures regarding immunotherapy for glioma using bibliometric analysis.Methods: Publications related to immunotherapy for glioma from 2000-2023 were retrieved from Web of Science Core Collection database (WoSCC). We conducted quantitative analysis and visualization of research trends using various tools, including VOSviewer (1.6.18), CiteSpace (5.7 R3), Microsoft Charticulator, and the Bibliometrix package in R.
    Results: A total of 4910 publications were included. The number of annual publications exhibited an obvious upward trend since 2019. The USA was the dominant country in terms of publication output and centrality. Frontiers in Immunology published the most articles. Harvard Medical School ranked first in productivity among institutions. Sampson, John H. Ph.D. is the most prolific author in the field with 88 articles and a total of 7055 citations. Clinical Cancer Research has the largest total number and impact factor. Analysis of keywords showed immunotherapy, glioblastoma, immunotherapy, and clinical trials as hot topics. The tumor microenvironment, cell death pathways, chimeric antigen receptor engineering, tumor-associated macrophages, and nivolumab treatment represent indicating shifts in the direction of future glioma immunotherapy development.
    Conclusion: This bibliometric analysis systematically delineated global landscapes and emerging trends in glioma immunotherapy research. This study highlighted the prominence of Chimeric Antigen Receptor T-cell (CAR-T), Programmed Death-1 (PD-1), and nivolumab in current glioma immunotherapy research. The growing emphasis on specific neoantigens and prognostic tumor markers suggests potential avenues for future exploration. Furthermore, the data underscores the importance of strengthened international collaboration in advancing the field.
    Keywords:  CAR-T; Citespace; VOSviewer; bibliometric; glioma; immunotherapy
    DOI:  https://doi.org/10.3389/fendo.2023.1273634
  14. J Int Soc Prev Community Dent. 2023 Jul-Aug;13(4):13(4): 265-272
      Aims and Objectives: To perform a bibliometric study to identify and evaluate articles associated with "orthodontic wires" indexed in six databases (PubMed, Embase, Cochrane, Scopus, Lilacs, and Google Scholar) from 2010 to 2022.Materials and Methods: The search strategy in PubMed combined different medical subject heading terms with free-text words and was adjusted for each selected database. The retrieved documents were original English articles containing the keywords used in the search strategies related to orthodontic wires. Collected data consisted of journal name, nationality, field, JIF-2 and JIF-5, SJR, CiteScore, Q and H-index, and categorization of the study.
    Results: In total, 417 articles were retrieved from the initial search. After the exclusion criteria, 257 articles remained. The most common theme was mechanical properties, with basic studies as the main categorization.
    Conclusions: This bibliometric survey provides an overview of orthodontic wires publications that might help orthodontists to understand the tendency of the studies on this subject. The retrieved papers were published in 100 journals, including 15 orthodontic journals, mainly in the first and second quartiles. Europe and America were the continents with the highest number of papers. The United States was the country with the highest number of journals on the topic. AJODO presented the highest h-index among the retrieved orthodontic journals. Brazil represented the principal institutions of origin of the listed articles. There was a tendency to increase the number of publications on orthodontic wires over the years. These findings indicate that research on orthodontic wires is still contemporary and relevant.
    Keywords:  Bibliometrics; citation databases; orthodontic wires; orthodontics
    DOI:  https://doi.org/10.4103/jispcd.JISPCD_47_23
  15. Quant Imaging Med Surg. 2023 Oct 01. 13(10): 7012-7028
      Background: Radiology plays a highly crucial role in the diagnosis, treatment, and prognosis prediction of dilated cardiomyopathy (DCM). Related research has increased rapidly over the past few years, but systematic analyses are lacking. This study thus aimed to provide a reference for further research by analyzing the knowledge field, development trends, and research hotspots of radiology in DCM using bibliometric methods.Methods: Articles on the radiology of DCM published between 2002 and 2021 in the Web of Science Core Collection database (WoSCCd) were searched and analyzed. Data were retrieved and analyzed using CiteSpace V, VOSviewer, and Scimago Graphic software, and included the name, research institution, and nationality of authors; journals of publication; and the number of citations.
    Results: A total of 4,257 articles were identified on radiology of DCM from WoSCCd. The number of articles published in this field has grown steadily from 2002 to 2021 and is expected to reach 392 annually by 2024. According to subfields, the number of papers published in cardiac magnetic resonance field increased steadily. The authors from the United States published the most (1,364 articles, 32.04%) articles. The author with the most articles published was Bax JJ (54 articles, 1.27%) from Leiden University Medical Center. The most cited article was titled "2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure", with 138 citations. Citation-based clustering showed that arrhythmogenic cardiomyopathy, T1 mapping, and endomyocardial biopsy are the current hots pots for research in DCM radiology. The most frequently occurring keyword was "dilated cardiomyopathy". The keyword-based clusters mainly included "late gadolinium enhancement", "congestive heart failure", "cardiovascular magnetic resonance", "sudden cardiac death", "ventricular arrhythmia", and "cardiac resynchronization therapy".
    Conclusions: The United States and Northern Europe are the most influential countries in research on DCM radiology, with many leading distinguished research institutions. The current research hots pots are myocardial fibrosis, risk stratification of ventricular arrhythmia, the prognosis of cardiac resynchronization therapy (CRT) treatment, and subtype classification of DCM.
    Keywords:  Dilated cardiomyopathy (DCM); bibliometric analysis; cardiac imaging; cardiovascular medicine; radiology
    DOI:  https://doi.org/10.21037/qims-23-34
  16. J Pain Res. 2023 ;16 3491-3502
      Background: The postoperative acute pain caused by surgery has been a major problem plaguing anesthesiologists, and even some acute pain progresses to chronic pain syndrome, terribly reducing the quality of life of patients. To this end, increasing attention has been paid to the management of perioperative analgesia. At present, with the increase of research on perioperative analgesia, the understanding and solution of this clinical problem have been further developed. Bibliometrics can estimate research hot-spots and trends of related fields in a certain period of time. However, a systematic bibliometric analysis has not been conducted to explore current research hotspots and future development trends, which is thus the purpose of this study.Methods: Articles and reviews published from 2012 to 2021 were retrieved from the Web of Science Core Collection (WoSCC) database, and the bibliometric analysis of the keywords and references of articles was performed using VOSviewer1.6.18. Besides, the number of articles related to perioperative analgesia in term of countries, affiliations, authors, and journals were analyzed.
    Results: Finally, 3157 articles meeting the screening requirements were retrieved, and it was hereby found that the research on perioperative analgesia had received more attention and interest in the past 10 years, with the United States making more contributions, where there were eight of the top ten affiliations by the number of publications. Kaye AD was the most active researcher in this field. Most related articles were published in Anesthesia and Analgesia, accounting for 2.76% of all literature. Enhanced recovery after surgery, different types of anesthesia and multi-mode analgesic drug intervention were the main trends and hotspots.
    Conclusion: Perioperative analgesia has attracted considerable academic interest. In the past decade, the effects of enhanced recovery after surgery, different types of anesthesia and multi-mode analgesic drug intervention on perioperative analgesia have become the research hotspots, which are also likely to be the focus of future study.
    Keywords:  VOSviewer; bibliometrics; enhanced recovery after surgery; pain; perioperative analgesia
    DOI:  https://doi.org/10.2147/JPR.S429719
  17. Clin Exp Dent Res. 2023 Oct 25.
      OBJECTIVES: This bibliometric analysis aimed to evaluate the leading nations, authors, journals, institutes, highly cited publications, and most commonly used keywords concerning scientific publications based on root and root canal morphology using the CBCT.MATERIAL AND METHODS: For this bibliometric analysis, an extensive search was carried out on September 25, 2023 using the Scopus database. Pertinent articles in the field were scrutinized after applying inclusion and exclusion criteria. Data were evaluated using Vosviewer and Microsoft Excel.
    RESULTS: A literature search revealed the initiation of scientific publication in 2008. Significant contributions made by Saudi Arabia, India, and China concerning the number of publications were seen. Similarly, Jazan University from SA was recognized as the leading institute. The Journal of Endodontics was the leading journal, while authors JNR Martins and G Gambarini produced the highest number of papers.
    CONCLUSIONS: This bibliometric analysis demonstrated that scientific publications have increased tremendously since 2008. Significant contributions have been made by developing and developed nations. The Journal of Endodontics and Jazan University have been identified as the leading journal and institute.
    Keywords:  dental anatomy; dental diagnostic imaging; dental pulp; endodontics
    DOI:  https://doi.org/10.1002/cre2.801
  18. Altern Ther Health Med. 2023 Oct 27. pii: AT9672. [Epub ahead of print]
      Objectives: Utilizing Bibliometric Analysis to Evaluate Research Trends in Factors Influencing Respiratory System Diseases Among University Students and Investigate Institutional Collaborations, Research Hotspots, and Emerging Trends.Methodology: A computer-based retrieval process was employed to access publications from the Web of Science and the China National Knowledge Infrastructure (CNKI) databases. This retrieval encompassed articles published in both Chinese and English languages, spanning from January 1, 1998, to June 1, 2023, focusing on the impact factors of respiratory system diseases among university students. Subsequently, a visual analysis was conducted using bibliometric software known as CiteSpace, exploring the dimensions of nations, institutions, journals, authors, cited references, and keywords.
    Results: A total of 927 scholarly papers pertaining to the determinants of respiratory system diseases among university students were retrieved. Of these, 667 were published in English, while 260 were in Chinese. The volume of publications in this field has exhibited a steady annual increase, with a notable exponential surge observed in 2019 concerning research output on respiratory system diseases among university students. However, there was a subsequent decline in publication volume by the year 2023. Key terms such as "Air pollution," "attitude," "lifestyle," and "infectious laryngotracheitis virus" have emerged as prominent nodes, signifying their critical relevance in shaping the forefront of research on respiratory system diseases among university students. Moreover, "attitude" and "lifestyle" have exhibited a sustained presence over an extended timeline.In recent years, keywords such as "COVID-19" and "health" have gained prominence and maintained persistent scholarly attention. This phenomenon underscores their status as current research hotspots and frontiers in the study of respiratory system diseases among university students. Noteworthy terms include "COVID-19," "coronavirus diseases 19," "exposure," "asthma," and "health."
    Conclusion: School food safety and hygiene issues, students' lifestyle and attitudes, along with the impact of "COVID-19," constitute prominent research focal points and trends in the investigation of causative factors of respiratory system diseases among university students. The findings from bibliometric analysis furnish valuable insights for researchers, aiding in the identification of potential collaborators and institutions. Additionally, they facilitate the exploration of key issues within this domain and the pursuit of novel research directions.
  19. Endocr Metab Immune Disord Drug Targets. 2023 Oct 20.
      BACKGROUND: Osteoporosis (OP) is a systemic bone metabolism disorder in which the immune system and bone metabolism interact.OBJECTIVE: The purpose of this study was to explore the research status, hot spots and trends regarding the influence of the immune system on OP and to provide a basis for research directions and applications in this field.
    METHODS: We searched and collected literature about the immune system and OP published from 2012 to 2022 in the Web of Science Core Collection database. All the included studies were subjected to bibliometrics analysis using Hiplot Pro, VOSviewer and CiteSpace software to produce statistics and visual analyses of the literature output, countries, institutions, authors, keywords and journals.
    RESULTS: A total of 1201 papers were included, and the number of citations of these articles reached 31,776. The number of publications and citations on the immune system and OP has increased year by year. The top three countries with the greatest number of papers published were China, the United States of America (USA) and Italy. The two institutions with the largest number of papers published were Sichuan University and Soochow University, both located in China. De Martinis Massimo (Italy) and Ginaldi Lia (Italy) are prolific authors in this field. The representative academic journals are Osteoporosis International, Frontiers in Immunology, Journal of Bone and Mineral Research, PloS One and Bone. The results of the keyword cooccurrence analysis showed that the research topics in this field mainly focused on T cells, cytokines, signaling pathways, vitamin D, postmenopausal OP and immune diseases. The keyword burst results showed that zoledronic acid, chain fatty acids and gut microbiota are the frontiers and trends of future research on this topic.
    CONCLUSION: The influence of the immune system on OP has been widely studied, and the current research in this field focuses on the effect or mechanism of immune-related cytokines, signaling pathways and vitamin D on OP. Future research trends in this field should focus on the immune regulation mechanism and clinical transformation of zoledronic acid, chain fatty acids and the gut microbiota in OP.
    Keywords:  bibliometrics; bone metabolism; immune system; osteoporosis; visualizatioimmune system; visualization
    DOI:  https://doi.org/10.2174/0118715303257269231011073100
  20. Quant Imaging Med Surg. 2023 Oct 01. 13(10): 7117-7141
      Background: Indocyanine green (ICG) fluorescence navigation can enhance the visualization of gastric cancer (GC) lesions, increase the lymph node detection rate, and reduce the incidence of anastomotic leakage in the treatment of GC. It thus holds considerable potential for application in GC clinical surgery and has attracted widespread research interest. The purpose of this study was to visualize the current topics and emerging trends in research regarding ICG in GC.Methods: We searched the Web of Science Core Collection (WoSCC) for articles relevant to the use of ICG in GC. The resulting information was then analyzed from a bibliometric and knowledge graph analysis perspective using CiteSpace, Scimago Graphica, and R Studio so that the key trends and hot spots in research within this field could be identified and visualized.
    Results: Ultimately, 1,385 papers from 58 countries or regions published from 1991 to 2022 were included in this study. The largest number of publications were from China, followed by Japan and the United States. High-yield institutions were concentrated in Asian countries, especially China. The top publication contributors were Shanghai Jiao Tong University. Li Y and Bang YJ ranked first among the top 10 most productive authors and top 10 most cocited authors, respectively. World Journal of Gastroenterology was the most productive academic journal on ICG in GC, while Cancer Research was the most commonly cocited journal. The keyword "indocyanine green" was among the top 5 keywords, and will likely remain a popular topic in future research. Furthermore, the emerging themes including surgery, biopsy, lymphadenectomy, dissection, and gastrectomy have attracted increasing attention.
    Conclusions: Current research hotspots in this area focus on the clinical implementation of ICG in precision surgery for GC. Given the imaging tracer characteristics of ICG and its utility in GC surgery, the optimization and application of ICG-guided precision surgery techniques for GC will be a research hot spot going forward.
    Keywords:  CiteSpace; Indocyanine green (ICG); Web of Science (WoS); bibliometric analysis; gastric cancer (GC)
    DOI:  https://doi.org/10.21037/qims-23-391
  21. Environ Sci Pollut Res Int. 2023 Oct 21.
      Silicosis is a global disease whose prevention efforts cannot be ignored today. Although numerous silicosis-related data have been published recently, emphasizing the characteristics and nature of silicosis, a summary of the developmental laws of research is lacking, especially in the visual analysis of the literature. We aim to address this issue through a scientometric review. The Web of Science Core Collection and the All Databases were searched with "silicosis" as the topic, excluding unrelated publications, and obtained data from 9802 and 1613 publications, respectively. The data was then analyzed using the Web of Science's online scientometric analysis function and CiteSpace's visual analysis functionality, including publication volume analysis, co-occurrence analysis, co-citation analysis, cluster analysis, and explosive detection. The results identify the "respiratory system" as the most influential area over a century. Furthermore, the publication's number was correlated with the gross domestic product. We ranked countries and institutions based on the frequency of publications and discovered that Europe, the USA, and China are the leading regions for silicosis research, with the USA and Europe having a stronger influence. Many reports related to artificial stone and denim jean production have been studied through citation analysis, indicating new epidemic trends in silicosis. Besides, silicosis-related diseases and the pathogenesis of silicosis were the research hotspots of silicosis through co-occurrence keyword analysis and outbreak detection. Furthermore, related diseases include coal workers' pneumoconiosis and tuberculosis, while the mechanism of silicosis includes studies on inflammation and fibrosis, oxidative stress, alveolar macrophages, apoptosis, and pathways.
    Keywords:  CiteSpace; Epidemic; Fibrosis; Related diseases; Silicosis; Visualization analysis
    DOI:  https://doi.org/10.1007/s11356-023-30418-7
  22. Quant Imaging Med Surg. 2023 Oct 01. 13(10): 6761-6777
      Background: Prostate cancer (PCa) is the most common tumor of the male genitourinary system. With the development of imaging technology, the role of magnetic resonance imaging (MRI) in the management of PCa is increasing. The present study summarizes research on the application of MRI in the field of PCa using bibliometric analysis and predicts future research hotspots.Methods: Articles regarding the application of MRI in PCa between January 1, 1984 and June 30, 2022 were selected from the Web of Science Core Collection (WoSCC) on November 6, 2022. Microsoft Excel 2016 and the Bibliometrix Biblioshiny R-package software were used for data analysis and bibliometric indicator extraction. CiteSpace (version 6.1.R3) was used to visualize literature feature clustering, including co-occurrence analysis of countries, institutions, authors, references, and burst keywords analysis.
    Results: A total of 10,230 articles were included in the study. Turkbey was the most prolific author. The USA was the most productive country and had strong partnerships with other countries. The most productive institution was Memorial Sloan Kettering Cancer Center. Journal of Magnetic Resonance Imaging and Radiology were the most productive and highest impact factor (IF) journals in the field, respectively. Timeline views showed that "#1 multiparametric magnetic resonance imaging", "#4 pi-rads", and "#8 psma" were currently the latest research hotspots. Keywords burst analysis showed that "machine learning", "psa density", "multi parametric mri", "deep learning", and "artificial intelligence" were the most frequently used keywords in the past 3 years.
    Conclusions: MRI has a wide range of applications in PCa. The USA is the leading country in this field, with a concentration of highly productive and high-level institutions. Meanwhile, it can be projected that "deep learning", "radiomics", and "artificial intelligence" will be research hotspots in the future.
    Keywords:  CiteSpace; Prostate cancer (PCa); bibliometric; magnetic resonance imaging (MRI)
    DOI:  https://doi.org/10.21037/qims-23-446
  23. Injury. 2023 Oct 11. pii: S0020-1383(23)00830-6. [Epub ahead of print] 111116
      BACKGROUND: Motor impairment is a significant health concern among post-stroke patients. Transcranial magnetic stimulation (TMS) is considered as an emerging rehabilitation therapy for various neurological conditions, and the effects of excitatory TMS on post-stroke have received much attention in past decade. However, the future hotspots and content analysis on the growth trends have not been studied. This bibliometric and content analysis aimed to study the global developmental history and current status of TMS for motor function of post-stroke from January 2004 to July 2023.METHODS: Literature published on Scopus database from January 2004 to July 2023 were searched. Extracted data was analysed using the R studio and VOS viewer for author's publication, institutions, sources, keyword co-occurrence and world network analysis. Keyword cluster analysis, co-citation analysis for references and content analysis were also performed. We screened top 10 most cited or collaborative areas for publications, institutions and sources in the field of TMS associated with motor function of post-stroke.
    RESULTS: In this study, a comprehensive analysis of 267 publications was conducted, revealing a substantial surge in research output throughout 2022. China emerged as the leading contributor, with 409 publications, followed by the United States with 211 publications. Notably, Harvard Medical School stood out as one of the most prolific institutions, accounting for 34 publications (13.12 %). Among researchers, Abo M garnered the highest publication count, with 9 articles (14.5 %). The Word cloud showed that motor function, repetitive transcranial magnetic stimulation (rTMS) and upper limb have been the focus of recent attention. Burst keywords on thematic evolution and topic trend shows that quality of life scale, network parameters, cognition, lower limb motor function are the future trends.
    CONCLUSION: This bibliometric study describes that TMS has shown promising results in improving motor function of upper extremity in stroke patients, the long-term effects and durability of these improvements are still being investigated. Future research might focus on understanding the optimal duration and frequency of TMS sessions for sustained motor recovery and exploring strategies to maintain gains achieved through TMS over extended periods of time. Future studies can investigate the changes in the lower limb motor function.
    Keywords:  Lower limb; Motor function; Stroke; Transcranial magnetic stimulation; Upper limb
    DOI:  https://doi.org/10.1016/j.injury.2023.111116
  24. Asian J Surg. 2023 Oct 23. pii: S1015-9584(23)01646-9. [Epub ahead of print]
      
    Keywords:  Artificial intelligence; Bibliometric analysis; ChatGPT; Surgery
    DOI:  https://doi.org/10.1016/j.asjsur.2023.10.034
  25. Eur J Med Res. 2023 Oct 27. 28(1): 461
      Breast cancer, as a daunting global health threat, has driven an exponential growth in related research activity in recent decades. An area of research of paramount importance is protein synthesis, and the analysis of specific proteins inextricably linked to breast cancer. In this article, we undertake a bibliometric analysis of the literature on breast cancer and protein synthesis, aiming to provide crucial insights into this esoteric realm of investigation. Our approach was to scour the Web of Science database, between 2003 and 2022, for articles containing the keywords "breast cancer" and "protein synthesis" in their title, abstract, or keywords. We deployed bibliometric analysis software, exploring a range of measures such as publication output, citation counts, co-citation analysis, and keyword analysis. Our search yielded 2998 articles that met our inclusion criteria. The number of publications in this area has steadily increased, with a significant rise observed after 2003. Most of the articles were published in oncology or biology-related journals, with the most publications in Journal of Biological Chemistry, Cancer Research, Proceedings of the National Academy of Sciences of the United States of America, and Oncogene. Keyword analysis revealed that "breast cancer," "expression," "cancer," "protein," and "translation" were the most commonly researched topics. In conclusion, our bibliometric analysis of breast cancer and related protein synthesis literature underscores the burgeoning interest in this research. The focus of the research is primarily on the relationship between protein expression in breast cancer and the development and treatment of tumors. These studies have been instrumental in the diagnosis and treatment of breast cancer. Sustained research in this area will yield essential insights into the biology of breast cancer and the genesis of cutting-edge therapies.
    Keywords:  Bibliometric analysis; Breast cancer; Protein synthesis
    DOI:  https://doi.org/10.1186/s40001-023-01364-4
  26. Animals (Basel). 2023 Jun 01. pii: 1839. [Epub ahead of print]13(11):
      Somatic cell nuclear transfer (SCNT) is a reproductive biotechnology with great potential in the reproduction of different species of zootechnical interest, including sheep. This study aimed to carry out a bibliometric analysis of scientific papers published on the application of SCNT in sheep reproduction during the period 1997-2023. The search involved the Science Citation Index Expanded and Social Sciences Citation Index databases of the main collection of the Web of Sciences with different descriptors. A total of 124 scientific papers were analyzed for different bibliometric indicators using the VOSviewer software. Since 2001, the number of SCNT-related papers that have been published concerning sheep reproduction has increased and it has fluctuated in ensuing years. The main authors, research groups, institutions, countries, papers, and journals with the highest number of papers related to the application of SCNT in sheep reproduction were identified, as well as the topics that address the research papers according to the terms: somatic cell, embryo, oocyte, gene expression, SCNT, and sheep.
    Keywords:  SCNT; VOSviewer; bibliometric analysis; nuclear transfer; reproductive biotechnology; sheep
    DOI:  https://doi.org/10.3390/ani13111839
  27. J Pain Res. 2023 ;16 3441-3462
      Background: Biomechanical research on the lumbar intervertebral disc (IVD) provides valuable information for the diagnosis, treatment, and prevention of related diseases, and has received increasing attention. Using bibliometric methods and visualization techniques, this study investigates for the first time the research status and development trends in this field, with the aim of providing guidance and support for subsequent research.Methods: The Science Citation Index Expanded (SCI-Expanded) within the Web of Science Core Collection (WoSCC) database was used as the data source to select literature published from 2003 to 2022 related to biomechanical research on lumbar IVD. VOSviewer 1.6.19 and CiteSpace 6.2.R2 visualization software, as well as the online analysis platform of literature metrology, were utilized to generate scientific knowledge maps for visual display and data analysis.
    Results: The United States is the most productive country in this field, with the Ulm University making the largest contribution. Wilke HJ is both the most prolific author and one of the highly cited authors, while Adams MA is the most cited author. Spine, J Biomech, Eur Spine J, Spine J, and Clin Biomech are not only the journals with the highest number of publications, but also highly cited journals. The main research topics in this field include constructing and validating three-dimensional (3D) finite element model (FEM) of lumbar spine, measuring intradiscal pressure, exploring the biomechanical effects and related risk factors of lumbar disc degeneration, studying the mechanical responses to different torque load combinations, and classifying lumbar disc degeneration based on magnetic resonance images (MRI), which are also the hot research themes in recent years.
    Conclusion: This study systematically reviews the knowledge system and development trends in the field of biomechanics of lumbar IVD, providing valuable references for further research.
    Keywords:  CiteSpace; VOSviewer; bibliometric; biomechanics; lumbar intervertebral disc; visualization analysis
    DOI:  https://doi.org/10.2147/JPR.S428991
  28. Gut Pathog. 2023 Oct 25. 15(1): 50
      BACKGROUND: Children with autism spectrum disorder (ASD) often have digestive problems and microbial imbalances in their guts, suggesting that these conditions may play a role in the development of the disorder. Scopus-based research on the gut microbiota and ASD was examined in this bibliometric analysis to shed light on the current state of research and identify potential hotspots for future work in this area.METHODS: We searched documents from the Scopus database and reference citation analysis to collect published data on the gut microbiota and ASD from 2003 to 2022. The downloaded document records were exported to VOSviewer v.1.6.19 to examine and visualize the collaboration between countries and determine the research hotspots.
    RESULTS: The search yielded 958 articles specifically dedicated to gut microbiota and ASD. The number of publications in this field increased rapidly after 2013, with a peak in 2022. The United States (n = 267; 27.87%) was the most active country, followed by China (n = 171; 17.85%) and Italy (n = 96; 10.02). International collaboration was observed, with the USA playing a central role. University College Cork, Ireland, was the most productive institution (n = 24; 2.51%). The National Natural Science Foundation of China was the most active funding agency (n = 76; 7.93%). Nutrients journal had the highest number of publications (n = 28; 2.92%). The articles related to gut microbiota and ASD were highly cited, with an h-index of 108. The research themes identified focused on the modulation of gut microbiota as a potential therapy for children with ASD and gut-brain axis dysfunction in ASD.
    CONCLUSIONS: In recent years, the study of gut microbiota and its association with ASD has garnered considerable interest as an emergent field of study. The results of this study substantially enhance our current understanding of the knowledge landscape in this field and illuminate potential avenues for future research. It is essential to emphasize the significance of devoting more resources to the newest and most promising research areas, such as investigating the potential therapeutic benefits of modulating the intestinal microbiota in children with ASD. This research has enormous potential and merits intensified focus and investigation.
    Keywords:  ASD; Autism; Autism spectrum disorders; Bibliometric; Gut microbiota; Reference citation analysis; Scopus
    DOI:  https://doi.org/10.1186/s13099-023-00575-8
  29. Ren Fail. 2023 ;45(2): 2270061
      Diabetic kidney disease (DKD) is a severe complication of diabetes mellitus (DM). The literature on DKD inflammation research has experienced substantial growth. However, there is a lack of bibliometric analyses. This study aimed to examine the existing research on inflammation in DKD by analyzing articles published in the Web of Science Core Collection (WOSCC) over the past 30 years. We conducted a visualization analysis using several software, including CiteSpace and VOSviewer. We found that the literature on inflammation research in DKD has experienced substantial growth, indicating a rising interest in this developing area of study. In this field, Navarro-Gonzalez, JF is the most frequently cited author, Kidney International is the most frequently cited journal, China had the highest number of publications in the field of DKD inflammation, and Monash University emerged as the institution with the most published research. The research area on inflammation in DKD primarily centers around the investigation of 'Glycation end-products', 'chronic kidney disease', and 'diabetic nephropathy'. The emerging research trends in this field will focus on the 'Gut microbiota', 'NLRP3 inflammasome', 'autophagy', 'pyroptosis', 'sglt2 inhibitor', and 'therapeutic target'. Future research on DKD may focus on further exploring the inflammatory response, identifying specific therapeutic targets, studying biomarkers, investigating stem cell therapy and tissue engineering, and exploring gene therapy and gene editing. In summary, this study examines the main areas of study, frontiers, and trends in DKD inflammation, which have significant implications for future research.
    Keywords:  Bibliometric analysis; diabetic kidney disease; inflammation; research trends
    DOI:  https://doi.org/10.1080/0886022X.2023.2270061
  30. Front Immunol. 2023 ;14 1242336
      Background: Immune checkpoint inhibitors (ICIs) has emerged as a popular cancer treatment approach. However, non-specific activation of T cells by ICIs can lead to immune-related adverse events (irAEs), including specific rheumatic manifestations. The study aimed to explore the current trend of ICIs associated rheumatic irAEs and summarize the knowledge structure through bibliometric methods.Methods: The Web of Science Core Collection database (WoSCC) was selected for retrieving literature on ICIs associated rheumatic irAEs. To evaluate contributions from different countries/regions, institutions, journals, and authors, bibliometric analysis software, including VOSviewer and CiteSpace, as well as bibliometric online platforms, were utilized to construct and visualize bibliometric networks. Through the systematic review of this knowledge domain, future research directions were determined.
    Results: In This study, a total of 803 publications on ICIs-associated rheumatic irAEs were included for analysis. The distribution of these publications revealed two distinct growth phases: a stable phase between 2007 to 2015 followed by rapid growth from 2016 to 2020. The United States emerged as the top contributor in terms of publications, citations, and h-index, with the majority of leading institutions and funding agencies located there. Apart from government funding, pharmaceutical companies such as Bristol Myers Squibb and Merck Company also play a significant role in drug development and research. Analysis of keywords and citation bursts indicated that the initial burst was related to "monoclonal antibody," "anti-CLTA4 antibody," and "melanoma". This was followed by a rise in interest related to "sarcoidosis," "safety," "inflammatory arthritis," and "preexisting autoimmune."
    Conclusion: This study summarized the global research trends concerning ICIs associated rheumatic irAEs. The findings can provide valuable insights into the current understanding of rheumatic irAEs, highlight the research trend and developments in the field. Future efforts should focus on developing classification criteria and guidelines, conducting prospective studies, investigating the mechanisms involved, and identifying biomarkers for prediction and monitoring of these events.
    Keywords:  CiteSpace; VOSviewer; bibliometric; immune checkpoint inhibitor; research trends; rheumatic immune-related adverse event
    DOI:  https://doi.org/10.3389/fimmu.2023.1242336
  31. Heliyon. 2023 Nov;9(11): e21289
      Background: Occupational exposure is of increasing concern, posing a serious threat to nurses, especially in the event of a public health emergency. Bibliometrics sheds novel light on the current state of research and factors influencing nurses' occupational exposures, illuminating hot topics and trends in the literature. Bibliometrics is essential to analyze the potential harm to nurses in Asia.Methods: Data were extracted from the Web of Science Core Collection on August 6, 2022 with the following search terms: TS= (nurses) AND (TS= (occupational exposure OR occupational health)). CiteSpace and VOSviewer were used to analyze national and institutional collaborations, reference clustering, citations and co-citations of journals and keyword bursts, and HistCite was used to analyze the citation historiography map. To analyze the data and generate statistical charts, Origin and Microsoft Excel were utilized.
    Results: A total of 1448 studies on nurses' occupational exposure in Asia were identified. China Medical University had the most publications among Asian institutions, and China had the largest share among Asian countries. Most articles on nurses' occupational exposure in Asia were in the Journal of Occupational Health, and the journal with the highest impact factor was the Journal of Nursing Management. The COVID-19 outbreak caused a substantial shift in the direction of studies on nurses' occupational exposure in Asia. Mental health is a current hot topic, while sharps injuries and bodily fluid exposure are long-term priorities for attention.
    Conclusions: The hotspots of research on nurses' occupational exposure in Asia focus on mental health, burnout, blood exposure, infection, and sharps injury. Due to the COVID-19 pandemic, recent research has concentrated on personalized mental health care and the development of protective equipment, and cross-disciplinary collaboration may be a new trend in the future.
    Keywords:  Asia; Bibliometric analysis; Nurses; Nursing research; Occupational exposure
    DOI:  https://doi.org/10.1016/j.heliyon.2023.e21289
  32. Hum Vaccin Immunother. 2023 Dec 15. 19(3): 2269794
      This study aims to summarize and visually analyze the current research status in pancreatic cancer immunotherapy during the past two decades by bibliometrics and explore the current research hotspots and future development directions. The literature related to pancreatic cancer immunotherapy from 2002 to 2021 was downloaded from the core database of the Web of Science. VOSviewer and CiteSpace software were used to visualize the included literature. A total of 2528 articles were included. In the past two decades, publications in the pancreatic cancer immunotherapy field have increased almost annually. As the country with the largest publications, the United States has various research institutions dedicated to pancreatic cancer immunotherapy. Jaffee EM and Zheng L from Johns Hopkins University and Vonderheide RH from the University of Pennsylvania have published the most articles in this field. The current research hotspots of pancreatic cancer immunotherapy include the tumor microenvironment, immune cells, immune checkpoint blockade, and combination therapy. The study of novel immunotherapies and combination therapy may become the primary focus of future research on pancreatic cancer immunotherapy. More prospective clinical studies with high evidence levels should be conducted.
    Keywords:  Pancreatic cancer; bibliometrics; immunotherapy; visual analysis
    DOI:  https://doi.org/10.1080/21645515.2023.2269794
  33. Int J Environ Res Public Health. 2023 Oct 10. pii: 6905. [Epub ahead of print]20(20):
      The residential environment's impact on aging in place is a multidisciplinary field that draws from architecture, urban planning, gerontology, psychology, and sociology. This multidisciplinary nature makes it challenging to comprehensively understand the field and identify the connections and interactions among disciplines. A bibliometric analysis is crucial for exploring the field's intellectual structure, identifying interdisciplinary collaborations, and tracking the knowledge flow across disciplines and will facilitate cross-disciplinary dialogue, foster collaboration, and encourage research that integrates diverse perspectives. This study reviewed the literature on aging in place in the context of a residential environment, which required adapting theories and methodologies. It analyzed a dataset of 1500 publications retrieved from the Web of Science, applied performance analysis techniques, and utilized VOSviewer to visualize the intellectual structure and evolving research themes. The results emphasize the increasing strength of academic interest and the growing diversity of fields related to the topic. The findings are discussed in terms of productivity, collaboration, and research themes from the past to the future. The results provide a roadmap for researchers, policymakers, and practitioners worldwide who focus on aging in place and acknowledge the importance of considering the physical, social, and cultural aspects of an older adult's living environment.
    Keywords:  aging at home; aging in community; aging in place; bibliometric analysis; residential environments
    DOI:  https://doi.org/10.3390/ijerph20206905
  34. RSC Adv. 2023 Oct 18. 13(44): 30704-30717
      As a powerful tool for biological sensing, electrochemical biosensors have attracted much attention due to their ability to integrate biological recognition elements on an electrochemical interface and convert target analyte information into measurable electrochemical signals. Despite the abundance of literature published on the topic, no comprehensive surveys have been conducted to evaluate the area of electrochemical biosensors with bibliometric techniques. This paper employs VOSviewer to analyze and visualize literature from 2003 to 2023 in the Web of Science in order to gain an understanding of the development of the field of electrochemical biosensors in recent years. Co-occurrence and co-citation analysis are employed to identify research hotspots, trace evolutionary paths, and comprehend development trends in the field. Moreover, by analyzing highly cited and representative literature from different time periods, it is possible to recognize the major research hotspots and grasp the development pulse. The results of this study provide a comprehensive overview of the field of electrochemical biosensors and can be used to guide future research.
    DOI:  https://doi.org/10.1039/d3ra05889a
  35. Heliyon. 2023 Oct;9(10): e20856
      Purpose: This study aimed to conduct a bibliometric analysis of the data acquired and clarified the current research status of sexual health problems in patients with cancer, to provide a comprehensive visual perspective suitable as a reference for subsequent research.Methods: We searched the Web of Science Core Collection (WoSCC) up to April 30, 2023 to identify studies associated with sexual health problems in patients with cancer. CiteSpace was used to create visualization networks for countries, institutions, authors, and journals.
    Results: A total of 3183 publications related to sexual health problems in patients with cancer were collected from the WoSCC. In terms of volume, the USA (1259 papers) was the leading country, the Memorial Sloan Kettering Cancer Center (119 papers) was the leading institution, and Carter (39 papers) was the author with the most publications. The top-cited references and keywords were related to quality of life. The top five clusters of reference cocitation were 'brachytherapy', 'prostate cancer', 'radical prostatectomy', 'hypogonadism', and 'breast cancer'. Meanwhile, the top five clusters of keyword cocitation were 'breast cancer', 'prostate cancer', 'rectal cancer', 'testicular cancer', and 'sexual function'. The analysis of the top 25 references and keywords with the strongest citation bursts of published papers on sexual health problems in patients with cancer to reveal the research hotspots and trends.
    Conclusions: Research on sexual health among patients with cancer is constantly developing. The current research focuses on the impact of different treatment options for sexual health and quality of life of patients with breast, rectal, and genitourinary neoplasms. Exploring the long-term changing regularities of sexual function among cancer survivors and formulating sexual health interventions toward patient-reported outcomes and needs are key research directions.
    Keywords:  Bibliometrics; CiteSpace; Patients with cancer; Sexual health; Visualization analysis
    DOI:  https://doi.org/10.1016/j.heliyon.2023.e20856
  36. Sensors (Basel). 2023 Oct 11. pii: 8384. [Epub ahead of print]23(20):
      In recent years, unmanned aerial vehicles (UAVs) have been increasingly used to monitor and assess air quality. The interest in the application of UAVs in monitoring air pollutants and greenhouse gases is evidenced by the recent emergence of sensors with the most diverse specifications designed for UAVs or even UAVs designed with integrated sensors. The objective of this study was to conduct a comprehensive review based on bibliometrics to identify dynamics and possible trends in scientific production on UAV-based sensors to monitor air quality. A bibliometric analysis was carried out in the VOSViewer software (version 1.6.17) from the Scopus and Web of Science reference databases in the period between 2012 and 2022. The main countries, journals, scientific organizations, researchers and co-citation networks with greater relevance for the study area were highlighted. The literature, in general, has grown rapidly and has attracted enormous attention in the last 5 years, as indicated by the increase in articles after 2017. It was possible to notice the rapid development of sensors, resulting in smaller and lighter devices, with greater sensitivity and capacity for remote work. Overall, this analysis summarizes the evolution of UAV-based sensors and their applications, providing valuable information to researchers and developers of UAV-based sensors to monitor air pollutants.
    Keywords:  air pollutants; drones; greenhouse gases; particulate matter; sensors
    DOI:  https://doi.org/10.3390/s23208384
  37. Int J Environ Res Public Health. 2023 Oct 20. pii: 6951. [Epub ahead of print]20(20):
      In recent decades, health literacy has garnered increasing attention alongside a variety of public health topics. This study aims to explore trends in this area through a bibliometric analysis. A Random Forest Model was utilized to identify keywords and other metadata that predict average citations in the field. To supplement this machine learning analysis, we have also implemented a bibliometric review of the corpus. Our findings reveal significant positive coefficients for the keywords "COVID-19" and "Male", underscoring the influence of the pandemic and potential gender-related factors in the literature. On the other hand, the keyword "Female" showed a negative coefficient, hinting at possible disparities that warrant further investigation. Additionally, evolving themes such as COVID-19, mental health, and social media were discovered. A significant change was observed in the main publishing journals, while the major contributing authors remained the same. The results hint at the influence of the COVID-19 pandemic and a significant association between gender-related keywords on citation likelihood, as well as changing publication strategies, despite the fact that the main researchers remain those who have been studying health literacy since its creation.
    Keywords:  COVID-19; bibliometric analysis; health literacy; public health; random forest
    DOI:  https://doi.org/10.3390/ijerph20206951
  38. Cureus. 2023 Sep;15(9): e45820
      Thyroid diseases are diverse, ranging from benign conditions to potentially life-threatening disorders. Recently, the application of artificial intelligence (AI) in evaluating thyroid disease has significantly enhanced medical research, diagnosis prediction, and algorithm development. Coupled with this advancement is the rising focus on the importance of gender equality in scientific publications. This study delves into the gender trends of first authors in papers related to "Artificial Intelligence and Thyroid" sourced from PubMed from 2003 to 2022, scrutinizing these trends based on both country and year. A bibliometric analysis was conducted on PubMed to retrieve relevant articles over this 19-year time span. Following this, the names and affiliated countries of the first authors were determined. The Namsor app, a tool for classifying personal names by gender, origin, or ethnicity, was then used to segregate the data based on gender. Statistical analyses were performed using the R software- ARIMA model and Fisher's exact test was applied to examine the correlations between gender and country of origin. From the 254 analyzed articles, 43.5% of the first authors were female, while 56.69% were male. The year 2022 saw the most significant number of female first-author publications. Intriguingly, the European Journal of Radiology was prominent due to its favorable gender ratio. Moreover, the association between gender and country was significant, with China being a standout. Limitations included focusing only on PubMed journals and using a third party for gender identification. Nevertheless, the study reveals a move toward gender parity in AI and thyroid research over the past 18 years, emphasizing the importance of sustained efforts for academic inclusivity.
    Keywords:  artificial intelligence; first author; gender equality; pubmed; thyroid
    DOI:  https://doi.org/10.7759/cureus.45820
  39. Curr Neuropharmacol. 2023 Sep 28.
      We conducted a scientometric analysis to outline clinical research on posttraumatic stress disorder (PTSD). Our primary objective was to perform a broad-ranging scientometric analysis to evaluate key themes and trends over the past decades. Our secondary objective was to measure research network performance. We conducted a systematic search in the Web of Science Core Collection up to 15 August 2022 for publications on PTSD. We identified 42,170 publications published between 1945 and 2022. We used CiteSpace to retrieve the co-cited reference network (1978-2022) that presented significant modularity and mean silhouette scores, indicating highly credible clusters (Q = 0.915, S = 0.795). Four major trends of research were identified: 'war veterans and refugees', 'treatment of PTSD/neuroimaging', 'evidence syntheses', and 'somatic symptoms of PTSD'. The largest cluster of research concerned evidence synthesis for genetic predisposition and environmental exposures leading to PTSD occurrence. Research on war-related trauma has shifted from battlefield-related in-person exposure trauma to drone operator trauma and is being out published by civilian-related trauma research, such as the 'COVID-19' pandemic impact, 'postpartum', and 'grief disorder'. The focus on the most recent trends in the research revealed a burst in the 'treatment of PTSD' with the development of Mhealth, virtual reality, and psychedelic drugs. The collaboration networks reveal a central place for the USA research network, and although relatively isolated, a recent surge of publications from China was found. Compared to other psychiatric disorders, we found a lack of high-quality randomized controlled trials for pharmacological and nonpharmacological treatments. These results can inform funding agencies and future research.
    Keywords:  CiteSpace.; Trauma; bibliometric; evidence synthesis; neuroimaging; stress
    DOI:  https://doi.org/10.2174/1570159X22666230927143106
  40. J Community Psychol. 2023 Oct 21.
      There have been multiple efforts to evaluate the contributions of the field of Community Psychology, and one of the more popular methods has involved gathering citations and articles published in Community Psychology journals. In recent years, several sites have gathered citation analysis and article publication rates so that it is now relatively easy to summarize settings and scholar rankings. In the current study, articles published in the two major journals of the field of Community Psychology over the past five decades were evaluated for these publications and citations. Findings indicated that several of the settings with highest publication and citation rates have not developed Community Psychology graduate programs, thus indicating that many publishing authors are in settings without formal graduate programs in Community Psychology. The benefits and limitations of this method of ranking programs and individuals are reviewed.
    Keywords:  American Journal of Community Psychology; Journal of Community Psychology; articles; citations
    DOI:  https://doi.org/10.1002/jcop.23094
  41. Cureus. 2023 Sep;15(9): e45695
      Introduction Artificial intelligence (AI) and cardiovascular diseases have resulted in significant advancements in healthcare and medical research. This study focused on examining the gender equality ratio of first authors in "artificial intelligence and cardiovascular disease" articles from 2005 to 2022. It is critical to investigate gender representation in this dynamic subject given the growing usage of AI in cardiovascular medicine. Aims The aim of this study is to visualize the changing face of gender equality within the field of artificial intelligence (AI) and cardiovascular diseases by examining the gender distribution of the first authors' published articles from 2005 to 2022, providing important insights into disparities in gender and the potential for fostering inclusivity and diversity in the scientific community. Methodology All academic articles published from 2005 to 2022 were reviewed. The gender of the first author of each study was recorded. Since there were so few articles available for five months in 2023, they were excluded. The research was subsequently categorized based on the gender, ethnicity, and country of origin of the first authors. Results With a value of 0.54, the overall gender ratio favored male authors (275) over female authors (149). In 2022, female first authors had the most publications (59), while male first authors contributed 113 articles. Predictions for 2027 showed a significant increase in the number of publications on this topic by male authors (950) and female authors (580). A gradual increase in the number of female first authors was observed over this period, although their representation remained lower compared to male first authors. Conclusions In the first authorship, our analysis found a gender gap, with male authors predominating. Females' engagement must be encouraged if academic gender equality is to be achieved. Female researchers are empowered by creating an inclusive atmosphere through mentorship and regulatory changes. For knowledge to advance fairly, collaboration is essential.
    Keywords:  ai and cardiovascular disease; female; gender equality; pubmed; research
    DOI:  https://doi.org/10.7759/cureus.45695
  42. Sci Total Environ. 2023 Oct 24. pii: S0048-9697(23)06743-8. [Epub ahead of print] 168116
      Emerging contaminants (ECs) have attracted increasing attention in the past two decades because of their ubiquitous existence and high environmental risk. Understanding the progress of research and the evolution of hot topics is critical. This study provides a bibliometric review, along with a quantitative trend analysis of approximately 8000 publication records dated from 2001 to 2021. Wider distribution in various subjects was discovered in terms of publication numbers, indicating a strong tendency for EC research to become an interdisciplinary topic. Visualization of term co-occurrence analysis revealed that the ECs study went through three stages over time: identification and detection, traceability and risk, and process and control. Quantitative trend analysis revealed that antibiotics, microplastics, endocrine disrupting chemicals (EDCs), per/poly-fluoroalkyl substances (PFAS), pesticides, heavy metals, and nanoparticles are attracting increasing attention, whereas conventional pharmaceuticals, persistent organic pollutants, and materials such as benzotriazole, diclofenac, bisphenol A, carbamazepine, triclosan, and titanium dioxide exhibit a downward trend. PFAS and EDCs are considered potential future core hotspots for the hysteretic rise in research attention compared with conventional ECs. Furthermore, analysis of research linkage and the developing stages of ECs could be possible approach to determine the evolution of hotspots in ECs study. This study provides objective and comprehensive insights into the research landscape of ECs, which may shed light on future developmental directions for researchers interested in this field.
    Keywords:  Bibliometric analysis; Emerging contaminants; Hotspot evolution; Research stage; Thematic network; Trend analysis
    DOI:  https://doi.org/10.1016/j.scitotenv.2023.168116
  43. Biomed Res Int. 2023 ;2023 2385018
      Introduction: Candida auris is a relatively novel pathogen first described in 2009 in Japan. It has increased its presence worldwide, becoming a public health concern due to its innate resistance to antifungals and outbreak potential.Methods: We performed a query using the word "Candida auris" from the Scopus database, further performing a bibliometric analysis with the open-source R package Bibliometrix.
    Results: 907 original articles were retrieved, allowing us to map the principal authors, papers, journals, and countries involved in this yeast research, as well as analyze current and future trends and the number of published articles.
    Conclusion: C. auris will continue to be a pivotal point in fungal resistance research, either for a better understanding of its resistance and pathogenic mechanisms or for developing novel drugs.
    DOI:  https://doi.org/10.1155/2023/2385018
  44. Gen Dent. 2023 Nov-Dec;71(6):71(6): 32-40
      Mouthguards (MGs) are essential devices for the protection of sports-related orofacial injuries. Mapping of the literature on this subject may help to guide future studies; therefore, this review aimed to characterize the research trends of studies related to MGs and dental injuries in sports activities through bibliometric analysis of in vivo studies concerning the frequency of MG use; knowledge, awareness, perception, and/or attitude about MGs; and adaptation (fit) of MGs in the mouth and/or prevention of traumatic dental injuries (TDIs). A literature search was performed in 6 databases for studies published up to April 2022. Text mining and analysis software was used to extract and evaluate data related to the study author, country, keywords, journal of publication, and year. Additionally, data related to the type of study, outcome, study population, age group, evaluation method, type of MG, sport classification, and sport category were extracted and analyzed. Of 6140 records identified, 222 were included in the analysis. Most of the articles came from the United States (n = 39; 17.5%) and dentistry journals (n = 145; 65.3%). The journal Dental Traumatology (n = 60; 27.0%) presented the highest number of publications. Most studies were observational (n = 195; 87.8%) and evaluated the frequency of MG use (n = 163; 44.4%). Studies were carried out in athletes (n = 181; 82.6%) and adults (n = 169; 49.1%) using questionnaires or interviews for assessment (n = 206; 84.1%). Only 89 (40.1%) studies evaluated the type of MG, mostly involving contact sports. Custom-made MGs were most commonly studied. More studies involving coaches, dentists, and child and teenaged athletes are warranted to help prevent sportsrelated TDIs in young teeth, mainly through interventional studies on the perceptions of and knowledge about MGs among these populations.
    Keywords:  athletic injuries; dental injuries; mouth protectors; personal protective equipment; sports equipment
  45. Heliyon. 2023 Oct;9(10): e21016
      This article aims to undertake a bibliometric review along with a conceptual and intellectual analysis of research on distance learning and e-learning. The purpose of this study is to focus on several academic fields and offer a comprehensive approach on how research on distance learning and e-learning has been approached since 1970. This work applies several bibliometric techniques to assess the research evolution of topics addressed, the most productive authors and the most influential journals. The findings revealed an exponential increase of publications over the last 20 years, highlighting the evolution of topics. The research themes include four main groups: the first relates to pedagogical processes in terms of effectiveness, outcomes, learning strategies, interaction, and self-regulation; the second group includes aspects associated with ICT applied in distance education; the third group focuses on the perceived value, usefulness, acceptance, and satisfaction of e-learning; and the last group portrays the forced application of distance learning strategies to deal with the consequences of the pandemic. This work contributes to expanding the existing literature devoted to study the structure of research on e-learning. It analyses the most representative authors, institutions, and documents, and gathers the growing literature on e-learning, from distance learning in the seventies until the implementation of online learning in the COVID-19 era.
    Keywords:  Distance education and on-line learning; Education; Technology; bibliometrics; e-learning
    DOI:  https://doi.org/10.1016/j.heliyon.2023.e21016
  46. J Robot Surg. 2023 Oct 26.
      Robotic-assisted surgical systems hold promise in enhancing total knee arthroplasty (TKA) outcomes and patients' quality of life. This study aims to comprehensively analyze the literature on robot-assisted total knee arthroplasty (r-TKA), providing insights into its current development, clinical application, and research trends. A systematic search was conducted in the Web of Science Core Collection (WOSCC) to identify relevant articles. Data were collected from the top 100 highly cited articles. Article evidence levels were assessed following established guidelines. Statistical analyses and visualizations were performed to reveal publication trends, citations, research hotspots, and collaborative networks. The analysis covered 100 highly cited articles meeting the research criteria, with a focus on the last five years. The United States emerged as a major contributor, with most publications and citations in the Journal of Knee Surgery and Knee Surgery Sports Traumatology Arthroscopy. Research priorities revolved around clinical outcomes, accuracy, and alignment of r-TKA. Notably, higher evidence levels correlated with more citations, indicating greater attention. Interest in and research on r-TKA is steadily increasing, with a few countries at the forefront of these endeavors. While numerous studies have already reported short- to medium-term follow-up results, it is crucial to conduct longer-term investigations to gain a more comprehensive understanding of the clinical benefits that r-TKA offers compared to conventional techniques. Through ongoing research and a greater embrace of robotic technology, we can continue to improve the quality of life for patients undergoing knee arthroplasty.
    Keywords:  Bibliometric analysis; Knee; Robot-assisted; Robotic technology; Total knee arthroplasty
    DOI:  https://doi.org/10.1007/s11701-023-01742-4
  47. J Neurosurg Spine. 2023 Sep 29. 1-8
      OBJECTIVE: The American Association of Neurological Surgeons (AANS)/Congress of Neurological Surgeons (CNS) Joint Spine Section awards highlight outstanding abstracts submitted to the AANS/CNS Section on Disorders of the Spine and Peripheral Nerves by trainees interested in spine surgery, although the academic trajectory of awardees has not been studied. The aim of this study was to assess the academic career progression of prior recipients of the Journalistic and Academic Neurosurgical Excellence (JANE), Mayfield, and Kuntz research awards.METHODS: Prior JANE, Mayfield, and Kuntz award recipients were identified using awardee records accrued between 1984 and February 2022. Awardee sex, country of residence, specialty, subspecialty focus, and current academic appointment status (if applicable) were searched online. Awardee h-indices and number of peer-reviewed publications were assessed via Google Scholar profiles (or Scopus if unavailable) and PubMed, respectively. Receipt of federal research funding as principal investigator (PI) was determined using the websites of the National Institutes of Health, the National Science Foundation, and the Department of Defense Congressionally Directed Medical Research Programs. The abstract-to-publication rate was assessed.
    RESULTS: A total of 7 JANE awards, 57 Mayfield awards, and 149 Kuntz awards were identified. Of the JANE awardees, all recipients were male. Of the 4 unique JANE awardees who completed training, 2 (50.0%) held academic appointments at the time of the study. All of the JANE abstracts were published in peer-reviewed journals. The mean h-index of all JANE awardees was 28 and the mean number of publications was 126. None of the awardees have received federal research funding. Of the Mayfield awards, 98.2% were awarded to males. Of the 43 unique Mayfield awardees who completed training, 20 (46.5%) held faculty appointments at academic medical centers. All of the Mayfield abstracts since 2011 were published in peer-reviewed journals. The mean h-index of all Mayfield awardees was 26 and the mean number of publications was 82. Five Mayfield awardees received National Institutes of Health funding as PI, and 7 awardees received Department of Defense funding as PI. Of the Kuntz awards, 95.3% were awarded to males. Most awards were given to current residents and fellows (46.3%). Of the 55 unique Kuntz awardees who completed training, 31 (56.4%) held faculty appointments at academic medical centers. The abstract-to-publication rate of the total Kuntz abstracts was 70.5%. The mean h-index of all Kuntz awardees was 15 and the mean number of publications was 58. Five Kuntz awardees (3.4%) received federal research funding as PI.
    CONCLUSIONS: Many recipients of the JANE, Mayfield, and Kuntz Joint Spine Section awards have successfully translated award abstracts into peer-reviewed publications. Furthermore, approximately one-third of the awardees are active in academic neurosurgery, with some having secured federal research funding.
    Keywords:  JANE; Journalistic and Academic Neurosurgical Excellence; Kuntz; Mayfield; Spine Section
    DOI:  https://doi.org/10.3171/2023.7.SPINE23259
  48. Biomed Rep. 2023 Nov;19(5): 81
      For patients diagnosed with advanced malignant parotid tumour, radical parotidectomy with facial nerve sacrifice is part of the treatment. Multiple surgical techniques have been developed to cure facial paralysis in order to restore the function and aesthetics of the face. Despite the large number of publications over time on facial nerve reanimation, a consensus on the timing of the procedure or the donor graft selection has remained to be established. Therefore, the aim of the present study was to conduct a bibliometric analysis to identify and analyse scientific publications on the reconstruction of the facial nerve of patients who underwent radical parotidectomy with facial nerve sacrifice. The analysis on the topic was conducted using the built-in tool of the Scopus database and VOSviewer software. The first 100 most cited articles were separately reviewed to address the aim of the study. No consensus was found regarding the recommended surgical techniques for facial nerve reanimation. The most used donor cranial nerves for transfer included the following: Masseteric branch of the V nerve, contralateral VII nerve with cross-face graft, the XI nerve and the XII nerve. The best timing of surgery is also controversial depending on pre-exiting pathology and degree of nerve degeneration. However, most of the clinical experience suggests facial nerve restoration immediately after the ablative procedure to reduce complications and improve patients' quality of life.
    Keywords:  bibliometric analysis; facial nerve sacrifice; facial reanimation; parotid malignancy
    DOI:  https://doi.org/10.3892/br.2023.1663
  49. Hum Vaccin Immunother. 2023 Dec 15. 19(3): 2270194
      The Coronavirus Disease 2019 (COVID-19) pandemic has now persisted globally for four years, resulting in a staggering death toll of over 4 million individuals. The COVID-19 vaccine has emerged as a highly effective tool in controlling the spread of this virus. However, as the number of individuals receiving COVID-19. In this context, the investigation of adverse reactions related to COVID-19 vaccines holds paramount importance in relevant research. The purpose is to evaluate the current research status regarding adverse reactions associated with COVID-19 vaccines, offering insights for future research. A total of 3,746 articles were included in this analysis, and there has been a notable upward trajectory in the volume of published articles. The CiteSpace v6.1.R6, VOSviewer, SCImago Graphica, and Excel 2019 were employed to analyze and visualize the results. The institutions, countries, journals, authors, co-cited references, and keywords of these articles were analyzed. Furthermore, this study delves into the characteristics of articles on adverse reactions associated with COVID-19 vaccines. It was observed that the number of studies on COVID-19 vaccines has increased year by year since 2019 and witnessed a surge in output in 2021. The vast majority of studies have affirmed the overall safety of COVID-19 vaccines, with adverse reactions tending to be more concentrated in specific diseases. These findings provide valuable ideas for future research in this field and suggest the importance of strengthening international cooperation on adverse reactions to COVID-19 vaccines.
    Keywords:  COVID-19; Citespace; WoSCC; bibliometrics; vaccine
    DOI:  https://doi.org/10.1080/21645515.2023.2270194
  50. Sci Rep. 2023 Oct 24. 13(1): 18166
      Structural topology optimization has gained widespread attention due to more possibilities of innovative structural design. The current research focus/hotspots, application areas, main research scholars, institutions and the countries involved in structural topology optimization are visually presented through clustering and visual analysis based on CiteSpace. The four metric dimensions of the literatures in this paper are as follows: annual quantity of papers and core countries, core authors and co-authors' institutions, hotspots and burst terms, and the highly co-cited papers. The results show the research hotspots in this field are concentrated on keywords such as "level set method", "sensitivity analysis", "homogenization", "genetic algorithm", etc. Regarding the research frontier, "moving morphable component (MMC)", "additive manufacturing (AM)" and "deep learning" are hot topics. In addition, Y. Sui, Z. Kang and O. Sigmund, etc. have high publications. M. Bendsøe and O. Sigmund have high citations. Dalian University of Technology, Technical University of Denmark, etc. are prominent institutions. Moreover, China accounts for more than 34% in the terms of original WOS literatures following by the USA and Australia. This paper could identify structural topology optimization development patterns for the scholars concerned with this field, especially novices, to quickly focus and track the research priorities.
    DOI:  https://doi.org/10.1038/s41598-023-45447-y
  51. Curr Probl Cardiol. 2023 Oct 22. pii: S0146-2806(23)00578-9. [Epub ahead of print] 102161
      ABCG1 is an essential protein involved in the efflux of intracellular cholesterol to the extracellular space, thus playing a critical role in reducing cholesterol accumulation in neighboring tissues. Bibliometric analysis pertains to the interdisciplinary field of quantitative examination of diverse documents using mathematical and statistical techniques. It integrates the investigation of structural and temporal patterns in academic publications with an exploration of subject focus and forms of uncertainty. This research paper examines the historical evolution, current areas of interest, and future development trends of ABCG1 through bibliometric analysis. This study aims to offer readers insights into the research status and emerging trends of ABCG1, thereby assisting researchers in the exciting field to explore novel research avenues. Following rigorous selection, research on ABCG1 has remained highly active over the past two decades. ABCG1 has even started to emerge in previously unrelated fields, such as the field of cancer research. According to the analysis conducted by Citespace, a lot of keywords and influential citations were identified. ABCG1 has been found to establish a connection between cancer and cardiovascular disease, highlighting their interrelationship. This review aims to assist readers who have limited familiarity with ABCG1 research in gaining a rapid understanding of its developmental trajectory. Additionally, it aims to offer researchers potential areas of focus for future studies related to ABCG1.
    Keywords:  ABCG1; Atherosclerosis; Cardiovascular disease; Proliferation
    DOI:  https://doi.org/10.1016/j.cpcardiol.2023.102161
  52. Chemosphere. 2023 Oct 20. pii: S0045-6535(23)02736-4. [Epub ahead of print]345 140466
      This work describes the scientific and academic contributions of Professor Enric Brillas through the analysis of Social Network Analysis and data science. The study examines the research collaborations and co-authorship networks of Professor Brillas, indicating his active engagement and up-to-date collaborations with key co-authors, including Ignasi Sirés and Pere.L. Cabot. The analysis also reveals Professor Brillas' significant research focus on water treatment and related concepts such as oxidation-reduction, Fenton reactions, photoelectro-Fenton, and electrocatalysis. Furthermore, the most cited and recent articles by Professor Brillas are identified and discusses. Overall, the research demonstrates Professor Brillas' notable contributions to the field of electrochemical water treatment and highlights his ongoing research and collaborations in this area.
    Keywords:  Data science; Electro-Fenton; Profesor Brillas; Social network analysis; Water treatment
    DOI:  https://doi.org/10.1016/j.chemosphere.2023.140466
  53. Environ Monit Assess. 2023 Oct 25. 195(11): 1369
      Microplastics, capable of absorbing persistent organic compounds, heavy metals, and emerging pollutants, are of global concern due to their potential to alter the behavior and metabolism of biota. In Latin America, the Pacific Alliance, comprising Mexico, Colombia, Peru, and Chile, stands out for its biological wealth and productive ecosystems, which account for 37% of the region's gross domestic product. The leaders of these countries expressed their concern about microplastic pollution and pledged to take joint action. We conducted an analysis of the scientific production of these countries and the collaborations of their researchers, focused on the period 2015-2023, using Scopus and SCImago. We observed that marine-coastal/wetland ecosystems are the most studied, with a focus on fish, and that Mexico leads in publications, followed by Colombia, Peru, and Chile. In addition, we note the absence of an inter-institutional group dedicated to microplastics research in these countries. We recommend promoting collaboration between academic institutions specialized in microplastic research and government agencies dedicated to the promotion of science and technology in the countries belonging to the Pacific Alliance.
    Keywords:  Pacific Alliance; Publication analysis; SCImago; Scientometry; Scopus; h-index
    DOI:  https://doi.org/10.1007/s10661-023-11990-4
  54. Behav Sci (Basel). 2023 Sep 22. pii: 787. [Epub ahead of print]13(10):
      This study identifies the topical areas of research that have attempted a psychological approach to soccer research over the last 33 years (1990-2022) and explored the growth and stagnation of the topic as well as research contributions to soccer development. Data were obtained from 1863 papers from the Web of Science database. The data were collected through keyword text mining and data preprocessing to determine the keywords needed for analysis. Based on the keywords, latent Dirichlet allocation-based topic modeling analysis was performed to analyze the topic distribution of papers and explore research trends by topic area. The topic modeling process included four topic area and fifty topics. The "Coaching Essentials in Football" topic area had the highest frequency, but it was not statistically identified as a trend. However, coaching, including training, is expected to continue to be an important research topic, as it is a key requirement for success in the highly competitive elite football world. Interest in the research field of "Psychological Skills for Performance Development" has waned in recent years. This may be due to the predominance of other subject areas rather than a lack of interest. Various high-tech interventions and problem-solving attempts are being made in this field, providing opportunities for qualitative and quantitative expansion. "Motivation, cognition, and emotion" is a largely underrated subject area in soccer psychology. This could be because survey-based psychological evaluation attempts have decreased as the importance of rapid field application has been emphasized in recent soccer-related studies. However, measuring psychological factors contributes to the study of football psychology through a new methodology and theoretical background. Recognizing the important role of psychological factors in player performance and mental management, as well as presenting new research directions and approaches that can be directly applied to the field, will advance soccer psychology research.
    Keywords:  bibliometric; data science; psychology; research trends; soccer; topic modeling
    DOI:  https://doi.org/10.3390/bs13100787
  55. Eur J Investig Health Psychol Educ. 2023 Sep 22. 13(10): 2006-2034
      Digital addiction (DA), an umbrella term referring to addiction to any type of digital media, such as the internet, smartphone, digital games, and social media, is a significant factor influencing students' academic achievement (AA). Many scholars have contributed to this line of research from around the world. Nevertheless, the literature lacks a holistic investigation of how the DA-AA research field evolved, which could guide future studies. The current study aims to address this void and conducts a combined bibliometric and science mapping analysis of research addressing the relationship between DA and AA. Data were retrieved from the WoS database, considered one of the optimal databases for such studies with its comprehensive coverage of quality journals. One hundred eighteen articles were included in the final dataset and were analyzed using the SciMAT software, which allowed analysis over three consecutive periods and yielded comparable results regarding the conceptual and thematic evolution of the DA-AA domain. The results indicated an increased research interest in the topic, especially during the last five years. The science mapping analysis showed that the most-studied types of addiction were smartphone addiction for the first two periods and social media addiction for the last. Research in the DA-AA domain which focused on understanding the addictive use of smartphones during the first period, evolved to address factors such as self-efficacy or life satisfaction leading to smartphone addiction and lower grades. During the third period, the number of factors addressed gained significant variety and covered family-related and personal factors.
    Keywords:  academic achievement; academic performance; internet addiction; science mapping; smartphone addiction; social media addiction; technology addiction
    DOI:  https://doi.org/10.3390/ejihpe13100143
  56. Account Res. 2023 Oct 25.
      PURPOSE: This study aims to systematically analyze the acknowledgment of generative AI tools, particularly ChatGPT, in academic publications. It delves into patterns across multiple dimensions, including geographical distribution, disciplinary affiliations, journals, and institutional representation.METHODOLOGY: Using a dataset from the Dimensions database consisting of 1,226 publications from November 2022 to July 2023, the study employs a variety of analytical techniques, including temporal analysis and distribution mapping across fields of research and geographical locations.
    FINDINGS: Acknowledgments are most frequent from authors affiliated with U.S. institutions, followed by significant contributions from China and India. Fields such as Biomedical and Clinical Sciences are highly represented, along with Information and Computing Sciences. Prominent journals like "The Lancet Digital Health" and preprint platforms including "bioRxiv" frequently feature acknowledgments, suggesting an accelerating role for AI tools in expediting research publication.
    LIMITATIONS: The scope of this study is restricted to the Dimensions database, possibly missing data from other platforms or non-indexed literature. Moreover, the study does not evaluate the quality or ethics of the acknowledgments.
    PRACTICAL IMPLICATIONS: The results are instructive for a range of stakeholders, including researchers, academic publishers, and institutions. They offer a foundational understanding that can inform future policies and research on the ethical and transparent use of AI in academia.
    ORIGINALITY: This research is the first empirical investigation of its kind to systematically examine acknowledgment patterns concerning generative AI tools, thus filling an identified gap in existing scholarship.
    Keywords:  ChatGPT; ethics in publishing; fields of research; generative AI; research integrity; science policy; social science research ethics
    DOI:  https://doi.org/10.1080/08989621.2023.2273377
  57. Mar Pollut Bull. 2023 Oct 23. pii: S0025-326X(23)01088-3. [Epub ahead of print]196 115653
      Chromophoric dissolved organic matter (CDOM) occupies a critical part in biogeochemistry and energy flux of aquatic ecosystems. CDOM research spans in many fields, including chemistry, marine environment, biomass cycling, physics, hydrology, and climate change. In recent years, a series of remarkable research milestone have been achieved. On the basis of reviewing the research process of CDOM, combined with a bibliometric analysis, this study aims to provide a comprehensive review of the development and applications of remote sensing in monitoring CDOM from 2003 to 2022. The findings show that remote sensing data plays an important role in CDOM research as proven with the increasing number of publications since 2003, particularly in China and the United States. Primary research areas have gradually changed from studying absorption and fluorescence properties to optimization of remote sensing inversion models in recent years. Since the composition of oceanic and freshwater bodies differs significantly, it is important to choose the appropriate inversion method for different types of water body. At present, the monitoring of CDOM mainly relies on a single sensor, but the fusion of images from different sensors can be considered a major research direction due to the complex characteristics of CDOM. Therefore, in the future, the characteristics of CDOM will be studied in depth inn combination with multi-source data and other application models, where inversion algorithms will be optimized, inversion algorithms with low dependence on measured data will be developed, and a transportable inversion model will be built to break the regional limitations of the model and to promote the development of CDOM research in a deeper and more comprehensive direction.
    Keywords:  Bibliometric; CDOM; Remote sensing; Research hotspots; Trend of development
    DOI:  https://doi.org/10.1016/j.marpolbul.2023.115653
  58. Am J Audiol. 2023 Oct 27. 1-18
      PURPOSE: The purpose of this study was to systematically review the research literature with regards to treatments and intervention methods for hereditary hearing loss. Our goal was to provide reference guidelines for the rational use of medication and gene-targeted therapy for patients with hereditary hearing loss and discuss the future development of research in this area.METHOD: We searched two core databases, PubMed and Web of Science, for relevant literature relating to potential treatments and interventional methods for hereditary hearing loss. Then, we used Microsoft Excel to perform basic statistical analysis of the data, the R language to perform bibliometric analyses, and VOSviewer and CiteSpace to visualize data. In addition, we clustered and descriptively analyzed the data and identified the relative importance of each approach with regard to precise patient outcomes.
    RESULTS: In this study, we followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) standardized screening process and identified a total of 103 research articles. The average annual growth rate of publications in this area was 12.73%. The country with the highest number of publications and citations was the United States; 80 of these publications (associated with 76.92% of funding) were supported by grants from 16 countries. Potential treatments and interventions were clustered according to the stage of research and showed that 8.74% remain in the research design stage, 59.22% are in the clinical validation stage, and 32.04% are being applied in the clinic. The main research focus in this field is cochlear implants and gene therapy.
    CONCLUSIONS: Hereditary hearing loss is in a critical period of transition from preventive to therapeutic research. Gene-targeted interventions represent one of the most promising and effective treatments.
    SUPPLEMENTAL MATERIAL: https://doi.org/10.23641/asha.24309193.
    DOI:  https://doi.org/10.1044/2023_AJA-23-00069
  59. Mar Environ Res. 2023 Oct 18. pii: S0141-1136(23)00344-6. [Epub ahead of print] 106216
      Seaweed has garnered increasing interest due to its capacity to mitigate climate change by curbing carbon emissions from agriculture, as well as its potential to serve as a supplement or alternative for dietary, livestock feed, or fuel source production. Moreover, seaweed is regarded as one of the earliest plant forms to have evolved on Earth. Owing to the extensive body of literature available and the uncertainty surrounding the future trajectory of seaweed research under evolving climate conditions, this review scrutinizes the structure, dynamics, and progression of the literature pertaining to seaweed and climate change. This analysis is grounded in the Web of Science Core Collection database, augmented by CiteSpace software. Furthermore, we discuss the productivity and influence of individual researchers, research organizations, countries, and scientific journals. To date, there have been 8047 articles published globally (after a series of filters and exclusions), with a notable upswing in publication frequency since 2018. The USA, China, and Australia are among the leading countries contributing to this research area. Our findings reveal that current research on seaweed and climate change encompasses 13 distinct research clusters, including "marine heatwave", "temperate estuary", "ocean acidification", and "macroalgal bloom". The most frequently cited keywords are "climate change", "biomass", "community", and "photosynthesis". The seaweed species most commonly referenced in relation to climate change include Gracilaria sp., Sargassum sp., Ecklonia maxima, and Macrocystis pyrifera. These results provide valuable guidance for shaping the direction of specialized topics concerning marine biodiversity under shifting climate conditions. We propose that seaweed production may be compromised during prolonged episodes of reduced water availability, emphasizing the need to formulate strategies to guarantee its continued viability. This article offers fresh perspectives on the analysis of seaweed research in the context of impending climate change.
    Keywords:  Ecklonia maxima; Eutrophication; Macrocystis pyrifera; Photosynthesis; Phytoplankton; Rhodophyta
    DOI:  https://doi.org/10.1016/j.marenvres.2023.106216
  60. IEEE Trans Vis Comput Graph. 2023 Oct 25. PP
      Science has long been viewed as a key driver of economic growth and rising standards of living. Knowledge about how scientific advances support marketplace inventions is therefore essential for understanding the role of science in propelling real-world applications and technological progress. The increasing availability of large-scale datasets tracing scientific publications and patented inventions and the complex interactions among them offers us new opportunities to explore the evolving dual frontiers of science and technology at an unprecedented level of scale and detail. However, we lack suitable visual analytics approaches to analyze such complex interactions effectively. Here we introduce InnovationInsights, an interactive visual analysis system for researchers, research institutions, and policymakers to explore the complex linkages between science and technology, and to identify critical innovations, inventors, and potential partners. The system first identifies important associations between scientific papers and patented inventions through a set of statistical measures introduced by our experts from the field of the Science of Science. A series of visualization views are then used to present these associations in the data context. In particular, we introduce the Interplay Graph to visualize patterns and insights derived from the data, helping users effectively navigate citation relationships between papers and patents. This visualization thereby helps them identify the origins of technical inventions and the impact of scientific research. We evaluate the system through two case studies with experts followed by expert interviews. We further engage a premier research institution to test-run the system, helping its institution leaders to extract new insights for innovation. Through both the case studies and the engagement project, we find that our system not only meets our original goals of design, allowing users to better identify the sources of technical inventions and to understand the broad impact of scientific research; it also goes beyond these purposes to enable an array of new applications for researchers and research institutions, ranging from identifying untapped innovation potential within an institution to forging new collaboration opportunities between science and industry.
    DOI:  https://doi.org/10.1109/TVCG.2023.3327387
  61. Sci Data. 2023 Oct 25. 10(1): 737
      The data paper is becoming a popular way for researchers to publish their research data. The growing numbers of data papers and journals hosting them have made them an important data source for understanding how research data is published and reused. One barrier to this research agenda is a lack of knowledge as to how data journals and their publications are indexed in the scholarly databases used for quantitative analysis. To address this gap, this study examines how a list of 18 exclusively data journals (i.e., journals that primarily accept data papers) are indexed in four popular scholarly databases: the Web of Science, Scopus, Dimensions, and OpenAlex. We investigate how comprehensively these databases cover the selected data journals and, in particular, how they present the document type information of data papers. We find that the coverage of data papers, as well as their document type information, is highly inconsistent across databases, which creates major challenges for future efforts to study them quantitatively, which should be addressed in the future.
    DOI:  https://doi.org/10.1038/s41597-023-02625-x
  62. Arthroscopy. 2023 Oct 23. pii: S0749-8063(23)00859-9. [Epub ahead of print]
      PURPOSE: To describe the prevalence of randomized controlled trials (RCTs) in orthopaedic sports medicine related journals reporting on the social determinants of health (SDOH) of their patient cohorts, including factors receiving less attention, such as education level, employment status, insurance status, and socioeconomic status.METHODS: The PubMed/MEDLINE database was utilized to search for RCTs between 2020 and 2022 from 3 high-impact orthopaedic sports medicine related journals: American Journal of Sports Medicine, Arthroscopy, and Journal of Shoulder and Elbow Surgery. The following information was extracted from each article: age, sex/gender, body mass index (BMI), year published, corresponding author country, and self-reported SDOH factors [race, ethnicity, education level, employment status, insurance status, and socioeconomic status.] RESULTS: A total of 189 articles were analyzed. Articles originated from 34 different countries, with the United States of America (n = 66) producing the greatest number of articles. Overall, age (n = 186; 98.4%) and sex/gender (n = 184; 97.4%) were the factors most commonly reported, followed by BMI (n = 112; 59.3%), race (n = 17; 9.0%), ethnicity (n = 10; 5.3%), employment status (n = 9; 4.8%), insurance status (n = 7; 3.7%), and education level (n = 5; 2.6%). Socioeconomic status was not reported in any of the articles analyzed. Articles from the United States of America report on SDOH factors more frequently than international articles, most notably race (24.2% vs. 0.8%, respectively) and ethnicity (15.2% and 0%, respectively).
    CONCLUSION: RCTs from 3 high-impact orthopaedic sports medicine journals infrequently report on SDOH.
    Keywords:  RCT; SDOH; social determinants of health; sports medicine
    DOI:  https://doi.org/10.1016/j.arthro.2023.10.015
  63. Med Princ Pract. 2023 Oct 25.
      OBJECTIVE: This study aimed to provide a comprehensive overview of the current state of the literature on the therapeutical application of bacteriophages.METHODS: First, a bibliometric analysis was performed using the database Web of Science to determine annual number of publications and citations. Second, a systematic literature review was conducted on randomized-controlled trials (RCTs) of phage therapy in PubMed.
    RESULTS: Over the past decade the number of publications on bacteriophage therapy increased more than fourfold with 212 articles in 2011 and 739 in 2022. The systematic search in PubMed yielded 7 RCTs eligible for inclusion reporting on a total of 418 participants. Identified indications in this study included bacterial diarrhea, urinary tract infections, infected burn wounds, chronic otitis, chronic venous leg ulcers, and chronic rhinosinusitis. In three studies, mild to moderate adverse events were reported in 10/195 participants (5.1%). Three of the studies reported a statistically significant difference in outcomes comparing phage therapy with standard of care or placebo.
    CONCLUSION: Phage therapy has gained increasing interest over the years. RCTs on different indications suggest the safety of phage therapy, however reasons why phage therapy is not yet well accepted are limitations in the study designs. For a successful translation into clinical practice researchers and clinicians should learn from the earlier experiences and consider issues such as the quality of phage preparation, sensitivity testing, titer and dosages, as well as access to the infection site and stability for standardized protocols and future trials.
    DOI:  https://doi.org/10.1159/000534717
  64. Analyst. 2023 Oct 24.
      Metal ions are indispensable elements in living organisms and are associated with regulating various biological processes. An imbalance in metal ion content can lead to disorders in normal physiological functions of the human body and cause various diseases. Genetically encoded fluorescent protein sensors have the advantages of low biotoxicity, high specificity, and a long imaging time in vivo and have become a powerful tool to visualize or quantify the concentration level of biomolecules in vivo and in vitro, temporal and spatial distribution, and life activity process. This review analyzes the development status and current research hotspots in the field of genetically encoded fluorescent protein sensors by bibliometric analysis. Based on the results of bibliometric analysis, the research progress of genetically encoded fluorescent protein sensors for metal ion detection is reviewed, and the construction strategies, physicochemical properties, and applications of such sensors in biological imaging are summarized.
    DOI:  https://doi.org/10.1039/d3an01412f
  65. Pediatr Res. 2023 Oct 25.
      This review utilizes quatitative methods and bibliometric data to analyse the trends of emerging and re-emerging vector-borne diseases, with a focus on their impact on pediatric population. To conduct this analysis, a systematic search of PubMed articles from the past two decades was performed, specifically looking at 26 different vector-borne viruses listed in WHO and CDC list of vector-borne viruses. The review found that diseases like Dengue, Zika, West Nile, and Chikungunya were frequently discussed in the literature. On the other hand, diseases such as Tick-borne encephalitis, Rift Valley fever, Venezuelan equine encephalitis, Sindbis fever, Venezuelan equine encephalitis, Ross River virus, and Eastern equine encephalitis showed an upward trend in publications, indicating potential resurgence. In addition to discussing trends and patterns, the review delves into the clinical manifestations and long-term effects of the top 10 viruses in children. It highlights various factors including deforestation, urbanization, global travel, and immunosuppression that contribute to disease emergence and resurgence. To effectively combat these vector-borne diseases, continuous surveillance is crucial. The review also emphasizes the importance of increased vaccination efforts and targeted research to address the health challenges they pose. IMPACT: This review employs quantitative analysis of publications to elucidate trends in emerging pediatric vector-borne viral diseases over two decades. Dengue, the most prevalent of these diseases, has spread to new regions. New strains of Japanese Encephalitis have caused outbreaks. Resurgence of Tick-borne Encephalitis, West Nile, and Yellow Fever due to vaccine hesitancy has also transpired. Continuous global surveillance, increased vaccination, and research into novel therapeutics are imperative to combat the substantial morbidity and mortality burden these diseases pose for children worldwide.
    DOI:  https://doi.org/10.1038/s41390-023-02866-x
  66. Curr Probl Diagn Radiol. 2023 Oct 20. pii: S0363-0188(23)00166-4. [Epub ahead of print]
      OBJECTIVE: To perform a detailed qualitative and quantitative analysis of the published literature on ChatGPT and radiology in the nine months since its public release, detailing the scope of the work in the short timeframe.METHODS: A systematic literature search was carried out of the MEDLINE, EMBASE databases through August 15, 2023 for articles that were focused on ChatGPT and imaging/radiology. Articles were classified into original research and reviews/perspectives. Quantitative analysis was carried out by two experienced radiologists using objective scoring systems for evaluating original and non-original research.
    RESULTS: 51 articles were published involving ChatGPT and radiology/imaging dating from 26 Jan 2023 to the last article published on 14 Aug 2023. 23 articles were original research while the rest included reviews/perspectives or brief communications. For quantitative analysis scored by two readers, we included 23 original research and 17 non-original research articles (after excluding 11 letters as responses to previous articles). Mean score for original research was 3.20 out of 5 (across five questions), while mean score for non-original research was 1.17 out of 2 (across six questions). Mean score grading performance of ChatGPT in original research was 3.20 out of five (across two questions).
    DISCUSSION: While it is early days for ChatGPT and its impact in radiology, there has already been a plethora of articles talking about the multifaceted nature of the tool and how it can impact every aspect of radiology from patient education, pre-authorization, protocol selection, generating differentials, to structuring radiology reports. Most articles show impressive performance of ChatGPT which can only improve with more research and improvements in the tool itself. There have also been several articles which have highlighted the limitations of ChatGPT in its current iteration, which will allow radiologists and researchers to improve these areas.
    DOI:  https://doi.org/10.1067/j.cpradiol.2023.10.013
  67. Br J Sociol. 2023 Oct 21.
      This study focuses on the predictors of women academics' perceived research productivity during the pandemic in Türkiye, by taking the changes in paid and unpaid workload alongside the felt pressure concerning productivity into consideration. Predicting the odds to report an above the mean level of decrease in perceived research productivity, unlike expected, increased housework time and administrative workload presented no statistically significant effect. On the other hand, extended care responsibilities (including but not limited to childcare) and felt pressure concerning research performance during the pandemic strongly predicted a high level of reported decrease in research productivity. Findings highlight that institutional care support mechanisms should be among the primary concerns since the pandemic has made the already existing gender inequalities in academia more visible in terms of the challenges women face in balancing paid and unpaid work. In addition, as excess pressure felt by women academics regarding research performance is linked to a decline in reported productivity, creating a compassionate environment in academia not only in unprecedented circumstances but at all times needs to be priority.
    Keywords:  academia; gender; higher education; reported research productivity; unpaid care work
    DOI:  https://doi.org/10.1111/1468-4446.13058
  68. PLoS One. 2023 ;18(10): e0291372
      Scientific grant applications are subjected to scholarly peer review. Studies show that the success rates of grant applications are often higher for male than for female applicants, suggesting that gender bias is common in peer review. However, these findings mostly come from studies in Europe, North America and Australia. Here we report the analyses of gender-specific success rates of applications to the fellowships offered by Japan Society for the Promotion of Science (JSPS). Because we analyze the observational data (i.e., not experimental), our aim here is to describe the possible gender gaps in the success rates, rather than the examination of gender bias per se. Results show that the success rates are consistently higher for male applicants than for female applicants among five different fellowship categories. The gender gaps in the success rates varied significantly between research fields in some Fellowship categories. Furthermore, in some fellowship categories, the gender gaps were significantly associated with the representation of female applicants (both positive and negative correlations were found). Though the causes of the gender gaps are unknown, unintentional gender bias during the review process is suggested. Pre-application gender gaps may also be contributing to the gender gaps in success rates. At least some of the observed gender gaps were relatively small, which may be partly explicable by the designs of the review process. However, gender gaps or biases acting prior to the application, such as self-selection bias, may have reduced the superficial gender gaps in the success rates. Further investigations that control for the effects of covariates (e.g., scientific merits of each applicant, which were not accessible to us) and those of other funding agencies, especially of non-Western countries, are warranted.
    DOI:  https://doi.org/10.1371/journal.pone.0291372