bims-evares Biomed News
on Evaluation of research
Issue of 2024–01–07
fifty-five papers selected by
Thomas Krichel, Open Library Society



  1. Drug Deliv Transl Res. 2023 Dec 31.
      Cancer nanomedicine has been an emerging field for drug development against malignant tumors during the past three decades. A bibliometric analysis was performed to characterize the current international trends and present visual representations of the evolution and emerging trends in the research and development of nanocarriers for cancer treatment. This study employed bibliometric analysis and visualization techniques to analyze the literature on antitumor nanocarriers published between 2013 and 2023. A total of 98,980 articles on antitumor nanocarriers were retrieved from the Web of Science Core Collection (WoSCC) database and analyzed using the Citespace software for specific characteristics such as publication year, countries/regions, organizations, keywords, and references. Network visualization was constructed by VOSviewer and Citespace. From 2013 to 2023, the annual global publications increased 7.39 times, from 1851 to 13,683. People's Republic of China (2588 publications) was the most productive country. Chinese Academy of Sciences (298 publications) was the most productive organization. The top 5 high-frequency keywords were "nanoparticles," "drug delivery," "nanomedicine," "cancer," and "nanocarriers." The keywords with the strongest citation bursts recently were "cancer immunotherapy," "microenvironment," "antitumor immunity," etc., which indicated the emerging frontiers of antitumor nanomedicine. The co-occurrence cluster analysis of the keywords formed 6 clusters, and most of the top 10 publications by citation counts focused on cluster #1 (nanocarriers) and cluster #2 (cancer immunotherapy). We further provided insightful discussions into the identified subtopics to help researchers gain more details of current trends and hotspots in this field. The present study processes a macro-level literature analysis of antitumor nanocarriers and provides new perspectives and research directions for future development in cancer nanomedicine.
    Keywords:  Bibliometrics; Cancer nanomedicine; Citespace; Nanocarrier; Visual analysis
    DOI:  https://doi.org/10.1007/s13346-023-01485-7
  2. Asian J Neurosurg. 2023 Dec;18(4): 708-723
      Aim  The aim of this study was to perform a bibliometric analysis of the articles published on posterior instrumentation of cervical spine and to study the general publishing trends over the years in this topic in terms of journals, authors, topics, keywords, collaborating countries, etc. Material and Methods  Articles were searched on the web of science using appropriate keywords. A bibliometric analysis was performed using Bibliometrix R package Results  A total of 1,953 studies were identified between 1991 and 2023 including 1,782 articles and 171 reviews from 198 sources. A total of 3,421 author's keywords were used by 6,725 authors. Thirty-four documents are single authored. The average co-author per document is 5.63. The average citation per document is 22.62. There is international co-authorship in 13.11% documents. RM Xu and Sonntag VKH have maximum publications ( n  = 28). The "Spine" journal has the maximum number of publications ( n  = 335) and best H index of 64. United States has maximum number of publications ( n  = 1,720) and citations ( n  = 19,573). Publication by Harms et al in the "Spine" in 2001 has the highest global ( n  = 956) & local ( n  = 272) citations. Three-dimensional printing and atlantoaxial fixation are emerging trends. Conclusion  The findings of this study enhance the knowledge on the topic of posterior instrumentation of cervical spine and shall guide the trends and directions of future research and innovation.
    Keywords:  bibliometric analysis; cervical spine; lateral mass fixation; pedicle screw fixation; posterior instrumentation
    DOI:  https://doi.org/10.1055/s-0043-1777274
  3. Bladder (San Franc). 2023 ;10 e21200014
       Background: Urinary incontinence (UI) is highly prevalent and poses a considerable social and economic burden on both victims and the society at large. This study reviewed the UI-related literature to present the current status and predict future trends of UI researh.
    Methods: Studies related to UI published between 2012 and 2022 were retrieved from the Web of Science Core Collection. The bibliometric analysis and visualized study were performed by using VOSviewer.
    Results: A total of 3092 publications were retrieved for further analysis. The United States ranked the first in terms of the total number of publications, citations, the H-index of publications. The institutions with the most cited publications was the N8 Research Partnership. Neurourology and Urodynamics published most papers, was cited most frequently, and scored the highest H-index. The author with the most citations, and the greatest average citations per article was Nitti VW. The author with the highest H-index was Herschorn S. Articles were divided into five main clusters based on keyword analysis: epidemiological studies, diagnosis studies, therapy studies, female urinary incontinence studies, and male urinary incontinence studies. UI-related epidemiology, therapies and male UI will continue to be the hot topics.
    Conclusions: This study indicated that the UI research is more intensive in Europe and North America, Neurourology and Urodynamics was the most influencial journal in the field. Moreover, epidemiology, therapy and male urinary incontinence will continue to be hot topics. Our study contributes to a more comprehensive understanding of the status quo and provides clues to future research directions of UI.
    Keywords:  Urinary incontinence; bibliometrics; incontinence; neurourology; visualized analysis
    DOI:  https://doi.org/10.14440/bladder.2023.873
  4. J Indian Assoc Pediatr Surg. 2023 Nov-Dec;28(6):28(6): 497-507
       Introduction: A scientometric analysis was conducted to characterize the global research publications in extrahepatic portal venous obstruction (EHPVO), and state-of-the-art visualization graphics were generated to provide insight into specific bibliometric variables.
    Materials and Methods: The Web of Science database was accessed for research productivity and bibliometric variables of countries, institutions, authors, journals, and content analysis of top-20 cited documents were performed. Collaborative networks and co-occurrence of keywords map were generated using VOSviewer software.
    Results: Two hundred and sixteen records were retrieved with an annual growth rate of 2.53%. India is the leading country in productivity (n = 4339), followed by the USA and China. Post Graduate Institute of Medical Education and Research, Chandigarh, was the top productive institute. Sarin SK was the most prolific author, having the highest citations received and h-index. The hotspot topics were "portal hypertension," "cirrhosis," "children," "biliopathy/cholangiopathy," "liver fibrosis," and "liver transplantation" as per keyword co-occurrence networking. J Gastroenterol Hepatol had the most publications of EHPVO research as well the h-index. Regarding collaborative network mapping, the USA and Primignani M were the significant nodes among country and author, respectively.
    Conclusion: EHPVO research publication volume is low but is gradually progressing with dominant contributions from Indian institutes and authors. Most highly cited articles are of low level of evidence, and multi-institutional collaborative research can be the way forward.
    Keywords:  Bibliometric study; VOSviewer; citation analysis; extra-hepatic portal venous obstruction; keyword co-occurrence mapping; scientometrics
    DOI:  https://doi.org/10.4103/jiaps.jiaps_61_23
  5. Front Immunol. 2023 ;14 1323115
       Background: Cancer-associated fibroblasts (CAFs) represent the predominant stromal component within the tumour microenvironment (TME), exhibiting considerable heterogeneity and plasticity that significantly impact immune response and metabolic reprogramming within the TME, thereby influencing tumour progression. Consequently, investigating CAFs is of utmost importance. The objective of this study is to employ bibliometric analysis in order to evaluate the current state of research on CAFs and predict future areas of research and emerging trends.
    Methods: Conduct a comprehensive search for scholarly publications within the Web of Science Core Collection database, encompassing the time period from January 1, 2001, to December 31, 2022. Apply VOSviewer, CiteSpace, R software and Microsoft Excel for bibliometric analysis and visualisation.
    Results: This study involved a comprehensive analysis of 5,925 publications authored by 33,628 individuals affiliated with 4,978 institutions across 79 countries/regions. These publications were published in 908 journals, covering 14,495 keywords and 203,947 references. Notably, there was a significant increase in articles published between 2019 and 2022. China had the highest count of articles, while the United States emerged as the most frequently cited country. The primary research institutions in this field were Shanghai Jiao Tong University, Harvard University, and the University of Texas MD Anderson Cancer Center. Sotgia, Federica and Lisanti, Michael P from the University of Manchester, and Martinet, Wim from the University of Antwerp were the most prolific and highly cited authors. The journal Cancers had the highest number of publications, while Cancer Research was the most frequently cited journal. Molecular, biology, immunology, medicine and genetics were the main research disciplines in the field of CAFs. Key directions in CAFs research encompassed the study of transforming growth factor-β, Fibroblast Activation Protein, breast cancer, as well as growth and metastasis. The findings from the analysis of keyword co-occurrence and literature co-citation have revealed several emerging hotspots and trends within the field of CAFs. These include STAT3, multidrug resistance, pancreatic ductal adenocarcinoma, pan-cancer analysis, preclinical evaluation, ionizing radiation, and gold nanoparticles.
    Conclusion: Targeting CAFs is anticipated to be a novel and effective strategy for cancer treatment. This study provides a comprehensive overview of the existing research on CAFs from 2001 to 2022, utilizing bibliometric analysis. The study identified the prominent areas of investigation and anticipated future research directions, with the aim of providing valuable insights and recommendations for future studies in the field of CAFs.
    Keywords:  bibliometrics; cancer; cancer-associated fibroblasts; hot spots; research trends
    DOI:  https://doi.org/10.3389/fimmu.2023.1323115
  6. Front Pain Res (Lausanne). 2023 ;4 1233444
       Introduction: Neuropathic Pain (NP) is often accompanied by mood disorders, which seriously affect the quality of life of patients. This study aimed to analyze the hotspots and trends in NP-related mood disorder research using bibliometric methods and to provide valuable predictions for future research in this field.
    Methods: Articles and review articles on NP-related mood disorders published from January 2003 to May 2023 were retrieved from the Web of Science Core Collection. We used CiteSpace to analyze publications, countries, institutions, authors, cited authors, journals, cited journals, references, cited references, and keywords. We also analyzed collaborative network maps and co-occurrence network maps.
    Results: A total of 4,540 studies were collected for analysis. The number of publications concerning NP-related mood disorders every year shows an upward trend. The United States was a major contributor in this field. The University of Toronto was the most productive core institution. C GHELARDINI was the most prolific author, and RH DWORKIN was the most frequently cited author. PAIN was identified as the journal with the highest productivity and citation rate. The current research hotspots mainly included quality of life, efficacy, double-blind methodology, gabapentin, pregabalin, postherpetic neuralgia, and central sensitization. The frontiers in research mainly focused on the mechanisms associated with microglia activation, oxidative stress, neuroinflammation, and NP-related mood disorders.
    Discussion: In conclusion, the present study provided insight into the current state and trends in NP-related mood disorder research over the past 20 years. Consequently, researchers will be able to identify new perspectives on potential collaborators and cooperative institutions, hot topics, and research frontiers in this field.
    Keywords:  CiteSpace; Web of Science; bibliometric analysis; mood disorders; neuropathic pain
    DOI:  https://doi.org/10.3389/fpain.2023.1233444
  7. Front Psychol. 2023 ;14 1327656
       Aim: As drama therapy has become increasingly important in healthcare, the number of scientific publications has increased, complicating the orientation in the research field. Therefore, the aim of this study is to provide a comprehensive overview of research trends in drama therapy, assessing the impact factors of publications and analyzing the research structure.
    Methods: Three hundred and ninety-five scientific articles indexed in Scopus were analyzed without time, geographic and language restrictions using bibliometric analysis methods - performance analysis, citation analysis, and science mapping. Data processing was performed using MS Excel, VOSviewer and Biblioshiny software.
    Results: The work of the pioneers of drama therapy continues to be actively cited, influencing the development of drama therapy. Today's leading researchers are increasingly engaging in collaborative research, working across disciplines and contributing to scientific progress. The hot topic of research is older adults and mental health. The diversity of terminology and the large volume of unpublished research point to the need for consolidation. Altmetric analysis would optimize the use of scientific information, promoting innovative research.
    Conclusion: This is the first study using the Scopus database to perform an extensive bibliometric analysis of research articles on drama therapy applying Biblioshiny and VOSviewer software. The results of the analysis reflect the evolution of the field from its historical roots to academic maturity, highlighting its current dynamic growth and the trend of drama therapy to establish itself as an interdisciplinary field in the healthcare system. This work serves as a valuable resource for the scientific community, professionals, students, and librarians in the field, helping to optimize the use of scientific resources in drama therapy and contributing to its future development.
    Keywords:  Scopus; bibliometric analysis; creative arts therapies; drama therapy; dramatherapy; health care; research trends; scientific publications
    DOI:  https://doi.org/10.3389/fpsyg.2023.1327656
  8. Int J Surg. 2024 Jan 04.
      Various immunotherapy has been greatly applied to comprehensive treatment of malignant cancer under different degrees of tumor burden. Scientific researches have gained considerable progress in the relationship between immunotherapy and tumor burden in recent years. This review aimed to explore the prospect and developing trends in the field of tumor burden and immunotherapy from a bibliometric perspective. Articles about tumor burden and immunotherapy were collected from the Web of Science Core Collection (WoSCC) (retrieved on January 3, 2023). The R package "Bibliometrix" analyzed the primary bibliometric features and created a three-filed plot to display the relationship between institutions, countries and keywords. VOSviewer was used for co-authorship analysis, co-occurrence analysis and their visualization. And CiteSpace calculated the citation burst references and keywords. A total of 1030 publications were retrieved from 35 years of scientific researches. The United States (US) and China published the most articles. The most productive journals were Cancer Immunology Immunotherapy and Journal for ImmunoTherapy of Cancer. The top one institution of the highest output was University of Texas MD Anderson Cancer Center. The hot keywords of strong citation burst strength in recent years were "nivolumab", "tumor microenvironment" and "immune checkpoint inhibitor". The most popular tumor type is melanoma. This bibliometric analysis mapped a basic knowledge structure. The field of tumor burden and immunotherapy is entering a rapid growing stage and keeping it value for future research.
    DOI:  https://doi.org/10.1097/JS9.0000000000001022
  9. Front Pharmacol. 2023 ;14 1326583
      Background: A traumatic spinal cord injury (TSCI) can lead to severe nerve damage and disability. Cell transplantation therapy has shown great potential in the reconstruction of damaged spinal cords and promoting functional recovery. However, there is a lack of frontiers and futures analysis in the study of cell transplantation in TSCI. Methods: We used CiteSpace, VOSviewer and biblilometrix R package to perform bibliometric analysis on cell transplantation in TSCI from 2013 to 2023. Bibliometric records were extracted from English articles and reviews from the Web of Science core collection. Results: The bibliometric analysis included 284 papers published in 154 journals by 1,780 authors from 487 institutions in 41 countries and regions. The number of articles published in the past decade has fluctuated slightly, while the number of article citations has steadily increased. Mainland China and the United States are the leading countries and regions in this field, with the National Natural Science Foundation of China being the most funded foundation, and the United States being the country with the most funded articles. The University of Toronto in Canada is a prolific institution. Michael G. Fehlings has published the most articles, and D Michele Basso is the most cited author. Cell transplantation is the most published journal, and the Journal of Neurotrauma is the most cited journal. Cell and tissue engineering and clinical neurology are the basic disciplines in this field, and cutting-edge disciplines include developmental biology, biochemistry and molecular biology, and materials science and multidisciplinary. This study also helps scholars understand the current hotspots and future trends in this field. Marrow stromal cells, glial progenitor, and cell therapy are current research hotspots in this field, while nerve regeneration, cell therapy, and the safety of transplantation of transplantation may be potential research directions in the future. Conclusion: Cell transplantation after TSCI is receiving increasing attention. Cell therapy is both the frontier and a possible future trend in TSCI research. In addition, glial progenitor and marrow stromal cells are also current research hotspots. Meanwhile, nerve regeneration and safety of transplantation may be potential research directions. These findings will help further deepen research on cell transplantation for TSCI in scientific work.
    Keywords:  bibliometric analysis; cell therapy; cell transplantation; marrow stromal cells; safety; traumatic spinal cord injury
    DOI:  https://doi.org/10.3389/fphar.2023.1326583
  10. Acta Otorhinolaryngol Ital. 2023 Dec 29.
       Objective: This study aimed to investigate the global research status, hot topics, and prospects in the field of sinonasal inverted papilloma (SNIP) through bibliometric analysis.
    Methods: The literature on SNIP was retrieved and downloaded from the Web of Science Core Collection from 2002 to 2021. The bibliometric and visualisation networks of SNIP were constructed using VOSviewer 1.6.18, CiteSpace 6.1. R2, and a bibliometric online analysis platform.
    Results: A total of 560 original articles about SNIP research were included, involving 2,457 authors from 610 institutions in 45 countries. The number of SNIP publications showed an overall rising trend, with an average annual output of 28 articles and almost 3 times as many articles published in 2020 as in 2002. The analysis of keyword burst detection indicated that EGFR mutation, malignant transformation and infection are emerging research hotspots. Moreover, EGFR mutation, KRAS mutation, malignant tumour, metallothionein 2a gene, pre-operative diagnosis, HPV-negative tumour, and expression were among the 11 key clusters of co-cited references.
    Conclusions: This study provided a comprehensive, systematic, and objective analysis and visualised knowledge map of SNIP over the past 2 decades. In particular, current hotspots and prospective trends in the field of SNIP have been identified. These results highlight the future direction of SNIP research for rhinologists.
    Keywords:  bibliometric analysis; hot topics; research status; sinonasal inverted papilloma; web of science core collection database
    DOI:  https://doi.org/10.14639/0392-100X-N2522
  11. Phys Sportsmed. 2024 Jan 04.
       OBJECTIVES: The purpose of this study was to identify the 50 most-cited publications relating to lacrosse since 1990 and conduct a bibliometric analysis of the identified studies.
    METHODS: Clarivate Analytics Web of Science database was queried to identify all publication titles, abstracts, and keywords for the term 'lacrosse' on 9 June 2023. The resulting articles were sorted by total number of citations. Titles and abstracts were included based on their relevance to lacrosse. Once the 50 most cited articles were identified, each article was further analyzed to obtain author name, publication year, country of origin, journal name, article type, research topic, competition level, total number of citations, and the level of evidence. Citation density (total number of citations/years since publication) was calculated and recorded for each of the most-cited studies.
    RESULTS: The 50 most-cited articles were cited 4237 of times with an average of 84 citations per article. The most cited article was cited 637 (15.0%) times. The articles came from 2 different countries, with the United States and Australia comprising 49 and 1 articles, respectively. All articles were published in English. The American Journal of Sports Medicine published the most articles (n = 21, 42.0%). The most studied topic was concussion/traumatic brain injury (n = 18) followed by studies assessing all injuries (n = 7). Collegiate-level lacrosse was the most studied level of competition (n = 22), while high school-level followed (n = 12).
    CONCLUSIONS: The majority of the 50 most-cited articles related to lacrosse since 1990 focus on the prevalence, diagnosis and identification of concussion/traumatic brain injury in high school and collegiate-level athletes. These articles are predominantly epidemiological or cohort studies with Level III or IV evidence that almost unanimously originate from the United States.
    Keywords:  Most cited articles; concussions; lacrosse; sports injuries; traumatic brain injury
    DOI:  https://doi.org/10.1080/00913847.2024.2301919
  12. Ren Fail. 2024 Dec;46(1): 2292142
       INTRODUCTION: The prevalence of chronic kidney disease (CKD) is gradually increasing in the elderly population. At the same time, frailty has become one of the research hotspots in the field of geriatrics. Bibliometric analyses help to understand the direction of a field. Therefore, this study aimed to analyze the status and emerging trends of frailty in CKD patients.
    DATA AND METHODS: The Web of Science Core Collection (WoSCC) database was screened for relevant literature published between 1 January 2000 and 31 December 2021. Next, publications were analyzed for information including authors, journals, cited references, citing journals, institutions, countries and regions, high-frequency keywords and co-citations using VOSviewer, Microsoft Excel, and R software.
    RESULTS: A total of 2223 articles were obtained, from which 613 relevant articles were selected based on title and abstract screening. There was an upward trend in the number of annual publications and Johansen KL was considered the most contributing author in the field. The Clinical Journal of the American Society of Nephrology was the most productive research journal. Johns Hopkins University is the most published organization. The United States is the global leader in the field and contributes the most to research. Research hotspots focus on epidemiological studies of frailty and frailty intervention.
    CONCLUSIONS: This study presents a comprehensive bibliometric analysis of CKD and frailty research. Key findings highlight the current focus on early screening and assessment of frailty in CKD patients, as well as physical function interventions in frail patients.
    Keywords:  Chronic kidney disease (CKD); bibliometrics; frailty; research trends; visualized study
    DOI:  https://doi.org/10.1080/0886022X.2023.2292142
  13. Medicine (Baltimore). 2024 Jan 05. 103(1): e36670
      Lupus nephritis (LN) is a complication of systemic lupus erythematosus and a damaging disease of the kidney. The injury of LN in children is more serious than that in adults. However, the literature in this field is numerous and complex, which brings great challenges for researchers to extract information. The purpose of this study is to carry out bibliometric analysis and visualization of published literatures, and identify current research hotspots and future research trends in this field. Literature was retrieved from the Web Of Science database from 1999 to 2022. The literature was analyzed and visualized using Citespace 6.1.R6, VOSviewer 1.6.18, and Microsoft Excel 2019. A total of 1059 articles were included in this study. In the past 13 years, an increase in the number of publications every year. Brunner HI is the author with the highest number of published and cited papers in this field, followed by Wenderfer SE. The United States and China are the countries with the highest number of published papers. University Toronto is the most productive institution, followed by University Cincinnati. The most prolific journal was Pediatric nephrology (IF 2.67), followed by lupus (IF 2.21). Lupus was cited the most, followed by Pediatric nephrology. The keyword burst showed the earliest and longest burst was antiphospholipid antibody, validation/risk/rituximab/safety is the current research hotspot. The article with the highest number of citations was Hochberg MC 1997 published in Arthritis Rheum. This study provides valuable information summary for the field of LN in children, which is helpful to strengthen the cooperation among countries, institutions and authors, and promote the research in the field of LN in children.
    DOI:  https://doi.org/10.1097/MD.0000000000036670
  14. World J Transplant. 2023 Dec 18. 13(6): 391-402
       BACKGROUND: The United States has witnessed significant advancements in the field of organ transplantation over the course of the last five decades, as demonstrated by a notable increase in the quantity of academic research. The presence of a highly dynamic research environment necessitates continuous evaluations to maintain the integrity and progress of the field.
    AIM: To evaluate the total output and thematic emphasis of transplant research conducted in the United States.
    METHODS: On January 10, 2023, we conducted a bibliometric search of United States research output in transplantation journals from the Web of Science database's Science Citation Index Expanded. We excluded editorials, meeting abstracts, and other non-article types. We analyzed annual trends, authors, institutions, articles, keywords, and countries collaborating with the United States, using VOSviewer 1.6.18 to create figures and tables.
    RESULTS: The United States published 25956 papers (3078 reviews and 22878 articles) representing 37.7% of the world's scientific output. Canada emerged as the top collaborator with the United States, co-authoring 1263 articles. Leading institutions in United States transplantation research were the University of Pittsburgh (1749 articles), Mayo Clinic (1605 articles), Harvard Medical School (1549 articles), and Johns Hopkins University (1280 articles). The top three keywords with over 2000 occurrences were "recipients," "survival," and "outcomes," indicating a focus on graft and recipient outcome markers by United States researchers.
    CONCLUSION: Our findings demonstrate the United States leadership in organ transplantation research, contributing significantly to the global scientific output in this field. However, opportunities exist for fostering expansive partnerships, particularly with developing countries. This study provides valuable insights into the transplantation research landscape in the United States, emphasizing the importance of ongoing evaluations to maintain and propel advancements in this critical medical discipline. The results may facilitate future collaborations, knowledge exchange, and the pursuit of innovative solutions in the realm of organ transplantation.
    Keywords:  Bibliometrics; Organ transplantation; Research output; Scientometrics; United States
    DOI:  https://doi.org/10.5500/wjt.v13.i6.391
  15. Environ Sci Pollut Res Int. 2024 Jan 04.
      The demand for sustainable energy is increasingly urgent to mitigate global warming which has been exacerbated by the extensive use of fossil fuels. Solar energy has attracted global attention as a crucial renewable resource. This study conducted a bibliometric analysis based on publication metrics from the Web of Science database to gain insights into global solar power research. The results indicate a stable global increase in publications on solar power generation and a rise in citations, reflecting growing academic interest. Leading contributors include China, the USA, South Korea, Japan, and India, with the Chinese Academy of Sciences emerging as the most prolific institution. Multidisciplinary Materials Science, Applied Physics, Energy and Fuels, Physical Chemistry, and Nanoscience and Nanotechnology were the most used and promising subject categories. Current hot topics include the systematic analysis of photovoltaic systems, perovskite as a solar cell material, and focusing on stability and flexibility issues arising during photovoltaic-grid integration. This study facilitates a comprehensive understanding of the status and trends in solar power research for researchers, stakeholders, and policy-makers.
    Keywords:  Bibliometric analysis; Hot topics; Science mapping; Scientific production; Solar power generation
    DOI:  https://doi.org/10.1007/s11356-023-31715-x
  16. Clin Exp Rheumatol. 2024 Jan 03.
       OBJECTIVES: Takayasu's arteritis (TAK) is an uncommon granulomatous large-vessel vasculitis associated with significant morbidity and mortality. This study endeavours to comprehend the research status and future frontiers through a bibliometric analysis.
    METHODS: Relevant original articles published in English were acquired from the Science Citation Index Expanded of the Web of Science Core Collection. Analysis of countries/regions, institutions, authors, co-cited references, and keywords were done using Citespace and VOSviewer software.
    RESULTS: The final analysis included 2215 documents contributed by 9091 scholars from 2053 institutions in 83 countries, with the United States being the largest contributor globally. Institutional and author collaboration analysis showed that collaborations are scattered and lack stable and intensive collaborative relationships. The journal 'Clinical and Experimental Rheumatology' was the most prolific journal. Anti-endothelial cell antibodies, interleukin-6, adalimumab, colour Doppler ultrasonography, and stents and prosthesis were the main research areas in TAK.Double-blind multicentre clinical trials, disease activity evaluation and cytokines were identified to be recent keyword bursts.
    CONCLUSIONS: Although the area of TAK research is growing rapidly, intensive institutional and author collaboration has to be fostered in the future to fuel TAK research and information dissemination. Future research on TAK may revolve around cytokines, disease activity evaluation and clinical trials.
    DOI:  https://doi.org/10.55563/clinexprheumatol/akl7x6
  17. Heliyon. 2024 Jan 15. 10(1): e23329
      Worldwide new trends of online cyberbullying are emerging that impact on health and are a factor in adolescent suicide. The objective of this study is to know the development of scientific production and to compare the current trends that encompass the concepts of cyberaggression in young people (CAY) and cybervictimisation in young people (CVY). The methodology used in this study was descriptive with a bibliometric analysis on CAY with 481 documents and CVY with 1087 documents, in addition to a co-word analysis of both terms from the years 2017-2021. These data were extracted from the Web of Science database and network maps were made using VOSviewer software. The results show that the terms CAY and CVY were born in 2006 and have had a different evolutionary progression in the scientific literature until 2021, in addition, the area of psychology stands out with more research on other areas, developed countries are the ones that carry out more studies of CAY and CVY and that the term "suicide" is the most prominent term since 2018 from the CVY. Finally, a discussion and conclusion of the results was made, which can serve as a turning point for future lines of research.
    Keywords:  Adolescents; Bibliometric analysis; Cyberaggression; Cyberbullying; Cybervictimisation; VOSviewer; Web of science
    DOI:  https://doi.org/10.1016/j.heliyon.2023.e23329
  18. Heliyon. 2024 Jan 15. 10(1): e23599
      Sepsis is a systemic syndrome involving physiological, pathological, and biochemical abnormalities precipitated by infection and is a major global public health problem. Endothelial cells (ECs) dysfunction is a major contributor to sepsis-induced multiple organ failure. This bibliometric analysis aimed to identify and characterize the status, evolution of the field, and new research trends of ECs and sepsis over the past 20 years. For this analysis, the Web of Science Core Collection database was searched to identify relevant publications on ECs in sepsis published between January 1, 2002, and December 31, 2022. Microsoft Excel 2021, VOSviewer software, CiteSpace software, and the online analysis platform of literature metrology (http://bibliometric.com) were used to visualize the trends of publications' countries/regions, institutions, authors, journals, and keywords. In total, 4200 articles were identified and screened, primarily originating from 86 countries/regions and 3489 institutions. The USA was the leading contributor to this research field, providing 1501 articles (35.74 %). Harvard University's scientists were the most prolific, with 129 articles. Overall, 21,944 authors were identified, among whom Bae Jong Sup was the most prolific, contributing 129 publications. Additionally, Levi Marcel was the most frequently co-cited author, appearing 538 times. The journals that published the most articles were SHOCK, CRITICAL CARE MEDICINE, and PLOS ONE, accounting for 10.79 % of the total. The current emerging hotspots are concentrated on "endothelial glycocalyx," "NLRP3 inflammasome," "extracellular vesicle," "biomarkers," and "COVID-19," among others. In conclusion, this study provides a comprehensive overview of the scientific productivity and emerging research trends in the field of ECs in sepsis. The evidence supporting the significant role of ECs in both physiological and pathological responses to sepsis is continuously growing. More in-depth studies of the molecular mechanisms underlying sepsis-induced endothelial dysfunction and EC-targeted therapies are warranted in the future.
    Keywords:  Bibliometric; Endothelial cells; Endothelium; Glycocalyx; Permeability; Sepsis
    DOI:  https://doi.org/10.1016/j.heliyon.2023.e23599
  19. Environ Sci Pollut Res Int. 2024 Jan 06.
      The sun-induced chlorophyll fluorescence (SIF) has received increasing attention over the past few years. This scientometric study analyzed the SIF research field, based on publications available in Web of Science Core Collection visualization, and cluster analysis enabled us to map the knowledge domain and intellectual landscape of this field and identify thematic trends, landmark articles, and emerging research themes. In this study, the software VOSviewer and CiteSpace were used to identify the intellectual base and research front using visualization and analysis. Then, we analyzed synthesized networks of co-authorship (author, institution, and country), co-citation (author, document, and journal), and co-occurring keywords. SIF has increased its publication output steadily since 2002. This study provided a visual knowledge map of the major research domains of SIF. Also, explanations and implications of the findings were explored, and the emerging trends were identified. This report provides a thorough overview of the current state and growth trends of SIF research, and it helps researchers and practitioners understand the major areas of attention in this area and provides insights into prospective areas for further study.
    Keywords:  Remote sensing; Scientometric; Sun-induced chlorophyll fluorescence; Visualization
    DOI:  https://doi.org/10.1007/s11356-023-31709-9
  20. J Environ Manage. 2024 Jan 01. pii: S0301-4797(23)02759-7. [Epub ahead of print]351 119971
      Phytoremediation is an environmentally friendly, economical, and sustainable technique for restoring farmland. It can remove heavy metals and organic pollutants from the soil through the implementation of hyperaccumulator plants. In recent years, it has garnered significant interest from academic and industrial sectors. This article screened 368 research papers from the Web of Science core collection database related to farmland phytoremediation and conducted a bibliometric analysis of the domain based on CiteSpace. The paper intuitively demonstrates the most influential countries, the most productive institutions, the most contributing groups of authors, and the primary sources of farmland phytoremediation research domain. The findings additionally indicate that the research hotspots include: (1) mechanisms and principles of phytoremediation, (2) the improvement of restoration efficiency, (3) the economic, ecological, and sustainable development of phytoremediation. The exploration of plants with potential to accumulate heavy metals and produce large amounts of biomass is the research frontier within the field of farmland phytoremediation. Additionally, this bibliometric analysis can help scholars willing to work in this research field by concisely understanding the overall research field and frontiers. With the continuous improvement of phytoremediation and its combination with other remediation technologies, the future of farmland remediation will have a promising prospect.
    Keywords:  Bibliometric analysis; CiteSpace; Farmland; Phytoremediation
    DOI:  https://doi.org/10.1016/j.jenvman.2023.119971
  21. Medicine (Baltimore). 2024 Jan 05. 103(1): e36841
       BACKGROUND: The prevalence of obesity is gradually increasing and is closely associated with hypothyroidism. It is of research interest to explore the association between obesity and hypothyroidism and the current status of research.
    METHODS: We chose the Web of Science Core Collection (WoSCC) database as the data source and searched to obtain relevant literature on obesity and hypothyroidism. And we used CiteSpace and VOSviewer to analyze the related literature.
    RESULTS: A total of 508 articles were included in the literature, with an overall increasing trend in the number of publications. There were 170 relevant countries or organizations, and the United States was the country with the most publications. There were 1742 related organizations, and the Egyptian Knowledge Bank (EKB) was the organization with the most publications. There are 3015 authors involved, and there is a clear collaboration between authors. There are 227 related journals and J CLIN ENDOCR METAB is the most cited journal. The most frequently occurring keywords were obesity and hypothyroidism, but also other related topics such as bariatric surgery, metabolic syndrome, insulin resistance, body mass index, and leptin.
    CONCLUSION: The research related to obesity and hypothyroidism is gradually gaining attention, and the research direction is gradually expanding to metabolic syndrome, insulin resistance, leptin, and other related topics.
    DOI:  https://doi.org/10.1097/MD.0000000000036841
  22. J Hip Preserv Surg. 2023 Aug-Dec;10(3-4):10(3-4): 181-191
      Bernese periacetabular osteotomy (PAO) is a practical and safe acetabular reorientation technique used to correct structural hip deformities, and much relevant literature has been published over the past decades. This bibliometric study aims to determine the status of PAO research between 1994 and 2022. Information about PAO research publications from 1994 to 2022 was obtained from the Web of Science Core Collection. This bibliometric study is implemented and analyzed through three bibliometric tools with respect to publication counts, countries, institutions, authors, journals, funding agencies, references and keywords. In total, 634 publications concerning PAO were identified. The United States and Washington University in St. Louis have published the most literature in terms of country and institution. Additionally, Switzerland and the University of Bern are the country and the institution with the highest average number of citations in the PAO field. The most published and co-cited journal is Clinical Orthopaedics and Related Research. Burst keyword detection has discovered that 'patient-reported outcome', 'instability', 'risk', 'survivorship' and 'outcome' are regarded as the current research frontier. In summary, our findings provide insight into the bibliometric overview of research status in the PAO field, which may offer later investigators' references in exploring further research directions.
    DOI:  https://doi.org/10.1093/jhps/hnad038
  23. Front Pediatr. 2023 ;11 1269736
       Background: Chemotherapy is an important treatment for children with cancer, and chemotherapy-induced pain is an important role in affecting patients' quality of life. In our study, bibliometric analysis was used to identify current research hotspots and future research trends of chemotherapy and pain in children over the last decade. Our findings can provide a reference for the research in the field of chemotherapy and pain in children.
    Method: Publications of chemotherapy and pain in children were collected from the Web of Science Core Collection database. CiteSpace was used to analyze publication characteristics from 2013 to 2022.
    Results: We identified 1,130 eligible publications in the field of chemotherapy and pain in children, with an increasing trend of publications over the last decade. In the field of chemotherapy and pain in children, the United States had the most publication with 346, followed by China with 135. The author with the most published papers was Pamela S Hinds (n = 8) from the United States. The journals that published the most papers were the Journal of pediatric hematology oncology (n = 44) and Medicine (n = 44). The Journal of Clinical Oncology was cited the most frequency (n = 422). St. Jude Children's Research Hospital had the most publication (n = 23). The specific keywords related to the field of chemotherapy and pain in children were "children", "chemotherapy", "management", "childhood cancer", "randomized controlled trial" and "efficacy". Emerging research focuses predominantly on symptomatic and supportive interventions for chemotherapy and pain in children.
    Conclusion: Attention to chemotherapy and pain in children with cancer was insufficient. This bibliometric analysis showed the upward trend of chemotherapy and pain in children over the last decade. More studies are needed to improve the quality of life in children with chemotherapy-induced pain. This study may provide useful information to guide future research on chemotherapy and pain in children.
    Keywords:  CiteSpace; cancer; chemotherapy; children; pain
    DOI:  https://doi.org/10.3389/fped.2023.1269736
  24. Environ Sci Pollut Res Int. 2024 Jan 03.
      New energy vehicle (NEV) policies involve extensive and complex aspects. NEV policies have been an important issue of academic interest in the academic research community. The current research of the NEV policy has the key significance of inducing experience and guiding the future. This study conducts a comprehensive bibliometric analysis through quantitative research methods to summarize the development and evolution of NEV policy in recent years. Using Citespace visualization tools, we reviewed 2919 papers collected from the Web of Science, identified three stages in the development of the research field, and summarized features relevant to the policy in history. The most influential countries, institutions, authors, keywords, and references have been examined. Through burst detection and cluster analysis, we analyzed historical trends and trajectories in this area of research. In the data we collected, a number of indicators are related to China, indicating that China's NEV policy has a representative significance in the field of NEV policy research. Consequently, we further collected the relevant research from China, in order to summarize the policy reasons behind the rapid development of NEVs in China, and help researchers to have a better understanding of the frontiers of NEVs.
    Keywords:  Citespace; Knowledge mapping; New energy vehicle policy; Visualization
    DOI:  https://doi.org/10.1007/s11356-023-31485-6
  25. Eur Rev Med Pharmacol Sci. 2023 Dec;pii: 34807. [Epub ahead of print]27(24): 12088-12102
       OBJECTIVE: Janus Kinase (JAK) inhibitors have been extensively evaluated for their potential in the management of various diseases. Despite previous research on this topic, there is a lack of bibliometric analysis that summarizes research trends on JAK inhibitors. This study aims to provide a comprehensive overview of the top 100 most frequently cited studies on JAK inhibitors over the last ten years.
    MATERIALS AND METHODS: The Web of Science database was used to screen and extract relevant studies on JAK inhibitors. The top 100 studies most cited within the JAK inhibitor-related research were identified and evaluated, and various data such as the year of publication, study focus and keywords, author information, and number of citations were extracted and analyzed for further examination.
    RESULTS: In the top 100 most cited studies of JAK inhibitors, more than 70% of studies focused on the role of JAK inhibitors in disease treatments, with 42% of these studies focused on using JAK inhibitors as treatment for autoimmune diseases and 19 of them focused on the treatment of neoplasms. Time trend analysis revealed that the keywords "tofacitinib", "atopic dermatitis", and "rheumatoid arthritis" were widely mentioned in 2016, while new trends emerged in 2018, with "ruxolitinib" and "baricitinib" being more commonly mentioned.
    CONCLUSIONS: The top 100 most frequently cited studies on JAK inhibitors focused primarily on the safety and efficacy of these inhibitors in the management of various diseases, particularly inflammatory diseases and neoplasms. The results can serve as a valuable reference for rheumatologists and immunologists interested in the development of JAK inhibitors and expanding future research fields.
    DOI:  https://doi.org/10.26355/eurrev_202312_34807
  26. J Integr Neurosci. 2023 Oct 23. 22(6): 140
       BACKGROUND: Perioperative neurocognitive disorder (PND) is a general term for cognitive impairment that negatively affects multiple domains, including memory, concentration, and physical functioning. Numerous articles have been published on PND; however, only a few quantitative analyses covering this disorder have been published.
    METHODS AND MATERIALS: To clarify PND's developmental history, research foci, and future directions, we conducted a bibliometric analysis using the bibliometric tools VOSviewer and CiteSpace. A total of 4704 publications were obtained from the Web of Science database, including annual publications and trends, keywords, institutions, journals, and collaboration between countries/regions and authors.
    RESULTS: In addition, we found that neuroinflammation is a hotspot in recent studies.
    CONCLUSIONS: This bibliometric analysis provides a broad overview of studies in the field of PND.
    Keywords:  bibliometric analysis; neuroinflammation; perioperative neurocognitive disorder; postoperative cognitive dysfunction; research trend
    DOI:  https://doi.org/10.31083/j.jin2206140
  27. Eur Rev Med Pharmacol Sci. 2023 Dec;pii: 34794. [Epub ahead of print]27(24): 11947-11960
       OBJECTIVE: The number of studies in the field of andrology is increasing day by day, but a bibliometric study covering the entire literature on andrology has not yet been conducted. This bibliometric study aims to shed light on the question of where we came from and where we are going in andrology from past to present. It also aimed to summarize the intellectual structure of andrology to reveal global productivity and identify and map the latest trends of scientific articles published in the field of andrology.
    MATERIALS AND METHODS: 16,659 articles published between 1980 and 2022 were extracted from the Web of Science and analyzed using various statistical methods. Bibliometric network visualization maps revealed trending topics, global productivity, the most influential studies, and international collaborations. Spearman's correlation analysis was used for determining correlations.
    RESULTS: The top three productive countries were United States of America (3,452; 20.7%), China (2,300; 13.8%), and Germany (1,069; 6.4%). The top two most productive authors were Agarwal A. (n=130) and Nieschlag E. (n=130). The most productive institution was the Egyptian Knowledge Bank (n=422). From past to present, the most studied subjects were testis, male infertility, spermatozoa, testosterone, infertility, erectile dysfunction, spermatogenesis, sperm, prostate cancer (PCA)/neoplasms, oxidative stress, fertility/fertilization, semen, rat(s), apoptosis, azoospermia, sperm motility, human and varicocele.
    CONCLUSIONS: The trend topics that have been researched more in recent years include erectile dysfunction, oxidative stress, prostate cancer, sperm quality, sperm parameters, infertility, premature ejaculation, diabetes mellitus, obesity, prognosis, sperm DNA fragmentation/damage, antioxidant, asthenozoospermia, varicocelectomy, COVID-19, inflammation, prostatectomy, metabolic syndrome, hypogonadism, benign prostatic hyperplasia, lower urinary tract symptoms, meta-analysis, sexual dysfunction, peyronie's disease, and proliferation. We identified the research leadership of China, Japan, Turkey and India, in addition to Western countries, such as the USA and European countries.
    DOI:  https://doi.org/10.26355/eurrev_202312_34794
  28. Cureus. 2023 Nov;15(11): e49700
      Electrical impedance tomography (EIT) is a gradually maturing medical imaging technique that relies on computational algorithms for reconstructing and visualizing internal conductivity distributions within the human body. To provide a comprehensive and objective understanding of the current state and trends in the EIT algorithm research, we conducted bibliometric analysis on a 25-year EIT algorithm research dataset sourced from Web of Science Core Collections. We visualized publication characteristics, collaboration patterns, keywords, and co-cited references. The results indicate a steady increase in annual publications over recent decades. The United States, United Kingdom, China, and South Korea contributed 60% of the articles collaboratively. Keyword analysis unveiled three distinct stages in the evolution of EIT algorithm research: the establishment of fundamental algorithm frameworks, optimization for improved imaging performance, and the development of algorithms for clinical applications. Additionally, there has been a shift in research focus from traditional theories to the incorporation of new methods, such as artificial intelligence. Co-cited references suggest that integrating EIT with other established imaging techniques may emerge as a new trend in EIT algorithm research. In summary, EIT algorithms have been a consistent research focus, with current efforts centered on optimizing algorithms to enhance imaging performance. The emerging research trend involves utilizing more diverse and intersecting algorithms.
    Keywords:  algorithm; bibliometric analysis; eit; hotspot; woscc
    DOI:  https://doi.org/10.7759/cureus.49700
  29. PLoS One. 2023 ;18(12): e0294669
      Self-citations are a key topic in evaluative bibliometrics because they can artificially inflate citation-related performance indicators. Recently, self-citations defined at the largest scale, i.e., country self-citations, have started to attract the attention of researchers and policymakers. According to a recent research, in fact, the anomalous trends in the country self-citation rates of some countries, such as Italy, have been induced by the distorting effect of citation metrics-centered science policies. In the present study, we investigate the trends of country self-citations in 50 countries over the world in the period 1996-2019 using Scopus data. Results show that for most countries country self-citations have decreased over time. 12 countries (Colombia, Egypt, Indonesia, Iran, Italy, Malaysia, Pakistan, Romania, Russian Federation, Saudi Arabia, Thailand, and Ukraine), however, exhibit different behavior, with anomalous trends of self-citations. We argue that these anomalies should be attributed to the aggressive science policies adopted by these countries in recent years, which are all characterized by direct or indirect incentives for citations. Our analysis confirms that when bibliometric indicators are integrated into systems of incentives, they are capable of affecting rapidly and visibly the citation behavior of entire countries.
    DOI:  https://doi.org/10.1371/journal.pone.0294669
  30. Int J Med Sci. 2024 ;21(1): 151-168
      Background: Ischemic stroke is a common cerebrovascular accident with a high risk of neurological deficits. Stem cell therapy has progressively attracted the interest of scientists and clinicians due to the benefits of promoting neural regeneration and regulating the microenvironment surrounding the lesion after ischemic stroke. Our study aimed to evaluate the development trends and research hotspots in the field of stem cells and ischemic stroke. Materials and methods: Publications related to stem cells and ischemic stroke were retrieved from the Web of Science from 2001 to 2022. Data analysis and mapping were performed using VOSviewer, Citespace and ImageGP. Results: In total, 1932 papers were included in the analysis. Publications have steadily increased over the past 22 years. China has contributed the maximum number of publications, whereas the USA ranked first in the total number of citations and was considered the center of the international collaboration network. University of South Florida, Henry Ford Hospital, and Oakland University were the most influential institutions. Stroke, Brain Research, and Neural Regeneration Research were the most productive journals. The research in this field was primarily focused on the effects of stem cells on neurogenesis, inflammation, and angiogenesis following ischemic stroke, as well as their therapeutic potential for the disease. In addition, neural stem cells and mesenchymal stem cells are the most commonly utilized stem cells. The topics related to miRNA, extracellular vesicles, exosomes, mesenchymal stem cells, neuroinflammation, and autophagy are current research hotspots. Conclusion: Our bibliometric study provides a novel perspective on the research trends in the field of stem cells and ischemic stroke. The outcome of this study may benefit scientists to identify research hotspots and development directions, thereby advancing the application of stem cell-based therapy for ischemic stroke.
    Keywords:  Bibliometric analysis; Ischemic stroke; Neurogenesis; Paracrine effects; Stem cells; Translation.
    DOI:  https://doi.org/10.7150/ijms.86591
  31. Ann Transplant. 2024 Jan 02. 29 e942074
      BACKGROUND Malignancy after kidney transplantation (MKT) remains a leading cause of death in transplant recipients and over the past few decades there have been many reports on this topic. However, the task of extracting crucial information from intricate events poses a significant challenge in guiding clinical work. Hence, bibliometrics was employed to summarize and predict the future in this study. MATERIAL AND METHODS Reviews and articles on MKT were extracted from the Web of Science Core Collection (WoSCC) and were analyzed by the software VOSviewer, CiteSpace, Scimago Graphica, and R package Bibliometrix for bibliometric analysis. RESULTS The analysis considered 5700 publications from 28 647 authors and 4924 institutions across 100 countries, spanning the years 1970-2022. Reference co-citation analysis showed that "renal cell carcinoma", "skin cancer", "post-transplant lymphoproliferative disorder" and "COVID-19 vaccine" were research hotspots. Keywords that co-occurred early were "immunosuppressant", "cancer", "Epstein-Barr virus", "squamous cell carcinoma", and "infection", etc., while "impact","risk factor", "outcomes", "mortality", "management" frequently co-occurred later. From 2020 to 2022, newly emerging keywords such as "SARS-CoV-2" and "COVID-19", together with citation bursts for "immune checkpoint inhibitors" and "ipilimumab," were observed. CONCLUSIONS The focus of MKT-related studies has evolved from exploring the spectrum, risk factors, and outcomes of MKT, to examining the pathogenesis, individualized screening, prevention, and treatment, including appropriate use of immune checkpoint inhibitors. Reports of renal transplant recipients infected with SARS-CoV-2 or COVID-19 have also gained attention since 2019. These suggest that individualized management remains a frontier for research and a future direction in MKT topics.
    DOI:  https://doi.org/10.12659/AOT.942074
  32. Endocr Metab Immune Disord Drug Targets. 2024 Jan 04.
       BACKGROUND: Thyroid nodules are common lesions in benign and malignant thyroid diseases. More and more studies have been conducted on the feasibility of artificial intelligence (AI) in the detection, diagnosis, and evaluation of thyroid nodules. The aim of this study was to use bibliometric methods to analyze and predict the hot spots and frontiers of AI in thyroid nodules.
    METHODS: Articles on the application of artificial intelligence in thyroid nodules were retrieved from the Web of Science core collection database. A website (https://bibliometric.com/), VOSviewer and CiteSpace software were used for bibliometric analyses. The collaboration maps of countries and institutions were analyzed. The cluster and timeline view based on cocitation references and keywords citation bursts visualization map were generated.
    RESULTS: The study included 601 papers about AI in thyroid nodules. China contributed to more than half (52.41%) of these publications. The cluster view and timeline view of co-citation references were assembled into 9 clusters, "AI", "deep learning", "papillary thyroid carcinoma", "radiomics", "ultrasound image", "biomarkers", "medical image segmentation", "central lymph node metastasis (CLNM)", and "self-organizing auto-encoder". The "AI", "radiomics", "medical image segmentation", "deep learning," and "CLNM", emerging in the last 10 years and continuing until recent years, were included.
    CONCLUSION: An increasing number of scholars were devoted to this field. The potential future research hotspots include risk factor assessment and CLNM prediction of thyroid carcinoma based on radiomics and deep learning, automatic segmentation based on medical images (especially ultrasound images).
    Keywords:  Artificial intelligence; Bibliometrics; Lymph node metastasis; Radiomics; Risk factor; Thyroid Nodule
    DOI:  https://doi.org/10.2174/0118715303264254231117113456
  33. Clin Rheumatol. 2024 Jan 06.
       BACKGROUND: Melanoma differentiation-associated gene 5 (MDA5), as a cytoplasmic sensor for viral double-stranded RNAs, has received increasing attention in recent years. Although considerable headway has been made on the functional role of MDA5 in antiviral immunity and autoimmune disease, the available literature is insufficient to assess the vast field.
    METHODS: This study performed a bibliometric analysis to investigate current hotspots in the global scientific output of MDA5 over the past two decades. Related publications and recorded information from 2002 to 2022 in the Web of Science Core Collection (WoSCC) database were retrieved. VOSviewer and CiteSpace were used for quantitative evaluation and visualization.
    RESULTS: A total of 2267 original articles and reviews were obtained, and the annual number of publications related to MDA5 was increasing rapidly. China has published the most papers, while the USA was the most influential country with the most citations and the highest H-index. The Chinese Academy of Sciences, the United States Department of Health and Human Services, and the Journal of Virology were the most prolific research affiliation, funding source, and journal, respectively. Fujita T (Kyoto University) was the most productive author with the highest H-index and had close cooperation with Kato H and Yoneyama M. The keywords "RIG-I," "MDA5," "innate immunity," "double-stranded-RNA," and "recognition" had the highest frequency, while "dermatomyositis" as well as "autoantibody" seemed to be the emerging hotspots.
    CONCLUSION: This study comprehensively demonstrated the research frontiers of MDA5 and will provide a useful resource for scholars to conduct future decisions.
    KEY POINTS: We conducted the first in-depth survey of the research frontiers on melanoma differentiation-associated gene 5 (MDA5) over the past two decades via bibliometric analysis. We found that many early breakthroughs have been made in the mechanism of MDA5-mediated antiviral immune responses, and the role of MDA5 in autoimmune and autoinflammatory diseases has raised the recent concern. We identified that the virus infection-associated pathogenesis and effective therapeutic strategy of anti-MDA5 antibody-positive dermatomyositis will remain the hotspots in the future.
    Keywords:  Bibliometrics; Dermatomyositis; Innate immunity; MDA5
    DOI:  https://doi.org/10.1007/s10067-023-06851-x
  34. Heliyon. 2024 Jan 15. 10(1): e22853
      Netnography is a special kind of qualitative social media research. It applies ethnographic techniques to comprehend social interaction in settings of modern digital communications. This article aims to highlight the key contributors and knowledge structure of this research domain. Utilizing bibliographic data of 722 articles retrieved from the Scopus database, researchers used performance analysis to have insights into the most prolific authors, institutions, countries and journals. Keywords co-occurrence analysis was done to map the knowledge structure. The thematic map tool was used to recognize basic themes, motor themes, niche themes, and emerging themes in order to suggest future research directions. The results indicate that, in terms of research publications, the most productive nation is the United Kingdom. The most lucrative organization has been acknowledged as Griffith University. The most influential author is stated to be Mkono M. The most resourceful source is Journal of Business Research. In addition, three significant knowledge clusters important to study utilizing netnography were identified as a result of co-occurrence of keywords analysis namely, consumer behaviour, co-creation in online brand communities and authenticity. Further, niche and emerging themes include-sustainable tourism, customer engagement and sharing economy. When taken as a whole, this review is a useful tool for quickly understanding the most recent research findings and potential directions for further investigation. An assessment of the state of netnography in business and management research has not been systematically investigated. Hence, the present study aims to thorough a grasp of the state-of-the-art in Netnography research field over the past decades along with the future research directions. Studying the state of the art in the field adds to academic knowledge and provides updated information on the procedure.
    Keywords:  Bibliometric; Business research; Ethnography; Netnography
    DOI:  https://doi.org/10.1016/j.heliyon.2023.e22853
  35. Skin Res Technol. 2024 Jan;30(1): e13538
       BACKGROUND: Psoriasis is an immune-mediated chronic inflammatory skin disease. Great progress has been made in the pathogenesis of psoriasis in recent years, but there is no bibliometric study on the pathogenesis of psoriasis. The purpose of this study was to use bibliometrics method to analyze the research overview and hot spots of pathogenesis of psoriasis in recent 10 years, so as to further understand the development trend and frontier of this field.
    METHODS: The core literatures on the pathogenesis of psoriasis were searched in the Web of Science database, and analyzed by VOSviewer, CiteSpace, and Bibliometrix in terms of the annual publication volume, country, institution, author, journal, keywords, and so on.
    RESULTS: A total of 3570 literatures were included. China and the United States were the main research countries in this field, and Rockefeller University was the main research institution. Krueger JG, the author, had the highest number of publications and the greatest influence, and Boehncke (2015) was the most cited local literature. J INVEST DERMATOL takes the top spot in terms of the number of Dermatol articles and citation frequency. The main research hotspots in the pathogenesis of psoriasis are as follows: (1) The interaction between innate and adaptive immunity and the related inflammatory loop dominated by Th17 cells and IL-23/IL-17 axis are still the key mechanisms of psoriasis; (2) molecular genetic studies represented by Long Non-Coding RNA (LncRNA); (3) integrated research of multi-omics techniques represented by gut microbiota; and (4) Exploring the comorbidity mechanism of psoriasis represented by Metabolic Syndrome (MetS).
    CONCLUSION: This study is a summary of the current research status and hot trend of the pathogenesis of psoriasis, which will provide some reference for the scholars studying the pathogenesis of psoriasis.
    Keywords:  CiteSpace; VOSviewer; bibliometrics; pathogenesis; psoriasis
    DOI:  https://doi.org/10.1111/srt.13538
  36. Heliyon. 2024 Jan 15. 10(1): e23542
       Background: It is now understood that T cells play a key role in the occurrence and development of psoriasis. Herein, a bibliometric analysis was conducted to summarize the content and trends of T cell-related research in psoriasis.
    Methods: A bibliometric analysis was conducted on publications pertaining to T cells in psoriasis between 2003 and 2022 retrieved from the Web of Science Core Collection (WoSCC) database using tools such as CiteSpace, the Bibliometrix R package, and VOSviewer.
    Results: The study included a total of 3595 articles authored by 14,188 individuals, including all coauthors in article bylines. The Laboratory for Investigative Dermatology at Rockefeller University, led by James G Krueger, has made significant contributions to this field through focusing on the pathogenesis of psoriasis and exploring the potential of using biological agents to treat psoriasis. Furthermore, targeted inhibitors have significantly impacted the treatment of psoriasis, with researchers focusing on small-molecule targeted drugs as a new area of research that could potentially replace biological agents.
    Conclusions: Research has established the efficacy and long-term safety of targeted inhibition of T cell-related targets. Deucravacitinib, a psoriasis treatment drug targeting TYK2 as an allosteric inhibitor, has attracted significant attention and raised high expectations.
    Keywords:  Bibliometric analysis; Biological agents; Psoriasis; Small-molecule targeted drugs; T cells; Targeted inhibitors
    DOI:  https://doi.org/10.1016/j.heliyon.2023.e23542
  37. Arthrosc Sports Med Rehabil. 2024 Feb;6(1): 100838
       Purpose: To assess the future publication rates of abstracts presented at AANA annual meetings between 2015 and 2019.
    Methods: Abstracts presented at the 2015-2019 AANA annual meetings were identified. The PubMed and Google Scholar databases were searched for a corresponding manuscript for each abstract using the name of the first author, abstract title, and keywords. A level of evidence and anatomic category were assigned to each abstract. For each corresponding manuscript identified, the authors, journal of publication, journal impact factor (IF), time to publication, and number of citations were recorded.
    Results: Overall, 70.5% of abstracts presented at the 2015-2019 AANA annual meetings (275 of 390) went on to future publication, with 63.6% (248 of 390) achieving publication within 3 years. The median time to publication from presentation was 12.8 months. Arthroscopy (29.8%) was the most frequent journal of publication. The average IF of publishing journals was 4.92 ± 3.41, with 61.8% of manuscripts (170 of 275) published in journals with an IF of at least 4.00. Published manuscripts received an average of 36.30 ± 47.6 citations per manuscript. A stronger level of evidence was associated with an increased likelihood of future publication (P = .008).
    Conclusions: Pre-publication literature presented at the AANA annual meetings has continued to be associated with a strong likelihood of future publication in Arthroscopy and Arthroscopy, Sports Medicine, and Rehabilitation, as well as other respected peer-reviewed journals.
    Clinical Relevance: Exposure to pre-publication literature may have an impact on clinical management. It is important to understand the quality of research presented in abstracts from AANA annual meetings. Knowing how many abstracts are ultimately published in peer-reviewed journals provides an indicator of the quality and reliability of the research.
    DOI:  https://doi.org/10.1016/j.asmr.2023.100838
  38. Heliyon. 2024 Jan 15. 10(1): e23405
       Background: According to the World Health Organization (WHO), healthy aging is the process of developing and maintaining the functional capacity for health in old age. A rapidly growing number of research studies on healthy aging have been conducted worldwide. The purpose of this research work is to explore global scientific landscape of healthy aging research over the last 22 years.
    Methods: Scientific publications on healthy aging from January 1, 2000 to October 11, 2022 were retrieved from the Web of Science Core Collection (WoSCC) on October 11, 2022. A total of 6420 publications were included in the scientometric analysis. VOSviewer (1.6.18) was used to conduct scientometric and visualized analysis.
    Results: The publication growth rate was 35.68 from 2000 to 2021. The United States of America (USA) led in both productivity and citations. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA was prominent in terms of both the highest citation count and the highest average citation count. The National Institute on Aging (NIA) and Evans, Michele K. were the most influential organization and author, respectively. Research hotspots in healthy aging were identified based on the co-occurrence analysis of keywords: (1) physical activity and mental health of older adults; (2) diseases impacting the health and lifespan of older adults; and (3) neuroscience. Our analysis indicates that gut microbiota, loneliness, frailty, mitochondria and resilience were the emerging themes in healthy aging research.
    Conclusions: The quantity of annual publications on healthy aging has rapidly increased over the past 22 years, especially during 2018-2021. This analysis identified the status, trends, hot topics, and frontiers of healthy aging research. These findings will help researchers quickly understand the global representation of healthy aging research, influence resource dissemination, promote international collaborations, guide policy formulation, and improve health services for older adults.
    Keywords:  Data visualization; Healthy aging; Older adults; Scientometric analysis; VOSviewer
    DOI:  https://doi.org/10.1016/j.heliyon.2023.e23405
  39. Medicine (Baltimore). 2024 Jan 05. 103(1): e36218
      Rheumatoid arthritis (RA) is a prevalent autoimmune disorder with a significant global economic burden. Epigenetic modifications, particularly DNA methylation, play a crucial role in RA. This study conducted a bibliometric analysis to explore the evolving trends and predominant themes in RA and DNA methylation research over the past two decades. A total of 1800 articles met the inclusion criteria, and the analysis revealed consistent growth in the literature, with a notable increase in output after 2019. The research involved 70 countries, 2139 academic institutions, 23,365 unique authors, and 58,636 co-cited authors. The United States emerged as a dominant contributor in this research domain. The significance of DNA methylation in shaping research directions for RA management is increasingly evident. Recent investigations have shed light on the pivotal role of DNA methylation in RA, particularly in characterizing synovial tissue and exploring the underlying mechanisms of disease pathogenesis. This study provides valuable insights into the landscape of DNA methylation research in RA and highlights the importance of epigenetics in autoimmune diseases.
    DOI:  https://doi.org/10.1097/MD.0000000000036218
  40. J Orthop. 2024 Apr;50 22-28
      Incorporation of three-dimensional (3D) printing technology into the field of spinal surgery is on the rise. A bibliometric analysis of the current topic was carried out to elaborate the trend and to navigate future research. A Scopus database search was conducted with keywords related to 3D printing, spine, and surgery. The final 792 articles were extracted and further analyzed with VOSviewer 1.6.19 and Biblioshiny. The first published article was in 2002. A notable increase in articles in 2014 might be attributable to the availability of cheaper 3D printers which rose significantly on a global scale in 2011. China leads in terms of published research on 3D printing in spinal surgery, followed by the US, Australia, and India. The author's keyword co-occurrence analysis reveals 8 theme clusters, including preoperative and intraoperative measures, biomodelling, spinal neoplasms, biomechanics of 3D-printed materials, degenerative spinal diseases, minimally invasive surgery, and bioprinting. The top 15 of the most recently cited keywords are listed to provide future researchers to produce impactful articles. Two strategic diagrams of 2 periods (2002-2018 and 2018-2023) show the theme's evolution. We found 6 consistent themes in keyword co-occurrence analysis and the strategic diagram analysis, that are promising subjects for future research. Overall, this bibliographic study indicates the expanding importance of 3D printing in spinal surgery and suggests several critical themes and impactful keywords for future researchers.
    Keywords:  Additive manufacturing; Bibliometric study; Review; Spine surgery; Three dimensional printing
    DOI:  https://doi.org/10.1016/j.jor.2023.11.054
  41. Eye (Lond). 2024 Jan 03.
       OBJECTIVES: To compare the performance of a composite citation score (c-score) and its six constituent citation indices, including H-index, in predicting winners of the Weisenfeld Award in ophthalmologic research. Secondary objectives were to explore career and demographic characteristics of the most highly cited researchers in ophthalmology.
    METHODS: A publicly available database was accessed to compile a set of top researchers in the field of clinical ophthalmology and optometry based on Scopus data from 1996 to 2021. Each citation index was used to construct a multivariable model adjusted for author demographic characteristics. Using area under the receiver operating curve (AUC) analysis, each index's model was evaluated for its ability to predict winners of the Weisenfeld Award in Ophthalmology, a research distinction presented by the Association for Research in Vision and Ophthalmology (ARVO). Secondary analyses investigated authors' self-citation rates, career length, gender, and country affiliation over time.
    RESULTS: Approximately one thousand unique authors publishing primarily in clinical ophthalmology/optometry were analyzed. The c-score outperformed all other citation indices at predicting Weisenfeld Awardees, with an AUC of 0.99 (95% CI: 0.97-1.0). The H-index had an AUC of 0.89 (95% CI: 0.83-0.96). Authors with higher c-scores tended to have longer career lengths and similar self-citation rates compared to other authors. Sixteen percent of authors in the database were identified as female, and 64% were affiliated with the United States of America.
    CONCLUSION: The c-score is an effective metric for assessing research impact in ophthalmology, as seen through its ability to predict Weisenfeld Awardees.
    DOI:  https://doi.org/10.1038/s41433-023-02912-2
  42. Cureus. 2023 Nov;15(11): e49714
      The medical profession has experienced a significant increase in the number of women practitioners in recent decades, leading to a reduction in the gender gap. According to the United States Medical Association, approximately 25% of physicians in the United States are now women. Although this progress is evident in the clinical setting, women's representation in academic medicine remains disproportionately low. The underrepresentation of women in academia has various consequences, including limited access to academic resources and hindered career growth. Previous studies have attempted to analyze these disparities, but results have been inconsistent, and the issue's complexity has not been fully understood. This study aims to examine the disparity in the gender of first authors in academic publications related to " Artificial intelligence (AI) and Attention Deficit Hyperkinetic Disorder (ADHD)" between 2010 and 2023. Analysis was conducted on June 21st, 2023, using the database PubMed. The search term "AI" AND "ADHD" was used to derive all articles over a period of 13 years, from January 1st, 2010, to December 31st, 2022, excluding the year 2023 due to limited available publications. The relevant articles were downloaded in Microsoft Excel sheets. The gender of the first authors was determined using the NamSor app V.2, an application programming interface (API) with a large dataset of names and countries of origin. A total of 204 articles were considered for this study. There were 78 female first authors and 126 male first authors. The highest number of publications with a male first author occurred in 2022, with 32 publications. The Netherlands, Singapore, Turkey, and China have the highest gender ratios, indicating a more favourable representation of both genders. The p-value of 0.2664 suggests that there is no significant association between gender and country. The findings revealed a gender disparity, with a higher number of male first authors. By addressing and rectifying these disparities, we can enhance the overall quality, diversity, and inclusivity of research in the field of ADHD and Artificial Intelligence.
    Keywords:  adhd; artificial intelligence; first authors; gender disparities; gender equality; gender parity; gender trends; inclusivity; publications
    DOI:  https://doi.org/10.7759/cureus.49714
  43. Heliyon. 2024 Jan 15. 10(1): e23041
       Background: As an important monitoring index for adaptation to hypoxia, sleep may reflect the adaptive state of the body at high altitudes. The literature has shown a link between altitude and sleep problems, and sleep changes have become a common problem for individuals at high altitudes, negatively impacting their physical and mental health. As research on high-altitude sleep has gained attention in recent years, the publishing volume has increased worldwide, necessitating a more comprehensive understanding of this field. This manuscript evaluates the key themes and emerging trends in high-altitude sleep over the past few decades and predicts future research directions.
    Methods: Articles related to high-altitude sleep published from 1992 to 2022 were retrieved from the Web of Science Core Collection, and the relevant literature characteristics were extracted after the screening. Then, bibliometric analyses and visualizations were performed using Microsoft Excel, CiteSpace, VOSviewer, and an online analysis platform (http://bibliometric.com).
    Results: A total of 1151 articles were retrieved, of which 368 were included in the analysis, indicating a gradually increasing trend. The United States, Switzerland, and China have made significant contributions in this field. Bloch KE from the University of Zurich was determined to be the most productive and academically influential author in this field. The highest-yielding journal was High Altitude Medicine & Biology. Initially, altitude training was the primary research topic. Currently, research focuses on sleep disorders and sleep apnea. In the coming years, keywords such as "sleep quality," "prevalence," and "obstructive sleep apnea" will attract more attention.
    Conclusion: Our findings will assist scholars to better understand the intellectual structure and emerging trends in this field. Future developments in high-altitude sleep research are highly anticipated, particularly in terms of sleep quality at high altitudes and its associated prevalence. This research is also crucial for the improvement and treatment of symptoms during nocturnal sleep in patients with chronic hypoxia due to cardiopulmonary diseases at high altitudes.
    Keywords:  Altitude; Bibliometric; CiteSpace; Hypoxic; Sleep; VOSviewer
    DOI:  https://doi.org/10.1016/j.heliyon.2023.e23041
  44. Imaging Sci Dent. 2023 Dec;53(4): 335-344
       Purpose: This bibliometric analysis aimed to provide a comprehensive overview of the characteristics, trends, and level of diagnostic efficacy of studies on cone-beam computed tomography (CBCT) published in Imaging Science in Dentistry (ISD) from 2011 to 2022.
    Materials and Methods: Publications related to CBCT identified in the electronic collection of ISD were selected according to eligibility criteria by 2 independent reviewers who collected data on the characteristics of the articles (year, authors, and country). The type and topic of studies were analyzed using VOSviewer v.1.6.18 (Centre for Science and Technology Studies, Leiden University, Leiden, Netherlands). The research articles were classified according to the hierarchical scale of diagnostic efficacy.
    Results: Of the 236 articles included, most were from South Korea and Brazil. Bong-Hae Cho and Yun-Hoa Jung were the most prolific authors on the topic of CBCT. The most frequently published types of studies were cross-sectional and laboratory-based. The most popular topics WERE related to the diagnosis of pathologies and/or alterations, as well as anatomical variations. On the diagnostic efficacy scale, most studies were rated level 1 (technical efficacy) or 2 (diagnostic accuracy efficacy).
    Conclusion: A steady increase was observed in publications related to CBCT, which are of both clinical and academic interest. The trends in these publications were analyzed, revealing that most are cross-sectional studies primarily exploring the capabilities of CBCT in diagnosing pathologies and/or changes in the oral and maxillofacial complex. These studies were typically classified as level 1 or 2 on the diagnostic efficacy scale.
    Keywords:  Bibliometrics; Cone-Beam Computed Tomography; Diagnostic Imaging; Research
    DOI:  https://doi.org/10.5624/isd.20230106
  45. Medicine (Baltimore). 2024 Jan 05. 103(1): e36706
       BACKGROUND: Leading scientists worldwide are recognized by their placement in the top 2% based on their career-spanning contributions, as categorized by the Science-Metrix classification. However, there has been little focus on the unique scientific fields and subfields that separate countries. Although the KIDMAP in the Rasch model has been utilized to depict student performance, its application in identifying distinctive academic areas remains unexplored. Our study uses this model to pinpoint unique research domains specific to countries based on the top 2% author data.
    METHODS: We sourced our data from Elsevier career-long author database updated until the end of 2022. This encompassed 168 countries, 22 scientific domains, and 174 subdomains in 2021 and 2022 (with a total of 194,983 and 204,643 researchers, respectively). Our approach was threefold: identifying unique fields, subfields, and researchers. Visualizations included scatter plots, KIDMAP, and the Impact Bam Plot (IBP). China distinctive research areas were identified using the Rasch KIDMAP.
    RESULTS: Key insights include the following: The US prevailing dominance in scientific domains in both 2021 and 2022. China distinct contribution in the "Enabling & Strategic Technologies" domain. China notable emphasis on the "Complementary & Alternative Medicine" subfield in 2022. Dr Phillip Low from the Mayo Clinic (US) emerged as a leading figure in the General & Internal Medicine research domain.
    CONCLUSIONS: Despite trailing the US in global research achievements, China showcased pronounced expertise in specific scientific areas, such as the "Complementary & Alternative Medicine" subfield in 2022, when compared to China other subfields based on the level of academic performance (-3.09 logits). Future research could benefit from incorporating KIDMAP visuals to gauge other countries' strengths in various research sectors, expanding beyond the China-centric focus in this study.
    DOI:  https://doi.org/10.1097/MD.0000000000036706
  46. J Multidiscip Healthc. 2023 ;16 4279-4291
       Background: Currently, the psychological problems of stroke patients are of great concern. It is a hot topic of clinical care research to analyze and discuss the current status and hot spots, frontiers and development trends of research on psychological distress of stroke patients, and to develop and implement psycho-social care programs to improve the quality of life of patients.However, there is an absence of visual overviews to assess the published literature systematically.
    Methods: The Web of Science (WOS) database was used to search the relevant literature in this field, spanning the period 2009-2023, and the countries, institutions, and research keywords in this field were visualized and analyzed by CiteSpace analysis software.
    Results: An analysis of 416 papers found that the overall trend of psychological distress in stroke patients was increasing, and the research hotspots were mainly focusing on the relationship between different risk factors and psychological distress in stroke patients, psychological distress in stroke caregivers, positive psychology in stroke patients, and interventions on psychological distress in stroke patients. In the future, the research population may gradually shift to stroke caregivers, and the research focus will be on developing and studying scales.
    Conclusion: Visual analysis of psychological distress studies in stroke patients can provide strategies for clinical interventions and broaden thinking about clinical care.
    Keywords:  Citespace; emotional distress; psychological distress; stroke; visualization analysis
    DOI:  https://doi.org/10.2147/JMDH.S434201
  47. Environ Sci Pollut Res Int. 2023 Dec 29.
      Guilin is a typical representative of karst landform in South China. Because of its unique geographical landform and hydrological environment, Lijiang River Basin has received a certain degree of attention in field of ecology and sustainable development. Explore and visualize the hotspots and frontiers of Guilin Lijiang River Basin Ecology and Sustainable Development (GLRBESD) by using bibliometrics, CiteSpace, and VOSviewer. Results showed that number of published papers was in a fluctuating upward trend from 1992 to 2022 and from 2011 to 2022, respectively. Work of scholars in this field has been continuously strengthened and deepened, and overall scientific research results show an increasing trend. Research objects and topics are mainly aimed at the water resources, climate, and environment of GLRB Landscape ecology and SDG index construction. Research of GLRBESD-published documents has the characteristics of multi-disciplinary and interdisciplinary integration. High-frequency keywords in research field focus on ecotourism, ecological restoration, and sustainable development, mainly based on the research of ecotourism development. Impact of environmental factor changes and human activities on land use change in different periods is an important research topic. Core research field of GLRBESD on macro-scale can be divided into ESV and function, ecological compensation and ecotourism, ecological environment and ecological restoration, ecological network and ecological risk assessment, and sustainable development. This research provides systematic scientific research basis for enhancing sustainable development ability and ecosystem functions and services of World Natural Heritage Site.
    Keywords:  Bibliometrics; Citespace; Guilin; Knowledge map; Lijiang River Basin; Vosviewer
    DOI:  https://doi.org/10.1007/s11356-023-31614-1
  48. Front Pediatr. 2023 ;11 1318690
       Introduction: Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) is a network fostering clinical research to optimize care for critically ill children. We aim to examine the efforts of the PALISI Network to increase gender parity in research, as evidenced by authorship.
    Methods: The first and senior authors of all published PALISI articles from 2002 to 2021 were analyzed for gender of presentation. Funding sources, impact factors, professional roles, and location were extracted.
    Results: We identified 303 articles, 61 published from 2002 to 2011, and 242 from 2012 to 2021. There were 302 first authors, representing 188 unique individuals, and 283 senior authors, representing 119 unique individuals. Over half (55.6%, n = 168) of the first authors were women. More women were first authors from 2012 to 2021 (n = 145, 60.2%) as compared to the years 2002-2011 [37.7%, n = 23, OR = 2.50 (95% CI: 1.40, 4.45, p = 0.002)]. Senior authors were 36.0% (n = 102) women, with no change over time. Women senior authors had a higher proportion of women first authors (67.7% vs. 32.4%, p = 0.017). No gender differences were noted based on article type or impact factor. The majority of authors came from institutions in the United States. Women had comparatively more NIH and CDC funding but received less funding from foundations and AHRQ.
    Discussion: In PALISI publications, first authorship by women has increased over time, such that it now exceeds both the proportion of women pediatric intensivists and women first authors in critical care publications. Senior authorship by women has been stagnant. A multifactorial approach by individuals, institutions, networks, and journals is needed to bring senior women authors to parity.
    Keywords:  authorship; critical care; diversity; equity; inclusion; pediatrics; publications
    DOI:  https://doi.org/10.3389/fped.2023.1318690
  49. Curr Pharm Teach Learn. 2024 Jan 02. pii: S1877-1297(23)00332-5. [Epub ahead of print]
       BACKGROUND: Objective structured clinical examinations (OSCEs) remain an integral part of pharmacy education. This study aimed to characterize key researchers, areas, and themes in pharmacy education OSCEs using a bibliometric review with content analysis.
    METHODS: A bibliometric review was conducted on literature from over 23 years from January 2000 to May 2023. Articles focusing on any type of OSCE research in pharmacy education in both undergraduate and postgraduate sectors were included. Articles were excluded if they were not original articles or not published in English. A summative content analysis was also conducted to identify key topics.
    RESULTS: A total of 192 articles were included in the analysis. There were 242 institutions that contributed to the OSCE literature in pharmacy education, with the leading country being Canada. Most OSCE research came from developed countries and were descriptive studies based on single institution data. The top themes emerging from content analysis were student perceptions on OSCE station styles (n = 98), staff perception (n = 19), grade assessment of OSCEs (n = 145), interprofessional education (n = 11), standardized patients (n = 12), and rubric development and standard setting (n = 8).
    IMPLICATIONS: There has been a growth in virtual OSCEs, interprofessional OSCEs, and artificial intelligence OSCEs. Communication rubrics and minimizing assessor variability are still trending research areas. There is scope to conduct more research on evaluating specific types of OSCEs, when best to hold an OSCE, and comparing OSCEs to other assessments.
    Keywords:  Bibliometric review; OSCEs; Pharmacy education
    DOI:  https://doi.org/10.1016/j.cptl.2023.12.028
  50. Hum Cell. 2023 Dec 30.
      Bronchopulmonary dysplasia (BPD) is a prevalent lung disease in neonates that is associated with numerous complications and high mortality. The promising approach to treat BPD is the use of mesenchymal stem cells (MSCs), However, the current treatment of MSCs presents safety concerns, including occlusion of blood vessels and tumorigenicity. In this study, relevant publications from the Web of Science Core Collection were downloaded in January 2023. The acquired data were analyzed and predicted for trends and hotspots in this field using CiteSpace software. Results revealed that in recent years, the focus of co-cited references has been primarily on the clinical studies of MSCs and the application of MSCs derivatives for treating BPD models. The keywords that have gained attention are extracellular vesicles and exosomes. The United States has emerged as the most influential co-authoring country in this field. Among the co-cited journals, the American Journal of Respiratory and Critical Care Medicine holds the highest influence. Thus, this study provides trends in publications, collaboration, research interests, and hotspots, and provides clues for novel ideas and strategies in to further MSCs treatments for BPD.
    Keywords:  Bronchopulmonary dysplasia; CiteSpace; Exosomes; Extracellular vesicles; Mesenchymal stem cells
    DOI:  https://doi.org/10.1007/s13577-023-01018-x
  51. PLoS One. 2024 ;19(1): e0296421
      Psychological researchers often identify with psychological disciplines, such as social or clinical psychology. The current study analyzed Google Scholar profiles from 6,532 international scientists who attracted more than 100 citations in 2019 and self-identified with at least one of 10 common psychological disciplines (psychoanalysis; clinical psychology; (cognitive) neuroscience; developmental psychology; educational psychology; experimental psychology; biological psychology/psychophysiology; mathematical psychology/psychometrics; social psychology; personality psychology). Results indicated that almost half of all psychologists self-identified with either social psychology or cognitive neuroscience. There were 487 topics that were endorsed at least five times, ranging from highly discipline-specific topics to more integrative ones, such as emotion and personality. We also factor-analyzed frequencies of topical endorsement across disciplines and found two factors, which we interpreted as reflecting correlational and experimental research traditions (with social psychology being the largest discipline within the former tradition and cognitive neuroscience being the largest discipline within the latter tradition). Differences in productivity and impact were also found, with researchers identifying with psychometrics being the most productive and researchers identifying with personality psychology, cognitive neuroscience, and multidisciplinary psychology as the most impactful in terms of citation increases per additional output. Recommendations for promoting cross-fertilization across psychological disciplines are formulated.
    DOI:  https://doi.org/10.1371/journal.pone.0296421
  52. JMIR Mhealth Uhealth. 2024 Jan 05. 12 e48716
       BACKGROUND: Anticoagulation management can effectively prevent complications in patients undergoing cardiac valve replacement (CVR). The emergence of eHealth tools provides new prospects for the management of long-term anticoagulants. However, there is no comprehensive summary of the application of eHealth tools in anticoagulation management after CVR.
    OBJECTIVE: Our objective is to clarify the current state, trends, benefits, and challenges of using eHealth tools in the anticoagulation management of patients after CVR and provide future directions and recommendations for development in this field.
    METHODS: This scoping review follows the 5-step framework developed by Arksey and O'Malley. We searched 5 databases such as PubMed, MEDLINE, Web of Science, CINAHL, and Embase using keywords such as "eHealth," "anticoagulation," and "valve replacement." We included papers on the practical application of eHealth tools and excluded papers describing the underlying mechanisms for developing eHealth tools. The search time ranged from the database inception to March 1, 2023. The study findings were reported according to the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews). Additionally, VOSviewer (version 1.6.18) was used to construct visualization maps of countries, institutions, authors, and keywords to investigate the internal relations of included literature and to explore research hotspots and frontiers.
    RESULTS: This study included 25 studies that fulfilled the criteria. There were 27,050 participants in total, with the sample size of the included studies ranging from 49 to 13,219. The eHealth tools mainly include computer-based support systems, electronic health records, telemedicine platforms, and mobile apps. Compared to traditional anticoagulation management, eHealth tools can improve time in therapeutic range and life satisfaction. However, there is no significant impact observed in terms of economic benefits and anticoagulation-related complications. Bibliometric analysis suggests the potential for increased collaboration and opportunities among countries and academic institutions. Italy had the widest cooperative relationships. Machine learning and artificial intelligence are the popular research directions in anticoagulation management.
    CONCLUSIONS: eHealth tools exhibit promise for clinical applications in anticoagulation management after CVR, with the potential to enhance postoperative rehabilitation. Further high-quality research is needed to explore the economic benefits of eHealth tools in long-term anticoagulant therapy and the potential to reduce the occurrence of adverse events.
    Keywords:  anticoagulation management; bibliometrics analysis; cardiac valve replacement; eHealth tool; rehabilitation; scoping review
    DOI:  https://doi.org/10.2196/48716
  53. Account Res. 2024 Jan 02. 1-21
      Despite the increasing prominence of research collaboration, a growing number of studies have confirmed that increasing team size can have limited performance benefits. However, the mechanism of this phenomenon has yet to be established. This study, therefore, quantified responsibility diffusion based on author contribution information and explored its mediating role in the relationship between collaboration size and citation impact (citation count in a four-year window). The results show the following: (1) An inverted U-shaped relationship exists between team size and citation count. (2) Responsibility diffusion plays a partial mediating role between team size and citation count. (3) As team size increases, the degree of responsibility diffusion increases. Lastly, (4) responsibility diffusion has an inverted U-shaped curvilinear relationship with citation count (e.g., a moderate degree of responsibility diffusion has the highest impact). These findings offer a new understanding of the mechanism by which collaboration size influences research performance. This study also has practical implications for solving research collaboration dilemmas based on a group-cognition perspective.
    Keywords:  Scientific collaboration; accountability; citation impact; responsibility diffusion; team size
    DOI:  https://doi.org/10.1080/08989621.2023.2300255
  54. PLoS One. 2024 ;19(1): e0296323
      In the present study, we analyzed a large corpus of English-language online media articles covering genome-wide association studies (GWAS), exemplifying the use of computational methods to study science communication in biological sciences. We analyzed trends in media coverage, readability, themes, and mentions of ethical and social issues, in over 5,000 websites published from 2005 to 2018 from 3,555 GWAS publications on 1,943 different traits, identified via GWAS Catalog using a text-mining approach to inform the discussion about genetic literacy and media coverage. We found that 22.9% of GWAS papers received media attention but most were described in language too complex to be understood by the public. Ethical issues are rarely mentioned and mentions of translation are increasing over time. We predicted media attention based on year of publication, number of genetic associations identified, study sample size, and journal impact factor, using a regression model (r2 = 38.7%). We found that chronotype, educational attainment, alcohol and coffee consumption, sexual orientation, tanning, and hair color received substantially more attention than predicted by the regression model. We also evaluated the prevalence of the clickbait "one gene, one disease" headlines (e.g., "Scientists Say They've Found Gene That Causes Breast Cancer") and found that it is declining. In sum, online media coverage of GWAS should be more accessible, introduce more modern genetics terms, and when appropriate, ELSI should be mentioned. Science communication research can benefit from big data and text-mining techniques which allow us to study trends and changes in coverage trends across thousands of media outlets. Results can be explored interactively in a website we have built for this manuscript: https://jjmorosoli.shinyapps.io/newas/.
    DOI:  https://doi.org/10.1371/journal.pone.0296323