bims-evares Biomed News
on Evaluation of research
Issue of 2024–03–03
seventy papers selected by
Thomas Krichel, Open Library Society
  1. Global research hotspots and trends on robotic surgery in obstetrics and gynecology: a bibliometric analysis based on VOSviewer.
  2. Global trends in neonatal MRI brain neuroimaging research over the last decade: a bibliometric analysis.
  3. Variations in Citations Across Databases: Implications for Journal Impact Factors.
  4. Current patterns and trends of microplastic pollution in the marine environment: A bibliometric analysis.
  5. Bibliometric analysis of the 3-year trends (2018-2021) in literature on artificial intelligence in ophthalmology and vision sciences.
  6. Bibliometric analysis and review of mine ventilation literature published between 2010 and 2023.
  7. Extracellular vesicles in the treatment of oxidative stress injury: global research status and trends.
  8. Research hotspots and frontiers of alcohol and epilepsy: A bibliometric analysis.
  9. A bibliometric analysis of literatures on uterine leiomyosarcoma in the last 20 years.
  10. Research progress of mitochondria in chronic obstructive pulmonary disease: a bibliometric analysis based on the Web of Science Core Collection.
  11. Ultrasonography in the intensive care unit: a bibliometrics analysis.
  12. Visual and bibliometric analysis of chronic rhinosinusitis and nasal polyps.
  13. Psychological capital research in HEIs: Bibliometric analysis of current and future trends.
  14. Knowledge mapping of anaplastic thyroid cancer treatments: a bibliometric analysis (2000-2023).
  15. Mapping trends and hotspots regarding the use of telenursing for elderly individuals with chronic diseases: A bibliometric analysis.
  16. Over twenty years of pedagogical research from Nurse Education in Practice: A bibliometric analysis from 2001 to 2023.
  17. Bibliometric analysis of machine learning trends and hotspots in arthroplasty literature over 31 years.
  18. Bibliometric analysis of intestinal microbiota and lung diseases.
  19. Research trends between diabetes mellitus and bariatric surgery researches: Bibliometric analysis and visualization from 1998 to 2023.
  20. Bibliometric analysis of antimalarial drug resistance.
  21. Mapping the intellectual structure of the research of omalizumab in chronic spontaneous urticaria: A bibliometric analysis.
  22. Global research on RNA vaccines for COVID-19 from 2019 to 2023: a bibliometric analysis.
  23. P2X7 receptors: a bibliometric review from 2002 to 2023.
  24. Bibliometric analysis of interspinous device in treatment of lumbar degenerative diseases.
  25. Revealing Academic Evolution and Frontier Pattern in the Field of Uveitis Using Bibliometric Analysis, Natural Language Processing, and Machine Learning.
  26. The evolution of smart hotels: A bibliometric review of the past, present and future trends.
  27. Bibliometric Indices As Indicators of Research Output: Analyzing Anesthesiologists as a Paradigm for Surgical Disciplines.
  28. The progress report of the Journal of Orthopaedics.
  29. Trends in gut-heart axis and heart failure research (1993-2023): A bibliometric and visual analysis.
  30. School refusal: mapping the literature by bibliometric analysis.
  31. The Top 100 Classical and Contemporary Papers on Elbow Surgery: A Trend Analysis of Elbow Surgery Literature.
  32. Mapping the Evolution of Clinical Trials on Drug-Resistant Tuberculosis: A Bibliometric Overview (1965-2023).
  33. Clinical Application of MRI in Coronavirus Disease 2019: A Bibliometric Analysis.
  34. A bibliometric review study of Michael Burawoy.
  35. Revolutionizing vascular imaging: trends and future directions of 4D flow MRI based on a 20-year bibliometric analysis.
  36. A bibliometric analysis of autism spectrum disorder signaling pathways research in the past decade.
  37. Top-50 cited articles on cysticercosis and neurocysticercosis.
  38. Current trends and future directions of global research on wastewater to energy: a bibliometric analysis and review.
  39. Visual analysis of the research literature on extracorporeal membrane oxygenation-assisted support for respiratory failure based on CiteSpace and VOSviewer: a 20-year study.
  40. Global research trends and prospects of cellular metabolism in colorectal cancer.
  41. Immune regulation and the tumor microenvironment in anti-PD-1/PDL-1 and anti-CTLA-4 therapies for cancer immune evasion: A bibliometric analysis.
  42. Preresidency research output among US neurological surgery residents.
  43. Research productivity and gender of research award recipients in international ophthalmology societies.
  44. The impact of Twitter/X promotion on visibility of research articles: Results of the #TweetTheJournal study.
  45. Using generative artificial intelligence in bibliometric analysis: 10 years of research trends from the European Resuscitation Congresses.
  46. Progress of evapotranspiration research based on VOSviewer: A review.
  47. A systematic evidence map and bibliometric analysis of the behavioural impacts of pesticide exposure on zebrafish.
  48. Exploring the topic structure and abuse trends of new psychoactive Substance since the 21st century from a bibliometric perspective.
  49. Academic accomplishments of Black neurosurgeons in the United States.
  50. [Review and prospect of traditional Chinese medicine in treatment of trauma based on bibliometrics].
  51. Trends in Stroke-Related Journals: Examination of Publication Patterns Using Topic Modeling.
  52. An Analysis of Medical Student PubMed-Indexed Research Productivity and Factors Associated With Matching at Top-Ranked Ophthalmology Residency Programs.
  53. The state of diversity among consultant neurologists in the United Kingdom.
  54. Pediatric hidradenitis suppurativa publication trends: 2012 to 2022.
  55. Analysis of dementia research trends in nursing using text mining approach.
  56. Clinical Research Fellowship Fosters Mentorship, Teamwork, and Productivity: Our 11-Year Experience With a Craniofacial Research Fellowship.
  57. Current and future of immunotherapy for thyroid cancer based on bibliometrics and clinical trials.
  58. What do we know about plastic pollution in Brazilian aquatic ecosystems?
  59. Grant funding among underrepresented minority and women urologists at academic institutions.
  60. An Overview of Physical Activity Research Evolution in Africa: The Global Observatory for Physical Activity-GoPA!
  61. Sex and gender publications in brain health: a mapping review of the Asia-Pacific region.
  62. A brief review and scientometric analysis on ensemble learning methods for handling COVID-19.
  63. Are our actions matching our words? A review of trainee ethnic and gender diversity in orthopaedic surgery.
  64. Developments and Trends of Nanotechnology Application in Sepsis: A Comprehensive Review Based on Knowledge Visualization Analysis.
  65. Informing nursing policy: An exploration of digital health research by nurses in England.
  66. The Influence of Human Connections and Collaboration on Research Grant Success at Various Career Stages: Regression Analysis.
  67. A scientometric analysis of oral cancer research in South/Southeast Asia and China in oral diseases.
  68. The promise of nanofluids: A bibliometric journey through advanced heat transfer fluids in heat exchanger tubes.
  69. What factors are associated with the research productivity of primary care researchers in Canada? A qualitative study.
  70. Bibliometric analysis of Advanced Oxidation Processes studies with a focus on Life Cycle Assessment and Costs.
  1. Front Surg. 2024 ;11 1308489
    Global research hotspots and trends on robotic surgery in obstetrics and gynecology: a bibliometric analysis based on VOSviewer.
    Peichen Xiao, Lu Li, Jinfeng Qu, Guangxin Wang.
       Objective: Over the last two decades, the quantity of papers published in relation to robotic surgery in obstetrics and gynecology has continued to grow globally. However, no bibliometric analysis based on VOSviewer has been performed to evaluate the past and present of global research in the field. In this study, we aimed to analyze the bibliometric characteristics of papers on robotic surgery in obstetrics and gynecology to reveal research hotspots and trends in this field.
    Methods: The Web of Science Core Collection was searched for scientific papers on robotic surgery in obstetrics and gynecology published between January 1, 1998 and December 31, 2023. Bibliometric metadata of each selected paper was extracted for analysis. The results were visualized by VOSviewer (version 1.6.18).
    Results: A total of 1,430 papers met the inclusion criteria. The United States had the highest total link strengths and contributed the most papers (n = 793). The Mayo Clinic produced the largest number of papers (n = 85), and Professor Pedro T Ramirez contributed the most papers (n = 36). The number of citations ranged from 0 to 295 with a total sum of 29,103. The Journal of Minimally Invasive Gynecology published the most relevant papers (n = 252). Keywords were classified into six clusters based on co-occurrence data, of which cluster 1, cluster 4 and cluster 6 had more main keywords with the largest average publication year.
    Conclusions: This is the first VOSviewer-based bibliometric analysis of robotic surgery research in obstetrics and gynecology. The United States was the leading country, and the Journal of Minimally Invasive Gynecology was the most productive journal in the field. Scientists and institutions from around the world should push their boundaries to bring about deep collaboration. The main research topic has always been the use of robotic surgery in the treatment of gynecologic malignancies. More randomized controlled trials need to be conducted to compare surgical outcomes of robotic surgery with other surgical approaches. Robotic sacrocolpopexy for pelvic organ prolapse has become a new research hotspot, and robotic surgery for sentinel lymph node detection in gynecologic malignancies are more potential directions for future research.
    Keywords:  VOSviewer; Web of Science; bibliometric analysis; obstetrics and gynecology; robotic surgery
    DOI:  https://doi.org/10.3389/fsurg.2024.1308489
  2. Quant Imaging Med Surg. 2024 Feb 01. 14(2): 1526-1540
    Global trends in neonatal MRI brain neuroimaging research over the last decade: a bibliometric analysis.
    Shengfang Xu, Jinlong Zhang, Songhong Yue, Jifang Qian, Dalin Zhu, Yankai Dong, Guangyao Liu, Jing Zhang.
       Background: Neuroimaging plays a central role in the evaluation, treatment, and prognosis of neonates. In recent years, the exploration of the developing brain has been a major focus of research for researchers and clinicians. In this study, we conducted bibliometric and visualization analyses of the related studies in the field of neonatal magnetic resonance imaging (MRI) brain neuroimaging from the past 10 years, and summarized its research status, hotspots, and frontier development trends.
    Methods: The Web of Science core collection database was used as the literature source from which to retrieve the relevant papers and reviews in the field of neonatal MRI brain neuroimaging published in the Science Citation Index-Expanded from 2013 to 2022. VOSviewer and CiteSpace were used to conduct bibliometric and visualization analyses of the annual publication volume, countries, institutions, journals, authors, co-cited literature, and the overall distribution of keywords.
    Results: We retrieved 3,568 papers and reviews published from 2013 to 2022. The number of publications increased during this period. The United States (US) and the United Kingdom were the largest contributors, with the US receiving the highest H-index and number of citations. The institutions that published the most were the University of London and Harvard University. The research mainly focused on cerebral cortex, brain tissue, brain structure network, artificial intelligence algorithm, automatic image segmentation, and premature infants.
    Conclusions: This study reveals the research status and hotspots of magnetic resonance imaging in the field of neonatal brain neuroimaging in the past decade, which helps researchers to better understand the research status, hotspots, and frontier development trends.
    Keywords:  Neonatal; bibliometrics; magnetic resonance imaging (MRI); neuroimaging; visualization analysis
    DOI:  https://doi.org/10.21037/qims-23-880
  3. Semin Ophthalmol. 2024 Feb 28. 1-4
    Variations in Citations Across Databases: Implications for Journal Impact Factors.
    Khaled Moustafa.
      The Journal Impact Factor (JIF) is a widely used metric for ranking journals based on the number of citations garnered by papers published over a specific timeframe. To assess the accuracy of JIF values, I compared citation counts for 30 of my own publications across six major bibliography databases: CrossRef, Web of Science, Publisher records, Google Scholar, PubMed and Scopus. The analysis revealed noteworthy variations in citation counts, ranging from 10% to over 50% between the lowest and highest citation counts. Google Scholar records the highest citation numbers, while PubMed reported the lowest. Notably, Web of Science, whose citation data are used in JIF calculations, tend to underestimate citation counts compared to other databases. These observations raise concerns about the accuracy of JIF calculation based on Web of Science's citation data. The real JIF values for most journals would differ from those annually reported by Clarivate's journal citation reports (JCR). These citation discrepancies underscore the importance of comprehensive data collection and the necessity to include additional citation sources. Not because a paper is cited in one journal rather than another should it have a less or more citation weight. Ultimately, one citation remains one citation, regardless of its origin. Clarivate Analytics may thus need to consider integrating all citation sources for more accurate JIF values. Alternatively, Google Scholar could potentially develop its own journal or citation impact based on its extensive journal citation records. However, while making adjustments to how the Journal Impact Factor is calculated can make it more mathematically precise, it doesn't address the fundamental biases built into the metric. Even with refinements, the Journal Impact Factor will remain skewed due to how it's defined and used.
    Keywords:  Journal impact factor (JIF); citaion index; citation analysis; citation bias; citation discrepancy; clarivate analytics; google scholar: journal ranking; highly cited authors; highly cited journal; journal citation report
    DOI:  https://doi.org/10.1080/08820538.2024.2322428
  4. Environ Sci Pollut Res Int. 2024 Feb 28.
    Current patterns and trends of microplastic pollution in the marine environment: A bibliometric analysis.
    Manoranjan Mishra, Desul Sudarsan, Celso Augusto Guimarães Santos, Richarde Marques da Silva, Santosh Kumar Beja, Suman Paul, Pragati Bhanja, Murtyunjya Sethy.
      Microplastics are pervasive in the natural environment and pose a growing concern for global health. Plastic waste in marine environments has emerged as a global issue, threatening not only marine biota but also human health due to its implications for the food chain. This study aims to discern the patterns and trends of research, specifically on Marine Microplastic Pollution (MMP), based on a bibliometric analysis of scientific publications from 2011 to 2022. The methodology utilized in this study comprises three stages: (a) creating a bibliographical dataset from Scopus by Elsevier and the Web of Science Core Collection by Clarivate Analytics, (b) analyzing current research (trends and patterns) using bibliometric analysis through Biblioshiny tool, and (c) examining themes and subthemes in MMP research (wastewater treatment, plastic ingestion, the Mediterranean Sea, microplastics pollution, microplastics in freshwater, microplastic ingestion, plastic pollution, and microplastic pollution in the marine environment). The findings reveal that during the studied period, the number of MMP publications amounted to 1377 articles, with an average citation per publication of 59.23 and a total citation count of 81,553. The most cited article was published in 2011, and since then, the number of publications on this topic has been increasing steadily. The author count stood at 5478, with 22 trending topics identified from the 1377 published titles. Between 2019 and 2022, the countries contributing most to the publication of MMP articles were China, the United States of America (USA), and the United Kingdom (UK). However, a noticeable shift in the origin of author countries was observed in the 2019-2022 timeframe, transitioning from a dominance by the USA and the UK to a predominance by China. In 2019, there was a substantial increase in the volume of publications addressing the topic of microplastics. The results show that the most prevalent themes and subthemes pertained to MMP in the Mediterranean Sea. The journals with the highest number of MMP articles published were the Marine Pollution Bulletin (253 articles) and Science of the Total Environment (190 articles). The analysis concludes that research on MMP remains prominent and appears to be increasing each year.
    Keywords:  Environmental degradation; Marine pollution; Oceanic ecosystem; Tendencies
    DOI:  https://doi.org/10.1007/s11356-024-32511-x
  5. BMJ Health Care Inform. 2024 Feb 28. pii: e100780. [Epub ahead of print]31(1):
    Bibliometric analysis of the 3-year trends (2018-2021) in literature on artificial intelligence in ophthalmology and vision sciences.
    Hayley Monson, Jeffrey Demaine, Adrianna Perryman, Tina Felfeli.
       OBJECTIVES: The objective of this analysis is to present a current view of the field of ophthalmology and vision research and artificial intelligence (AI) from topical and geographical perspectives. This will clarify the direction of the field in the future and aid clinicians in adapting to new technological developments.
    METHODS: A comprehensive search of four different databases was conducted. Statistical and bibliometric analysis were done to characterise the literature. Softwares used included the R Studio bibliometrix package, and VOSviewer.
    RESULTS: A total of 3939 articles were included in the final bibliometric analysis. Diabetic retinopathy (391, 6% of the top 100 keywords) was the most frequently occurring indexed keyword by a large margin. The highest impact literature was produced by the least populated countries and in those countries who collaborate internationally. This was confirmed via a hypothesis test where no correlation was found between gross number of published articles and average number of citations (p value=0.866, r=0.038), while graphing ratio of international collaboration against average citations produced a positive correlation (r=0.283). Majority of publications were found to be concentrated in journals specialising in vision and computer science, with this category of journals having the highest number of publications per journal (18.00 publications/journal), though they represented a small proportion of the total journals (<1%).
    CONCLUSION: This study provides a unique characterisation of the literature at the intersection of AI and ophthalmology and presents correlations between article impact and geography, in addition to summarising popular research topics.
    Keywords:  Artificial intelligence; BMJ Health Informatics; Data Visualization; Informatics
    DOI:  https://doi.org/10.1136/bmjhci-2023-100780
  6. Heliyon. 2024 Feb 29. 10(4): e26133
    Bibliometric analysis and review of mine ventilation literature published between 2010 and 2023.
    Yan Xue, Jinmiao Wang, Jun Xiao.
      To provide scholars with a quick understanding of the current status, research hotspots, and future trends in the field of mine ventilation, this paper conducted a visualized bibliometric analysis and a comprehensive review of mine ventilation-related literature from 2010 to 2023 using CiteSpace. A thorough analysis of the publication time, co-authorship, co-citation, keywords, and research topics of the literature was carried out. Based on this, through systematic literature reading and summarization, research topics in the field of mine ventilation were organized, analyzed, and classified. The results indicate that mine ventilation research from 2010 to 2023 went through three stages: stable development, slow growth, and rapid ascent. Nie Wen and China Univ Min & Technol were the most prolific authors and institutions in the field of mine ventilation. China had the highest number of publications during 2010-2023, while Canada and Poland exhibited the highest centrality, signifying their key roles in the mine ventilation domain. Deep mine ventilation and intelligent mine ventilation emerged as research hotspots and mainstream trends in the future. The analysis of multiple hazard coupling studies represents a research direction that mine ventilation needs to develop. Numerical simulation techniques should not be limited to static analysis, as dynamic simulation is a focal area of interest.
    Keywords:  Bibliometric analysis; CiteSpace; Mine ventilation; Visualization analysis
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e26133
  7. Front Mol Biosci. 2023 ;10 1273113
    Extracellular vesicles in the treatment of oxidative stress injury: global research status and trends.
    Wenwen Zhang, Bin Gan, Tingyu Wang, Xiangjie Yang, Yuanye Xue, Yuanqing Zhong, Xintong He, Xinsheng Peng, Yanfang Zhou, Xiaoyan Cheng.
      Objective: The aim of this study was to conduct a bibliometric analysis of the literature on "Extracellular Vesicles in the Treatment of Oxidative Stress Injury" and to reveal its current status, hot spots and trends. Methods: The relevant literature was obtained from the Web of Science Core Collection (WoSCC) on 29 April 2023. We performed clustering and partnership analysis of authors, institutions, countries, references and keywords in the literature through CiteSpace software and the bibliometric online analysis platform and mapped the relevant knowledge maps. Results: A total of 1,321 relevant publications were included in the bibliometric analysis, with the number of publications in this field increasing year by year. These included 944 "articles" and 377 "reviews". The maximum number of publications published in China is 512, and the maximum number of highly cited publications published in the United States is 20. Based on CiteSpace, the country collaboration network map shows close and stable collaboration among high-productivity countries. Based on WoSCC, there are 1706 relevant research institutions and 119 highly cited elite institutions, among which Kaohsing Chang Gung Men Hosp has the most extensive influence. Studies related to "Extracellular Vesicles in the Treatment of Oxidative Stress Injury" have been published in 548 journals. The keywords of the publications show the main research areas and breakthroughs. Based on WoSCC, the keywords of the research area "Extracellular Vesicles in the Treatment of Oxidative Stress Injury" were found to be as follows: exosome(s), extracellular vesicle(s), oxidative stress, inflammation, mesenchymal stem cells, apoptosis, microRNA (miRNA), mitochondria, biomarker, autophagy, angiogenesis and Alzheimer's disease. Analysis showed that "mesenchymal stem cells", "microRNA", "autophagy", "histology" and "therapeutic" emerged as highly explosive keywords. Conclusion: This study is the first to use visual software and data mining to assess the literature in the field of "Extracellular Vesicles in the Treatment of Oxidative Stress Injury". The research history, research status and direction in this field provide a theoretical basis for its scientific research.
    Keywords:  Exosomes; bibliometrics; cluster analysis; extracellular vesicles; oxidative Stress
    DOI:  https://doi.org/10.3389/fmolb.2023.1273113
  8. Neuropsychopharmacol Rep. 2024 Mar 01.
    Research hotspots and frontiers of alcohol and epilepsy: A bibliometric analysis.
    Wenhui Liu, Huan Li, Simei Lin.
       PURPOSE: Alcohol is implicated in epileptogenesis and seizures attack. An increasing number of studies about alcohol and epilepsy have been published. We aimed to assess research trends and hot spots in the field of alcohol and epilepsy.
    PATIENTS AND METHODS: Literature concerning alcohol and epilepsy was systemically searched through the Web of Science database. Collaborative maps were quantitatively analyzed by using the VOSviewer and CiteSpace tools.
    RESULTS: A total of 1578 papers about the field of alcohol and epilepsy were taken into analysis, which was written by 6840 authors from 2153 institutions in 85 countries, published in 676 journals, and cited 79 667 references from 10 750 journals. The United States was the leading country and had close ties with others. The University of Toronto was the most productive institution. Alcoholism-clinical and experimental research was the fastest-growing journal. Richard J. Bodnar was the author contributing the most literature. Analysis of keywords showed epilepsy, alcohol, seizures, alcohol withdrawal, and management were common themes.
    CONCLUSION: The presented study conducted the first bibliometric analysis of the field of alcohol and epilepsy, which will provide insights into the latest progress, evolution paths, frontier research hot spots, and future research trends in the field.
    Keywords:  CiteSpace; VOSviewer; Web of Science; alcohol; bibliometric analysis; epilepsy
    DOI:  https://doi.org/10.1002/npr2.12421
  9. Front Oncol. 2024 ;14 1343533
    A bibliometric analysis of literatures on uterine leiomyosarcoma in the last 20 years.
    Jinhua Huang, Yu Chen, Ziyin Li, Mimi Chen, Dingwen Huang, Peixin Zhu, Xintong Han, Yi Zheng, Xiaochun Chen, Zhiying Yu.
       Background: Uterine leiomyosarcoma(uLMS) is a rare malignant tumor with low clinical specificity and poor prognosis.There are many studies related to uLMS, however, there is still a lack of metrological analyses with generalization. This study provides a bibliometric study of uLMS.
    Methods and materials: We chose the Web of Science (WoS) as our main database due to its extensive interdisciplinary coverage. We specifically focused on the literature from the last 20 years to ensure relevance and practicality. By utilizing the WOS core dataset and leveraging the R package "bibliometric version 4.1.0" and Citespace, we performed a comprehensive bibliometric analysis. This allowed us to pinpoint research hotspots and create visual representations, resulting in the retrieval of 2489 pertinent articles.
    Results: This literature review covers 2489 articles on uterine leiomyosarcoma (uLMS) from the past 20 years. Key findings include an average annual publication rate of 8.75, with a 6.07% yearly growth rate and an average citation count of 17.22. Core+Zone 2 sources contributed 1079 articles and 207 reviews, displaying a 4.98% annual growth rate. The analysis identified top journals, influential authors, and core sources, such as the prevalence of publications from the United States and the dominance of GYNECOLOGIC ONCOLOGY and HENSLEY ML. Bradford's Law and Lotka's Law highlighted core sources and author productivity, respectively. Thematic mapping and factorial analysis revealed research clusters, including etiology, diagnosis, treatment advancements, and surgical approaches, with prominent themes such as gemcitabine and docetaxel. Overall, this comprehensive analysis provides insights into uLMS literature trends and influential factors.
    Conclusion: This thorough bibliometric analysis, in its whole, illuminates the field's guiding principles while also revealing the subtle patterns within the uLMS literature. The knowledge gained here contributes to the current discussion in uLMS and related scientific fields and provides a solid basis for future research paths.
    Keywords:  bibliometric analysis; gynecologic malignance; top relavant keywords; trend topic; uterine leiomyosarcoma
    DOI:  https://doi.org/10.3389/fonc.2024.1343533
  10. J Thorac Dis. 2024 Jan 30. 16(1): 215-230
    Research progress of mitochondria in chronic obstructive pulmonary disease: a bibliometric analysis based on the Web of Science Core Collection.
    Naer An, Jing An, Tingting Zeng, Shuyan Wang, Ping Li, Xueru Hu, Yongchun Shen, Lian Liu, Fuqiang Wen.
       Background: Due to its high morbidity and mortality, chronic obstructive pulmonary disease (COPD) has become a major global healthcare issue. Although there is abundant research regarding COPD, a bibliometric analysis of the literature related to mitochondria and COPD is lacking. Thus this study aimed to summarize the research status, research direction, and research hotspots of the published articles concerning COPD and mitochondria.
    Methods: A literature search for included publications related to COPD and mitochondria was carried out on the Web of Science Core Collection from the date of database establishment to December 15, 2022. A subsequent bibliometric and visual analysis of the included publications was conducted via Microsoft Excel, R software, CiteSpace, and VOSviewer.
    Results: A total of 227 published articles on COPD and mitochondria from 139 journals were included. Over the study period, the annual publication number and citation frequency in this field both showed a trend of continuous growth. The United States had the highest centrality and was the most productive country. The frequently occurring keywords were "oxidative stress", "obstructive pulmonary disease", "dysfunction", "mitochondria", "inflammation", and "cigarette smoke", among others. Recent research hotspots included autophagy, model, mitochondria, health, and extracellular vesicles (EVs). Despite an abundance and variety of research, there is still relatively little academic communications between scholars and institutions.
    Conclusions: This bibliometric study can help researchers gain a quick overview of the research into mitochondria and COPD and thus inform novel ideas and directions for future research in this field.
    Keywords:  CiteSpace; Mitochondria; VOSviewer; bibliometric analysis; chronic obstructive pulmonary disease (COPD)
    DOI:  https://doi.org/10.21037/jtd-23-777
  11. J Thorac Dis. 2024 Jan 30. 16(1): 623-631
    Ultrasonography in the intensive care unit: a bibliometrics analysis.
    Xijuan Peng, Tao Luo, Linong Yao, Rivka Kessner, Wei Wu, Luigi Bonavina, Samy Lachkar.
       Background: Ultrasonography is widely used in critical care practice. The status of related studies remains unclear. The purpose of this study is to analyze current literature investigating the use of ultrasound in critical care units by using bibliometric analysis.
    Methods: The Science Citation Index Expanded (SCI-E) database was used for data retrieval. The search formula for literature retrieval was "ultrasound" OR "ultrasonography" AND "intensive care unit" OR "critical care unit" OR "intensive care" OR "critical care". The bibliometric software package of R software was used to analyze the results. Information of related literatures were analyzed.
    Results: Finally, 3,715 articles were included. The number of published articles and the number of references increased annually. The research fields included medical imaging, critical care medicine, cardiology, etc. The United States has published more documents in this field than other countries and has shown the highest rate of cooperation with other countries. Among the top 10 research institutions with the largest number of publications, 5 are from France and 3 are from the United States. There are many authors from China in the top 10 published studies. Among the top 10 journals with the largest number of published articles, 5 journals are top journals in the field of critical care medicine. Among the top 10 keywords, there are 5 of ultrasound specialty and 2 of critical care medicine.
    Conclusions: Researches on the use of ultrasound in critical care units are mainly concentrated in several developed countries in Europe and the United States. Chinese research institutions should perform more studies in this field and increase cooperation with institutions from other countries.
    Keywords:  Critical care; bibliometric analysis; cooperation; ultrasonography; ultrasound
    DOI:  https://doi.org/10.21037/jtd-23-1190
  12. J Allergy Clin Immunol Glob. 2024 May;3(2): 100211
    Visual and bibliometric analysis of chronic rhinosinusitis and nasal polyps.
    Zhichen Liu, Yuxu Yao, Huanxia Xie, Aina Zhou, Yuhui Fan, Jisheng Liu, Qingqing Jiao.
       Background: Chronic rhinosinusitis (CRS) is a heterogeneous disease characterized by persistent sinonasal inflammation and sinus microbiome dysbiosis. Nasal polyps (NPs) are one of the main manifestations that cause diverse clinical symptoms of CRS.
    Objective: We sought to conduct a bibliometric and visual analysis of articles on CRS and NPs published between 2003 and 2022 to provide researchers with the current state of research and potential directions.
    Methods: We searched relevant articles from 2003 to 2022 in the Web of Science database. VOSviewer and the Bibliometrix R package were used to perform the bibliometric analysis.
    Results: A total of 3907 publications were retrieved. The United States made the highest contributions to global research, followed by China. Northwestern University had the most publications. The most published author was C. Bachert, followed by R. P. Schleimer and R. J. Schlosser. The authors with the most co-citations were C. Bachert, W. J. Fokkens, and P. Gevaert. Moreover, the journal with the most publications was the International Forum of Allergy & Rhinology, and the Journal of Allergy and Clinical Immunology was the most cited. "Covid-19," "biologics," and "type 2 inflammation" were the top current research hotspots.
    Conclusions: The United States and Northwestern University were the leading country and institution in researching CRS and NPs. C. Bachert was the most influential expert. The International Forum of Allergy & Rhinology and the Journal of Allergy and Clinical Immunology were leading journals. "Covid-19," "biologics," and "type 2 inflammation" were the trending topics.
    Keywords:  Bibliometrics; Bibliometrix; VOSviewer; chronic rhinosinusitis; nasal polyps
    DOI:  https://doi.org/10.1016/j.jacig.2024.100211
  13. Heliyon. 2024 Feb 29. 10(4): e26607
    Psychological capital research in HEIs: Bibliometric analysis of current and future trends.
    Li Zhang, Walton Wider, Muhammad Ashraf Fauzi, Leilei Jiang, Jem Cloyd M Tanucan, Lester Naces Udang.
      This study presents a comprehensive bibliometric analysis of the literature on psychological capital (PsyCap) within higher education institutions (HEIs). Its main objective is to offer an encompassing perspective on this field's current state and potential developments. To achieve this, the study examines present research trends and predicts future directions using a bibliometric approach. A total of 412 journal articles were gathered from the Web of Science database. The analysis identifies influential publications, outlines the knowledge structure, and forecasts future trends through bibliographic coupling and co-word analyses. The bibliographic coupling revealed five distinct clusters, while the co-word analysis identified four clusters. Despite the growing significance of PsyCap research in HEIs, there remains a need for greater academic efforts to comprehend the research landscape fully. This paper provides valuable insights into the expanding area of PsyCap research within HEIs. In conclusion, the study sheds light on the extensive research conducted on PsyCap in the context of HEIs and offers insights into its potential for further growth.
    Keywords:  Bibliometric analysis; Higher education institutions; Mental health; Psychological capital; Web of science
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e26607
  14. Front Oncol. 2024 ;14 1330030
    Knowledge mapping of anaplastic thyroid cancer treatments: a bibliometric analysis (2000-2023).
    Shiqiang Liu, Xingmin Yan, Yalong Yang, Yun Xia, Panshi Zhang.
       Context: Anaplastic thyroid cancer (ATC) is a relatively rare and extensively malignant kind of thyroid carcinoma. The poor prognosis and high mortality rate of ATC can be attributed to its invasive features and undifferentiated phenotype. At present, there is a lack of efficacious therapeutic options. In light of the elevated fatality rate, it is vital to possess a comprehensive comprehension of the scientific terrain pertaining to ATC. To gather the perspectives of different researchers about the topic of ATC treatment, we did a bibliometric network analysis, which offers a comprehensive view of the scholarly literature.
    Methodology: A systematic search was conducted on the WoSCC database to identify publications pertaining to ATC treatment between the years 2000 and 2023. In this bibliometric investigation, the tools VOSviewers, CiteSpace, and the R package "bibliometrix" were employed to investigate the general attributes, developmental framework, and academic frontiers of the subject matter.
    Results: 1223 publications in total, written by 6937 scholars from 53 areas and 1402 institutions and published in 358 scholarly journals, were analyzed. There has been a gradual increase in the quantity of publications pertaining to ATC treatment. The United States and China emerged as the most prominent nations. The University of Texas MD Anderson Cancer Center and Memorial Sloan Kettering Cancer Counseling Center are prominent research institutions in highly productive countries. The journal Thyroid holds a prominent position within its discipline, being widely recognized as both the most popular and highly co-cited publication. According to the available data, Maria Cabanillas has authored the highest number of published articles, while RC Smallridge has received the highest number of co-citations. It turned out that the prevailing keywords encompassed expression, therapy, apoptosis, survival, activation, proliferation, metastasis, and other related terms. Immunotherapy, targeted therapy, and prognostic factors are the emerging research hotspots and trends.
    Conclusions: This paper presents a complete overview of research trends and advancements in the treatment of ATC using bibliometric analysis. The acquisition of information will offer vital insights for funding and potential creative strategies in researching the treatment of ATC, which indicates the research frontiers as well as prevalent directions in recent years.
    Keywords:  anaplastic thyroid cancer; bibliometric analysis; endocrine; thyroid cancer; treatment
    DOI:  https://doi.org/10.3389/fonc.2024.1330030
  15. Medicine (Baltimore). 2024 Mar 01. 103(9): e37313
    Mapping trends and hotspots regarding the use of telenursing for elderly individuals with chronic diseases: A bibliometric analysis.
    Yuan Yuan, Sican Wang, Chunhua Tao, Zhie Gu, Akio Kitayama, Kiyoko Yanagihara, Jingyan Liang.
       BACKGROUND: Telenursing is receiving extensive attention from scholars and medical staff. However, there are few studies on the knowledge structure of telenursing for elderly individuals with chronic diseases. This study aims to demonstrate current research status and development trend of telenursing for elderly individuals with chronic diseases through a visual analysis of CiteSpace, so as to provide a more comprehensive perspective for future researches.
    METHODS: Literature about telenursing for elderly patients with chronic diseases from 2002 to 2022 was retrieved from the Web of Science Core Collection using CiteSpace 6.1.R3.
    RESULTS: A total of 375 records were obtained. Annual publication and citation frequency gradually increased over the investigated period, reaching a peak in 2022. Journal of Telemedicine and Telecare was the most prolific and the most cited journal. The United States was the most productive country, the University of Melbourne was the most productive institution, and the author CHEN C ranked the highest in the number of publications. The most popular keywords were "care," "telemedicine," "management," "older adult," "chronic disease," "health," and "heart failure," which had a high frequency and centrality. The keywords "telehealth," "randomized controlled trail," "chronic obstructive pulmonary disease," "implementation" and "time" showed the strongest citation burst. The keywords were clustered to form 10 labels. The article published in 2010 by Chaudhry SI was cited the most. The top 3 cited journals were all special journal of telemedicine.
    CONCLUSION: This study revealed current research status and development trend of telenursing for elderly individuals with chronic diseases. The bibliometric analysis of telenursing expands the knowledge field of telemedicine and provides new insights into the management of elderly patients with chronic diseases.
    DOI:  https://doi.org/10.1097/MD.0000000000037313
  16. Nurse Educ Pract. 2024 Feb 15. pii: S1471-5953(24)00041-6. [Epub ahead of print]76 103912
    Over twenty years of pedagogical research from Nurse Education in Practice: A bibliometric analysis from 2001 to 2023.
    Siobhan O'Connor.
       AIM: To present a bibliometric overview of pedagogical research from Nurse Education in Practice from its inception in 2001 up until 2023.
    BACKGROUND: Bibliometric methods are useful in analysing and understanding the characteristics of scientific publications in a particular field and the influence of specific journals. However, no bibliometric analysis of a nurse education journal has been undertaken to date which would highlight important research trends in this area of nursing and midwifery.
    METHODS: A total of 2231 publications (articles and reviews only) from Nursing Education in Practice were retrieved from the Scopus database between 2001 and 2023. Several software applications including Microsoft Excel and VOSviewer were used to undertake bibliometric analysis on this dataset. Publication trends such as country analysis, author analysis, keywords analyses (cluster, content and trend analysis) were generated to help understand the volume and scope of pedagogical nursing and midwifery research in this journal.
    RESULTS: There has been a steady increase in pedagogical research from Nurse Education in Practice since its launch in 2001 up until 2018, with a dip in publications in 2022 most likely due to the impact of restrictions during the coronavirus pandemic. The most prolific institutions publishing in the journal are mainly from the United Kingdom, Australia and the United States, with over eighty countries represented demonstrating its global reach and impact. Nursing students, nursing education, simulation and learning are some of the most frequent author keywords.
    CONCLUSION: The diversity of pedagogies in nursing and midwifery education, clinical learning and supervision in practice environments, and competence and confidence when transitioning to practice are the most popular research areas in Nurse Education in Practice. This study informs nurse and midwife educators and scholars about the volume and scope of pedagogical research in nursing and midwifery. It also makes recommendations on how to improve aspects of scholarship in education and areas for future pedagogical research.
    Keywords:  Bibliometrics; International Collaboration; Learning; Nursing Education; Nursing Student; Pedagogy; Research; Teaching
    DOI:  https://doi.org/10.1016/j.nepr.2024.103912
  17. J Orthop. 2024 May;51 142-156
    Bibliometric analysis of machine learning trends and hotspots in arthroplasty literature over 31 years.
    Matthew P Corsi, Fong H Nham, Eliana Kassis, Mouhanad M El-Othmani.
       Background: Artificial intelligence has demonstrated utility in orthopedic research. Algorithmic models derived from machine learning have demonstrated adaptive learning with predictive application towards outcomes, leading to increased traction in the literature. This study aims to identify machine learning arthroplasty research trends and anticipate emerging key terms.
    Methods: Published literature focused on machine learning in arthroplasty from 1992 to 2023 was selected through the Web of Science Core Collection of Clarivate Analytics. Following that, bibliometric indicators were attained and brought in to perform an additional examination using Bibliometrix and VOSviewer to identify historical and present patterns within the literature.
    Results: A total of 235 documents were obtained through bibliometric sourcing based on machine learning applications within the arthroplasty literature. Thirty-four countries published articles on the topic, and the United States was demonstrated to be the largest global contributor. Four hundred-five institutions internationally contributed articles, with Harvard Medical School and the University of California system as the most relevant institutes, with 75 and 44 articles produced, respectively. Kwon YM was the most productive author, while Haeberle HS and Ramkumar PN were the most impactful based on h-index. The Thematic map and Co-occurrence visualization helped identify both major and niche themes present in the scientific databases.
    Conclusions: Machine learning in arthroplasty research continues to gain traction with a growing annual production rate and contributions from international authors and institutions. Institutions and authors based in the United States are the leading contributors to machine learning applications within arthroplasty research. This research discerns trends that have occurred, are presently ongoing, and are emerging within this field, aiming to inform future hotspot development.
    Keywords:  Artificial intelligence; Cocitation analysis; Hip and knee arthroplasty; Machine learning; Scientific literature
    DOI:  https://doi.org/10.1016/j.jor.2024.01.016
  18. Front Cell Infect Microbiol. 2024 ;14 1347110
    Bibliometric analysis of intestinal microbiota and lung diseases.
    Weiting Sun, Tong Zhou, Peng Ding, Liuxue Guo, Xiujuan Zhou, Kunlan Long.
       Background: Increasing evidence suggests a close association between the intestinal microbiome and the respiratory system, drawing attention to studying the gut-lung axis. This research employs bibliometric methods to conduct a visual analysis of literature in the field of intestinal microbiota and lung diseases over the past two decades. It offers scientific foundations for research directions and critical issues in this field.
    Methods: We retrieved all articles on intestinal microbiota and lung diseases from the SCI-Expanded of WoSCC on October 25, 2023. The analysis included original articles and reviews published in English from 2011 to 2023. We utilized Python, VOSviewer, and CiteSpace to analyze the retrieved data visually.
    Results: A total of 794 publications were analyzed. China ranked first in the number of publications, while the United States had the highest citations and H-index. Jian Wang was the most prolific author. Zhejiang University was the institution with the highest number of publications. Frontiers in Microbiology was the journal with the most publications. Author keywords appearing more than 100 times included "intestinal microbiota/microbiome", "microbiota/microbiome", and "gut-lung axis".
    Conclusion: The correlation and underlying mechanisms between intestinal microbiota and lung diseases, including asthma, COPD, lung cancer, and respiratory infections, remain hot topics in research. However, understanding the mechanisms involving the gut-lung axis is still in its infancy and requires further elucidation.
    Keywords:  Citespace; VOSviewer; bibliometric analysis; intestinal microbiota; lung
    DOI:  https://doi.org/10.3389/fcimb.2024.1347110
  19. Obes Rev. 2024 Feb 29. e13730
    Research trends between diabetes mellitus and bariatric surgery researches: Bibliometric analysis and visualization from 1998 to 2023.
    Kaisheng Yuan, Xu Zhang, Bing Wu, Ruiqi Zeng, Ruixiang Hu, Cunchuan Wang.
      This study conducted a bibliometric analysis using the Web of Science Core Collection (WOSCC) to explore the relationship between diabetes mellitus and bariatric surgery (BS) from January 1985 to August 2023. No publications were found between 1985 and 1998. However, from 1998 to 2023, a total of 9,496 English articles were identified, accumulating 291,289 citations (241,563 excluding self-citations) and achieving an H-Index of 197. Leading contributors to the field were the United States, China, and Italy. Noteworthy authors in this area of research included Philip R. Schauer, Wei-Jei Lee, and Carel W. le Roux. The major journals that featured this research were 'Obesity Surgery,' 'Diabetes Care,' and 'Surgery for Obesity and Related Diseases.' The most highly cited article focused on lifestyle, diabetes, and cardiovascular risks 10 years after BS, emphasizing the significant attention given to the nutritional, cardiac, and general internal medicine impacts of diabetes and BS. The increase in research output during the review period indicates a growing interest in the relationship between diabetes and BS, providing a valuable reference for future studies in this evolving field.
    Keywords:  bariatric surgery; bibliometric; data visualization; diabetes mellitus
    DOI:  https://doi.org/10.1111/obr.13730
  20. Front Cell Infect Microbiol. 2024 ;14 1270060
    Bibliometric analysis of antimalarial drug resistance.
    Jialu Zhang, Muhammad Shahbaz, Muhammad Ijaz, Huimin Zhang.
       Background: Malaria has always been a serious infectious disease prevalent in the world. Antimalarial drugs such as chloroquine and artemisinin have been the main compounds used to treat malaria. However, the massive use of this type of drugs accelerates the evolution and spread of malaria parasites, leading to the development of resistance. A large number of related data have been published by researchers in recent years. CiteSpace software has gained popularity among us researchers in recent years, because of its ability to help us obtain the core information we want in a mass of articles. In order to analyze the hotspots and develop trends in this field through visual analysis, this study used CiteSpace software to summarize the available data in the literature to provide insights.
    Method: Relevant literature was collected from the Web of Science Core Collection (WOSCC) from 1 January 2015 to 29 March 2023. CiteSpace software and Microsoft Excel were used to analyze and present the data, respectively.
    Results: A total of 2,561 literatures were retrieved and 2,559 literatures were included in the analysis after the removal of duplicates. An irrefutable witness of the ever-growing interest in the topic of antimalarial drug resistance could be expressed by the exponentially increased number of publications and related citations from 2015 to 2022, and its sustained growth trend by 2023. During the past 7 years, USA, Oxford University, and David A Fidock are the country, institution, and author with the most publications in this field of research, respectively. We focused on the references and keywords from literature and found that the research and development of new drugs is the newest hotspot in this field. A growing number of scientists are devoted to finding new antimalarial drugs.
    Conclusion: This study is the first visual metrological analysis of antimalarial drug resistance, using bibliometric methods. As a baseline information, it is important to analyze research output published globally on antimalarial drug resistance. In order to better understand the current research situation and future research plan agenda, such baseline data are needed accordingly.
    Keywords:  CiteSpace; anti-malarial; antimalarial drug; bibliometric analysis; resistance
    DOI:  https://doi.org/10.3389/fcimb.2024.1270060
  21. J Allergy Clin Immunol Glob. 2024 May;3(2): 100222
    Mapping the intellectual structure of the research of omalizumab in chronic spontaneous urticaria: A bibliometric analysis.
    Yuxu Yao, Zhichen Liu, Jiang Ji, Qingqing Jiao.
       Background: The guidelines for treating chronic spontaneous urticaria (CSU) recommend using the IgE-targeted biologic omalizumab in patients with antihistamine-refractory disease.
    Objective: Our aim was to present a bibliometric review of publications related to omalizumab and CSU over the past 2 decades.
    Methods: Relevant publications from 2003 to 2022 were extracted from the Science Citation Index-Expanded (SCI-EXPANDED) database in the Web of Science Core Collection database as of January 8, 2023. We utilized CiteSpace (version 6.1.R3), VOSviewer (version 1.6.18), and the R package (version 4.2.1) to analyze and visualize the data. The R package bibliometrix (version 4.2.1) was also used.
    Results: Between 2003 and 2022, a total of 566 articles on omalizumab and CSU were published. Since 2014, there has been a rapid increase in publication output. According to the collaboration network, the most influential country, institute, and scholar were the United States, Charité Universitätsmedizin Berlin, and Marcus Maurer, respectively. The study identified the Journal of Allergy and Clinical Immunology: In Practice as the most productive journal and the Journal of Allergy and Clinical Immunology as the most cocited journal. The analysis of key words revealed the presence of high-frequency terms such as angioedema, IgE, treatment, anti-IgE, asthma, and atopic dermatitis. Moreover, recent studies in this area have concentrated mainly on biomarkers, dupilumab, and coronavirus 2019 (COVID-19).
    Conclusion: There has been a growing interest in the use of omalizumab in CSU in recent years. The current trending topics in this research are the identification of biomarkers and the development of new mAbs for the treatment of CSU.
    Keywords:  Omalizumab; VOSviewer; bibliometric study; chronic spontaneous urticaria; knowledge map
    DOI:  https://doi.org/10.1016/j.jacig.2024.100222
  22. Front Immunol. 2024 ;15 1259788
    Global research on RNA vaccines for COVID-19 from 2019 to 2023: a bibliometric analysis.
    Ziyi Chen, Zhiliang Liu, Yali Feng, Aochen Shi, Liqing Wu, Yi Sang, Chenxi Li.
       Background: Since the global pandemic of COVID-19 has broken out, thousands of pieces of literature on COVID-19 RNA vaccines have been published in various journals. The overall measurement and analysis of RNA vaccines for COVID-19, with the help of sophisticated mathematical tools, could provide deep insights into global research performance and the collaborative architectural structure within the scientific community of COVID-19 mRNA vaccines. In this bibliometric analysis, we aim to determine the extent of the scientific output related to COVID-19 RNA vaccines between 2019 and 2023.
    Methods: We applied the Bibliometrix R package for comprehensive science mapping analysis of extensive bibliographic metadata retrieved from the Web of Science Core Collection database. On January 11th, 2024, the Web of Science database was searched for COVID-19 RNA vaccine-related publications using predetermined search keywords with specific restrictions. Bradford's law was applied to evaluate the core journals in this field. The data was analyzed with various bibliometric indicators using the Bibliometrix R package.
    Results: The final analysis included 2962 publications published between 2020 and 2023 while there is no related publication in 2019. The most productive year was 2022. The most relevant leading authors in terms of publications were Ugur Sahin and Pei-Yong, Shi, who had the highest total citations in this field. The core journals were Vaccines, Frontiers in Immunology, and Viruses-Basel. The most frequently used author's keywords were COVID-19, SARS-CoV-2, and vaccine. Recent COVID-19 RNA vaccine-related topics included mental health, COVID-19 vaccines in humans, people, and the pandemic. Harvard University was the top-ranked institution. The leading country in terms of publications, citations, corresponding author country, and international collaboration was the United States. The United States had the most robust collaboration with China.
    Conclusion: The research hotspots include COVID-19 vaccines and the pandemic in people. We identified international collaboration and research expenditure strongly associated with COVID-19 vaccine research productivity. Researchers' collaboration among developed countries should be extended to low-income countries to expand COVID-19 vaccine-related research and understanding.
    Keywords:  COVID-19; RNA vaccines; SARS-CoV-2; bibliometrics; web of science
    DOI:  https://doi.org/10.3389/fimmu.2024.1259788
  23. Purinergic Signal. 2024 Feb 29.
    P2X7 receptors: a bibliometric review from 2002 to 2023.
    Haiting Tang, Wei Wei, Yu Luo, Xiaoqing Lu, Jun Chen, Shenqiao Yang, Fei Wu, Haiyan Zhou, Wenbin Ma, Xin Yang.
      For many years, there has been ongoing research on the P2X7 receptor (P2X7R). A comprehensive, systematic, and objective evaluation of the scientific output and status of P2X7R will be instrumental in guiding future research directions. This study aims to present the status and trends of P2X7R research from 2002 to 2023. Publications related to P2X7R were retrieved from the Web of Science Core Collection database. Quantitative analysis and visualization tools were Microsoft Excel, VOSviewer, and CiteSpace software. The analysis content included publication trends, literature co-citation, and keywords. 3282 records were included in total, with the majority of papers published within the last 10 years. Based on literature co-citation and keyword analysis, neuroinflammation, neuropathic pain, gastrointestinal diseases, tumor microenvironment, rheumatoid arthritis, age-related macular degeneration, and P2X7R antagonists were considered to be the hotspots and frontiers of P2X7R research. Researchers will get a more intuitive understanding of the status and trends of P2X7R research from this study.
    Keywords:  Bibliometrics; CiteSpace; P2X7 receptors; VOSviewer; Visualization
    DOI:  https://doi.org/10.1007/s11302-024-09996-9
  24. Medicine (Baltimore). 2024 Mar 01. 103(9): e37351
    Bibliometric analysis of interspinous device in treatment of lumbar degenerative diseases.
    Yunxiang Hu, Rui Yang, Sanmao Liu, Hong Wang.
      In recent years, with the introduction of the concept of lumbar non-fusion, the interspinous device has emerged. The purpose of this study is to bibliometrically analyze the state, areas of interest, and emerging trends in the usage of interspinous devices for the treatment of lumbar degeneration disease, as well as related research fields. Between January 1, 2000 and June 14, 2023, a comprehensive collection of publications on the topic of interspinous devices in the treatment of lumbar degenerative disease (IDTLDD) was procured from the Web of Science. A bibliometric analysis and visualization were subsequently conducted, utilizing various tools including HisCite, VOSviewer, CiteSpace, and bibliometrix package. This process involved the gathering of data on the country, institution, author, journal, reference, and keywords. A comprehensive analysis of 401 publications sourced from 149 journals was conducted, with 1718 authors affiliated with 1188 institutes across 240 countries/regions. Notably, the United States emerged as the leading contributor with 134 published articles on interspinous devices in the treatment of lumbar degenerative disease (33.42%). The most productive institution was Capital Medical University, with (10, 2.49%) publications. The author with the highest publication output was Block, Jon E, with 10 publications. European Spine Journal demonstrated the highest level of productivity, with a publication of (n = 39, 9.73%). The term "X-Stop" was the most frequently utilized keyword, followed by "Lumbar spinal stenosis." The study identified various topics of current interest, such as "Invasive decompression" and "Coflex." The present study provides a comprehensive survey of research trends and developments in the application of interspinous device for the treatment of lumbar degenerative diseases, including relevant research findings and collaborative efforts among authors, institutions, and countries.
    DOI:  https://doi.org/10.1097/MD.0000000000037351
  25. Ocul Immunol Inflamm. 2023 Oct 05. 1-16
    Revealing Academic Evolution and Frontier Pattern in the Field of Uveitis Using Bibliometric Analysis, Natural Language Processing, and Machine Learning.
    Ao Lu, Keyan Li, Guannan Su, Peizeng Yang.
       PURPOSE: Numerous uveitis articles were published in this century, underneath which hides valuable intelligence. We aimed to characterize the evolution and patterns in this field.
    METHODS: We divided the 15,994 uveitis papers into four consecutive time periods for bibliometric analysis, and applied latent Dirichlet allocation topic modeling and machine learning techniques to the latest period. .
    RESULTS: The yearly publication pattern fitted the curve: 1.21335x2 - 4,848.95282x + 4,844,935.58876 (R2 = 0.98311). The USA, the most productive country/region, focused on topics like ankylosing spondylitis and biologic therapy, whereas China (mainland) focused on topics like OCT and Behcet disease. The logistic regression showed the highest accuracy (71.6%) in the test set.
    CONCLUSION: In this century, a growing number of countries/regions/authors/journals are involved in the uveitis study, promoting the scientific output and thematic evolution. Our pioneering study uncovers the evolving academic trends and frontier patterns in this field using bibliometric analysis and AI algorithms.
    Keywords:  Artificial intelligence; machine learning; natural language processing; uveitis
    DOI:  https://doi.org/10.1080/09273948.2023.2262028
  26. Heliyon. 2024 Feb 29. 10(4): e26472
    The evolution of smart hotels: A bibliometric review of the past, present and future trends.
    Xiaoyan Liu, Walton Wider, Muhammad Ashraf Fauzi, Leilei Jiang, Lester Naces Udang, Syed Far Abid Hossain.
      This study provides a bibliometric analysis of smart hotel research, drawing from 613 publications in the Web of Science (WoS) database to examine scholarly trends and developments in this dynamic field. Smart hotels, characterized by integrating advanced technologies such as AI, IoT, cloud computing, and big data, aim to redefine customer experiences and operational efficiency. Utilizing co-citation and co-word analysis techniques, the research delves into the depth of literature from past to future trends. In co-citation analysis, clusters including "Sustainable Hotel and Green Hotel", "Theories Integration in Smart Hotel Research", and "Consumers' Decisions about Green Hotels" underscore the pivotal areas of past and current research. Co-word analysis further reveals emergent trend clusters: "The New Era of Sustainable Tourism", "Elevating Standards and Guest Loyalty", and "Hotels' New Sustainable Blueprint in Modern Travel". These clusters reflect the industry's evolving focus on sustainability and technology-enhanced guest experiences. Theoretically, this research bridges gaps in smart hotel literature, proposing new frameworks for understanding customer decisions amid technological advancements and environmental responsibilities. Practically, it offers valuable insights for hotel managers, guiding technology integration strategies for enhanced efficiency and customer loyalty while underscoring the critical role of green strategies and sustainability.
    Keywords:  Bibliometric analysis; Co-citation analysis; Co-word analysis; Smart hotels; Sustainable tourism
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e26472
  27. Cureus. 2024 Jan;16(1): e53028
    Bibliometric Indices As Indicators of Research Output: Analyzing Anesthesiologists as a Paradigm for Surgical Disciplines.
    Shooka Esmaeeli, Dhanesh D Binda, Luis F Rendon, Connor M Logan, Jacob L Leung, Hannah M Nguyen, Cara E Michael, Maxwell B Baker, Lan Xu, Ala Nozari.
      Anesthesiology is one of the increasingly competitive surgical specialties with a growing emphasis on scholarly activity. A metric of productivity and citation influence, the Hirsch index (h-index), can help identify mentors capable of guiding postgraduate trainees toward successful academic achievements. This study sought to determine associations between h-indices or m-quotients and manuscript publication in anesthesiology. Using the American Society of Anesthesiologists (ASA) website, accepted abstracts from the ASA Annual Meetings from 2019 to 2021 were screened (n=2146). The first author (FAHi) and senior author (SAHi) h-indices, as well as the first author (FAMq) and senior author (SAMq) m-quotients, were collected for each abstract using the Scopus database. Whether an accepted abstract was subsequently published as a manuscript in a peer-reviewed journal was also noted, along with the number of days between ASA presentation and publication date. Linear and logistic regression models were used for statistical analyses. In total, 348 (34.4%) of the 1012 eligible abstracts were published as manuscripts. Mean FAHi, SAHi, FAMq, and SAMq, were significantly higher for accepted ASA abstracts that were later published in peer-reviewed journals compared to accepted abstracts that were not published (p<0.001). FAHi, SAHi, FAMq, and SAMq had significant positive associations with odds of publication (p=0.002; p<0.001; p=0.006; p<0.001, respectively). There was no statistical significance between FAHi, SAHi, FAMq, or SAMq and the number of days between ASA presentation and publication. Our study uniquely demonstrates the positive, direct association between h-indices and m-quotients with the probability of publication in anesthesiology. We propose that bibliometric indices are adapted to provide a refined perspective of a physician-scientist's capabilities. Postgraduate trainees can use these indices to discern research mentors primed to foster academic excellence.
    Keywords:  academic productivity; bibliometrics analysis; h-index; m-quotient; research evaluation
    DOI:  https://doi.org/10.7759/cureus.53028
  28. J Orthop. 2024 Jan;47 148-150
    The progress report of the Journal of Orthopaedics.
    Raju Vaishya, P Gopinathan.
      The Journal of Orthopaedics is one of the leading and fast-growing Orthopaedic journals from Asia (and India). It has demonstrated an increase in all the important journal metrics like submissions, citations, h-index, and Cite Score and has achieved its first journal impact factor in 2022.
    DOI:  https://doi.org/10.1016/j.jor.2024.02.001
  29. Heliyon. 2024 Feb 29. 10(4): e25995
    Trends in gut-heart axis and heart failure research (1993-2023): A bibliometric and visual analysis.
    Jiahui Ouyang, Lingli Zhao, Yewen Song, Hua Qu, Tianyi Du, Liu Shi, Zhijie Cui, Zhonghui Jiang, Zhuye Gao.
       Background: The incidence of heart failure, the terminal stage of several cardiovascular diseases, is increasing owing to population growth and aging. Bidirectional crosstalk between the gut and heart plays a significant role in heart failure. This study aimed to analyze the gut-heart axis and heart failure from a bibliometric perspective.
    Methods: We extracted literature regarding the gut-heart axis and heart failure from the Web of Science Core Collection database (January 1, 1993, to June 30, 2023) and conducted bibliometric and visualization analyses using Microsoft Excel, CiteSpace, VOSviewer, and the R package "bibliometrix."
    Results: The final analysis included 1646 articles with an average of 35.38 citations per article. Despite some fluctuations, the number of articles published per year has steadily increased over the past 31 years, particularly since 2018. A total of 9412 authors from 2287 institutions in 86 countries have contributed to this field. The USA and China have been the most productive countries, with the Cleveland Clinic in the USA and Charité-Universitätsmedizin Berlin in Germany being the most active institutions. The cooperation between countries/regions and institutions was relatively close. Professor Tang WHW was the most productive author in the field and the journal Shocks published the highest number of articles. "Heart failure," "gut microbiota," "trimethylamine N-oxide," and "inflammation" were the most common keywords, representing the current research hotspots. The keyword burst analysis indicated that "gut microbiota" and "short-chain fatty acids" are the current frontier research topics in this field.
    Conclusion: Research on the gut-heart axis and heart failure is increasing. This bibliometric analysis indicated that the mechanisms associated with the gut-heart axis and heart failure, particularly the gut microbiota, trimethylamine N-oxide, inflammation, and short-chain fatty acids, will become hotspots and emerging trends in research in this field. These findings provide valuable insights into current research and future directions.
    Keywords:  Bibliometric analysis; Gut microbiota; Gut-heart axis; Heart failure; Inflammation; Short-chain fatty acids; Trimethylamine N-Oxide
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e25995
  30. Front Psychol. 2024 ;15 1265781
    School refusal: mapping the literature by bibliometric analysis.
    Sümeyye Ulaş, Carolina Gonzálvez, İsmail Seçer.
      School refusal is considered a risk factor for academic, social, and personal situations, such as school dropouts. Studies have been carried out on school refusal for almost 50 years. However, general research trends have not been mapped yet. This study summarizes the bibliometric analysis of scientific collaborations and prevalence across locations by country and institution, leading researchers, journals, and trends (keywords) in school refusal research. The United States, Japan, Spain, and England are the countries that stand out in terms of school refusal. It can be said that the Journal of American Academy of Child and Adolescent Psychiatry, Cognitive and Behavioral Practice, and Frontiers in Psychology are important journals that publish on school refusal. Researchers named Christopher A. Kearney, Carolina Gonzálvez, Jose Manuel Garcia-Fernandez, David A. Heyne, and Brigit M. Van Widenfelt have been found to have more intensive studies and collaborations on school refusal. The authors keywords common use for school refusal; are truancy, school absenteeism, adolescence, school attendance, school phobia, autism spectrum disorder, and bullying. The findings show that school refusal is a current research area, and scientific collaborations continue to be established. The findings reveal all the details of the school refusal research.
    Keywords:  bibliometric analysis; research trends; school attendance problem; school refusal; scientific collaboration
    DOI:  https://doi.org/10.3389/fpsyg.2024.1265781
  31. J Am Acad Orthop Surg Glob Res Rev. 2024 Mar 01. 8(3):
    The Top 100 Classical and Contemporary Papers on Elbow Surgery: A Trend Analysis of Elbow Surgery Literature.
    Jacob A Worden, Andrew M Gabig, Hayden L Cooke, Michael B Gottschalk, Eric R Wagner.
       INTRODUCTION: Bibliometric analyses provide an aggregate of the most frequently cited literature in a given field. The purpose of this study was to analyze the top 100 most-cited classical and contemporary papers relating to elbow surgery to serve as a reference for surgeons and trainees for educational and research purposes.
    METHODS: A search was conducted for all papers containing the term "elbow" in the categories Orthopedics, Surgery, and Sports Science in the Clarivate Web of Science. Classical papers were those published from 1980 to 2009, and contemporary papers were those published from 2010 to 2019. Articles were assessed by country of origin, authors and their credentials, parent journal, level of evidence, and topic.
    RESULTS: Citation frequency ranged from 86 to 867. Among the classical group, there were more level IV papers compared with level I papers; however, the opposite was true in the contemporary group. The most common topic in the classical group was elbow anatomy and function, and the most common topic in the contemporary group was lateral epicondylitis and medial epicondylitis and associated therapies.
    DISCUSSION: This bibliometric analysis serves to help guide surgeons and trainees on the highly cited articles and important topics in elbow surgery, demonstrating a shift to prospective randomized controlled trials in recent years.
    LEVEL OF EVIDENCE: Level V (Systematic Review with Level V as Lowest LOE).
    DOI:  https://doi.org/e23.00287
  32. Cureus. 2024 Feb;16(2): e55190
    Mapping the Evolution of Clinical Trials on Drug-Resistant Tuberculosis: A Bibliometric Overview (1965-2023).
    Namrata Dagli, Mainul Haque, Santosh Kumar.
      This study provides a comprehensive overview of the current landscape in drug-resistant tuberculosis research. An extensive electronic search was conducted on PubMed and Scopus databases to identify clinical trials related to drug-resistant tuberculosis. Network analysis and visualization were performed on the data using the Biblioshiny App and VOSviewer software. This bibliometric study focuses on revealing publication trends, leading contributors, key institutions, thematic focuses, and citation patterns. The analysis of research paper publications reveals a consistent upward trajectory over the years, characterized by periodic declines and subsequent surges. Noteworthy peaks in 2013 and 2010 are observed in Scopus and PubMed, respectively, followed by marked declines, particularly notable between 2021 and 2023. PubMed and Scopus data indicate that the United States and South Africa are the leading contributors. According to the PubMed and Scopus databases, the University of Cape Town and Stellenbosch University are the institutions that contribute the most. Keyword and thematic analyses underscore the primary research focuses on drug-resistant tuberculosis (DR-TB), including drug combination therapy, microbiological analysis of sputum, therapeutic uses of antitubercular agents, drug resistance (DR), multidrug resistance (MDR), and Mycobacterium tuberculosis. The trend-topic analysis reveals dynamic shifts in research focus over time, transitioning from single-drug therapy to addressing drug resistance and highlighting the emerging need for effective drug therapy in cases of multidrug-resistant tuberculosis. Notably, most research papers on drug-resistant tuberculosis are single-country publications. Citation analysis in the Scopus database indicates that the average citation per year and mean total citation per year peaked during 2005-2006. This suggests a period of heightened impact and recognition within the research community during that timeframe. The study's findings may inform strategic planning for combating drug-resistant tuberculosis, ultimately contributing to future enhanced prevention, diagnosis, and treatment strategies.
    Keywords:  bibliometric; citation analysis; clinical trials; drug-resistant; multidrug-resistant; mycobacterium; network analysis; network visualization; overlay visualization; tuberculosis
    DOI:  https://doi.org/10.7759/cureus.55190
  33. Curr Med Imaging. 2024 Feb 27.
    Clinical Application of MRI in Coronavirus Disease 2019: A Bibliometric Analysis.
    Jinqun Hu, Jian Xiong, Jing Jiang, Ying Wei, Fayang Ling, Shichun Luo, Jiao Chen, Chengguo Su, Xiao Wang, Wenchuan Qi, Fanrong Liang.
       BACKGROUND: Currently, coronavirus disease 2019 (COVID-19) continues to remain in the pandemic stage, leading to severe challenges in the global public healthcare system. Magnetic resonance imaging (MRI) methods have played an important role in the diagnosis of COVID-19 and the structural evaluation of the affected organs. Reviewing and summarizing the application of MRI has significant clinical implications for COVID-19.
    OBJECTIVE: The study aimed to analyze literature related to the application of MRI in COVID-19 using bibliometric tools, to explore the research status, hotspots, and developmental trends in this field, and to provide a reference for the application of MRI in the clinical diagnosis and evaluation of COVID-19.
    METHODS: We used the Web of Science Core Collection database to search and collect relevant literature on the use of MRI in COVID-19. The authors, institutes, countries, journals, and keyword modules of the bibliometric analysis software CiteSpace and VOSviewer were used to analyze and plot the network map.
    RESULTS: A total of 1506 relevant articles were shortlisted through the search; the earliest study was published in 2019, showing an overall upward trend every year. The research was mainly presented as published articles. Clinical neurology was found to be the primary discipline. The United States had the highest publication volume and influence in this field. Countries around the world cooperated more closely. The Cureus Journal of Medical Science was the main periodical to publish articles. Institutes, such as Harvard Medical School, Mayo Clinic, and Massachusetts General Hospital, have published a large number of papers. Some of the high-frequency keywords were "COVID-19", "SARS-CoV-2", "magnetic resonance", "myocarditis", and "cardiac magnetic resonance imaging". The keyword clustering study showed that the current research mainly focuses on five "hot" directions.
    CONCLUSION: There is a need to strengthen cross-teamwork and multidisciplinary collaboration in the future to completely explore the positive role of MRI in COVID-19 and to discover breakthroughs for the challenges in the clinical diagnosis and treatment of COVID-19.
    Keywords:  MRI; MRI technology; COVID-19; Citespace; VOSviewer; bibliometric analysis Knowledge graph.
    DOI:  https://doi.org/10.2174/0115734056274864231227071026
  34. Front Sociol. 2024 ;9 1337742
    A bibliometric review study of Michael Burawoy.
    Aditya Raj, Anushka Sinha.
      This review article utilizes the technique of citation-based bibliometric analysis to provide a comprehensive understanding of the scholarly contributions made by sociologist Michael Burawoy. The most influential academic articles published by Burawoy were retrieved for analyses. Following this, scholars, journals and institutions that he most frequently collaborated with were traced. Further, country-wise analysis of his scholarship was carried out. Lastly, content analyses of retrieved articles identified prominent thematic domains in sociology to which Burawoy contributed, while temporal analyses helped to identify some emerging research hotspots. Findings reveal that historical and cultural context of Burawoy's research mostly remained confined to the U.S.A., however, he significantly contributed towards the foundation of sociology in the Global South and studied the ensuing global power imbalances. Contemporary sociological thought remains indebted to Burawoy for his comparative study of industrial relations in the 21st century, and recently, his elaboration upon the need for public sociology has taken the discipline in new intellectual directions that appeals to a broader sociological community.
    Keywords:  Global South; Michael Burawoy; bibliometric review; public sociology; systematic review
    DOI:  https://doi.org/10.3389/fsoc.2024.1337742
  35. Quant Imaging Med Surg. 2024 Feb 01. 14(2): 1873-1890
    Revolutionizing vascular imaging: trends and future directions of 4D flow MRI based on a 20-year bibliometric analysis.
    Peisong Ma, Lishu Zhu, Ru Wen, Fajin Lv, Yongmei Li, Xinyou Li, Zhiwei Zhang.
       Background: Four-dimensional flow magnetic resonance imaging (4D flow MRI) is a promising new technology with potential clinical value in hemodynamic quantification. Although an increasing number of articles on 4D flow MRI have been published over the past decades, few studies have statistically analyzed these published articles. In this study, we aimed to perform a systematic and comprehensive bibliometric analysis of 4D flow MRI to explore the current hotspots and potential future directions.
    Methods: The Web of Science Core Collection searched for literature on 4D flow MRI between 2003 and 2022. CiteSpace was utilized to analyze the literature data, including co-citation, cooperative network, cluster, and burst keyword analysis.
    Results: A total of 1,069 articles were extracted for this study. The main research hotspots included the following: quantification and visualization of blood flow in different clinical settings, with keywords such as "cerebral aneurysm", "heart", "great vessel", "tetralogy of Fallot", "portal hypertension", and "stiffness"; optimization of image acquisition schemes, such as "resolution" and "reconstruction"; measurement and analysis of flow components and patterns, as indicated by keywords "pattern", "KE", "WSS", and "fluid dynamics". In addition, international consensus for metrics derived from 4D flow MRI and multimodality imaging may also be the future research direction.
    Conclusions: The global domain of 4D flow MRI has grown over the last 2 decades. In the future, 4D flow MRI will evolve towards becoming a relatively short scan duration with adequate spatiotemporal resolution, expansion into the diagnosis and treatment of vascular disease in other related organs, and a shift in focus from vascular structure to function. In addition, artificial intelligence (AI) will assist in the clinical promotion and application of 4D flow MRI.
    Keywords:  CiteSpace; Four-dimensional flow magnetic resonance imaging (4D flow MRI); Web of Science; bibliometric analysis; visualization analysis
    DOI:  https://doi.org/10.21037/qims-23-1227
  36. Front Psychiatry. 2024 ;15 1304916
    A bibliometric analysis of autism spectrum disorder signaling pathways research in the past decade.
    Kaifeng Lyu, Jiangshan Li, Min Chen, Wu Li, Wei Zhang, Meichao Hu, Yuxing Zhang, Xiang Feng.
       Background: This study employs bibliometric methods to comprehensively understand the fundamental structure of research about Autism Spectrum Disorder (ASD) Signaling Pathways by examining key indicators such as nations, institutions, journals, authors, and keywords.
    Methodology: We utilized the WoScc database to retrieve literature relevant to ASD Signaling Pathways published between 2013 and 2023. Through visual analysis and tools like CiteSpace and VosViewer, we explored nations, institutions, journals, authors, and keywords, thereby constructing relevant networks.
    Results: 26 The study encompasses 1,396 articles, revealing a consistent increase in publications. The United States, China, and Germany are leading nations in this literature. Regarding research institutions, the University of California system and Eric Klann have garnered significant attention due to their substantial contributions to the field of ASD Signaling Pathways. Most relevant research is published in the journal "Molecular Autism." Research interests are concentrated across various themes, including "elevating neuronal β-catenin levels," "Tunisian children," "Fmr1 knockout (KO) mice," "de novo mutations," "autistic children," "local translation," "propionic acid-induced mouse models," "neurosystems," "glucose metabolism," and "neuronal migration." Future research may emphasize exploring aspects such as gut microbiota, genes, stress, maternal immune activation, memory, and neurodevelopmental disorders of ASD.
    Conclusion: This study, through bibliometric analysis of key indicators such as nations, institutions, journals, authors, and keywords, provides a comprehensive overview of the current state of research on ASD Signaling Pathways. These investigations predominantly focus on molecular mechanisms, animal model studies, population-based research, and the structure and function of neurosystems. Future research directions are also clearly proposed. First, in-depth research on the genes and neurodevelopmental disorders associated with ASD will continue to reveal the genetic basis and provide support for precise treatments. At the same time, attention to the gut microbiota will help explore its association with ASD, which may provide clues for new treatments. In addition, the relationship between stress and ASD will become the focus of research to understand better the emotional and behavioral characteristics of ASD patients in stressful situations. Maternal immune activation will also be further studied to explore how environmental factors influence the risk and development of ASD. Finally, a deeper understanding of the cognitive functions of patients with ASD, especially memory and learning, will help develop individualized treatment strategies to improve patients' quality of life. These directions will work together and are expected to provide a more comprehensive understanding of Signaling Pathways research in ASD and provide new ideas and opportunities for future intervention and treatment.
    Keywords:  ASD; Citespace; VOSviewer; bibliometric analysis; signaling pathways
    DOI:  https://doi.org/10.3389/fpsyt.2024.1304916
  37. Medicine (Baltimore). 2024 Mar 01. 103(9): e37268
    Top-50 cited articles on cysticercosis and neurocysticercosis.
    Gregorio Gonzalez-Alcaide, Nestor Sosa, Fatima Valero-Samper, Isabel Belinchon-Romero, Jose-Manuel Ramos-Rincon.
       BACKGROUND: Identifying the most highly cited papers in a given field can help researchers and professionals understand the milestones and research areas that are generating the most impact. This study aimed to identify and describe the 50 most frequently cited manuscripts on cysticercosis and neurocysticercosis.
    METHODS: We identified the 50 most cited papers (articles and reviews) on cysticercosis and neurocysticercosis from the MEDLINE database and indexed in Web of Science-Core Collection, analyzing their bibliographic and content characteristics.
    RESULTS: The most cited documents comprised 29 (58%) original articles and 21 (42%) reviews, the bulk of which were narrative reviews (n = 17), with a negligible presence of other types of reviews with high-level scientific evidence. Six journals published 42% of the articles. In addition to the USA, Mexico and Peru were prominent countries of origin among leading researchers. The main research topics were the central nervous system and epilepsy on the one hand, and diagnostic and therapeutic approaches on the other.
    CONCLUSION: Our findings shed light on the dissemination of knowledge about cysticercosis and neurocysticercosis in recent decades, identifying the most highly cited contributions that have driven research in the field.
    DOI:  https://doi.org/10.1097/MD.0000000000037268
  38. Environ Sci Pollut Res Int. 2024 Feb 24.
    Current trends and future directions of global research on wastewater to energy: a bibliometric analysis and review.
    Zhining Shi, Ke Xing, Rameez Rameezdeen, Christopher W K Chow.
      This paper presents a structured bibliometric analysis and review of the research publications recorded in the Web of Science database from 2000 to 2023 to methodically examine the landscape and development of the 'wastewater to energy' research field in relation to global trends, potential hotspots, and future research directions. The study highlights three main research themes in 'wastewater to energy', which are biogas production through anaerobic digestion of sewage sludge, methane generation from microbial wastewater treatment, and hydrogen production from biomass. The analysis reveals activated sludge, biochar, biomethane, biogas upgrading, hydrogen, and circular economy as key topics increasingly gaining momentum in recent research publications as well as representing potential future research directions. The findings also signify transformation to SDGs and circular economy practices, through the integration of on-site renewables and biogas upgrading for energy self-sufficiency, optimising energy recovery from wastewater treatment systems, and fostering research and innovation in 'wastewater to energy' supported by policy incentives. By shedding light on emerging trends, cross-cutting themes, and potential policy implications, this study contributes to informing both knowledge and practices of the 'wastewater to energy' research community.
    Keywords:  Anaerobic; Bibliometric analysis; Biogas; Energy; Hydrogen; Wastewater
    DOI:  https://doi.org/10.1007/s11356-024-32560-2
  39. J Thorac Dis. 2024 Jan 30. 16(1): 12-25
    Visual analysis of the research literature on extracorporeal membrane oxygenation-assisted support for respiratory failure based on CiteSpace and VOSviewer: a 20-year study.
    Wei Wang, Bin Xiong, Shulin Xiang, Jianyu Ji, Jing Pang, Lin Han.
       Background: This study aims to visually assess the bibliometric status, current hotspots, and development trends in the field of extracorporeal membrane oxygenation (ECMO)-assisted support for respiratory failure through an examination of articles pertaining to ECMO-assisted support for respiratory failure.
    Methods: A search was conducted on pertinent literature in the domain of ECMO-assisted support for respiratory failure published from 2003 to 2023, utilizing the Web of Science Core Collection (WOSCC) database. A bibliometric analysis was conducted using CiteSpace and VOSviewer visualization software to identify and assess associations between keywords, countries, institutions, authors, journals, and references.
    Results: The present study incorporated a compilation of 1,901 pertinent articles. The United States published the maximum number of research articles in this field, and was closely followed by Germany and China. Furthermore, the University of Michigan was the leading institution in ECMO research. In this context, Daniel Brodie, an American expert, significantly contributed to this field and had published 107 related articles on the subject. Concurrently, active collaboration among ECMO researchers was also observed. Asaio Journal was the most prolific contributor, and Giles J. Peek, 2009, published in Lancet, comprised the most cited article in the field. Additionally, the analysis of keywords could be divided into three categories: (I) neonatal ECMO; (II) complications of ECMO; (III) ECMO application in coronavirus disease 2019 (COVID-19); (IV) application of point-of-care ultra sound in ECMO.
    Conclusions: This study employed CiteSpace and VOSviewer to conduct a systematic literature review on ECMO-assisted support for respiratory failure from 2003 to 2023 in the Web of Science core database. The research outcomes in this domain were presented, offering researchers references for them to gain an accurate understanding of the current state of research and emerging trends in this field.
    Keywords:  Extracorporeal membrane oxygenation (ECMO); Web of Science; bibliometrics; respiratory failure; visual analysis
    DOI:  https://doi.org/10.21037/jtd-23-1184
  40. World J Gastrointest Oncol. 2024 Feb 15. 16(2): 527-542
    Global research trends and prospects of cellular metabolism in colorectal cancer.
    Yan-Chen Liu, Zhi-Cheng Gong, Chao-Qun Li, Peng Teng, Yan-Yan Chen, Zhao-Hui Huang.
       BACKGROUND: An increasing number of studies have focused on the role of cellular metabolism in the development of colorectal cancer (CRC). However, no work is currently available to synthesize the field through bibliometrics.
    AIM: To analyze the development in the field of "glucose metabolism" (GM), "amino acid metabolism" (AM), "lipid metabolism" (LM), and "nucleotide metabolism" (NM) in CRC by visualization.
    METHODS: Articles within the abovementioned areas of GM, AM, LM and NM in CRC, which were published from January 1, 1991, to December 31, 2022, are retrieved from the Web of Science Core Collection and analyzed by CiteSpace 6.2.R4 and VOSviewer 1.6.19.
    RESULTS: The field of LM in CRC presented the largest number of annual publications and the fastest increase in the last decade compared with the other three fields. Meanwhile, China and the United States were two of the most prominent contributors in these four areas. In addition, Gang Wang, Wei Jia, Maria Notarnicola, and Cornelia Ulrich ranked first in publication numbers, while Jing-Yuan Fang, Senji Hirasawa, Wei Jia, and Charles Fuchs were the most cited authors on average in these four fields, respectively. "Gut microbiota" and "epithelial-mesenchymal transition" emerged as the newest burst words in GM, "gut microbiota" was the latest outburst word in AM, "metastasis", "tumor microenvironment", "fatty acid metabolism", and "metabolic reprogramming" were the up-to-date outbreaking words in LM, while "epithelial-mesenchymal transition" and "apoptosis" were the most recently occurring words in NM.
    CONCLUSION: Research in "cellular metabolism in CRC" is all the rage at the moment, and researchers are particularly interested in exploring the mechanism to explain the metabolic alterations in CRC. Targeting metabolic vulnerability appears to be a promising direction in CRC therapy.
    Keywords:  Amino acid metabolism; Cellular metabolism; Colorectal cancer; Glucose metabolism; Lipid metabolism; Nucleotide metabolism
    DOI:  https://doi.org/10.4251/wjgo.v16.i2.527
  41. Hum Vaccin Immunother. 2024 Dec 31. 20(1): 2318815
    Immune regulation and the tumor microenvironment in anti-PD-1/PDL-1 and anti-CTLA-4 therapies for cancer immune evasion: A bibliometric analysis.
    Yi Huang, Zhijian Chen, Gang Shen, Shuogui Fang, Junjiong Zheng, Zepai Chi, Yuanfeng Zhang, Yitong Zou, Qinghua Gan, Chengxiao Liao, Yuhui Yao, Jianqiu Kong, Xinxiang Fan.
      This study aims to conduct a bibliometric analysis, employing visualization tools to examine literature pertaining to tumor immune evasion related to anti-CTLA-4 and anti-PD-1/PD-L1 therapy from 1999 to 2022. A special emphasis is placed on the interplay between tumor microenvironment, signaling pathways, immune cells and immune evasion, with data sourced from the Web of Science core collection (WoSCC). Advanced tools, including VOSviewer, Citespace, and Scimago Graphica, were utilized to analyze various parameters, such as co-authorship/co-citation patterns, regional contributions, journal preferences, keyword co-occurrences, and significant citation bursts. Out of 4778 publications reviewed, there was a marked increase in research focusing on immune evasion, with bladder cancer being notably prominent. Geographically, China, the USA, and Japan were the leading contributors. Prestigious institutions like MD Anderson Cancer Center, Harvard Medical School, Fudan University, and Sun Yat Sen University emerged as major players. Renowned journals in this domain included Frontiers in Immunology, Cancers, and Frontiers in Oncology. Ehen LP and Wang W were identified as prolific authors on this topic, while Topalian SL stood out as one of the most cited. Research current situation is notably pivoting toward challenges like immunotherapy resistance and the intricate signaling pathways driving drug resistance. This bibliometric study seeks to provide a comprehensive overview of past and current research trends, emphasizing the potential role of tumor microenvironment, signaling pathways and immune cells in the context of immune checkpoint inhibitors (ICIs) and tumor immune evasion.
    Keywords:  CLTA-4; Immune checkpoint inhibitors (ICIs); PD-1/PD-L1; bibliometrics; immune evasion
    DOI:  https://doi.org/10.1080/21645515.2024.2318815
  42. J Neurosurg. 2024 Mar 01. 1-9
    Preresidency research output among US neurological surgery residents.
    Rishabh Gupta, Jeffrey Chen, Steven Roth, Naveed Kamal, Breanne Reisen, Alexander Ortiz, Michael Feldman, Nishit Mummareddy, Jacob Jo, Lola Chambless.
       OBJECTIVE: Research productivity is often used to evaluate candidates for neurosurgery residency. Official annual reports describe the mean total number of research products of successful applicants for each match cycle; however, the average number of indexed publications, the highest-valued research product, is not reported separately from other research products. The primary objectives of this study were to describe the distribution of preresidency indexed publication quantity among successful neurosurgery applicants from 2017 to 2021 and determine whether any change in publication quantity across application cycles existed. Secondary objectives included determining the rate at which the average publication quantity is increasing across application cycles, whether this increase is driven by high-output applicants alone, and if a performance ceiling has been reached.
    METHODS: US doctor of medicine seniors applying to the senior author's institution between 2017 and 2021 and who successfully matched into any US neurosurgery program were included. Publication quantities were extracted using Scopus. Additional variables were extracted from residency applications. Mean (SD) and median (IQR) publication quantities were used to describe the distribution and compare across years. Applicants were ranked by descending publication count and divided into quartiles. Averages within each quartile were compared with respective quartiles across years. Averages of the top 10% most productive applicants were compared across years to determine if a performance ceiling existed.
    RESULTS: Overall, 93.2% of matched applicants were captured. The mean and median total numbers of publications for applicants who matched from 2017 to 2021 were 5.6 ± 8.3 and 3.0 (1.0, 7.0), respectively. The mean and median numbers of publications increased from 3.7 ± 5.3 and 2.0 (0.0, 5.0) in 2016-2017 to 8.1 ± 10.0 and 5.0 (2.0, 11.0) in 2020-2021 (p < 0.001). The distribution of publication quantity was right-skewed. Multivariable analysis determined the application year to be independently and positively correlated with publication quantity (β 1.07 [95% CI 0.71-1.42], p < 0.001). All quartiles observed an increased average number of publications across years (p < 0.001). The mean and median numbers for the top 10% increased from 15.8 ± 8.7 and 13.0 (10.8, 15.5) in 2016-2017, respectively, to 31.3 ± 16.0 and 25.0 (21.0, 35.5) in 2020-2021 (p < 0.001).
    CONCLUSIONS: Indexed publications account for a small portion of the total research products that successful neurosurgery candidates list on applications. A high number of publications is not necessary for candidates to match, with approximately 50% of all applicants who successfully matched having ≤ 5 publications and 25% having ≤ 2 publications. The average preresidency publication quantity has been increasing yearly among neurosurgery applicants. This increase was present across the applicant pool. Additionally, no performance ceiling was observed.
    Keywords:  match; medical education; neurosurgery; neurosurgical education; research; residency
    DOI:  https://doi.org/10.3171/2023.12.JNS231029
  43. BMJ Open Ophthalmol. 2024 Feb 27. pii: e001323. [Epub ahead of print]9(1):
    Research productivity and gender of research award recipients in international ophthalmology societies.
    Anne Xuan-Lan Nguyen, Dipti Satvi Venkatesh, Ankita Biyani, Sanyam Ratan, Gun Min Youn, Albert Y Wu.
       PURPOSE: The purpose of this study is to assess the research productivity and gender of award recipients of ophthalmology research awards in international societies.
    METHODS: This is a retrospective, observational study. The study population included award recipients of research awards from 36 ophthalmologic societies (listed on the International Council of Ophthalmology database) in 99 years (1922-2021). A gender-specific pronoun and a photograph of each award recipient were extracted from professional websites to assign their gender. Research productivity levels were retrieved from the Elsevier Scopus author database. The main outcome measures were gender distribution of award recipients per year, mean h-index per year, mean m-quotient per year, mean h-index by society, and mean m-quotient by society.
    RESULTS: Out of 2506 recipients for 122 awards, 1897 (75.7%) were men and 609 (24.3%) were women. The proportion of woman recipients increased from 0% in 1922 to 41.0% in 2021. Compared with 2000-2010 (19.8%, 109 of 550), women received a greater proportion of awards (48.4%, 459 of 949) in the last decade, from 2011 to 2021. Furthermore, men more often had greater h-index scores and m-quotient scores.
    CONCLUSIONS: Women received awards (24.3%) at a lower rate than men (75.7%) while also exhibiting lower productivity, supporting the existence of a gender disparity. Our study found that women are under-represented in research awards, and further investigation into award selection processes and gender membership data is recommended.
    Keywords:  Epidemiology
    DOI:  https://doi.org/10.1136/bmjophth-2023-001323
  44. Int J Cardiol Heart Vasc. 2024 Feb;50 101328
    The impact of Twitter/X promotion on visibility of research articles: Results of the #TweetTheJournal study.
    Konstanze Betz, Melania Giordano, Henrike Aenne Katrin Hillmann, David Duncker, Dobromir Dobrev, Dominik Linz.
       Aim: Social media (SoMe) are emerging as important tools for research dissemination. Twitter/X promotion has been shown to increase citation rates in well-established journals. We aimed to test the effect of a SoMe promotion strategy on the Mendeley reader counts, the Altmetric Attention Score and the number of citations in an upcoming open-access journal.
    Methods: The #TweetTheJournal study is a randomized, controlled study. Articles published in seven subsequent issues of the International Journal of Cardiology Heart & Vasculature (April 2021-April 2022) were randomized to a Twitter/X promotion arm (articles were posted four times) and to a control arm (without active posting). Articles with accompanied editorials were excluded. Primary endpoint of the study was Mendeley reader count, secondary endpoints were Altmetric Attention Score and number of citations. Follow-up was one year.
    Results: SoMe promotion of articles showed no statistically significant difference in Mendeley reader counts or number of citations at one year follow up. SoMe promotion resulted in a statistically significant higher Altmetric Attention Score in the intervention compared to the control group (RR 1.604, 95 % CI 1.024-2.511, p = 0.039). In the overall group, Altmetric Attention Score showed a correlation with Mendeley reader counts (Spearman's ρ = 0.202, p = 0.010) and Mendeley reader counts correlated significantly with number of citations (Spearman's ρ = 0.372, p < 0.001).
    Conclusion: A dedicated SoMe promotion strategy did not result in statistically significant differences in early impact indicators as the Mendeley reader count in a upcoming journal, but increased the Altmetric Attention Score.
    Keywords:  Altmetrics; Cardiovascular articles; Citations; Mendeley reader; Randomized study; Social media
    DOI:  https://doi.org/10.1016/j.ijcha.2023.101328
  45. Resusc Plus. 2024 Jun;18 100584
    Using generative artificial intelligence in bibliometric analysis: 10 years of research trends from the European Resuscitation Congresses.
    Nino Fijačko, Ruth Masterson Creber, Benjamin S Abella, Primož Kocbek, Špela Metličar, Robert Greif, Gregor Štiglic.
       Aims: The aim of this study is to use generative artificial intelligence to perform bibliometric analysis on abstracts published at European Resuscitation Council (ERC) annual scientific congress and define trends in ERC guidelines topics over the last decade.
    Methods: In this bibliometric analysis, the WebHarvy software (SysNucleus, India) was used to download data from the Resuscitation journal's website through the technique of web scraping. Next, the Chat Generative Pre-trained Transformer 4 (ChatGPT-4) application programming interface (Open AI, USA) was used to implement the multinomial classification of abstract titles following the ERC 2021 guidelines topics.
    Results: From 2012 to 2022 a total of 2491 abstracts have been published at ERC congresses. Published abstracts ranged from 88 (in 2020) to 368 (in 2015). On average, the most common ERC guidelines topics were Adult basic life support (50.1%), followed by Adult advanced life support (41.5%), while Newborn resuscitation and support of transition of infants at birth (2.1%) was the least common topic. The findings also highlight that the Basic Life Support and Adult Advanced Life Support ERC guidelines topics have the strongest co-occurrence to all ERC guidelines topics, where the Newborn resuscitation and support of transition of infants at birth (2.1%; 52/2491) ERC guidelines topic has the weakest co-occurrence.
    Conclusion: This study demonstrates the capabilities of generative artificial intelligence in the bibliometric analysis of abstract titles using the example of resuscitation medicine research over the last decade at ERC conferences using large language models.
    Keywords:  Bibliometrics analysis; Congress; Emergency medicine; European Resuscitation Council; Generative artificial intelligence
    DOI:  https://doi.org/10.1016/j.resplu.2024.100584
  46. Water Sci Technol. 2024 Feb;89(4): 1063-1081
    Progress of evapotranspiration research based on VOSviewer: A review.
    Zetian Yang, Tianling Qin, Huiliang Wang.
      Evapotranspiration (ET) is a key link between atmospheric processes and land surface hydrological processes. With the impact of global warming and human activities, research on ET has become a hot topic. Supported by a total of 1,222 Chinese and English literatures from China National Knowledge Infrastructure and the Web of Science Core Collection from 2013 to 2022, this paper adopts the bibliometric visualization method to review the current research progress and future trend of ET with respect to the time of publication, countries, institutions, journals, and research hotspots. The results show that the number of related research articles is increasing rapidly and the journals with high citations are Journal of Hydrology, Agricultural and Forest Meteorology and Agricultural Water Management. The research hotspots have been focused on prototype observation, remote sensing inversion, mechanism equation, model simulation, spatial-temporal analysis, and attribution identification. In the future, there is an urgent need to integrate algorithms such as machine learning and artificial intelligence, to develop higher resolution remote sensing products, to improve the mechanism equations based on precise observations, and to clarify the impact of synergistic effects on ET among the driving factors.
    DOI:  https://doi.org/10.2166/wst.2024.036
  47. Environ Pollut. 2024 Feb 27. pii: S0269-7491(24)00344-0. [Epub ahead of print] 123630
    A systematic evidence map and bibliometric analysis of the behavioural impacts of pesticide exposure on zebrafish.
    Kyle Morrison, Yefeng Yang, Manuela Santana, Malgorzata Lagisz, Shinichi Nakagawa.
      Pesticides are indispensable in agriculture and have become ubiquitous in aquatic environments. Pesticides in natural environments can cause many negative impacts on aquatic species, ranging from mortality to sub-lethal physiological and behavioural changes. The complex sub-lethal impacts of pesticides are routinely tested on model species, with zebrafish (Danio rerio) being regularly used as a behavioural model. Although behavioural ecotoxicology research using zebrafish is increasing rapidly, we lack quantitative evidence to support which pesticides have been tested and how study designs are carried out. This shortcoming not only limits the deliberate planning for future primary studies to fill the knowledge gaps but also hinders evidence synthesis. To provide quantitative evidence of what pesticides are currently studied and what study designs are used, we combined a systematic evidence map approach and bibliometric analysis. This novel method has been coined research weaving and allows us to elicit gaps and clusters in our evidence base, whilst showing connections between authors and institutions. The methodology can be summarised in five primary steps: literature searching, screening, extraction, data analysis and bibliometric analysis. We identified four areas where research on the sub-lethal effects of pesticide exposure on zebrafish is lacking. First, some widely used pesticides, such as neonicotinoids, are understudied. Second, most studies do not report important elements of the study design, namely the sex and the life-stage of the zebrafish. Third, some behaviours, such as impacts of pesticide exposure on zebrafish cognition, are underexplored. And last, we revealed through the bibliometric analysis that most of the research is conducted in developed countries and there is limited cross country co-authorships. Upon identifying these gaps, we offer solutions for each limitation, emphasizing the importance of diverse global research output and cross-country co-authorships. Our systematic evidence map and bibliometric analysis provide valuable insights for helping to guide future research, which can be used to help support evidence-based policy decisions.
    Keywords:  Agrochemicals; Behaviour; Fish; Pollution; Toxicology
    DOI:  https://doi.org/10.1016/j.envpol.2024.123630
  48. Saudi Pharm J. 2024 Apr;32(4): 101991
    Exploring the topic structure and abuse trends of new psychoactive Substance since the 21st century from a bibliometric perspective.
    Xiaolong Hou, Jifen Wang, Ying Zhang, Yufan Zhang, Jianyang Shangguan, Ge Qin, Boxu Chen, Zhenjun Jia, Duo Qi Xu.
      Nowadays, NPS abuse are continuing to expand in terms of harm and scope, due to its cheap and easy to manufacture anywhere in the world. This study reviewed articles related to seven heavily abused NPS to analyze the structure and trends of NPS abuse. A total of 2476 articles were retrieved based on the search strategy for bibliometric analysis. A significant trend of research in recent years was the increasing number of research on synthetic opioids and designer benzodiazepines, but synthetic cannabinoid and synthetic cathinone still dominate, which were mainly concerned with the development of metabolic models and determining methods as well as their abuse characteristics and reasons. However, with the introduction of class-wide ban on synthetic cannabinoid in China and a series of enhancements in other countries, the abuse of it might decrease to some extent, but more than 20 kinds of synthetic cannabinoid beyond the scope of ban in China still reminded researchers of their potential threats. As for synthetic cathinone, an important phenomenon was some of the drugs first identified during certain period might be more widely distributed in the future. Besides, several problems such as the regulation and prevention mode of emerging NPS, development of testing technologies as well as the interpretation and identification of multiple NPS combinations were also worth paying attention to. This study could help entrants better understand the structure of NPS abuse and provided direction for future research in forensic toxicology.
    Keywords:  Abuse; Bibliometric analysis; Forensic toxicology; New Psychoactive Substance (NPS)
    DOI:  https://doi.org/10.1016/j.jsps.2024.101991
  49. J Neurosurg. 2024 Mar 01. 1-8
    Academic accomplishments of Black neurosurgeons in the United States.
    Michelot Michel, Rodeania Peart, Sandra C Yan, Megan E H Still, Kaitlyn Melnick, Ali San, Brandon Gonzalez, Tiffany R Hodges, William C Newman, Nnenna Mbabuike, William W Ashley, Muhammad Abdul Baker Chowdhury, Maryam Rahman.
       OBJECTIVE: Neurosurgery has remained relatively homogeneous in terms of racial and gender diversity, trailing behind national demographics. Less than 5% of practicing neurosurgeons in the United States identify as Black/African American (AA). Research and academic productivity are highly emphasized within the field and are crucial for career advancement at academic institutions. They also serve as important avenues for mentorship and recruitment of diverse trainees and medical students. This study aimed to summarize the academic accomplishments of AA neurosurgeons by assessing publication quantity, h-index, and federal grant funding.
    METHODS: One hundred thirteen neurosurgery residency training programs accredited by the Accreditation Council for Graduate Medical Education in 2022 were included in this study. The American Society of Black Neurosurgeons registry was reviewed to analyze the academic metrics of self-identified Black or AA academic neurosurgeons. Data on the academic rank, leadership position, publication quantity, h-index, and race of neurosurgical faculty in the US were obtained from publicly available information and program websites.
    RESULTS: Fifty-five AA and 1393 non-AA neurosurgeons were identified. Sixty percent of AA neurosurgeons were fewer than 10 years out from residency training, compared to 37.4% of non-AA neurosurgeons (p = 0.001). AA neurosurgeons had a median 32 (IQR 9, 85) publications compared to 52 (IQR 22, 122) for non-AA neurosurgeons (p = 0.019). AA neurosurgeons had a median h-index of 12 (IQR 5, 24) compared to 16 (IQR 9, 31) for non-AA colleagues (p = 0.02). Following stratification by academic rank, these trends did not persist. No statistically significant differences in the median amounts of awarded National Institutes of Health funding (p = 0.194) or level of professorship attained (p = 0.07) were observed between the two cohorts.
    CONCLUSIONS: Racial disparities between AA and non-AA neurosurgeons exist in publication quantity and h-index overall but not when these groups are stratified by academic rank. Given that AA neurosurgeons comprise more junior faculty, it is expected that their academic accomplishments will increase as more enter academic practice and current neurosurgeons advance into more senior positions.
    Keywords:  African American; Black; academics; diversity; h-index; neurosurgical education; research
    DOI:  https://doi.org/10.3171/2023.12.JNS231451
  50. Zhongguo Zhong Yao Za Zhi. 2024 Jan;49(2): 559-564
    [Review and prospect of traditional Chinese medicine in treatment of trauma based on bibliometrics].
    Jing Li, Jing-Jing Ye, Lei Yang.
      This study aims to summarize the research hotspots and trends in traditional Chinese medicine(TCM) treatment of trauma and provide suggestions for collaborative research on the treatment of trauma with integrated Chinese and western medicine. The re-levant research articles on TCM treatment of trauma were searched against CNKI, Wanfang, VIP, Web of Science, and PubMed from inception to December 31, 2022 and analyzed using bibliometric. After screening, 315 articles in Chinese and 34 articles in English were included. The articles were mainly published by TCM journals. The core author groups were absent. The author affiliations were dominated by medical institutions and supplemented by universities, research institutions, and government agencies. The research mainly focused on the clinical practice and trials of TCM in trauma treatment. Although the TCM treatment of trauma emerged early, it is still in the initial stage of development. The future research can focus on innovating the service model of trauma treatment, improving clinical research capability, improving medical quality management, and strengthening the TCM talent teams in comprehensive hospitals. Western medicine is precise and effective in the treatment of trauma, while TCM with unique treatment methods and effects can play a complementary role. Therefore, the trauma treatment with integrated Chinese and western medicine demonstrates a promising prospect.
    Keywords:  bibliometric; prospect; review; traditional Chinese medicine; trauma
    DOI:  https://doi.org/10.19540/j.cnki.cjcmm.20230921.501
  51. J Stroke Cerebrovasc Dis. 2024 Feb 25. pii: S1052-3057(24)00110-1. [Epub ahead of print] 107665
    Trends in Stroke-Related Journals: Examination of Publication Patterns Using Topic Modeling.
    Burak Berksu Ozkara, Mert Karabacak, Konstantinos Margetis, Wade Smith, Max Wintermark, Vivek Srikar Yedavalli.
       OBJECTIVES: This study aims to demonstrate the capacity of natural language processing and topic modeling to manage and interpret the vast quantities of scholarly publications in the landscape of stroke research. These tools can expedite the literature review process, reveal hidden themes, and track rising research areas.
    MATERIALS AND METHODS: Our study involved reviewing and analyzing articles published in five prestigious stroke journals, namely Stroke, International Journal of Stroke, European Stroke Journal, Translational Stroke Research, and Journal of Stroke and Cerebrovascular Diseases. The team extracted document titles, abstracts, publication years, and citation counts from the Scopus database. BERTopic was chosen as the topic modeling technique. Using linear regression models, current stroke research trends were identified. Python 3.1 was used to analyze and visualize data.
    RESULTS: Out of the 35,779 documents collected, 26,732 were classified into 30 categories and used for analysis. "Animal Models," "Rehabilitation," and "Reperfusion Therapy" were identified as the three most prevalent topics. Linear regression models identified "Emboli," "Medullary and Cerebellar Infarcts," and "Glucose Metabolism" as trending topics, whereas "Cerebral Venous Thrombosis," "Statins," and "Intracerebral Hemorrhage" demonstrated a weaker trend.
    CONCLUSIONS: The methodology can assist researchers, funders, and publishers by documenting the evolution and specialization of topics. The findings illustrate the significance of animal models, the expansion of rehabilitation research, and the centrality of reperfusion therapy. Limitations include a five-journal cap and a reliance on high-quality metadata.
    Keywords:  BERTopic; machine learning; natural language processing; stroke; topic modeling
    DOI:  https://doi.org/10.1016/j.jstrokecerebrovasdis.2024.107665
  52. Cureus. 2024 Jan;16(1): e52824
    An Analysis of Medical Student PubMed-Indexed Research Productivity and Factors Associated With Matching at Top-Ranked Ophthalmology Residency Programs.
    Chandruganesh Rasendran, Sanjana Murali, Nithya Kanagasegar, Manasvee Kapadia, Jonathan Lass, Linda Ohsie-Bajor.
      Background Limited information exists regarding the research productivity of matched ophthalmology applicants given that ophthalmology residencies do not participate in the National Residency Match Program. Objectives This study determines the research productivity characteristics of matched ophthalmology applicants and variables associated with matching to higher-tier ophthalmology residency programs. Methods Medical school, matched residency program, and applicant-specific PubMed-indexed research productivity (including consideration for first-author publications, relevance to ophthalmology, and acceptance before application submission date) for 2020-2021 matched ophthalmology applicants were collected from publicly available websites. Statistical analysis was conducted using chi-squared tests and t-tests to compare research productivity between groups (gender, medical school tier, and ophthalmology residency program Doximity rank). Multivariate regression was used to analyze research factors associated with matching at the top 20 Doximity-ranked ophthalmology residency programs. Results Three hundred ninety-three matched ophthalmology applicants for the 2020-2021 academic year were analyzed with an average of 2.4 ± 3.1 (median: 1 {0-3}) publications, 1.0 ± 2.1 (median: 0 {0-1}) ophthalmic publications, 0.8 ± 1.4 (median: 0 {0-1}) first-author publications, and 0.5 ± 1.1 (median: 0 {0-1}) ophthalmic first-author publications. The applicants who matched at the top 20 Doximity-ranked ophthalmology residency programs were more likely to matriculate from the top 40 medical schools (63% versus 22%, p < 0.001), have more first-author publications at the time of application submission (1.1 ± 1.6 versus 0.7 ± 1.3, p = 0.044), and have more projects resulting in publications after submission (2.0 ± 2.5 versus 1.4 ± 2.3, p = 0.048). In multivariate regression, attendance at a top 40 medical school (adjusted odds ratio {aOR} = 6.07, 95% confidence interval {CI}: 3.56-10.5, p < 0.001) was a significant predictor of matching at a top 20 Doximity ophthalmology residency program, and no variables associated with research productivity were significant predictors. Conclusions There has been a consistent increase in research productivity among matched ophthalmology applicants. However, in multivariate analysis, the medical school tier was the only significant variable for matching at top-tier programs. More nuanced studies regarding the effect of research productivity on ophthalmology applicants are needed.
    Keywords:  medical student outcomes; ophthalmology match; ophthalmology residency; pubmed database; sf match
    DOI:  https://doi.org/10.7759/cureus.52824
  53. J Clin Neurosci. 2024 Feb 22. pii: S0967-5868(24)00080-8. [Epub ahead of print]121 129-154
    The state of diversity among consultant neurologists in the United Kingdom.
    Marianna E Kapsetaki.
      Equitable representation is key for successful clinical and research work. Inequalities in gender, skin colour, and education have been found among professionals in many medical, surgical and academic fields, but have not been examined yet in the current UK neurologists' workforce. This cross-sectional study examined whether there are disparities in gender, perceived skin colour, education, academic productivity, and career progression among UK neurologists. The names of consultant neurologists working in the UK anytime between December 2021 and March 2022 were found via an online search. Online data were collected regarding education, research activity, academic productivity, impact and progression. A total of 1010 consultant neurologists were found to be working in the UK. There was predominance of men at consultant level, with a university affiliation, and with a full professor position. All 24 female full professors had white skin colour. There were no skin colour or gender disparities in currently being affiliated with a top university, obtaining a Master's degree, or duration between medical degree obtainment and becoming full professors. However, less black or brown neurologists had obtained a PhD, were consultants, andit took them a longer time from medical school graduation until becoming consultants.Less females were currently affiliated with a university and had obtained their medical degree from a top university. There were also skin colour and gender disparities in bibliometrics. In conclusion, this study revealed that there are gender, skin colour, education, academic productivity, and career progression gaps among UK consultant neurologists, which need to be addressed.
    Keywords:  Bibliometrics; Diversity; Gender; Neurologists; Open science; Scholarly productivity; Skin colour
    DOI:  https://doi.org/10.1016/j.jocn.2024.02.019
  54. Pediatr Dermatol. 2024 Feb 26.
    Pediatric hidradenitis suppurativa publication trends: 2012 to 2022.
    Sarah E Park, Terri Shih, Caitlyn Dagenet, Marcia Hogeling, Meagan Hughes, Justin Gillenwater, Vivian Y Shi, Jennifer L Hsiao.
      There is a paucity of bibliometric data on pediatric-focused hidradenitis suppurativa (HS) publications. To better characterize research trends in pediatric HS and gaps in literature, we systematically searched PubMed between 2012 and 2022 for publications on pediatric HS and collected data on study design, topic, country, and level of evidence. Of 109 articles that met inclusion criteria, less than half (44/109, 40.4%) were high level of evidence studies; the most common study types were case reports/series (41/109, 37.6%) and cross-sectional studies (25/109, 22.9%), and the most common study topics were HS treatments (44/109, 40.4%), comorbidities (20/109, 18.3%), and clinical presentation (14/109, 12.8%). Although there has been expansion of the pediatric HS literature in recent years, our study highlights the need for larger prospective studies and trials to improve our ability to optimally manage pediatric HS patients and identify predictors of disease progression and treatment response.
    Keywords:  bibliometric; hidradenitis suppurativa; pediatric; publication trends
    DOI:  https://doi.org/10.1111/pde.15574
  55. Psychogeriatrics. 2024 Feb 25.
    Analysis of dementia research trends in nursing using text mining approach.
    Eda Atay, Emel Bahadır Yılmaz, Metehan Atay.
      This research aimed to analyze dementia research trends in nursing using a text mining approach. In this study, text mining approach was used to analyze the studies on dementia in the field of nursing around the world. In this study, summaries of all available publications in English between the years 1990-2023 were extracted from the database and transferred to an Excel table by using the 'Nursing' AND 'Dementia' query from the Thomson Reuters-ISI Web of Science database. According to the results of this research, a total of 21 concept groups were identified, four of which were the most important. It was determined that the most frequently used word in all of the studies obtained from the database was 'cost'. In this direction, scientific research on dementia in the field of nursing can be planned by evaluating the most frequently used concepts.
    Keywords:  data mining; dementia; nursing; research trends
    DOI:  https://doi.org/10.1111/psyg.13097
  56. J Craniofac Surg. 2024 Feb 29.
    Clinical Research Fellowship Fosters Mentorship, Teamwork, and Productivity: Our 11-Year Experience With a Craniofacial Research Fellowship.
    Dominic J Romeo, Steven Du, Benjamin B Massenburg, Jinggang J Ng, Meagan Wu, Dillan F Villavisanis, John P Fischer, Jordan W Swanson, Scott P Bartlett, Jesse A Taylor.
       INTRODUCTION: This study describes the development and explores the academic impact of a cleft and craniofacial research fellowship.
    MATERIALS AND METHODS: Research and career outcomes from 3 cleft and craniofacial surgeons, 14 clinical fellows, and 25 research fellows between 2010 and 2023 were examined. Academic productivity was measured by the number of peer-reviewed publications indexed in PubMed and podium presentations at national/international meetings. Residency match statistics were recorded for eligible research fellows.
    RESULTS: Over this 14-year period (11 with research fellows), the team produced 500 publications in 96 peer-reviewed journals, with 153 (31%) in Plastic and Reconstructive Surgery, 117 (23%) in the Journal of Craniofacial Surgery, and 32 (6%) in The Cleft Palate-Craniofacial Journal. Yearly publications increased from 15.3±7.6 per year (before fellowship) to 23.0±5.3 (with 1 fellow) to 38.3±12.9 (2 fellows) to 81.0±5.7 (3 fellows; P<0.001). There was a strong annual linear growth in publications since the beginning the research fellowship position (r=0.88, P<0.001). All (100%) clinical research fellows developed strong relationships with senior surgeons, and all who applied to plastic surgery residency matched a significantly higher success rate than the national average (P<0.05).
    CONCLUSION: Implementing a structured cleft and craniofacial clinical research fellowship was associated with a broad impact across all cleft and craniofacial team members, as reflected by increased academic output and high match rates among fellows. The fellowship also strengthens the talent pipeline into plastic surgery by fostering meaningful mentor/mentee relationships and provides a model that can be adopted in both surgical and nonsurgical fields.
    DOI:  https://doi.org/10.1097/SCS.0000000000009978
  57. Discov Oncol. 2024 Feb 25. 15(1): 50
    Current and future of immunotherapy for thyroid cancer based on bibliometrics and clinical trials.
    Ke Wang, Ying Zhang, Yang Xing, Hong Wang, Minghua He, Rui Guo.
       BACKGROUND: Thyroid cancer is a leading endocrine malignancy, with anaplastic and medullary subtypes posing treatment challenges. Existing therapies have limited efficacy, highlighting a need for innovative approaches.
    METHODS: We analyzed 658 articles and 87 eligible clinical trials using bibliometric tools and database searches, including annual publication and citation trends, were executed using Web of Science, CiteSpace, and VOS Viewer.
    RESULTS: Post-2018, there is a surge in thyroid cancer immunotherapy research, primarily from China and the University of Pisa. Of the 87 trials, 32 were Phase I and 55 were Phase II, mostly exploring combination therapies involving immune checkpoint inhibitors.
    CONCLUSION: The study's dual approach verifies the swift advancement of thyroid cancer immunotherapy from diverse perspectives. Immune checkpoint inhibitors have become the preferred regimen for advanced MTC and ATC in late therapeutic lines. However, since ICB plays a pivotal role in ATC, current clinical trial data show that ATC patients account for more and the curative effect is more accurate. Anticipated future developments are inclined toward combination regimens integrating immunotherapy with chemotherapy or targeted therapies. Emerging approaches, such as bispecific antibodies, cytokine-based therapies, and adoptive cell therapies like CAR-T and TCR-T, are exhibiting considerable potential. Upcoming research is expected to concentrate on refining the tumor immune milieu and discovering novel biomarkers germane to immunotherapeutic interventions.
    Keywords:  Anaplastic thyroid carcinoma (ATC); Clinical Trials; Immune checkpoint inhibitor; Immunotherapy; Medullary thyroid carcinoma (MTC); PD-1/PD-L1; Scientometric analysis; Thyroid cancer
    DOI:  https://doi.org/10.1007/s12672-024-00904-6
  58. Environ Sci Pollut Res Int. 2024 Feb 26.
    What do we know about plastic pollution in Brazilian aquatic ecosystems?
    Leticia Carneiro Ferreira, Juliana Souza Azevedo.
      Due to the increasing use and inadequate disposal of plastic by humans, aquatic environments have become receptacles for pollutants such as plastic. This study aimed to perform an analysis of plastic particles pollution in Brazilian aquatic ecosystems with special attention to inland aquatic environments and fish in order to identify information gaps in this field. Manuscripts published in the last 21 years and indexed in the Web of Science database were consulted. A total of 185 met the proposed inclusion criteria, such as having empirical data, being conducted in Brazil, and dealing with plastic pollution. In general, the number of studies increases over the years, and this increasing number of publications is accompanied by declared financial support; the Southeast and Northeast regions are the regions that publish the most on the topic, with São Paulo, Rio de Janeiro, and Pernambuco being the main states; the main focus of the studies is the detection of plastic particles mainly in biota (51%) and sediment (34%), and the most frequent ecosystem is the marine (89%); regarding the taxa, the majority is about plastic detection in fish (75%). Only 18% of the papers studying fishes consider their bio-ecological data, and only 17% of the manuscripts carried out the chemical characterization of the particles. However, 99% of the papers considered the shape of the plastic particle. We emphasize the need for more research and grants for studies with Brazilian inland aquatic ecosystems on the effects of plastic particle pollution on freshwater fish. Regional and national research funding agencies are very important to encourage an increase in the number of grants and specific calls for studies on plastic pollution and its impact on freshwater biota, considering the different macro-regions in Brazil, especially in the northern region.
    Keywords:  Aquatic pollution; Fish; Literature review; Plastic; Scientometrics
    DOI:  https://doi.org/10.1007/s11356-024-32525-5
  59. Can J Urol. 2024 Feb;31(1): 11777-11783
    Grant funding among underrepresented minority and women urologists at academic institutions.
    Simon White, David Tella, Bahrom Ostad, David Barquin, Caleigh Smith, Rebecca King, Kirsten L Greene, Tracy Downs, Nora G Kern.
       INTRODUCTION: Grant funding to Urology has decreased over the last decade. Documented lack of gender and race diversity at the faculty level raises concerns for funding disparities. This study sought to characterize disparities based upon race and gender in National Institutes of Health (NIH) funding data to Urologic faculty.
    METHODS AND MATERIALS: Data from 145 ACGME accredited Urology residency programs incorporating faculty gender and underrepresented in medicine (URiM) status was utilized. The NIH Research Portfolio Online Report Tool was queried between 1985 and 2023 for grants related to current Urology faculty. URiM status, gender, years of practice, academic rank, and Doximity residency program rank were factors in multivariable analysis.
    RESULTS: A total of 2,131 faculty were included. Three hundred one Urologists received 793 urologic grants for a total of $993,919,052 in funding. By race, grants were awarded to: White 72.9%, Asian 21.8%, Hispanic 3.0%, Black 2.1%. Men received 708 grants (89.3%) worth $917,083,475 total. Women received 85 grants (10.7%) worth $76,835,577 total. Likelihood of being awarded a grant was significantly associated with non-URiM status (p < 0.001) and men (p < 0.0001). On multivariable analysis, Doximity rank (p < 0.001) and academic rank (p < 0.001) were significant predictors of receiving a grant; male gender, URiM status, and years of practice were not. Academic rank was also a significant predictor of number of grants received (p = 0.04) and total funding (p = 0.04); years of practice, Doximity rank, URiM status, and gender were not.
    CONCLUSIONS: NIH grants were more likely awarded to higher ranked faculty from higher Doximity ranked institutions with no differences based on URiM status or gender.
    Keywords:  cultural diversity; educational grants; gender; urology
  60. J Phys Act Health. 2024 Feb 27. 1-11
    An Overview of Physical Activity Research Evolution in Africa: The Global Observatory for Physical Activity-GoPA!
    Adewale L Oyeyemi, Andrea Ramirez Varela, Estelle V Lambert, Eduardo Ribes Kohn, Pedro C Hallal, Michael Pratt.
       OBJECTIVE: To describe the evolution of physical activity (PA) research in Africa, examine income and gender inequalities, and discuss future possibilities.
    METHODS: A secondary analyses of the Global Observatory for Physical Activity data on PA research in Africa (1950-2019).
    RESULTS: We identified 514 PA articles from 47 African countries in the past 70 years. Majority (83.1%) of the articles were published between 2012 and 2019. Fifteen countries had no publications. Six countries (South Africa [n = 156], Nigeria [n = 85], Ethiopia [n = 44], Ghana [n = 41], Kenya [n = 39], and Cameroon [n = 20]) accounted for about 75% of the publications. Most articles were observational (92.4%), single-country studies (78.4%), with male first (58.4%) and last authors (68%), and were classified as surveillance studies (45.1%). Few studies addressed interventions (5.8%) and policy (3.5%) or used device-based PA measurement (14.0%). The number of articles per country was positively related to human population level (r = .552, P = .000) and gross domestic product % spent on research and development (r = .301, P = .040). The publication rate per 100,000 people was positively related with the human development index (r = .349, P = .016) and negatively with the gender inequality index (r = -.360, P = .019).
    CONCLUSIONS: Our results provide an overview and status of PA research in Africa, highlighting country differences and gender inequalities in authorship. The findings may be used to benchmark the evolution of research in the region and to inform areas for improvement. There is an urgent need for more PA interventions and policy studies in Africa.
    Keywords:  active living; gender inequality; low- and middle-income countries; physical inactivity; public health; publication authorship; surveillance
    DOI:  https://doi.org/10.1123/jpah.2023-0455
  61. Cerebrovasc Dis. 2024 Feb 24.
    Sex and gender publications in brain health: a mapping review of the Asia-Pacific region.
    Megan Heffernan, Mark Woodward, Deidre Anne De Silva, Christopher Chen, Craig S Anderson, Christine Kremer, Katie Harris, Else Charlotte Sandset, Maria Teresa Ferretti, Valeria Caso, Cheryl Carcel.
       INTRODUCTION: Reporting of sex and gender analysis in medical research has been shown to improve quality of the science and ensures findings are applicable to women and men. There is conflicting evidence on whether efforts by funding agencies and medical journals to encourage reporting of sex and gender analysis has resulted in tangible improvements. This study mapped the inclusion of sex and gender analysis in stroke and dementia research conducted in the Asia-Pacific region.
    METHODS: A systematic search for Asia-Pacific stroke and dementia research was conducted in PubMed and papers included from the period 2012 to 2022. Eligible studies were reviewed for inclusion of a primary sex or gender focus and categorized by type of sex and gender analysis. Author gender was determined using an algorithm and its associations with inclusion of sex and gender analysis examined.
    RESULTS: Total Asia-Pacific publications increased from 109 in 2012 to 313 in 2022, but the rate of studies with a primary sex or gender focus did not increase significantly (R2 = 0.06, F(1,9) = 0.59, p = 0.46). Australia, China, India, Japan and South Korea produced the most publications over the study period and were the only countries with at least 50 publications. The impact of author gender was mixed, with female first authorship associated with inclusion of sex or gender analysis and last female authorship associated with studies having a primary sex or gender focus.
    CONCLUSIONS: In the Asia-Pacific, brain health research is currently centered around high income countries and efforts are needed to ensure research findings are applicable through out the region. While there was a general increase in brain health publications over the last decade, the rate of sex and gender analysis was unchanged. This demonstrates that even with efforts in some countries in place, there is currently a lack of progress in the Asia-Pacific region to produce more research focusing on sex and gender analysis.
    DOI:  https://doi.org/10.1159/000537946
  62. Heliyon. 2024 Feb 29. 10(4): e26694
    A brief review and scientometric analysis on ensemble learning methods for handling COVID-19.
    Mohammad Javad Shayegan.
      Numerous efforts and research have been conducted worldwide to combat the coronavirus disease 2019 (COVID-19) pandemic. In this regard, some researchers have focused on deep and machine-learning approaches to discover more about this disease. There have been many articles on using ensemble learning methods for COVID-19 detection. Still, there seems to be no scientometric analysis or a brief review of these researches. Hence, a combined method of scientometric analysis and brief review was used to study the published articles that employed an ensemble learning approach to detect COVID-19. This research used both methods to overcome their limitations, leading to enhanced and reliable outcomes. The related articles were retrieved from the Scopus database. Then a two-step procedure was employed. A concise review of the collected articles was conducted. Then they underwent scientometric and bibliometric analyses. The findings revealed that convolutional neural network (CNN) is the mostly employed algorithm, while support vector machine (SVM), random forest, Resnet, DenseNet, and visual geometry group (VGG) were also frequently used. Additionally, China has had a significant presence in the numerous top-ranking categories of this field of research. Both study phases yielded valuable results and rankings.
    Keywords:  COVID-19; Convolutional neural network; Deep learning; Ensemble learning; Ensemble method
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e26694
  63. Surg Open Sci. 2024 Mar;18 62-69
    Are our actions matching our words? A review of trainee ethnic and gender diversity in orthopaedic surgery.
    Rishi Trikha, Logan Laubach, Viraj Sharma, Rachel Thompson, Nicholas Bernthal, Riley J Williams, Kristofer J Jones.
       Background: There is a lack of physician ethnic and gender diversity amongst surgical specialties. This study analyzes the literature that promotes diversity amongst surgical trainees. Specifically, this study sought to answer (i) how the number of publications regarding diversity in orthopaedic surgery compares to other surgical specialties, (ii) how the number of publications amongst all surgical subspecialties trends over time and (iii) which specific topics regarding diversity are discussed in the surgical literature.
    Methods: The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were used to query articles from PubMed, Web of Science, Embase and the Cumulative Index to Nursing and Allied Health Literature. Broad inclusion criteria for both ethnic and gender diversity of any surgical specialty were utilized.
    Results: Our query resulted 1429 publications, of which 408 duplicates were removed, and 701 were excluded on title and abstract screening, leaving 320 to be included. The highest number of related publications was in orthopaedic surgery (n = 73) followed by general surgery (n = 56). Out of 320 total articles, 260 (81.3 %) were published after 2015, and 56 of 73 (76.7 %) orthopaedic-specific articles were published after 2015.
    Conclusion: Orthopaedic surgery published the most about ethnic and gender diversity, however, still remains one of the least diverse surgical specialties. With the recent increase in publications on diversity in surgical training, close attention should be paid to ethnic and gender diversity amongst surgical trainees over the coming years. Should diversity remain stagnant, diversification efforts may need to be restructured to achieve a diverse surgeon workforce.
    Key message: Orthopaedic surgery is the surgical subspecialty that publishes the most about trainee ethnic and gender diversity followed by general surgery. With most of this literature being published over the last eight years, it is imperative to pay close attention to the ethnic and gender landscape of the surgeon workforce over the coming years.
    Keywords:  Ethnic diversity; Gender diversity; Orthopaedic surgery; Trainee diversity
    DOI:  https://doi.org/10.1016/j.sopen.2024.02.002
  64. ACS Nano. 2024 Mar 01.
    Developments and Trends of Nanotechnology Application in Sepsis: A Comprehensive Review Based on Knowledge Visualization Analysis.
    Jiaji Fu, Wentai Cai, Shangwen Pan, Lang Chen, Xiaowei Fang, You Shang, Jiqian Xu.
      Sepsis, a common life-threatening clinical condition, continues to have high morbidity and mortality rates, despite advancements in management. In response, significant research efforts have been directed toward developing effective strategies. Within this scope, nanotechnology has emerged as a particularly promising field, attracting significant interest for its potential to enhance disease diagnosis and treatment. While several reviews have highlighted the use of nanoparticles in sepsis, comprehensive studies that summarize and analyze the hotspots and research trends are lacking. To identify and further promote the development of nanotechnology in sepsis, a bibliometric analysis was conducted on the relevant literature, assessing research trends and hotspots in the application of nanomaterials for sepsis. Next, a comprehensive review of the subjectively recognized research hotspots in sepsis, including nanotechnology-enhanced biosensors and nanoscale imaging for sepsis diagnostics, and nanoplatforms designed for antimicrobial, immunomodulatory, and detoxification strategies in sepsis therapy, is elucidated, while the potential side effects and toxicity risks of these nanomaterials were discussed. Particular attention is given to biomimetic nanoparticles, which mimic the biological functions of source cells like erythrocytes, immune cells, and platelets to evade immune responses and effectively deliver therapeutic agents, demonstrating substantial translational potential. Finally, current challenges and future perspectives of nanotechnology applications in sepsis with a view to maximizing their great potential in the research of translational medicine are also discussed.
    Keywords:  bibliometric analysis; biomedicine; diagnosis; nanomaterials; nanotechnology; sepsis; therapy; toxicity
    DOI:  https://doi.org/10.1021/acsnano.3c10458
  65. Int J Med Inform. 2024 Feb 23. pii: S1386-5056(24)00044-3. [Epub ahead of print]185 105381
    Informing nursing policy: An exploration of digital health research by nurses in England.
    Siobhan O'Connor, Louise Cave, Natasha Philips.
       AIMS: Digital health technologies are designed, implemented, and evaluated to support clinical practice, enable patients to self-manage illness, and further public and global health. Nursing and health policies often emphasise the importance of evidence-based digital health services to deliver better care. However, the contribution nurses make to digital health research in many countries is unknown. Hence, this study aims to examine digital health research conducted by nurses in England.
    DESIGN: A bibliometric analysis.
    METHODS: The CINAHL, MEDLINE, and Scopus databases were searched between 2000 and 2022, and supplemented with a hand search of nurses' research profiles. Results were screened by title, abstract, and full text against eligibility criteria. Data were extracted and bibliometric analysis used to summarise the findings.
    RESULTS: Mental health nurses produced the most digital health research in England, followed by nurses working in community care, with several disciplines underrepresented or missing. Web/online health services or information was the most researched technology, followed by mobile health and telehealth. Nurses based in the south-east and north-west of England produced the most digital health research, with other regions less well represented.
    CONCLUSION: Nurse leaders should support nurses to conduct more digital health research by providing dedicated time, funding, and professional development opportunities, particularly in under researched clinical areas, technologies, and geographic regions to further evidence-based practice and patient care. More digital nursing data is needed to support nurse led research in areas like artificial intelligence and data science. The findings supported the national Philips Ives Review by identifying areas of digital nursing research that need more investment in England.
    Keywords:  Nurses; Nursing; Nursing Informatics; Patients; Research; Technology; Telemedicine; United Kingdom
    DOI:  https://doi.org/10.1016/j.ijmedinf.2024.105381
  66. JMIR Form Res. 2024 Feb 28. 8 e49905
    The Influence of Human Connections and Collaboration on Research Grant Success at Various Career Stages: Regression Analysis.
    Akiko Hashiguchi, Makoto Asashima, Satoru Takahashi.
       BACKGROUND: Documenting the grant acquisition characteristics of a highly selective group of researchers could provide insights into the research and faculty development of talented individuals, and the insights gained to foster such researchers will help university management strengthen their research capacity.
    OBJECTIVE: This study examines the role of human connections in the success of biomedical researchers in Japanese universities.
    METHODS: This study used grant data from the Grants-in-Aid for Scientific Research (GIA) program, the largest competitive research funding program in Japan, to collect information on projects and their implementation systems obtained throughout the participants' careers. Grant success was measured by the number and amounts of the awards obtained while participants occupied the role of principal investigator. Human connections were quantified by the number of projects in which the participants took part as members and were classified by their relationship with the project leader. Data were matched with information on career history, publication performance, and experience of the participants with government-funded programs apart from GIA and were analyzed using univariate and multivariate regression analyses.
    RESULTS: Early-career interpersonal relationships, as measured using the h-index value of the researchers who provided the participants with their initial experience as project members, had a positive effect on grant success. The experience of contributing to prestigious research programs led by top researchers dramatically increased the cumulative amount of GIA awards received by the participants over time. Univariate logistic regression analyses revealed that more interactions with upper-level researchers resulted in fewer acquisitions of large programs (odds ratio [OR] 0.67, 95% CI 0.50-0.89). Collaboration with peers increased the success rate of ≥2 research grants in large programs in situations in which both the participant and project leader were professors (OR 1.16, 95% CI 1.06-1.26). Tracking the process of research development, we found that collaboration during the periods of 10 to 14 years and 15 to 19 years after completing a doctorate degree determined the size of the project that the participant would obtain-interactions with peer researchers and subordinates during the 10- to 14-year postdegree period had positive effects on ≥2 large-program acquisitions (OR 1.51, 95% CI 1.09-2.09 and OR 1.31, 95% CI 1.10-1.57, respectively), whereas interactions with subordinates during the 15- to 19-year postdegree period also had positive effects (OR 1.25, 95% CI 1.25-1.07). Furthermore, relationships that remained narrowly focused resulted in limited grant success for small programs.
    CONCLUSIONS: Human networking is important for improving an individual's ability to obtain external funding. The results emphasize the importance of having a high-h-indexed collaborator to obtain quality information early in one's career; working with diverse, nonsupervisory personnel at the midcareer stage; and engaging in synergistic collaborations upon establishing a research area in which one can take more initiatives.
    Keywords:  biomedical researchers; grant success; human connection; peer researchers; research development; synergistic collaborations
    DOI:  https://doi.org/10.2196/49905
  67. Oral Dis. 2024 Feb 29.
    A scientometric analysis of oral cancer research in South/Southeast Asia and China in oral diseases.
    Wei Liu, Keyan Miao, Yue He.
      
    Keywords:  bibliometrics; oral squamous cell carcinoma; research trends; risk factors; study hotspots
    DOI:  https://doi.org/10.1111/odi.14898
  68. Adv Colloid Interface Sci. 2024 Feb 16. pii: S0001-8686(24)00035-6. [Epub ahead of print]325 103112
    The promise of nanofluids: A bibliometric journey through advanced heat transfer fluids in heat exchanger tubes.
    Hamza Babar, Hongwei Wu, Wenbin Zhang, Tayyab Raza Shah, Daniel McCluskey, Chao Zhou.
      Thermal management is a critical challenge in advanced systems such as electric vehicles (EVs), electronic components, and photoelectric modules. Thermal alleviation is carried out through the cooling systems in which the coolant and the heat exchangers are the key components. The study examines recent literature on nanofluids and heat exchanger tubes along with state-of-the-art concepts being tested for heat transfer intensification. The performance of nanofluids in several common heat transfer tubes' geometries/configurations and the effectiveness of novel heat transfer augmentation mechanisms are presented. Promising results have been reported, showing improved heat transfer parameters with the use of nanofluids and intensification mechanisms like turbulators, fins, grooves, and variations in temperature and flow velocity. These mechanisms enhance dispersion stability, achieve a more uniform temperature distribution, and reduce the boundary layer thickness, resulting in lower tube wall temperatures. Moreover, introducing flow pulsations and magnetic effects further enhances particle mobility and heat exchange. However, there are limitations, such as increased frictional losses and pressure drop due to magnetic effects. The combination of nanofluids, novel heat exchanger tube geometries, and turbulators holds great promise for highly efficient cooling systems in the future. The study also presents a bibliometric analysis that offers valuable insights into the impact and visibility of research in the integration of nanofluids into heat transfer systems. These insights aid in identifying emerging trends and advancing the field towards more efficient and compact systems, paving the way for future advancements.
    Keywords:  Cooling systems; Heat exchanger tubes; Heat transfer intensification; Nanofluids; Thermal management
    DOI:  https://doi.org/10.1016/j.cis.2024.103112
  69. BMC Health Serv Res. 2024 Mar 01. 24(1): 263
    What factors are associated with the research productivity of primary care researchers in Canada? A qualitative study.
    Monica Aggarwal, Brian Hutchison, Sabrina T Wong, Alan Katz, Steve Slade, Deirdre Snelgrove.
       BACKGROUND: Research evidence to inform primary care policy and practice is essential for building high-performing primary care systems. Nevertheless, research output relating to primary care remains low worldwide. This study describes the factors associated with the research productivity of primary care researchers.
    METHODS: A qualitative, descriptive key informant study approach was used to conduct semi-structured interviews with twenty-three primary care researchers across Canada. Qualitative data were analyzed using reflexive thematic analysis.
    RESULTS: Twenty-three primary care researchers participated in the study. An interplay of personal (psychological characteristics, gender, race, parenthood, education, spousal occupation, and support), professional (mentorship before appointment, national collaborations, type of research, career length), institutional (leadership, culture, resources, protected time, mentorship, type), and system (funding, systematic bias, environment, international collaborations, research data infrastructure) factors were perceived to be associated with research productivity. Research institutes and mentors facilitated collaborations, and mentors and type of research enabled funding success. Jurisdictions with fewer primary care researchers had more national collaborations but fewer funding opportunities. The combination of institutional, professional, and system factors were barriers to the research productivity of female and/or racialized researchers.
    CONCLUSIONS: This study illuminates the intersecting and multifaceted influences on the research productivity of primary care researchers. By exploring individual, professional, institutional, and systemic factors, we underscore the pivotal role of diverse elements in shaping RP. Understanding these intricate influencers is imperative for tailored, evidence-based interventions and policies at the level of academic institutions and funding agencies to optimize resources, promote fair evaluation metrics, and cultivate inclusive environments conducive to diverse research pursuits within the PC discipline in Canada.
    Keywords:  Individual; Institution; Primary care; Professional; Qualitative study; Research productivity; System
    DOI:  https://doi.org/10.1186/s12913-024-10644-6
  70. Environ Sci Pollut Res Int. 2024 Mar 02.
    Bibliometric analysis of Advanced Oxidation Processes studies with a focus on Life Cycle Assessment and Costs.
    Isadora Luiza Clímaco Cunha, Pedro Gerber Machado, Celma de Oliveira Ribeiro, Luiz Kulay.
      Advanced oxidation processes (AOPs) are wastewater treatment technologies that stand out for their ability to degrade Contaminants of Emerging Concern (CECs). The literature has extensively investigated these removal processes for different aqueous matrices. Once technically mature, some of these systems have become accredited to be applied on a large scale, and therefore, their systemic performances in the environmental and cost spheres have also become essential requirements. This study proposed corroborating this trend, analyzing the available literature on the subject to verify how experts in the AOP area investigated this integration during 2015-2023. For this purpose, a sample of publications was treated by applying the Systematic Review (SR) methodology. This resulted in an extract of 83 studies that adopted life-cycle logic to estimate environmental impacts and process costs or evaluated them as complementary to the technical dimension of each treatment technology. This analysis found that both dimensions can be used for selecting or sizing AOPs at the design scale. However, the appropriate choice of the impact categories for the environmental assessment and establishing a methodology for cost analysis can make the approach still more effective. In addition, a staggering number of processes would broaden the reality and applicability of the estimates, and adopting multicriteria analysis methodologies could address essential aspects of decision-making processes during the design of the arrangements. By meeting the original purposes, the study broadened the requirements for designing AOPs and disseminating their use in mitigating the discharge of CECs.
    Keywords:  Advanced Oxidation Processes; Contaminants of Emerging Concern; Economic analysis; Life Cycle Assessment; State-of-the-art review; Wastewater Treatment
    DOI:  https://doi.org/10.1007/s11356-024-32558-w
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