bims-evares Biomed News
on Evaluation of research
Issue of 2024–12–22
seventy papers selected by
Thomas Krichel, Open Library Society
  1. Research trends and frontiers on risk factors of urinary stones: a bibliometric analysis from 2010 to 2023.
  2. Clinical Neurology Research Output From Türkiye: A Bibliometric Analysis.
  3. Bibliometric analysis of global research on vitamins and cancer between 2003 and 2022.
  4. Renal cell carcinoma and macrophage research: A bibliometric analysis (2004-2023).
  5. Research of digital management on sport: An analysis of bibliometrics using CiteSpace Software.
  6. Progress and Frontiers of Research on Dexmedetomidine in Perioperative Medicine: A Bibliometric Analysis.
  7. Global research trends in therapeutic drug monitoring of antimicrobials from 2000 to 2023: a bibliometric analysis.
  8. Non-Pharmacological Therapies for Post-Stroke Spastic Paralysis: A Bibliometric Analysis of Global Research from 2000 to 2024.
  9. Research trends of artificial intelligence and radiomics in lung cancer: a bibliometric analysis.
  10. Research trends and hotspots in gastric carcinoma associated exosome: a bibliometric analysis.
  11. A bibliometric analysis of root canal irrigation: From laboratory to clinical practice.
  12. Cross-border collaboration, communication, and research frontiers on biologics in chronic rhinosinusitis from 2004 to 2023.
  13. Bibliometric analysis of rehabilitation in Alzheimer's disease (2000-2023): trends, hotspots and prospects.
  14. Unveiling the complementariness of robotic tablet dispensing machines for elderly care: A bibliometric data analysis.
  15. Developmental trends and knowledge frameworks in the application of radiomics in prostate cancer: a bibliometric analysis from 2000 to 2024.
  16. A bibliometric analysis of vaccination against atherosclerosis.
  17. Analysis of tumor treatment under interventional ultrasound through structural and temporal dynamics: a bibliometric visualization.
  18. Human-Computer Interaction in Healthcare: A Bibliometric Analysis with CiteSpace.
  19. Visual analysis of research trends and hotspots in wearable electronic devices in the medical field: A bibliometric study.
  20. Research Trends and Hotspots on Asthma and Depression: A Bibliometric Analysis.
  21. Bibliometric and visual study of narcolepsy from 2000 to 2023.
  22. Global research trends in the relationship between influenza and CD4+ T/CD8+ T cells: A bibliometric analysis.
  23. Bibliometric and visual analyses of vaccine literacy research from 1982 to 2023.
  24. Global research trends in the teacher evaluation of medical college: A bibliometric and visualized study.
  25. Bibliometric Analysis of Comprehensive Geriatric Assessment from 2004 to 2023.
  26. Top 100 Most-Cited Articles on Difficult Airway Management From 2011 to 2022: A Bibliometric Analysis.
  27. Research Hotspots and Trends of NK Cell Immunotherapy for Acute Myeloid Leukemia: A Bibliometric Analysis From 2000 to 2023.
  28. Bibliometric analysis and visualization of global research trends in primary thyroid lymphoma via CiteSpace.
  29. Antiangiogenic therapy exerts antitumor effects by altering the tumor microenvironment: bibliometric analysis.
  30. Research on rheumatic heart disease from 2013 to early 2024: a bibliometric analysis.
  31. Hotspots and development trends of gut microbiota in atopic dermatitis: A bibliometric analysis from 1988 to 2024.
  32. Low Middle Income Countries and Academic Productivity of Neurosurgery: A Quantitative Analysis From Pakistan.
  33. Research trends and key contributors in studies on influenza vaccines for children: A 20-year bibliometric analysis.
  34. Bibliometric analysis of research developments in oral and maxillofacial neuralgia from 2004 to 2023.
  35. N6-methyladenosine (m6A) modification in inflammation: a bibliometric analysis and literature review.
  36. A bibliometric analysis of studies on environmental enrichment spanning 1967-2024: patterns and trends over the years.
  37. Cancer phenomics research hotspots and development trends: a bibliometric analysis from 2000 to 2023.
  38. The application of artificial intelligence in diagnosis of Alzheimer's disease: a bibliometric analysis.
  39. Advances in applying somatosensory interaction technology in geriatric care: A bibliometric analysis.
  40. Deciphering the past status and future tendency: a comprehensive scientometric study on developmental dysplasia of the hip.
  41. Trends of mapping knowledge structure and themes of cancer sonodynamic therapy: a text-mining study.
  42. Breaking down the relationship between disruption scores and citation counts.
  43. A bibliometric analysis of preoperative fasting and fluid management: Trends and advances from 2004 to 2023.
  44. Government document citations in top nursing journals: A bibliometric analysis.
  45. Citation patterns of Cochrane Reviews and other systematic reviews: a bibliometric analysis.
  46. Treated greywater as a novel water resource: The perspective of greywater treatment for reuse from a bibliometric analysis.
  47. Research trends on AI in breast cancer diagnosis, and treatment over two decades.
  48. Corrigendum: A bibliometric analysis of interstitial cells of Cajal research.
  49. Gender, Race, and Regional Disparities in Leading Authorships of Gastroenterology and Hepatology Randomized Controlled Trials.
  50. Research Progress and Hotspots Analysis of Apoplastic Barriers in the Roots of Plants Based on Bibliometrics from 2003 to 2023.
  51. Global Research on Cyberchondria: Scientometric and Visual Analysis From 2003 to 2022.
  52. Luteolin: A Comprehensive and Visualized Analysis of Research Hotspots and its Antitumor Mechanisms.
  53. Artificial intelligence applications in ophthalmic optical coherence tomography: a 12-year bibliometric analysis.
  54. The training in thoracoscopic surgery: a comparative study and bibliometric analysis.
  55. High impact works on stem cell transplantation in intervertebral disc degeneration.
  56. Bibliometric analysis of research trends in agricultural soil organic carbon components from 2000 to 2023.
  57. Probiotic effects on skin health: comprehensive visual analysis and perspectives.
  58. Environmental Indicator Plants in Mountain Forests: A Review.
  59. Evolution of scientific productivity in dentistry: tracking postgraduate publications at a Peruvian university.
  60. Erratum: The quality of life of patients with chronic obstructive pulmonary disease: a bibliometric analysis.
  61. Artificial intelligence in surgery: evolution, trends, and future directions.
  62. Laboratory biosafety: A visual analysis in the web of science database from 2000 to 2022: A review.
  63. Retraction of biomedical publications with Tunisian affiliation: causes, characteristics, and legislation regarding breaches of scientific integrity.
  64. Scientometrics Analysis of Global Researches on Anemia.
  65. The only constant in life is change: Summary of the last 4 years of Advances in Clinical and Experimental Medicine.
  66. Relative Citation Ratio Among Pediatric Orthopaedic Surgeons: Examining the Factors Associated With Higher Scores.
  67. Scientific, bibliometric and biographical analysis of 71 Jewish and dissident pharmacologists persecuted in Germany between 1933 and 1945.
  68. Challenges and Progress in Neurosurgery: A Comprehensive Assessment of the Landscape in Nepal.
  69. Contribution of a special issue on Antarctic research to the AABC impact factor.
  70. Examining Gender Representation in US News and World Report Top 25 Urology Departments: Female Faculty Hold Lower Professorial Levels and Publication Rates Than Male Counterparts.
  1. Ren Fail. 2024 Dec;46(2): 2440513
    Research trends and frontiers on risk factors of urinary stones: a bibliometric analysis from 2010 to 2023.
    Yongfu Zhong, Qing Zeng, Jiayou Yi, Tao Long, Juanwen Peng, Li Zhong.
       BACKGROUND AND OBJECTIVE: The occurrence of urinary stone disease (USD) is associated with several factors. However, no conclusive results have been reached regarding the treatment of USD risk factors. This study conducted a detailed bibliometric analysis of USD risk factors to determine research hotspots and provide future development directions.
    METHODS: Articles and reviews on the USD risk factors published between 2010 and 2023 were retrieved from the Web of Science Core Collection. Co-occurrence and collaboration analyses of countries, institutions, authors, journals, references, and keywords were conducted using CiteSpace, VOSviewer, and R-Bibliometrix.
    RESULTS: A total of 436 articles on USD risk factors were included in the study. China and the United States have emerged as the leading countries in this field, with the Mayo Clinic having the highest amount of publication output. Among all the authors, Ferraro PM had the highest number of publications, while Taylor EN was the highly cited author. The journal with the highest number of publications was UROLITHIASIS. Scales reported the reference with the highest burst strength. The current citation themes in research on USD risk factors were 'multifaceted relationship' and 'kidney stone disease recurrence'. 'Medical-management' was identified as a major keyword, indicating future research hotspots.
    CONCLUSION: This study employed bibliometric methods to conduct a comprehensive visual analysis of USD risk factors to show publication trends and popular topics in this area over the past decade. The results provide a valuable reference for future research on the risk factors of USD.
    Keywords:  CiteSpace; R-Bibliometrix; USD; VOSviewer; bibliometrics; risk factors
    DOI:  https://doi.org/10.1080/0886022X.2024.2440513
  2. Noro Psikiyatr Ars. 2024 ;61(4): 313-323
    Clinical Neurology Research Output From Türkiye: A Bibliometric Analysis.
    Seden Demirci, Fatma Yardibi.
       Introduction: Bibliometric analysis is a comprehensive method used to investigate the academic impact and characteristics of publications in a research field. It has been widely used in various fields of medicine. However, bibliometric analysis of publications in the field of clinical neurology from Türkiye has not yet been evaluated. In this study, we aimed to analyze the publications in the field of clinical neurology in the last decade from Türkiye using the bibliometric method and network analysis and to determine research trends and key issues.
    Methods: We carried out a search of the Web of Science Core Collection database for articles. CiteSpace Advances 6.1. R 1 and VOSviewer (version 1.6.9) were used for bibliometric analyses and visualization.
    Results: The research data consisted of 8404 articles in the category of the clinical neurology from Türkiye between 2012 and 2022. The number of publications rose over time, with a mean annual growth rate of 6%. From the document co-citation analysis, chronic migraine and mental health clusters were active current areas. From the keywords analysis, endovascular treatment, depression, oxidative stress, Parkinson's disease, epilepsy, multiple sclerosis, and ischemic stroke were active clusters. Analysis of the authors showed that the most active authors were Betul Baykan, Cavit Boz, and Erdem Tuzun, and MS was the most active topic in this area and recent trend.
    Conclusions: Clinical neurology is a rapidly expanding research area and attracting more and more attention from the authors. Our study can provide researchers who study the clinical neurology with valuable information on the current status and trends in this field and to facilitate for future studies.
    Keywords:  Bibliometric analysis; Türkiye; VOSviewer; citespace; clinical neurology; research output
    DOI:  https://doi.org/10.29399/npa.28462
  3. Medicine (Baltimore). 2024 Dec 13. 103(50): e37108
    Bibliometric analysis of global research on vitamins and cancer between 2003 and 2022.
    Wen Wang, Xiangming Ye, Sisi Wang.
       BACKGROUND: Vitamins are essential nutrients that play an indispensable role in maintaining the vital functions of the human body. A growing number of studies have shown a link between vitamins and cancer. However, there is no systematic review and bibliometric analysis in this field. This study aims to summarize the hotspots and emerging research topics in this field of vitamins and cancer research.
    METHODS: Articles on the topic of vitamins and cancer published between 2003 and 2022 were retrieved from the Web of Science core collection database (WOSCC) on May 1, 2023. Subsequently, we conducted VOSviewer and CiteSpace to examine the annual output distribution, countries/regions, institutions, journals, authors, co-cited references, and keywords.
    RESULTS: A total of 3166 publications were extracted using a timespan of 2003 to 2022. The number of publications has grown rapidly over the past 20 years. Most publications were from the United States; Harvard University was the most active institutions; Giovannucci stood out among authors with the highest number of publications, citations and H-index; Cancer Epidem Biomar published the most papers in this field; the highest cited reference was published in Nat Rev Cancer, authored by Feldman in 2014. Breast cancer was the most common type of cancer, while vitamin D was a research hotspot in this field. Oxidative stress may be the primary anticancer mechanism of vitamins, while also involving epithelial-mesenchymal transition, apoptosis, polymorphism, and calcium metabolism. "nanoparticle" may be the new focus of attention in the next few years.
    CONCLUSION: This study presented an overview of the major research directions of vitamins and cancer by bibliometric methods over the past 2 decades. The results could reveal the research trends and the hotspots in the field and provide helpful information for clinical treatments of cancer.
    DOI:  https://doi.org/10.1097/MD.0000000000037108
  4. Medicine (Baltimore). 2024 Dec 13. 103(50): e40954
    Renal cell carcinoma and macrophage research: A bibliometric analysis (2004-2023).
    Dingtian Qi, Haoxun Zhang, Feng Xiong, Guoling Zhang, Boju Tao, Chunyang Wang.
      To analyze hotspots and trends in renal cell carcinoma (RCC)-macrophage research using bibliometric analysis, although numerous studies on macrophages in RCC have been recently reported, understanding the progressive trends in this field remains challenging. Publications focused on macrophages in RCC were extracted from the Web of Science Core Collection. VOSviewer, Citespace, and Bibliometrics online platforms were used to visualize hot topics and global trends in RCC-macrophage research. In total, 778 papers were collected. China produced the most articles; however, the United States accounted for the largest number of citations. Oncology journals published the most articles, and these were cited most frequently. Based on keyword analysis, "prognosis," "immunotherapy," "tumor microenvironment," and "immune infiltration" represented the primary research hotspots. In summary, RCC-macrophage studies have emerged as a key research focus; particularly, incorporating multiomics data and applying artificial intelligence for predictive modeling have demonstrated significant potential. Our study suggests that the resistance mechanism of immune checkpoint inhibitors and the interaction between macrophages and immune checkpoint inhibitors will be pivotal areas for future research.
    DOI:  https://doi.org/10.1097/MD.0000000000040954
  5. Medicine (Baltimore). 2024 Dec 13. 103(50): e40872
    Research of digital management on sport: An analysis of bibliometrics using CiteSpace Software.
    Gang Xu, Qian Yang, Qiang Li, Hongli Yu.
      Digital management on sport (DMS) has become a hot topic around sports management. However, a more comprehensive and in-depth investigation into the structure and progression of this field is necessary. We used CiteSpace software to conduct a bibliometric analysis, revealing dynamic patterns in the evolution of co-citation, collaboration, and keyword co-occurrence within this field. Data gathers from the Web of Science Core Collection, which includes Social Sciences Citation Index (SSCI), Arts & Humanities Citation Index (A&HCI), Emerging Sources Citation Index (ESCI) and Science Citation Index Expanded (SCI-EXPANDED), and SCOPUS. Published works in this field have shown a consistent upward trend since 2013. England institutions are leading the way in cooperation, while the US is the most collaborative region with different priorities for collaboration in various topics. The most influential author is the one who receives the most citations, but unfortunately, the most frequently co-cited author shows "ANONYMOUS." Highly cited journals typically exert a substantial influence. Additionally, further study is expected to concentrate on efficacy and validation. Since 2018, the growth in publications on DMS reflects increasing academic interest. Australia's institutions lead in collaboration, though international cooperation is limited. High co-citation authors hold significant influence and research focuses on management, social media, and physical activity.
    DOI:  https://doi.org/10.1097/MD.0000000000040872
  6. Drug Des Devel Ther. 2024 ;18 6017-6029
    Progress and Frontiers of Research on Dexmedetomidine in Perioperative Medicine: A Bibliometric Analysis.
    Teng Zheng, Zhi Pei, Xiaojing Huang.
       Background: Dexmedetomidine has received increasing attention for its sedative, analgesic, anxiolytic, anti-inflammatory and anti-stress effects in perioperative medicine. Numerous studies have been carried out to explore its influence on perioperative patients.
    Objective: This study aimed to identify the most influential literature, trends and hotspots in dexmedetomidine research by bibliometric analysis.
    Methods: Articles and reviews related to dexmedetomidine in perioperative medicine were collected from Web of Science Core Collection. VOSviewer and Citespace software were used for bibliometric analysis and data visualization.
    Results: A total of 1652 suitable publications were extracted from the database for analysis, including 1,497 articles and 155 reviews. The number of publications in the field of dexmedetomidine research has increased markedly since 2013, with China being the major contributor, followed by United States. BMC Anesthesiology published the highest number of papers on this topic. Anesthesiology ranked first in terms of average citations per paper and co-citation journal. Ji Fuhai was the most prolific author, and Ma Daqing was the most cited authors. The main hotspots during this period were "elderly patients", "postoperative cognitive dysfunction", "injury" and "risk factors".
    Conclusion: This study presents an overview of the development related to dexmedetomidine in perioperative medicine using bibliometric analysis. Dexmedetomidine research is thriving and expanding rapidly around the world. The effect of dexmedetomidine on cognitive function has been the latest research hotspot. To advance research in this field, more rigorous and scientific multi-center studies should be designed and further cooperation and academic exchange should be strengthened.
    Keywords:  anesthesia; bibliometrics; dexmedetomidine; perioperative medicine
    DOI:  https://doi.org/10.2147/DDDT.S471602
  7. Front Pharmacol. 2024 ;15 1474878
    Global research trends in therapeutic drug monitoring of antimicrobials from 2000 to 2023: a bibliometric analysis.
    Hao Li, Manxue Jiang, Lingti Kong.
       Objective: The practice of therapeutic drug monitoring (TDM) is widely used for maximizing the clinical efficacy of antimicrobials. However, a systematic bibliometric analysis providing an overview of this field is lacking at present. The aim of the current study was to identify hotspots and trends in antimicrobial TDM, highlight collaborations and influences among countries, institutions, and journals, and assess the knowledge base for further development of clinical research.
    Research Design and Methods: Articles and reviews related to TDM of antimicrobials from the Web of Science Core Collection were collected. CiteSpace and VOSviewer, two visualization tools, were utilized to graphically assess the key elements within this domain, including mapping of countries and regions, institutions, keywords, and references associated with the field of antimicrobial TDM. Through this approach, we were able to successfully provide a comprehensive visual overview of the research landscape, highlighting the significant players and thematic trends in the literature.
    Results: From 2000 to 2023, a total of 17,236 authors from 4,112 institutions in 112 countries/regions published 3,710 papers in 819 academic journals. The United States had the highest number of publications, with University of Queensland identified as the most active institution. The journal with the greatest number of publications was Therapeutic Drug Monitoring, whereas Antimicrobial Agents and Chemotherapy was the most co-cited journal. Current research focuses on pharmacokinetics, pharmacodynamics, vancomycin, posaconazole, invasive fungal infection and critically ill patients. Promising hotspots for future research include vancomycin, voriconazole, meropenem, isavuconazole, posaconazole, and teicoplanin. Moreover, vancomycin and critically ill patients remain a hot topic of future research.
    Conclusion: Using bibliometric and visualization methods, the research hotspots of antimicrobial drugs in TDM were analyzed. The continued increase in the number of annual publications demonstrates the vital significance of TDM for antimicrobials. Data from this study provide a valuable reference for future research trends in TDM of antimicrobial agents.
    Keywords:  VOSviewer; antimicrobial; bibliometrics; citespace; therapeutic drug monitoring
    DOI:  https://doi.org/10.3389/fphar.2024.1474878
  8. J Multidiscip Healthc. 2024 ;17 5949-5965
    Non-Pharmacological Therapies for Post-Stroke Spastic Paralysis: A Bibliometric Analysis of Global Research from 2000 to 2024.
    Ziyi Zhang, Lili Yin, Jingjie Huang, Qiuxuan Wang, Shanshan Sun, Shuoshuo Tan.
       Objective: This study aims to explore the research landscape, hot topics, and future trends of non-pharmacological therapies for post-stroke spastic paralysis globally from 2000 to 2024 through a bibliometric analysis.
    Methods: We conducted a search in the Web of Science Core Collection database to analyze literature related to non-pharmacological therapies for post-stroke spastic paralysis published between 2000 and 2024. Tools including CiteSpace, VOSviewer, Bibliometrix, Scimago, and R language were used to identify and analyze countries, institutions, journals, references, keywords, as well as the most commonly used therapies and acupuncture points. The results were presented in the form of knowledge maps.
    Results: The bibliometric analysis identified a total of 297 publications. Over the study period, the number of publications showed an overall upward trend. China had the highest number of publications. The journal *Archives of Physical Medicine and Rehabilitation* published the most articles. The most frequently occurring keywords were "stroke", "reliability", and "muscle spasticity." The most commonly used therapy was "acupuncture.".
    Conclusion: From 2000 to 2024, non-pharmacological therapies have shown positive effects in improving post-stroke spastic paralysis; however, more rigorously designed large-scale, high-quality randomized controlled trials are needed to confirm their long-term efficacy and mechanisms. Moving forward, international and domestic research institutions should strengthen collaboration to produce more impactful research and further explore individualized, precision rehabilitation treatment plans.
    Keywords:  bibliometric analysis; global trends; non-pharmacological; spasticity; stroke
    DOI:  https://doi.org/10.2147/JMDH.S507752
  9. Quant Imaging Med Surg. 2024 Dec 05. 14(12): 8771-8784
    Research trends of artificial intelligence and radiomics in lung cancer: a bibliometric analysis.
    Yufei Xia, Shupei Zhong, Xinjing Lou, Meiqi Hua, Linyu Wu, Chen Gao.
       Background: Extensive research on the application of artificial intelligence (AI) and radiomics in lung cancer has been published in recent years; however, it is necessary to identify the current status, hotspots, and trends in the field. Thus, this study conducted a bibliometric analysis of relevant studies to investigate the application of AI and radiomics in lung cancer.
    Methods: Related publications were retrieved from the Web of Science Core Collection (WoSCC). CiteSpace generated the associated co-occurrence network maps in terms of institutions, authors, and keywords. Bibliometrix was used to perform a bibliometric analysis of relevant countries/regions and journals. In addition, the collected information was used to generate figures using R.
    Results: A total of 2,989 publications were included in this study, of which 2,804 (93.8%) were articles and 185 (6.2%) were reviews. In 2016, there was a rapid increase in the number of publications in this field. Most of the research originated from China (n=1,365, 45.7%). While Fudan University (n=109, 3.6%) attracted the greatest attention among all institutions. In terms of the authors, Gillies (28 publications, 0.9%) published the greatest number of articles. In terms of the journals, Frontiers in Oncology (n=177, 5.9%) and Radiology (5,152 citations) had the greatest number of publications and influence, respectively. The main keywords identified were "lung cancer", "deep learning", "classification", "computed tomography", and "features". Burst detection suggested that "texture", "image classification", and "false positive reduction" have recently appeared at the frontier of research.
    Conclusions: This study used bibliometric methods to analyze the relevant literature to discuss the current research hotspots and future trends in the application of AI and radiomics in lung cancer. This information may help relevant researchers to shape the direction of future studies, such as innovations in AI techniques standardized feature extraction, and extend understandings of epidermal growth factor receptor mutations.
    Keywords:  Bibliometrics; artificial intelligence (AI); deep learning (DL); lung neoplasms; radiomics
    DOI:  https://doi.org/10.21037/qims-24-1316
  10. Front Oncol. 2024 ;14 1457346
    Research trends and hotspots in gastric carcinoma associated exosome: a bibliometric analysis.
    Chunqiu Liu, Honglei Guo, Fangzhou Jin.
       Background: Stomach cancer is considered the fifth most common cancer worldwide. This study utilized bibliometric analysis to construct a visualization map of the relationship between stomach cancer and exosomes, aiming to reveal research trends and emerging themes, and provide direction for future research.
    Method: Retrieve relevant literature on gastric cancer exosomes in the Web of Science Core Collection (WoSCC) over the past 25 years according to search criteria, and conduct bibliometric and visualization analysis using bibliometric software VOSviewer and CiteSpace.
    Results: This study included a total of 727 articles, with an overall increasing trend in annual publication output. There were 68 countries involved, with China having the largest number of publications followed by the United States. A total of 957 research institutions were involved, with most of the top 10 institutions in terms of publication output being universities in China. The top 5 journals are Molecular Cancer, Cell death & disease, Cancers, International journal of molecular sciences, and Frontiers in oncology. A total of 4529 authors were involved, with 5 authors having a publication output of no less than 13 articles. A total of 35516 references were cited, with a total number of citations. The top publication is "Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells".
    Conclusion: Over the past 25 years, researchers have been dedicated to studying the field of exosomes related to gastric cancer, and research in this area is currently progressing steadily. Based on previous studies, exosomes in gastric adenocarcinoma serve as biomarkers, potential therapeutic targets, and post-resistance treatment, which represents current hotspots and emerging frontiers in research.
    Keywords:  bibliometric analysis; biomarkers; exosome; gastric cancer; tumor suppressor
    DOI:  https://doi.org/10.3389/fonc.2024.1457346
  11. Aust Endod J. 2024 Dec 15.
    A bibliometric analysis of root canal irrigation: From laboratory to clinical practice.
    Yudi Deng, Jinglan Zhang, Xinran Wang, Lei Yang, Qiang He, Dingming Huang, Xuelian Tan.
      The study aims to conduct a bibliometric analysis on root canal irrigation to elucidate the development of this domain and pose the future research trends. Of 6722 articles retrieved from Clarivate Analytics' Web of Science Core Collection and PubMed, 6650 publications were included for bibliometric analysis. Irrigation field had received emerging attention for the last half century, peaking at 399 in 2022. The United States was revealed as the most influential contributor, with Journal of Endodontics representing the most voluminous resource. Franklin R Tay was regarded as the most productive author, while Siqueira, Jose. F. was the most prominent. Both keywords cluster analysis and burst analysis revealed the main research branch fields were irrigation protocols. Within this branch, the discussion of irrigants (with a frequency of 1135) ranked first. This bibliometric study revealed the research hotspot of irrigants, while suggesting the future directions of irrigants' creations and micro-level mechanism elucidation.
    Keywords:  bibliometrics; endodontics; irrigation; root canal irrigants; root canal therapy
    DOI:  https://doi.org/10.1111/aej.12909
  12. Front Big Data. 2024 ;7 1428074
    Cross-border collaboration, communication, and research frontiers on biologics in chronic rhinosinusitis from 2004 to 2023.
    Guan-Jiang Huang, Zhi-Jun Fan, Biao-Qing Lu.
       Objective: Biologics are considered as a promising novel treatment option for patients with chronic rhinosinusitis who failed with the standard of care (medical therapy and surgical interventions). This bibliometric analysis was performed to explore cross-border collaboration, communication, and research frontiers on biologics in chronic rhinosinusitis.
    Methods: Original research publications on biologics in chronic rhinosinusitis were retrieved from the Science Citation Index-Expanded (SCI-E) database in the Web of Science Core Collection between 2004 and 2023. Using CiteSpace and R software, the country/region, author, institution, journal, reference, and keywords were extracted to analyze the research focus and global trends in this field.
    Results: Research articles exhibited a consistent rising trend from 2004 to 2023, especially the period between 2020 and 2023. Most articles were published by authors from the USA. The USA was the most cited country, enjoying the most active cooperation with other countries/regions. Bachert C owned the most publications and collaborations. Ghent University and Karolinska Institute had the most collaborations with other institutions. Journal of Allergy and Clinical Immunology and Allergy published the most articles and were the most co-cited journals. Research frontiers on biologics in chronic rhinosinusitis would focus on efficacy, quality of life, safety, children, management, etc.
    Conclusions: This bibliometric analysis displayed the overall situation and global trend on biologics in chronic rhinosinusitis. The visualization analysis of publications could assist researchers rapidly in understanding the hotspots and trends. Further research is warranted to determine the long-term effects and side effects of biologics in chronic rhinosinusitis.
    Keywords:  bibliometric analysis; biologics; chronic rhinosinusitis; collaboration; frontier
    DOI:  https://doi.org/10.3389/fdata.2024.1428074
  13. Front Aging Neurosci. 2024 ;16 1457982
    Bibliometric analysis of rehabilitation in Alzheimer's disease (2000-2023): trends, hotspots and prospects.
    Peng Jun, Hao Chengye, Wan Hui.
       Background: Alzheimer's disease (AD) is a complex neurodegenerative disease that leads to insidious deterioration of brain functions and is considered the sixth leading cause of death in the world. Multiple studies have shown that rehabilitation therapy is becoming an important field of AD research in recent years.
    Objective: We opted for bibliometric analysis to comprehensively summarize the advancements in the study of AD rehabilitation treatment, aiming to provide researchers with current trends and future research directions.
    Methods: All articles and reviews pertaining to rehabilitation treatment in Alzheimer's disease from 2000 to 2023 were downloaded through Web of Science Core Collection. The results were subjected to bibliometric analysis using Microsoft Excel (2019 version), CiteSpace (6.3 R1 Advanced) and VOSviewer 1.6.20.
    Results: Overall, 1,284 publications were included. The number of publications was increasing yearly. The United States has published the most publications. University of Toronto has published the most papers of all institutions. NEUROPSYCHOLOGICAL REHABILITATION and ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION were the journals with the most studies and the most commonly cited, respectively. Clare L is the author with the highest productivity and co-citation. After analysis, the most common keywords are mild cognitive impairment, cognitive, impairment memory and executive function indicates that cognitive impairment is the main focus of research. Transcranial magnetic stimulation, cognitive rehabilitation, and physical activity/exercise are the hotspots of research at the present stage and are likely to continue.
    Conclusion: Distinguishing non pharmacological treatments at different stages of development is a research hotspot in AD rehabilitation; Sports intervention, brain functional imaging techniques represented by brain functional connectivity, virtual reality, and quality of life are research directions that need attention.
    Keywords:  Alzheimer’s disease; CiteSpace; VOSviewer; bibliometrics; rehabilitation
    DOI:  https://doi.org/10.3389/fnagi.2024.1457982
  14. Explor Res Clin Soc Pharm. 2025 Mar;17 100545
    Unveiling the complementariness of robotic tablet dispensing machines for elderly care: A bibliometric data analysis.
    Sunday Adewale Olaleye, Olaleye Esther Olubunmi, Berhanemeskel Weldegerima Atsbeha, Mulugeta Negash Wodaje.
      This study conducts a bibliometric analysis of academic papers and conference proceedings related to tablet dispensers, medicine dispensers, and pill dispensers within the framework of Sustainable Development Goal 03: Good Health and Well-Being. The analysis spans literature published between 1997 and 2023. Utilizing the Web of Science database, the study employs keywords such as "tablet dispenser," "medicine dispenser," and "pill dispenser" to gather relevant English-language papers classified as Proceeding Papers or Articles. The inclusion and exclusion criteria filtered 79 initial records down to 40, focusing on articles pertinent to SDG 03. Data analysis was performed using the Biblioshiny App through RStudio, examining publication trends, authorship patterns, citation networks, and other bibliometric indicators. The findings reveal a steady increase in research output, moderate citation impact, extensive references, and collaborative authorship, with limited international collaboration. The study underscores the growing interest and research activity in robotic tablet dispensing machines for elderly care while highlighting areas for further global engagement.
    Keywords:  Adherence; Automatic pill dispenser; Healthcare; Medication management; Robotic assistance
    DOI:  https://doi.org/10.1016/j.rcsop.2024.100545
  15. Discov Oncol. 2024 Dec 18. 15(1): 781
    Developmental trends and knowledge frameworks in the application of radiomics in prostate cancer: a bibliometric analysis from 2000 to 2024.
    Pan Hao, Ruiqiang Xin, Yancui Li, Xu Na, Xiaoyong Lv.
       BACKGROUND: This research utilized the bibliometrics method to analyze the published literature related to prostate cancer (PCa) imaging. Furthermore, current knowledge and research hotspots of radiomics in PCa diagnosis and treatment were comprehensively reviewed, as well as progress and emerging trends in field were explored.
    METHODS: In this investigation, the relevant literature on radiomics, and PCa was retrieved from Web of Science Core Collection (WoSCC) databases from 2000 and 2024. Furthermore, a comprehensive bibliometric analysis was carried out using advanced tools like CiteSpace6.2, VOS viewer, and the 'bibliometrix' package of R software to visualize the annual distribution of publications across various aspects such as authors, countries, journals, institutions, and keywords.
    RESULTS: This analysis included 593 from 58 countries including China and the United States. Chinese Academy of Sciences and Frontiers in Oncology were the institutions and journals that publish the most relevant articles, -while Radiology journal had the greatest number of co-cited publications. Furthermore, 3,621 authors published on this topic, of which Madabhushi Anant and Stoyanova Radka had the highest contributions. Moreover, Lambin, P. had the most co-citations. In addition, the diagnostic characteristics of radiomics in PCa imaging and treatment strategies are the current research focal points. The establishment of multi-functional imaging techniques and independent factor models warrants future investigation.
    CONCLUSIONS: In summary, this analysis revealed that the research on PCa imaging is developing vigorously, focusing on the diagnostic methods and intervention measures of imaging in PCa diagnosis and treatment. In the future, there is an urgent need for improved collaboration and communication among countries and institutions.
    Keywords:  Bibliometric; Cite space; Prostate cancer; Radiomics
    DOI:  https://doi.org/10.1007/s12672-024-01678-7
  16. Hum Vaccin Immunother. 2024 Dec 31. 20(1): 2365500
    A bibliometric analysis of vaccination against atherosclerosis.
    Bochao Jia, Rui Wei, Chenlu Yuan, Tao Cheng, Shuai Shi, Yuguang Chu, Yuanhui Hu.
      A growing body of research indicates the promising potential of vaccines in both preventing and treating atherosclerosis (AS). To gain a comprehensive understanding of the current research landscape and emerging trends in this field, this study conducted a bibliometric analysis of publications on AS vaccines using the Web of Science Core Collection (WoSCC) database, based on the "bibliometric" R package and VOSviewer software. From 1991 to 2024, a total of 462 publications were identified in the WoSCC. The United States appeared as the leading contributor in terms of both total publications and citations. The Vaccine journal exhibited the highest publications output. Nilsson J from the Lund University in Sweden was the author with the most published articles, total citations and Hirsch index (H-index). Keywords analysis and thematic maps analysis revealed the passive immunotherapy (AS protective antibodies vaccines) was a hot mature theme, the active immunotherapy (AS antigens vaccines) was an emerging and booming theme, while the efficacy and safety of AS vaccines was a niche and well-developed theme. These findings offered valuable insights into the AS vaccination and provided guidance for future research in this domain.
    Keywords:  Vaccines; adjuvant; antibody; antigen; atherosclerosis; bibliometrics; research hotspots; research trends
    DOI:  https://doi.org/10.1080/21645515.2024.2365500
  17. Quant Imaging Med Surg. 2024 Dec 05. 14(12): 8899-8914
    Analysis of tumor treatment under interventional ultrasound through structural and temporal dynamics: a bibliometric visualization.
    Siyu Liang, Kangchun Wang, Feiyang Liu, Ben Li, Haiping Du, Xin Yu, Baomei Yan, Bei Zhao.
       Background: Ultrasound is considered one of the most crucial tools for image-guided tumor ablation, and provides a vital alternative approach to tumor treatment. This study used bibliometric methods to characterize the development history of tumor treatment under interventional ultrasound and explore future research hotspots.
    Methods: In this study, we retrieved and selected publications on tumor treatment under interventional ultrasound from the Web of Science Core Collection (WoSCC) database published from 1960 to 2023. In total, 2,588 articles were included in our study. A bibliometric analysis was conducted to explore various aspects of this field, such as global publication trends, institutional and author collaborations, high-impact journals, highly cited publications, and the evolution of research hotspots.
    Results: Our results revealed that the global publication output in this field has continuously increased over the past few decades with China and the United States emerging as the most active contributors and maintaining close collaborative relationships. Several institutions and authors, including Chongqing Medical University, had a high publication volume, high citation counts, and a high number of collaborations in this field. Journals like the "Journal of Urology" and "Ultrasound in Medicine and Biology" have enriched the literature resources and fostered developments in this field. In addition, a keyword analysis revealed the main focus areas in this field.
    Conclusions: Based on our analysis, we found that the focus of research on tumor treatment under interventional ultrasound has shifted from the exploration of clinical applications to technological advancements and safety. This study also revealed the historical trajectory and identified future trends in this field.
    Keywords:  Interventional ultrasound; ablation; bibliometrics; high-intensity focused ultrasound (HIFU); tumor treatment
    DOI:  https://doi.org/10.21037/qims-24-1233
  18. Healthcare (Basel). 2024 Dec 06. pii: 2467. [Epub ahead of print]12(23):
    Human-Computer Interaction in Healthcare: A Bibliometric Analysis with CiteSpace.
    Xiangying Zhao, Shunan Zhang, Dongyan Nan, Jiali Han, Jang Hyun Kim.
       BACKGROUND/OBJECTIVES: Studies on the application and exploration of human-computer interaction (HCI) technologies within the healthcare sector have rapidly expanded, showcasing the immense potential of HCI to enhance medical services, elevate patient experiences, and advance health management. Despite this proliferating interest, there is a notable shortage of comprehensive bibliometric analyses dedicated to the application of HCI in healthcare, which limits a thorough comprehension of the growth trends and future trajectories in this area.
    METHODS: To bridge this gap, we employed bibliometric methods using the CiteSpace tool to systematically review and analyze the current state and trends of HCI research in healthcare. A meticulous topic search of Web of Science yielded 3598 papers published between 2004 and 2023.
    RESULTS: Through literature analysis, the most productive researchers, institutes, and countries/territories and the collaboration networks among authors and countries within the field were analyzed. Additionally, by conducting a co-citation analysis, journals and literature with high citation rates and influence within the academic community in this field were revealed. Through a cluster analysis based on literature co-citations and keyword burst analyses, we further explored the main research themes and hot topics within the fields of healthcare and HCI.
    CONCLUSIONS: In summary, through a comprehensive and systematic bibliometric analysis, this study provides a solid knowledge foundation for HCI in the healthcare research community, thereby fostering the development of innovative research and the optimization of practical applications in the field.
    Keywords:  CiteSpace; HCI; bibliometric analysis; healthcare
    DOI:  https://doi.org/10.3390/healthcare12232467
  19. Digit Health. 2024 Jan-Dec;10:10 20552076241305233
    Visual analysis of research trends and hotspots in wearable electronic devices in the medical field: A bibliometric study.
    Ni Zhang, Yanyang Peng, Qing Guo.
       Background: Healthcare services and functionalities need comprehensive upgrades, and advancements in information technology have driven research in wearable electronic devices (WDs), making them critical tools for this purpose.
    Objective: To conduct a systematic bibliometric analysis of WDs in the medical field and understand research trends.
    Methods: A literature search of articles related to WDs in the medical field was conducted in the Web of Science Core Collection (WoSCC) from 2013 to 2023. Articles were analyzed using CiteSpace 6.1.R6.
    Results: Publications on WDs have increased yearly since 2014, peaking in 2021. The United States leads with 935 articles. PLOS One is the top journal, and Bland et al. have the highest citation frequencies. Hot topics include mobile apps, phones, and neural networks, with research on physical activity, sleep monitoring, and atrial fibrillation.
    Conclusions: This study identifies key journals, countries, institutions, and authors in WDs research, highlighting trends and global interest in health monitoring and assessment. The United States leads in research, with future trends focusing on neural network monitoring, accuracy improvements, cloud storage, and advancements in healthcare management systems.
    Keywords:  Wearable electronic devices; development trends; health management; medical care; research hotspots
    DOI:  https://doi.org/10.1177/20552076241305233
  20. J Asthma Allergy. 2024 ;17 1271-1285
    Research Trends and Hotspots on Asthma and Depression: A Bibliometric Analysis.
    Guoran Peng, Beibei Cheng, Rongzhen Ding, Aiguo Dai.
       Purpose: Asthma and depression are prevalent conditions with significant comorbidity, impacting patients' quality of life. This bibliometric study aims to analyze research trends and hotspots in the field from 2000 to 2023, identifying key contributions and predicting future directions.
    Methods: We conducted a systematic search in the Web of Science Core Collection (WoSCC) for articles on asthma and depression, published between 2000 and 2023. Bibliometrics, which involves the application of mathematical and statistical methods to analyze scholarly literature, was employed in this study to systematically assess the research trends and hotspots in the field of asthma and depression. VOSviewer and CiteSpace software were utilized for visual analysis and data visualization, enabling us to map collaboration networks and identify research hotspots and trends within the asthma and depression literature.
    Results: Our analysis retrieved 3067 papers from 937 journals, involving 14,631 authors and 4006 institutions across 106 countries. The United States, Columbia University, the Journal of Asthma, and Christer Janson were the most prolific contributors. Six primary research themes emerged: quality of life, childhood asthma, primary care, substance P, intervention, and emotion. Additionally, Burst detection analysis identified emerging topics, including severe asthma, other respiratory diseases, and oxidative stress.
    Conclusion: This bibliometric analysis has revealed significant insights into the research trends and hotspots in the field of asthma and depression. The primary findings indicate a growing body of research highlighting the impact of depression on asthma control and patients' quality of life, the need for psychological interventions in treating comorbid asthma and depression, and the emerging focus on severe asthma and oxidative stress mechanisms. These findings underscore the importance of continued research in these areas to advance our understanding and improve clinical outcomes for patients with these comorbid conditions.
    Keywords:  asthma; bibliometric analysis; depression; hotspots; research trends
    DOI:  https://doi.org/10.2147/JAA.S495814
  21. World J Psychiatry. 2024 Dec 19. 14(12): 1971-1981
    Bibliometric and visual study of narcolepsy from 2000 to 2023.
    Chao Yang, Li-Li Sun, Shuai Wang, Huan Li, Kai Zhang.
       BACKGROUND: More studies explored the prevalence, causes, associated conditions, and therapeutic strategies of narcolepsy. With an increasing focus on understanding narcolepsy's prevalence, associated conditions, and therapeutic strategies, there's a notable absence of bibliometric analyses summarizing trends in research and identifying emerging areas of focus within this field.
    AIM: To conduct a bibliometric analysis to investigate the current status and frontiers of narcolepsy.
    METHODS: The documents related to narcolepsy are obtained from the Web of Science Core Collection database (WoSCC) from January 1, 2000, to December 31, 2023, and VOS viewer 1.6.16, and the WoSCC's literature analysis wire were used to conduct the bibliometric analysis.
    RESULTS: A total of 4672 publications related to narcolepsy were included, and 16182 authors across 4397 institutions and 96 countries/regions contributed to these documents in 1131 different journals. The most productive author, institution, country and journal were Yves Dauvilliers, Stanford University, United States, and Sleep Medicine, respectively. The first high-cited document was published in Nature in 2005 by Saper et al, and this research underscores the role of certain neurons in ensuring the stability of sleep-wake transitions, offering insights into narcolepsy's pathophysiology.
    CONCLUSION: In conclusion, the main research hotspots and frontiers in the field of narcolepsy are the diagnosis of narcolepsy, pathological mechanism of narcolepsy and the treatment of narcolepsy. More studies are needed to explore effective strategies for the diagnosis and treatment of narcolepsy.
    Keywords:  Bibliometric analysis; Diagnosis; Mechanisms; Narcolepsy; Treatment
    DOI:  https://doi.org/10.5498/wjp.v14.i12.1971
  22. Hum Vaccin Immunother. 2024 Dec 31. 20(1): 2435644
    Global research trends in the relationship between influenza and CD4+ T/CD8+ T cells: A bibliometric analysis.
    Yanping Zong, Hui Li, Yonglong Chang, Jiajie Li, Lei He, Weibing Shi, Jinchen Guo.
      Influenza pathogens cause many illnesses and deaths yearly, posing a serious threat to global public health. As a result, most studies are increasingly focusing on the role of specific CD4+ T/CD8+ T cells in combating influenza. This study examines the key themes and trends in this field using bibliometric analysis. Literature on influenza and CD4+ T/CD8+ T cells were searched (from 1985 to 2023) in the Web of Science Core Collection (WoSCC) database. Eligible articles were screened according to the inclusion and exclusion criteria for bibliometric analysis using VOSviewer, CiteSpace, and the R package "bibliometrix." A total of 1,071 publications from 47 countries or regions and 1,148 institutions associated with 5,728 authors in the disciplines of immunology, virology, biochemistry, and molecular biology were included. The findings indicate a yearly increase in publications related to influenza and CD4+ T/CD8+ T cells, with the United States, Australia, and China leading in publication volume. The University of Melbourne had the highest volume of publications. Only a few researchers collaborated, and the collaborations were mostly concentrated in the same countries/regions. Professor Katherine Kedzierska, associated with The Peter Doherty Institute for Infection and Immunity, was the most productive academic in this field. According to the analysis of highly cited literature and keywords, the application of cellular immunity in formulating pioneering influenza vaccines is a key direction for future research.The role of CD4+ T/CD8+ T cells in combating the influenza virus has emerged as a significant focus within influenza research literature. This article summarizes the research institutions, authors, journals, hotspots, and application trends of CD4+ T/CD8+ T cells in influenza.
    Keywords:  Bibliometric analysis; CD4+ T/CD8+ T cells; Citespace; Influenza; VOSviewer; research trends
    DOI:  https://doi.org/10.1080/21645515.2024.2435644
  23. Hum Vaccin Immunother. 2024 Dec 31. 20(1): 2363019
    Bibliometric and visual analyses of vaccine literacy research from 1982 to 2023.
    Jingzhi Wang, Yazhou Wang, Yuanheng Li, Mingxue Ma, Yuzhuo Xie, Yuwei Zhang, Jiaqi Guo, Jiajun Shi, Chao Sun, Haoyu Chi, Hanye Tang, Vsevolod Ermakov, Mingli Jiao.
      Vaccine literacy (VL) is an important part of health literacy (HL), which is of great significance in reducing vaccine hesitancy and improving vaccine coverage rate. We aimed to perform a bibliometric analysis of VL research conducted from 1982 to 2023 to evaluate its current status and prospects. All relevant publications were retrieved from the Web of Science Core Collection database and the Scopus database. The Bibliometrix R-package and VOSviewer software were used to analyze the publication outputs, countries, organizations, authors, journals, cited publications, and keywords. In total, 1,612 publications were included. The number of articles published on VL generally showed an increasing trend. The United States was in a leading position among all countries and had the closest connections with other countries and organizations. Its in-depth study of vaccine hesitancy provided a good foundation for VL research. Harvard University was the most productive organization. Bonaccorsi G was the most productive and cited author. VACCINES was the most productive journal. Research topics primarily revolved around vaccination, HL, vaccine hesitancy, and COVID-19 vaccine. In conclusion, the current research on the conceptual connotation and influencing factors of VL is insufficiently deep and should be further improved in the future to distinguish it from HL in a deeper manner. More tools for measuring VL need to be developed, such as those applicable to different populations and vaccines. The more complex relationship between VL, vaccine hesitancy and vaccination needs to be further explored. Gender differences deserve further investigation.
    Keywords:  Bibliometrix; VOSviewer; Vaccine literacy; bibliometric analysis; visualization
    DOI:  https://doi.org/10.1080/21645515.2024.2363019
  24. Heliyon. 2024 Dec 15. 10(23): e39370
    Global research trends in the teacher evaluation of medical college: A bibliometric and visualized study.
    Yan Song, Yanpeng Jin, Sifan Wang, Jianan Liu, Yanhan Duan, Haoyang Chen, Haijiang Wu.
       Background: The evaluation of education in colleges and universities is not only an essential means to promote teachers' professional development and ensure high-quality development of education but also a strong support for the overall development of colleges and universities. In this study, to understand the development trends and predict the future of teacher evaluation in medical colleges from 2005 to 2023, we conducted a comprehensive bibliometric and visualized study using Web of Science.
    Methods: The articles on teacher evaluation in medical colleges were extracted from the "Core Collection" of the WoS database. VOSviewer software, CiteSpace and R-Bibliometrix Package were employed to visually analyze countries/regions, journals, authors, keywords, institutions, and highly cited articles in this field.
    Results: The number of articles on teacher evaluation in medical colleges has gradually increased. The United States has the most significant number of publications in this field. The most frequently used keywords were "medical education," "education," "teaching," "assessment," and "curriculum." BMC Medical Education was the leading journal. The leading institutions were Pontificia Universidad Católica de Chile and the University of Toronto. Furthermore, Singh T, Roberts C, Riquelme A, Raupach T, and Padilla O published the most papers.
    Conclusion: This study's results indicate that teacher evaluation in medical colleges remains a significant area of research worldwide. The findings will contribute to the ongoing study of teacher evaluation in medical colleges.
    Keywords:  Bibliometric analysis; Medical college; Teacher evaluation
    DOI:  https://doi.org/10.1016/j.heliyon.2024.e39370
  25. J Multidiscip Healthc. 2024 ;17 5901-5915
    Bibliometric Analysis of Comprehensive Geriatric Assessment from 2004 to 2023.
    Fan Zhang, Yujun Xiong, Xiangda Meng, Huazhao Xu, Qiuli Zhang.
       Background: The global aging population necessitates specialized tools for complex geriatric health issues. Comprehensive Geriatric Assessment (CGA) provides multidimensional evaluations of elderly, integrating inputs from various professionals to create individualized care plans. This study aims to visually assess the research trends and hotspots in the field of CGA, review mainstream perspectives in this field, and provide a foundation for future research and treatment.
    Methods: Original and review articles related to comprehensive geriatric assessment, published from 2004 to December 2023, were extracted from the Web of Science database. Four different software tools-CiteSpace, VOSviewer, Bibliometrix R package, and the Online Analysis Platform of Bibliometrics-were utilized for this comprehensive analysis.
    Results: According to our retrieval strategy, we found a total of 4,411 related literatures. There has been a substantial increase in the research on comprehensive geriatric assessment in the past 20 years. These publications have been cited 157,366 times, with a mean of 35.68 citations per publication. The largest number of publications were from the US, and Italy ranked second (14.98%). Keyword burst and concurrence showed that "randomized trial", "adjuvant chemotherapy" and "breast cancer" were the top 3 most frequently occurring keywords.
    Conclusion: Our bibliometric analysis reveals significant growth in CGA research over the past two decades, with a shift from cancer-focused studies to chronic conditions like frailty and sarcopenia. These findings highlight evolving priorities in geriatric care and underscore the need for future research to integrate technological advancements, such as AI, to enhance the precision, scalability, and cost-effectiveness of CGA in diverse settings.
    Keywords:  CiteSpace; VOSviewer; bibliometric analysis; comprehensive geriatric assessment; frailty
    DOI:  https://doi.org/10.2147/JMDH.S488030
  26. Asian J Anesthesiol. 2024 Dec 20. 62(1): 46-62
    Top 100 Most-Cited Articles on Difficult Airway Management From 2011 to 2022: A Bibliometric Analysis.
    Lawrence Huang, Steven H Hsu, Yi Ting Chuang, Yu Hsuan Tang, Hsien Yung Lai.
       BACKGROUND: Difficult airway management (DAM) presents a complex array of challenges inherent in establishing and maintaining a patient's airway during medical procedures or emergencies. Consequences of compromised DAM are profound, ranging from hypoxia, and aspiration, to cardiac arrest. Despite the ongoing progress and innovation in airway management, DAM remains a significant clinical challenge. Performing a bibliometric analysis of the most cited articles in this domain offers quantitative and qualitative insights into the landscape and trend of key research; our analysis revealed an increasing focus on video laryngoscopy research over the past decade, with a notable surge in studies related to airway management during infectious disease outbreaks in recent years.
    METHODS: We performed a bibliometric analysis of the 100 most-cited articles on DAM (Top100DAM) published between 2011 and 2022, sourced from both PubMed and Web of Science databases. Employing social network analysis, we identified key associated topics and cluster terms. Cluster terms are broad categories encompassing related topic terms. Topic terms are specific keywords or phrases found in the articles. Citation counts were estimated for each article, and cluster-specific reviews were generated using the Medical Query Expert software.
    RESULTS: The Top100DAM comprised 53 topic terms spanning 11 cluster terms. "Anesthesiology" stood out as the most frequently featured cluster, and "betacoronavirus" had the highest Impact Factor. There was a significant correlation between the counts between the inferred citation based on cluster terms and the observed citation (Pearson's R = 0.06, P = 0.02). To visualize, the network visualization and Sankey diagrams were used to illustrate the characteristics of the articles. The generated summary, utilizing natural language processing techniques, underscored the role of fiber-optic technology and video laryngoscopy in addressing DAM. During the COVID-19 pandemic, experts recommended the provision of supplemental oxygen and the prioritization of video laryngoscopy for anticipated DAM scenarios. Notably, the most cited articles predominantly concentrated on the importance of practice driven by guidelines and protocols for clinicians and anesthesiologists to manage difficult airways effectively.
    CONCLUSION: DAM plays a central role in anesthesiology research, with a significant emphasis on guideline development, technological advancements like video laryngoscopy, and adapting practices for infectious disease scenarios. The increased publication volume and high citation rates during the COVID-19 pandemic underscore how ongoing research and innovation have accelerated, refining DAM practices. Articles with high citation rates mostly pertain to guidelines, illustrating their substantial impact on clinical practice and the necessity for studies to base their discussions on these guidelines. Future research should focus on addressing the implementation challenges of existing guidelines and developing context-specific protocols for diverse clinical settings.
    DOI:  https://doi.org/10.6859/aja.202403_62(1).0006
  27. Cancer Control. 2024 Jan-Dec;31:31 10732748241310937
    Research Hotspots and Trends of NK Cell Immunotherapy for Acute Myeloid Leukemia: A Bibliometric Analysis From 2000 to 2023.
    Shupeng Chen, Jie Liu, Kaiyue Xia, Yao Gao, Yingjian Zeng.
       BACKGROUND: Natural killer (NK) cell immunotherapy has shown promising therapeutic potential for acute myeloid leukemia (AML), especially with advancements in chimeric antigen receptor-engineered NK cells (CAR-NK) and artificial intelligence (AI). Despite these developments, the field lacks comprehensive bibliometric analyses to identify research hotspots and trends, which could guide future precision treatments.
    METHODS: A bibliometric analysis of NK cell immunotherapy for AML was conducted using literature from 2000 to 2023 retrieved from the Web of Science Core Collection database. Data visualization tools like CiteSpace, VOSviewer, and RStudio were employed to analyze publication trends, country contributions, institutional collaborations, influential authors, and research themes.
    RESULTS: The analysis identified 1513 studies, with the United States and China leading global contributions. Notable institutions include the University of Minnesota and MD Anderson Cancer Center. Hot topics include allogeneic NK therapy, CAR-NK cell therapy, and memory-like NK cells. Emerging trends highlight the integration of intelligent NK cells and combinatory therapies, offering promising avenues for AML treatment. Despite progress, challenges such as NK cell expansion, activation, and resistance mechanisms remain critical areas for research.
    CONCLUSION: This study provides a comprehensive overview of the research landscape, highlighting the transformative potential of NK cell immunotherapy in AML. It underscores the need for international collaboration and continued innovation to overcome existing challenges and advance precision therapies.
    Keywords:  AML; CAR-NK cell therapy; NK cells; allogeneic NK cell therapy; bibliometrics; intelligentization; memory-like NK cell therapy
    DOI:  https://doi.org/10.1177/10732748241310937
  28. Gland Surg. 2024 Nov 30. 13(11): 2078-2097
    Bibliometric analysis and visualization of global research trends in primary thyroid lymphoma via CiteSpace.
    Hao Gong, Yuhan Jiang, Tianyuchen Jiang, Yi Yang, Zhujuan Wu, Jie Xiao, Anping Su.
       Background: Primary thyroid lymphoma (PTL) is a rare malignancy of the thyroid gland that poses significant clinical challenges due to its rarity and the varied therapeutic approaches it demands. Although recent years have seen an increasing focus on PTL, there is a notable lack of bibliometric analyses that consolidate the evolving research within this field. This study aims to analyze and highlight the research hotspots and trend changes in PTL, elucidating their clinical implications and guiding future research.
    Methods: We conducted a systematic bibliometric analysis of literature on PTL published from 2000 to 2023. This involved a structured search in the Web of Science Core Collection, using medical subject headings (MeSH) from the MeSH database to refine and eliminate duplicates, forming a precise search formula. Relevant publications were limited to English-language articles and reviews, which were then processed and analyzed using CiteSpace (6.2.R4) for visualization. The analysis, performed with CiteSpace software, facilitated the visualization of trends and hotspots in PTL research by mapping citation networks and identifying key themes and influential works.
    Results: Our search yielded 281 literature records on PTL, demonstrating a curvilinear upward trend in publications over the years. The majority of publications originated from China, with the most influential contributions coming from the United States. Hirokawa Mitsuyoshi and Derringer Ga were identified as the most prolific and most co-cited authors, respectively. Keyword and co-citation analyses indicated a growing interest in clinicopathological features, treatment modalities, survival outcomes of different PTL subtypes, risk factors, complementary diagnostic techniques, and immunotherapeutic approaches.
    Conclusions: This bibliometric analysis underscores the significant clinical relevance of understanding the pathologies, diagnostic challenges, and treatment strategies for PTL. The identified research hotspots, particularly in pathological typing, diagnosis and treatment modalities, gene expression profiles, targeted therapies, clinical trials, and survival rates, highlight critical areas requiring continued research focus. These insights have pivotal implications for improving patient outcomes and advancing the clinical management of PTL.
    Keywords:  CiteSpace; Primary thyroid lymphoma (PTL); bibliometric; therapy; trend analysis
    DOI:  https://doi.org/10.21037/gs-24-317
  29. Front Immunol. 2024 ;15 1460533
    Antiangiogenic therapy exerts antitumor effects by altering the tumor microenvironment: bibliometric analysis.
    Yuan Kang, Yixin Kang, Dianbao Zhang, Jun Yao.
       Background: Antiangiogenic therapy can alter the tumor microenvironment (TME) and thus exert anti-tumor effects, and has the potential to increase the efficacy of conventional therapy and immunotherapy. The aim of this study was to examine current research hotspots and collaborative networks on the relationship between previous antiangiogenic therapies and the TME through bibliometric analysis.
    Method: From the Web of Science Core Collection database, all publications from inception through December 2023 were downloaded. In-depth analysis was performed by Bibliometrix packages in R. Keywords and collaborative networks were analyzed using VOSviewers and Citespace.
    Result: We obtained a total of 9027 publications. They come from 27 countries and were published in 1387 journals, with a total of 39,604 authors in the studied area. The number of publications increases dramatically from 2014 to 2023, accounting for 73.87% (6668/9027) of all publications. China and CANCERS have the highest number of publications on this topic and CANCER RESEACH is the most influential. In the last decade (2013- 2023), research has gradually shifted from studying the role of vascular endothelial growth factor in the TME to examining how antivascular therapy can contribute to the progression of cancer treatment. Furthermore, nanoparticle-based drug delivery systems and immunotherapy have been widely explored in the past five years. The findings of this study will help scientists to explore this promising field in depth by providing insight into the relationship between antiangiogenic therapy and the TME.
    Conclusion: The relationship between the antiangiogenic therapy and the TME has been developing rapidly, but cooperation between different institutions and countries is still limited. Researchers can use this study to identify hotspots and develop trends for related research, thereby facilitating the development and cooperative exchange in this field, as well as to suggest potential future research directions.
    Keywords:  angiogenesis; antiangiogenic; bibliometric; the tumor microenvironment; therapy
    DOI:  https://doi.org/10.3389/fimmu.2024.1460533
  30. J Cardiothorac Surg. 2024 Dec 20. 19(1): 659
    Research on rheumatic heart disease from 2013 to early 2024: a bibliometric analysis.
    Yifan Chen, Liuding Wang, Dan Ma, Zhijie Cui, Yanjiao Liu, Qinghua Pang, Zhonghui Jiang, Zhuye Gao.
       OBJECTIVES: The aim of this bibliometric analysis was to highlight potential future areas for the practical application of research on rheumatic heart disease (RHD), considering past and current research efforts.
    METHODS: A systematic search was conducted in the WoSCC to find articles and reviews focused on RHD published between 2013 and 2024. Microsoft Excel 2019 was used to chart the annual productivity of research relevant to RHD, while ArcGIS (version 10.8) was employed to visualize the global distribution of publications. Analysis tools such as CiteSpace (version 6.1.R6) and VOSviewer (version 1.6.18) were utilized to identify the most prolific countries or regions, authors, journals, and resource-, intellectual-, and knowledge-sharing in RHD research, and to perform co-citation analysis of references and keywords. Additionally, the Bibliometrix R Package was used to analyze topic dynamics.
    RESULTS: From the search, a total of 2,428 publications were retrieved. In terms of countries or regions, the United States was the most productive country (566, 23.31%). As for institutions, most publications have been contributed by the University of Cape Town (149, 6.14%). Regarding authors, Jonathan R. Carapetis produced the most published works, and he received the most co-citations. The most prolific journal was identified as the International Journal of Cardiology (70, 2.88%). The study published in Circulation received the most co-citations. Keywords with ongoing strong citation bursts included "surgical treatment" and "valvular heart disease".
    CONCLUSION: Despite the rapid advancements in the field of RHD research, future efforts should prioritize strengthening collaboration among national institutions to facilitate information dissemination. Current research on RHD mainly focuses on prognosis of patients. While, the emerging research trends in RHD encompass treatment strategies for complications, including atrial fibrillation (AF), heart failure (HF), and infective endocarditis, as well as screening strategies for RHD and surgical interventions for patients with rheumatic mitral valve disease.
    Keywords:  Atrial fibrillation; Bibliometric study; Heart failure; Rheumatic heart disease; Surgical options
    DOI:  https://doi.org/10.1186/s13019-024-03175-y
  31. Medicine (Baltimore). 2024 Dec 13. 103(50): e40931
    Hotspots and development trends of gut microbiota in atopic dermatitis: A bibliometric analysis from 1988 to 2024.
    Fang Liu, Haipeng Zhang, Lina Fan, Qi Yu, Siqiao Wang.
       BACKGROUND: Atopic dermatitis (AD) is a prevalent inflammatory skin condition that commonly occurs in children. More and more scientific evidence suggests that gut microbiota plays an important role in the pathogenesis of AD, whereas there is no article providing a comprehensive summary and analysis. We aimed to analyze documents on AD and gut microbiota and identify hotspots and development trends in this field.
    METHODS: Articles and reviews in the field of AD and gut microbiota from January 1, 1988 to October 20, 2024 were obtained from the Web of Science Core Collection database. Biblioshiny was utilized for evaluating and visualizing the core authors, journals, countries, documents, trend topics, and hotspots in this field.
    RESULTS: Among 1672 documents, it indicated that the number of annual publications generally increased. The United States had the highest production, impact, and international collaboration. Journal of Allergy and Clinical Immunology was the journal of the maximum publications. Based on keyword co-occurrence and clustering analysis, "stratum-corneum lipids," "probiotics," "prebiotics," "fecal microbiota transplantation," "phage therapy," "short chain fatty-acids," "biologic therapy," and "skin inflammation" represented current trend topics. The pathological and molecular mechanisms and associated therapeutic methods for AD and gut microbiota were the research hotspots. The incorporation of microbiota-based therapies alongside conventional treatments can contribute to better clinical outcomes.
    CONCLUSION: We highlighted that gut microbiota may exacerbate symptoms of AD through various aspects, including immunity, metabolites, and neuroendocrine pathways. More efforts are required to investigate the safety and efficacy of gut microbial management methods for the prevention and treatment of AD.
    DOI:  https://doi.org/10.1097/MD.0000000000040931
  32. J Clin Neurosci. 2024 Dec 17. pii: S0967-5868(24)00531-9. [Epub ahead of print]132 110992
    Low Middle Income Countries and Academic Productivity of Neurosurgery: A Quantitative Analysis From Pakistan.
    Kaleem Ullah Ranjha, Syeda Fatima Abid, Muhammad Hammad Khan, Muhammad Shayan Waheed, Laiba Sarfraz, Muhammad Kashif, Ahmed Muthana, Samer S Hoz, Minaam Farooq.
      Neurosurgical training and practice rely heavily on research, which is a pivotal marker of academic productivity. This study investigates the current landscape of neurosurgery publications originating from Pakistan, encompassing overall research output, prevalent topics, and disparities across institutions and regions. Electronic databases, including PubMed, Scopus, Web of Science, and ScienceDirect, were systematically searched up to November 1, 2023, using specified keywords. Data pertaining to authors, publication years, affiliations, article types, citations, journals, impact factors, and topics were extracted from eligible articles. From inception till Nov 1, 2023, a total of 825 articles relating to Neurosurgery were published from Pakistan. A significant upsurge in publications occurred from 2017 onwards, reaching its peak in 2021 with 115 studies published. A total of 12 articles had 100 or more citations. The majority of publications were original articles (n = 592, 71.7 %) followed by reviews (n = 144, 17.5 %), predominantly focusing on brain-related topics (n = 203, 24.6 %), neuro-oncology (n = 164, 19.8 %), spine (n = 145, 17.5 %), and trauma (n = 143. 17.3 %). Vascular neurosurgery contributed 88 studies, general neurosurgery 40, neuroradiology 28, functional neurosurgery 14, and pediatric neurosurgery 17. Shamim MS was the top author with the most number of publications (n = 89), followed by Enam SA (n = 51). JPMA (n = 93) and Surgical Neurology International (n = 71) emerged as the top publishing journals. Aga Khan University and Hospital emerged as the most prolific contributor with 236 original studies conducted. There exists notable regional disparities and a lack of experimental studies. While there has been a substantial increase in neurosurgical publications from Pakistan in recent years, significant regional disparities and challenges persist. Addressing these issues is crucial to fostering a more robust research environment in neurosurgery within the country.
    Keywords:  Neurosurgeons; Neurosurgery; Pakistan; Publications; Research; Scientific productivity
    DOI:  https://doi.org/10.1016/j.jocn.2024.110992
  33. Hum Vaccin Immunother. 2025 Dec;21(1): 2443281
    Research trends and key contributors in studies on influenza vaccines for children: A 20-year bibliometric analysis.
    Ning Sun, Rui Wei, Bochao Jia, Taiwei Lou, Zirong Li, Xiaowei Nie, Wenxiao Yu, Miaoran Wang, Qiuyan Li.
      Globally, there are over 3 million severe cases of influenza each year, leading to up to half a million deaths. This study provides a comprehensive analysis of the current status of children's influenza vaccine research over the past 20 years and explores potential future research trends, including improvements in vaccine coverage and strategies to address vaccine hesitancy. We extracted all research data on children's influenza vaccines from 2004 to 2024 using the Web of Science Core Collection (WOSCC). The contributions of various countries/regions, institutions, authors, and journals in this field were assessed, and research hotspots as well as promising future trends were predicted through keyword analysis using CiteSpace and VOSviewer. A total of 2,598 related publications from 2004 to 2024 were identified and collected for analysis. The United States (USA) and England emerged as the leading contributors with the highest number of published papers. AstraZeneca was identified as a key leader among research institutions, and Ambrose Christopher S was recognized as the most productive author in this field. The journals Vaccine and Human Vaccines & Immunotherapeutics stood out as the most prominent publications in this area. The keyword analysis highlighted that international research collaboration maybe a promising strategy for bridging global gaps; Addressing vaccine hesitancy could potentially increase vaccination coverage; Live attenuated vaccines, intranasal administration and universal vaccines are promising directions for future development. These insights highlight potential avenues for improving influenza vaccine coverage and inform strategies to mitigate vaccine hesitancy, crucial for protecting children and enhancing public health.
    Keywords:  CiteSpace; Influenza vaccine; bibliometrics; children; visual analysis
    DOI:  https://doi.org/10.1080/21645515.2024.2443281
  34. Medicine (Baltimore). 2024 Dec 13. 103(50): e40715
    Bibliometric analysis of research developments in oral and maxillofacial neuralgia from 2004 to 2023.
    Yuhang Cai, Keyi Liu, Junwei Xiang, Hu Zheng, Dezhi Zhang, Yuanyin Wang, Ran Chen.
      This study employs bibliometric techniques to dynamically represent the research landscape of oral and maxillofacial neuralgia. Its goal is to pinpoint research hotspots and delineate forthcoming trends. A systematic search of the Web of Science Core Collection was performed using targeted keywords to retrieve literature from January 2004 to December 2023. Citespace version 6.2.6 was utilized to analyze countries, institutions, authors, co-cited journals, and keywords. The analysis indicates an annual increase in research literature on oral and maxillofacial neuralgia, albeit with a decline observed in the past 2 years. In the last 5 years, a total of 279 publications have been produced, predominantly by developed countries. The average betweenness centrality exceeds 0.1. Analysis of co-cited literature revealed 100 nodes, with research frontiers closely associated with trigeminal neuralgia, gamma knife radiosurgery, percutaneous balloon compression, among others. Keyword clustering analysis generated 61 nodes, primarily concentrated on 3 research areas: gamma knife, microvascular decompression, and hemifacial spasm. The emergence of keywords closely correlates with trigeminal neuralgia. Research frontiers in the field of oral and maxillofacial neuralgia are primarily focused on trigeminal neuralgia, with major therapeutic approaches including gamma knife radiosurgery and percutaneous balloon compression. These areas, along with botulinum toxin, represent current hotpots and are likely to drive the future direction of research in treating oral and maxillofacial neuralgia.
    DOI:  https://doi.org/10.1097/MD.0000000000040715
  35. PeerJ. 2024 ;12 e18645
    N6-methyladenosine (m6A) modification in inflammation: a bibliometric analysis and literature review.
    Zewen Li, Yongfeng Lao, Rui Yan, Xin Guan, Yanan Bai, Fuhan Li, Zhilong Dong.
      N6-methyladenosine (m6A) is the most abundant internal messenger RNA modification in eukaryotes, influencing various physiological and pathological processes by regulating RNA metabolism. Numerous studies have investigated the role of m6A in inflammatory responses and inflammatory diseases. In this study, VOSviewer and Citespace were used to perform bibliometric analysis to systematically evaluating the current landscape of research on the association between m6A and inflammation. The literature was sourced from the Web of Science Core Collection, with characteristics including year, country/region, institution, author, journal, citation, and keywords. According to the bibliometric analysis results of keywords, we present a narrative summary of the potential mechanisms by which m6A regulates inflammation. The results showed that the key mechanisms by which m6A modulates inflammation include apoptosis, autophagy, oxidative stress, immune cell dysfunction, and dysregulation of signaling pathways.
    Keywords:  Bibliometrics; Inflammation; Mechanism; Treatment; m6A
    DOI:  https://doi.org/10.7717/peerj.18645
  36. Front Behav Neurosci. 2024 ;18 1501377
    A bibliometric analysis of studies on environmental enrichment spanning 1967-2024: patterns and trends over the years.
    Gaurav Singhal, Bernhard T Baune.
      Environmental Enrichment (EE) has received considerable attention for its potential to enhance cognitive and neurobiological outcomes in animal models. This bibliometric analysis offers a comprehensive evaluation of the EE research spanning from 1967 to 2024, utilizing data extracted from Scopus and analyzed through R and VOSviewer. The volume of publications, citation patterns, and collaborations were systematically reviewed, highlighting important contributions and emerging trends within the field of animal research. Core concepts of EE research are mapped, revealing key themes such as neuroplasticity, cognitive function, and behavioral outcomes. A significant increase in EE research is demonstrated, particularly after the year 2000, reflecting growing scientific and public interest in EE paradigms. This analysis provides insights into the global contributions and collaborative networks that have shaped EE studies over time. The role of EE in advancing the understanding of neurobiological, neurodevelopmental, and neurodegenerative processes is underscored. Influential contributors, leading countries, and high-impact journals in the field of EE are identified, offering a valuable resource for researchers seeking to understand or extend the current knowledge base. The strategic selection of keywords and rigorous data curation methods ensure that the findings accurately reflect the most impactful aspects of EE research in animals. This study serves as an essential reference for future explorations and applications of EE across disciplines. By providing a clear and structured overview of the field, this paper aims to serve as a foundation for ongoing and future research initiatives, encouraging more robust investigations and applications of EE to enhance cognitive and neurological health globally.
    Keywords:  behavior; brain; cognition; environmental enrichment; hippocampus; learning; memory; rodents
    DOI:  https://doi.org/10.3389/fnbeh.2024.1501377
  37. Discov Oncol. 2024 Dec 19. 15(1): 811
    Cancer phenomics research hotspots and development trends: a bibliometric analysis from 2000 to 2023.
    Shupeng Chen, Jie Liu, Nana Tang, Yingjian Zeng.
      The emerging field of cancer phenomics provides comprehensive insights into tumor heterogeneity, promoting advances in personalized oncology. This study explores current research hotspots and future development trends in cancer phenomics through a bibliometric analysis of research from 2000 to 2023. Using data from the Web of Science Core Collection, we analyzed 1260 publications to identify global contributions and collaborative networks. Employing CiteSpace and VOSviewer tools, we examined research trends, highlighting disease progression, multi-omics integration, and phenotypic drug discovery as major focus areas. Key findings reveal that the United States, China, and the United Kingdom are leading contributors, with top institutions such as Harvard Medical School advancing research and fostering international collaboration. Additionally, the analysis underscores the prominence of double-positive (DP) T cells and natural killer (NK) cells in cancer immunology, showcasing their potential roles in phenotypic screening and cancer therapeutics. Despite advancements, the study notes ongoing challenges in translating phenomics research to clinical applications, suggesting that enhanced global partnerships and technological integration are essential. This analysis offers valuable perspectives for future research and highlights phenomics' transformative potential in precision oncology, advocating for its role in advancing cancer diagnosis, treatment, and prevention.
    Keywords:  DP T cells; Multi-omics integration; NK cells; Phenomics; Phenotypic screening; Precision medicine; Tumor heterogeneity
    DOI:  https://doi.org/10.1007/s12672-024-01710-w
  38. Front Neurol. 2024 ;15 1510729
    The application of artificial intelligence in diagnosis of Alzheimer's disease: a bibliometric analysis.
    Xiaoqiong An, Jun He, Bin Bi, Gang Wu, Jianwei Xu, Wenfeng Yu, Zhenkui Ren.
      Alzheimer's disease (AD) is a neurodegenerative disorder that severely impacts cognitive function, posing significant physical and psychological burdens on patients and substantial economic challenges to families and society, particularly in aging populations where its prevalence is rising. Current diagnostic and therapeutic strategies, including pharmacological treatments and non-pharmacological interventions, exhibit considerable limitations in early diagnosis, etiological treatment, and disease management. This study aims to investigate the application of artificial intelligence (AI) in the early diagnosis and progression monitoring of AD through a bibliometric analysis of relevant literature. A systematic search in the Web of Science Core Collection identified 530 publications related to AI and AD, consisting of 361 original research articles and 169 review articles, with a notable increase in annual publication rates, particularly between 2019 and 2024. The United States and China emerged as leading contributors, emphasizing the importance of international collaboration. Institutional analysis revealed that Harvard University and Indiana University System are at the forefront, highlighting the role of academic institutions in fostering interdisciplinary research. Furthermore, the Journal of Alzheimer's Disease was identified as the most influential publication outlet. Key highly cited papers provided essential theoretical foundations for ongoing research. This study underscores the growing relevance of AI in AD research and suggests promising avenues for future investigations, particularly in enhancing diagnostic accuracy and therapeutic strategies through advanced data analytics and machine learning techniques.
    Keywords:  Alzheimer’s disease; Bibliometrix; CiteSpace; VOSviewer; artificial intelligence
    DOI:  https://doi.org/10.3389/fneur.2024.1510729
  39. Int J Nurs Sci. 2024 Nov;11(5): 571-577
    Advances in applying somatosensory interaction technology in geriatric care: A bibliometric analysis.
    Changle Pei, Weibo Lyu, Jingxia Liu, Yan Wang, Wenjia Ye, Zhou Zhou, Kangyao Cheng.
       Objectives: Somatosensory Interaction Technology (SIT) is used in various aspects of geriatric care. We aimed to conduct a bibliometric analysis to summarize relevant publications and visualize publication characteristics, current hotspots, and development trends, thereby inspiring subsequent researches.
    Methods: We searched the Web of Science Core Collection database for publications on the application of SIT in geriatric care. Bibliometric visualization and clustering analysis were performed using VOSviewer V1.6.18 Software, while keywords burst detection analysis was conducted with CiteSpace 6.1.R6 Software.
    Results: After screening, a total of 1,019 publications were included. The number of publications on SIT in geriatric care is gradually increasing, exhibiting a rapid growth rate. The United States, Canada, and Australia led in terms of publication volume. Keyword clustering analysis identified major research hotspots: crisis warning, somatic abilities, rehabilitation training and psychosocial support. Initial studies primarily explored themes such as recovery, movement, systems, and later shifted towards gait analysis, muscle strength, parameters, and home-based care. More recently, research themes have evolved to dementia, machine learning, and gamification.
    Conclusions: SIT is innovative for promoting active aging, advancing intelligent healthcare, and elevating the daily quality of life for older adults in clinical and domestic settings. Applications of SIT can be categorized into early warning systems for crises, detailed analyses of physical conditions, rehabilitation enhancement, and support for psychosocial health. Research trends have transitioned from whole-body recognition to precise feedback, from a focus on physical health to mental health, and from technical feasibility to user-friendliness. Future research should focus on developing accessible and user-friendly devices, fostering interdisciplinary collaborations for innovation, expanding research to address both the physical and mental health needs of diverse older adults, and integrating emerging technologies to enhance data precision and accelerate the development of intelligent platforms.
    Keywords:  Bibliometrics; Data visualization; Geriatric care; Health management; Review; Somatosensory interaction technology
    DOI:  https://doi.org/10.1016/j.ijnss.2024.10.009
  40. J Orthop Surg Res. 2024 Dec 19. 19(1): 853
    Deciphering the past status and future tendency: a comprehensive scientometric study on developmental dysplasia of the hip.
    Boshen Shu, Shufeng Zhang, Jian Gao, Lin Wang, Xiaohui Wang.
       BACKGROUND: Developmental dysplasia of the hip is a common musculoskeletal disorder in newborns and young children, attracting considerable controversy. The purpose of the present study was to analyze the research trends and hotspots over the past three decades in this field.
    METHODS: All related publications were collected from the Web of Science Core Collection from 1994 to 2023. Of these, characteristics of the top 50 cited articles for each decade (1994-2003, 2004-2013 and 2014-2023) were evaluated in detail. Visualized studies were operated via VOSviewer. GraphPad Prism and Microsoft Excel were used to perform statistical analysis. The characteristic of the present study is a cross-sectional study.
    RESULTS: In total, 1,300 publications with 19,815 citations from 1994 to 2023 were selected. The number of publications increased significantly during the past three decades, from 23 in 1994 to 132 in 2023 (P < 0.0001). Studies with collaboration among institutions have raised significantly over time (P < 0.0001). The United States was the leading country to the top 50 publications in each decade. Publications with evidence level IV led the way every ten years. Visualized co-occurrence analysis clustered the keywords into four clusters: hip arthroplasty, congenital dislocation, ultrasound diagnosis and developmental dysplasia of the hip.
    CONCLUSIONS: This study analyzed the global tendency and collaborations on developmental dysplasia of the hip over the past three decades. Even though the research trend has evolved to be collaborative with more multi-institutional publications and authors, studies with high evidence levels are still missing.
    Keywords:  Collaboration; Congenital hip dislocation; Developmental dysplasia of the hip; Scientometrics; Tendency; Visualized study
    DOI:  https://doi.org/10.1186/s13018-024-05358-8
  41. Quant Imaging Med Surg. 2024 Dec 05. 14(12): 8734-8757
    Trends of mapping knowledge structure and themes of cancer sonodynamic therapy: a text-mining study.
    Haiyang Wu, Kunming Cheng, Zaijie Sun, Yanqiu Lu, Qiang Guo, Cheng Li.
       Background: Sonodynamic therapy (SDT) is a non-invasive cancer treatment technique stemming from photodynamic therapy (PDT) and has garnered escalated interest among researchers in recent years. Numerous aspects of cancer SDT remain contentious, and the global research trajectory within this domain remains insufficiently explored. This study seeks to delineate the comprehensive knowledge framework, developmental trends, and pivotal research focal points concerning cancer SDT.
    Methods: The study retrieved documents on cancer SDT from the Web of Science Core Collection (WoSCC) database spanning from 1 January 2000 to 7 December 2023. Bibliometric visualization was carried out through the utilization of CiteSpace 6.2 R6, VOSviewer 1.6.20, and an online analytical platform. Several bibliometric techniques including co-authorship, co-citation, co-occurrence, cluster, as well as burst analysis were used.
    Results: A total of 672 publications including 603 articles and 69 reviews were included. The annual publication count exhibited a steady increase over time, notably experiencing a surge, particularly in recent years. In terms of contributors, China has maintained its prominent position with the highest outputs and the most financial support. Chinese Academy of Sciences contributed the most articles. Materials Science was the most investigated research areas. Breast cancer emerged as the most extensively studied tumor, succeeded by sarcoma, hepatocellular carcinoma, melanoma, pancreatic cancer, glioma. According to co-cited references, "harnessing nanomaterial", "sonodynamic precision tumor therapy" and "metal-organic framework" denote the current and emerging research focuses within the field. In tandem with the results from keywords co-occurrence and burst, we identified the following research topics including mechanism of induced cell death (ferroptosis, immunogenic cell death), nano-related research (nanoplatform, nanozymes, nanomaterials, nanosheets, metal-organic frameworks (MOFs), nanocomposites, nanoparticles, nanosonosensitizers, liposomes, nanocarriers), combination therapies (chemodynamic therapy, immunotherapy, radiotherapy, photothermal therapy), and tumor microenvironment (hypoxia, singlet oxygen, oxidative stress), that may remain the research hotspots and receive sustained attention in the near future.
    Conclusions: For the first time, this bibliometric analysis not only presents a comprehensive portrayal of the knowledge framework, but also delineates shifts in research focal points related to cancer SDT within the last two decades. This systematic summarization offers a comprehensive and lucid comprehension of cancer SDT, providing valuable insights for further investigations in this domain.
    Keywords:  Cancer; CiteSpace; VOSviewer; bibliometrics; sonodynamic therapy (SDT)
    DOI:  https://doi.org/10.21037/qims-24-128
  42. PLoS One. 2024 ;19(12): e0313268
    Breaking down the relationship between disruption scores and citation counts.
    Mingtang Li, Giacomo Livan, Simone Righi.
      The emergence of the disruption score provides a new perspective that differs from traditional metrics of citations and novelty in research evaluation. Motivated by current studies on the differences among these metrics, we examine the relationship between disruption scores and citation counts. Intuitively, one would expect disruptive scientific work to be rewarded by high volumes of citations and, symmetrically, impactful work to also be disruptive. A number of recent studies have instead shown that such intuition is often at odds with reality. In this paper, we break down the relationship between impact and disruption with a detailed correlation analysis in two large data sets of publications in Computer Science and Physics. We find that highly disruptive papers tend to receive a higher number of citations than average. Contrastingly, the opposite is not true, as we do not find highly cited papers to be particularly disruptive. Notably, these results qualitatively hold even within individual scientific careers, as we find that-on average-an author's most disruptive work tends to be well cited, whereas their most cited work does not tend to be disruptive. We discuss the implications of our findings in the context of academic evaluation systems, and show how they can contribute to reconcile seemingly contradictory results in the literature.
    DOI:  https://doi.org/10.1371/journal.pone.0313268
  43. Asian J Surg. 2024 Dec 14. pii: S1015-9584(24)02887-2. [Epub ahead of print]
    A bibliometric analysis of preoperative fasting and fluid management: Trends and advances from 2004 to 2023.
    Yongbo Duan, Yujing Song, Zhongjie Xiao, Wenjun Yan.
      
    Keywords:  Bibliometric analysis; Fluid management; Perioperative care; Preoperative fasting; Ultrasound assessment
    DOI:  https://doi.org/10.1016/j.asjsur.2024.11.238
  44. Health Info Libr J. 2024 Dec 16.
    Government document citations in top nursing journals: A bibliometric analysis.
    Andrew Dudash, Stephen Woods, Kathleen Phillips.
       INTRODUCTION: Citation analysis studies the use of citations found in various types of publications, including the use of government information, and can provide insight into research utilisation in nursing literature.
    METHOD: Using citation analysis, this study examines the use, prevalence and jurisdiction of government information use among seven nursing research journals based on ranking criteria. Government information citations were identified across three types of articles: editorials, reviews and research articles.
    RESULTS: Nearly two-thirds of the articles in this study cite some form of government information, and the average percentage of government citations is 5.38 of all citations. Government information was identified from national governments, inter-governmental organizations and state and regional governments.
    DISCUSSION: Understanding the use, prevalence and jurisdiction of government information informs health information professionals allowing them to engage with nursing students and researchers about this important type of information and the types of articles that use government information.
    CONCLUSION: Nursing researchers frequently cite government information in their work. This has implications for librarians, nursing researchers and health professionals. Understanding the intersection of government information and nursing research should inform future practice in evidence-based nursing research and nursing education.
    Keywords:  bibliometrics; grey literature; nursing literature; scholarly communication
    DOI:  https://doi.org/10.1111/hir.12560
  45. Curr Med Res Opin. 2024 Dec 17. 1-12
    Citation patterns of Cochrane Reviews and other systematic reviews: a bibliometric analysis.
    Louise Olsbro Rosengaard, Mikkel Zola Andersen, Jacob Rosenberg, Siv Fonnes.
       BACKGROUND: The number of systematic reviews is increasing rapidly. Several methodologies exist for systematic reviews. Cochrane Reviews follow distinct methods to ensure they provide the most reliable and robust evidence, ideally based on rigorous evaluations of randomized controlled trials and other high-quality studies. We aimed to examine the difference in citation patterns of Cochrane Reviews and other systematic reviews.
    METHODS: We conducted a bibliometric analysis of systematic reviews indexed in PubMed from 1993 to 2022. We collected data on citations from The Lens from 1993 to 2023, thus having at least one-year follow-up on citations. The reviews were linked through their PubMed identifier. Comparisons between the Cochrane Reviews and other systematic reviews included total citations per review, reviews with zero citations, and the time window within which they receive citations.
    RESULTS: We included 10,086 Cochrane Reviews and 231,074 other systematic reviews. Other systematic reviews received significantly more citations than Cochrane Reviews from 1993 to 2007. From 1993 - 1997, the median difference was 80 citations [95% CI 79.6-80.4]. From 2008 and forward, the overall number of citations was similar between Cochrane Reviews and other systematic reviews (2018-2022: median difference 5 [95% CI 4.9-5.1] in favor of Cochrane Reviews; p = 0.83). Systematic reviews with zero citations were rare in both groups, but it was observed more often among other systematic reviews than Cochrane Reviews. Over the last 30 years, the time window in which all reviews received citations narrowed.
    CONCLUSION: In recent years, Cochrane Reviews and other systematic reviews had similar citation patterns, but other systematic reviews received more citations from 1993 to 2007. Other systematic reviews were more often never cited than Cochrane Reviews, and potentially wasted. The time window in which systematic reviews received citations has been progressively decreasing, possibly indicating a trend toward quicker recognition and uptake of these reviews within the academic community. Cochrane reviews aim to provide robust evidence, but this is not reflected in the citation metrics compared to other systematic reviews.
    Keywords:  Bibliometrics; Citations; Cochrane systematic reviews; Evidence-based practice; Research waste
    DOI:  https://doi.org/10.1080/03007995.2024.2442045
  46. Water Sci Technol. 2024 Dec;90(11): 3076-3110
    Treated greywater as a novel water resource: The perspective of greywater treatment for reuse from a bibliometric analysis.
    Diana Yánez, Lidia Carolina Espinoza, Ignacio Vargas, Julio Romero, María Jesús Aguirre, Roxana Arce, Esteban Quijada-Maldonado, Ricardo Abejon.
      The current global water crisis has prompted research into technologies that can reuse different water resources to mitigate water scarcity. The use of treated greywater can be proposed to provide additional water resources. By reusing this water in different applications, this water crisis can be mitigated at the local scale. This study presents a bibliometric analysis to assess the state of the art of greywater treatment and its reuse technologies. This analysis is based on the scientific literature published until 2023 in Scopus regarding greywater treatment and 1,024 documents were found. The results showed a clear exponential increase in the accumulated number of publications in this topic, which was spurred during the mid-1990s. The most prolific country was the United States, while China, the other typical scientific superpower in most fields, occupied the sixth position in the ranking. Environmental Sciences was the knowledge subject with more documents, followed by Engineering and Chemical Engineering. The bibliometric study was complemented using SciMAT to create bibliometric networks that represent the dynamic evolution of the themes. The most important themes were identified, among which three key points stand out: greywater characterization, technologies for greywater treatment, and water management, including the reuse of treated greywater.
    Keywords:  bibliometric analysis; greywater; wastewater treatment; water management; water recovery; water reuse
    DOI:  https://doi.org/10.2166/wst.2024.384
  47. Discov Oncol. 2024 Dec 18. 15(1): 772
    Research trends on AI in breast cancer diagnosis, and treatment over two decades.
    Alok Singh, Akanksha Singh, Sudip Bhattacharya.
       OBJECTIVE: Recently, the integration of Artificial Intelligence (AI) has significantly enhanced the diagnostic accuracy in breast cancer screening. This study aims to deliver an extensive review of the advancements in AI for breast cancer diagnosis and prognosis through a bibliometric analysis.
    METHODOLOGY: Therefore, this study gathered pertinent peer-reviewed research articles from the Scopus database, spanning the years 2000 to 2024. These articles were subsequently subjected to quantitative analysis and visualization through the Bibliometrix R package. Ultimately, potential areas for future research challenges were pinpointed.
    RESULTS: This study analyzes the development of Artificial Intelligence (AI) research for breast cancer diagnosis and prognosis from 2000 to 2024, based on 2678 publications sourced from Scopus. A sharp rise in global publication trends is observed between 2018 and 2023, with 2023 producing 456 papers, indicating intensified academic focus. Leading contributors include ZHENG B, with 36 publications, and institutions like RADBOUD UNIVERSITY MEDICAL CENTER and the IEO EUROPEAN INSTITUTE OF ONCOLOGY IRCCS. The USA leads both in publications (473) and total citations (18,530), followed by India with 289 papers. Co-occurrence analysis shows that "mammography" (3171 occurrences) and "artificial intelligence" (1691 occurrences) are among the most frequent keywords, reflecting core themes. Co-citation network analysis identifies foundational works by authors like Lecun Y. and Simonyan K. in advancing AI applications in breast cancer. Institutional and country-level collaboration analysis reveals the USA's significant partnerships with China, the UK, and Canada, driving the global research agenda in this field.
    CONCLUSION: In conclusion, this bibliometric review underscores the growing influence of AI, particularly deep learning, in breast cancer diagnosis and treatment research from 2000 to 2024. The United States leads the field in publications and collaborations, with India, Spain, and the Netherlands also making significant contributions. Key institutions and journals have driven advancements, with AI applications focusing on improving diagnostic imaging and early detection. However, challenges like data limitations, regulatory hurdles, and unequal global collaboration persist, requiring further interdisciplinary efforts to enhance AI integration in clinical practice.
    Keywords:  Breast cancer; Cancer diagnosis; Cancer treatment; Generative AI
    DOI:  https://doi.org/10.1007/s12672-024-01671-0
  48. Front Med (Lausanne). 2024 ;11 1522574
    Corrigendum: A bibliometric analysis of interstitial cells of Cajal research.
    Pengyu Li, Yadan Xiao, Lan Zhou, Xuyuan Zhang, Yin Xu, Xiaojuan Wang, Menglong Zou, Xuan Guo.
      [This corrects the article DOI: 10.3389/fmed.2024.1391545.].
    Keywords:  CiteSpace; VOSviewer; bibliometrics; interstitial cells of Cajal; visualization
    DOI:  https://doi.org/10.3389/fmed.2024.1522574
  49. J Gastrointest Cancer. 2024 Dec 19. 56(1): 34
    Gender, Race, and Regional Disparities in Leading Authorships of Gastroenterology and Hepatology Randomized Controlled Trials.
    Subhash Chander, Fnu Sorath, Yaqub Nadeem Mohammed, Om Parkash, Fnu Sadarat, Abhi Chand Lohana, Sheena Shiwlani.
       BACKGROUND AND AIMS: To investigate gender, racial, ethnic, and regional disparities in first and senior authorship positions in gastroenterology/hepatology-related randomised controlled trials (RCT).
    METHOD: Retrospective bibliometric analysis of PubMed-indexed RCTs published between January 2000 to December 2022 in leading journals with an impact factor of at least five.
    RESULTS: 943 RCTs met our inclusion criteria, providing a participant pool of 301 female (15.96%) and 1,585 male (84.04%) authors from 37 countries (70% high-income countries). Despite a significant increase in the proportion of female authors in first and senior authorship positions between 2000 and 2022 (p<0.001), females were grossly underrepresented in both authorship positions, with a male-to-female ratio of 4.45 and 6.37, respectively. The male-to-female ratio was highest among Asian authors (7.79) than among White (4.22), Hispanic (1.44), and Black (1) authors in the first authorship position. In contrast, the male-to-female ratio was similar for Asian (6.2) and White (6.67) authors in the senior authorship position, with a low underlying frequency of Hispanic and Black female authors.
    CONCLUSION: Despite significant improvements in gender, racial and ethnic representation in first and senior authorship of gastroenterology/hepatology-related RCTs published in high-impact journals, progress toward parity remains slow. Targeted interventions to improve author diversity are warranted.
    Keywords:  Authorship; Gender; Income; Racial; Regional
    DOI:  https://doi.org/10.1007/s12029-024-01161-0
  50. Plants (Basel). 2024 Nov 22. pii: 3285. [Epub ahead of print]13(23):
    Research Progress and Hotspots Analysis of Apoplastic Barriers in the Roots of Plants Based on Bibliometrics from 2003 to 2023.
    Chongyuan Qin, Ruoqi Li, Zhuoran Tan, Jingnan Zhang, Yuyang Sun, Jinji Han, Xiaoxia Deng, Fei Wang, Qingjie Yang, Jinghong Wang, Jixiang Lin.
      The apoplastic barriers, composed of Casparian strip (CS) and suberin lamellae (SL), are integral to the regulation of water and plant nutrient uptake in plants, as well as their resilience to abiotic stresses. This study systematically examines the research developments and emerging trends in this field from 2003 to 2023, utilizing bibliometric tools such as Web of Science, CiteSpace, and VOSviewer to analyze a dataset of 642 publications. This paper reviews the cooperation of different countries, institutions, and scholars in apoplastic barriers research based on cooperative network analysis. In the field, China has the highest number of publications, the University of Bolton has the highest number of publications, and Niko Geldner is the author with the maximum number of publications. Notably, 27 publications were identified as highly cited, with their research primarily focusing on (1) genes, proteins, enzymes, and hormones regulating the formation of apoplastic barriers; (2) the influence of adversity stress on apoplastic barriers; (3) the chemical components of apoplastic barriers; (4) the evaluations of research progress on apoplastic barriers. Combined with the keyword co-occurrence network diagram, it is proposed that future research directions in this field should be as follows: (1) physiological functions of apoplastic barriers in plant root; (2) differences in the formation of apoplastic barriers with different root systems; (3) methods to promote apoplastic barriers formation; and (4) application of molecular biology techniques. The present study provides a further understanding of the trends in apoplastic barriers, and the data analyzed can be used as a guide for future research directions.
    Keywords:  CiteSpace; apoplastic barriers; bibliometrics; casparian strip; suberin lamellae
    DOI:  https://doi.org/10.3390/plants13233285
  51. Stress Health. 2025 Feb;41(1): e3524
    Global Research on Cyberchondria: Scientometric and Visual Analysis From 2003 to 2022.
    Caner Baysan, Seher Palanbek Yavaş.
      This study aims to summarise the research themes, hotspots, and boundaries in the field of cyberchondria using scientometrics and visual analysis methods. Until 31 December 2022, 181 publications (165 articles, 16 reviews) were identified under the topic of 'cyberchondria' in the Web of Science Core Collection database. VOSviewer was used for analysis. It was observed that publications related to cyberchondria have rapidly developed into a research area in the last 4 years, constituting 79.0% (n = 143) of the total publications. The most common co-occurring keywords are 'cyberchondria', 'health anxiety', and 'COVID-19'. Clusters representing three different themes were obtained by conducting co-occurring keyword analysis. The first and largest cluster comprises 'COVID-19', 'anxiety', and 'internet addiction', the second cluster includes 'cyberchondria' and 'health anxiety', and the third cluster centres around 'health information' and 'health education' keywords. This study has mapped out the information landscape of cyberchondria research over the past 20 years using scientometric and visual analysis methods. The significant increase in recent years indicates a diversification and continued growth in studies conducted in this field. By presenting the general state of the field, this study provides valuable insights for future research endeavours.
    Keywords:  cyberchondria; health anxiety; scientometrics; voswiever visualised analysis
    DOI:  https://doi.org/10.1002/smi.3524
  52. Am J Chin Med. 2024 Dec 16. 1-25
    Luteolin: A Comprehensive and Visualized Analysis of Research Hotspots and its Antitumor Mechanisms.
    Jiaxuan Wang, Hao Li, Zhenru Wang, Shanming Ruan.
      The aim of this study was to analyze the research hotspots and mechanisms of luteolin in tumor-related fields using bibliometric and bioinformatic approaches to guide future research. We conducted a comprehensive screening of all articles on luteolin and tumors in Web of Science from 2008 to 2023. The extracted words from these publications were visualized using VOSviewer, Scimago Graphica, and CiteSpace. Public databases were used to collect luteolin and tumor-related targets. GO and KEGG analyses of luteolin antitumor-related genes were performed using Metascape. Protein interaction networks were built with Cytoscape and STRING, identifying hub targets of luteolin in antitumor activity. Subsequently, the binding capacity of luteolin to these hub targets was assessed using molecular docking technology. We found that China dominated this field, the Egyptian Knowledge Bank published the most articles, and Molecules had the highest number of related publications. Recently, network pharmacology, target, traditional Chinese medicine, and nanoparticles have become research hotspots in luteolin's antitumor research. A total of 483 overlapping genes between luteolin and tumors were identified, and they were closely associated with the cancer-associated pathways, PI3K-Akt, and MAPK signaling pathways. Luteolin forms a complex network of antitumor-related genes, with TP53, TNF, STAT3, AKT1, JUN, IL6, and SRC playing key roles and showing strong binding affinity to luteolin. Computer technology is becoming increasingly integral to the discipline, and future research will focus on more precise antitumor mechanisms and effective clinical applications.
    Keywords:  Anticancer Property; Bibliometrics; Bioinformatics; Hotspots; Luteolin; Mechanisms; Review
    DOI:  https://doi.org/10.1142/S0192415X24500903
  53. Int J Ophthalmol. 2024 ;17(12): 2295-2307
    Artificial intelligence applications in ophthalmic optical coherence tomography: a 12-year bibliometric analysis.
    Ruo-Yu Wang, Si-Yuan Zhu, Xin-Ya Hu, Li Sun, Shao-Chong Zhang, Wei-Hua Yang.
       AIM: To explore the current application and research frontiers of global ophthalmic optical coherence tomography (OCT) imaging artificial intelligence (AI) research.
    METHODS: The citation data were downloaded from the Web of Science Core Collection database (WoSCC) to evaluate the articles in application of AI in ophthalmic OCT published from January 1, 2012 to December 31, 2023. This information was analyzed using CiteSpace 6.2.R2 Advanced software, and high-impact articles were analyzed.
    RESULTS: In general, 877 articles from 65 countries were studied and analyzed, of which 261 were published by the United States and 252 by China. The centrality of the United States is 0.33, the H index is 38, and the H index of two institutions in England reaches 20. Ophthalmology, computer science, and AI are the main disciplines involved. Hot keywords after 2018 include deep learning (DL), AI, macular degeneration, and automatic segmentation.
    CONCLUSION: The annual number of articles on AI applications in ophthalmic OCT has grown rapidly. The United States holds a prominent position. Institutions like the University of California System and the University of London are spearheading advancements. Initial researches centered on the automatic recognition and diagnosis of ocular diseases leveraging traditional machine learning (ML) technology and OCT images. Nowadays, the imaging process algorithm selection has shifted its focus towards DL. Concurrently, optical coherence tomography angiography (OCTA) and computer-aided diagnosis (CAD) have emerged as key areas of contemporary research.
    Keywords:  artificial intelligence; bibliometric analysis; deep learning; optical coherence tomography
    DOI:  https://doi.org/10.18240/ijo.2024.12.19
  54. J Thorac Dis. 2024 Nov 30. 16(11): 7885-7904
    The training in thoracoscopic surgery: a comparative study and bibliometric analysis.
    Shaojin Zhu, Toni Lerut, Xiaogan Jiang.
       Background: Thoracoscopic surgery training is a critical area in medical education, and understanding the trends and focus areas in this field is vital for enhancing training programs and guiding future research. The study aimed to retrospectively analyze the effects of two training methods for new students in actual thoracoscopic surgery and to summarize the development and trends of research in thoracoscopic surgery training through a bibliometric analysis of the relevant academic literature.
    Methods: 72 cases of thoracic surgery students were retrospectively analyzed and divided into observation group (n=36) and control group (n=36) according to different periods. The trainees in the control group underwent conventional instruction via book-based mapping of the chest anatomy, and those in the observational group were educated via preoperative interpretation of chest computed tomography (CT) 3D reconstruction combined with review of the related surgical videos and thoracoscopic procedures. The efficacies of these two methods were evaluated and assessed upon completion of the training session. Additionally, a comprehensive literature search was conducted on the Web of Science Core Collection (WoSCC) on May 27, 2024. VOSviewer, CiteSpace and the R-based online toolkit Shiny were employed for the bibliometric analysis, which facilitated the visualization of collaborations, keyword co-occurrences, and emerging research trends.
    Results: The intraoperative performance of the trainees in the observational group was significantly better than that of those in the control group in practice, including positioning and directing the shaft of the thoracoscope, interference with other devices, conversion of the near and far views, correct orientation of the lens, ensuring the operating point projected at the center of the video, cooperation with the operator, image clarity, stability of the video, the angle of the video camera lens and adjustment of the lens angle, among others (all P values <0.05). A total of 956 articles published from 1992 to 2024 were included in the study. These publications were contributed by 5,217 authors from 2,603 institutions across 289 countries. Hansen Henrik Jessen was identified as one of the most prolific authors. The University of Copenhagen emerged as the most productive institution. The journal Annals of Thoracic Surgery was identified as a prominent publisher in this field. The keyword "experience" was the most frequently occurring term.
    Conclusions: Preoperative interpretation of chest CT 3D reconstruction combined with the review of surgical videos for training the camera holders in thoracic surgery can greatly improve the performance and accelerate the training of the assistant during the procedure. Additionally, this bibliometric analysis highlight the importance of clinical experience and the integration of new surgical techniques and training methods. Future research should focus on advanced training methods and simulation-based learning to accelerate skill acquisition and proficiency.
    Keywords:  Thoracic surgery; bibliometrics; education; thoracoscopy
    DOI:  https://doi.org/10.21037/jtd-24-1913
  55. BMC Musculoskelet Disord. 2024 Dec 19. 25(1): 1029
    High impact works on stem cell transplantation in intervertebral disc degeneration.
    Xiaofeng Chen, Hao Li, Baoci Huang, Jiajian Ruan, Xi Li, Qian Li.
       BACKGROUND: Low back pain is a major disorder that causes disability and is strongly associated with intervertebral disc degeneration (IDD). Because of the limitations of contemporary interventions, stem cell transplantation (SCT) has been increasingly used to regenerate degenerative discs. Nevertheless, analyses of high-impact papers in this field are rare. This study aimed to determine and analyze the 100 highest-cited documents on SCT in IDD.
    METHODS: The 100 highest-cited documents were retrieved from the Web of Science (WoS) database. Descriptive statistics were calculated and correlation analysis was conducted to determine the relationship between WoS citations, the Altmetric Attention Score (AAS), and Dimensions citations.
    RESULTS: The citation counts of the top 100 most cited papers ranged from 13 to 372. These studies were conducted in 17 countries and were published in 48 journals between 2003 and 2021. The top three contributing countries were the China (31), United States (22), and Japan (14). Bone marrow-derived stem cells were the most common type of stem cells (70.00%), followed by adipose-derived stem cells (13.75%), and nucleus pulposus-derived stem cells (7.50). Rabbit was the most studied species (41.25%), followed by rat (21.25%), human (13.75%), sheep (8.75%), dog (8.75%), and pig (6.25%). Tokai University School of Medicine (11) had the largest number of documents, followed by The University of Hong Kong (8), and Southeast University (4). Sakai D (10) was the most fruitful author, followed by Cheung KMC (6), Melrose J (3), Pettine K (3), Lotz JC (3), and Murphy MB (3). We observed a very high correlation between the WoS and Dimensions citations (p < 0.001, r = 0.994).
    CONCLUSIONS: This study highlights the highest impact works on SCT in IDD, thereby providing a deeper understanding of the historical works related to SCT in IDD, as well as benefits for future studies in this field.
    Keywords:  Cell transplantation; Intervertebral disc degeneration; Progenitor cell; Stem cell; Stromal cell
    DOI:  https://doi.org/10.1186/s12891-024-08131-4
  56. Front Plant Sci. 2024 ;15 1457826
    Bibliometric analysis of research trends in agricultural soil organic carbon components from 2000 to 2023.
    Guolong Ge, Xuanyi Chen, Hexiao Ma, Xiangqian Zhang, Jingjing Shi, Xiaoxiang Wang, Xiaoqing Zhao, Manxiu Wang, Feng Xian, Zhanyuan Lu, Yuchen Cheng.
      Soil organic carbon is a vital component of the soil carbon pool. Investigation of its composition and dynamics is crucial for enhancing carbon sequestration in soils and for stabilizing the global carbon cycle. In recent years, considerable research has focused on the interactions between soil organic carbon components and their responses to varied land use and agricultural practices. However, the mechanism of soil organic carbon sequestration and response characteristics of soil organic carbon components to soil carbon pools are still subject to some debate. To the best of our knowledge, no researchers have used bibliometric analyses to explore the field of soil organic carbon components. This study thus involved the use of bibliometric techniques to identify research hotspots in the study of organic carbon components over the last 23 years and future trends in research development. Specifically, we performed a comprehensive literature review of 607 documents pertaining to organic carbon components using the Web of Science database, covering the period from 2000 to 2023. Employing CiteSpace, we visualized and analyzed the data across national, institutional, disciplinary, and keyword dimensions. In this study, we conducted a comprehensive, systematic, and quantitative analysis of publications pertaining to organic carbon component research. The results indicate that researchers in the United States and China have substantially influenced the study of soil organic carbon components. Since 2000, the United States has pioneered the study of soil organic carbon components, establishing a foundational role in this field of research. Meanwhile, China leads with the largest number of publications and the most diverse research directions in this field. Among the institutions involved in such research, the University of Chinese Academy of Sciences has the highest number of publications. The investigation of soil organic carbon components within agricultural systems is inherently multidisciplinary, with the most comprehensive research being performed within the soil sciences discipline. At present, the focal areas of research on soil organic carbon components predominantly revolve around the impacts of straw return to fields, varying land-use changes, restoration of vegetation, and the reciprocal effects of soil organic carbon components on the restoration of vegetation. The findings of this work highlight the research hotspots within the field of soil organic carbon components and the emerging trends within this field. This work offers novel insights into the dynamics of soil organic carbon components, potentially guiding future studies in this vital field.
    Keywords:  CiteSpace; bibliometrics; land-use pattern; soil organic carbon component; visualization analysis
    DOI:  https://doi.org/10.3389/fpls.2024.1457826
  57. Front Microbiol. 2024 ;15 1453755
    Probiotic effects on skin health: comprehensive visual analysis and perspectives.
    Kexin Deng, Xiaofei Fan, Zhigen Yuan, Dian Li.
       Background: Bacteria play a crucial role in maintaining the health of human skin. Research has demonstrated that probiotics present notable benefits for extraintestinal organs. Despite the extensive research on the impact of probiotics on skin health, there is a notable absence of regulatory frameworks governing their external application, with no approval from the FDA for any probiotic products for external use. The aim of this study is to offer a thorough summary of the research status in the field since 2000 and project future trends.
    Method: The Web of Science Core Collection and SCI-Expanded index were selected for an extensive search of studies concerning the role of probiotics in skin health since 2000. A total of 1,306 publications were identified. Employing a double-blind method, two subsets of literature were scrutinized and subsequently combined for analysis. Using CiteSpace, this research explored key aspects such as primary countries, institutions, authors, journals, trending topics, research frontiers, and emerging patterns in research related to application of probiotic for skin health.
    Result: This article included 709 research papers. The number of published papers has shown a rapid increase. The United States had the highest number of research papers (128), and Canada had the highest intermediate centrality (0.23). The University of California System emerged as the most prolific institution. Huang, Chun-Ming has published the most articles, and his research is at the forefront among those prolific authors. Twelve clusters were identified, with cluster #0 skin microbiota, #3 mechanisms, and #8 antimicrobial being the most recent. As for the hot topic, "diversity," "health," "skin microbiome," "oxidative stress," "microbiota," and "antioxidants" have been at the forefront of the current field. The overall research trend has shifted from clinical trials to mechanistic exploration and from oral treatments to external applications, with the research level moving from general categories to specific strains.
    Conclusion: This paper summarized and visualized academic achievements in the field of probiotic application for skin health using CiteSpace and VOSviewer, offering a systematic and comprehensive perspective, along with a longitudinal overview of this research field.
    Keywords:  bacteria; bibliometrics; prebiotics; probiotics; skin
    DOI:  https://doi.org/10.3389/fmicb.2024.1453755
  58. Plants (Basel). 2024 Nov 29. pii: 3358. [Epub ahead of print]13(23):
    Environmental Indicator Plants in Mountain Forests: A Review.
    Lucian Dinca, Vlad Crisan, Gruita Ienasoiu, Gabriel Murariu, Romana Drasovean.
      Plant indicators are important in studies related to the environment, and mountain forests are rich in such plants. We conducted this study using the Web of Science Core Collection tools and the VOSviewer program combined with a classic review, based on the specialty literature. The topic of indicator plants in mountain forests has been (the first article published in a prestigious journal dates back to 1980) and remains relevant (after 2015, between 40 and 60 articles were published annually), with the total number of publications found being 665 articles and 22 review articles. These publications were authored by researchers from 96 countries, the most representative being the USA, China, and Germany (which also have large areas of mountain forests), and were published in 306 journals, with the most important being Ecological Indicators, Forest Ecology and Management, Forests, Journal of Vegetation Science, and Plant Ecology. They belong to the main scientific fields of Ecology, Forestry, Plant Sciences, and Environmental Sciences. The most frequently used keywords are vegetation, diversity, biodiversity, and forests. Their evolution over the past decade shows that the focus has shifted from keywords specific to this topic to those related to biodiversity and conservation, and more recently to climate change. Indicator plants in mountain forests are extremely varied but can be used successfully in the monitoring activity. Climatic conditions or human interventions lead to the dynamic of these indicator plants.
    Keywords:  VOSviewer; articles; bibliometric review; indicator plants; journals; keywords
    DOI:  https://doi.org/10.3390/plants13233358
  59. Front Oral Health. 2024 ;5 1494435
    Evolution of scientific productivity in dentistry: tracking postgraduate publications at a Peruvian university.
    Cesar D Rojas-Senador, María Claudia Garcés-Elías, Roberto A León-Manco.
       Introduction: Scientific production indicators help universities quantitatively and qualitatively assess postgraduate students' publications and contribute to the optimization of research processes. This study aimed to determine the frequency of publication in scientific journals of the documents submitted by postgraduate dentistry students to obtain a second professional specialty title and master's and doctoral degrees at a private Peruvian university over seven years.
    Materials and methods: A cross-sectional study was conducted, considering the population and the records of documents submitted to obtain the second professional specialty title and the master's and doctoral degrees in dentistry at a private Peruvian university, published in its institutional repository from 2017 to 2023. The primary outcome was publication in scientific journals, and the covariates were the year of formal submission of the document, postgraduate level, modality of document preparation, area of dentistry specialty according to the American Dental Association, year of publication, international indexing, impact factor (IF), and quartile. A descriptive analysis was performed to obtain absolute and relative frequencies.
    Results: Between 2017 and 2023, out of 322 documents submitted to receive the second professional specialty title and the master's and doctoral degrees published in the institutional repository, 72 were published in scientific journals. Of these, 81.94% (n = 59) were published in an internationally indexed scientific journal, with 13.56% (n = 8) published in a journal with an IF≥2 and 10.18% (n = 6) in a Q1 category journal.
    Discussion: In low-income countries, the nexus between education and scientific output is multifaceted. While education serves as a critical catalyst, numerous challenges constrain the expansion of research. These nations contribute a mere 2% of global scientific production, despite confronting significant public health issues, underscoring a notable discrepancy between educational attainment and research productivity. The disparities in scientific output across universities in Latin America, Asia, and Europe are shaped by a confluence of cultural and economic determinants. In conclusion, 22.36% of the documents submitted to obtain the second professional specialty title and the master's and doctoral degrees by postgraduate dentistry students at a private Peruvian university over seven years were published in scientific journals.
    Keywords:  academic dissertation; dental; education; graduate; students; universities
    DOI:  https://doi.org/10.3389/froh.2024.1494435
  60. J Thorac Dis. 2024 Nov 30. 16(11): 8156-8157
    Erratum: The quality of life of patients with chronic obstructive pulmonary disease: a bibliometric analysis.
    Editorial Office
      [This corrects the article DOI: 10.21037/jtd-24-591.].
    DOI:  https://doi.org/10.21037/jtd-2024-06
  61. Int J Surg. 2024 Dec 20.
    Artificial intelligence in surgery: evolution, trends, and future directions.
    Huiyang Li, Zhuoqi Han, Haixiao Wu, Elmar R Musaev, Yile Lin, Shu Li, Alexander D Makatsariya, Vladimir P Chekhonin, Wenjuan Ma, Chao Zhang.
      Artificial intelligence (AI) is significantly transforming surgery by enhancing precision, decision-making, and patient outcomes. This bibliometric analysis examines AI's impact on surgery, highlighting research trends, key contributors, and evolving themes from 1998 to 2024. Utilizing data from the Web of Science Core Collection and analyzed through the Bibliometrix tool, the study reviews publication trends, author impact, institutional contributions, country-specific research activities, and keyword frequency. A total of 821 articles were examined, revealing a 14.53% annual growth rate in publications, increasing from one in 1998 to 328 in 2023. Influential contributors include 10 157 authors, notably HASHIMOTO DA and ITO M. Prominent institutions such as Harvard University and Stanford University, along with leading countries like the USA and China, play major roles in this field. High-frequency keywords identify core research areas: surgery, artificial intelligence, classification, diagnosis, and outcomes. Thematic evolution shows a shift from foundational concepts to advanced applications and interdisciplinary collaborations. AI integration into surgical practices is revolutionizing the field, driving advancements in precision, efficiency, and patient care. The study underscores significant research growth, influential contributors, and key trends, emphasizing the importance of continued interdisciplinary collaboration and innovation. Future research should focus on enhancing AI applications, addressing data quality and security challenges, and expanding into diverse surgical contexts to further improve surgical outcomes and patient care. AI in surgery is a rapidly evolving and promising field for innovation, with its full potential reliant on enhanced collaboration across disciplines.
    DOI:  https://doi.org/10.1097/JS9.0000000000002159
  62. Medicine (Baltimore). 2024 Dec 13. 103(50): e40791
    Laboratory biosafety: A visual analysis in the web of science database from 2000 to 2022: A review.
    Sunyun Qi, Siyuan Chen, Dries De Witte, Geert Molenberghs, Qifeng Zhang, Hua Gu, Yanchao Gao.
      To conduct a visual analysis of institutional publications, individual publications and publication keywords in the field of laboratory biosafety using the Web of Science database from 2000 to 2022.VOSviewer 1.6.18 was used to study the relation between paper authors, and CiteSpace 6.1.R6 was used to visualize the collaboration between the paper institutions, the paper keywords and the timeline. The main research institutions included the Centers for Disease Control and Prevention (USA), and the University of Chinese Academy of Sciences (China). The collaboration between the research institutions was limited and dispersed. Each of the main study teams is led by Feldmann Heinz, Peter B. Jahrling, Roger Hewson, and Li Na. Infection, identification, and outbreak are the keywords that appear more often and are also of higher importance in publications. The citation burst of keywords varies over time: outbreak, resistance, and polymerase chain reaction from 2004 to 2012; gene, cells, and Ebola from 2013 to 2017; and spread, safety, coronavirus, and African swine fever from 2018 to 2022. The centralization of research teams and individuals in laboratory biosafety is not conducive to the growth of disciplinary diversity. These publication keywords are mainly align with significant social events, scientific and technological development trends, and national strategic needs. This paper advocates for a more balanced allocation of resources and collaboration opportunities to foster diversity and address emerging challenges in the field of laboratory biosafety.
    DOI:  https://doi.org/10.1097/MD.0000000000040791
  63. Pan Afr Med J. 2024 ;48 182
    Retraction of biomedical publications with Tunisian affiliation: causes, characteristics, and legislation regarding breaches of scientific integrity.
    Amira Maoui.
       Introduction: breaches of research integrity have risen during these years. Tunisia´s stance regarding scientific integrity remains unknown. The aim of our study was to identify the reasons for the retraction of Tunisia-affiliated publications in the biomedical field, to describe the characteristics of these retractions, and to assess the position of Tunisian legislation regarding breaches of research integrity.
    Methods: I compiled up to November 3rd, 2023, and retracted biomedical papers using the PubMed and Retraction Watch databases. For each eligible retracted article, a descriptive study of the collected variables was carried out. These included the reasons for retraction, characteristics related to the article, authors, and journal.
    Results: the search identified 22 eligible publications. Reasons for retraction were categorized into six groups. Plagiarism accounted for 45.5% of cases. The first retraction dated back to 2005, with an average number of retracted publications being 1.22 and a median retraction time of 347 days. Among the retracted publications, 77.3% included a retraction notice. A post-retraction citation was found in 81.3% of cases. None of the retracted articles were written by a single author. An international collaboration was found in 27.3% of cases. Ninety-five point five percent of journals offered open access with 81.8% using a gold open access model. In terms of bibliometrics, eleven articles were published in highly reputed journals.
    Conclusion: Tunisia is not spared from breaches of scientific integrity. The controversies relating to the categories of breaches call for standardization. The legislative framework for this phenomenon also remains to be developed in Tunisia.
    Keywords:  Ethical issue; Tunisia; plagiarism; research misconduct; scientific fraud
    DOI:  https://doi.org/10.11604/pamj.2024.48.182.44793
  64. Int J Hematol Oncol Stem Cell Res. 2024 Oct 01. 18(4): 390-399
    Scientometrics Analysis of Global Researches on Anemia.
    Hedye Khaledi, Fatemeh Makkizadeh, Afsaneh Hazeri.
      Background: Anemia is a condition in which the number of red blood cells or the hemoglobin concentration within them is lower than normal. This study aims to show the intellectual structure of knowledge regarding anemia and gives a comprehensive and up-to-date image of research in this area. Materials and Methods: This is a descriptive-analytical study with a scientometric approach. The PubMed database was searched for research publications indexed under "anemia" including 8484 records between 2011 and 2020. Data were analyzed using Co-word analysis, clustering methods, and strategic diagrams with the help of SPSS and Ucinet 6 software.  Results: The keyword "Anemia Sickle Cell" and two pairs of frequently used keywords, namely "Anemia, Iron *Iron" were the most frequent in the research area. The results shaped the concepts of anemia in 9 clusters. The clusters "Hydroxyurea and sickle cell anemia", "Fetus transfusion", "Management of Thalassemia Major", "Hemolytic Uremic Syndrome", "Management and Control of Anemia", "Chronic Kidney Failure and Anemia", "Hematopoietic Stem Cell Transplantation" are topics that may be emerging or disappearing. The "Thalassemia and blood transfusion" are immature clusters. Conclusion: This study uses co-word networks that indicate important links between keywords of the research areas. Most research approaches are in the therapeutic aspects. Despite the importance of the effect of anemia on all levels of society, including economics, education, and other types of anemia, as well as its impact on learning and mental disorders, these subjects have not been given sufficient consideration.
    Keywords:  Anemia; Bibliometrics; Co-word analysis; PubMed
    DOI:  https://doi.org/10.18502/ijhoscr.v18i4.16763
  65. Adv Clin Exp Med. 2024 Dec 13.
    The only constant in life is change: Summary of the last 4 years of Advances in Clinical and Experimental Medicine.
    Marek Misiak, Donata Kurpas.
      In the last 4 years, the journal Advances in Clinical and Experimental Medicine has made significant strides in adapting to changes in scientific publishing. It has maintained high levels of citations and submitted manuscripts, publishing a considerable number of articles ahead of print releases to minimize wait times. With a solid reputation and a growing base of over 7,000 reviewers, the journal upholds rigorous ethical standards and thorough statistical verification for all manuscripts. Bibliometric indicators showcase the impact of Adv Clin Exp Med, including an increased impact factor, CiteScore, Index Copernicus Value (ICV) and recognition in indexes and bases like Scopus and PubMed Central (PMC). International cooperation support for early-career researchers are key focuses, with efforts to provide guidelines, online meetings, and social media promotion. Various materials for authors prepared by the editorial staff are discussed, including detailed instructions for authors, tips regarding graphical abstracts and choosing a checklist, as well as ethical guidelines, a brochure on the rules of statistical analysis and data presentation, and technical requirements for figures. The journal also emphasizes data sharing, detailed procedures for errata and retractions, and clear policies concerning the use of artificial intelligence (AI) tools. Calls for submissions show authors the optimal direction for creating original, innovative scientific papers. Financing from the Polish Ministry of Science and Higher Education ensures the financial stability of the journal. By adapting to the evolving landscape of scientific communication, Adv Clin Exp Med remains dedicated to facilitating open access publishing and disseminating high-quality medical research to its readers.
    Keywords:  ahead of print; bibliometrics; early-career researchers; research ethics; scientific journal
    DOI:  https://doi.org/10.17219/acem/197093
  66. J Am Acad Orthop Surg. 2024 Dec 13.
    Relative Citation Ratio Among Pediatric Orthopaedic Surgeons: Examining the Factors Associated With Higher Scores.
    Scott J Halperin, Aidan Gilson, Meera M Dhodapkar, Maxwell Prenner, Dominick Tuason, Jonathan N Grauer.
       INTRODUCTION: Academic scholarship is often valued by clinicians, peers, and intuitions. Quantifying the effect of research publications is challenging. Various metrics have been used to assess this. This study aimed to examine the relatively new research metric, relative citation ratio (RCR), introduced by the National Institutes of Health, for pediatric orthopaedic surgeons to establish the benchmarking of research effect within the field and understand the distribution and basis for the use of this metric among pediatric orthopaedic surgeons.
    METHODS: The RCR indices were assessed for members of the Pediatric Orthopaedic Society of North America using the iCite online web service. The mean RCR (mRCR, the yearly average RCR) and weighted RCR (wRCR, the cumulative RCR score) were assessed for each member. This information was used to perform univariate and two multivariate ordinary least squares regressions for the two metrics. Independent variables were physician sex, years since receiving national provider identifier, MD versus DO degree, whether the physician had a PhD, and geographic region of practice (Northeast, Southeast, Midwest, West, and Southwest).
    RESULTS: A total of 770 pediatric orthopaedic physicians were identified. The median [interquartile range] wRCR was 15.6 [4.9 to 54.2], and median mRCR was 1.4 [1.0 to 1.9]. Multivariable squares regression for wRCR showed an independently increased wRCR associated with male sex (39.11), PhD (23.32), years since receiving national provider identifier (4.51), and northeast region (48.44). However, these trends were not notable for mRCR where only southeast region was notable.
    CONCLUSION: Although each has its caveats, both mRCR and wRCR have a place in evaluating an author's publication history and other research metrics. Furthermore, it is important to know the overall research metrics within a field to allow for inter- and intraspecialty comparisons. Understanding RCR is helpful because it allows for new comparisons within and across fields and career lengths.
    DOI:  https://doi.org/10.5435/JAAOS-D-24-00756
  67. Naunyn Schmiedebergs Arch Pharmacol. 2024 Dec 18.
    Scientific, bibliometric and biographical analysis of 71 Jewish and dissident pharmacologists persecuted in Germany between 1933 and 1945.
    Mirja Mispagel, Roland Seifert.
      Naunyn-Schmiedeberg's Archives of Pharmacology, founded in 1873, is the oldest pharmacological journal. This study sheds light on the influence of persecution and expulsion of Jewish and dissident German pharmacologists during the Nazi era (1933-1945) on their scientific work and publication behaviour. The analysis is based on the German-language book 'Verfolgte deutschsprachige Pharmakologen (persecuted German-speaking pharmacologists) 1933-1945' by Trendelenburg and Löffelholz (2008), which contains short biographies of 71 persecuted pharmacologists. We analysed their publication activity from 1900 to 1980, the topics of the publications and the emigration data. Most persecuted pharmacologists emigrated, with two peaks of emigration around 1933 and 1938. Most pharmacologists emigrated to the USA, followed by Great Britain. Five of the scientists who emigrated to Great Britain were elected to the British Pharmacological Society's Pharmacology Hall of Fame, and one of them was a Nobel Laureate. Very few of the emigrated pharmacologists returned to Germany. After the Nazis came to power in 1933, the share of papers by persecuted pharmacologists in Naunyn-Schmiedeberg's Archives of Pharmacology dropped sharply. At around 1936, several of the persecuted pharmacologists began to publish increasingly in the American competitor journal, the Journal of Pharmacology and Experimental Therapeutics. The persecuted pharmacologists who emigrated to Great Britain had a major influence on the British Journal of Pharmacology, founded in 1946, as initially, they accounted for a high proportion of publications. We further analysed the papers published in Naunyn-Schmiedeberg's Archives of Pharmacology by persecuted pharmacologists between 1933 and 1945. About half of these papers were submitted from abroad, indicating that despite the persecution and repression, papers from persecuted pharmacologists previously working at German institutes were still published during this period. Most of the papers by persecuted pharmacologists published from German institutes during this period were published under regime-critical or politically persecuted institute directors. Persecuted pharmacologists covered a huge spectrum of scientific topics, highlighting their immense scientific impact. After World War II, Naunyn-Schmiedeberg's Archives of Pharmacology lost much of its previous thematic diversity for decades. Overall, our analyses highlight the enormous loss to German pharmacology due to the persecution, exclusion and expulsion of 'non-Aryan' pharmacologists. Conversely, pharmacology of the USA and Great Britain benefited greatly from the emigration of distinguished scientists from Germany.
    Keywords:   Naunyn–Schmiedeberg’s Archive of Pharmacology ; National socialism; Persecuted pharmacologists; Publication activity
    DOI:  https://doi.org/10.1007/s00210-024-03645-z
  68. Cureus. 2024 Nov;16(11): e73566
    Challenges and Progress in Neurosurgery: A Comprehensive Assessment of the Landscape in Nepal.
    Ganesh Phayal, Pragya Rijal, Sabrina Muhanna, Ernest Barthelemy, Amrit Chiluwal.
      A large portion of the global population lacks access to essential surgical care, despite surgical conditions contributing significantly to the overall burden of disease worldwide. This burden is heaviest in developing countries like Nepal, where disparities in access to surgery for neurosurgical disorders stem from health system failures including an inadequate neurosurgical workforce, lack of requisite neurosurgical equipment, and challenges in perioperative care. By bibliometric analysis of neurosurgery-related publications in Nepal through PubMed search using the search terms "Neurosurg* AND Nepal", we have found a total of 528 articles with a notable increase in the number of such publications from 14 to 25 between 2015 and 2016, with over 300 published in 2021, 2022, and 2023. Nepal has also seen a drastic increase in neurosurgeon density from 0.166 per 100,000 population in 2016 to 0.377 per 100,000 population in 2023 compared to 0.780 in China, 0.274 in India, 0.130 in Bhutan, and 0.092 per 100,000 population in Bangladesh in 2023. This study underscores the pressing need for enhanced neurosurgical capacity and improved health equity in Nepal.
    Keywords:  global burden of disease; global neurosurgery; lmic; nepal; neurosurgery in nepal; wfns; who
    DOI:  https://doi.org/10.7759/cureus.73566
  69. An Acad Bras Cienc. 2024 Dec 16. pii: S0001-37652024000400101. [Epub ahead of print]96(suppl 2): e202496s2
    Contribution of a special issue on Antarctic research to the AABC impact factor.
    Alexander W A Kellner.
      
    DOI:  https://doi.org/10.1590/0001-3765202496s2
  70. Neurourol Urodyn. 2024 Dec 17.
    Examining Gender Representation in US News and World Report Top 25 Urology Departments: Female Faculty Hold Lower Professorial Levels and Publication Rates Than Male Counterparts.
    Greeshma Venigalla, Sabika Sadiq, Aaron A Gurayah, Nachiketh Soodana-Prakash, Laura Martin, Katherine A Amin, Raveen Syan.
       OBJECTIVES: To examine female representation in US News and World Report (USNWR) top 25 US Urology departments and identify trends of female representation in institutional roles.
    METHODS: Using the 2022 USNWR, we collected data from each institution's websites along with a compared geographically local cohort to evaluate the presence of female residents, female attendings, and professorial levels. First or last author faculty publications numbers were found using PubMed and Scopus in fiscal year 2022.
    RESULTS: The top 25 institutions averaged ~32.3% female residents and 18.7% female attendings, which was not significantly different from the comparison cohort. Of the total publications of fiscal year 2022, female attendings contributed ~14% (p < 0.001), also not significantly different from the comparison cohort. Only 20.4% of listed female attendings in top 25 programs are full Professors, compared to 41.1% of the listed men (p < 0.05). The most common level of female professorship is Assistant Professor (53.4%). Level of female professorship between cohort was significantly different, with female urologists more likely to hold a title of full Professor in the top 25 cohort compared to the nontop 25 cohort regardless of similar publication output (p < 0.05).
    CONCLUSIONS: Female faculty in Urology continue to be underrepresented in the top Urology departments, with significant difference in equitable female professorship appointments between top 25 and nontop 25 departments. Future directions include examining the impact of early mentorship and sponsorship on representation over time.
    Keywords:  barriers; gender equity; physician workforce; underrepresented; women
    DOI:  https://doi.org/10.1002/nau.25639
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