bims-evares Biomed News
on Evaluation of research
Issue of 2025–08–17
sixty-five papers selected by
Thomas Krichel, Open Library Society
  1. A Bibliometric Analysis on Research Trends in Paediatric Epilepsy Treatment From 2005 to 2025.
  2. Achilles Tendon Rupture: A Bibliometric Study.
  3. The Journal of Robotic Surgery at a glance: productivity, impact, and thematic evolution.
  4. Trends and hotspots in global influenza and intestinal flora research based on bibliometrics.
  5. Bibliometric and visual analysis of quercetin in kidney disease from 2000 to 2022.
  6. Visualized analysis of trends and hotspots in global refeeding syndrome: A bibliometric analysis study (2000-2024).
  7. The evolution of the impact of educational background on oral health: A bibliometric and visualized analysis from 2000 to 2024.
  8. The rise of Mendelian randomization for exploring disease causality: A bibliometric analysis based on CiteSpace.
  9. A bibliometric analysis of surgical treatment for rectal prolapse.
  10. Global research trends on the interaction between gut microbiome and bile acids: a bibliometric and visualized analysis.
  11. Publications by Indian authors on erector spinae plane block: A bibliometric analysis.
  12. How has global research on neural degeneration in glaucoma evolved from 1977 to 2025? A pioneering bibliometric insight into trends, impact, and future directions.
  13. Country-specific citation disparities in Naunyn-Schmiedeberg's Archives of Pharmacology from 2001 to 2024.
  14. Bibliometric Analysis of Septoplasty: Trends, Influential Studies, and Global Contributions.
  15. Acromioclavicular Joint Injury: A Bibliometric Analysis of the 50 Most Cited Articles.
  16. Hotspots and trends of perianal fistula of Crohn's disease: A bibliometric analysis.
  17. Bibliometric Analysis of Exosome Research in Spinal Cord Injury (2000-May 2024). Trends, Collaborations, and Emerging Insights.
  18. Application of artificial intelligence in echocardiography from 2009 to 2024: a bibliometric analysis.
  19. Research hotspots and trends in pediatric telemedicine: a CiteSpace-based bibliometric analysis (1978-2025).
  20. Leveling Up Surgical Skills: A Bibliometric Evaluation of Video Games in Surgical Training Research.
  21. Global research on Chinese martial arts (1974-2025): A bibliometric and visualization-based analysis using Web of Science.
  22. Trends in Dental Education: A Bibliometric Analysis From 2014 to 2023.
  23. Vaginal bacteria and cervical cancer: a bibliometric analysis of trends and themes.
  24. Insight into the research frontier of hypoxia in skin health and diseases: a bibliometric analysis.
  25. Research Trends in Immunomodulatory Therapy for Postmenopausal Osteoporosis: A Bibliometric Analysis.
  26. Bibliometric Analysis of Research Trends Related to the Publication of Clinical Trials on the Treatment of Temporomandibular Disorders Between 1973 and 2023.
  27. Ranking of top 50 optometry academics in African universities by research impact.
  28. Global Trends of teaching methodologies in Oral and Maxillofacial Surgery Education:A 30-Year Bibliometric Analysis.
  29. Global research trends in AI-related foot and ankle surgery research: A bibliometric and visualized study.
  30. Exploring the relationship between intestinal immunity and obesity: A bibliometric and knowledge-map analysis.
  31. Research progress and trends of insect high-temperature stress: insights from bibliometric analysis.
  32. Mapping the future: bibliometric analysis of omics research trends in non-small cell lung cancer.
  33. Neutrophil extracellular traps in cardiovascular disease: a bibliometric analysis (2005-2024).
  34. Current Research Trends and Hotspots in Radiotherapy Combined with Nanomaterials for Cancer Treatment: A Bibliometric and Visualization Analysis.
  35. Correction: Narcolepsy: a machine learning bibliometric analysis (1996-2024).
  36. Bibliometric analysis of research hotspots and emerging trends in mitophagy and atherosclerosis (2004-2024).
  37. Percutaneous versus surgical tracheostomy in mechanically ventilated ICU patients: a bibliometric review and visual analysis (1990-2024).
  38. Bibliometric Insights into Human Metapneumovirus Interventions: Trends, Gaps, and Future Directions.
  39. Global status and research trends of combined heart and lung transplantation: a bibliometrics analysis.
  40. Bibliometric Mapping of Neovagina Creation Research: Trends, Themes, and Global Collaborations.
  41. Bibliometric and Visual Analysis of Research in Food Insecurity and Malnutrition.
  42. Hydrogel in musculoskeletal diseases: Unraveling trends, research foci, and future trajectories via bibliometric insights (from 2000 to 2025).
  43. Integrating Bibliometrics and Bioinformatics to Map Knowledge Structure, Trends, and Genetic Insights in Polycystic Ovary Syndrome and Tumors (2015-2024).
  44. Paradigm shifts in neonatal hypoxic-ischemic encephalopathy therapeutics: a four-decade bibliometric exploration of emerging therapeutic dimensions (1985-2024).
  45. Global Remote Sensing Research: An Author-Centric Analysis of Contributions and Trends.
  46. Open access vs. subscription: comparing the impact of journals in physical therapy and rehabilitation.
  47. Global research hotspots, trends, and future directions of ivermectin research: an informatics investigation (2020-2025).
  48. Salivary biomarkers in diabetes mellitus diagnostics: A bibliometric analysis.
  49. Analysis and Mapping of Machine Learning in the Context of Diabetes.
  50. An overview of the integration and development trends between arts and psychotherapy.
  51. Machine learning based insights into cardiomyopathy and heart failure research: a bibliometric analysis from 2005 to 2024.
  52. Global Insights Into Antipsychotic Research: Bridging Trends and Gaps in Schizophrenia Care (2000-2024).
  53. Global research hotspots and trends of the vaccines: Based on ESI hot papers.
  54. Knowledge mapping of ferroptosis in sarcoma: a bibliometric and bioinformatics analysis (2012-2023).
  55. A Critical Correlate of QS Subject Ranking and Stanford's Top 2% Scientists in Top Dental Schools.
  56. Silent voices: Uncovering women's absence in veterinary surgery publications.
  57. Gender Differences in Publications, Authorship, and Match Patterns Among Neurosurgical Residency Applicants.
  58. Global gender representation in neurointerventional surgery: a natural language processing analysis of journal publications.
  59. Publication Rates of Abstracts Presented at the Urological Society of Australia and New Zealand Annual Scientific Meeting Keith Kirkland and Villis Marshall Session: A Decade-Long Review.
  60. A systematic review of the life cycle cost estimation of upgrading buildings for sustainability.
  61. Precision oncology for NSCLC: a bibliometric exploration of emerging trends and research priorities.
  62. Impact of incorrect affiliations on the recognition of Mexican scientific institutions.
  63. Do organisms need an impact factor? Citations of key biological resources including model organisms reveal usage patterns and impact.
  64. Authorship equity in The Canadian Journal of Emergency Medicine: an analysis of articles between 2000 and 2019.
  65. The scientometric approach to Code Biology: What the title tells about the field.
  1. Cureus. 2025 Jul;17(7): e87688
    A Bibliometric Analysis on Research Trends in Paediatric Epilepsy Treatment From 2005 to 2025.
    Oliver Squires.
      The objective of this bibliometric analysis was to evaluate trends in paediatric epilepsy treatment research from 2005 to 2025. Through assessing which journals, countries, authors, and institutions have been the most productive and mapping trends in keywords used over time, the study aims to reveal emerging areas of interest and inspire ideas for future research. A total of 1418 relevant documents were retrieved from the Web of Science database. Documents outside of the target time period and non-English documents were excluded. From the 1152 remaining documents, 17 duplicates were removed using OpenRefine (OpenRefine). The final 1135 documents were then analysed using VosViewer (VOSviewer - Visualizing scientific landscapes) and Bibliometrix (https://www.bibliometrix.org/). The analysis revealed a stable number of annual global publications until a notable increase since 2018. The USA leads the way with the greatest research output (298 articles) and the highest number of total citations (6565). Harvard University emerged as the most productive institution (111 articles), whilst Epilepsia was the most productive journal (253 articles). Keyword co-occurrence analysis revealed a shift in research from earlier documents focusing more on traditional drug therapies to more recent articles focusing on cannabidiol based therapies, laser ablation, and vagal nerve stimulation. This bibliometric analysis provides new insights into the evolution of paediatric epilepsy treatment research. It helps to demonstrate the leading contributors in the field over the last 20 years, as well as highlighting emerging new trends. The results of the analysis underline the shift in the research away from more traditional treatments to investigating alternative therapies, including cannabidiol based therapies, dietary interventions, laser ablation, and vagal nerve stimulation. Through identifying these trends in the research and mapping author collaboration networks, it is hoped that this study can provide a foundational reference for researchers when planning future studies.
    Keywords:  anti-epileptic; childhood; intervention; management; seizure; therapy
    DOI:  https://doi.org/10.7759/cureus.87688
  2. Cureus. 2025 Jul;17(7): e87659
    Achilles Tendon Rupture: A Bibliometric Study.
    Jacob Markel, Jacob T Williamson, Jordan Pamplin, Victor Anciano.
      Achilles tendon rupture is a frequently addressed subject in foot and ankle research. A bibliometric analysis of the existing literature may provide valuable insights for surgeons and others involved in the diagnosis, treatment, and research of Achilles tendon ruptures. The purpose of this study was to identify and analyze the most-cited research articles regarding Achilles tendon rupture. Using the Web of Science Database, over 1500 publications were identified. The search was refined to include only original articles, resulting in the inclusion of 1,341 articles. Co-authorship between authors was analyzed using a readily available online citation manager software. The 50 most-cited articles were exported into Microsoft Excel for analysis of publication year, journal, authors, and institution of publication. Of the 1,341 articles published between 1948 and 2023, a notable concentration appeared in 2021 and 2022, with 117 and 113 publications, respectively. The 50 most-cited articles were published between 1974 and 2017, and were cited an average of 166 times, ranging from 79 to 672 citations. The American Journal of Sports Medicine was the most prolific journal with 10 of the top 50 most-cited articles. The substantial volume of research on Achilles tendon rupture can make it challenging for surgeons and other stakeholders to navigate the relevant literature. Bibliometric analyses such as this provide a structured overview and help identify the most significant contributions in the field.
    Keywords:  achilles tendon; achilles tendon rupture; bibliometric analysis; research trends; tendon rupture
    DOI:  https://doi.org/10.7759/cureus.87659
  3. J Robot Surg. 2025 Aug 11. 19(1): 475
    The Journal of Robotic Surgery at a glance: productivity, impact, and thematic evolution.
    Siddig Ibrahim Abdelwahab, Manal Mohamed Elhassan Taha, Abdullah Farasani, Jobran M Moshi, Abrar Fahad Alshahrani, Ahmad Assiri, Saeed Alshahrani, Muhammad H Sultan, Khaled A Sahli, Hussam M Shubaily, Omer Ahmed Elrhima, Waseem Hassan.
      This study presents a comprehensive bibliometric evaluation of the Journal of Robotic Surgery (JORS), analyzing its scientific output, thematic evolution, collaboration patterns, and citation performance to support its continued strategic growth in the field of surgical innovation. A total of 2190 articles and reviews published in JORS were retrieved from Scopus (as of July 2025), with 1846 documents receiving 19,031 citations and yielding an h-index of 45. Author productivity analysis revealed ten key contributors with at least 15 publications, led by Patel, V. (26 articles). Their performance was further assessed using advanced bibliometric indicators, including h-index, g-index, m-index, HG Composite, and Q2 Index. Institutional contributions were dominated by North Sichuan Medical College (48 publications), while the United States emerged as the leading national contributor (974 publications), followed by China, the United Kingdom, and Italy. A clear global expansion was noted over time, with the number of contributing countries increasing from 21 in 2007-2010 to 77 by 2021-2025, reflecting growing international collaboration. Thematic mapping using uni-, bi-, and tri-gram keyword analysis highlighted dominant research areas and evolving interests. Citation performance was complemented with SJR and Web of Science metrics, indicating a marked rise in journal impact: Cites per Document increased from 0.769 (2008) to 2.941 (2024), the SJR score rose to 0.764, and the journal impact factor reached 3.0 in 2024. JORS also advanced in journal quartiles, attaining Q1 in Surgery and Q2 in Health Informatics. These findings underscore JORS's growing academic influence and its role as a global platform for advancing robotic surgical science. The hard work of all authors, reviewers, editorial board and honorable editor-in-chief is sincerely appreciated.
    Keywords:  Bibliometric analysis; Citation performance; Journal Impact Factor; Journal of Robotic Surgery; Keyword analysis; Top contributors
    DOI:  https://doi.org/10.1007/s11701-025-02652-3
  4. Front Microbiol. 2025 ;16 1630924
    Trends and hotspots in global influenza and intestinal flora research based on bibliometrics.
    Dongsheng Wu, Tongtong Wang, Haoran Wu, Yuang Dong, Ziqin Huang, Jun Zhang, Wei Zhang.
       Objective: Influenza (hereinafter referred to as influenza) is a pandemic and seasonal respiratory infectious disease that can lead to a global pandemic, posing a major threat to global public health. Studies have shown that influenza can lead to an imbalance in the intestinal flora, and disruption of the intestinal flora can exacerbate the progression of the disease, suggesting a potential link between influenza and intestinal flora. There is still a lack of systematic summary of bibliometric analysis in this field, therefore, this study aims to reveal the research dynamics, collaborative networks and cutting-edge hotspots in the field of influenza-intestinal flora association through bibliometric methods.
    Methods: Bibliometric analysis was used to retrieve 554 papers on influenza and intestinal flora from the Web of Science Core Collection (WoSCC) database from 2011 to 2025. After screening, 283 papers were included, and co-occurrence and clustering analyses of countries, authors, institutions, journals, references, and keywords were performed using VOSviewer, CiteSpace, and Bibliometrix; statistical visualization was performed via Microsoft Excel.
    Results: China is the country with the highest number of published papers and the leading CSI in terms of international collaboration intensity. The most popular journal in this field is Frontiers in Microbiology with 20 publications, while the most influential journal is Nature with 605 citations. Zhejiang University was the institution with the highest number of publications and Francois Trottein was the most prolific author. Keyword co-occurrence analysis showed that gut microbiota, influenza, probiotics, intestinal microbiota and COVID-19 were the core research hotspots, and clustering analysis further revealed the "intestinal-pulmonary axis of immunoregulation," such as Cluster analysis further revealed the "intestinal-lung axis immunoregulation," such as Th17/Treg balance, short-chain fatty acids and probiotics, as the cutting edge.
    Conclusion: This study is the first to systematically map the bibliometrics of influenza and gut flora. The most influential countries, research institutions and researchers were identified through bibliometric analysis, showing the current research trends and hotspots in influenza and intestinal flora control. The results can provide theoretical guidance for future influenza prevention and control strategies targeting flora.
    Keywords:  bibliometric analysis; influenza; intestinal flora; intestinal-lung axis immunomodulation; research trends
    DOI:  https://doi.org/10.3389/fmicb.2025.1630924
  5. Medicine (Baltimore). 2025 Aug 08. 104(32): e43684
    Bibliometric and visual analysis of quercetin in kidney disease from 2000 to 2022.
    Xingzheng Liu, Xuerui Yang, Jinying Mo, Yufei Song, Ling Peng, Gaofeng Song.
       BACKGROUND: Due to the complexity and challenges in the treatment of kidney diseases, it is particularly important to explore new therapeutic approaches, such as natural plant components, to enhance efficacy and reduce toxic side effects. In recent years, quercetin has received widespread attention from researchers in the field of kidney diseases, and a series of clinical and animal experiments have been conducted, resulting in a large number of academic papers and publications. This study conducts a bibliometric analysis to understand the current research status, research hotspots, and development trends of quercetin in kidney diseases, aiming to provide potential research directions for further studies on the treatment of kidney diseases.
    METHODS: Publications were retrieved related to quercetin and the kidney from the Science Citation Index Expanded database within the Web of Science Core Collection. Bibliometric analysis was performed, including annual publication analysis, keyword co-occurrence analysis, collaboration network analysis, and citation analysis, using software such as VOSviewer, CiteSpace, Bibliometrix package based on R software, and Microsoft Excel. The results of the bibliometric analysis were visualized.
    RESULTS: This study included a total of 1253 literature items related to quercetin and kidney diseases between the years 2000 and 2022. The annual publication output showed an overall exponential growth trend. The most frequent keywords were "quercetin" followed by "oxidative stress." J Ethnopharmacol was the journal with the highest publication output in this field. Yin Xiaoxing was the most prolific author, and King Saud University was the institution with the highest publication count. As for countries, China had the highest publication count.
    CONCLUSION: Through bibliometrics analysis, it has been found that quercetin has received increasing attention from researchers in the field of kidney diseases. The oxidative stress and antioxidant properties of quercetin are the main areas of focus. Diabetic nephropathy is the primary disease being studied. Network pharmacology is an emerging research method, with a particular emphasis on studying the relevant signaling pathways.
    Keywords:  bibliometric; kidney disease; quercetin; web of science
    DOI:  https://doi.org/10.1097/MD.0000000000043684
  6. Medicine (Baltimore). 2025 Aug 08. 104(32): e43749
    Visualized analysis of trends and hotspots in global refeeding syndrome: A bibliometric analysis study (2000-2024).
    Xue Zhan, Hao Wang.
       OBJECTIVE: Refeeding syndrome (RFS) is a serious metabolic condition that arises when nutritional support is reintroduced to malnourished patients, particularly after prolonged starvation. This study conducts a bibliometric analysis of RFS research, mapping global trends, key contributors, and collaborative networks.
    METHODS: A comprehensive literature search was performed using the Web of Science Core Collection database, with publications spanning from 2000 to 2024. We analyzed data using VOSviewer, CiteSpace, and the R package "bibliometrix," focusing on publication volume, citations, collaborations, and keyword trends.
    RESULTS: The analysis included 530 publications, with the USA leading in research output, followed by the UK and Australia. Top institutions included the University of London, University of California System, and University of Bern. Key journals contributing to the field were Nutrition in Clinical Practice, Clinical Nutrition, and Nutrients. Notable authors were Zeno Stanga, Philipp Schuetz, and Arthur R.H. van Zanten. Core keywords included "multicenter," "critically ill patients," and "prevention" with recent bursts in keywords such as "prevention," "outcome," and "medical inpatients."
    CONCLUSIONS AND IMPLICATIONS: This bibliometric study provided a comprehensive overview of the evolving research landscape concerning RFS. Key priorities included identifying at-risk populations, optimizing nutritional interventions, and standardizing management to address metabolic challenges.
    Keywords:  CiteSpace; VOSviewer; bibliometric analysis; hypophosphatemia; refeeding syndrome
    DOI:  https://doi.org/10.1097/MD.0000000000043749
  7. Medicine (Baltimore). 2025 Aug 08. 104(32): e43795
    The evolution of the impact of educational background on oral health: A bibliometric and visualized analysis from 2000 to 2024.
    Linxin Jiang, Bincheng Liu, Simin Li, Shaohong Huang, Daniel R Reissmann, Gerhard Schmalz, Xianda Hu.
       BACKGROUND: Educational background is a major associated factor on oral health. However, comprehensive analyses of global research trends in this field remain limited. This study aimed to analyze the current status, hotspots, and developmental trends in research on the impact of educational background on oral health.
    METHODS: This study conducted a comprehensive bibliometric analysis using data from the Web of Science Core Collection database, covering the period between 2000 and 2024. The search strategy combined terms related to education and oral health. A total of 1080 articles were retrieved and analyzed using GraphPad 8.0.2, CiteSpace 6.2. R6, and VOSviewer 1.6.20 visualization software. This study examined publication trends, countries/regions, journals, institutions, authors and research hotspots.
    RESULTS: The analysis revealed a steady increase in publications over the study period, with a notable surge in the past 4 years. The United States of America, the United Kingdom, Australia, China, and Brazil emerged as the leading countries. With the exception of 1 institution and 1 author from Brazil, the top 5 institutions, authors, and journals in terms of publication, citation, and collaboration strength are all from developed countries. Keyword co-occurrence analysis revealed that the predominant research keywords are centered most around health literacy. Keywords clustering grouped the terms into twelve categories, and the cluster of oral health education is the most highly focused area. The analysis of keyword temporal trends reveals a gradual decline in prominent research clusters over time, from 7 to 5 and then to 4. From 2020 to 2024, oral health knowledge, older adults, diseases, and students are emerging hotspots.
    CONCLUSION: The research landscape on the impact of education on oral health is dynamic and holds significant potential for further development. Enhanced collaboration among countries, institutions, and authors is essential to foster interdisciplinary advancements and address global challenges within this field. Recent trends in research indicate a growing specialization within subdomains and an increasing emphasis on early prevention.
    Keywords:  bibliometric analysis; education; oral health; oral health disparities; socio-economic factors
    DOI:  https://doi.org/10.1097/MD.0000000000043795
  8. Medicine (Baltimore). 2025 Aug 08. 104(32): e43764
    The rise of Mendelian randomization for exploring disease causality: A bibliometric analysis based on CiteSpace.
    Kunyang He, Xiaochu Wu, Zhengyu Qian, Kaijie Lin, Yue Wang, Zhikun Su, Tianyao Zhang.
       OBJECTIVE: Mendelian randomization (MR) utilizes genetic variants as instrumental variables to explore causal associations between exposures and outcomes. Despite a significant increase in MR-related publication volume in recent years, accompanying bibliometric analyses are lacking. Hence, our study aims to conduct a bibliometric analysis of MR articles published within the last 20 years to elucidate the current research landscape and identify potential future directions.
    METHODS: We searched the Web of Science Core Collection for articles related to MR from 2003 to 2023. The analysis utilized CiteSpace 6.1.R6 and Excel to examine annual publication volume, keywords, journals, countries, institutions, authors, co-cited references, and highly cited articles.
    RESULTS: A total of 7801 articles in the MR field were retrieved between 2003 and 2023, demonstrating a rapid growth in annual publication volume. "INT J EPIDEMIOL" not only possesses the largest academic output but also boasts the highest co-citation. England contributed the largest number of papers, and the Univ Bristol topped the list with the most articles. George Davey Smith is the most prolific author. The article from Hemani G et al (2018) had the most co-citations. England, the Univ Bristol, and Smith, GD played pivotal roles in highly cited articles. Research hotspots primarily encompassed cardiovascular diseases, metabolic diseases, biomarkers, inflammation, Alzheimer disease, cancer, age. Emerging research frontiers in the last 3 years featured obstructive sleep apnea, psychiatric disorders, major depressive disorder, and coffee consumption.
    CONCLUSIONS: This study has reviewed the research status and trends in the MR field from 2003 to 2023. These findings provide invaluable insights and guidance for the future development of the MR field.
    Keywords:  CiteSpace; Mendelian randomization research; differential analysis; highly cited papers analysis; visualization
    DOI:  https://doi.org/10.1097/MD.0000000000043764
  9. Medicine (Baltimore). 2025 Aug 08. 104(32): e43763
    A bibliometric analysis of surgical treatment for rectal prolapse.
    Li Feng, Min Wang, Xin Li, Qifeng Yang.
       BACKGROUND: Rectal prolapse is a serious disease characterized by the protrusion of rectal tissue through the anal orifice, predominantly affecting elderly women and significantly impairing quality of life. Surgical intervention remains the definitive treatment, yet debates persist regarding optimal techniques, recurrence rates, and functional outcomes. Despite advancements in minimally invasive approaches, a systematic synthesis of global research trends, collaborative networks, and thematic evolution in this field remains unexplored.
    OBJECTIVES: This study aimed to conduct the first bibliometric analysis of surgical treatments for rectal prolapse, mapping global research trends, collaborative networks, and thematic evolution. Key objectives included identifying leading contributors (countries, institutions, and authors), analyzing shifts in surgical techniques, and highlighting gaps in international collaboration and technological integration to guide future research priorities.
    METHODS: A bibliometric analysis was performed using 999 English-language publications from the Web of Science Core Collection (2000-2024). Data were analyzed for annual publication trends, geographic and institutional productivity, citation impact, and co-authorship networks. Keyword clustering and burst detection identified emerging themes and technological shifts, while centrality metrics assessed the influence of countries and institutions.
    RESULTS: (1) Publication trends: Annual output grew from 24 (2000) to 61 (2024), stabilizing post-2010, suggesting technological maturation. (2) Geographic contributions: The United States dominated with 236 articles (5296 citations) and high centrality. China and Japan produced moderately but exhibited limited global collaboration. (3) Institutional networks: Cleveland Clinic institutions led collaborative networks, while authors like Lindsey and Cunningham drove high-impact research. (4) Thematic clusters: Five themes emerged: surgical strategies (e.g., "ventral mesh rectopexy"), pelvic floor dysfunction, risk mitigation, complication management, and symptom associations. A shift toward minimally invasive techniques was evident. (5) Research gaps: Disparities in international collaboration, institutional influence, and integration of emerging technologies (AI/virtual reality) were identified. Priorities include establishing standardized registries, fostering inclusive consortia, and addressing ethical concerns for novel surgical materials.
    CONCLUSION: This study underscores 3 pivotal imperatives for advancing rectal prolapse surgery research: global registries, inclusive consortia, and tech adoption to enhance outcomes.
    Keywords:  bibliometric analysis; international collaboration; minimally invasive surgery; rectal prolapse; research trends; surgical treatment; ventral mesh rectopexy
    DOI:  https://doi.org/10.1097/MD.0000000000043763
  10. Front Cell Infect Microbiol. 2025 ;15 1616995
    Global research trends on the interaction between gut microbiome and bile acids: a bibliometric and visualized analysis.
    Fangli Luo, Luqiang Sun, Renhong Wan, Zhen Tian, Zhaoxuan He.
       Background: An increasing number of studies have shown that gut microbiome-bile acids interactions play a crucial role in host health and disease. This bibliometric analysis aims to identify the global scientific output, research hotspots, and frontiers of gut microbiome-bile acids in the past two decades.
    Methods: We searched the relevant studies of gut microbiome-bile acids published between 2004 and 2024 in the Web of Science Core Collection database. Microsoft Excel 2019, VOSviewer 1.6.18, Tableau Desktop 2024.2.2, Scimago Graphica 1.0.45, and CiteSpace 6.2.R3 were used to analyze the publications, countries/regions, institutions, journals, authors, references, and keywords.
    Results: A total of 4795 original articles and reviews were collected. A visual analysis of the results showed that the number of publications increased rapidly over time. China published the most papers, the United States had the most citations, and the most productive institution was Shanghai Jiaotong University. The most prolific author was Jia Wei, and Jason M. Ridlon was the most frequently co-cited author. Nutrients was the most productive journal. In the keyword co-occurrence network, except for gut microbiome and bile acids, inflammation becomes the keyword with the highest frequency. Keywords and reference analysis show that metabolic diseases (such as obesity and type 2 diabetes mellitus), cancer (such as colorectal cancer), and disease-related mechanisms (such as tgr5 and pathway) are the hot topics and future research trends in this field.
    Conclusion: In this study, bibliometric analysis was utilized to explore the relationship between gut microbiome and bile acids. The findings can reflect the current hotspots and new directions of gut microbiome-bile acids, and provide an objective description and comprehensive guidance for future related studies.
    Keywords:  Citespace; VOSviewer; bibliometrics; bile acids; gut microbiome; visualization
    DOI:  https://doi.org/10.3389/fcimb.2025.1616995
  11. Indian J Anaesth. 2025 Aug;69(8): 779-785
    Publications by Indian authors on erector spinae plane block: A bibliometric analysis.
    Tuhin Mistry, Abhijit S Nair, Ujjwalraj Dudhedia, Sandeep Diwan.
      The erector spinae plane block (ESPB), first described in 2016, has gained immense popularity worldwide due to its simplicity and effectiveness in providing pain relief for various surgeries. This bibliometric analysis aims to assess the contribution of Indian authors to the body of literature on ESPB. We searched Scopus using the keywords 'erector spinae plane block' and 'India'. The retrieved data were analysed using VOSviewer software. The analysis was done for co-authorship, co-occurrence, citation, bibliographic coupling and co-citation. From the 485 hits obtained after the database search, we included 262 articles for bibliometric analysis using the VOSviewer software. Co-authorship networks were identified among the All India Institute of Medical Sciences (AIIMS) in Bhubaneswar, the Postgraduate Institute of Medical Education and Research in Chandigarh and Sree Balaji Medical College in Chennai. The majority of publications originated from AIIMS, New Delhi and Bhubaneshwar. The Indian Journal of Anaesthesia published the highest number of ESPB-related articles (50), which collectively received 527 citations. This bibliometric analysis provides comprehensive details of the journals, citations, authors and institutions that have published articles on ESPB, including those authored by researchers from India. The findings may guide future research planning and collaboration using ESPB as an intervention.
    Keywords:  Anaesthesia; India; analgesia; authorship; bibliometric analysis; citation; erector spinae plane block; regional anaesthesia; research
    DOI:  https://doi.org/10.4103/ija.ija_244_25
  12. Int Ophthalmol. 2025 Aug 13. 45(1): 335
    How has global research on neural degeneration in glaucoma evolved from 1977 to 2025? A pioneering bibliometric insight into trends, impact, and future directions.
    Kai-Yang Chen, Hoi-Chun Chan, Chi-Ming Chan.
      Neural degeneration plays a central role in the pathogenesis of glaucoma, contributing to vision loss and disease progression. To identify research gaps and emerging trends, a focused bibliometric analysis of this domain was conducted. This study analyzed global research trends on neural degeneration in glaucoma from 1977 to 2025 using the Web of Science Core Collection (WoSCC), with the search completed on 1 June 2025. The systematic search targeted terms related to nerve degeneration, neuroprotection, glaucomatous axonopathy, optic nerve, and retinal ganglion cells. A total of 3680 relevant documents were retrieved and analyzed using R-bibliometrix, Biblioshiny, and VOSviewer software. Analysis included publication trends, key journals, prolific authors, citation patterns, and collaboration networks. Scientific output increased significantly from the 1990s, peaking with over 200 articles annually by 2019, followed by a moderate decline post-2020. Top journals included Investigative Ophthalmology & Visual Science (314 articles) and Experimental Eye Research (161 articles). Bradford's Law identified a set of core sources contributing the majority of publications. Influential authors included Weinreb RN and Quigley HA, each with over 70 publications. The USA and China led in publication volume, while the USA dominated in citations with approximately 50,918. Co-authorship analysis revealed collaborative clusters, emphasizing the interdisciplinary nature of this field. Trending keywords evolved from foundational terms like "retinal ganglion cells" to advanced topics such as "optical coherence tomography angiography" and "intracellular-pressure." This bibliometric review outlines key patterns in glaucoma neurodegeneration research and highlights opportunities for future scientific inquiry.
    Keywords:  Bibliometric analysis; Citation trends; Collaborative networks; Glaucoma; Neural degeneration; Retinal ganglion cells
    DOI:  https://doi.org/10.1007/s10792-025-03700-5
  13. Naunyn Schmiedebergs Arch Pharmacol. 2025 Aug 14.
    Country-specific citation disparities in Naunyn-Schmiedeberg's Archives of Pharmacology from 2001 to 2024.
    Roland Seifert, Waseem Hassan.
      This bibliometric study examined disparities in research output and citation impact in 4155 (including all types of documents) research documents published in Naunyn-Schmiedeberg's Archives of Pharmacology (NSAP) from 2001 to 2024. The objective was to assess how publication volume and citations vary across countries, i.e., high-income countries (HICs), upper-middle-income and lower-middle-income countries (UMICs and LMICs). Germany led in both number of publications (770 publications) and total citations (17,569), followed by China, India, the United States, and Egypt. Regression-based citation analysis by country group revealed pronounced disparities. In the low-output category (11-51 publications), HICs such as Norway, Switzerland, and Sweden demonstrated citation performance far above expectations, while several LMICs underperformed despite comparable output levels. In the moderate-output group (85-169 publications), citation correlation weakened overall. While the Netherlands and the UK maintained high impact, middle-income countries like South Korea and Saudi Arabia showed limited citation impact. Among high-output countries (240-769 publications), citation performance was more consistent (R2 = 0.731), with Germany, the US and Japan significantly outperforming other contributors. Conversely, UMICs such as China, India, Iran, and Egypt-despite high output-lagged in citation returns, suggesting a gap between quantity and influence. The disparities in citation performance persisted in both original and review categories, underscoring the structural imbalance in global research influence. In conclusion, while NSAP has expanded its international scope and output, substantial citation inequality remains across country income groups. These findings highlight the need for targeted editorial, collaborative, and policy strategies to enhance research visibility and recognition in UMICs and LMICs.
    Keywords:  Bibliometric analysis; Citations; Disparity; NSAP; Publications; Scopus
    DOI:  https://doi.org/10.1007/s00210-025-04499-9
  14. J Craniofac Surg. 2025 Aug 14.
    Bibliometric Analysis of Septoplasty: Trends, Influential Studies, and Global Contributions.
    Soumil Prasad, Rohan Mangal, Seth Thaller.
      Septoplasty is a frequently performed nasal airway procedure, yet the influence and provenance of its scientific literature have not been systematically quantified. We searched Clarivate Web of Science for "septoplasty," retrieved 2,528 records, and ranked them by citations. The 50 most-cited English-language articles were analyzed for citation count, publication year, country, institutional affiliation, authorship frequency, and Oxford Level of Evidence (LOE). Regression tested whether article characteristics predicted citation volume. The 50 papers accumulated 5639 citations (mean ± SD=112.8 ± 57.8; range=68-383). Publication years spanned 1989 to 2018, with a peak of 5 influential papers in 2010 (626 citations). Four authors-Rhee, Most, Garcia, and Kimbell-each authored 4 of the top papers. The United States produced half of all articles (25) and 3158 citations, far exceeding Canada (4 papers, 405 citations) and Germany (4, 389). Institutions with the highest output were the Medical College of Wisconsin (11 papers, 1,468 citations) and the University of North Carolina at Chapel Hill (7, 829). LOE distribution favored retrospective cohort studies (level III: 34/50). Univariate analysis showed no citation association with LOE (P=0.445), article length (P=0.946), or publication year (P=0.666), whereas country of origin was significant (P=0.016); multivariate models confirmed higher citations for United States, Turkish, and Italian studies. These findings demonstrate that septoplasty scholarship is dominated by a small group of authors and US centers, relies largely on Level III evidence, and that geographic origin-not study design-best predicts citation impact. Targeted international collaboration and higher-quality prospective research are needed to diversify and strengthen future septoplasty literature.
    Keywords:  Bibliometric analysis; citation trends; nasal airway surgery; research impact; septoplasty
    DOI:  https://doi.org/10.1097/SCS.0000000000011708
  15. Arch Bone Jt Surg. 2025 ;13(7): 395-405
    Acromioclavicular Joint Injury: A Bibliometric Analysis of the 50 Most Cited Articles.
    Grace L Basralian, Paxton Sweeney, Daniel Calem, Eitan Kohan.
       Objectives: This study aims to identify the 50 most influential articles on acromioclavicular (AC) joint injury, exploring research trends and treatment options.
    Methods: Utilizing the Scopus database, the 50 top-cited articles were selected based on predefined criteria and analyzed for bibliometrics, including authorship, journal, and evidence level.
    Results: From 1963 to 2021, these articles amassed 3,363 citations, primarily comprising case series with level IV evidence, published across 19 journals from eight countries.
    Conclusion: This review highlights the dynamic progression in AC joint injury management and signals the urgent need for advanced research to enhance clinical decision-making and evidence-based practices.
    Keywords:  Acromioclavicular joint; Acromioclavicular joint treatment; Bibliometric analysis; Shoulder
    DOI:  https://doi.org/10.22038/ABJS.2024.81587.3759
  16. Medicine (Baltimore). 2025 Aug 08. 104(32): e43854
    Hotspots and trends of perianal fistula of Crohn's disease: A bibliometric analysis.
    Lei Liang, Lan Li, Dexin Wang, Xiubi Zhang, Xiaohe Zhang, Gang Tian, Chaochi Yue, Weiliang Du.
       BACKGROUND: Perianal fistula is a frequent and severe complication of Crohn disease (CD). With the rising incidence of perianal fistulas in CD (pfCD), research activity in this field has grown substantially. Although several reviews have addressed CD and pfCD, comprehensive analyses summarizing research trends and hotspots in pfCD remain limited.
    METHOD: Relevant articles and reviews were retrieved from the Web of Science Core Collection database. Citespace (version 6.3.1), Scimago Graphica (version 1.0.42), and VOSviewer (version 1.6.15) were used to systematically analyze data on publications, countries, institutions, authors, and keywords.
    RESULTS: Visual analysis of 692 articles on pfCD from 2004 to 2024 revealed evolving trends and research foci in the field. From 2004 to 2015, annual publication output remained relatively stable; however, it increased markedly thereafter, reaching 65 articles in 2024. Institutions from Europe and North America have contributed substantially to the field. Recent studies have focused on mesenchymal stem cells therapy, anti-tumor necrosis factor treatment, surgical interventions, diagnostic strategies, and therapeutic outcomes.
    CONCLUSION: This bibliometric analysis provides a comprehensive overview of developmental trends and emerging hotspots in pfCD research, offering valuable insights for future investigations.
    Keywords:  Crohn disease; bibliometric analysis; perianal fistula; perianal fistula of Crohn disease; therapy
    DOI:  https://doi.org/10.1097/MD.0000000000043854
  17. Drug Des Devel Ther. 2025 ;19 6829-6848
    Bibliometric Analysis of Exosome Research in Spinal Cord Injury (2000-May 2024). Trends, Collaborations, and Emerging Insights.
    Zhihua Wang, Hangchuan Bi, Denghui Li, Wan Zhang, Chao Wang, Jianyi Yang, Xianglin Shen, Rongji Yan, Fei He, Hao Duan.
       Purpose: Exosomes have emerged as promising therapeutic agents for spinal cord injury (SCI). The present study was conducted to provide a systematic bibliometric analysis of research trends related to SCI and exosomes.
    Patients and Methods: Publications on exosomes in SCI were identified from the Web of Science Core Collection using specific search criteria. VOSviewer, CiteSpace, and R-based Bibliometrix were employed to visualize collaboration networks and research hotspots.
    Results: The analysis included 281 publications across 66 countries. The publication numbers were consistently trending upwards, with the United States and China being two of the top producing countries. The top three articles were cited 539, 300, and 254 times, respectively. The analyzed publications were from 153 journals, and the Journal of Neurotrauma, Journal of Nanobiotechnology, and Stem Cell Research & Therapy had the highest total link strength in co-occurrence networks. Stem Cell Research & Therapy, Journal of Nanobiotechnology, and Molecular Neurobiology were the top journals in coupling networks. Fan Jin, Cai Weihua and Cao Yong were the most prolific and highly cited authors. Keywords analysis revealed emerging research hotspots including microglia modulation, engineered exosomes, extracellular vesicles, and targeted delivery systems.
    Conclusion: The findings underscore the accelerated exploitation and promise of exosomes as a novel treatment for SCI with significant translational potential through emerging hotspots such as microglia modulation and engineered exosome platforms. The insights gained from this study are important and may be essential for the advancement of exosome-based treatments by researchers and clinicians in the field of spinal cord injury.
    Keywords:  bibliometrics; exosome; extracellular vesicles; spinal cord injury; targeted delivery systems; therapy
    DOI:  https://doi.org/10.2147/DDDT.S522129
  18. Front Med (Lausanne). 2025 ;12 1587364
    Application of artificial intelligence in echocardiography from 2009 to 2024: a bibliometric analysis.
    Yangli Liu, Lei Zhao, Bin Tu, Jie Wang, Yaqun He, Rufang Jiang, Xiaofeng Wu, Wen Wen, Jian Liu.
       Background: Echocardiography is a cornerstone in the clinical diagnosis of cardiovascular diseases, providing critical insights into cardiac structure and function. Over recent years, artificial intelligence (AI) has emerged as a transformative adjunct to traditional echocardiographic techniques, enhancing diagnostic accuracy through innovations such as automatic view labeling, advanced image segmentation, and predictive disease modeling. The objective of this study is to explore the current status and prevailing research trends in this field from 2009 to 2024 through bibliometric analysis and to forecast future developmental trajectories.
    Methods: We selected the Science Citation Index Expanded (SCI-Expanded) from the Web of Science Core Collection (WOSCC) as our primary data source and conducted a comprehensive search encompassing all articles and reviews published between 2009 and 2024 and used the online analysis platform of bibliometrics, CiteSpace and VOSviewer software to analyze countries/regions, institutions, authors, keywords, and references, used Microsoft Excel 2021 to visualize the trends of the number of articles published by year.
    Results: Between 2009 and 2024, a total of 3,411 publications on AI applications in echocardiography were identified, including 3,000 articles (87.9%) and 411 reviews (12.1%), contributed by researchers from 100 countries/regions. China and the USA were the leading contributors in terms of publication volume. Notably, institutions such as Shanghai Jiaotong University demonstrated strong research productivity and international collaboration. Journal of the American College of Cardiology ranked among the most influential journals in this domain. Keyword analysis revealed that terms such as "artificial intelligence," "machine learning," "deep learning," and "echocardiography" are central research hotspots, indicating emerging trends in the field and the potential to evolve into major areas of future investigation.
    Conclusion: Over the past decade, the integration of AI with echocardiography has become increasingly sophisticated. This study highlights the critical contributions of AI applications in echocardiography to the progression of the field and offers valuable insights for researchers embarking on future investigations.
    Keywords:  artificial intelligence; bibliometric analysis; echocardiography; hot spots; visualization
    DOI:  https://doi.org/10.3389/fmed.2025.1587364
  19. Front Pediatr. 2025 ;13 1590663
    Research hotspots and trends in pediatric telemedicine: a CiteSpace-based bibliometric analysis (1978-2025).
    Hong Xie, Dan Luo, Bingyao Kang.
       Aim: Given the rapid growth yet fragmented nature of pediatric telemedicine research, this study employed bibliometric analysis to address specific research questions regarding key publications, leading authors, core journals, prominent institutions, thematic structures, and research theme evolution. The findings were aimed at providing an objective, panoramic view to guide future research priorities and clinical practice development in pediatric telemedicine.
    Methods: A retrospective bibliometric analysis was conducted on publications in the field of telemedicine in pediatrics, covering the time period from 1978 to 2025. The data were downloaded from the Web of Science Core Collection on March 4, 2025. This study analyzed the annual number of publications and citations, explored relationships between authors, institutions, countries, and keywords, and identified emerging trends and research frontiers in the field of telemedicine in pediatrics.
    Results: A total of 114 countries and 120 institutions published articles on pediatric telemedicine. Co-occurring keywords and cluster analysis indicate that recent major research trends in the field of pediatric telemedicine include telepsychiatry for mental health, autism spectrum disorders, and parent training, as well as digital health for care, service, and quality of life. Additionally, tele-diagnosis and care of, obesity, retinopathy of prematurity, critical care, and traumatic brain injury are also popular research areas.
    Conclusion: The United States has a significant presence in the field of pediatric telemedicine. Although telemedicine is growing rapidly in pediatrics, it cannot replace face-to-face care.
    Keywords:  bibliometric analysis; citespace; data visualization; pediatric; telemedicine
    DOI:  https://doi.org/10.3389/fped.2025.1590663
  20. J Craniofac Surg. 2025 Aug 14.
    Leveling Up Surgical Skills: A Bibliometric Evaluation of Video Games in Surgical Training Research.
    Soumil Prasad, Mason Thornton, Levi Travis, Adam Osman, Mason Flanagan, Seth Thaller.
      To map publication trends and research themes on video games in surgical training through bibliometric techniques. Retrospective, descriptive bibliometric analysis of records indexed in the Web of Science Core Collection. Metrics included yearly publication counts, citation impact, leading authors and institutions, journal outlets, country of origin, study design, and keyword co-occurrence. A comprehensive search retrieved 464 records. After relevance screening, the fifty most-cited works (articles, conference papers, reviews) were analyzed. Annual output rose sharply after 2011, with peaks in 2016 and 2020-2021; 30 of the 50 high-impact papers were published within the past decade. Citation counts were highly skewed: the landmark study by Rosser (2007) amassed 423 citations, one quarter of the total. James C. Rosser Jr. and Maarten B. Jalink were the most prolific authors, while Beth Israel Medical Center and the University of Groningen led institutional contributions. Journal of Surgical Education and Surgical Endoscopy each published 5 of the core papers. Authors based in the United States produced 30% of studies, followed by the Netherlands, the United Kingdom, and Germany. Observational designs predominated (70%), with experimental work (15%) and reviews (12%) forming smaller but growing segments. Keyword mapping revealed 4 principal clusters: laparoscopic skills acquisition, simulation-based education, preoperative warm-up exercises, and robotic surgery training. Research on video game-mediated surgical education is expanding, international, and increasingly diversified in methodology and focus, yet remains dominated by a small group of authors and institutions.
    Keywords:  Bibliometrics; laparoscopic skills; simulation; surgical training; video games
    DOI:  https://doi.org/10.1097/SCS.0000000000011686
  21. Medicine (Baltimore). 2025 Aug 08. 104(32): e43769
    Global research on Chinese martial arts (1974-2025): A bibliometric and visualization-based analysis using Web of Science.
    Wei Chen, Syahrul Ridhwan Morazuki.
       BACKGROUND: Chinese martial arts (Wushu), representing both competitive sports and cultural heritage, have gained global recognition for their health-promoting benefits. However, a systematic scientometric overview of global Wushu research is still lacking.
    OBJECTIVE: This study systematically examines global research trends, thematic hotspots, collaboration networks, and scientific impacts of Chinese martial arts from 1974 to 2025.Materials and Methods: This study systematically retrieved English-language articles and reviews from the Web of Science Core Collection (SCI-Expanded and SSCI) published between January 1974 and March 2025, using topic-related terms such as "Wushu," "Chinese Martial Arts," "Kung Fu," "Taijiquan," and "Tai Chi." A total of 3955 records were included. The search strategy was refined through multiple rounds of preliminary retrieval and keyword calibration to ensure data accuracy and reproducibility. Bibliometric and scientometric analyses were conducted using Bibliometrix (R version 4.4.3) and its Biblioshiny interface, VOSviewer (version 1.6.20), and CiteSpace (version 6.2.6). The analysis covered publication trends, keyword co-occurrence, collaboration networks, thematic evolution, and citation structures. In addition, linear regression modeling was employed to assess the goodness of fit for annual publication trends.
    RESULTS: Global Wushu research has expanded significantly since the 2000s, with an annual growth rate of 9.41% and a peak of 373 articles in 2022. Research prominently focuses on Tai Chi for balance enhancement, fall prevention, chronic disease management, and mental health, especially in older adults. Keywords such as "Tai Chi," "exercise," and "older adults" dominate. China (41.9%) and the United States (24.4%) lead in publications; however, China's international collaboration (20.6%) is lower compared to the US, Australia, and the UK. Institutionally, Harvard University and Chinese sports and medical universities dominate, while Hong Kong institutions bridge East-West collaborations. High-impact journals like Cochrane Database emphasize clinical applications. Although Chinese scholars lead in productivity, American authors achieve higher citations.
    CONCLUSION: Over 5 decades, Wushu research has transitioned from traditional techniques to multidisciplinary health sciences, integrating geriatric care, cognitive interventions, and chronic disease rehabilitation. Strengthening international collaboration, exploring underlying mechanisms, and developing personalized digital interventions represent key future directions to enhance the global scientific impact of Chinese martial arts.
    Keywords:  Chinese martial arts; Tai Chi; bibliometric analysis; international collaboration; scientific development
    DOI:  https://doi.org/10.1097/MD.0000000000043769
  22. J Dent Educ. 2025 Aug 12.
    Trends in Dental Education: A Bibliometric Analysis From 2014 to 2023.
    Jili Chen, Qing Wang, Wanwei Shi, Lina Bao, Jingxin Weng, Yao Lin, Zeng Fan.
       OBJECTIVES: Bibliometrics helps to reveal the internal relations and development trends of the subject field. This study employs bibliometric analysis to provide a comprehensive scope of dental education over the past decade.
    METHODS: The Web of Science core collection was searched for articles about dental education between January 1, 2014, and December 31, 2023. The CiteSpace and SCImago Graphica software were used to extract and visualize the data, which included information about the number of publications, countries, institutions, authors, keywords, and other details.
    RESULTS: 2472 research articles and reviews were included, and the yearly publishing volume demonstrated a general increasing trend over the previous ten years. The United States was a significant nation in the national cooperation network and had the most publications overall (1257 articles). Around 463 writers were included, and M. R. Inglehart was the scholar with the most publications. The most frequent keyword is "dental education". The keywords burst analysis revealed that mental health, online learning, and virtual reality might be the key areas of focus in future research.
    CONCLUSION: This study identified key trends in dental education, emphasizing the need for curriculum optimization and digital innovation. Educators should integrate digital technologies and psychological concepts to improve teaching methods and adapt to evolving educational needs in the future.
    Keywords:  bibliometric analysis; dental education; dental student
    DOI:  https://doi.org/10.1002/jdd.70009
  23. Front Microbiol. 2025 ;16 1615944
    Vaginal bacteria and cervical cancer: a bibliometric analysis of trends and themes.
    Xiaoxia Liu, Yinghui Zhao, Xianhua Meng, Zheng Gao, Xiaohong Wang, Fengyong Yang.
       Background: Cervical cancer remains a significant global health challenge, with increasing evidence suggesting the crucial role of vaginal bacteria in its development and progression. This study aims to analyze the global research landscape and trends in vaginal bacteria and cervical cancer research through bibliometric analysis.
    Methods: Literature data were retrieved from the Web of Science Core Collection (WOSCC) database. Bibliometric analysis was performed using VOSviewer, CiteSpace, and R-bibliometrix to evaluate publication patterns, research collaboration networks, and emerging trends.
    Results: A total of 372 publications were identified, showing an annual growth rate of 8.41%. China and USA emerged as leading contributors, with the Imperial College London and University of Arizona being the most productive institutions. Herbst-Kralovetz MM and Laniewski P were identified as the most influential authors, while BMC Infectious Diseases and Frontiers in Cellular and Infection Microbiology were the primary publication venues. Keyword co-occurrence analysis identified "bacterial vaginosis," "women," and "inflammation" as the most frequent terms, while burst detection revealed emerging research trends in "lactobacillus," "intraepithelial neoplasia," and "16 s rRNA gene sequencing."
    Conclusion: This bibliometric analysis provides comprehensive insights into the evolution and current status of vaginal bacteria research in cervical cancer, highlighting key research themes and collaborative patterns. These findings offer valuable guidance for future research directions and potential clinical applications in cervical cancer prevention and treatment strategies.
    Keywords:  CiteSpace; VOSviewer; bacterial vaginosis; bibliometric analysis; cervical cancer
    DOI:  https://doi.org/10.3389/fmicb.2025.1615944
  24. Ann Med Surg (Lond). 2025 Aug;87(8): 4949-4962
    Insight into the research frontier of hypoxia in skin health and diseases: a bibliometric analysis.
    Cancan Huang, Xiang Li, Jieyu Li, Wenjun Wang, Xingzhu Mou, Wuda Huoshen, Ni Liu, Xia Xiong, Sha Yi, Guishu Zhong, Yan Chen.
      Research has demonstrated that hypoxia, a decrease in intracellular oxygen, is linked to multiple processes in the skin, including metabolic adaptation, cell survival, pathogenic microbe infection, immune response, tumorigenesis, and various diseases. This paper aims to perform a thorough bibliometric analysis of studies of hypoxia in skin health and disease to identify the frontiers, hotspots, and evolution of these studies. Articles about hypoxia in skin health and disease in the Web of Science Core Collection were gathered as of December 31, 2023. To find bursting keywords and references, VOSviewer was used to look at co-authorship and phrase co-occurrences and make visualizations of them. A total of 1511 papers on hypoxia in skin health and disease were examined in this study. China, the United States, and Japan were the top three countries contributing to this topic, while the International Journal of Molecular Sciences was the journal with the most articles. In terms of prolific authors in the publications, Yuesheng Huang from China contributed the most articles. The terms "hypoxia," "angiogenesis," and "wound healing" were the ones that were used the most frequently. In this study, a bibliometric analysis was performed on the last 10 years' worth of research on hypoxia in skin health and disease. The analysis identified the publications, nations, authors, institutions, and journals that were involved in this subject. These data offer a more comprehensive understanding of the area of research that has been conducted on hypoxia in skin health and disease.
    Keywords:  CiteSpace; VOS viewer; bibliometrics; hypoxia; skin
    DOI:  https://doi.org/10.1097/MS9.0000000000003303
  25. Orthop Surg. 2025 Aug 12.
    Research Trends in Immunomodulatory Therapy for Postmenopausal Osteoporosis: A Bibliometric Analysis.
    Wen Tang, Shenghui Yi, Janguo Liu, Huiming Chen, Zhijian Deng, Yongxia Zhang, Yang Luo, Yuehua Li.
      This bibliometric analysis investigates the research trends in immunomodulatory therapies for postmenopausal osteoporosis from 2000 to 2024. Utilizing 950 articles retrieved from the Web of Science Core Collection, we employed CiteSpace, VOSviewer, and R-based Bibliometrix to analyze publication dynamics, collaborative networks, and thematic evolution. Key findings include: (1) a steady rise in annual publications, peaking at 82 articles in 2024, with China (265 articles) and the United States (173 articles) as leading contributors. (2) Research hotspots centered on the RANKL/RANK/OPG pathway, T-cell-mediated inflammation (e.g., Th17/IL-17 axis), and emerging topics such as gut microbiota-bone axis and mesenchymal stem cell differentiation. (3) Clinical strategies prioritized denosumab (anti-RANKL) and IL-17 inhibitors, though long-term safety requires validation. (4) Institutional collaboration spanned continents, with Emory University, Harvard University, and Sichuan University as pivotal hubs. Keyword bursts revealed a shift from foundational mechanisms (e.g., TNF-α/IL-6 signaling) to translational topics like gene editing and precision medicine. Limitations include database bias (exclusive reliance on Web of Science) and undifferentiated clinical versus preclinical studies analysis. This study underscores the transformative potential of immunotherapies in osteoporosis management while advocating for multidisciplinary integration, expanded data sources, and rigorous clinical validation to address existing gaps.
    Keywords:  bibliometric analysis; immunomodulation; osteoimmunology; postmenopausal osteoporosis
    DOI:  https://doi.org/10.1111/os.70145
  26. Int J Dent. 2025 ;2025 8594730
    Bibliometric Analysis of Research Trends Related to the Publication of Clinical Trials on the Treatment of Temporomandibular Disorders Between 1973 and 2023.
    Yens Mendoza-Martiarena, Miguel Ángel Norabuena-Robles, Kilder Maynor Carranza-Samanez, Claudia Denisse Piscoche-Rodríguez.
      Objective: To perform a bibliometric analysis of clinical trials (CTs) that evaluated the effectiveness of treatments for temporomandibular disorders (TMDs) between 1973 and 2023. Materials and methods: This bibliometric study analyzed CT on TMD treatment identified in Scopus and Web of Science (WoS) databases through a query in MeSH terms. The main characteristics analyzed were year of publication, institutions, authors, citations, and keywords. Data were retrieved on March 18, 2024. VOSviewer and CiteSpace tools were used to create bibliometric networks and other visualizations. Results: A total of 559 CTs evaluating TMD treatments were identified. A remarkable growth was observed in the last 10 years, with USA, Brazil, and Turkey being the main contributors in publications. Conservative therapies (COTs) such as physiotherapy and the use of occlusal splints, together with minimally invasive therapies (MITs), such as joint level injections, were the most applied in recent years. The Journal of Oral and Maxillofacial Surgery and Cranio-Journal of Craniomandibular and Sleep Practice were the leading journals in the field and with an important number of citations. The University of São Paulo and Universidade Nove de Julho were the institutions with the highest contribution of CTs. The most prolific author had 12 publications. Conclusion: Clinical research on TMD treatments is extensive and growing; however, there are large differences in the number of CTs related to emerging therapies. Future studies should focus on the implementation of high-quality CTs by fostering international cooperations and expanding knowledge on emerging COTs and MITs.
    Keywords:  clinical trial; orofacial pain; temporomandibular disorder; temporomandibular joint
    DOI:  https://doi.org/10.1155/ijod/8594730
  27. Clin Exp Optom. 2025 Aug 10. 1-10
    Ranking of top 50 optometry academics in African universities by research impact.
    Samuel Kyei, Paul Owusu, Joseph Mannyeya Sa-Ambo, Gideon Owusu, Randy Asiamah, Rita Yelimaa Benyem, Pious Tawiah Amoako, Raphael Osei Owusu, Samuel Ankamah, Samuel Bert Boadi-Kusi.
       CLINICAL RELEVANCE: Optometry as a profession constitutes a distinct body of knowledge informed and sustained by evidence-based approaches derived from painstaking peer-reviewed scientific research publications.
    BACKGROUND: The contribution of African Optometric academics affiliated with African universities to the body of knowledge of the profession is yet to be assessed. This study sought to profile the research impact of African optometrists as a contribution to knowledge in the field of Optometry.
    METHODS: A structured bibliometric search was conducted on the Scopus database using a list of all Optometry training institutions in Africa and comprehensive optometry-related search terms.The resulting publications were systematically screened in two stages: (a) identification of articles directly related to optometry and (b) identification of the authors of those optometry-related publications who are optometrists affiliated with optometry schools in Africa. The authors were then ranked based on h-index, research productivity, citation metrics, and publication rate. The final data was extracted on 31 March 2025.
    RESULTS: The Top 50 African Optometric academics ranked by research impact have h-indices ranging from 5 to 52 and have published between 8 and 166 papers. Eleven (22%) are women. Kovin Shunmugam Naidoo is the most impactful researcher on the African continent, with the highest h-index of 52 and a citation count of 64,357. The most prolific author is William Frith Harris (166 papers). Uchechukwu Levi Osuagwu and Mutali Musa have the fastest publishing rate (11.3 papers per year). The active publication years ranged from 2 to 29 years, with a median of 10 years.
    CONCLUSION: African optometric academics have made moderate contributions to optometry literature, and their shorter active publication years depict a great potential for further contributions over time. The 50 most impactful optometrists in Africa are identified for collaboration and partnership.
    Keywords:  Africa; citations; h-index; optometrists; publication metrics; research ranking
    DOI:  https://doi.org/10.1080/08164622.2025.2540350
  28. J Stomatol Oral Maxillofac Surg. 2025 Aug 09. pii: S2468-7855(25)00309-X. [Epub ahead of print] 102523
    Global Trends of teaching methodologies in Oral and Maxillofacial Surgery Education:A 30-Year Bibliometric Analysis.
    Youming Luo, Yilin She, Zhen Li, Nan Jiang.
       PURPOSE: Revise: To analyze 30-year global trends in Oral and Maxillofacial Surgery(OMS) education research through bibliometrics, assessing publication patterns, key contributors, and emerging teaching methodologies.
    METHODS: Revise: The study analyzed publications on teaching methodologies in oral and maxillofacial surgery within the Web of Science Core Collection, covering the period from 1994 to 2024. A systematic compilation methodology was employed, including rigorous literature retrieval with specific inclusion and exclusion criteria, data cleaning using CiteSpace software to eliminate redundant entries, and comprehensive analysis using multiple tools such as Microsoft Excel for data management, Bibliometric Online Analysis Platform for inter-country collaboration visualization, R software for geospatial data visualization, CiteSpace for constructing visual networks of various elements, and Origin for annual publication analysis. Using these tools, we conducted a bibliometric analysis and visualization of teaching methodologies in this surgical field.
    RESULTS: The number of relevant publications in this research area demonstrates a fluctuating yet overall upward trend, totaling 248 articles and 15 reviews. These contributions originate from 37 countries, 41 institutions, and involve 1,306 authors. The USA, UK, and Germany are the leading contributors. Most articles were published in the "Journal of Oral and Maxillofacial Surgery." Key authors include Robert Sader, Lukas B. Seifert, and Jasmina Sterz, while Frank Hoelzle has the most influence. The predominant keywords are "skills," "experience," and "competence."
    CONCLUSION: The bibliometric analysis of oral and maxillofacial surgery education highlights a dynamic field with a rising global scholarly interest. The USA, UK, and Germany lead in research contributions, and diverse teaching methods, from traditional lectures to cutting-edge simulations, -playing a crucial role in student development. Despite the challenges, such as resource constraints and the need for technological advancement, the integration of these methods and the adoption of innovative technologies are pivotal for advancing OMS education. This comprehensive approach is essential for equipping future surgeons with the competencies required to thrive in the complex and evolving field of oral and maxillofacial surgery.
    Keywords:  Bibliometric; Oral and maxillofacial surgery; Oral and maxillofacial surgery resident; Teaching methodologies
    DOI:  https://doi.org/10.1016/j.jormas.2025.102523
  29. J Orthop Surg (Hong Kong). 2025 May-Aug;33(2):33(2): 10225536251366814
    Global research trends in AI-related foot and ankle surgery research: A bibliometric and visualized study.
    Liyi Zhang, Hui Du.
      BackgroundArtificial intelligence (AI) has experienced rapid advancements leading to numerous applications in foot and ankle surgery. This study aimed to assess the current status, research trends, and future directions of AI in foot and ankle surgery and to identify emerging hotspots in this field.MethodsRelevant publications on AI in foot and ankle surgery were retrieved from the Web of Science Core Collection database up to December 31, 2024. A bibliometric analysis was conducted, and data visualization was performed using VOSviewer and CiteSpace.ResultsA total of 2047 publications from 1999 to 2024 were included. The number of AI-related studies in foot and ankle surgery has shown a steady annual increase. China (581 publications, H-index = 47) and the United States (489 publications, H-index = 53) are the leading contributors in terms of publication volume and research impact. Keyword co-occurrence analysis indicates that AI research in this field has progressed from foundational algorithms to the study of lower limb kinematics and clinical disease applications. Keyword burst analysis highlights diabetic foot ulcers and computer-aided diagnosis as key research focuses and emerging hotspots for future investigation.ConclusionAI research in foot and ankle surgery has expanded rapidly, with China and the United States at the forefront. The field has evolved from algorithm development to applications in lower limb kinematics and clinical disease management, with diabetic foot ulcers and computer-aided diagnosis identified as major areas of future research.
    Keywords:  ankle; artificial intelligence; bibliometric; foot
    DOI:  https://doi.org/10.1177/10225536251366814
  30. Medicine (Baltimore). 2025 Aug 08. 104(32): e43790
    Exploring the relationship between intestinal immunity and obesity: A bibliometric and knowledge-map analysis.
    Shanshan Cui, Shuai Shang, Zihui Yan.
       BACKGROUND: This study aimed to identify influential researchers, institutions, and countries and reveal the evolution of research hotspots and themes in the field of the relationship between intestinal immunity and obesity through bibliometric analysis.
    METHODS: We searched and selected the Web of Science database for publications on intestinal immunity and obesity between 2004 and 2024, followed by bibliometric and visualization analysis using CiteSpace, GraphPad Prism 8, Gephi, and Charticulator.
    RESULTS: A total of 3333 publications involving 16,144 authors, 3372 research institutions, and 97 countries or regions were analyzed. The United States led in both total publication counts and betweenness centrality. The influential institutions in this field were the Institut national de la santé et de la recherche médicale and the University of Reading, which ranked first in publication output and betweenness centrality, respectively. Patrice D. Cani was the most influential researcher. Research on the relationship between intestinal immunity and obesity mainly focused on the pathogenesis of obesity and obesity-related diseases. Academic attention to obesity pathogenesis shifted from innate to adaptive immunity and transitioned from gut dysbiosis to microbial metabolites. Meanwhile, obesity-related diseases evolved from intestinal disorders to metabolic dysfunction-related cardiovascular diseases and liver diseases. The research themes in this field evolved through 3 stages: the early stage focused on investigating the mechanisms of obesity and its complications through gut research; the middle stage concentrated on the impact of intestinal inflammation and gut microbiota on obesity onset and progression; and the recent stage emphasized the development of specific microbiota or metabolites and the role of certain immune cell populations in the development of obesity.
    CONCLUSION: Over the past 20 years, research on intestinal immunity and obesity has experienced the initial rapid expansion, stabilization period, and current breakthrough period. The in-depth application of multi-omics analysis and artificial intelligence, as well as the development of gene editing technology, may provide new ideas for targeted modulation of specific intestinal immune cells or microbes for obesity treatment, which may be the main direction of future research in this field.
    Keywords:  bibliometric analysis; intestinal immunity; obesity
    DOI:  https://doi.org/10.1097/MD.0000000000043790
  31. Front Insect Sci. 2025 ;5 1625155
    Research progress and trends of insect high-temperature stress: insights from bibliometric analysis.
    Jiapeng Li, Xianting Wang, Rui Guo, Zikun Li, He Lv, Yiping Wang.
      Climate warming, particularly extreme temperature events, poses a major threat to insect survival and diversity. Thus, understanding insect responses to high temperatures is increasingly important for predicting their resilience and distribution under climate change. In this study, we analyzed 4,417 articles from the Web of Science Core Collection using VOSviewer, CiteSpace, and the Bibliometrix R package. The results show that since 2012, the number of publications on insect responses to high temperatures has been increasing year by year at an average annual growth rate of 3.5%, reflecting the increasing research interest in this field. Secondly, the response of insects to high temperatures is a multidisciplinary research field. The PLoS One journal has the largest quantity of published articles, boasting the highest total citations and H-index globally. Hoffmann AA and Du YZ are the most productive authors. Furthermore, keyword analysis revealed research focus on molecular responses such as gene expression and heat-shock proteins. Cluster analysis of bibliographic coupling identified 15 major research themes, results demonstrate that the field evolved from describing physiological traits to dissecting biochemical and reproductive mechanisms underlying thermal tolerance, aiming to uncover biological responses and adaptive strategies under heat stress. To summarize, this study provides an overview of current research trends and emerging priorities in insect heat stress biology.
    Keywords:  bibliometrics; climate change; global warming; hot spots and frontiers; insect
    DOI:  https://doi.org/10.3389/finsc.2025.1625155
  32. Discov Oncol. 2025 Aug 12. 16(1): 1536
    Mapping the future: bibliometric analysis of omics research trends in non-small cell lung cancer.
    Yanqian Zhu, Jiawei Chen, Yufei Wang, Jinyang Hu, Chen Gao, Linyu Wu.
       PURPOSE: Omics technologies, such as genomics, transcriptomics, proteomics, and radiomics, play an increasingly important role in the diagnosis and treatment of non-small cell lung cancer (NSCLC). It is, therefore, essential to unveil the research landscape and future trends of relevant research. This study aims to explore the research fields based on omics technologies in NSCLC, elucidating the research status, hotspots, and trends from a bibliometric perspective.
    METHODS: The Web of Science Core Collection was utilized to retrieve relevant publications in omics technologies and their applications in NSCLC. By using the bibliometric methods and tools ("bibliometrix" R package, VOSviewer, and CiteSpace), data and visualized analyses for annual publication outputs, countries, institutions, authors, journals, references, and keywords proceeded.
    RESULTS: A total of 5,337 publications were involved in our analysis. These articles, written by 32,286 authors, originated in 5,863 institutions from 82 countries and were published in 797 journals. The Journal of Thoracic Oncology and Clinical Cancer Research were representative journals in omics-based research in NSCLC. "Survival," "adenocarcinoma," "mutation," "epidermal growth factor receptor," "resistance," and "chemotherapy" were the highest-frequency keywords. Liquid biopsy and deep learning were also trending topics in omics-related research, according to keyword clustering, trend topics, and citation burst analysis.
    CONCLUSION: Omics technologies, including genomics, transcriptomics, and proteomics, were widely used in the diagnosis, prognosis, and treatment of NSCLC. And innovative methods, including liquid biopsy and deep learning, demonstrate a profound impact on advancing the understanding and treatment strategies for NSCLC and warrant further investigation.
    Keywords:  Bibliometric analysis; Non-small cell lung cancer; Omics; Visualized study
    DOI:  https://doi.org/10.1007/s12672-025-03140-8
  33. Naunyn Schmiedebergs Arch Pharmacol. 2025 Aug 15.
    Neutrophil extracellular traps in cardiovascular disease: a bibliometric analysis (2005-2024).
    Li-Mei Liang, Xing Chen, Yan Deng.
      Cardiovascular disease (CVD) has consistently posed a significant challenge in the medical field. Currently, they remain a leading cause of premature mortality. In recent years, the growing recognition of neutrophil extracellular traps (NETs) has revealed their significant involvement in the pathogenesis of CVD. Athorough search was carried out within the Web of Science Core Collection database for articles and reviews pertaining to CVD and NETs, including those published between January 2005 and December 2024. The collected literature was then subjected to bibliometric and visual analyses, utilizing the Citespace and VOSviewer software applications. A total of 1,014 relevant publications were identified, accompanied by a cumulative citation count of 48,955 across all included studies. The United States and China lead with the most extensive research output in this field, with the highest number of publications appearing in the International Journal of Molecular Sciences. Literature and keyword analysis indicate a burgeoning research interest in the interplay between NETs and various diseases, including atherosclerosis, myocardial infarction, and deep vein thrombosis, as well as in thrombotic mechanisms involving platelets, tissue factor, coagulation cascades, and endothelial injury. This paper delineates the research hotspots and cutting-edge frontiers concerning the pivotal role of NETs in the pathogenesis of CVD, as well as the application of therapeutic strategies targeting NETs in CVD. It provides novel insights into the functions of NETs within the context of cardiovascular disorders.
    Keywords:  Bibliometric; Cardiovascular disease; Neutrophil extracellular traps; Thrombosis; Visualization
    DOI:  https://doi.org/10.1007/s00210-025-04507-y
  34. Nanomaterials (Basel). 2025 Aug 06. pii: 1205. [Epub ahead of print]15(15):
    Current Research Trends and Hotspots in Radiotherapy Combined with Nanomaterials for Cancer Treatment: A Bibliometric and Visualization Analysis.
    Muyasha Abulimiti, Shiqin Dai, Ebara Mitsuhiro, Yu Sugawara, Yinuo Li, Hideyuki Sakurai, Yoshitaka Matsumoto.
      This study investigated the evolving trends, current research hotspots, and future directions of radiotherapy combined with nanobiomaterials through a bibliometric analysis. Publications related to nanobiomaterials used in radiotherapy between 2004 and 2024 were retrieved from the Web of Science Core Collection database and analyzed using VOSviewer, R, and CiteSpace. China emerged as the leading contributor, accounting for 1051 publications (50.41%), followed by the USA. Liu Zhuang is the most productive author in this field. American Chemical Society (ACS) Nano published the most influential articles and accumulated the highest number of citations. Advanced Targeted Therapies in Cancer: Drug Nanocarriers, the Future of Chemotherapy was the most cited, with 1255 citations. Citation bursts have revealed emerging research trends in targeted delivery, cellular studies, co-delivery strategies, immunogenic cell death, polymeric nanoparticles, tumor research, and drug delivery systems, indicating potential avenues for future research. Over the past two decades, nanomaterials for radiotherapy have gained substantial attention. Key areas of focus include enhancing the efficacy of radiotherapy, achieving targeted drug delivery, minimizing adverse effects, and integrating nanomaterials with other therapeutic modalities. Future investigations are expected to improve the precision of radiotherapy, augment radiation effects, and optimize the tumor microenvironment.
    Keywords:  cancer; drug delivery; nanobiomaterials; nanomaterials; radiotherapy
    DOI:  https://doi.org/10.3390/nano15151205
  35. Front Neurol. 2025 ;16 1659391
    Correction: Narcolepsy: a machine learning bibliometric analysis (1996-2024).
    Minheng Zhang, Xiaodong Hu, Haiyan Wu, Haixia Fan.
      [This corrects the article DOI: 10.3389/fneur.2025.1505574.].
    Keywords:  bibliometric analysis; comorbidities; molecular mechanisms; narcolepsy; treatment
    DOI:  https://doi.org/10.3389/fneur.2025.1659391
  36. Front Med (Lausanne). 2025 ;12 1621079
    Bibliometric analysis of research hotspots and emerging trends in mitophagy and atherosclerosis (2004-2024).
    Shuchen Ding, He Zhang, Luxia Song, Xinyi Wang, Lifang Song, Wende Tian, Xuanye Chen, Hao Xu.
       Background: Mitophagy is closely involved in the onset, progression and pathological mechanisms of atherosclerosis. This study set out to provide a comprehensive overview and identify emerging research trends in the field.
    Methods: A systematic literature retrieval was conducted across the Web of Science Core Collection (WoSCC) for publications spanning 2004 to 2024. Bibliometric analyses and knowledge mapping were performed utilizing CiteSpace, VOSviewer, R-Bibliometrix, Scimago Graphica and Excel to evaluate the intellectual landscape of the field.
    Results: The analysis reveals a fluctuating but overall increasing trend in annual publications. The United States and China are the primary contributors to the body of research, with leading institutions predominantly located in China, the United States, and Russia. Notably, the works of Orekhov AN stand out in terms of both quantity and quality. The most cited studies is Forrester SJ's 2018 publication in Circulation Research. Additionally, keyword analysis highlights the prevailing research hotspots, including: (1) key molecules such as NF κB, NLRP3 inflammasome, and mitochondrial DNA; (2) critical pathological processes such as oxidative stress, mitochondrial dysfunction, and mitochondrial dynamics; and (3) and the role of mitophagy within vascular smooth muscle cells, endothelial cells, and macrophages in the pathogenesis of atherosclerosis.
    Conclusion: The study of mitophagy in atherosclerosis has garnered increasing attention, with substantial progress made in understanding its molecular and cellular mechanisms. This work highlights the current research hotspots and identifies prospective directions for future exploration. Further investigation into the intricate mechanisms governing mitophagy may uncover novel therapeutic strategies that could mitigate the progression of atherosclerosis.
    Keywords:  atherosclerosis; bibliometrics; mitophagy; molecules; pathological process
    DOI:  https://doi.org/10.3389/fmed.2025.1621079
  37. J Thorac Dis. 2025 Jul 31. 17(7): 5309-5319
    Percutaneous versus surgical tracheostomy in mechanically ventilated ICU patients: a bibliometric review and visual analysis (1990-2024).
    Raffaele Merola, Stefania Troise, Federica Calabria, Carmine Iacovazzo, Antonio Romano, Maria Vargas.
       Background: Tracheostomy is a frequently performed procedure for critically ill patients requiring prolonged mechanical ventilation. This study aims to analyze the literature comparing percutaneous and surgical tracheostomy techniques using bibliometric methods to explore trends in research, key contributors, and clinical outcomes.
    Methods: A bibliometric analysis was conducted on publications comparing percutaneous and surgical tracheostomy using the Scopus database. Data on publication trends, authorship, citations, and co-occurrence of keywords were analyzed using VOSviewer software.
    Results: A total of 51 articles were included, focusing on the safety, efficacy, and outcomes of the two techniques. The analysis revealed a steady increase in publications over the past two decades, with recent studies expanding to compare patient quality of life and healthcare resource utilization. Key authors such as Dulguerov et al. and institutions like the University of Geneva and University of Zurich were identified as significant contributors. The most cited paper was "Percutaneous or surgical tracheostomy: A meta-analysis" by Dulguerov et al. (Critical Care Medicine, 1999). Critical Care Medicine emerged as the most active and cited journal. The paper titled "Comparative clinical trial of standard operative tracheostomy with percutaneous tracheostomy" by Hazard et al., published in Critical Care Medicine in 1991, was the most cited reference.
    Conclusions: The bibliometric analysis of publications comparing percutaneous and surgical tracheostomy, although limited to a single database search, provides a fairly comprehensive overview of the available literature on the topic.
    Keywords:  Airway management; bibliometrics; mechanical ventilation; tracheostomy
    DOI:  https://doi.org/10.21037/jtd-2025-306
  38. Disaster Med Public Health Prep. 2025 Aug 13. 19 e238
    Bibliometric Insights into Human Metapneumovirus Interventions: Trends, Gaps, and Future Directions.
    Sridevi Gnanasekaran, Vignesh Murugan, Surendran Venkataraman, Vinoth Rajendran, Jayaraj Vinothini, Kavita Vasudevan.
       BACKGROUND: Human metapneumovirus (HMPV) is a significant cause of respiratory tract infections, particularly in young children, the elderly, and immunocompromised individuals. Despite its global impact, research on therapeutic, diagnostic, and preventive interventions remains fragmented. This study conducts a bibliometric analysis to evaluate global trends, advancements, and gaps in HMPV intervention research.
    METHODS: Bibliometric data were retrieved from the Scopus database using keywords related to HMPV interventions, including "treatment," "vaccine," and "diagnostics," for the period 2000-2025. Data were analyzed using Biblioshiny, the graphical interface of the Bibliometrix R package. Descriptive metrics, keyword analysis, thematic evolution, and collaboration networks were assessed, with results visualized as charts, maps, and network diagrams.
    RESULTS: A total of 2482 publications were analyzed. Research output accelerated markedly after 2015, driven by advances in molecular diagnostics and global interest in respiratory viruses. The United States, the United Kingdom, and China emerged as leading contributors, while low- and middle-income countries (LMICs) remained underrepresented. The most productive journals were Journal of Clinical Virology and Journal of Medical Virology. Prominent themes included vaccine development, antiviral therapies, and molecular diagnostics. However, key research gaps were identified in the areas of coinfections, long-term sequelae, and interventions tailored for high-risk and resource-limited populations. Collaboration networks highlighted concentrated partnerships among high-income countries, indicating limited global equity in HMPV research.
    CONCLUSION: While progress in HMPV research is evident, critical disparities remain in global collaboration and focus areas. Future efforts should prioritize inclusive partnerships, increased research in LMICs, and the development of affordable diagnostic and therapeutic solutions. This bibliometric analysis serves as a roadmap to guide equitable and impactful global HMPV research.
    Keywords:  bibliometric analysis; human metapneumovirus; interventions; research gaps; respiratory infections
    DOI:  https://doi.org/10.1017/dmp.2025.10175
  39. Ann Med Surg (Lond). 2025 Aug;87(8): 4988-4996
    Global status and research trends of combined heart and lung transplantation: a bibliometrics analysis.
    Jian Huang, Guangcheng Sun, Caiwei Li, Chuankai Zhang, Jiwei Qin, Xianliang Jiang, Li Ke.
       Background: Combined heart and lung transplantation represents a critical therapeutic approach for addressing end-stage cardiac and pulmonary diseases. This study seeks to conduct a comprehensive analysis of the global literature on combined heart and lung transplantation from 1980 to 2024, with the objective of identifying key research trends and emerging areas of interest within this domain.
    Method: A systematic search and compilation of bibliometric data related to combined heart and lung transplantation, published between 1980 and 2024, was conducted using the Web of Science Core Collection. Subsequent bibliometric and knowledge mapping analyses were performed utilizing CiteSpace 6.1.R6 (Basic) and VOSviewer (1.6.18).
    Results: A total of 1746 articles were retrieved, indicating a stable upward trend in the field of combined heart and lung transplantation, particularly in the number of published papers over the past two decades. The United States leads in the number of published articles (1066), followed by Germany (155) and the United Kingdom (140). In terms of keyword analysis, the most frequently used keywords are "lung transplantation" (226), "transplantation" (172), and "survival" (146). An analysis of cited keywords reveals that "severe combined immunodeficiency" was the most prominent keyword prior to 2000, whereas "Outcome" has emerged as the most significant keyword since 2000.
    Conclusion: Over the past four decades, the field of combined heart and lung transplantation has undergone consistent and rapid advancement. The findings from this bibliometric analysis offer valuable insights and serve as a reference point for future research endeavors and for stakeholders engaged in this area.
    Keywords:  CiteSpace; VOSviewer; bibliometric; combined heart and lung transplantation
    DOI:  https://doi.org/10.1097/MS9.0000000000003472
  40. Int Urogynecol J. 2025 Aug 16.
    Bibliometric Mapping of Neovagina Creation Research: Trends, Themes, and Global Collaborations.
    Melisa Golgelioglu, Gulcan Akverdi.
       INTRODUCTION AND HYPOTHESIS: Neovagina creation is an essential area of research in gynecological and reconstructive surgery, addressing congenital conditions like Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome and transgender health needs. This study aims to provide a comprehensive bibliometric analysis of global research trends, influential contributors, and thematic developments in this evolving field.
    METHODS: Data were retrieved from the Web of Science Core Collection, encompassing 357 publications from 56 countries. Bibliometric tools, including VOSviewer, were used to analyze publication trends, author and institutional contributions, and keyword co-occurrences. The study also visualized global collaborations and thematic patterns.
    RESULTS: The United States and Italy emerged as the leading contributors, reflecting their advanced research infrastructure and resources. Frequently occurring keywords, including "neovagina," "vaginal agenesis," and "Mayer-Rokitansky-Küster-Hauser syndrome," highlighted the focus on congenital conditions and surgical reconstruction. Time-series analysis revealed increasing attention to uterus transplantation and transgender health since 2018. However, the study identified limited contributions from low-resource regions and insufficient international collaboration.
    CONCLUSIONS: This analysis highlights the evolving landscape of neovagina creation research, driven by multidisciplinary approaches and thematic diversity. While significant progress has been made, global disparities and research gaps remain. Addressing these issues through international collaborations and equitable research initiatives is critical to advancing clinical practices and improving outcomes for all patients requiring neovagina creation.
    Keywords:  Mayer–Rokitansky–Küster–Hauser syndrome; Neovagina creation; Transgender health; Vaginal agenesis
    DOI:  https://doi.org/10.1007/s00192-025-06287-8
  41. J Eval Clin Pract. 2025 Aug;31(5): e70234
    Bibliometric and Visual Analysis of Research in Food Insecurity and Malnutrition.
    Nurhayat Tugra Ozer, Izzet Ulker.
       AIMS: Food insecurity (FI) is defined as a multifaceted condition encompassing limited or uncertain access to safe food, adequate availability, utilization, and stability of nutritionally appropriate foods-shaped by economic disadvantage, social inequities, climate shocks, and health crises like epidemics. It is particularly prevalent among vulnerable populations and directly drives malnutrition as well as other adverse health outcomes. The aim of this study is to provide a comprehensive overview of the evolution of research on FI and its linkage to malnutrition, identifying principal authors, scientific collaborations, and thematic trends.
    METHODS: A bibliometric analysis was conducted of 570 relevant articles indexed in Web of Science (1991-2024), focusing on original research examining the FI-malnutrition nexus. The R package programme, VOSviewer, and WOS analytical tools were employed for data extraction, network analysis, and visualization.
    RESULTS: The analysis revealed an annual growth rate of 8.87%, with publication output surging after 2009 and peaking in 2020 (55 articles). The USA dominated research production (n = 232 studies), yet 47.89% of studies involved international collaborations, primarily targeting low- and middle-income populations. The average citation rate was 28.0 per article, with thematic shifts toward HIV/AIDS (post-2009) and COVID-19 (post-2019) alongside persistent focus on poverty.
    CONCLUSIONS: FI-malnutrition research is shaped by both structural drivers (poverty, inequality) and health crises (HIV, COVID-19). Despite geographic disparities in research leadership (Global North) versus study populations (Global South), the field shows strong cross-border collaboration-highlighting opportunities for more equitable partnerships.
    Keywords:  Bibliometric; Food security; Global health; Health disparities; Nutritional status
    DOI:  https://doi.org/10.1111/jep.70234
  42. Regen Ther. 2025 Dec;30 544-557
    Hydrogel in musculoskeletal diseases: Unraveling trends, research foci, and future trajectories via bibliometric insights (from 2000 to 2025).
    Weibei Sheng, Siyang Cao, Haotian Qin, Peng Liu, Deli Wang, Jian Weng, Hui Zeng, Fei Yu.
       Introduction: Hydrogels, owing to their excellent biocompatibility, tunable physicochemical properties, and ability to mimic the extracellular matrix, have emerged as promising materials for the treatment of musculoskeletal disorders, including osteoarthritis, intervertebral disc degeneration, and bone injuries. Recent advancements in smart hydrogels and multifunctional composites have further broadened their applications in drug delivery, tissue engineering, and regenerative medicine. However, despite growing interest in this field, current reviews often lack systematic, data-driven insights into the evolving research landscape.
    Methods: To address this gap, we conducted a bibliometric analysis using CiteSpace and VOSviewer to quantitatively map the development of hydrogel-related research in musculoskeletal disorders over the past two decades. Key parameters analyzed included publication trends, influential countries and institutions, collaborative networks, keyword evolution, and research hotspots.
    Results: Our analysis revealed a steady growth in publications, with China and the United States emerging as leading contributors. Prominent institutions and authors were identified, along with landmark publications that have shaped the field. Keyword co-occurrence analysis highlighted emerging themes such as injectable hydrogels, 3D bioprinting, and osteochondral regeneration. The most frequently studied disease targets included osteoarthritis, intervertebral disc degeneration, and bone defect repair.
    Conclusions: This comprehensive bibliometric overview offers valuable insights into the current status and future directions of hydrogel research in musculoskeletal disorders. It highlights key trends, influential contributors, and emerging hotspots, providing a solid foundation for advancing interdisciplinary collaborations and accelerating the clinical translation of hydrogel-based therapies.
    Keywords:  Bibliometric analysis; Cartilage regeneration; Drug delivery; Hydrogels; Musculoskeletal disorders; Tissue engineering
    DOI:  https://doi.org/10.1016/j.reth.2025.08.002
  43. J Multidiscip Healthc. 2025 ;18 4675-4690
    Integrating Bibliometrics and Bioinformatics to Map Knowledge Structure, Trends, and Genetic Insights in Polycystic Ovary Syndrome and Tumors (2015-2024).
    Meng Liu, Ying Xiong, Shao-Hua Zhang, Jun Yuan, Zhi-Qiang Cheng.
       Objective: This study aims to construct a knowledge map of polycystic ovary syndrome (PCOS)-cancer research through bibliometric analysis to elucidate its developmental trajectory and global research landscape, and further employ bioinformatics approaches to investigate the underlying molecular mechanisms linking PCOS and related cancer.
    Methods: Utilizing the Web of Science Core Collection as the data source, English-language publications from 2015 to 2024 were retrieved. CiteSpace and VOSviewer were employed for co-occurrence analysis, co-citation network construction, cluster identification, and keyword burst detection. PCOS and endometrial cancer-related genes were extracted from the Genecards database, followed by screening of overlapping genes for protein-protein interaction (PPI) network analysis to identify key targets. Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis was performed to pinpoint critical signaling pathways.
    Results: Publications on PCOS and cancer exhibited a significant and steady growth over the past decade, with the United States and China demonstrating prominent contributions in both output volume and collaborative networks. Frontiers in Endocrinology and Gynecological Endocrinology jointly ranked first in publication count, while The Journal of Clinical Endocrinology & Metabolism received the highest citations. Keyword co-occurrence cluster analysis revealed major research hotspots including endometrial cancer, gene expression, and cardiovascular disease. Bioinformatics analysis identified 250 overlapping genes between PCOS and endometrial cancer. PPI network analysis highlighted TP53 as the most critical hub gene, and KEGG enrichment analysis underscored the pivotal role of the PI3K/AKT signaling pathway.
    Conclusion: By integrating bibliometric analysis with bioinformatics, this study systematically maps the knowledge structure, emerging trends, and molecular mechanisms linking PCOS and cancer. Our findings specifically highlight the association between PCOS and endometrial cancer, may driven by dysregulation of the TP53 and PI3K/AKT signaling pathways. This work provides valuable insights for researchers to understand the foundational knowledge framework, identify emerging trends, potential collaborators, and mechanistic targets for future studies.
    Keywords:  CiteSpace; PI3K/AKT signaling pathway; VOSviewer; bibliometric analysis; cancer; polycystic ovary syndrome
    DOI:  https://doi.org/10.2147/JMDH.S536122
  44. Front Pediatr. 2025 ;13 1611345
    Paradigm shifts in neonatal hypoxic-ischemic encephalopathy therapeutics: a four-decade bibliometric exploration of emerging therapeutic dimensions (1985-2024).
    Juntao Shu, Ling Liu, Mei Yuan, Mingbiao Ma, Jingjing Yang.
       Aim: Neonatal hypoxic-ischemic encephalopathy (HIE) remains a significant cause of neonatal morbidity and mortality worldwide, necessitating the exploration of effective therapeutic interventions. Current treatment strategies primarily involve therapeutic hypothermia (TH); however, its efficacy remains inconsistent. Research topics and trends in this area remain unclear as well. This study aimed to identify key research areas, collaboration networks, and emerging trends using bibliometric analysis tools.
    Methods: A comprehensive analysis was conducted on 1,165 records from the Web of Science Core Collection (WoSCC) database. Various bibliometric techniques were employed, including coauthor analysis, co-occurrence analysis, co-citation analysis, reference clustering, and topic modeling, to visualize the knowledge structure and research dynamics in the HIE field.
    Results: The findings revealed extensive collaboration networks among authors, institutions, and countries, highlighting global efforts to address this critical neonatal condition. Recent trends identified key research areas, including TH, mild systemic hypothermia, oxidative stress, biomarkers and signaling pathways, which are essential for advancing the understanding and treatment of HIE.
    Conclusion: This study provides valuable insights into the current TH for neonates with HIE. Future research should focus on optimizing treatment approaches and evaluating long-term efficacy to enhance clinical applications.
    Keywords:  bibliometric analysis; biomarkers; emerging treatments; hypoxic-ischemic encephalopathy; signaling pathways; therapeutic hypothermia
    DOI:  https://doi.org/10.3389/fped.2025.1611345
  45. Ecol Evol. 2025 Aug;15(8): e71952
    Global Remote Sensing Research: An Author-Centric Analysis of Contributions and Trends.
    Ehsan Rahimi, Chuleui Jung.
      Remote sensing research stands at a critical juncture, grappling with challenges in identifying shifting trends and emerging scientific priorities. These gaps limit the field's ability to effectively address pressing environmental issues and foster innovation in related applications, particularly in conservation. In this study, we conducted a comprehensive scientometric analysis of approximately 20,000 researchers identified via Google Scholar who explicitly list "remote sensing" in their profiles, examining their publication trends, citation patterns, collaboration networks, and disciplinary affiliations. The analysis utilized a dataset comprising over 837,658 publications and nearly 20 million citations spanning from 1700 to 2024. Our findings reveal that each researcher has accumulated an average of 1435 citations, with a mean H-index of 10.9 and an i10-index of 17.4. Collaboration plays a pivotal role in the field, as evidenced by 79% of citations originating from co-authored works. The peak of scientific output was observed in 2022, with 54,304 publications-the highest annual total recorded. However, a slight decline was noted in 2024, with 50,096 papers published. Citations per paper peaked in the mid-2010s, reaching their highest levels between 2015 and 2020. In contrast, recent years have witnessed a marked decline, with total citations dropping from over 1.1 million in 2020 to 317,585 in 2023 and just 84,389 in 2024. Keyword analysis identified "classification," "climate," "forest," "land," and "mapping" as dominant themes, reflecting the field's continued focus on addressing global environmental challenges. While the sustained growth in publication output underscores the dynamism of remote sensing research, the declining citation counts suggest a shift toward highly specialized studies that appeal to narrower audiences. This trend necessitates a strategic reassessment of research priorities and publishing practices to ensure that remote sensing studies maintain their relevance and impact in addressing urgent global challenges.
    Keywords:  citation analysis; climate change; forests; google scholar; network analysis; trend analysis
    DOI:  https://doi.org/10.1002/ece3.71952
  46. Ir J Med Sci. 2025 Aug 11.
    Open access vs. subscription: comparing the impact of journals in physical therapy and rehabilitation.
    Elif Ozyigit, Mustafa Hüseyin Temel, Fatih Bağcıer.
       BACKGROUND: Open access (OA) and subscription-based (SB) journals are key models in academic publishing. OA journals focus on accessibility, while SB journals often emphasize subscription revenue, leading to variations in metrics such as impact factor and citation performance.
    AIM: To compare metrics of OA and SB physical therapy and rehabilitation journals using Scimago Journal & Country Rank (SJCR).
    METHODS: The study analyzed 266 journals, including 92 OA and 174 SB journals. Metrics such as impact factor, H-index, Scimago Journal Rank (SJR), total citations, citations-to-documents ratio, quartile rankings, and article processing charges (APCs) were examined.
    RESULTS: SB journals showed significantly higher H-index values (p < 0.001). Higher APCs in OA journals were strongly correlated with higher impact factors (r = 0.703, p < 0.001), SJR (r = 0.727, p < 0.001), total citations (r = 0.586, p < 0.001), and H-index (r = 0.520, p < 0.001). Quartile rankings indicated better performance for OA journals (p < 0.05).
    CONCLUSION: While SB journals exhibited higher H-index values, OA journals performed similarly in other metrics. The correlation between higher APCs and improved performance in OA journals underscores the role of financial investment. Both models are crucial for disseminating research in physical therapy and rehabilitation, highlighting the importance of editorial standards and rigorous peer review.
    Keywords:  Academic publishing; Journal metrics; Open access journal; Physical therapy; Rehabilitation; Subscription-based journal
    DOI:  https://doi.org/10.1007/s11845-025-04038-8
  47. Naunyn Schmiedebergs Arch Pharmacol. 2025 Aug 14.
    Global research hotspots, trends, and future directions of ivermectin research: an informatics investigation (2020-2025).
    Siddig Ibrahim Abdelwahab, Manal Mohamed Elhassan Taha, Khaled A Sahli, Moath Mohamed Farasani, Marwa Qadri, Abdulaziz Alarifi, Amani Khardali, Khloud H Alsaadi, Abdullah Farasani, Nizar A Khamjan, Jobran M Moshi, Saeed Alshahrani, Ahmad Assiri.
      Ivermectin, a widely used antiparasitic drug, gained global attention during the COVID-19 pandemic for its proposed antiviral effects. This study explores how ivermectin research evolved between 2020 and 2025, identifying key trends, emerging topics, and thematic changes. A data-driven bibliometric and informatics-based analysis was conducted using the Scopus database. Original articles were examined through advanced co-citation, co-word, and bibliographic coupling techniques. We employed artificial intelligence-enabled clustering algorithms, including Walktrap and hierarchical models, using tools such as VOSviewer and Bibliometrix (R package), to explore the conceptual landscape and research dynamics. A total of 1,041 ivermectin-related articles were included. Research topics shifted from antiparasitic and veterinary uses to newer areas like COVID-19 treatment, drug repurposing, oxidative stress, and vector control. We identified 12 thematic clusters and six co-word clusters. Although citation impact declined after 2021, interest remained strong in molecular and pharmacological mechanisms. Key authors, journals, and studies were also identified. This is the first AI-enhanced bibliometric mapping of ivermectin literature in the post-pandemic era. The findings uncover underexplored but promising research directions-such as apoptosis, immunomodulation, and nanodelivery-and highlight the added value of machine learning tools in uncovering complex thematic transitions and research frontiers. This approach offers deeper insights than traditional bibliometric methods by uncovering nuanced thematic transitions through AI-powered clustering.
    Keywords:  COVID-19; Drug repurposing; Informatics; Ivermectin; Vector control
    DOI:  https://doi.org/10.1007/s00210-025-04527-8
  48. Medicine (Baltimore). 2025 Aug 08. 104(32): e43760
    Salivary biomarkers in diabetes mellitus diagnostics: A bibliometric analysis.
    Die Hu, Yan Wu, Dongming He, Jin Rong, Meng Sun, Zhou Yu, Lihui Wu.
       BACKGROUND: Diabetes mellitus (DM) is a prevalent chronic disease worldwide, requiring accurate diagnosis and effective treatment for improved patient outcomes. Traditional glucose monitoring methods, such as venous blood sampling and fingertip glucose tests, are invasive and inconvenient. Salivary analysis, being noninvasive, easily accessible, and abundant, offers a promising diagnostic and monitoring alternative for DM. This study systematically assesses the current status and emerging trends of salivary analysis technology in DM research using bibliometric analysis.
    METHODS: This study analyzed 482 publications on DM-related salivary analysis spanning from 1990 to 2023, sourced from the Web of Science Core Collection (WoSCC). Using VOSviewer, CiteSpace, and Pajek for co-occurrence and network visualization, we examined key contributors, influential countries and institutions, prominent journals, and thematic trends within the research domain. These tools enabled a comprehensive understanding of the evolving applications and research focuses of salivary analysis in DM.
    RESULTS: From 1990 to 2023, DM-related salivary analysis research has shown a steady annual increase, particularly focusing on biomarkers such as glucose and C-reactive protein (CRP). Significant emphasis has been placed on advancing biosensors for salivary-based glucose monitoring and analyzing inflammatory responses. This study identifies key authors, pivotal research institutions, and central journals contributing to the field, shedding light on emerging trends and current research emphases.
    CONCLUSIONS: Salivary analysis represents a promising noninvasive approach for the diagnosis, monitoring, and management of DM. Despite the study's focus on data from the WoSCC, the findings provide valuable insights into the current state and future potential of this field. Future research should prioritize the development of advanced portable sensor technologies for salivary glucose monitoring and CRP-based biosensors, which have the potential to predict the progression of type 2 diabetes mellitus through inflammatory biomarkers. These innovations could significantly enhance diagnostic accuracy, patient convenience, and personalized therapeutic strategies in DM management.
    Keywords:  bibliometric analysis; diabetes mellitus; research hotspots; salivary analysis
    DOI:  https://doi.org/10.1097/MD.0000000000043760
  49. Health Sci Rep. 2025 Aug;8(8): e71167
    Analysis and Mapping of Machine Learning in the Context of Diabetes.
    Arezoo Ghamgosar, Leila Nemati-Anaraki, Maryam Zarghani, Hooman Bazri, Leila Ahmadian, Zahra Galavi, Somaye Norouzi.
       Background and Aims: The application of machine learning (ML) has started to change some important aspects of health care in diabetes. We aimed to utilize a bibliometric approach to analyze and map ML in the context of diabetes.
    Methods: To build our data set, we searched from the Web of Science Core Collection (WoSCC) database, and restricted our search from January 1, 2010 to December 31, 2023. For citation analysis, the online services of WoS were used to investigate the information content of the data set, VOSviewer and Microsoft Excel 2013 were employed to construct and visualize the bibliographic data.
    Results: Overall, 5,222 results that met the criteria were retrieved. The trend of published studies indicates that the number of publications has steadily increased over the past 14 years. The most active country was found to be USA, followed by the China and India. The highest level of cooperation with other countries belonged to the USA. The most prolific author on ML in the context of diabetes was Tien Yin Wong, with twenty-two articles affiliated at Tsinghua University; after that, Pantelis Georgiou with twenty articles affiliated at the Imperial College London, and Pau Herrero, with nineteen articles affiliated at Tijuana Institute of Technology. The most prolific research areas were machine learning, prediction models, diabetic retinopathy, deep learning, and diagnostics.
    Conclusion: The results of this study are a rich scientific source of ML for diabetes to guide researchers. This study can guide policymakers, physicians, and practitioners to help in the decision-making process. In addition, the findings will be useful for governments to guide future budgets for target studies.
    Keywords:  artificial intelligence; bibliometric analysis; diabetes; machine learning; prediction model
    DOI:  https://doi.org/10.1002/hsr2.71167
  50. Front Psychol. 2025 ;16 1617700
    An overview of the integration and development trends between arts and psychotherapy.
    Yuxing Xie, Xianhua Sun.
       Introduction: In the field of mental health, the integration of art and psychotherapy has become an important development direction. Its core mechanism lies in promoting individuals to achieve emotional release, cognitive reconstruction, and social function recovery through the creative expression of art forms, which has given rise to the important practical field of art therapy. This study aims to systematically sort out the research status and development trends in the field of art therapy from 2005 to 2024 through knowledge mapping analysis, providing references for theoretical innovation and practice standardization in this field.
    Methods: Based on the Web of Science core collection data sources, the CiteSpace bibliometric tool was used for knowledge mapping analysis of art therapy-related research. By searching keywords such as "Art Healing" and "Art Therapy," 1799 valid articles were finally included after strict screening. The analysis was carried out from multiple dimensions: basic information (changes in the number of publications, journal distribution, regional and author-institution distribution) and research content (keyword co-occurrence, cluster mining, and timeline deduction).
    Results: Art therapy research from 2005 to 2024 showed a phased growth characteristic, successively going through a germination period, a stable period, and a rapid development period. In terms of geographical distribution, Europe and the United States, represented by the United States and the United Kingdom, contributed 63% of the core literature. Research hotspots gradually shifted from early basic intervention research to the exploration of technological integration and ethical issues. It was also found that this field is highly related to multiple disciplines such as psychology and medicine, but there are limitations such as imbalanced development of cross-cultural theories.
    Discussion: Although significant progress has been made in the theory and practice of art therapy, there are still structural problems such as uneven development of cross-cultural theories, insufficient connection between technical applications and practice guidelines, and inadequate research coverage on special groups. Future research can focus on the in-depth integration of theory and practice, cross-cultural theoretical integration, construction of multi-dimensional evaluation systems, and application of virtual reality technology, providing new paths to promote theoretical innovation and practice standardization in art therapy.
    Keywords:  CiteSpace; art therapy; bibliometric analysis; cultural interconnections; health psychology; integration of the arts
    DOI:  https://doi.org/10.3389/fpsyg.2025.1617700
  51. Front Med (Lausanne). 2025 ;12 1602077
    Machine learning based insights into cardiomyopathy and heart failure research: a bibliometric analysis from 2005 to 2024.
    Muhammad Junaid Akram, Asad Nawaz, Yuan Yuxing, Jinpeng Zhang, Huang Haixin, Lingjuan Liu, Xu Qian, Jie Tian.
       Background: Cardiomyopathy and heart failure are among the most critical challenges in modern cardiology, with increasing attention to the integration of machine learning (ML) and artificial intelligence (AI) for diagnostics, risk prediction, and therapeutic strategies. This study was aimed at evaluating global research trends, influential contributions, and emerging themes in the domain of cardiomyopathy and heart failure from 2005 to 2024.
    Methodology: A comprehensive bibliometric analysis was conducted using the Web of Science Core Collection (WoSCC) database. The study utilized the R- package bibliometrix-biblioshiny, VOSviewer, Scimago Graphica and CiteSpace to analyze the publications on cardiomyopathy, heart failure, machine learning, and artificial intelligence. Key metrics examined included top institutions, countries, journals, keywords, co-authorship networks, and keyword co-occurrence patterns. Additionally, the analysis evaluated publication counts, citation trends, H-index, and collaboration metrics to identify research trends and emerging themes in the field.
    Results: A total of 2,110 publications retrieved from the last 20 years were included in the analysis. The United States of America (USA), China, and the United Kingdom (UK), emerged as leading contributors, with institutions such as Mayo Clinic and Harvard University producing high-impact research. Dominant keywords included "heart failure," "risk," "diagnosis," and "artificial intelligence," reflecting the increasing reliance on ML for predictive analytics. Thematic evolution revealed a transition from traditional classification methods to advanced techniques, including feature selection and proteomics. Influential studies, including those by Friedman PA, Noseworthy PA, and Attia ZI, showcased the transformative potential of AI in cardiology. Global collaboration networks underscored strong partnerships but highlighted disparities in contributions from low-income regions.
    Conclusion: This analysis highlights the dynamic evolution of cardiomyopathy research, emphasizing the critical role of ML and AI in advancing diagnostics and therapeutic strategies. Future research should address challenges in scalability, data standardization, and ethical considerations to ensure equitable access and implementation of these technologies, particularly in underrepresented regions.
    Keywords:  CiteSpace; VOSviewer; artificial intelligence; bibliometric; cardiomyopathy; heart failure; machine learning
    DOI:  https://doi.org/10.3389/fmed.2025.1602077
  52. J Clin Psychopharmacol. 2025 Aug 14.
    Global Insights Into Antipsychotic Research: Bridging Trends and Gaps in Schizophrenia Care (2000-2024).
    Lina M Gonzalez-Ojeda, Hernando Santamaría-García, Lina M Villegas, Catalina Trujillo-Llano, Juan F Cardona.
       BACKGROUND: Antipsychotic medications are pivotal in managing schizophrenia (SCZ), offering substantial relief from symptoms. However, their impact on functional outcomes, cognitive performance, social cognition, and quality of life remains a critical area of investigation. This bibliometric analysis examines research trends and insights into the multifaceted effects of antipsychotics on individuals with SCZ over the past 2 decades.
    METHODS: Publications from the Scopus database (2000-2024) were analyzed using VOSviewer (V1.6.18) to conduct keyword co-occurrence, co-authorship, and bibliographic mapping analyses. Key trends and thematic areas were identified through bibliometric metrics.
    RESULTS: The analysis included 2991 publications, revealing variability in annual publication rates. Schizophrenia Research was the leading journal, while the United States dominated in publication volume, author contributions, and institutional output. Key thematic areas included atypical antipsychotics, cognitive impacts, neurotransmitter mechanisms, treatment modalities, quality of life, cognitive deficits, negative symptoms, and neuroimaging studies. Despite advancements, significant gaps persist in understanding social cognition and the holistic impact of antipsychotics.
    CONCLUSIONS: This bibliometric analysis highlights the complex landscape of antipsychotic research in SCZ, underscoring progress in understanding executive functions, motor side effects, and metabolic impacts. However, the findings reveal a critical need for research into social cognition and culturally diverse populations. Addressing these gaps is essential for developing integrated treatment strategies that combine pharmacological, psychosocial, and family-based interventions. Expanding research to encompass diverse ethnic, cultural, and socioeconomic contexts is imperative for advancing global psychiatric care and ensuring equitable treatment access.
    Keywords:  adverse effects; antipsychotics; bibliometrics; cognition; quality of life; schizophrenia; social cognition
    DOI:  https://doi.org/10.1097/JCP.0000000000002062
  53. Hum Vaccin Immunother. 2025 Dec;21(1): 2546195
    Global research hotspots and trends of the vaccines: Based on ESI hot papers.
    Meixin He, Runfeng Shi, Huilin Cao, Yuyu Wang, Yue Zhu, Xinyu Wang, Liming Liang, Xu Xia.
      The aim of this study was to determine the characteristics of the Essential Science Indicators (ESI) hot papers on vaccine research and to provide a summary of the hot spots and development trends in the field. A systematic and comprehensive search for literature on vaccine research was conducted in the Web of Science Core Collection, and 81 ESI hot papers were obtained. A total of 81 ESI Hot Papers from 51 journals were identified in the domain of vaccines, of which 93.8% were highly cited. The United States emerged as the predominant nation in the field, contributing to 65.43% of the identified hot papers and 74.19% of the cited hot papers. The institutions with the highest number of hot papers and citations were from the United States and the United Kingdom. The analysis of collaboration networks revealed extensive research partnerships within the United States. A significant proportion of the ESI Hot Papers, amounting to 81.5%, was published in leading journals. The most prevalent keywords included infection, vaccine, and Corona Virus Disease 2019 (COVD-19). The analysis provided insights into vaccine research trends, helping clinicians and researchers quickly identify hot information in the field and facilitating vaccine application and development.
    Keywords:  Vaccines; hot papers; hotspot analysis; public health; trend prediction; visualization
    DOI:  https://doi.org/10.1080/21645515.2025.2546195
  54. Discov Oncol. 2025 Aug 11. 16(1): 1524
    Knowledge mapping of ferroptosis in sarcoma: a bibliometric and bioinformatics analysis (2012-2023).
    Zhen Cao, Chanjuan Qu, Fan Yang, Ning Yao, Wei Zhang, Xiaoguang Cheng, Dong Yan.
       BACKGROUND: Sarcoma is a rare and heterogeneous group of malignant tumors originating from mesenchymal tissues, which presents significant challenges for diagnosis and treatment. Ferroptosis, a newly recognized form of iron-dependent cell death, is distinct from other cell death mechanisms such as apoptosis and autophagy. Recent studies have shown that the induction of ferroptosis is an effective way to kill sarcoma cells and reduce their resistance to chemotherapeutic drugs, highlighting the importance of understanding how ferroptosis may influence the biology and treatment of sarcomas.
    METHODS: In this study, we employed three main methods, namely CiteSpace, VOSviewer, and the R package "bibliometrix", to analyze relevant literature. Publications related to ferroptosis and sarcoma in the Science Citation Index Expanded of the Web of Science Core Collection (WoSCC) database (2012-2023) were included, and bioinformatics analyses were performed using R Studio and public databases.
    RESULTS: The analysis revealed that research on sarcomas and ferroptosis has experienced a steady increase over the years, with a diverse range of research topics and collaborations established among researchers worldwide. The key findings include the identification of influential authors and institutions, prominent research clusters, and emerging research trends. The bioinformatics analysis results confirmed the significance of ferroptosis-related gene ACSF2 in different sarcomas. Notably, the scarcity of studies focusing on the relationship between sarcoma and ferroptosis has been observed, highlighting the potential for further exploration in this area.
    CONCLUSION: The integration of bibliometrics and bioinformatics provides valuable insights into the research landscape of sarcoma and ferroptosis. Future research on ferroptosis will continue to focus on its mechanisms in sarcomas including immune microenvironment, while also further exploring its potential clinical applications. We have identified a potential ferroptosis-related gene, ACSF2, which shows associations with survival in sarcoma datasets. Further testing is needed to validate its potential as a prognostic biomarker.
    Keywords:  Bibliometrics; Bioinformatics; Ferroptosis; Sarcoma; Tumors
    DOI:  https://doi.org/10.1007/s12672-025-03389-z
  55. Int Dent J. 2025 Aug 12. pii: S0020-6539(25)00240-0. [Epub ahead of print]75(5): 100954
    A Critical Correlate of QS Subject Ranking and Stanford's Top 2% Scientists in Top Dental Schools.
    Andy Wai Kan Yeung, James Kit Hon Tsoi.
       OBJECTIVE: This study aimed to evaluate the relationship between QS subject rankings and the performance of top 2% scientists in the top 20 dental schools.
    METHODS: On 28 October, 2024, data sets released by the "QS World University Rankings by Subject 2024: Dentistry" and by Stanford University about the top 2% of scientists in academia (Version 7, published in 2024) were downloaded from their official websites. The top 2% of scientists who mainly published in dentistry and were affiliated with the top 20 dental schools were identified. From 28 October to 8 November, 2024, the official websites of the top 20 dental schools were visited to manually extract their faculty staff information.
    RESULTS: There were a total of 363 top 2% scientists affiliated with these schools according to the Stanford database. Academic Centre for Dentistry Amsterdam (ACTA) had the highest total number of top 2% scientists (n = 32), but only 12 (37.5%) are current faculty staff. Meanwhile, Sichuan University has the highest number of top 2% scientists who are current faculty staff (n = 24, 100%). On average, the ratio of current faculty staff being top 2% scientists was 12.4%, and that of academic staff was 19.9%. The University of Hong Kong had the highest QS ranked dental school with above-average numbers in these two aspects. The number of top 2% scientists from these 20 dental schools positively correlated to their QS H-index score in 3 out of the last 5 years. Some limitations of the analysis include that faculty staff information was manually determined, and that some scientists had duplicate entries or inaccurate affiliation information in the database.
    CONCLUSION: The number of top 2% scientists of the top 20 dental schools positively correlated to their overall QS score and QS H-index score. The QS academic reputation score would be higher if the active top 2% scientists had more equal performance in terms of total citations received and overall composite score.
    Keywords:  Academic performance; Citation analysis; Dentistry; H-index; QS world university ranking; Top 2% scientists
    DOI:  https://doi.org/10.1016/j.identj.2025.100954
  56. PLoS One. 2025 ;20(8): e0330392
    Silent voices: Uncovering women's absence in veterinary surgery publications.
    Kelly L Bowlt Blacklock, Jill R D Mackay, Poppy Bristow, Ishita Parakh, Alina Paczesna, Fiona Mackay, Kathryn Pratschke.
       OBJECTIVE: To determine the factors associated with an author being female in Veterinary Surgery journal publications from 2002 to 2023.
    STUDY DESIGN: Retrospective observational study.
    SAMPLE POPULATION: A total of 2881 Veterinary Surgery papers published between 2002 and 2023.
    METHODS: Author gender was inferred using the Gender API and verified manually where necessary; only binary categories (male/female) were assigned. Statistical models (frequentist and Bayesian logistic regressions) were used to predict author gender based on publication year, author order (first, second, last), and surgical emphasis.
    RESULTS: Overall, 36% of the authors were female, with 43% of first authors, 37% of second authors, and 28% of last authors being women. The proportion of female first authors increased from 29% in 2010 to 60% in 2022, while female last authors ranged from 10% in 2002 to 36% in 2023. The likelihood of an author being female was influenced by the publication year, being the last author, and the subject of orthopaedics.
    CONCLUSION: Compared with the demographics of the profession, women remain underrepresented in Veterinary Surgery authorships, particularly in senior author positions and orthopaedic papers.
    DISCIPLINARY SIGNIFICANCE: The underrepresentation of female authors highlights persistent gender disparities in veterinary surgery research. Further research is required to understand the factors that influence female authorship, so that institutions and journals can implement targeted initiatives to promote gender equity.
    DOI:  https://doi.org/10.1371/journal.pone.0330392
  57. Neurosurgery. 2025 Aug 15.
    Gender Differences in Publications, Authorship, and Match Patterns Among Neurosurgical Residency Applicants.
    Logan Muzyka, Ethan A Wetzel, Alexander F Wang, Timothy R West, Ali M Nasser, Uyanga Batsaikhan, Andreas Runde, Martina Stippler, Sharona Ben-Haim, Τheresa L Williamson, Brian V Nahed.
       BACKGROUND AND OBJECTIVES: Recent efforts have highlighted gender disparities in neurosurgery in leadership, conference involvement, and scientific productivity. Despite efforts to improve diversity, systemic barriers persist. Given the weight publications carry in the neurosurgical match, this study analyzes gender differences in publication metrics among matched neurosurgical residency applicants, identifying opportunities to increase female representation.
    METHODS: Neurosurgical residents from the 2023 match were examined using PubMed, Scopus, and departmental websites for detailed publication information, program details, gender, and medical school.
    RESULTS: Of the 242 successfully matched applicants, male applicants tended to work with male senior authors (84.62% vs 76.68%, P = .044), and more female applicants worked with female senior authors (23.21% vs 15.33%, P = .045). Having a female senior author increased odds of female first authorship (odds ratio = 1.64, 95%, P < .001). Compared with female-identifying applicants, male-identifying applicants had more publications (11.80 vs 6.78, P < .001), first-authorships (3.88 vs 2.00, P < .001), higher H-indices (4.74 vs 3.27, P < .001), and more unique senior authors (5.63 vs 4.37, P = .036). Male applicants published more often in spine (P < .001). Geographically, female applicants were more likely from the West, least likely from the South (P = .036), and more likely to match at home programs than male applicants (32.8% vs 19.8%, P = .037).
    CONCLUSION: For matched neurosurgical applicants, gender of the senior author influences likelihood of junior authorship. Specifically, having female senior authors correlates with increased likelihood of publication for female applicants and is associated with female first authorship. Gender disparities persist in publications: male applicants typically publish, collaborate with senior authors, and work with male senior authors at higher rates. These results highlight systemic barriers female applicants face in preparing competitive applications and ensuring equal residency acceptance. Research instruction and active mentorship of female applicants from both male and female neurosurgical mentors is critical to improving gender disparity in neurosurgery.
    Keywords:  Applicants; Gender disparities; Mentorship; Neurosurgical residency; Publications; Senior authorship
    DOI:  https://doi.org/10.1227/neu.0000000000003674
  58. J Neurointerv Surg. 2025 Aug 14. pii: jnis-2025-023956. [Epub ahead of print]
    Global gender representation in neurointerventional surgery: a natural language processing analysis of journal publications.
    Daniela Renedo, Andrew B Koo, Abdelaziz Amllay, Nanthiya Sujijantarat, Bushra Fathima, Joseph O Haynes, Guido J Falcone, Kevin N Sheth, Sandra Abi Fadel, Michele H Johnson, Ryan Hebert, Cyprien Rivier, Charles Matouk.
       BACKGROUND: Despite increased awareness of diversity and inclusion in neurointerventional surgery, the representation of women in neurointerventional academic publishing has not been systematically quantified. We aimed to evaluate global and temporal gender trends among authors publishing in leading neurointerventional journals using natural language processing (NLP) tools.
    METHODS: We used the National Center for Biotechnology Information (NCBI) Entrez and Medline APIs (application programming interfaces) to extract metadata from all articles published between 2014 and 2024 in the Journal of NeuroInterventional Surgery and Interventional Neuroradiology, the only two journals dedicated exclusively to the field of neurointerventional surgery. For each publication, we identified the first and last authors, as well as their institutional affiliations. We applied the OpenAI GPT-4 API to infer the country of origin based on last author affiliations and to predict gender using first and last names.
    RESULTS: Across 4875 articles published between 2014 and 2024 in two leading neurointerventional surgery journals, female authorship increased modestly over time. In 2014, 10.2% of first authors and 6.1% of last authors were women, compared with 14.2% and 7.6%, respectively, in 2024. A significant upward trend in female first authorship was observed over time using the Cochran-Armitage test for trend (P=0.0002), with the strongest increases in the Americas and Asia. In contrast, no overall increase was seen in female last authorship (P=0.14), with a modest but significant trend observed only in Asia. Geographic disparities were also evident: Austria and Norway had the highest female last authorship rates (62.5% and 40.0%, respectively), whereas the US, despite contributing the most publications, had only 13.8%. The Gender Parity Index (GPI) further highlighted under-representation, with most countries falling well below parity, especially for last authorship.
    CONCLUSIONS: Analysis using artificial intelligence driven NLP methods suggests persistent gender inequalities in neurointerventional surgery authorship with variation across countries. Although female representation has improved over the past decade, progress is uneven. These findings underscore the need for targeted efforts to promote equity in academic vascular neurosurgery globally.
    Keywords:  Brain; Intervention
    DOI:  https://doi.org/10.1136/jnis-2025-023956
  59. ANZ J Surg. 2025 Aug 13.
    Publication Rates of Abstracts Presented at the Urological Society of Australia and New Zealand Annual Scientific Meeting Keith Kirkland and Villis Marshall Session: A Decade-Long Review.
    Cheryl Fung, Lequang T Vo, David Armany, Balasubramaniam Indrajit, Simon V Bariol, Tania Hossack, Sriskanthan Baskaranathan, David Ende, Henry H Woo.
       BACKGROUND: The publication rate of abstracts at scientific meetings reflects research quality and impact, highlighting its dissemination within the academic and clinical communities. The Keith Kirkland and Villis Marshall (KK/VM) Session, held annually at the Urological Society of Australia and New Zealand (USANZ) Annual Scientific Meeting (ASM), features top abstracts from Urology SET Trainees. While the Board selects abstracts for presentation, their publication rates remain unclear. This study aims to determine the full-article publication rate of abstracts presented at the KK/VM session from 2012 to 2022.
    METHODS: The published Scientific Program of the USANZ ASM from 2012 to 2022 was retrospectively reviewed. All abstracts accepted for presentation at the KK/VM sessions were identified from the named plenary session. These abstracts were tracked for their subsequent publication status. Successful publication was defined as those identified in a search on PubMed using the abstract title and author name. Analysis of the successful publication was conducted.
    RESULTS: One hundred and thirty-five abstracts were identified. 51.85% were subsequently published in peer-reviewed journals, most commonly in the BJU International (27.14%), The Journal of Urology (18.57%), and the ANZ Journal of Surgery (8.57%). The average time to publication was 14.58 months. The proportion of prospective studies among published (51.4%) and unpublished (52.3%) abstracts was similar.
    CONCLUSION: The USANZ ASM KK/VM session achieved a 51.85% full-article publication rate from 2012 to 2022, surpassing the broader USANZ ASM rate. This underscores the high quality of research by Urology SET Trainees. Targeted support could boost publication rates, improving urology research dissemination.
    Keywords:  KK/VM session; USANZ ASM; abstract publication rate; peer‐reviewed journals; urology SET trainees; urology research
    DOI:  https://doi.org/10.1111/ans.70290
  60. Environ Sci Pollut Res Int. 2025 Aug 11.
    A systematic review of the life cycle cost estimation of upgrading buildings for sustainability.
    Ali Tighnavard Balasbaneh, Willy Sher, Jingnan Li.
      In this study we have identified and evaluated literature related to refurbishment, renovation, retrofit and/or repair in the construction sector. We present a bibliometric evaluation along with a systematic critical review to identify materials used in upgrading buildings. We located 47 such publications. We found that more studies focus on renovation than those that address refurbishment, retrofit or repair, with respective counts of 19, 17, 12 and 10. The number of publications has fluctuated over the past few years. In some years, such as 2015, 2018 and 2023, an increasing number of studies were published, while there was a decline in 2015 to 2017 and 2020. Notwithstanding this, spikes in publication numbers occurred multiple times. Furthermore, the citation trend was generally upwards, suggesting that research in this field has gained increasing academic attention and influence over time. The originality of this study reveals the uncertainty of researchers in selecting cost evaluation methods when upgrading buildings. The trend suggests that further innovation and clarification is needed to enhance cost assessment methodologies. Evaluation of system boundaries revealed that most studies do not consider the end-of-life stage when evaluating different materials to upgrade buildings. To achieve an optimum building upgrade solution, single-objective optimization such as evaluating cost or LCA is insufficient, and multi-objective assessment methods need to be considered. Further research is needed to determine which upgrading strategies can effectively influence costs in optimization energy strategies.
    Keywords:  Construction industry; Life cycle cost; Refurbishment; Renovation, Retrofit; Sustainability
    DOI:  https://doi.org/10.1007/s11356-025-36757-x
  61. Int J Surg. 2025 Aug 11.
    Precision oncology for NSCLC: a bibliometric exploration of emerging trends and research priorities.
    Liping Zhang, Yanhui Yang, Tianhu Wang.
      
    DOI:  https://doi.org/10.1097/JS9.0000000000003177
  62. Rev Med Inst Mex Seguro Soc. 2025 Aug 14. 63(5): e6685
    Impact of incorrect affiliations on the recognition of Mexican scientific institutions.
    Paloma Gradilla-Magaña, Antonio Cisneros-Barrios, Aldo Barajas-Ochoa, Julio Enrique Castañeda-Delgado, Cesar Ramos-Remus.
       Background: Scientific productivity is a key parameter for measuring the effectiveness of healthcare institutions. Incorrect institutional names in affiliations can have legal implications and affect their visibility.
    Objective: To analyze the prevalence and impact of incorrect (apocryphal) institutional affiliations in Mexican scientific publications.
    Material and methods: A bibliometric analysis was conducted using PubMed and Scopus on publications from 20 Mexican institutions and universities. The affiliation loss ratio was calculated as the proportion of publications with apocryphal affiliations compared to those using the official name, and impact on institutional h-index was assessed to quantify visibility losses.
    Results: The average affiliation loss ratio was 13.92% (range: 2.1% to 66.5%), with highest rates for the Instituto Nacional de Salud Pública (66.5%), Instituto de Oftalmología Conde de Valenciana (62.6%), and Instituto Nacional de Medicina Genómica (32.9%). The analysis of h-index showed that correcting apocryphal affiliations could increase this metric by up to 6 points for some institutions, potentially improving international ranking positions.
    Conclusion: Incorrect institutional affiliations are common in Mexican scientific publications and significantly affect health institutions' visibility and international recognition. Prompt correction of this problem would improve Mexico's position in international rankings.
    Keywords:  Databases, Bibliographic; Mexico; Organizational Affiliation; Periodicals as Topic; Publishing
    DOI:  https://doi.org/10.5281/zenodo.16748326
  63. PLoS One. 2025 ;20(8): e0327344
    Do organisms need an impact factor? Citations of key biological resources including model organisms reveal usage patterns and impact.
    Agata Piekniewska, Martijn Roelandse, Kevin C Kent Lloyd, Ian Korf, Stephen Randal Voss, Giovanni de Castro, Diogo M Magnani, Zoltan Varga, Christina James-Zorn, Marko Horb, Jeffery S Grethe, Anita Bandrowski.
      Research resources like transgenic animals and antibodies are the workhorses of biomedicine, enabling investigators to relatively easily study specific disease conditions. As key biological resources, transgenic animals and antibodies are often validated, maintained, and distributed from university-based stock centers. As these centers heavily rely on grant funding, it is critical that they are cited by investigators so that usage can be tracked. However, unlike systems for tracking the impact of papers, the conventions and systems for tracking key resource usage and impact lag. Previous studies have shown that about 50% of the resources are not findable, making the studies they support irreproducible, but also makes tracking resources difficult. The RRID (Research Resource Identifiers) project is filling this gap by working with journals and resource providers to improve citation practices and to track the usage of these key resources. Here, we reviewed 10 years of citation practices for five university based stock centers, characterizing each reference into two broad categories: findable (authors could use the RRID, stock number, or full name) and not findable (authors could use a nickname or a common name that is not unique to the resource). The data revealed that when stock centers asked their communities to cite resources by RRID, in addition to helping stock centers more easily track resource usage by increasing the number of RRID papers, authors shifted from citing resources predominantly by nickname (~50% of the time) to citing them by one of the findable categories (~85%) in a matter of several years. In the case of one stock center, the MMRRC, the improvement in findability is also associated with improvements in the adherence to NIH rigor criteria, as determined by a significant increase in the Rigor and Transparency Index for studies using MMRRC mice. From these data, it was not possible to determine whether outreach to authors or changes to stock center websites drove better citation practices, but findability of research resources and rigor adherence were improved.
    DOI:  https://doi.org/10.1371/journal.pone.0327344
  64. CJEM. 2025 Aug 13.
    Authorship equity in The Canadian Journal of Emergency Medicine: an analysis of articles between 2000 and 2019.
    Dawn Gardner, Alyson Byrne, Gillian Sheppard.
       OBJECTIVES/BACKGROUND: Women are underrepresented in prestigious authorship positions. As per the Canadian Medical Association (CMA), 31.3% of emergency department (ED) physicians identify as women or female. This is the first study to explore whether the corresponding gender/sex proportion of ED physicians in Canada each year is reflected in prestigious authorship in the Canadian Journal of Emergency Medicine (CJEM) between 2000 and 2019.
    METHODS: A cross-sectional analysis was conducted of the first and last authors of original research articles in the CJEM from 2000 to 2019. Our data collection yielded 623 original research articles. Descriptive statistical techniques were used to analyze authorship in the CJEM and the proportion of women/female emergency physicians in Canada over the twenty-year period.
    RESULTS: Of 623 total articles, 64.7% have a man as the first author and 35.3% have a woman as the first author. Of 546 articles with three or more authors, 72.0% have a man as the last author and 28.0% have a woman as the last author. There are several years where the proportion of women in first or last authorship is lower than the proportion of women/females in emergency medicine.
    CONCLUSIONS: Our study shows that the proportion of women in prestigious authorship positions in the CJEM exceeds the proportion of women/female ED physicians in Canada between the years of 2000 and 2019. As the proportion of women/females has increased in emergency medicine, the proportion of women with prestigious authorship positions has also increased in the CJEM. This suggests that emergency medicine in Canada may be a welcoming field for women who want to publish research at a prestigious level and practice medicine.
    Keywords:  Authorship equity; Authorship gender/sex; Emergency medicine Canada; Emergency medicine authorship; Gender gap authorship; Women/female representation authorship; Women/female representation emergency medicine
    DOI:  https://doi.org/10.1007/s43678-025-00965-8
  65. Biosystems. 2025 Aug 07. pii: S0303-2647(25)00162-5. [Epub ahead of print]256 105552
    The scientometric approach to Code Biology: What the title tells about the field.
    Omar Paredes, Robert Prinz.
      Code Biology has emerged as a conceptual framework for investigating how information is encoded, transmitted, and interpreted in living systems. Building on recent efforts to catalog biological codes across disciplines, we present the first comprehensive scientometric analysis of the field. Using a curated corpus of publications explicitly invoking the term code, we apply full-text natural language processing and unsupervised topic modeling to map the intellectual landscape of Code Biology. Our analysis reveals 24 distinct thematic clusters, ranging from molecular mechanisms and regulatory architectures to neural information processing and philosophical discourse on meaning and organization. This approach offers insights that conventional literature reviews often miss-uncovering latent patterns, inter-topic correlations, and conceptual blind spots. In doing so, we expose the field's current fragmentation into isolated knowledge niches and highlight the need for integrative models of how biological codes interact across scales. Temporal and geographical analyses reveal distinct phases in the development of Code Biology, shifting from gene-centric and mechanistic views to increasingly symbolic, cognitive, and systems-oriented paradigms. Collaboration network analysis further shows the emergence of modular scientific communities and identifies key interdisciplinary contributors shaping the field. Taken together, our results establish the foundation for a new branch of code biology, dedicated to the empirical and conceptual mapping of coding processes in biology based on literature. We propose key research directions, including the structural grammar of neural codes, the role of prebiotic and evolutionary codes in transitions of life, and the intersection between biological and artificial coding systems. This work provides not only a roadmap for future research but also a call to develop standardized frameworks capable of bridging molecular, neural, and symbolic dimensions of biological information processing.
    DOI:  https://doi.org/10.1016/j.biosystems.2025.105552
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