bims-minfam Biomed News
on Inflammation and metabolism in ageing and cancer
Issue of 2025–06–15
five papers selected by
Ayesh Seneviratne, McMaster University
  1. Clonal hematopoiesis driven by microbial metabolite.
  2. Senescence-related proteins in blood predict aging traits.
  3. Increasing transparency and recognition in peer review.
  4. An inside job-CHIP infiltrates and promotes cancer.
  5. Physical activity and Alzheimer's disease: a call for evidence incorporation.
  1. Nat Aging. 2025 Jun 12.
    Clonal hematopoiesis driven by microbial metabolite.
    Yahyah Aman.
      
    DOI:  https://doi.org/10.1038/s43587-025-00912-3
  2. Nat Aging. 2025 Jun 10.
    Senescence-related proteins in blood predict aging traits.
      
    DOI:  https://doi.org/10.1038/s43587-025-00891-5
  3. Nat Aging. 2025 Jun 11.
    Increasing transparency and recognition in peer review.
      
    DOI:  https://doi.org/10.1038/s43587-025-00913-2
  4. Immunity. 2025 Jun 10. pii: S1074-7613(25)00235-3. [Epub ahead of print]58(6): 1375-1377
    An inside job-CHIP infiltrates and promotes cancer.
    Brian Y Soong, Nader Yatim, Miriam Merad.
      Somatic mutations in hematopoietic stem cells can lead to clonal hematopoiesis of indeterminate potential (CHIP), a frequent condition associated with many age-related diseases including solid cancer. In the New England Journal of Medicine, Pich et al. report that tumor-infiltrating CHIP correlates with worsened cancer prognosis and clinical outcomes, providing evidence for the impact of mutated immune cells on disease progression.
    DOI:  https://doi.org/10.1016/j.immuni.2025.05.014
  5. J Prev Alzheimers Dis. 2025 Jun 07. pii: S2274-5807(25)00168-2. [Epub ahead of print] 100225
    Physical activity and Alzheimer's disease: a call for evidence incorporation.
    Juan Luis Sánchez-Sánchez, Philipe de Souto Barreto.
      
    Keywords:  Alzheimer disease; Physical exercise
    DOI:  https://doi.org/10.1016/j.tjpad.2025.100225
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